Narges Alipanah-Lechner, MD, MAS
Assistant Professor
Medicine
School of Medicine

Dr. Alipanah-Lechner's research interest is to apply complementary systems biology approaches within precision medicine to improve the diagnosis and treatment of patients with syndromes of critical illness such as sepsis and ARDS. She currently attends in the intensive care units and the pulmonary function laboratory at UCSF.

• Treatment with Allogenic Mesenchymal Stromal Cells for Moderate to Severe Acute Respiratory Distress Syndrome: A Double-Blind, Placebo-controlled, Multi-Center, Phase 2b Clinical Trial (STAT).
  American journal of respiratory and critical care medicine 2025 Matthay MA, Zhou H, Sarma A, Alipanah-Lechner N, Hendrickson C, Kornblith LZ, Schreiber M, Zonies D, Khan A, Robinson B, Johnson NJ, Ware LB, Guillamondegui O, Casey J, Moore L, Patel B, Kao L, Wade …
• MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury.
  JCI insight 2025 Pickering H, Alipanah-Lechner N, Chen E, Duchen D, Maecker HT, Kim-Schulze S, Montgomery RR, Cotsapas C, Steen H, Krammer F, Langelier CR, Levy O, Baden LR, Melamed E, Ehrlich LI, McComsey GA, Sekaly …
• Awake Prone Positioning in COVID-19-Is There a New Standard of Care?
  JAMA internal medicine 2025 Matthay MA, Wick KD, Alipanah-Lechner N
• Gut bacterial lactate stimulates lung epithelial mitochondria and exacerbates acute lung injury.
  bioRxiv : the preprint server for biology 2025 Upadhyay V, Ortega EF, Ramirez Hernandez LA, Alexander M, Kaur G, Trepka K, Rock RR, Shima RT, Cheshire WC, Alipanah-Lechner N, Calfee CS, Matthay MA, Lee JV, Goga A, Jain IH, Turnbaugh PJ
• The Global Definition and the Future of ARDS Research.
  Respiratory care 2025 Burns GD, Alipanah-Lechner N, Daniel BM
• From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU.
  American journal of respiratory and critical care medicine 2024 Gordon AC, Alipanah-Lechner N, Bos LD, Dianti J, Diaz JV, Finfer S, Fujii T, Giamarellos-Bourboulis EJ, Goligher EC, Gong MN, Karakike E, Liu VX, Lumlertgul N, Marshall JC, Menon DK, Meyer NJ, Munroe …
• The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia.
  American journal of respiratory and critical care medicine 2024 Chouchane O, Schuurman AR, Reijnders TDY, Peters-Sengers H, Butler JM, Uhel F, Schultz MJ, Bonten MJ, Cremer OL, Calfee CS, Matthay MA, Langley RJ, Alipanah-Lechner N, Kingsmore SF, Rogers A, van …
• Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.
  Critical care (London, England) 2024 Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS, I-SPY COVID Consortium
• From Berlin to Global: The Need for Syndromic Definitions of Acute Respiratory Distress Syndrome.
  American journal of respiratory and critical care medicine 2024 Alipanah-Lechner N, Cavalcanti AB, Diaz J, Ferguson ND, Myatra SN, Calfee CS
• Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS.
  American journal of physiology. Lung cellular and molecular physiology 2023 Alipanah-Lechner N, Neyton L, Mick E, Willmore A, Leligdowicz A, Contrepois K, Jauregui A, Zhuo H, Hendrickson C, Gomez A, Sinha P, Kangelaris KN, Liu KD, Matthay MA, Rogers AJ, Calfee CS
• Interventions to enhance treatment adherence and retention in care for HIV-TB.
  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 Hudson M, Alipanah N, Singh S, Nahid P
• Phenotyping in acute respiratory distress syndrome: state of the art and clinical implications.
  Current opinion in critical care 2022 Alipanah N, Calfee CS
• Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: A retrospective cohort study of patients with and without COVID-19.
