Ngoc Ly, MD, MPH
Professor
Pediatrics
School of Medicine

Ly is a pediatric pulmonologist with clinical and research interests in asthma, cystic fibrosis (CF), exercise testing and bronchopulmonary dysplasia (BDP). She is a lead investigator on several cystic fibrosis and asthma clinical research projects and trials, including those funded by Cystic Fibrosis Foundation (CFF) and TDN, National Science Foundation (NSF) and National Institute of Health (NIH).

Ly is the program director of the HRSA Maternal and Child Health Pediatric Pulmonary Center (PPC) at UCSF. The purpose of the PPC is to improve the health status of infants, children, and adolescents with chronic respiratory conditions, sleep issues, and other related special health care needs through graduate and post-graduate level interdisciplinary training of health professionals and through working within collaborative systems that promote family-centered care, public health practices, and cultural competence to address health disparities and expand access to care.

Ly is devoted to mentoring students, residents, fellows, and junior faculty.

• Time to be blunt: Substance use in cystic fibrosis.
  Pediatric pulmonology 2024 Vaziri S, McGarry ME, Huang CY, Cuneo AA, Willen SM, Iwanaga K, Neemuchwala F, Gibb ER, Chan M, Ly NP
• Cystic fibrosis transmembrane conductance regulator modulator administration to a F508del heterozygous infant with meconium pseudocyst and short bowel syndrome: A case report.
  Pediatric pulmonology 2023 Stoffella S, Ly N, McGarry M, Neemuchwala F, Church G, Chan M, Cuneo A, Omori M, Gibb E
• Diversity, Equity, and Inclusion in the Pediatric Pulmonary Workforce: An Official American Thoracic Society Workshop Report.
  Annals of the American Thoracic Society 2023 Stephenson N, Forno E, Laguna TA, Lovinsky-Desir S, Moore PE, Sheares BJ, Kazmerski TM, Udoko MN, Lypson ML, Harding LRW, Wilkes DS, Adair DJ, Afolabi F, Balasubramaniam V, Ale GJB, Castner LM, Ghera …
• Ethnic differences in staphylococcus aureus acquisition in cystic fibrosis.
  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2023 McGarry ME, Huang CY, Ly NP
• Pediatric Medical Traumatic Stress and Trauma-Informed Care in Pediatric Chronic Illness: A Healthcare Provider Survey.
  The Journal of pediatrics 2023 Cuneo AA, Sifflet C, Bardach N, Ly N, von Scheven E, Perito ER
• Medical traumatic stress in cystic fibrosis: A qualitative analysis.
  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2023 Cuneo AA, Outram S, Marsac ML, Vendlinski S, Heyman MB, Ly N, von Scheven E, Perito ER
• Changes in the Use of Invasive and Noninvasive Mechanical Ventilation in Pediatric Asthma: 2009-2019.
  Annals of the American Thoracic Society 2023 Smith MA, Dinh D, Ly NP, Ward SL, McGarry ME, Zinter MS
• Plant-derived nanovesicles: Current understanding and applications for cancer therapy.
  Bioactive materials 2022 Ly NP, Han HS, Kim M, Park JH, Choi KY
• 323 It's time to be blunt—a deeper investigation of attitudes and usage of marijuana, cannabidiol, and cigarettes in the cystic fibrosis community.
  Journal of Cystic Fibrosis 2022 S. Vaziri, M. McGarry, A. Cuneo, M. Chan, E. Gibb, K. Iwanaga, F. Neemuchwala, N. Ly
• 483 Describing the oropharyngeal microbiome in children with cystic fibrosis transmembrane regulator related metabolic syndrome.
  Journal of Cystic Fibrosis 2022 K. Tuveson, M. Zinter, M. McGarry, K. Iwanaga, M. Chan, G. Reyes, J. Blum, M. Simon, N. Ly
• 77 Improving transition from pediatric to adult cystic fibrosis care: A quality improvement initiative.
