Murad Mamedov, PhD
Scientist
Business Service Ctr
Chancellor/EVC/FAS

Education & Training

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• Ph.D. Immunology Stanford University 06/2017
• B.S. Biology, Philosophy Georgetown University 05/2010

Interests

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• Malaria
• T cell receptor
• gamma-delta T cells
• Cancer

Websites

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• @@MuradRMamedov on Twitter (twitter.com)

Grants and Projects

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• , Michelson Prize for Human Immunology and Vaccine Development, 2019-2020
• , Cancer Research Institute (CRI) Irvington Postdoctoral Fellowship, 2019

Publications (7)

Top publication keywords:
DNA, Single-StrandedT-Lymphocyte SubsetsReceptors, Antigen, T-Cell, gamma-deltaAMP-Activated Protein KinasesGenes, ImmunoglobulinT-LymphocytesMalariaV(D)J RecombinationCRISPR-Cas SystemsHepatitis delta AntigensGene EditingGenes, T-Cell ReceptorMacrophage Colony-Stimulating FactorNeoplasmsParasitemia

• CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
  Nature 2023 Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A
• Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report.
  Annals of the New York Academy of Sciences 2023 Cable J, Rathmell JC, Pearce EL, Ho PC, Haigis MC, Mamedov MR, Wu MJ, Kaech SM, Lynch L, Febbraio MA, Bapat SP, Hong HS, Zou W, Belkaid Y, Sullivan ZA, Keller A, Wculek SK, Green DR, Postic C, Amit I,…
• High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.
  Nature biotechnology 2022 Shy BR, Vykunta VS, Ha A, Talbot A, Roth TL, Nguyen DN, Pfeifer WG, Chen YY, Blaeschke F, Shifrut E, Vedova S, Mamedov MR, Chung JJ, Li H, Yu R, Wu D, Wolf J, Martin TG, Castro CE, Ye L, Esensten JH, …
• Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.
  Nature biotechnology 2019 Nguyen DN, Roth TL, Li PJ, Chen PA, Apathy R, Mamedov MR, Vo LT, Tobin VR, Goodman D, Shifrut E, Bluestone JA, Puck JM, Szoka FC, Marson A
• A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
  Immunity 2018 Mamedov MR, Scholzen A, Nair RV, Cumnock K, Kenkel JA, Oliveira JHM, Trujillo DL, Saligrama N, Zhang Y, Rubelt F, Schneider DS, Chien YH, Sauerwein RW, Davis MM
• Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells.
  Nature communications 2016 Rubelt F, Bolen CR, McGuire HM, Vander Heiden JA, Gadala-Maria D, Levin M, Euskirchen GM, Mamedov MR, Swan GE, Dekker CL, Cowell LG, Kleinstein SH, Davis MM
• Arginine-rich motifs are not required for hepatitis delta virus RNA binding activity of the hepatitis delta antigen.
  Journal of virology 2013 Daigh LH, Griffin BL, Soroush A, Mamedov MR, Casey JL