Nalin Gupta, MD, PhD
Professor
Neurological Surgery
School of Medicine
Nalin Gupta is Chief of the Division of Pediatric Neurosurgery at UCSF, and a Professor in the Departments of Neurological Surgery and Pediatrics. His clinical and research interests are directed towards neuro-oncology and congenital anomalies. He was the lead neurosurgeon at UCSF for a randomized clinical trials examining the effectiveness of fetal surgery for myelomeningocele.
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He also participated in a phase I clinical study examining the safety of stem cell transplantation for a disorder of myelination in humans. He is currently clinical PI of a phase I study examining the safety of gene therapy for children with primary AADC deficiency.
Education & Training
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- Pediatric Neurosurgery Hospital for Sick Children 06/1998
- Neurosurgery University of Toronto 06/1997
- Ph.D. Biophysics University of California San Francisco 05/1996
- M.D. School of Medicine University of Toronto 06/1987
- Biology McGill University 05/1983
Interests
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- Fetal surgery
- Brain tumors
- Tumor associated inflammation
- Early phase clinical trials
Websites
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- Profile at UCSF Neurosurgery (neurosurgery.ucsf.edu)
- Clinical Profile at UCSF Benioff Children's Hospital (ucsfbenioffchildrens.org)
Grants and Projects
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- Myeloid cells and radiation-induced memory deficits in rodent glioma model: sex and age effects, NIH, 2020-2025
- Use of a Long Non-coding RNA (lncRNA) as a Therapeutic Target in DIPG, Michael Mosier Defeat DIPG Foundation, 2019-2021
- Convection-enhanced delivery of nanoliposomal CPT-11 for the treatment of newly diagnosed children with diffuse intrinsic pontine glioma (DIPG), V Foundation, 2016-2019
- Macrophage and Microglial Activation in Glioma-Associated Inflammation, NIH, 2006-2011
Publications (162)
Top publication keywords:
Brain Stem NeoplasmsGliomaPonsNeurosurgical ProceduresCerebellar NeoplasmsMedulloblastomaMeningomyeloceleBrain NeoplasmsAstrocytomaPelizaeus-Merzbacher DiseaseCraniopharyngiomaIntracranial Arteriovenous MalformationsHydrocephalusSpinal Cord NeoplasmsEpendymoma
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Immunohistochemical Surrogates for Molecular Stratification in Medulloblastoma.
Applied immunohistochemistry & molecular morphology : AIMM 2023 Chinnam D, Saraswati A, Jogunoori S, Verma A, Kiran T, Salunke P, Gupta N, Kumar N, Madan R, Radotra BD, Gupta K -
Lymphoreticular malignancies in serous effusions: Cytomorphologic, flow cytometric and immunocytochemical analysis.
Diagnostic cytopathology 2021 Gupta P, Pandey T, Gautam U, Rajwanshi A, Srinivasan R, Gupta N, Rohilla M, Varma N, Dey P -
Small Cell Carcinoma of the Ovary: Clinicopathologic and Immunohistochemical Analysis of 7 New Cases of a Rare Malignancy.
International journal of surgical pathology 2020 Gupta P, Kapatia G, Gupta N, Dey P, Rohilla M, Gupta A, Rai B, Suri V, Rajwanshi A, Srinivasan R -
Role of bronchoalveolar lavage in diagnosing pulmonary infections and malignancies: Experience from a tertiary care center.
Diagnostic cytopathology 2020 Zaidi A, Kaur H, Gupta P, Gupta N, Srinivasan R, Dey P, Rohilla M, Rajwanshi A, Bal A, Agarwal R -
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.
Genome biology 2020 Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, …
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Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas.
Acta neuropathologica 2019 Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, … -
Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease.
Stem cell reports 2019 Gupta N, Henry RG, Kang SM, Strober J, Lim DA, Ryan T, Perry R, Farrell J, Ulman M, Rajalingam R, Gage A, Huhn SL, Barkovich AJ, Rowitch DH -
Cytopathological spectrum of peripheral neuroblastic tumours in fine needle aspiration cytology and categorisation as per International Neuroblastoma Pathology Classification.
Cytopathology : official journal of the British Society for Clinical Cytology 2019 Koshy A, Jain R, Srinivasan R, Bhatia P, Kakkar N, Rajwanshi A, Gupta N, Dey P, Trehan A, Bansal D -
Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma.