  Journal of Cystic Fibrosis 2022 K. Tuveson, T. Raffino, D. Dawson, R. Kelekian, F. Ostrem, S. Stofella, M. Omori, E. Norona, M. McGarry, M. Chan, E. Gibb, N. Ly, F. Neemuchwala
• Determinants of lung function across childhood in the Severe Asthma Research Program (SARP) 3.
  The Journal of allergy and clinical immunology 2022 Gaffin JM, Petty CR, Sorkness RL, Denlinger LC, Phillips BR, Ly NP, Gaston B, Ross K, Fitzpatrick A, Bacharier LB, DeBoer MD, Teague WG, Wenzel SE, Ramratnam S, Israel E, Mauger DT, Phipatanakul W, …
• Pediatric Medical Traumatic Stress in Inflammatory Bowel Disease, Pancreatitis, and Cystic Fibrosis.
  Journal of pediatric gastroenterology and nutrition 2022 Cuneo AA, Abu-El-Haija M, Marsac ML, Verstraete S, Heyman MB, Ly N, Perito ER
• Food insecurity and mental health during the COVID-19 pandemic in cystic fibrosis households.
  Pediatric pulmonology 2022 Lim JT, Ly NP, Willen SM, Iwanaga K, Gibb ER, Chan M, Church GD, Neemuchwala F, McGarry ME
• Patient and Provider Experience With Cystic Fibrosis Telemedicine Clinic.
  Frontiers in pediatrics 2021 Hendra K, Neemuchwala F, Chan M, Ly NP, Gibb ER
• 271: Loss of control, shifts in illness identity, and perceived vulnerability underlie traumatic illness–related experiences in patients with cystic fibrosis.
  Journal of Cystic Fibrosis 2021 A. Cuneo, S. Outram, N. Ly, E. Gibb, E. Perito
• 548: Evaluation of elexacaftor/tezacaftor/ivacaftor on pulmonary function in cystic fibrosis patients.
  Journal of Cystic Fibrosis 2021 A. Hamad, D. Hiner, V. Jue, Y. Shi, S. Stoffella, S. Thakar, J. Budzik, F. Chau-Etchepare, D. Dawson, E. Gibb, S. Jahwar, R. Kamerman-Kretzmer, M. Kleinhenz, N. Ly, B. Morrissey, K. Nandalike, A. …
• The association of plasma IL-6 with measures of asthma morbidity in a moderate-severe pediatric cohort aged 6-18 years.
  The journal of allergy and clinical immunology. In practice 2021 Permaul P, Peters MC, Petty CR, Cardet JC, Ly NP, Ramratnam SK, Ross K, Fitzpatrick A, Israel E, Bacharier LB, Phipatanakul W, National Heart, Lung, and Blood Institute Severe Asthma Research Program-…
• PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment.
  The Journal of allergy and clinical immunology 2021 Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, …
• Early acquisition and conversion of Pseudomonas aeruginosa in Hispanic youth with cystic fibrosis in the United States.
  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2020 McGarry ME, Huang CY, Nielson DW, Ly NP
• Outcomes of Children With Cystic Fibrosis Admitted to PICUs.
  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2020 Smith MA, McGarry ME, Ly NP, Zinter MS
• The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.
  Journal of biopharmaceutical statistics 2020 Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, …
• Functional Profiling of CFTR-Directed Therapeutics Using Pediatric Patient-Derived Nasal Epithelial Cell Models.
  Frontiers in pediatrics 2020 Park JK, Shrivastava A, Zhang C, Pollok BA, Finkbeiner WE, Gibb ER, Ly NP, Illek B
• Severe Asthma: Clinical Studies and Clinical Trials in Children.
  2020 Ngoc P. Ly
• Severe asthma during childhood and adolescence: A longitudinal study.
  The Journal of allergy and clinical immunology 2019 Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, Israel E, Levy B, Fahy JV, Castro M,…
• Development and initial validation of the Asthma Severity Scoring System (ASSESS).
  The Journal of allergy and clinical immunology 2019 Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, …
• Clinical significance of the bronchodilator response in children with severe asthma.
