Michela Faggioni, MD
Assistant Professor
Medicine
School of Medicine

Dr. Michela Faggioni is an interventional cardiologist, a specialist in minimally invasive procedures to address heart conditions. She treats acute and chronic coronary syndromes (conditions in which blood flow to the heart is suddenly reduced) and heart valve diseases. In addition, she performs left atrial appendage occlusions (closing a small pouch in the heart’s upper left chamber to prevent clots), patent foramen ovale occlusions (closing a hole between the heart's upper chambers to prevent clots) and renal denervations (destroying nerves in arteries supplying the kidneys as a treatment for high blood pressure).

Research Interests

Dr Faggioni’s research focuses on ways to improve clinical outcomes for patients having interventional cardiology procedures.

• The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT.
  JCI insight 2022 Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM, Pfeifer K, Knollmann BC
• Seeking patient-centered trial outcomes: The case for days alive out of hospital.
  American heart journal 2021 Faggioni M, Fanaroff AC
• Epicardial Ablation Complications.
  Cardiac electrophysiology clinics 2020 Tarantino N, Della Rocca DG, Faggioni M, Zhang XD, Mohanty S, Anannab A, Canpolat U, Ayhan H, Bassiouny M, Sahore A, Aytemir K, Sarcon A, Forleo GB, Lavalle C, Horton RP, Trivedi C, Al-Ahmad A, Romero…
• Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure.
  Cardiac failure review 2020 Faggioni M, Della Rocca DG, Mohanty S, Trivedi C, Canpolat U, Gianni C, Al-Ahmad A, Horton R, Gallinghouse GJ, Burkhardt JD, Natale A
• State of Fluoroless Procedures in Cardiac Electrophysiology Practice.
  The Journal of innovations in cardiac rhythm management 2020 Canpolat U, Faggioni M, Della Rocca DG, Chen Q, Ayhan H, Vu AA, Mohanty S, Trivedi C, Gianni C, Bassiouny M, Al-Ahmad A, Burkhardt JD, Sanchez JE, Gallinghouse GJ, Natale A, Horton RP
• Impact of insulin treated and non-insulin-treated diabetes compared to patients without diabetes on 1-year outcomes following contemporary PCI.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2020 Chandrasekhar J, Dangas G, Baber U, Sartori S, Qadeer A, Aquino M, Vogel B, Faggioni M, Vijay P, Claessen BE, Goel R, Moreno P, Krishnan P, Kovacic JC, Kini A, Mehran R, Sharma S
• Comparison of Age (<75 Years Vs ≥75 Years) and Platelet Reactivity to the Risk of Thrombotic and Bleeding Events After Successful Percutaneous Coronary Intervention With Drug-Eluting Stents (from the ADAPT-DES Study).
  The American journal of cardiology 2019 Faggioni M, Redfors B, Crowley A, Claessen BE, Farhan S, Mastoris I, Witzenbichler B, Maehara A, Weisz G, Généreux P, Ben-Yehuda O, Mehran R, Kirtane AJ, Stone GW
• Edwards SAPIEN Versus Medtronic Aortic Bioprosthesis in Women Undergoing Transcatheter Aortic Valve Implantation (from the Win-TAVI Registry).
  The American journal of cardiology 2019 Giannini C, Petronio AS, Mehilli J, Sartori S, Chandrasekhar J, Faggioni M, Lefèvre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem NM, Meliga E, Dumonteil N, Fraccaro C,…
• Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload.
  Frontiers in physiology 2019 Hwang HS, Baldo MP, Rodriguez JP, Faggioni M, Knollmann BC
• Geographical Variations in Patterns of DAPT Cessation and Two-Year PCI Outcomes: Insights from the PARIS Registry.
  Thrombosis and haemostasis 2019 Vogel B, Chandrasekhar J, Baber U, Mastoris I, Sartori S, Aquino M, Krucoff MW, Moliterno DJ, Henry TD, Weisz G, Gibson CM, Iakovou I, Kini AS, Farhan S, Sorrentino S, Faggioni M, Colombo A, Steg PG, …
• Dual-Antiplatelet Therapy Cessation and Cardiovascular Risk in Relation to Age: Analysis From the PARIS Registry.
