Milos Simic, PhD
Assistant Researcher
Cellular Molecular Pharmacology
School of Medicine

Publications (8)

Top publication keywords:
Peptide LibraryCellular ReprogrammingEncephalomyelitis, Autoimmune, ExperimentalInduced Pluripotent Stem CellsHeat-Shock ResponseUnfolded Protein ResponseNeural Stem CellsCytosolFibroblastsLysosomesT-Lymphocytes, CytotoxicEndoplasmic Reticulum StressReceptors, Opioid, deltaEndoplasmic ReticulumImmunotherapy, Adoptive

• CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity.
  Neurology(R) neuroimmunology & neuroinflammation 2023 Gupta S, Simic M, Sagan SA, Shepherd C, Duecker J, Sobel RA, Dandekar R, Wu GF, Wu W, Pak JE, Hauser SL, Lim W, Wilson MR, Zamvil SS
• Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning.
  Science (New York, N.Y.) 2022 Daniels KG, Wang S, Simic MS, Bhargava HK, Capponi S, Tonai Y, Yu W, Bianco S, Lim WA
• Endocytic trafficking determines cellular tolerance of presynaptic opioid signaling.
  eLife 2022 Jullié D, Benitez C, Knight TA, Simic MS, von Zastrow M
• SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma.
  Science translational medicine 2021 Choe JH, Watchmaker PB, Simic MS, Gilbert RD, Li AW, Krasnow NA, Downey KM, Yu W, Carrera DA, Celli A, Cho J, Briones JD, Duecker JM, Goretsky YE, Dannenfelser R, Cardarelli L, Troyanskaya O, Sidhu SS…
• Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming.
  Science advances 2019 Simic MS, Moehle EA, Schinzel RT, Lorbeer FK, Halloran JJ, Heydari K, Sanchez M, Jullié D, Hockemeyer D, Dillin A
• The Lysosome, Elixir of Neural Stem Cell Youth.
  Cell stem cell 2018 Simic MS, Dillin A
• Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.
  Cell 2016 Kim HE, Grant AR, Simic MS, Kohnz RA, Nomura DK, Durieux J, Riera CE, Sanchez M, Kapernick E, Wolff S, Dillin A
• Proteostasis and aging of stem cells.
  Trends in cell biology 2013 Vilchez D, Simic MS, Dillin A