  Pediatric pulmonology 2019 Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-…
• Regional variations in longitudinal pulmonary function: A comparison of Hispanic and non-Hispanic subjects with cystic fibrosis in the United States.
  Pediatric pulmonology 2019 McGarry ME, Neuhaus JM, Nielson DW, Ly NP
• Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Zinter MS, Dvorak CC, Mayday MY, Iwanaga K, Ly NP, McGarry ME, Church GD, Faricy LE, Rowan CM, Hume JR, Steiner ME, Crawford ED, Langelier C, Kalantar K, Chow ED, Miller S, Shimano K, Melton A, Yanik …
• Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children.
  The Journal of allergy and clinical immunology 2019 Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, …
• Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
  The Journal of allergy and clinical immunology 2019 Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour …
• Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.
  BMC pulmonary medicine 2018 DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, …
• Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children.
  bioRxiv 2018 Matt S Zinter, Christopher C Dvorak, Madeline Y Mayday, Kensho Iwanaga, Ngoc P Ly, Meghan E McGarry, Gwynne D Church, Lauren E Faricy, Courtney M Rowan, Janet R Hume, Marie E Steiner, Emily D Crawford…
• Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations.
  The New England journal of medicine 2018 Jackson DJ, Bacharier LB, Mauger DT, Boehmer S, Beigelman A, Chmiel JF, Fitzpatrick AM, Gaffin JM, Morgan WJ, Peters SP, Phipatanakul W, Sheehan WJ, Cabana MD, Holguin F, Martinez FD, Pongracic JA, …
• Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis.
  Pediatric pulmonology 2017 McGarry ME, Neuhaus JM, Nielson DW, Burchard E, Ly NP
• Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.
  The journal of allergy and clinical immunology. In practice 2017 Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, …
• Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.
  American journal of respiratory and critical care medicine 2017 Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, …
• 0888 AUTO-ADJUSTING CPAP: AN OPTION FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA IN OBESE CHILDREN.
  Sleep 2017 LM DelRosso, T MDuba, K Iwanaga, E Gibb, J Dy, G Church, N Ly
• A 6-Month-Old Infant With Different Capnography Values in Polysomnography.
  Chest 2017 DelRosso LM, Palacay P, Ly NP
• In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies.
  Pediatric pulmonology 2017 McGarry ME, Illek B, Ly NP, Zlock L, Olshansky S, Moreno C, Finkbeiner WE, Nielson DW
• Severe Postictal Hypoxemia-Associated Seizure in a 12-Year-Old Child.
  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2016 DelRosso LM, Hoque R, Mitchell C, Ly NP
• A 16-Year-Old Boy with Refractory Epilepsy and Sleep-Disordered Breathing.
  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2016 DelRosso LM, Hoque R, Contreras MB, Ly NP
• Asthma, FEF25–75, and Hospitalizations in Children.
  Pediatric Allergy Immunology and Pulmonology 2013 Elizabeth R. Gibb, Shannon M. Thyne, Daniel N. Kaplan, Ngoc P. Ly
• Asthma, FEF25-75, and Hospitalizations in Children.
  Pediatric allergy, immunology, and pulmonology 2013 Gibb ER, Thyne SM, Kaplan DN, Ly NP
• Maternal intestinal flora and wheeze in early childhood.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2012 Lange NE, Celedón JC, Forno E, Ly NP, Onderdonk A, Bry L, Delaney ML, DuBois AM, Gold DR, Weiss ST, Litonjua AA
• Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011 McLoughlin RM, Calatroni A, Visness CM, Wallace PK, Cruikshank WW, Tuzova M, Ly NP, Ruiz-Perez B, Kattan M, Bloomberg GR, Lederman H, Gern JE, Gold DR
• Reply.
  Journal of Allergy and Clinical Immunology 2011 Ngoc P. Ly, Augusto Litonjua, Diane R. Gold, Juan C. Celedón
• Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity?
  The Journal of allergy and clinical immunology 2011 Ly NP, Litonjua A, Gold DR, Celedón JC
• Characterization of regulatory T cells in urban newborns.