  JACC. Cardiovascular interventions 2019 Joyce LC, Baber U, Claessen BE, Sartori S, Chandrasekhar J, Cohen DJ, Henry TD, Ariti C, Dangas G, Faggioni M, Aoi S, Gibson CM, Aquino M, Krucoff MW, Vogel B, Moliterno DJ, Sorrentino S, Colombo A, …
• Influence of Baseline Anemia on Dual Antiplatelet Therapy Cessation and Risk of Adverse Events After Percutaneous Coronary Intervention.
  Circulation. Cardiovascular interventions 2019 Faggioni M, Baber U, Sartori S, Chandrasekhar J, Cohen DJ, Henry TD, Claessen BE, Dangas GD, Gibson CM, Krucoff MW, Vogel B, Moliterno DJ, Sorrentino S, Colombo A, Chieffo A, Kini A, Farhan S, Ariti C…
• Use of prasugrel and clinical outcomes in African-American patients treated with percutaneous coronary intervention for acute coronary syndromes.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2019 Faggioni M, Baber U, Chandrasekhar J, Sartori S, Weintraub W, Rao SV, Vogel B, Claessen B, Kini A, Effron M, Ge Z, Keller S, Strauss C, Snyder C, Toma C, Weiss S, Aquino M, Baker B, Defranco A, …
• Use of prasugrel vs clopidogrel and outcomes in patients with and without diabetes mellitus presenting with acute coronary syndrome undergoing percutaneous coronary intervention.
  International journal of cardiology 2018 Faggioni M, Baber U, Chandrasekhar J, Sartori S, Claessen BE, Rao SV, Vogel B, Effron MB, Poddar K, Farhan S, Kini A, Weintraub W, Toma C, Sorrentino S, Weiss S, Snyder C, Muhlestein JB, Kapadia S, …
• The prevalence, predictors and outcomes of guideline-directed medical therapy in patients with acute myocardial infarction undergoing PCI, an analysis from the PROMETHEUS registry.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2018 Ge Z, Baber U, Claessen BE, Farhan S, Chandrasekhar J, Li SX, Sartori S, Kini AS, Rao SV, Weiss S, Henry TD, Vogel B, Sorrentino S, Faggioni M, Kapadia S, Muhlestein B, Strauss C, Toma C, DeFranco A, …
• Temporal trends, determinants, and impact of high-intensity statin prescriptions after percutaneous coronary intervention: Results from a large single-center prospective registry.
  American heart journal 2018 Guedeney P, Baber U, Claessen B, Aquino M, Camaj A, Sorrentino S, Vogel B, Farhan S, Faggioni M, Chandrasekhar J, Kalkman DN, Kovacic JC, Sweeny J, Barman N, Moreno P, Vijay P, Shah S, Dangas G, Kini …
• Effect of a Contrast Modulation System on Contrast Media Use and the Rate of Acute Kidney Injury After Coronary Angiography.
  JACC. Cardiovascular interventions 2018 Mehran R, Faggioni M, Chandrasekhar J, Angiolillo DJ, Bertolet B, Jobe RL, Al-Joundi B, Brar S, Dangas G, Batchelor W, Prasad A, Gurm HS, Tumlin J, Stone GW
• Dual Antiplatelet Therapy Cessation and Adverse Events After Drug-Eluting Stent Implantation in Patients at High Risk for Atherothrombosis (from the PARIS Registry).
  The American journal of cardiology 2018 Sorrentino S, Giustino G, Baber U, Sartori S, Cohen DJ, Henry TD, Farhan S, Sharma M, Ariti C, Dangas G, Gibson M, Faggioni M, Krucoff MW, Aquino M, Chandrasekhar J, Moliterno DJ, Colombo A, Vogel B, …
• Safety and efficacy of nonvitamin K antagonist oral anticoagulants during catheter ablation of atrial fibrillation: A systematic review and meta-analysis.
  Cardiovascular therapeutics 2018 Ge Z, Faggioni M, Baber U, Sartori S, Sorrentino S, Farhan S, Chandrasekhar J, Vogel B, Qadeer A, Halperin J, Reddy V, Dukkipati S, Dangas G, Mehran R
• Effects of Body Mass Index on Clinical Outcomes in Female Patients Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents: Results From a Patient-Level Pooled Analysis of Randomized Controlled Trials.
