Nareg Roubinian, MD, MPH
Associate Professor
Laboratory Medicine
School of Medicine

Publications (130)

Top publication keywords:
Blood PreservationPlatelet TransfusionTransfusion ReactionPulmonary EmbolismBlood Component TransfusionAnemiaBlood DonorsHemoglobinsTransfusion MedicineHemolysisVenous ThromboembolismErythrocytesErythrocyte TransfusionTransfusion-Related Acute Lung InjuryBlood Transfusion

• Blood donor SARS-CoV-2 infection or vaccination and adverse outcomes in plasma and platelet transfusion recipients.
  Transfusion 2025 Roubinian NH, Greene J, Spencer BR, Bravo M, Bruhn R, Saa P, Stone M, Custer B, Kleinman S, Liu VX, Norris PJ, Busch MP, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV)
• Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes.
  Cell metabolism 2024 Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman ZB, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson …
• Donor genetic and nongenetic factors affecting red blood cell transfusion effectiveness.
  JCI insight 2022 Roubinian NH, Reese SE, Qiao H, Plimier C, Fang F, Page GP, Cable RG, Custer B, Gladwin MT, Goel R, Harris B, Hendrickson JE, Kanias T, Kleinman S, Mast AE, Sloan SR, Spencer BR, Spitalnik SL, Busch …
• Effect of donor, component, and recipient characteristics on hemoglobin increments following red blood cell transfusion.
  Blood 2019 Roubinian NH, Plimier C, Woo JP, Lee C, Bruhn R, Liu VX, Escobar GJ, Kleinman SH, Triulzi DJ, Murphy EL, Busch MP
• Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients.
  JAMA 2019 Edgren G, Murphy EL, Brambilla DJ, Westlake M, Rostgaard K, Lee C, Cable RG, Triulzi D, Bruhn R, St Lezin EM, Erikstrup C, Ullum H, Glynn SA, Kleinman S, Hjalgrim H, Roubinian NH, NHLBI Recipient …

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• Red Blood Cell Transfusion Characteristics and Morbidity or Mortality in Very-Low-Birth-Weight Infants.
  JAMA network open 2026 Hendrickson JE, Birch RJ, Rowley EAK, Sola-Visner M, Branchford BR, Chen X, Custer B, DeSimone RA, Bougie DW, Edwards EM, Goel R, Gottschall J, Hod EA, Moayeri M, Roubinian NH, Karam O, VanWormer JJ, …
• Antenatal Pulmonary Embolism Diagnostics in Pregnant Patients with SARS-CoV-2 Infection in Community Hospitals.
  TH open : companion journal to thrombosis and haemostasis 2026 Florio CJ, Heringer GV, Somers MJ, Qiao E, Zekar L, Middleton CE, Woldemariam ST, Gupta N, Poth LS, Reed ME, Sperling JD, Roubinian NH, Vinson DR
• Associations of blood donor and product characteristics with platelet transfusion outcomes.
  Blood advances 2026 Roubinian NH, Plimier C, Thomas KA, Spencer BR, Bravo M, Goel R, Baumann Kreuziger L, Hod EA, Custer B, Kleinman S, Norris PJ, Busch MP
• Improved red blood cell storage quality of blood from donors carrying the hypermorphic PIMT I120 variant.
  HemaSphere 2026 Bevers S, Issaian AV, Hay A, Keele GR, Dzieciatkowska M, Reisz JA, Haiman ZB, Nemkov T, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Palsson BO, Roubinian NH, …
• Lower efficacy of transfusion of red blood cells from donors with sickle cell trait.
  HemaSphere 2026 Dzieciatkowska M, Stephenson D, Hay A, Wang X, Keele GR, Nemkov T, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Spitalnik SL, Roubinian N, Zimring JC, Thein SL, D'Alessandro A
• Association Between Nasal Septal Deviation and Estimated Pulmonary Artery Pressures-Scoping Review.
  Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2026 Collazo SA, Ramirez KA, Roubinian NH, Vafaei P, Jiang N, Taylor CM
• A population-scale Red Blood Cell proteome atlas of 13,000 donors uncovers genetically encoded aging clocks predicting hemolysis, transfusion efficacy, and donor activity a decade later.
  bioRxiv : the preprint server for biology 2026 Dzieciatkowska M, Issaian AV, Keele GR, Saviola A, Stephenson D, Bevers S, Reisz JA, Haiman ZB, Nemkov T, Fang F, Moore AL, Deng X, Stone M, Kleinman S, Norris PJ, Wang X, Thein SL, Hod EA, Busch MP, …
• Weak Evidence, Rare Eligibility, and Complex Care Coordination Limit Application of Structured Surveillance for Subsegmental Pulmonary Embolism.
