Nicholas Galifianakis, MD
Professor
Neurology
School of Medicine

Galifianakis' research interests include outcomes in deep brain stimulation for patients with Parkinson's disease and essential tremor, such as with the use of new interventional MRI techniques. He also is interested in defining types of essential tremor and developing more complete models of care for advanced Parkinson's disease.

Galifianakis earned his medical degree and completed a neurology residency at the University of Southern California, where he served as chief resident. He completed a movement disorders fellowship at the University of Pennsylvania and UCSF.

Galifianakis also sees patients at the Parkinson's Disease Research, Education and Clinical Center in San Francisco, a Veterans Affairs center of excellence. He is a member of the American Academy of Neurology and International Parkinson and Movement Disorder Society.

• 10 Year Clinical Outcomes of Subthalamic Nucleus versus Pallidal Deep Brain Stimulation for Parkinson’s Disease: VA/NINDS CSP #468F (4312).
  Neurology 2021 Jill Ostrem, Ping Luo, Frances Weaver, Kenneth Follett, Nicholas Galifianakis, Eugene Lai, Jeff Bronstein, John Duda, Kathryn Holloway, Aliya Sarwar, Matthew Brodsky, Kathryn Chung, Meredith Spindler,…
• The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism.
  NPJ Parkinson's disease 2021 Tanner CM, Cummings SR, Schwarzschild MA, Brown EG, Dorsey ER, Espay AJ, Galifianakis NB, Goldman SM, Litvan I, Luthra N, McFarland NR, Mitchell KT, Standaert DG, Bauer DC, Greenspan SL, Beck JC, …
• The presence of a caregiver is associated with patient outcomes in patients with Parkinson's disease and atypical parkinsonisms.
  Parkinsonism & related disorders 2020 Prizer LP, Kluger BM, Sillau S, Katz M, Galifianakis NB, Miyasaki JM
• Medical education in movement disorders during the COVID-19 pandemic.
  Parkinsonism & related disorders 2020 Zuzuárregui JRP, Bledsoe IO, Brown EG, Dietiker CG, Galifianakis NB
• Predictors of general and health-related quality of life in Parkinson's disease and related disorders including caregiver perspectives.
  Parkinsonism & related disorders 2020 Trang I, Katz M, Galifianakis N, Fairclough D, Sillau SH, Miyasaki J, Kluger BM
• Nonsurgical Management of an Exposed Deep Brain Stimulation Lead.
  2020 Ethan G. Brown, Monica Volz, Susan Heath, Nicholas B. Galifianakis, Jill L. Ostrem
• Remote telemedicine evaluation of deep brain stimulation candidacy: Retrospective cohort analysis.
  Neurology. Clinical practice 2020 Witek N, Heath SL, Ouyang B, Tanner CM, Galifianakis NB
• Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study.
  The Lancet. Neurology 2020 Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, …
• Comparison of Integrated Outpatient Palliative Care With Standard Care in Patients With Parkinson Disease and Related Disorders: A Randomized Clinical Trial.
  JAMA neurology 2020 Kluger BM, Miyasaki J, Katz M, Galifianakis N, Hall K, Pantilat S, Khan R, Friedman C, Cernik W, Goto Y, Long J, Fairclough D, Sillau S, Kutner JS
• Associations between spiritual well-being and quality of life in Parkinson disease.
  Annals of palliative medicine 2020 Miyasaki JM, Kluger BM, Sillau S, Katz M, Galifianakis N, Prizer LP
• Correlates of spiritual wellbeing in persons living with Parkinson disease.
  Annals of palliative medicine 2019 Prizer LP, Kluger BM, Sillau S, Katz M, Galifianakis N, Miyasaki JM
• Education Research: An experiential outpatient teleneurology curriculum for residents.
  Neurology 2019 Afshari M, Witek NP, Galifianakis NB
• Patient Experience with Rechargeable Implantable Pulse Generator Deep Brain Stimulation for Movement Disorders.
  Stereotactic and functional neurosurgery 2019 Mitchell KT, Volz M, Lee A, San Luciano M, Wang S, Starr PA, Larson P, Galifianakis NB, Ostrem JL
• Does outpatient palliative care improve patient-centered outcomes in Parkinson's disease: Rationale, design, and implementation of a pragmatic comparative effectiveness trial.