  JACC. Cardiovascular interventions 2017 Faggioni M, Baber U, Afshar AE, Giustino G, Sartori S, Sorrentino S, Steg PG, Stefanini GG, Windecker S, Leon MB, Stone GW, Wijns W, Serruys PW, Valgimigli M, Camenzind E, Weisz G, Smits PC, Kandzari …
• Associations Between Chronic Kidney Disease and Outcomes With Use of Prasugrel Versus Clopidogrel in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A Report From the PROMETHEUS Study.
  JACC. Cardiovascular interventions 2017 Baber U, Chandrasekhar J, Sartori S, Aquino M, Kini AS, Kapadia S, Weintraub W, Muhlestein JB, Vogel B, Faggioni M, Farhan S, Weiss S, Strauss C, Toma C, DeFranco A, Baker BA, Keller S, Effron MB, …
• Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration.
  JAMA cardiology 2017 Giustino G, Harari R, Baber U, Sartori S, Stone GW, Leon MB, Windecker S, Serruys PW, Kastrati A, Von Birgelen C, Kimura T, Stefanini GG, Dangas GD, Wijns W, Steg PG, Morice MC, Camenzind E, Weisz G, …
• Patterns and associations between DAPT cessation and 2-year clinical outcomes in left main/proximal LAD versus other PCI: Results from the Patterns of Non-Adherence to Dual Antiplatelet Therapy in Stented Patients (PARIS) registry.
  International journal of cardiology 2017 Chandrasekhar J, Baber U, Sartori S, Aquino M, Tomey M, Kruckoff M, Moliterno D, Henry TD, Weisz G, Gibson CM, Iakovou I, Kini A, Faggioni M, Vogel B, Farhan S, Colombo A, Steg PG, Witzenbichler B, …
• Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents.
  Journal of the American College of Cardiology 2017 Sorrentino S, Giustino G, Mehran R, Kini AS, Sharma SK, Faggioni M, Farhan S, Vogel B, Indolfi C, Dangas GD
• Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry.
  JACC. Cardiovascular interventions 2017 Faggioni M, Baber U, Sartori S, Giustino G, Cohen DJ, Henry TD, Farhan S, Ariti C, Dangas G, Gibson M, Giacoppo D, Krucoff MW, Aquino M, Chandrasekhar J, Moliterno DJ, Colombo A, Vogel B, Chieffo A, …
• Cerebral Embolic Protection During TAVR: A Clinical Event Meta-Analysis.
  Journal of the American College of Cardiology 2017 Giustino G, Sorrentino S, Mehran R, Faggioni M, Dangas G
• Impact of Diabetes Mellitus on Ischemic Events in Men and Women After Percutaneous Coronary Intervention.
  The American journal of cardiology 2017 Farhan S, Baber U, Vogel B, Aquino M, Chandrasekhar J, Faggioni M, Giustino G, Kautzky-Willer A, Sweeny J, Shah S, Vijay P, Barman N, Moreno P, Kovacic J, Dangas G, Kini A, Mehran R, Sharma S
• CABG Beats Vintage PCI: Does Contemporary PCI Stand a Chance to EXCEL?
  JACC. Cardiovascular interventions 2016 Mehran R, Faggioni M
• Dual-Imaging Stress Echocardiography for Prognostic Assessment of High-Risk Asymptomatic Patients with Diabetes Mellitus.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2016 Cortigiani L, Gherardi S, Faggioni M, Bovenzi F, Picano E, Petersen C, Molinaro S, Sicari R
• Neurological Outcomes With Embolic Protection Devices in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  JACC. Cardiovascular interventions 2016 Giustino G, Mehran R, Veltkamp R, Faggioni M, Baber U, Dangas GD
• Preventing Contrast-induced Renal Failure: A Guide.