  Annals of emergency medicine 2026 Vinson DR, Rouleau SG, Balasubramanian MJ, Roubinian NH, Pai AP
• Transfusion requirements in recipients of plasma units from blood donors with recent SARS-CoV-2 infection.
  Transfusion 2026 Roubinian NH, Plimier C, Spencer BR, Bravo M, Custer B, D'Alessandro A, Kleinman S, Norris PJ, Busch MP, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV)
• Nationally representative estimates of health care burden of venous thromboembolism in hospitalized cancer patients.
  Research and practice in thrombosis and haemostasis 2026 Maiocco G, Streiff MB, Roubinian NH, Poston J, Bitner S, Hussain M, Khalid N, Jacobs JW, Bloch EM, Tobian AAR, Goel R
• Neonatal outcomes following maternal red cell transfusions prior to or at delivery.
  Journal of perinatology : official journal of the California Perinatal Association 2026 Hendrickson JE, Birch RJ, VanWormer JJ, Baumann Kreuziger L, McIntosh JJ, Reese SE, Josephson CD, Roubinian NH, Mast AE, Ness PM, Luban NLC, Spencer BR, Custer BS, Hod EA, Son M, McClure DL, DeSimone …
• Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice.
  HemaSphere 2026 Zimring JC, Hay AM, Dzieciatkowska M, Stephenson D, Haiman ZB, Kleinman S, Norris PJ, Busch MP, Roubinian N, Fermo E, Bianchi P, Keele GR, Page GP, D'Alessandro A
• Platelet Transfusion Practices and Outcomes in Neonates and Children.
  JAMA network open 2026 Goel R, Karam O, Warden DE, Birch RJ, Binns TC, Punzalan R, Roubinian N, Yurtsever N, Patel RM, Bougie D, Luban N, Josephson CD, Sola-Visner M, Nellis ME, NHLBI Recipient Epidemiology and Donor …
• International classification of diseases codes have low positive predictive value for neonatal morbidities.
  Journal of perinatology : official journal of the California Perinatal Association 2025 Hendrickson JE, Birch RJ, Sola-Visner MC, Branchford BR, Chen X, Custer BS, Desimone RA, Bougie DW, Edwards EM, Goel R, Gottschall J, Hod EA, Moayeri M, Roubinian NH, Karam O, Stone EF, Luban NLC, …
• Integrated analysis of blood donor metabolic phenotypes and genetic traits on red blood cell transfusion effectiveness.
  Blood. Red cells & iron 2025 Roubinian NH, Plimier C, Fang F, Page GP, Nemkov T, Kanias T, Custer B, Kleinman S, Norris PJ, Busch MP, D'Alessandro A
• Vein-To-Vein Databases: Uses and Considerations in Transfusion Research.
  Transfusion medicine reviews 2025 Lewin A, Rochette S, Shih AW, Tinmouth A, Chassé M, O'Brien SF, Busch MP, Roubinian NH, Erikstrup C, Dieudé M, Carrier FM, Callum J, Arnold DM, Canadian Transfusion Trials Group
• Genetic variation of human G6PD impacts Red Blood Cell transfusion efficacy.
  bioRxiv : the preprint server for biology 2025 Karafin MS, Issaian AV, Bevers S, Reisz JA, Hay A, Keele GR, Dzieciatkowska M, Cendali FI, Haiman ZB, Key AM, Nemkov T, Stephenson D, Marsh E, Moore AL, Palha MS, Legenzov EA, Lamb DR, Deng X, Stone M…
• Cost-effectiveness of a hypothetical assay to evaluate stored blood quality prior to transfusion.
  Vox sanguinis 2025 Caughey MC, Templin T, Roubinian NH, Karafin MS
• Strategies to Reduce Advanced Imaging in Antenatal Pulmonary Embolism Diagnostics.
  JAMA network open 2025 Vinson DR, Somers MJ, Zekar L, Qiao E, Middleton CE, Woldemariam ST, Gupta N, Poth LS, Reed ME, Sperling JD, Roubinian NH
• Transfusion thresholds and other strategies for guiding red blood cell transfusion.
  The Cochrane database of systematic reviews 2025 Carson JL, Stanworth SJ, Dennis JA, Fergusson DA, Pagano MB, Roubinian NH, Turgeon AF, Valentine S, Trivella M, Dorée C, Hébert PC
• Advanced Imaging in Suspected Antenatal Pulmonary Embolism in Community Practice: Preferences, Indeterminacy, and Clinician Response.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2025 Vinson DR, Somers MJ, Middleton CE, Zekar L, Qiao E, Woldemariam ST, Gupta N, Poth LS, Urbania TH, Niederkohr RD, Reed ME, Sperling JD, Roubinian NH
• GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells.