Acta neuropathologica 2019 Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan… -
Superficial temporal artery-to-middle cerebral artery bypass in combination with indirect revascularization in moyamoya patients ≤ 3 years of age.
Journal of neurosurgery. Pediatrics 2018 Bot GM, Burkhardt JK, Gupta N, Lawton MT -
Rescue of cognitive function following fractionated brain irradiation in a novel preclinical glioma model.
eLife 2018 Feng X, Liu S, Chen D, Rosi S, Gupta N -
The genetic landscape of anaplastic pleomorphic xanthoastrocytoma.
Brain pathology (Zurich, Switzerland) 2018 Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh … -
Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features.
Journal of neurosurgery. Pediatrics 2018 Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, Gupta N -
Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Panditharatna E, Kilburn LB, Aboian MS, Kambhampati M, Gordish-Dressman H, Magge SN, Gupta N, Myseros JS, Hwang EI, Kline C, Crawford JR, Warren KE, Cha S, Liang WS, Berens ME, Packer RJ, Resnick AC, … -
Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
Neuro-oncology 2018 Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z,… -
Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience.
Journal of neuro-oncology 2018 Kline C, Liu SJ, Duriseti S, Banerjee A, Nicolaides T, Raber S, Gupta N, Haas-Kogan D, Braunstein S, Mueller S -
The genetic landscape of gliomas arising after therapeutic radiation.
Acta neuropathologica 2018 López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C… -
Complications following pediatric cranioplasty after decompressive craniectomy: a multicenter retrospective study.
Journal of neurosurgery. Pediatrics 2018 Rocque BG, Agee BS, Thompson EM, Piedra M, Baird LC, Selden NR, Greene S, Deibert CP, Hankinson TC, Lew SM, Iskandar BJ, Bragg TM, Frim D, Grant G, Gupta N, Auguste KI, Nikas DC, Vassilyadi M, Muh CR,… -
The genetic landscape of ganglioglioma.
Acta neuropathologica communications 2018 Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney … -
Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
Acta neuropathologica 2018 Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, … -
The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes.
American journal of obstetrics and gynecology 2017 Farmer DL, Thom EA, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Gupta N, Adzick NS, Management of Myelomeningocele Study Investigators -
New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model.
Journal of neuro-oncology 2017 Louis N, Liu S, He X, Drummond DC, Noble CO, Goldman S, Mueller S, Bankiewicz K, Gupta N, Hashizume R -
Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.
Acta neuropathologica 2017 Chan E, Bollen AW, Sirohi D, Van Ziffle J, Grenert JP, Kline CN, Tihan T, Perry A, Gupta N, Solomon DA -
Surgical techniques for open fetal repair of myelomeningocele.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2017 Gupta N -
Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
Neuro-oncology 2017 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, … -
Metastatic clival chordoma: a case report of multiple extraneural metastases following resection and proton beam radiotherapy in a 5-year old boy.
Journal of neurosurgery. Pediatrics 2017 Rutkowski MJ, Birk HS, Wood MD, Perry A, Nicolaides T, Ames CP, Gupta N -
Pediatric high-grade glioma: biologically and clinically in need of new thinking.
Neuro-oncology 2017 Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, … -
Patient-derived Tumor Models for Diffuse Intrinsic Pontine Gliomas.
Current neuropharmacology 2017 Hashizume R, Gupta N -
Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits.
Journal of neuroinflammation 2016 Feng X, Jopson TD, Paladini MS, Liu S, West BL, Gupta N, Rosi S -
BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Olow A, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss W, Resnick AC, Waanders AJ, Stalpers LJ, Berger MS, Gupta N, James CD, Petritsch CK, Haas-Kogan DA -
Indirect and direct revascularization of ACTA2 cerebral arteriopathy: feasibility of the superficial temporal artery to anterior cerebral artery bypass with posterior auricular artery interposition graft: case report.
Journal of neurosurgery. Pediatrics 2016 Rutledge WC, Choudhri O, Walcott BP, Benet A, Fox CK, Gupta N, Lawton MT -
IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.
Acta neuropathologica 2016 Ferris SP, Goode B, Joseph NM, Kline CN, Samuel D, Gupta N, Bollen A, Perry A, Mueller S, Solomon DA -
Biopsy for diffuse intrinsic pontine glioma: a reappraisal.
Journal of neurosurgery. Pediatrics 2016 Kieran MW, Goumnerova LC, Prados M, Gupta N -
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury.