  Contemporary clinical trials 2019 Kluger BM, Katz M, Galifianakis N, Pantilat SZ, Kutner JS, Sillau S, Gritz M, Jones J, Fairclough D, Sumrall M, Hall K, Miyasaki J
• Practical Implementation Strategies for Outpatient Neurology Palliative Care.
  Neuropalliative Care 2019 Nicholas B. Galifianakis, Maya Katz, Benzi M. Kluger
• Long-Term Outcomes of Bilateral Pallidal Deep Brain Stimulation for X-Linked Dystonia and Parkinsonism.
  Stereotactic and functional neurosurgery 2018 Kilbane C, Witt J, Galifianakis NB, Glass GA, Volz M, Heath S, Starr PA, Ostrem JL
• Top Ten Tips Palliative Care Clinicians Should Know About Parkinson's Disease and Related Disorders.
  Journal of palliative medicine 2018 Katz M, Goto Y, Kluger BM, Galifianakis NB, Miyasaki JM, Kutner JS, Jones CA, Pantilat SZ
• Neuropalliative care: Priorities to move the field forward.
  Neurology 2018 Creutzfeldt CJ, Kluger B, Kelly AG, Lemmon M, Hwang DY, Galifianakis NB, Carver A, Katz M, Curtis JR, Holloway RG
• Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Wang DD, de Hemptinne C, Miocinovic S, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA
• Developing a First-of-its-Kind Telemedicine Rotation for Neurology Residents (P3.341).
  Neurology 2018 Mitra Afshari, Nicholas B. Galifianakis
• Telemedicine Use for Movement Disorders: A Global Survey.
  Telemedicine journal and e-health : the official journal of the American Telemedicine Association 2018 Hassan A, Dorsey ER, Goetz CG, Bloem BR, Guttman M, Tanner CM, Mari Z, Pantelyat A, Galifianakis NB, Bajwa JA, Gatto EM, Cubo E
• National randomized controlled trial of virtual house calls for Parkinson disease.
  Neurology 2017 Beck CA, Beran DB, Biglan KM, Boyd CM, Dorsey ER, Schmidt PN, Simone R, Willis AW, Galifianakis NB, Katz M, Tanner CM, Dodenhoff K, Aldred J, Carter J, Fraser A, Jimenez-Shahed J, Hunter C, Spindler M…
• Virtual visits for Parkinson disease: A multicenter noncontrolled cohort.
  Neurology. Clinical practice 2017 Korn RE, Wagle Shukla A, Katz M, Keenan HT, Goldenthal S, Auinger P, Zhu W, Dodge M, Rizer K, Achey MA, Byrd E, Barbano R, Richard I, Andrzejewski KL, Schwarz HB, Dorsey ER, Biglan KM, Kang G, …
• Parkinson's disease patient preference and experience with various methods of DBS lead placement.
  Parkinsonism & related disorders 2017 LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M
• Chronic multisite brain recordings from a totally implantable bidirectional neural interface: experience in 5 patients with Parkinson's disease.
  Journal of neurosurgery 2017 Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Ostrem JL, Galifianakis NB, Luciano MS, Wang SS, Ziman N, Taylor R, Starr PA
• Palliative care and Parkinson's disease: Meeting summary and recommendations for clinical research.
  Parkinsonism & related disorders 2017 Kluger BM, Fox S, Timmons S, Katz M, Galifianakis NB, Subramanian I, Carter JH, Johnson MJ, Richfield EW, Bekelman D, Kutner JS, Miyasaki J
• Problematic Mobile Gaming in Parkinson's Disease: An Impulse Control Disorder for the Smartphone.
  Movement disorders clinical practice 2016 Galifianakis NB, Byrd EA, Ostrem JL, Tanner CM, Racine CA
• Gamma Oscillations in the Hyperkinetic State Detected with Chronic Human Brain Recordings in Parkinson's Disease.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Swann NC, de Hemptinne C, Miocinovic S, Qasim S, Wang SS, Ziman N, Ostrem JL, San Luciano M, Galifianakis NB, Starr PA
• Innovative approaches in caring for people with Parkinson disease: Filling the gaps.