  Blood. Red cells & iron 2025 Stephenson D, Keele GR, Hay A, Dzieciatkowska M, Reisz JA, Haiman ZB, Moore AL, Nemkov T, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Churchill GA, Stockwell BR, Roubinian N, Zimring …
• Caffeine impairs red blood cell storage quality by dual inhibition of ADORA2b signaling and G6PD activity.
  Haematologica 2025 Dzieciatkowska M, Hay A, Issaian A, Keele GR, Bevers S, Nemkov T, Reisz JA, Maslanka M, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Roubinian N, Xia Y…
• Variation in effectiveness of blood transfusion by hospital day: A multicenter retrospective study.
  Journal of hospital medicine 2025 Bosch NA, Law AC, Roubinian NH, Reza Jafarzadeh S, Walkey AJ
• Donor genetics and storage conditions influence mitochondrial DNA and extracellular vesicle levels in RBC units.
  JCI insight 2025 Deng X, Di Germanio C, Marques de Menezes EG, Milani P, Stone M, Tanner H, Bakkour SC, Chafets DM, Reese SE, Roubinian NH, Kleinman S, Kanias T, Busch MP, Earley EJ, Page GP, Nemkov T, D'Alessandro A,…
• Caffeine Impairs Red Blood Cell Storage Quality by Dual Inhibition of ADORA2b Signaling and G6PD Activity.
  bioRxiv : the preprint server for biology 2025 Dzieciatkowska M, Hay A, Issaian A, Keele GR, Bevers S, Nemkov T, Reisz JA, Maslanka M, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Roubinian N, Xia Y…
• Corrigendum to 'Preemptive anticoagulation during antenatal pulmonary embolism diagnostics in a community setting: retrospective cohort study': [Research and Practice in Thrombosis and Haemostasis Volume 9, Issue 1, January 2025, 102695].
  Research and practice in thrombosis and haemostasis 2025 Campbell AR, Florio CJ, Heringer GV, Woldemariam ST, Casey SD, Stubblefield WB, Westafer LM, Qiao E, Middleton CE, Zekar L, Gupta N, Somers MJ, Reed ME, Roubinian NH, Pai AP, Sperling JD, Vinson DR
• The Red Blood Cell-Improving Transfusions for Chronically Transfused Recipients (RBC-IMPACT) study: protocol description of an international multi-site observational clinical study.
  Blood transfusion = Trasfusione del sangue 2025 Karafin MS, Kelly S, Chapman KM, Kreuziger LB, Manis JP, Dinardo C, Josephson CD, Stone M, Roubinian NH, Branchford B, Sachais BS, Hailu B, Sabino EC, Hod EA, Custer B, National Heart, Lung, and Blood…
• Patterns and Factors Associated With Preoperative Biopsy Among Patients With Non-Small Cell Lung Cancer in an Integrated Healthcare System.
  American Journal of Respiratory and Critical Care Medicine 2025 J. Bhattacharjee, V. Sarovar, S. Zhu, Z. Zhu, H.I. Tupper, N.H. Roubinian, R. Liu, C.P. Quesenberry, J.B. Velotta, L.C. Sakoda
• An agnostic study of donor and component factors associated with transfusion-related changes in laboratory markers.
  Transfusion 2025 Ekström LD, Clements M, Roubinian N, Zhao J, Dahlén T, Busch MP, Edgren G
• Ferroptosis regulates hemolysis in stored murine and human red blood cells.
  Blood 2025 D'Alessandro A, Keele GR, Hay A, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman S, Spitalnik SL, Roubinian N, Norris PJ, Busch MP, Page GP, …
• Preemptive anticoagulation during antenatal pulmonary embolism diagnostics in a community setting: retrospective cohort study.
  Research and practice in thrombosis and haemostasis 2025 Campbell AR, Florio CJ, Heringer GV, Woldemariam ST, Casey SD, Stubblefield WB, Westafer LM, Qiao E, Middleton CE, Zekar L, Gupta N, Somers MJ, Reed ME, Roubinian NH, Pai AP, Sperling JD, Vinson DR
• Red blood cell urate levels are linked to hemolysis in vitro and post-transfusion as a function of donor sex, population and genetic polymorphisms in SLC2A9 and ABCG2.
  Transfusion 2025 Key AM, Earley EJ, Tzounakas VL, Anastasiadi AT, Nemkov T, Stephenson D, Dzieciatkowska M, Reisz JA, Keele GR, Deng X, Stone M, Kleinman S, Hansen KC, Norris PJ, Busch MP, Roubinian NH, Page GP, D'…
• Optimizing RBC Transfusion Management in Patients on Venovenous Extracorporeal Membrane Oxygenation.
