Nathan Griffin, PhD
Postdoctoral Scholar
Cell and Tissue Biology
School of Dentistry

Education & Training

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• PhD Medical Biochemistry University of Newcastle 03/2021

Publications (19)

Top publication keywords:
Aquaporin 2Receptor, trkARutinReceptors, Nerve Growth FactorBiomarkers, TumorLipid MetabolismPeripheral NervesHead and Neck NeoplasmsEsophageal NeoplasmsNeoplasm InvasivenessNerve Growth FactorsNerve Growth FactorFluorocarbonsCaprylatesNerve Tissue Proteins

• The neurotrophic tyrosine kinase receptor 1 (TrkA) is overexpressed in oesophageal squamous cell carcinoma.
  Pathology 2020 Griffin N, Gao F, Jobling P, Oldmeadow C, Wills V, Walker MM, Faulkner S, Hondermarck H
• The Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer.
  Biomolecules 2020 Griffin N, Marsland M, Roselli S, Oldmeadow C, Attia J, Walker MM, Hondermarck H, Faulkner S
• Clinicopathological Significance of Nerves in Esophageal Cancer.
  The American journal of pathology 2020 Griffin N, Rowe CW, Gao F, Jobling P, Wills V, Walker MM, Faulkner S, Hondermarck H
• Targeting neurotrophin signaling in cancer: The renaissance.
  Pharmacological research 2018 Griffin N, Faulkner S, Jobling P, Hondermarck H
• Rescue of non-healing, degenerative salivary glands by cholinergic-calcium signaling.
  bioRxiv : the preprint server for biology 2025 Li J, Sun B, Tan LX, Griffin N, Niknezhad SV, Yu C, Berthoin L, Cruz-Pacheco N, Mohabbat S, Sinada H, Efraim Y, Chen FYT, An L, Gaylord EA, Bahney CS, Lombaert IMA, Knox SM

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• Perfluorooctanoic acid (PFOA) exposure induces renal filtration and reabsorption disorders via down-regulation of aquaporins.
  Toxicology letters 2023 Wang L, Sun W, Ma X, Griffin N, Liu H
• PFOA exposure induces aberrant glucose and lipid metabolism in the rat liver through the AMPK/mTOR pathway.
  Toxicology 2023 Zhang X, Ren X, Sun W, Griffin N, Wang L, Liu H
• Exposure to PFOA and its novel analogs disrupts lipid metabolism in zebrafish.
  Ecotoxicology and environmental safety 2023 Sun W, Zhang X, Qiao Y, Griffin N, Zhang H, Wang L, Liu H
• Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling.
  Developmental cell 2022 May AJ, Mattingly AJ, Gaylord EA, Griffin N, Sudiwala S, Cruz-Pacheco N, Emmerson E, Mohabbat S, Nathan S, Sinada H, Lombaert IMA, Knox SM
• Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism.
  Drug and chemical toxicology 2022 Ma X, Ren X, Zhang X, Griffin N, Liu H, Wang L
• iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction.
  Toxicology letters 2021 Liu H, Sun W, Zhou Y, Griffin N, Faulkner S, Wang L
• Interactions of perfluorooctanoic acid with acyl-CoA thioesterase 1 (Acot1).
  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2021 Liu H, Cheng J, Zhou Y, Liu F, Griffin N, Faulkner S, Wang L
• Tumor innervation and clinical outcome in pancreatic cancer.
  Scientific reports 2021 Ferdoushi A, Griffin N, Marsland M, Xu X, Faulkner S, Gao F, Liu H, King SJ, Denham JW, van Helden DF, Jobling P, Jiang CC, Hondermarck H
• Schwann Cell Stimulation of Pancreatic Cancer Cells: A Proteomic Analysis.
  Frontiers in oncology 2020 Ferdoushi A, Li X, Griffin N, Faulkner S, Jamaluddin MFB, Gao F, Jiang CC, van Helden DF, Tanwar PS, Jobling P, Hondermarck H
• Nerve growth factor and its receptor tyrosine kinase TrkA are overexpressed in cervical squamous cell carcinoma.
  FASEB bioAdvances 2020 Faulkner S, Griffin N, Rowe CW, Jobling P, Lombard JM, Oliveira SM, Walker MM, Hondermarck H
• The Membrane Protein Sortilin Can Be Targeted to Inhibit Pancreatic Cancer Cell Invasion.
  The American journal of pathology 2020 Gao F, Griffin N, Faulkner S, Li X, King SJ, Jobling P, Denham JW, Jiang CC, Hondermarck H
• Innervation of papillary thyroid cancer and its association with extra-thyroidal invasion.
  Scientific reports 2020 Rowe CW, Dill T, Griffin N, Jobling P, Faulkner S, Paul JW, King S, Smith R, Hondermarck H
• The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung.
  Scientific reports 2018 Gao F, Griffin N, Faulkner S, Rowe CW, Williams L, Roselli S, Thorne RF, Ferdoushi A, Jobling P, Walker MM, Hondermarck H
• Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells.
  Clinical epigenetics 2016 Sanders KA, Benton MC, Lea RA, Maltby VE, Agland S, Griffin N, Scott RJ, Tajouri L, Lechner-Scott J