Najwa El-Nachef, MD
Professor
Medicine
School of Medicine

Education & Training

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• Gastroenterology Fellowship UCSF 2011
• Internal Medicine Residency University of Michigan 2007
• M.D. School of Medicine Wayne State University 2004

Interests

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• Balloon Assisted Enteroscopy
• Intestinal Microbiome
• Inflammatory Bowel Disease
• Celiac Disease
• Fecal Microbiota Transplant

Publications (25)

Top publication keywords:
Clostridium InfectionsEndoscopy, GastrointestinalSigmoid NeoplasmsFecal Microbiota TransplantationGastrointestinal HemorrhageCathetersColitis, UlcerativeDysbiosisColonoscopyCrohn DiseaseMeckel DiverticulumDuodenal DiseasesGastrointestinal MicrobiomeInflammatory Bowel DiseasesPouchitis

• Safety and Tolerability of CP101, a Full-Spectrum, Oral Microbiome Therapeutic for the Prevention of Recurrent Clostridioides difficile Infection: A Phase 2 Randomized Controlled Trial.
  Gastroenterology 2024 Allegretti JR, Kelly CR, Louie T, Fischer M, Hota S, Misra B, Van Hise NW, Yen E, Bullock JS, Silverman M, Davis I, McGill SK, Pardi DS, Orenstein R, Grinspan A, El-Nachef N, Feuerstadt P, Borody TJ, …
• Sustained mucosal colonization and fecal metabolic dysfunction by Bacteroides associates with fecal microbial transplant failure in ulcerative colitis patients.
  Scientific reports 2024 Zhang B, Magnaye KM, Stryker E, Moltzau-Anderson J, Porsche CE, Hertz S, McCauley KE, Smith BJ, Zydek M, Pollard KS, Ma A, El-Nachef N, Lynch SV
• Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis.
  Nature communications 2024 Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck …
• Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis.
  bioRxiv : the preprint server for biology 2024 Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck …
• Multicentre Real-world Experience of Upadacitinib in the Treatment of Crohn's Disease.
  Journal of Crohn's & colitis 2023 Chugh R, Braga-Neto MB, Fredrick TW, Ramos GP, Terdiman J, El-Nachef N, Loftus EV, Mahadevan U, Kane SV

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• Painless Rectal Bleeding in a Patient With Prostate Cancer.
  Gastroenterology 2022 Medina SP, Wong AC, El-Nachef N
• Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis.
  Scientific reports 2022 Smith BJ, Piceno Y, Zydek M, Zhang B, Syriani LA, Terdiman JP, Kassam Z, Ma A, Lynch SV, Pollard KS, El-Nachef N
• Gender and Other Factors Associated with Endoscopy Volume Among U.S. Gastroenterology Fellows.
  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021 Lenhart A, Chen F, Condon A, Kardashian A, El-Nachef N, UCLA GI DIVISION BIOSTATISTICS, Chang L
• New-Onset of Inflammatory Bowel Disease in a Patient Treated With Teprotumumab for Thyroid Associated Ophthalmopathy.
  Ophthalmic plastic and reconstructive surgery 2021 Ashraf DC, Jankovic I, El-Nachef N, Winn BJ, Kim GE, Kersten RC
• An Unusual Mechanical Cause of Upper Gastrointestinal Hemorrhage.
  Gastroenterology 2020 Ha NB, Wang CW, El-Nachef N
• Fecal microbial transplant for inflammatory bowel disease.
  Current opinion in clinical nutrition and metabolic care 2020 Claytor JD, El-Nachef N
• Fecal Microbiota Transplantation Is Safe and Effective in Patients With Clostridioides difficile Infection and Cirrhosis.
  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020 Cheng YW, Alhaffar D, Saha S, Khanna S, Bohm M, Phelps E, Ghabril M, Orman E, Sashidhar S, Rogers N, Xu H, Khoruts A, Vaughn B, Kao D, Wong K, Cammarota G, Ianiro G, Dhere T, Kraft CS, Mehta N, …
• Effect of individualized feedback on learning curves in EGD and colonoscopy: a cluster randomized controlled trial.
  Gastrointestinal endoscopy 2019 Han S, Obuch JC, Keswani RN, Hall M, Patel SG, Menard-Katcher P, Simon V, Ezekwe E, Aagaard E, Ahmad A, Alghamdi S, Austin K, Brimhall B, Broy C, Carlin L, Cooley M, Di Palma JA, Duloy AM, Early DS, …
• Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study.
  Digestive diseases and sciences 2019 Selvig D, Piceno Y, Terdiman J, Zydek M, Umetsu SE, Balitzer D, Fadrosh D, Lynch K, Lamere B, Leith T, Kassam Z, Beck K, Lewin S, Ma A, Somsouk M, Lynch SV, El-Nachef N
• An unusual cause of massive GI hemorrhage in an adult.
  Gastrointestinal endoscopy 2019 Feuille C, Carter J, El-Nachef N
• Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile.
  United European gastroenterology journal 2019 Gutin L, Piceno Y, Fadrosh D, Lynch K, Zydek M, Kassam Z, LaMere B, Terdiman J, Ma A, Somsouk M, Lynch S, El-Nachef N
• Capsule-Delivered Fecal Microbiota Transplant Is Safe and Well Tolerated in Patients with Ulcerative Colitis.
  Digestive diseases and sciences 2019 Adler E, Tabaa A, Kassam Z, Zydek M, Terdiman J, El-Nachef N
• Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: A multicenter experience.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018 Cheng YW, Phelps E, Ganapini V, Khan N, Ouyang F, Xu H, Khanna S, Tariq R, Friedman-Moraco RJ, Woodworth MH, Dhere T, Kraft CS, Kao D, Smith J, Le L, El-Nachef N, Kaur N, Kowsika S, Ehrlich A, Smith M…
• Effect of I-scan Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy.
  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018 Kidambi TD, Terdiman JP, El-Nachef N, Singh A, Kattah MG, Lee JK
• The Current Landscape and Lessons from Fecal Microbiota Transplantation for Inflammatory Bowel Disease: Past, Present, and Future.
  Inflammatory bowel diseases 2017 Allegretti J, Eysenbach LM, El-Nachef N, Fischer M, Kelly C, Kassam Z
• Fecal microbial therapy: promises and pitfalls.
  Journal of pediatric gastroenterology and nutrition 2014 Merenstein D, El-Nachef N, Lynch SV
• Adherence to colorectal cancer screening: a randomized clinical trial of competing strategies.
  Archives of internal medicine 2012 Inadomi JM, Vijan S, Janz NK, Fagerlin A, Thomas JP, Lin YV, Muñoz R, Lau C, Somsouk M, El-Nachef N, Hayward RA
• Anti-tumor necrosis factor therapy for inflammatory bowel disease in the setting of immunosuppression for solid organ transplantation.
  The American journal of gastroenterology 2010 El-Nachef N, Terdiman J, Mahadevan U
• Changing perceptions and practices regarding aspirin, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs among US primary care providers.
  Alimentary pharmacology & therapeutics 2008 Elnachef N, Scheiman JM, Fendrick AM, Howden CW, Chey WD
• Successful treatment of common variable immunodeficiency disorder-associated diarrhea with budesonide: a case report.
  The American journal of gastroenterology 2007 Elnachef N, McMorris M, Chey WD