  Chest 2024 Roubinian NH, Ha R
• Consent to advanced imaging in antenatal pulmonary embolism diagnostics: Prevalence, outcomes of nonconsent and opportunities to mitigate delayed diagnosis risk.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2024 Vinson DR, Somers MJ, Qiao E, Campbell AR, Heringer GV, Florio CJ, Zekar L, Middleton CE, Woldemariam ST, Gupta N, Poth LS, Reed ME, Roubinian NH, Raja AS, Sperling JD
• Arginine Metabolism Is a Biomarker of Red Blood Cell and Human Aging.
  Blood 2024 Julie A Reisz Haines, Eric Earley, Travis Nemkov, Alicia Key, Daniel Stephenson, Gregory R Keele, Monika Dzieciatkowska, Steven L Spitalnik, Eldad A. Hod, Steven Kleinman, Nareg Roubinian, Mark …
• Arginine metabolism is a biomarker of red blood cell and human aging.
  Aging cell 2024 Reisz JA, Earley EJ, Nemkov T, Key A, Stephenson D, Keele GR, Dzieciatkowska M, Spitalnik SL, Hod EA, Kleinman S, Roubinian NH, Gladwin MT, Hansen KC, Norris PJ, Busch MP, Zimring JC, Churchill GA, …
• Genetic determinants of plasma testosterone in male blood donors are associated with altered red blood cell characteristics and survival in cold storage and after transfusion.
  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2024 Fang F, Roubinian NH, Bean SW, Kemmler C, Page GG, Kanias T
• 173 Radiation-Reducing Strategies in Antenatal Pulmonary Embolism Diagnostics: Differences in Testing Efficiency and Specialty-Specific Use Patterns.
  Annals of Emergency Medicine 2024 C. Middleton, L. Zekar, S. Woldemariam, E. Qiao, M. Somers, N. Gupta, L. Poth, J. Sperling, N. Roubinian, D. Vinson
• 282 Prevalence, Characteristics, and Outcomes of Patients Who Decline Pulmonary Vascular Imaging During Antenatal Pulmonary Embolism Diagnostics.
  Annals of Emergency Medicine 2024 E. Qiao, A. Campbell, G. Heringer, C. Florio, J. Sperling, N. Roubinian, D. Vinson
• The prevalence of hepatitis B virus, human T-lymphotropic virus and human immunodeficiency virus in patients receiving blood transfusions in South Africa.
  Vox sanguinis 2024 Willemse RJ, Grobler CJ, Murphy EL, Roubinian N, Colemen C, Machaba S, Vermeulen M
• Expanding outpatient management of low-risk pulmonary embolism to the pregnant population: a case series.
  European heart journal. Case reports 2024 Vinson DR, Roubinian NH, Pai AP, Sperling JD
• Testosterone supplementation increases red blood cell susceptibility to oxidative stress, decreases membrane deformability, and decreases survival after cold storage and transfusion.
  Transfusion 2024 Tran J, Jackman RP, Muench MO, Hazegh K, Bean SW, Thomas KA, Fang F, Page G, O'Connor K, Roubinian NH, Anawalt BD, Kanias T
• Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
  Blood 2024 Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA,…
• Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes.
  bioRxiv : the preprint server for biology 2024 Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman Z, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson …
• Ferroptosis regulates hemolysis in stored murine and human red blood cells.
  bioRxiv : the preprint server for biology 2024 D'Alessandro A, Keele GR, Hay A, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman S, Spitalnik SL, Roubinian NH, Norris PJ, Busch MP, Page GP, …
• Video-Assisted vs Robotic-Assisted Lung Lobectomies for Operating Room Resource Utilization and Patient Outcomes.
  JAMA network open 2024 Tupper HI, Lawson BL, Kipnis P, Patel AR, Ashiku SK, Roubinian NH, Myers LC, Liu VX, Velotta JB
• Hospital-associated venous thromboembolism prophylaxis use by risk assessment at a large integrated health care network in Northern California.
  Journal of hospital medicine 2024 Xu J, Neeman E, Thai KK, Mishra P, Schlessinger D, Clancy H, Myers L, Roubinian N, Liu V, Liu R
• Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.
  Blood 2024 Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'…
• Clinical outcomes in hospitalized plasma and platelet transfusion recipients prior to and following widespread blood donor SARS-CoV-2 infection and vaccination.