  EClinicalMedicine 2020 Shah SJ, Barish PN, Prasad PA, Kistler A, Neff N, Kamm J, Li LM, Chiu CY, Babik JM, Fang MC, Abe-Jones Y, Alipanah N, Alvarez FN, Botvinnik OB, Castaneda G, CZB CLIAhub Consortium, Dadasovich RM, …
• Summary for Clinicians: 2019 Clinical Practice Guideline Summary for the Treatment of Drug-Resistant Tuberculosis.
  Annals of the American Thoracic Society 2020 Berger CA, Alipanah N, Kheir F, Ruminjo JK, Nahid P, Thomson C
• Management and Outcomes of Critically-III Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series.
  medRxiv : the preprint server for health sciences 2020 Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, …
• Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: a comparison of patients with and without COVID-19.
  medRxiv : the preprint server for health sciences 2020 Shah SJ, Barish PN, Prasad PA, Kistler AL, Neff N, Kamm J, Li LM, Chiu CY, Babick JM, Fang MC, Abe-Jones Y, Alipanah N, Alvarez FN, Botvinnik OB, Davis JM, Castenada GD, Consortium C, Dadasovich RM, …
• Feasibility of Direct Sputum Molecular Testing for Drug Resistance as Part of Tuberculosis Clinical Trials Eligibility Screening.
  Diagnostics (Basel, Switzerland) 2019 Alipanah N, Shete PB, Nguyen H, Nguyen NV, Luu L, Pham T, Nguyen H, Nguyen P, Tran MC, Pham N, Phan H, Phillips PPJ, Cattamanchi A, Nahid P
• Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies.
  PLoS medicine 2018 Alipanah N, Jarlsberg L, Miller C, Linh NN, Falzon D, Jaramillo E, Nahid P
• Treatment of non-cavitary pulmonary tuberculosis with shortened fluoroquinolone-based regimens: a meta-analysis.
  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2016 Alipanah N, Cattamanchi A, Menzies R, Hopewell PC, Chaisson RE, Nahid P
• Executive Summary: Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, Chaisson LH, Chaisson RE, Daley CL, Grzemska M, Higashi JM, Ho CS, Hopewell PC, Keshavjee SA, Lienhardt C, Menzies R, Merrifield C, …
• Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, Chaisson LH, Chaisson RE, Daley CL, Grzemska M, Higashi JM, Ho CS, Hopewell PC, Keshavjee SA, Lienhardt C, Menzies R, Merrifield C, …
• Genitourinary exam skills training curriculum for medical students: a follow-up study of comfort and skill utilization.
  Journal of endourology 2012 Kaplan AG, Abdelshehid CS, Alipanah N, Zamansani T, Lee J, Kolla SB, Sountoulides PG, Graversen J, Lusch A, Kaufmann OG, Louie M, Clayman RV, McDougall EM
• Low serum carotenoids are associated with a decline in walking speed in older women.
  The journal of nutrition, health & aging 2009 Alipanah N, Varadhan R, Sun K, Ferrucci L, Fried LP, Semba RD
• Nontuberculous mycobacteria among patients who are suspected for multidrug-resistant tuberculosis-need for earlier identification of nontuberculosis mycobacteria.
  The American journal of the medical sciences 2009 Tabarsi P, Baghaei P, Farnia P, Mansouri N, Chitsaz E, Sheikholeslam F, Marjani M, Rouhani N, Mirsaeidi M, Alipanah N, Amiri M, Masjedi MR, Mansouri D
• Representative drug susceptibility patterns for guiding design of re-treatment regimens for multidrug-resistant tuberculosis in Iran.
  Respirology (Carlton, Vic.) 2008 Tabarsi P, Nooraki A, Mirsaeidi M, Amiri M, Baghaei P, Farnia P, Kazempour M, Heidarnazhad H, Alipanah N, Mansouri D, Masjedi MR
• Treatment outcome of tuberculosis patients diagnosed with human immunodeficiency virus infection in Iran.
  Saudi medical journal 2008 Tabarsi P, Baghaei P, Mirsaeidi M, Amiri M, Alipanah N, Emami H, Novin A, Mansouri D, Masjedi MR, Velayati AA