Journal of neuroinflammation 2016 Morganti JM, Riparip LK, Chou A, Liu S, Gupta N, Rosi S -
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.
The Lancet. Oncology 2016 Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AAN, Giannini C, Li KKW, Ng HK, Yao Y, Kumabe T, … -
Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.
Brain pathology (Zurich, Switzerland) 2015 Solomon DA, Wood MD, Tihan T, Bollen AW, Gupta N, Phillips JJ, Perry A -
Central Adaptation following Brachial Plexus Injury.
World neurosurgery 2015 Simon NG, Franz CK, Gupta N, Alden T, Kliot M -
Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement.
Journal of neurosurgery. Pediatrics 2015 Tulipan N, Wellons JC, Thom EA, Gupta N, Sutton LN, Burrows PK, Farmer D, Walsh W, Johnson MP, Rand L, Tolivaisa S, D'alton ME, Adzick NS, MOMS Investigators -
Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.
Journal of neurosurgery 2015 Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW -
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
Cancer cell 2015 Pajtler KW, Witt H, Sill M, Jones DT, Hovestadt V, Kratochwil F, Wani K, Tatevossian R, Punchihewa C, Johann P, Reimand J, Warnatz HJ, Ryzhova M, Mack S, Ramaswamy V, Capper D, Schweizer L, Sieber L, … -
Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Mack SC, Agnihotri S, Bertrand KC, Wang X, Shih DJ, Witt H, Hill N, Zayne K, Barszczyk M, Ramaswamy V, Remke M, Thompson Y, Ryzhova M, Massimi L, Grajkowska W, Lach B, Gupta N, Weiss WA, Guha A, … -
Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review.
Journal of neurological surgery reports 2015 Barajas RF, Phelps A, Foster HC, Courtier J, Buelow BD, Gupta N, Nicolaides T, Glenn OA, Banerjee A -
CCR2 antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Morganti JM, Jopson TD, Liu S, Riparip LK, Guandique CK, Gupta N, Ferguson AR, Rosi S -
WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma.
Acta neuropathologica communications 2014 Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, Pfaff E, Korshunov A, Jones DT, Northcott… -
Role of fine needle aspiration cytology of spleen.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2014 Gochhait D, Dey P, Rajwanshi A, Nijhawan R, Gupta N, Radhika S, Lal A -
A treatment paradigm for high-grade brain arteriovenous malformations: volume-staged radiosurgical downgrading followed by microsurgical resection.
Journal of neurosurgery 2014 Abla AA, Rutledge WC, Seymour ZA, Guo D, Kim H, Gupta N, Sneed PK, Barani IJ, Larson D, McDermott MW, Lawton MT -
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Nature medicine 2014 Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD -
Pure germinomas of the central nervous system: treatment strategies and outcomes.
Journal of neuro-oncology 2014 Schoenfeld A, Haas-Kogan DA, Molinaro A, Banerjee A, Nicolaides T, Tihan T, Bollen AW, Gupta N, Mueller S -
Management of central nervous system teratoma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2014 Zygourakis CC, Davis JL, Kaur G, Ames CP, Gupta N, Auguste KI, Parsa AT -
Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment.
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA -
Epilepsy surgery failure in children: a quantitative and qualitative analysis.
Journal of neurosurgery. Pediatrics 2014 Englot DJ, Han SJ, Rolston JD, Ivan ME, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI -
Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma.
Journal of neuro-oncology 2014 Sun MZ, Ivan ME, Oh MC, Delance AR, Clark AJ, Safaee M, Oh T, Kaur G, Molinaro A, Gupta N, Parsa AT -
Response.
Journal of neurosurgery. Pediatrics 2014 Cheng JS, Ivan ME, Stapleton CJ, Quinones-Hinojosa A, Gupta N, Auguste KI -
Stereotactic radiosurgery at a low marginal dose for the treatment of pediatric arteriovenous malformations: obliteration, complications, and functional outcomes.
Journal of neurosurgery. Pediatrics 2014 Potts MB, Sheth SA, Louie J, Smyth MD, Sneed PK, McDermott MW, Lawton MT, Young WL, Hetts SW, Fullerton HJ, Gupta N -
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
Nature genetics 2014 Fontebasso AM, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset PO, Bechet D, Faury D, De Jay N, Ramkissoon LA, Corcoran A, Jones DT, Sturm D, Johann P, Tomita T, Goldman S, Nagib … -
Intraoperative changes in transcranial motor evoked potentials and somatosensory evoked potentials predicting outcome in children with intramedullary spinal cord tumors.