  Transfusion 2023 Roubinian NH, Greene J, Liu VX, Lee C, Mark DG, Vinson DR, Spencer BR, Bruhn R, Bravo M, Stone M, Custer B, Kleinman S, Busch MP, Norris PJ, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-…
• Co-Diagnosis of Sickle Cell and Chronic Myelogenous Leukemia: Exploratory Analysis from a Nationally Representative Database.
  Blood 2023 Giuseppe Maiocco, Ruchika Goel, Waqas Azhar, Ejaz Shah, Mohammad Junaid Hussain, Nareg Roubinian, Cassandra Josephson, Ross M. Fasano, Morgan L. McLemore
• Selected Topics From the State of the Science in Transfusion Medicine: Key Insights on Current Progress and Future Directions.
  Transfusion medicine reviews 2023 Roubinian NH, Custer B
• Blood Demand Forecasting and Supply Management: An Analytical Assessment of Key Studies Utilizing Novel Computational Techniques.
  Transfusion medicine reviews 2023 Li N, Pham T, Cheng C, McElfresh DC, Metcalf RA, Russell WA, Birch R, Yurkovich JT, Montemayor-Garcia C, Lane WJ, Tobian AAR, Roubinian N, Seheult J, Goel R
• OA1-AM23-MN-23 | Clinical Outcomes in Hospitalized Plasma and Platelet Transfusion Recipients Prior to and Following Periods of Blood Donor SARS-CoV-2 Infection and Vaccination.
  Transfusion 2023 N. Roubinian, J. Greene, V. Liu, D. Mark, M. Stone, B. Spencer, S. Kleinman, M. Busch, P. Norris
• OA2-AM23-MN-23 | Metabolomics Analysis of Over 13,000 Donors From the REDS RBC Omics Study Identifies Markers of Hemolysis and In Vivo Hemoglobin Increments.
  Transfusion 2023 T. Nemkov, D. Stephenson, N. Roubinian, C. Erickson, M. Stone, X. Deng, S. Kleinman, M. Busch, P. Norris, A. D'Alessandro
• Associations of donor, component, and recipient factors on hemoglobin increments following red blood cell transfusion in very low birth weight infants.
  Transfusion 2023 DeSimone RA, Plimier C, Goel R, Hendrickson JE, Josephson CD, Patel RM, Sola-Visner M, Roubinian NH
• Letter to the editor: "Clinical controversies in the management of acute pulmonary embolism".
  Expert review of respiratory medicine 2023 Casey SD, Rouleau SG, Vinson DR, Roubinian NH
• The impact of timing of initiating invasive mechanical ventilation in COVID-19-related respiratory failure.
  Journal of critical care 2023 Myers LC, Kipnis P, Greene JD, Chen A, Creekmur B, Xu S, Sankar V, Roubinian NH, Langer-Gould A, Gould MK, Liu VX
• Acute myocardial infarction and blood transfusion: lessons learned from animal models and clinical studies.
  Blood transfusion = Trasfusione del sangue 2023 Roubinian NH, Carson JL
• Disentangling the causes of RBC loss and anemia in ECMO patients: Some questions answered?
  Transfusion 2023 Goel R, Roubinian NH, Bembea MM
• Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium.
  Transfusion 2023 Custer B, Bloch EM, Bryant BJ, D'Alessandro A, Delaney M, Goel R, Hod EA, Josephson CD, Katz LM, Miller YM, Sayers MH, Seheult JN, Triulzi DJ, Berger J, Zou S, Hailu B, Glynn SA, Roubinian NH
• Associations between ABO non-identical platelet transfusions and patient outcomes-A multicenter retrospective analysis.
  Transfusion 2023 Bougie DW, Reese SE, Birch RJ, Bookwalter DB, Mitchell PK, Roh D, Kreuziger LB, Cable RG, Goel R, Gottschall J, Hauser RG, Hendrickson JE, Hod EA, Josephson CD, Kahn S, Kleinman SH, Mast AE, Ness PM, …
• Blood donor, component, and recipient-specific factors associated with venous thromboembolism in transfused hospitalized adult patients: Data from the recipient epidemiology and donor evaluation Study-III (REDS-III).
  Transfusion 2023 Goel R, Plimier C, Lee C, Tobian AAR, Josephson CD, Hod EA, Roubinian NH
• Review of Pulmonary Embolism.
  JAMA 2023 Vinson DR, Sperling JD, Roubinian NH
• Risk of VTE in Nonrespiratory and Respiratory Presentations of COVID-19 in Critically Ill Patients.
  Chest 2023 Roubinian NH, Vinson DR, Pai AP, Myers LC, Skarbinski J, Lee C, Mark DG, Liu VX
• Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status.
  Blood advances 2023 Roubinian NH, Vinson DR, Knudson-Fitzpatrick T, Mark DG, Skarbinski J, Lee C, Liu VX, Pai AP
• Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection.
  Viruses 2022 van den Berg K, Vermeulen M, Bakkour S, Stone M, Jacobs G, Nyoni C, Barker C, McClure C, Creel D, Grebe E, Roubinian N, Jentsch U, Custer B, Busch MP, Murphy EL
• Association between anaemia and hospital readmissions in patients undergoing major surgery requiring postoperative intensive care.
  Anaesthesia 2022 Warner MA, Hanson AC, Plimier C, Lee C, Liu VX, Richards T, Kor DJ, Roubinian NH
• Red Blood Cell Transfusion at a Hemoglobin Threshold of 7 g/dl in Critically Ill Patients: A Regression Discontinuity Study.
  Annals of the American Thoracic Society 2022 Bosch NA, Law AC, Bor J, Myers LC, Roubinian NH, Liu VX, Walkey AJ
• Early Post-Hospitalization Hemoglobin Recovery and Clinical Outcomes in Survivors of Critical Illness: A Population-Based Cohort Study.
  Journal of intensive care medicine 2022 Warner MA, Hanson AC, Schulte PJ, Roubinian NH, Storlie C, Demuth G, Gajic O, Kor DJ
• Transfusion thresholds for guiding red blood cell transfusion.
  The Cochrane database of systematic reviews 2021 Carson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, Triulzi D, Dorée C, Hébert PC
• Incidence of 30-Day Venous Thromboembolism in Adults Tested for SARS-CoV-2 Infection in an Integrated Health Care System in Northern California.
  JAMA internal medicine 2021 Roubinian NH, Dusendang JR, Mark DG, Vinson DR, Liu VX, Schmittdiel JA, Pai AP
• Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress.
  Transfusion 2020 Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, D'Alessandro A, Dumont L, Page GP, Kanias T
• NT-proBNP levels in the identification and classification of pulmonary transfusion reactions.
  Transfusion 2020 Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (…
• Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers.
  Transfusion 2020 Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A, Recipient Epidemiology and Donor Evaluation Study-III (REDS …
• Additive effects of blood donor smoking and gamma irradiation on outcome measures of red blood cell transfusion.
  Transfusion 2020 DeSimone RA, Plimier C, Lee C, Kanias T, Cushing MM, Sachais BS, Kleinman S, Busch MP, Roubinian NH
• The evanescence and persistence of RBC alloantibodies in blood donors.
  Transfusion 2020 Hauser RG, Esserman D, Karafin MS, Tan S, Balbuena-Merle R, Spencer BR, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Gottschall JL, Hendrickson JE, Tormey CA, (for the NHLBI Recipient Epidemiology and …
• Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting.
  Transfusion 2020 Bloch EM, Hull J, Green-Thompson R, Ingram C, Crookes RL, Fawcus S, Anthony J, Courtney L, Roubinian N, Jauregui A, Hilton JF, Murphy EL, NHLBI REDS-III South Africa Program
• Equivalent inpatient mortality among direct-acting oral anticoagulant and warfarin users presenting with major hemorrhage.
  Thrombosis research 2019 Bialkowski W, Tan S, Mast AE, Kiss JE, Kor D, Gottschall J, Wu Y, Roubinian N, Triulzi D, Kleinman S, Choi Y, Brambilla D, Zimrin A, NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study
• The Presence and Persistence of Pregnancy-Associated Red Blood Cell Alloantibodies in Blood Donors.
  Blood 2019 Raisa Balbuena-Merle, Ronald G. Hauser, Matthew Karafin, Sylvia Tan, Bryan R Spencer, Nareg Roubinian, Yanyun Wu, Darrell Triulzi, Steven Kleinman, Jerry Gottschall, Christopher A. Tormey, Jeanne E. …
• Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients.
  Transfusion 2019 Roubinian NH, Westlake M, St Lezin EM, Edgren G, Brambilla DJ, Lee C, Bruhn R, Cable RG, Triulzi DJ, Glynn SA, Kleinman S, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-…
• Methodological considerations for linked blood donor-component-recipient analyses in transfusion medicine research.
  ISBT science series 2019 Roubinian N, Kleinman S, Murphy EL, Glynn SA, Edgren G
• Blood donor component-recipient linkages: is there fire where there is smoke?
  Transfusion 2019 Roubinian NH, Kanias T
• Transfusion-Associated Circulatory Overload and Transfusion-Related Acute Lung Injury: Etiology and Prevention.
  Hematology/oncology clinics of North America 2019 Roubinian NH, Triulzi DJ
• Discovery of False Elite Controllers: HIV Antibody-Positive RNA-Negative Blood Donors Found To Be on Antiretroviral Therapy.
