Michel Tassetto, PhD
Specialist
Microbiology and Immunology
School of Medicine

Education & Training

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• Postdoctoral Studies Graduate Division University of California, San Francisco

Publications (21)

Top publication keywords:
RNA InterferenceRNA VirusesDrosophila melanogasterRNA, Small InterferingSindbis VirusEctromelia virusEctromelia, InfectiousArgonaute ProteinsZea maysImmunity, InnateRNA, ViralTobamovirusHemocytesPoxviridaeAedes

• SARS-CoV-2 Nsp1 cooperates with initiation factors EIF1 and 1A to selectively enhance translation of viral RNA.
  PLoS pathogens 2024 Aviner R, Lidsky PV, Xiao Y, Tassetto M, Kim D, Zhang L, McAlpine PL, Elias J, Frydman J, Andino R
• Viral Determinants of Acute COVID-19 Symptoms in a Nonhospitalized Adult Population in the Pre-Omicron Era.
  Open forum infectious diseases 2023 Goldberg SA, Lu S, Garcia-Knight M, Davidson MC, Tassetto M, Anglin K, Pineda-Ramirez J, Chen JY, Rugart PR, Mathur S, Forman CA, Donohue KC, Abedi GR, Saydah S, Briggs-Hagen M, Midgley CM, Andino R, …
• Longitudinal and quantitative fecal shedding dynamics of SARS-CoV-2, pepper mild mottle virus, and crAssphage.
  mSphere 2023 Arts PJ, Kelly JD, Midgley CM, Anglin K, Lu S, Abedi GR, Andino R, Bakker KM, Banman B, Boehm AB, Briggs-Hagen M, Brouwer AF, Davidson MC, Eisenberg MC, Garcia-Knight M, Knight S, Peluso MJ, Pineda-…
• Association of Culturable-Virus Detection and Household Transmission of SARS-CoV-2, California and Tennessee, 2020-2022.
  The Journal of infectious diseases 2023 Deyoe JE, Kelly JD, Grijalva CG, Bonenfant G, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Hagen MB, Saydah S, Abedi GR, Goldberg SA, Tassetto M, Zhang A, Donohue KC, Davidson MC, Sanchez RD, …
• Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2.
  Nature microbiology 2023 Yang J, Xiao Y, Lidsky PV, Wu CT, Bonser LR, Peng S, Garcia-Knight MA, Tassetto M, Chung CI, Li X, Nakayama T, Lee IT, Nayak JV, Ghias K, Hargett KL, Shoichet BK, Erle DJ, Jackson PK, Andino R, Shu X

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• Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes.
  Cell reports 2022 Melo-Silva CR, Roman MI, Knudson CJ, Tang L, Xu RH, Tassetto M, Dolan P, Andino R, Sigal LJ
• Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in the Blood as a Diagnostic Test for Infection and Infectious Viral Shedding.
  Open forum infectious diseases 2022 Mathur S, Davidson MC, Anglin K, Lu S, Goldberg SA, Garcia-Knight M, Tassetto M, Zhang A, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Chen JY, Donohue K, Shak JR, Chenna A, Winslow JW, …
• Magnitude and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission: A Longitudinal Cohort Study.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Kelly JD, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Goldberg SA, Tassetto M, Zhang A, Donohue K, Davidson MC, Romero M, Diaz Sanchez R, Djomaleu M, Mathur S, Chen JY, Forman CA, Servellita V,…
• Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study.
  PLoS pathogens 2022 Garcia-Knight M, Anglin K, Tassetto M, Lu S, Zhang A, Goldberg SA, Catching A, Davidson MC, Shak JR, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Donohue K, Massachi J, Sans HM, Djomaleu M, …
• Detection of Higher Cycle Threshold Values in Culturable SARS-CoV-2 Omicron BA.1 Sublineage Compared with Pre-Omicron Variant Specimens - San Francisco Bay Area, California, July 2021-March 2022.
  MMWR. Morbidity and mortality weekly report 2022 Tassetto M, Garcia-Knight M, Anglin K, Lu S, Zhang A, Romero M, Pineda-Ramirez J, Sanchez RD, Donohue KC, Pfister K, Chan C, Saydah S, Briggs-Hagen M, Peluso MJ, Martin JN, Andino R, Midgley CM, Kelly…
• Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.
  Cell stem cell 2020 Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W,…
• Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements.
  eLife 2019 Tassetto M, Kunitomi M, Whitfield ZJ, Dolan PT, Sánchez-Vargas I, Garcia-Knight M, Ribiero I, Chen T, Olson KE, Andino R
• Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
  Cell 2018 Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E,…
• The Diversity, Structure, and Function of Heritable Adaptive Immunity Sequences in the Aedes aegypti Genome.
  Current biology : CB 2017 Whitfield ZJ, Dolan PT, Kunitomi M, Tassetto M, Seetin MG, Oh S, Heiner C, Paxinos E, Andino R
• Circulating Immune Cells Mediate a Systemic RNAi-Based Adaptive Antiviral Response in Drosophila.
  Cell 2017 Tassetto M, Kunitomi M, Andino R
• RNA interference-mediated intrinsic antiviral immunity in invertebrates.
  Current topics in microbiology and immunology 2013 Nayak A, Tassetto M, Kunitomi M, Andino R
• Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila.
  Nature structural & molecular biology 2010 Nayak A, Berry B, Tassetto M, Kunitomi M, Acevedo A, Deng C, Krutchinsky A, Gross J, Antoniewski C, Andino R
• Antiviral immunity in Drosophila requires systemic RNA interference spread.
  Nature 2009 Saleh MC, Tassetto M, van Rij RP, Goic B, Gausson V, Berry B, Jacquier C, Antoniewski C, Andino R
• Transcriptional control of dendritic patterning in Drosophila neurons.
  Genome biology 2006 Tassetto M, Gao FB
• Plant and animal homeodomains use convergent mechanisms for intercellular transfer.
  EMBO reports 2005 Tassetto M, Maizel A, Osorio J, Joliot A
• Engrailed homeoprotein secretion is a regulated process.
  Development (Cambridge, England) 2002 Maizel A, Tassetto M, Filhol O, Cochet C, Prochiantz A, Joliot A