Michaela West, MD, PhD
Professor Emeritus
Surgery
School of Medicine

Websites

Show all (1) Hide

• Google Scholar Profile (scholar.google.com)

Grants and Projects

Show all (4) Hide

• Inflammation and the Host Responses to Injury, NIH, 2000-2013
• Regulation of Macrophage Function in Surgical Sepsis, NIH, 1990-2010
• Regulation of Macrophage Function in Surgical Sepsis, NIH, 1990-1995
• Immunomodulatory Agents in the Treatment of Peritonitis, NIH, 1985

Publications (151)

Top publication keywords:
LipopolysaccharidesWounds, NonpenetratingShock, HemorrhagicRib FracturesBlood Component TransfusionSystemic Inflammatory Response SyndromeBurnsMacrophages, PeritonealAbscessWounds and InjuriesMultiple Organ FailureEndotoxinsBullyingPrisonsGeneral Surgery

• Lofty goals and strategic plans are not enough to achieve and maintain a diverse workforce: an American Association for the Surgery of Trauma Diversity, Equity, and Inclusion Committee conversation.
  Trauma surgery & acute care open 2021 Brasel K, Berry C, Williams BH, Henry SM, Upperman J, West MA
• Ensuring Equity, Diversity, and Inclusion in Academic Surgery: An American Surgical Association White Paper.
  Annals of surgery 2018 West MA, Hwang S, Maier RV, Ahuja N, Angelos P, Bass BL, Brasel KJ, Chen H, Davis KA, Eberlein TJ, Fong Y, Greenberg CC, Lillemoe KD, McCarthy MC, Michelassi F, Numann PJ, Parangi S, Reyes JD, Sanfey …
• Trial of short-course antimicrobial therapy for intraabdominal infection.
  The New England journal of medicine 2015 Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent …
• Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.
  Annals of surgery 2012 Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, …
• Mechanism of decreased in vitro murine macrophage cytokine release after exposure to carbon dioxide: relevance to laparoscopic surgery.
  Annals of surgery 1997 West MA, Hackam DJ, Baker J, Rodriguez JL, Bellingham J, Rotstein OD

Show all (146 more) Hide

• Use of an Integrated Pulmonary Index pathway decreased unplanned ICU admissions in elderly patients with rib fractures.
  Trauma surgery & acute care open 2024 Davis N, Lindbloom P, Hromatka K, Gipson J, West MA
• Impact of catastrophic brain injury guidelines on organ donation rates: Results of an EAST multicenter trial.
  The journal of trauma and acute care surgery 2024 Nordham KD, Tatum D, Attia AS, Patel MB, Paramesh A, Duchesne JC, Nahmias J, Maiga AW, Peetz AB, Udekwu PO, Stiles A, Shell C, Stodghill JD, Maghsoudi T, Iacullo E, McLafferty B, Coonan E, Boudreau RM…
• No benefit from the addition of low-dose ketamine infusion to standard evidence-based care of patients with multiple rib fractures.
  The journal of trauma and acute care surgery 2024 Macheel C, Farhat J, Gipson J, Lindbloom P, West MA
• Pooled Analysis of Trauma Centers Better Predicts Risk Factors for Firearm Violence Reinjury.
  The Journal of surgical research 2024 Lumbard DC, West MA, Cich IR, Hassan S, Shankar S, Nygaard RM
• A Look at Surgical Care in a State Correctional System-Unique and Informative but Incomplete.
  JAMA surgery 2024 West MA
• Current use and utility of magnetic resonance cholangiopancreatography, endoscopic retrograde cholangiopancreatography, and pancreatic duct stents: A secondary analysis from the Western Trauma Association multicenter trials group on pancreatic injuries.
  The journal of trauma and acute care surgery 2023 Biffl WL, Ball CG, Moore EE, West M, Russo RM, Balogh ZJ, Kornblith L, Castelo M, WTA Multicenter Trials Group on Pancreatic Injuries
• Invited Commentary: Long term Impact of Day Only Skin Abscess Protocol in a Tertiary Institution.
  World journal of surgery 2023 West MA
• A comparison of management and outcomes following blunt versus penetrating pancreatic trauma: A secondary analysis from the Western Trauma Association Multicenter Trials Group on Pancreatic Injuries.
  The journal of trauma and acute care surgery 2022 Biffl WL, Ball CG, Moore EE, West M, Russo RM, Balogh Z, Kornblith L, Callcut R, Schaffer KB, Castelo M, WTA Multicenter Trials Group on Pancreatic Injuries
• Discrimination, Harassment, and Bullying Is Reported to Be High by LGBTQ+ Surgical Residents.
  JAMA surgery 2022 West MA
• A simple improvised prehospital method to warm intravenous fluid.
  Journal of the American College of Emergency Physicians open 2021 Lyng JW, Perlmutter MC, West MA
• Invited Commentary: An Updated Overview of Gender Dysphoria and Gender Affirmation Surgery: What Every Plastic Surgeon Should Know.
  World journal of surgery 2021 West MA
• A multicenter trial of current trends in the diagnosis and management of high-grade pancreatic injuries.
  The journal of trauma and acute care surgery 2021 Biffl WL, Zhao FZ, Morse B, McNutt M, Lees J, Byerly S, Weaver J, Callcut R, Ball CG, Nahmias J, West M, Jurkovich GJ, Todd SR, Bala M, Spalding C, Kornblith L, Castelo M, Schaffer KB, Moore EE, WTA …
• Clinical Decision Support Intervention and Time to Imaging in Older Patients with Traumatic Brain Injury.
  Journal of the American College of Surgeons 2020 Nguyen AS, Yang S, Thielen BV, Techar K, Lorenzo RM, Berg C, Palmer C, Gipson JL, West MA, Tignanelli CJ
• Clinical Decision Support Intervention for Rib Fracture Treatment.
  Journal of the American College of Surgeons 2020 Macheel C, Reicks P, Sybrant C, Evans C, Farhat J, West MA, Tignanelli CJ
• Implementation of a Prophylactic Anticoagulation Guideline for Patients with Traumatic Brain Injury.
  Joint Commission journal on quality and patient safety 2019 Tignanelli CJ, Gipson J, Nguyen A, Martinez R, Yang S, Reicks PL, Sybrant C, Roach R, Thorson M, West MA
• Use of a Statewide Public Health Tool to Estimate Miles Driven by Intoxicated Drivers.
  JAMA surgery 2019 West MA, Smith A, Helm T, Reicks P, Thorson M, Gipson J
• The why and how our trauma patients die: A prospective Multicenter Western Trauma Association study.
  The journal of trauma and acute care surgery 2019 Callcut RA, Kornblith LZ, Conroy AS, Robles AJ, Meizoso JP, Namias N, Meyer DE, Haymaker A, Truitt MS, Agrawal V, Haan JM, Lightwine KL, Porter JM, San Roman JL, Biffl WL, Hayashi MS, Sise MJ, Badiee …
• Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries.
  The journal of trauma and acute care surgery 2018 Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto …
• Does Isolation of Enterococcus Affect Outcomes in Intra-Abdominal Infections?
  Surgical infections 2017 Sanders JM, Tessier JM, Sawyer R, Dellinger EP, Miller PR, Namias N, West MA, Cook CH, O'Neill PJ, Napolitano L, Rattan R, Cuschieri J, Claridge JA, Guidry CA, Askari R, Banton K, Rotstein O, Moore BJ…
• Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection.
  The American surgeon 2016 Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K…
• Harnessing demographic differences in organizations: What moderates the effects of workplace diversity?
  Journal of organizational behavior 2015 Guillaume YR, Dawson JF, Otaye-Ebede L, Woods SA, West MA
• Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma.
  Annals of surgery 2015 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Development and psychometric evaluation of a new team effectiveness scale for all types of community adult mental health teams: a mixed-methods approach.
  Health & social care in the community 2015 El Ansari W, Lyubovnikova J, Middleton H, Dawson JF, Naylor PB, West MA
• Remote inflammatory and metabolic impact of acute injury.
  Critical care medicine 2014 West MA
• What's new in shock? May 2014.
  Shock (Augusta, Ga.) 2014 West MA
• Western Trauma Association critical decisions in trauma: evaluation and management of peripheral vascular injury, part II.
  The journal of trauma and acute care surgery 2013 Feliciano DV, Moore EE, West MA, Moore FA, Davis JW, Cocanour CS, Scalea TM, McIntyre RC
• Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis.
  The journal of trauma and acute care surgery 2013 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Genomic responses in mouse models poorly mimic human inflammatory diseases.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, …
• Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix.
  The journal of trauma and acute care surgery 2012 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Shifting surgical paradigms for cholecystectomy in mild gallstone pancreatitis: comment on "early laparoscopic cholecystectomy for mild gallstone pancreatitis".