Journal of neurosurgery. Pediatrics 2014 Cheng JS, Ivan ME, Stapleton CJ, Quinones-Hinojosa A, Gupta N, Auguste KI -
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration.
PloS one 2014 Morganti JM, Jopson TD, Liu S, Gupta N, Rosi S -
Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: multimodality management, patient selection, and results.
World neurosurgery 2014 Potts MB, Jahangiri A, Jen M, Sneed PK, McDermott MW, Gupta N, Hetts SW, Young WL, Lawton MT, UCSF Brain AVM Study Project -
Influence of patient age on angioarchitecture of brain arteriovenous malformations.
AJNR. American journal of neuroradiology 2014 Hetts SW, Cooke DL, Nelson J, Gupta N, Fullerton H, Amans MR, Narvid JA, Moftakhar P, McSwain H, Dowd CF, Higashida RT, Halbach VV, Lawton MT, Kim H -
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.
Nature 2014 Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, Pugh TJ, Ryzhova M, Wani KM, Shih DJ, Head R, Remke M, … -
Surgical outcomes in spinal cord ependymomas and the importance of extent of resection in children and young adults.
Journal of neurosurgery. Pediatrics 2014 Safaee M, Oh MC, Mummaneni PV, Weinstein PR, Ames CP, Chou D, Berger MS, Parsa AT, Gupta N -
Cytogenetic prognostication within medulloblastoma subgroups.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2014 Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria … -
Targeting Wee1 for the treatment of pediatric high-grade gliomas.
Neuro-oncology 2013 Mueller S, Hashizume R, Yang X, Kolkowitz I, Olow AK, Phillips J, Smirnov I, Tom MW, Prados MD, James CD, Berger MS, Gupta N, Haas-Kogan DA -
Gross total resection improves overall survival in children with choroid plexus carcinoma.
Journal of neuro-oncology 2013 Sun MZ, Ivan ME, Clark AJ, Oh MC, Delance AR, Oh T, Safaee M, Kaur G, Bloch O, Molinaro A, Gupta N, Parsa AT -
Angiographic features help predict outcome after stereotactic radiosurgery for the treatment of pediatric arteriovenous malformations.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Sheth SA, Potts MB, Sneed PK, Young WL, Cooke DL, Gupta N, Hetts SW -
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, Pugh TJ, Pomeroy SL, Cho YJ, … -
Effects of temporal lobectomy on consciousness-impairing and consciousness-sparing seizures in children.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Englot DJ, Rutkowski MJ, Ivan ME, Sun PP, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI -
Histologic grade and extent of resection are associated with survival in pediatric spinal cord ependymomas.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Safaee M, Oh MC, Kim JM, Aranda D, Tarapore PE, Cage TA, Gupta N, Parsa AT -
Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Cage TA, Samagh SP, Mueller S, Nicolaides T, Haas-Kogan D, Prados M, Banerjee A, Auguste KI, Gupta N -
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
Genes & development 2013 Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, Gupta N, Mueller S, James CD, Jenkins R, Sarkaria J, Zhang Z -
A systematic review of treatment outcomes in pediatric patients with intracranial ependymomas.
Journal of neurosurgery. Pediatrics 2013 Cage TA, Clark AJ, Aranda D, Gupta N, Sun PP, Parsa AT, Auguste KI -
Surgical outcomes in choroid plexus papillomas: an institutional experience.
Journal of neuro-oncology 2013 Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT -
Radially branched deployment for more efficient cell transplantation at the scale of the human brain.
Stereotactic and functional neurosurgery 2013 Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA -
Prognosis by tumor location for pediatric spinal cord ependymomas.
Journal of neurosurgery. Pediatrics 2012 Oh MC, Sayegh ET, Safaee M, Sun MZ, Kaur G, Kim JM, Aranda D, Molinaro AM, Gupta N, Parsa AT -
High-precision volume-staged Gamma Knife surgery and equivalent hypofractionation dose schedules for treating large arteriovenous malformations.
Journal of neurosurgery 2012 Fogh S, Ma L, Gupta N, Sahgal A, Nakamura JL, Barani I, Sneed PK, McDermott M, Larson DA -
Expression of miR-124 inhibits growth of medulloblastoma cells.