  Clinical and molecular allergy : CMA 2009 Ly NP, Ruiz-Perez B, McLoughlin RM, Visness CM, Wallace PK, Cruikshank WW, Tzianabos AO, O'Connor GT, Gold DR, Gern JE
• Title: Relation Of Early Life Regulatory T-cell Function And Phenotype Development To Wheeze And Allergy: The Urban Environment And Childhood Asthma.
  Journal of Allergy and Clinical Immunology 2009 R.M. McLoughlin, N.P. Ly, C.M. Visness, P.K. Wallace, W.W. Cruikshank, B. Ruiz-Perez, J.E. Gern, D.R. Gold
• Dust mite exposure modifies the effect of functional IL10 polymorphisms on allergy and asthma exacerbations.
  The Journal of allergy and clinical immunology 2008 Hunninghake GM, Soto-Quirós ME, Lasky-Su J, Avila L, Ly NP, Liang C, Klanderman BJ, Raby BA, Gold DR, Weiss ST, Celedón JC
• Paternal asthma, mold exposure, and increased airway responsiveness among children with asthma in Costa Rica.
  Chest 2007 Ly NP, Soto-Quirós ME, Avila L, Hunninghake GM, Raby BA, Laskey D, Sylvia JS, Celedón JC
• Family history, environmental exposures in early life, and childhood asthma.
  The Journal of allergy and clinical immunology 2007 Ly NP, Celedón JC
• Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.
  The Journal of allergy and clinical immunology 2007 Hunninghake GM, Soto-Quirós ME, Avila L, Su J, Murphy A, Demeo DL, Ly NP, Liang C, Sylvia JS, Klanderman BJ, Lange C, Raby BA, Silverman EK, Celedón JC
• Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica.
  The Journal of allergy and clinical immunology 2007 Hunninghake GM, Soto-Quiros ME, Avila L, Ly NP, Liang C, Sylvia JS, Klanderman BJ, Silverman EK, Celedón JC
• Cord blood cytokines and acute lower respiratory illnesses in the first year of life.
  Pediatrics 2006 Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR
• Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age.
  The American journal of clinical nutrition 2006 Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR
• Mode of delivery and cord blood cytokines: a birth cohort study.
  Clinical and molecular allergy : CMA 2006 Ly NP, Ruiz-Pérez B, Onderdonk AB, Tzianabos AO, Litonjua AA, Liang C, Laskey D, Delaney ML, DuBois AM, Levy H, Gold DR, Ryan LM, Weiss ST, Celedón JC
• Recurrent wheeze in early childhood and asthma among children at risk for atopy.
  Pediatrics 2006 Ly NP, Gold DR, Weiss ST, Celedón JC
• Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma.
  The Journal of allergy and clinical immunology 2006 Gold DR, Willwerth BM, Tantisira KG, Finn PW, Schaub B, Perkins DL, Tzianabos A, Ly NP, Schroeter C, Gibbons F, Campos H, Oken E, Gillman MW, Palmer LJ, Ryan LM, Weiss ST
• Elevated allergen-induced IL-13 secretion predicts IgE elevation in children ages 2-5 years.
  Journal of clinical immunology 2005 Ly NP, Li Y, Sredl DL, Perkins DL, Finn PW, Weiss ST, Gold DR
• The protease inhibitor PI*S allele and COPD: a meta-analysis.
  The European respiratory journal 2005 Dahl M, Hersh CP, Ly NP, Berkey CS, Silverman EK, Nordestgaard BG
• Cytokines, allergy, and asthma.
  Current opinion in allergy and clinical immunology 2005 Ngoc PL, Ngoc LP, Gold DR, Tzianabos AO, Weiss ST, Celedón JC
• Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis.
  Thorax 2004 Hersh CP, Dahl M, Ly NP, Berkey CS, Nordestgaard BG, Silverman EK
• Allergen-induced cytokine production, atopic disease, IgE, and wheeze in children.
  The Journal of allergy and clinical immunology 2003 Contreras JP, Ly NP, Gold DR, He H, Wand M, Weiss ST, Perkins DL, Platts-Mills TA, Finn PW