  Neurology. Clinical practice 2016 Schneider R, Galifianakis NB
• National Randomized Controlled Trial of Virtual House Calls for People with Parkinson's Disease: Interest and Barriers.
  Telemedicine journal and e-health : the official journal of the American Telemedicine Association 2016 Dorsey ER, Achey MA, Beck CA, Beran DB, Biglan KM, Boyd CM, Schmidt PN, Simone R, Willis AW, Galifianakis NB, Katz M, Tanner CM, Dodenhoff K, Ziman N, Aldred J, Carter J, Jimenez-Shahed J, Hunter C, …
• Subthalamic local field potentials in Parkinson's disease and isolated dystonia: An evaluation of potential biomarkers.
  Neurobiology of disease 2016 Wang DD, de Hemptinne C, Miocinovic S, Qasim SE, Miller AM, Ostrem JL, Galifianakis NB, San Luciano M, Starr PA
• Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease.
  Journal of neurosurgery 2015 Ostrem JL, Ziman N, Galifianakis NB, Starr PA, Luciano MS, Katz M, Racine CA, Martin AJ, Markun LC, Larson PS
• Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease.
  Nature neuroscience 2015 de Hemptinne C, Swann NC, Ostrem JL, Ryapolova-Webb ES, San Luciano M, Galifianakis NB, Starr PA
• Parkinson’s Disease (PD) Patient Experience with the ClearPoint(TM) Interventional MRI (iMRI)-Guided Method for Placement of Deep Brain Stimulation (DBS) Leads (P6.085).
  Neurology 2015 Sara LaHue, Maya Katz, Nicholas Galifianakis, Marta San Luciano, Nathan Ziman, Sarah Wang, Caroline Racine, Philip Starr, Paul Larson, Jill Ostrem
• Sensitive measures of executive dysfunction in non-demented Parkinson's disease.
  Parkinsonism & related disorders 2014 Bott NT, Johnson ET, Schuff N, Galifianakis N, Subas T, Pollock J, Pressman P, Kramer JH, Possin KL
• 203 Application Accuracy of a Second Generation Interventional MRI Stereotactic Platform.
  Neurosurgery 2013 Paul Larson, Philip A. Starr, Jill L. Ostrem, Nicholas Galifianakis, Marta San Luciano Palenzuela, Alastair Martin
• Subthalamic nucleus neurons are synchronized to primary motor cortex local field potentials in Parkinson's disease.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Shimamoto SA, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Miller KJ, Starr PA
• Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease.
  Proceedings of the National Academy of Sciences of the United States of America 2013 de Hemptinne C, Ryapolova-Webb ES, Air EL, Garcia PA, Miller KJ, Ojemann JG, Ostrem JL, Galifianakis NB, Starr PA
• Globus pallidus interna deep brain stimulation for tardive dyskinesia: case report and review of the literature.
  Parkinsonism & related disorders 2012 Spindler MA, Galifianakis NB, Wilkinson JR, Duda JE
• Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement.
  Clinical neurology and neurosurgery 2012 Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS
• Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia.
  Tremor and Other Hyperkinetic Movements 2012 Camilla Kilbane, Jill Ostrem, Nicholas Galifianakis, Jamie Grace, Leslie Markun, Graham A. Glass
• Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia.
  Tremor and other hyperkinetic movements (New York, N.Y.) 2012 Kilbane C, Ostrem J, Galifianakis N, Grace J, Markun L, Glass GA
• Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2012 Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA
• Oscillations in sensorimotor cortex in movement disorders: an electrocorticography study.
  Brain : a journal of neurology 2012 Crowell AL, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Shimamoto S, Lim DA, Starr PA
• Overview of common movement disorders.
  Continuum (Minneapolis, Minn.) 2010 Ostrem JL, Galifianakis NB
• Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine.
  Brain research 2008 Holschneider DP, Yang J, Sadler TR, Galifianakis NB, Bozorgzadeh MH, Bading JR, Conti PS, Maarek JM