  The Journal of infectious diseases 2019 Sykes W, Van den Berg K, Jacobs G, Jauregui A, Roubinian N, Wiesner L, Maartens G, Swanevelder R, Custer B, Busch M, Jentsch U, Murphy EL, Vermeulen M, NHLBI Recipient Epidemiology and Donor …
• The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases.
  Transfusion 2019 Karafin MS, Bruhn R, Roubinian NH, Chowdhury D, Qu L, Snyder EL, Murphy EL, Brambilla D, Cable RG, Hilton JF, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study
• Red blood cell transfusions for emergency department patients with gastrointestinal bleeding within an integrated health system.
  The American journal of emergency medicine 2019 Mark DG, Huang J, Plimier C, Reed ME, Escobar GJ, Vinson DR, Roubinian NH
• Building consensus: steps toward standardised haemovigilance reporting.
  The Lancet. Haematology 2019 Roubinian N, Kleinman S
• Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients.
  Transfusion 2019 Norris PJ, Schechtman K, Inglis HC, Adelman A, Heitman JW, Vilardi R, Shah A, Roubinian NH, Danesh A, Guiltinan AM, Keating SM, Lacroix J, Cohen MJ, Spinella PC
• Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study.
  Annals of internal medicine 2018 Roubinian NH, Murphy EL, Mark DG, Triulzi DJ, Carson JL, Lee C, Kipnis P, Kleinman S, Liu VX, Escobar GJ
• TACO and TRALI: biology, risk factors, and prevention strategies.
  Hematology. American Society of Hematology. Education Program 2018 Roubinian N
• Inpatient Mortality and Length of Stay Among Direct-Acting Oral Anticoagulant (DOAC) and Warfarin Users Presenting with Major Hemorrhage.
  Blood 2018 Walter Bialkowski, Sylvia Tan, Alan E. Mast, Joseph Kiss, Daryl J. Kor, Jerome Gottschall, Yanyun Wu, Nareg H. Roubinian, Darrell Triulzi, Steven Kleinman, Young Choi, Donald Brambilla, Ann Butler …
• Prevalence and risk factors for RBC alloantibodies in blood donors in the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III).
  Transfusion 2018 Karafin MS, Tan S, Tormey CA, Spencer BR, Hauser RG, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Gottschall JL, Hendrickson JE
• Risk factors for red blood cell alloimmunization in the Recipient Epidemiology and Donor Evaluation Study (REDS-III) database.
  British journal of haematology 2018 Karafin MS, Westlake M, Hauser RG, Tormey CA, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Hendrickson JE, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III)
• Clinical trials evaluating red blood cell transfusion thresholds: An updated systematic review and with additional focus on patients with cardiovascular disease.
  American heart journal 2018 Carson JL, Stanworth SJ, Alexander JH, Roubinian N, Fergusson DA, Triulzi DJ, Goodman SG, Rao SV, Doree C, Hebert PC
• Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload.
  Critical care medicine 2018 Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Michalkiewicz M, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL, National Heart, Lung, and Blood Institute (…
• A multicentre study investigating vital sign changes occurring in complicated and uncomplicated transfusions.
  Vox sanguinis 2017 Gehrie EA, Roubinian NH, Chowdhury D, Brambilla DJ, Murphy EL, Gottschall JL, Wu Y, Ness PM, Strauss RG, Hendrickson JE, NHLBI Recipient Epidemiology-Donor Evaluation Study (REDS-III)
• Demographic and epidemiologic characterization of transfusion recipients from four US regions: evidence from the REDS-III recipient database.
  Transfusion 2017 Karafin MS, Bruhn R, Westlake M, Sullivan MT, Bialkowski W, Edgren G, Roubinian NH, Hauser RG, Kor DJ, Fleischmann D, Gottschall JL, Murphy EL, Triulzi DJ, National Heart, Lung, and Blood Institute …
• Statistical Caution in Big Data Approaches to Transfusion Medicine Research.
  JAMA internal medicine 2017 Roubinian N, Brambilla D, Murphy EL
• Differentiating pulmonary transfusion reactions using recipient and transfusion factors.
  Transfusion 2017 Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL, TRALI Study Group
• Adjusting the Focus on Transfusion-associated Circulatory Overload.
  Anesthesiology 2017 Roubinian N, Murphy EL
• OA04.06 Examining Pleiotropic Associations of Genetic Risk Variants for Chronic Obstructive Pulmonary Disease with Lung Cancer Risk.
  Journal of Thoracic Oncology 2017 Lori Sakoda, Khanh Thai, Nareg Roubinian, Carlos Iribarren, Catherine Schaefer, Neil Risch, Laurel Habel, Charles Quesenberry, Eric Jorgenson
• Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm.