  Interventional cardiology (London, England) 2016 Faggioni M, Mehran R
• Impact of proton pump inhibitors and dual antiplatelet therapy cessation on outcomes following percutaneous coronary intervention: Results From the PARIS Registry.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016 Chandrasekhar J, Bansilal S, Baber U, Sartori S, Aquino M, Farhan S, Vogel B, Faggioni M, Giustino G, Ariti C, Colombo A, Chieffo A, Kini A, Saporito R, Michael Gibson C, Witzenbichler B, Cohen D, …
• Acute and 30-Day Outcomes in Women After TAVR: Results From the WIN-TAVI (Women's INternational Transcatheter Aortic Valve Implantation) Real-World Registry.
  JACC. Cardiovascular interventions 2016 Chieffo A, Petronio AS, Mehilli J, Chandrasekhar J, Sartori S, Lefèvre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem NM, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D…
• Culprit-lesion only versus complete multivessel percutaneous intervention in ST-elevation myocardial infarction: A systematic review and meta-analysis of randomized trials.
  International journal of cardiology 2016 Villablanca PA, Briceno DF, Massera D, Hlinomaz O, Lombardo M, Bortnick AE, Menegus MA, Pyo RT, Garcia MJ, Mookadam F, Ramakrishna H, Wiley J, Faggioni M, Dangas GD
• Sex-related differences in outcomes among men and women under 55 years of age with acute coronary syndrome undergoing percutaneous coronary intervention: Results from the PROMETHEUS study.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016 Chandrasekhar J, Baber U, Sartori S, Faggioni M, Aquino M, Kini A, Weintraub W, Rao S, Kapadia S, Weiss S, Strauss C, Toma C, Muhlestein B, DeFranco A, Effron M, Keller S, Baker B, Pocock S, Henry T, …
• Target lesion failure with BRS? good old DES to the rescue.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2016 Faggioni M, Mehran R
• Advances in dual therapy stenting.
  Minerva cardioangiologica 2016 Giustino G, Faggioni M, Mehran R
• Comparison of Percutaneous Mitral Valve Repair Versus Conservative Treatment in Severe Functional Mitral Regurgitation.
  The American journal of cardiology 2015 Giannini C, Fiorelli F, De Carlo M, Guarracino F, Faggioni M, Giordano P, Spontoni P, Pieroni A, Petronio AS
• Arrhythmia Protection in Hypokalemia: A Novel Role of Ca2+-Activated K+ Currents in the Ventricle.
  Circulation 2015 Faggioni M, Knollmann BC
• Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target?
  Trends in cardiovascular medicine 2014 Faggioni M, van der Werf C, Knollmann BC
• Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.
  Circulation research 2014 Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL, Cornea RL, Bers DM, Knollmann BC
• Suppression of spontaneous ca elevations prevents atrial fibrillation in calsequestrin 2-null hearts.
  Circulation. Arrhythmia and electrophysiology 2014 Faggioni M, Savio-Galimberti E, Venkataraman R, Hwang HS, Kannankeril PJ, Darbar D, Knollmann BC
• Focal energy deprivation underlies arrhythmia susceptibility in mice with calcium-sensitized myofilaments.
  Circulation research 2013 Huke S, Venkataraman R, Faggioni M, Bennuri S, Hwang HS, Baudenbacher F, Knollmann BC
• Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients.
  Circulation research 2013 Faggioni M, Hwang HS, van der Werf C, Nederend I, Kannankeril PJ, Wilde AA, Knollmann BC
• Calsequestrin mutations and catecholaminergic polymorphic ventricular tachycardia.
  Pediatric cardiology 2012 Faggioni M, Kryshtal DO, Knollmann BC
• Calsequestrin 2 and arrhythmias.
  American journal of physiology. Heart and circulatory physiology 2011 Faggioni M, Knollmann BC
• Ferritin as a reporter gene for in vivo tracking of stem cells by 1.5-T cardiac MRI in a rat model of myocardial infarction.
  American journal of physiology. Heart and circulatory physiology 2011 Campan M, Lionetti V, Aquaro GD, Forini F, Matteucci M, Vannucci L, Chiuppesi F, Di Cristofano C, Faggioni M, Maioli M, Barile L, Messina E, Lombardi M, Pucci A, Pistello M, Recchia FA
• Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.
  Circulation. Arrhythmia and electrophysiology 2011 Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC