Nancy Allen, MD, PhD
Assistant Professor
Medicine
School of Medicine

Awards

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• Bakar Aging Research Institute Postdoctoral Fellowship, UCSF, 2023
• Nina Ireland Program for Lung Health Innovative Grant, UCSF, 2023
• ABIM Certification in Critical Care Medicine, 2022
• ABIM Certification in Pulmonology, 2021
• ABIM Certification in Internal Medicine, 2019

Education & Training

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• Fellow Pulmonary and Critical Care Medicine University of California - San Francisco 2023
• Resident Internal Medicine University of California - San Francisco 2018
• Intern Internal Medicine University of California - San Francisco 2017
• MD Yale University School of Medicine 2016
• PhD Immunobiology Yale University 2015
• B.S. Molecular, Cell, and Developmental Biology University of California - Los Angeles 2005

Grants and Projects

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• Role of stromal inflammatory signaling in the aging of lung resident lymphocytes, NHLBI, 2023
• Mesenchymal inflammatory signaling in regulation of the immune response and tissue dysfunction during lipopolysaccharide-induced acute lung injury, NHLBI, 2022-2023

Publications (8)

Top publication keywords:
Cellular SenescenceLipopolysaccharidesBasic-Leucine Zipper Transcription FactorsCyclin-Dependent Kinase Inhibitor p16MacrophagesInterleukin-12 Subunit p40Pulmonary EmphysemaFibroblastsRegenerationBiological ClocksPulmonary Disease, Chronic ObstructiveGenes, ReporterStem Cell NicheEmphysemaCapillary Permeability

• Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir.
  Immunity 2023 Wang C, Hyams B, Allen NC, Cautivo K, Monahan K, Zhou M, Dahlgren MW, Lizama CO, Matthay M, Wolters P, Molofsky AB, Peng T
• Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung.
  Science (New York, N.Y.) 2022 Reyes NS, Krasilnikov M, Allen NC, Lee JY, Hyams B, Zhou M, Ravishankar S, Cassandras M, Wang C, Khan I, Matatia P, Johmura Y, Molofsky A, Matthay M, Nakanishi M, Sheppard D, Campisi J, Peng T
• Intersection of Inflammation and Senescence in the Aging Lung Stem Cell Niche.
  Frontiers in cell and developmental biology 2022 Allen NC, Reyes NS, Lee JY, Peng T
• Desynchronization of the molecular clock contributes to the heterogeneity of the inflammatory response.
  Science signaling 2019 Allen NC, Philip NH, Hui L, Zhou X, Franklin RA, Kong Y, Medzhitov R
• Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation.
  Cell 2014 Goddard LM, Murphy TJ, Org T, Enciso JM, Hashimoto-Partyka MK, Warren CM, Domigan CK, McDonald AI, He H, Sanchez LA, Allen NC, Orsenigo F, Chao LC, Dejana E, Tontonoz P, Mikkola HK, Iruela-Arispe ML
• A primary cilia-dependent etiology for midline facial disorders.
  Human molecular genetics 2010 Brugmann SA, Allen NC, James AW, Mekonnen Z, Madan E, Helms JA
• A dermal HOX transcriptional program regulates site-specific epidermal fate.
  Genes & development 2008 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY
• Skeletogenesis in the swell shark Cephaloscyllium ventriosum.
  Journal of anatomy 2007 Eames BF, Allen N, Young J, Kaplan A, Helms JA, Schneider RA