  Vox sanguinis 2016 Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (…
• Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion.
  The Cochrane database of systematic reviews 2016 Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC
• Incidence of transfusion reactions: a multicenter study utilizing systematic active surveillance and expert adjudication.
  Transfusion 2016 Hendrickson JE, Roubinian NH, Chowdhury D, Brambilla D, Murphy EL, Wu Y, Ness PM, Gehrie EA, Snyder EL, George Hauser R, Gottschall JL, Kleinman S, Kakaiya R, Strauss RG, National Heart, Lung, and …
• Red Blood Cell Transfusion Strategies in Adult and Pediatric Patients with Malignancy.
  Hematology/oncology clinics of North America 2016 Roubinian N, Carson JL
• 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.
  Transfusion 2015 Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S, State of the Science in Transfusion Medicine …
• Restrictive red blood cell transfusion strategies appear safe in most clinical settings.
  Evidence-based medicine 2015 Roubinian NH, Carson JL
• Transfusion-associated circulatory overload (TACO): prevention, management, and patient outcomes.
  International Journal of Clinical Transfusion Medicine 2015 Edward Murphy, Nareg Roubinian
• Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions.
  Transfusion 2015 Roubinian NH, Looney MR, Kor DJ, Lowell CA, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson GA, Matthay MA, Toy P, Murphy EL, TRALI Study Group
• Shedding a little light on posttransfusion purpura.
  Transfusion 2015 Roubinian NH, Leavitt AD
• A multicenter study of plasma use in the United States.
  Transfusion 2014 Triulzi D, Gottschall J, Murphy E, Wu Y, Ness P, Kor D, Roubinian N, Fleischmann D, Chowdhury D, Brambilla D, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III)
• Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.
  Transfusion 2014 Roubinian NH, Escobar GJ, Liu V, Swain BE, Gardner MN, Kipnis P, Triulzi DJ, Gottschall JL, Wu Y, Carson JL, Kleinman SH, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III)
• Decreased red blood cell use and mortality in hospitalized patients.
  JAMA internal medicine 2014 Roubinian NH, Escobar GJ, Liu V, Gardner MN, Carson JL, Kleinman SH, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III)
• Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*.
  Critical care medicine 2014 Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, …
• Predicting red blood cell transfusion in hospitalized patients: role of hemoglobin level, comorbidities, and illness severity.
  BMC health services research 2014 Roubinian NH, Murphy EL, Swain BE, Gardner MN, Liu V, Escobar GJ, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III), Northern California Kaiser Permanente DOR Systems Research …
• Response.
  Chest 2013 Roubinian N, Blanc PD, Chen H
• Effects of commercial air travel on patients with pulmonary hypertension air travel and pulmonary hypertension.
  Chest 2012 Roubinian N, Elliott CG, Barnett CF, Blanc PD, Chen J, De Marco T, Chen H
• Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis.
  Transplant infectious disease : an official journal of the Transplantation Society 2012 Wiita AP, Roubinian N, Khan Y, Chin-Hong PV, Singer JP, Golden JA, Miller S
• A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America.
  PloS one 2010 Greninger AL, Chen EC, Sittler T, Scheinerman A, Roubinian N, Yu G, Kim E, Pillai DR, Guyard C, Mazzulli T, Isa P, Arias CF, Hackett J, Schochetman G, Miller S, Tang P, Chiu CY
• Treatment-related risk factors for hospital mortality in Candida bloodstream infections.
  Critical care medicine 2008 Labelle AJ, Micek ST, Roubinian N, Kollef MH
• Health care-associated pneumonia and community-acquired pneumonia: a single-center experience.
  Antimicrobial agents and chemotherapy 2007 Micek ST, Kollef KE, Reichley RM, Roubinian N, Kollef MH
• Before-after study of a standardized hospital order set for the management of septic shock.
  Critical care medicine 2006 Micek ST, Roubinian N, Heuring T, Bode M, Williams J, Harrison C, Murphy T, Prentice D, Ruoff BE, Kollef MH
• IMPLEMENTATION OF AN EARLY GOAL-DIRECTED SEPSIS PROTOCOL IN AN ACADEMIC EMERGENCY DEPARTMENT.
  Critical Care Medicine 2005 Nareg Roubinian, Donna Prentice, Marin Kollef, Tim Heuring, Meghan Bode, Theresa Murphy, Scott Micek, Jennifer Williams, Courtney Harrison
• Neisseria meningitidis endotoxin and capsule transmission by transplantation.
  Emerging infectious diseases 2005 Roubinian N, Kirkpatrick BD, Lynn F, Zenilman J, Bash M