Neuro-oncology 2012 Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, VandenBerg SR, James CD, Hodgson JG, Gupta N -
A systematic review of the results of surgery and radiotherapy on tumor control for pediatric craniopharyngioma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2012 Clark AJ, Cage TA, Aranda D, Parsa AT, Sun PP, Auguste KI, Gupta N -
Neural stem cell engraftment and myelination in the human brain.
Science translational medicine 2012 Gupta N, Henry RG, Strober J, Kang SM, Lim DA, Bucci M, Caverzasi E, Gaetano L, Mandelli ML, Ryan T, Perry R, Farrell J, Jeremy RJ, Ulman M, Huhn SL, Barkovich AJ, Rowitch DH -
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
Journal of neuro-oncology 2012 Hashizume R, Smirnov I, Liu S, Phillips JJ, Hyer J, McKnight TR, Wendland M, Prados M, Banerjee A, Nicolaides T, Mueller S, James CD, Gupta N -
Treatment-related morbidity and the management of pediatric craniopharyngioma: a systematic review.
Journal of neurosurgery. Pediatrics 2012 Clark AJ, Cage TA, Aranda D, Parsa AT, Auguste KI, Gupta N -
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.
PloS one 2012 Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ -
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Nature 2012 Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, Dubuc A, Yao Y, Ramaswamy … -
Pediatric intracranial nongalenic pial arteriovenous fistulas: clinical features, angioarchitecture, and outcomes.
AJNR. American journal of neuroradiology 2012 Hetts SW, Keenan K, Fullerton HJ, Young WL, English JD, Gupta N, Dowd CF, Higashida RT, Lawton MT, Halbach VV -
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
Neuro-oncology 2012 Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA -
High-grade gliomas in children.
Neurosurgery clinics of North America 2012 Cage TA, Mueller S, Haas-Kogan D, Gupta N -
Open fetal surgery for myelomeningocele.
Journal of neurosurgery. Pediatrics 2012 Gupta N, Farrell JA, Rand L, Cauldwell CB, Farmer D -
The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.
Journal of neuro-oncology 2012 Schoenfeld A, Pekmezci M, Barnes MJ, Tihan T, Gupta N, Lamborn KR, Banerjee A, Mueller S, Chang S, Berger MS, Haas-Kogan D -
Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system.
Clinical & experimental metastasis 2012 Cage TA, Louie JD, Liu SR, Alvarez-Buylla A, Gupta N, Hyer J -
An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing.
Journal of neuro-oncology 2012 Aoki Y, Hashizume R, Ozawa T, Banerjee A, Prados M, James CD, Gupta N -
A technique for achieving submillimeter accuracy of volume-staged stereotactic radiosurgery.
Journal of radiosurgery and SBRT 2012 Ma L, Fogh S, Gupta N, Hwang A, Pinnaduwage D, Nakamura J, Barani I, McDermott M, Sneed PK, Larson DA, Sahgal A -
Pathologic characteristics of pediatric intracranial pilocytic astrocytomas and their impact on outcome in 3 countries: a multi-institutional study.
The American journal of surgical pathology 2012 Tihan T, Ersen A, Qaddoumi I, Sughayer MA, Tolunay S, Al-Hussaini M, Phillips J, Gupta N, Goldhoff P, Baneerjee A -
Corridors of migrating neurons in the human brain and their decline during infancy.
Nature 2011 Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, Rowitch DH, Alvarez-Buylla A -
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.
Cancer cell 2011 Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R, Benner A, Hielscher T, Milde T, Remke M, Jones DT, Northcott PA, Garzia L, Bertrand KC, Wittmann A, Yao Y, Roberts SS, Massimi L, Van Meter T,… -
Pediatric intracranial ependymoma: the roles of surgery, radiation and chemotherapy.
Journal of neuro-oncology 2011 Pejavar S, Polley MY, Rosenberg-Wohl S, Chennupati S, Prados MD, Berger MS, Banerjee A, Gupta N, Haas-Kogan D -
Prevalence of congenital hydrocephalus in California, 1991-2000.
Pediatric neurology 2011 Jeng S, Gupta N, Wrensch M, Zhao S, Wu YW -
Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes.
Neurosurgical focus 2011 Jahangiri A, Molinaro AM, Tarapore PE, Blevins L, Auguste KI, Gupta N, Kunwar S, Aghi MK -
Intraosseous CSF fistula in a patient with Gorham disease resulting in intracranial hypotension.
AJNR. American journal of neuroradiology 2011 Adler F, Gupta N, Hess CP, Dowd CF, Dillon WP -
Microscopic endonasal transsphenoidal pituitary adenomectomy in the pediatric population.
Journal of neurosurgery. Pediatrics 2011 Tarapore PE, Sughrue ME, Blevins L, Auguste KI, Gupta N, Kunwar S -
Self-reported functional outcome after surgical intervention in patients with idiopathic normal pressure hydrocephalus.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2011 Cage TA, Auguste KI, Wrensch M, Wu YW, Gupta N -
A randomized trial of prenatal versus postnatal repair of myelomeningocele.
The New England journal of medicine 2011 Adzick NS, Thom EA, Spong CY, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D'Alton ME, Farmer DL, MOMS Investigators -
Clinicopathological characteristics of adamantinomatous and papillary craniopharyngiomas: University of California, San Francisco experience 1985-2005.
Neurosurgery 2010 Pekmezci M, Louie J, Gupta N, Bloomer MM, Tihan T -
Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome.
AJNR. American journal of neuroradiology 2010 Hess CP, Fullerton HJ, Metry DW, Drolet BA, Siegel DH, Auguste KI, Gupta N, Haggstrom AN, Dowd CF, Frieden IJ, Barkovich AJ -
Diagnosis influences response of cerebral near infrared spectroscopy to intracranial hypertension in children.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010 Zuluaga MT, Esch ME, Cvijanovich NZ, Gupta N, McQuillen PS -
Minimally invasive tethered cord release in adults: a comparison of open and mini-open approaches.
Neurosurgical focus 2010 Potts MB, Wu JC, Gupta N, Mummaneni PV -
Pediatric intracranial aneurysms.
Neurosurgery clinics of North America 2010 Jian BJ, Hetts SW, Lawton MT, Gupta N -
Telomerase inhibitors for the treatment of brain tumors and the potential of intranasal delivery.
Current opinion in molecular therapeutics 2010 Hashizume R, Gupta N -
Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.
Journal of neuro-oncology 2010 Mishra KK, Squire S, Lamborn K, Banerjee A, Gupta N, Wara WM, Prados MD, Berger MS, Haas-Kogan DA -
Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
Neuro-oncology 2010 Hashizume R, Gupta N, Berger MS, Banerjee A, Prados MD, Ayers-Ringler J, James CD, VandenBerg SR -
Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients.
Journal of neurosurgery. Pediatrics 2010 Chang EF, Christie C, Sullivan JE, Garcia PA, Tihan T, Gupta N, Berger MS, Barbaro NM -
Multiple intracranial aneurysms and moyamoya disease associated with microcephalic osteodysplastic primordial dwarfism type II: surgical considerations.
Journal of neurosurgery. Pediatrics 2009 Waldron JS, Hetts SW, Armstrong-Wells J, Dowd CF, Fullerton HJ, Gupta N, Lawton MT -
A human brainstem glioma xenograft model enabled for bioluminescence imaging.
Journal of neuro-oncology 2009 Hashizume R, Ozawa T, Dinca EB, Banerjee A, Prados MD, James CD, Gupta N -
Chiari type I malformation in a pediatric population.
Pediatric neurology 2009 Aitken LA, Lindan CE, Sidney S, Gupta N, Barkovich AJ, Sorel M, Wu YW -
Imaging of ependymomas: MRI and CT.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2009 Yuh EL, Barkovich AJ, Gupta N -
Intracranial aneurysms in childhood: 27-year single-institution experience.
AJNR. American journal of neuroradiology 2009 Hetts SW, Narvid J, Sanai N, Lawton MT, Gupta N, Fullerton HJ, Dowd CF, Higashida RT, Halbach VV -
Transcerebellar stereotactic biopsy for lesions of the brainstem and peduncles under local anesthesia.
Neurosurgery 2008 Sanai N, Wachhorst SP, Gupta NM, McDermott MW -
Radiation is an important component of multimodality therapy for pediatric non-pineal supratentorial primitive neuroectodermal tumors.
International journal of radiation oncology, biology, physics 2008 McBride SM, Daganzo SM, Banerjee A, Gupta N, Lamborn KR, Prados MD, Berger MS, Wara WM, Haas-Kogan DA -
Cervical spine trauma in the pediatric patient.
Neurosurgery clinics of North America 2007 Klimo P, Ware ML, Gupta N, Brockmeyer D -
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
Journal of neurosurgery 2007 Dinca EB, Sarkaria JN, Schroeder MA, Carlson BL, Voicu R, Gupta N, Berger MS, James CD -
Ventriculoperitoneal shunt complications in California: 1990 to 2000.
Neurosurgery 2007 Wu Y, Green NL, Wrensch MR, Zhao S, Gupta N -
CC chemokine receptor-2A is frequently overexpressed in glioblastoma.
Journal of neuro-oncology 2007 Liang Y, Bollen AW, Gupta N -
Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment.
Journal of neuro-oncology 2007 Liang Y, Diehn M, Bollen AW, Israel MA, Gupta N -
Diagnosis of Chiari III malformation by second trimester fetal MRI with postnatal MRI and CT correlation.
Pediatric radiology 2007 Smith AB, Gupta N, Otto C, Glenn OA -
Complications of lumboperitoneal shunts.
Neurosurgery 2007 Wang VY, Barbaro NM, Lawton MT, Pitts L, Kunwar S, Parsa AT, Gupta N, McDermott MW -
Long-term outcomes in patients with treated childhood hydrocephalus.
Journal of neurosurgery 2007 Gupta N, Park J, Solomon C, Kranz DA, Wrensch M, Wu YW -
The effects of detethering on the urodynamics profile in children with a tethered cord.
Journal of neurosurgery 2006 Hsieh MH, Perry V, Gupta N, Pearson C, Nguyen HT -
Intracranial dermoid cyst mimicking hemorrhage. Case report and review of the literature.
Journal of neurosurgery 2006 Sanchez-Mejia RO, Limbo M, Tihan T, Galvez MG, Woodward MV, Gupta N -
Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations.
Journal of neurosurgery 2006 Sanchez-Mejia RO, Chennupati SK, Gupta N, Fullerton H, Young WL, Lawton MT -
Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma.
BMC cancer 2006 Liang Y, Bollen AW, Aldape KD, Gupta N -
Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial mass lesions.
Journal of neuro-oncology 2006 Smith JS, Lin H, Mayo MC, Bannerjee A, Gupta N, Perry V, Cha S -
The role of up-front radiation therapy for incompletely resected pediatric WHO grade II low-grade gliomas.
Neuro-oncology 2006 Mishra KK, Puri DR, Missett BT, Lamborn KR, Prados MD, Berger MS, Banerjee A, Gupta N, Wara WM, Haas-Kogan DA -
A modification of the Mayfield horseshoe headrest allowing pin fixation and cranial immobilization in infants and young children.
Neurosurgery 2006 Gupta N -
Pediatric intracranial aneurysms: durability of treatment following microsurgical and endovascular management.
Journal of neurosurgery 2006 Sanai N, Quinones-Hinojosa A, Gupta NM, Perry V, Sun PP, Wilson CB, Lawton MT -
Pediatric intramedullary spinal cord tumors.
Neurosurgery clinics of North America 2006 Auguste KI, Gupta N -
Airbag deployment and improperly restrained children: a lethal combination.
The Journal of trauma 2005 Quiñones-Hinojosa A, Jun P, Manley GT, Knudson MM, Gupta N -
Time trends and demographics of deaths from congenital hydrocephalus in children in the United States: National Center for Health Statistics data, 1979 to 1998.
Journal of neurosurgery 2005 Chi JH, Fullerton HJ, Gupta N -
Id4 and FABP7 are preferentially expressed in cells with astrocytic features in oligodendrogliomas and oligoastrocytomas.
BMC clinical pathology 2005 Liang Y, Bollen AW, Nicholas MK, Gupta N -
Changes in transcranial motor evoked potentials during intramedullary spinal cord tumor resection correlate with postoperative motor function.
Neurosurgery 2005 Quiñones-Hinojosa A, Lyon R, Zada G, Lamborn KR, Gupta N, Parsa AT, McDermott MW, Weinstein PR -
Neurocutaneous melanosis presenting with hydrocephalus. Case report and review of the literature.
Journal of neurosurgery 2005 Acosta FL, Binder DK, Barkovich AJ, Frieden IJ, Gupta N -
Radiation-induced atypical meningioma with rapid growth in a 13-year-old girl. Case report.
Journal of neurosurgery 2004 Ware ML, Cha S, Gupta N, Perry VL -
Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis.
International journal of cancer 2004 Khodarev NN, Labay E, Darga T, Yu J, Mauceri H, Gupta N, Kataoka Y, Weichselbaum RR -
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration.
Nature 2004 Sanai N, Tramontin AD, Quiñones-Hinojosa A, Barbaro NM, Gupta N, Kunwar S, Lawton MT, McDermott MW, Parsa AT, Manuel-García Verdugo J, Berger MS, Alvarez-Buylla A -
Neurodevelopmental outcome after endovascular treatment of vein of Galen malformations.
Neurology 2003 Fullerton HJ, Aminoff AR, Ferriero DM, Gupta N, Dowd CF -
Choroid plexus tumors in children.
Neurosurgery clinics of North America 2003 Gupta N -
In utero repair of myelomeningocele: experimental pathophysiology, initial clinical experience, and outcomes.
Archives of surgery (Chicago, Ill. : 1960) 2003 Farmer DL, von Koch CS, Peacock WJ, Danielpour M, Gupta N, Lee H, Harrison MR -
In utero surgery for hydrocephalus.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2003 von Koch CS, Gupta N, Sutton LN, Sun PP -
Brain mapping for hemispheric tumors in children.
Pediatric neurosurgery 2003 Gupta N, Berger MS -
Cystic schwannoma of the anterior tentorial hiatus. Case report and review of the literature.
Pediatric neurosurgery 2003 Du R, Dhoot J, McDermott MW, Gupta N -
Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp.
Emerging infectious diseases 2003 Sohn AH, Probert WS, Glaser CA, Gupta N, Bollen AW, Wong JD, Grace EM, McDonald WC -
Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
Journal of cell science 2003 Khodarev NN, Yu J, Labay E, Darga T, Brown CK, Mauceri HJ, Yassari R, Gupta N, Weichselbaum RR -
Spinal cord mapping as an adjunct for resection of intramedullary tumors: surgical technique with case illustrations.
Neurosurgery 2002 Quinones-Hinojosa A, Gulati M, Lyon R, Gupta N, Yingling C -
Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Proceedings of the National Academy of Sciences of the United States of America 2001 Khodarev NN, Park JO, Yu J, Gupta N, Nodzenski E, Roizman B, Weichselbaum RR -
Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
Molecular pathology : MP 2001 Gupta N, Wang H, McLeod TL, Naus CC, Kyurkchiev S, Advani S, Yu J, Perbal B, Weichselbaum RR -
Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation.
Seminars in radiation oncology 2001 Chmura SJ, Gupta N, Advani SJ, Kufe DW, Weichselbaum RR -
Angiostatin effects on endothelial cells mediated by ceramide and RhoA.
EMBO reports 2001 Gupta N, Nodzenski E, Khodarev NN, Yu J, Khorasani L, Beckett MA, Kufe DW, Weichselbaum RR -
Quantitative analysis of DNA array autoradiographs.
Nucleic acids research 2000 Pelizzari CA, Khodarev NN, Gupta N, Calvin DP, Weichselbaum RR -
Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.
Proceedings of the National Academy of Sciences of the United States of America 1999 Khodarev NN, Advani SJ, Gupta N, Roizman B, Weichselbaum RR -
Induction and characterization of human glioma clones with different radiosensitivities.
Neoplasia (New York, N.Y.) 1999 Wang J, Hu L, Gupta N, Shamseldin T, Ozawa T, Klem J, Cardell M, Deen DF -
Response of postmitotic neurons to X-irradiation: implications for the role of DNA damage in neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998 Gobbel GT, Bellinzona M, Vogt AR, Gupta N, Fike JR, Chan PH -
Cytotoxicity and cell-cycle effects of paclitaxel when used as a single agent and in combination with ionizing radiation.
International journal of radiation oncology, biology, physics 1997 Gupta N, Hu LJ, Deen DF -
A statistical approach for analyzing clonogenic survival data.
Radiation research 1996 Gupta N, Lamborn K, Deen DF -
Cytogenetic damage and the radiation-induced G1-phase checkpoint.
Radiation research 1996 Gupta N, Vij R, Haas-Kogan DA, Israel MA, Deen DF, Morgan WF -
Comments on the use of paclitaxel as a radiation sensitizer.
International journal of radiation oncology, biology, physics 1995 Gupta N, Deen DF