  Archives of surgery (Chicago, Ill. : 1960) 2012 West MA
• Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion.
  The journal of trauma and acute care surgery 2012 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cushieri J, Sperry JL, Inflammation and Host Response to Injury Investigators
• The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock.
  Critical care medicine 2012 Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• Trauma.
  Current opinion in critical care 2011 West MA
• A genomic storm in critically injured humans.
  The Journal of experimental medicine 2011 Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker…
• Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study.
  PLoS medicine 2011 Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD, Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program
• Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury.
  The Journal of trauma 2011 Brakenridge SC, Phelan HA, Henley SS, Golden RM, Kashner TM, Eastman AE, Sperry JL, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators
• Western Trauma Association/critical decisions in trauma: operative management of adult blunt hepatic trauma.
  The Journal of trauma 2011 Kozar RA, Feliciano DV, Moore EE, Moore FA, Cocanour CS, West MA, Davis JW, McIntyre RC
• Evaluation and management of peripheral vascular injury. Part 1. Western Trauma Association/critical decisions in trauma.
  The Journal of trauma 2011 Feliciano DV, Moore FA, Moore EE, West MA, Davis JW, Cocanour CS, Kozar RA, McIntyre RC
• Acute traumatic coagulopathy: from endogenous acute coagulopathy to systemic acquired coagulopathy and back.
  The Journal of trauma 2011 Cohen MJ, West M
• Human transcriptome array for high-throughput clinical studies.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W, Inflammation and Host …
• Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.
  The Journal of trauma 2011 Edmonds RD, Cuschieri J, Minei JP, Rosengart MR, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Sperry JL, Inflammation the Host Response to Injury Investigators
• Identification and interpretation of longitudinal gene expression changes in trauma.
  PloS one 2010 Rajicic N, Cuschieri J, Finkelstein DM, Miller-Graziano CL, Hayden D, Moldawer LL, Moore E, O'Keefe G, Pelik K, Warren HS, Schoenfeld DA, Inflammation and the Host Response to Injury Large Scale …
• Team working in intensive care: current evidence and future endeavors.
  Current opinion in critical care 2010 Richardson J, West MA, Cuthbertson BH
• Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure.
  Shock (Augusta, Ga.) 2010 Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV, Inflammation and the Host Response to Injury Collaborative …
• Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.
  Journal of proteome research 2010 Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Inflammation and the Host …
• Governors' Committee on Surgical Infections and Environmental Risks: an update.
  Bulletin of the American College of Surgeons 2010 West MA
• Clinical microfluidics for neutrophil genomics and proteomics.
  Nature medicine 2010 Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, …
• Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans.
  The Journal of trauma 2010 Cohen MJ, Carles M, Brohi K, Calfee CS, Rahn P, Call MS, Chesebro BB, West MA, Pittet JF
• Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
  Proceedings of the National Academy of Sciences of the United States of America 2010 Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Inflammation and Host Response to Injury Program, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan…
• Western Trauma Association critical decisions in trauma: screening for and treatment of blunt cerebrovascular injuries.
  The Journal of trauma 2009 Biffl WL, Cothren CC, Moore EE, Kozar R, Cocanour C, Davis JW, McIntyre RC, West MA, Moore FA
• Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury.
  Annals of surgery 2009 Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV
• Analysis of the relationship between longitudinal gene expressions and ordered categorical event data.
  Statistics in medicine 2009 Rajicic N, Finkelstein DM, Schoenfeld DA, Inflammation and Host Response to Injury Research Program Investigators
• Preinjury statin use is associated with a higher risk of multiple organ failure after injury: a propensity score adjusted analysis.
  The Journal of trauma 2009 Neal MD, Cushieri J, Rosengart MR, Alarcon LH, Moore EE, Maier RV, Minei JP, Billiar TR, Peitzman AB, Sperry JL, Inflammation and Host Response to Injury Investigators
• Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.
  The Journal of trauma 2009 Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB, Inflammation and Host Response to Injury Investigators
• Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients.
  The Journal of trauma 2009 Evans HL, Cuschieri J, Moore EE, Shapiro MB, Nathens AB, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, West MA, Inflammation and Host Response to Injury Investigators
• Assessing statistical significance in microarray experiments using the distance between microarrays.
  PloS one 2009 Hayden D, Lazar P, Schoenfeld D, Inflammation and the Host Response to Injury Investigators
• A genomic score prognostic of outcome in trauma patients.
  Molecular medicine (Cambridge, Mass.) 2009 Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, …
• Does splenectomy protect against immune-mediated complications in blunt trauma patients?
  Molecular medicine (Cambridge, Mass.) 2009 Crandall M, Shapiro MB, West MA
• Characterization of persistent hyperglycemia: what does it mean postinjury?
  The Journal of trauma 2009 Sperry JL, Frankel HL, Nathens AB, O'keefe GE, Cuschieri J, Moore EE, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators
• Acute uncomplicated appendicitis: case time of day influences hospital length of stay.
  Surgical infections 2009 Crandall M, Shapiro MB, Worley M, West MA
• Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample.
  Journal of proteome research 2009 Qian WJ, Liu T, Petyuk VA, Gritsenko MA, Petritis BO, Polpitiya AD, Kaushal A, Xiao W, Finnerty CC, Jeschke MG, Jaitly N, Monroe ME, Moore RJ, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, …
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients.
  The Journal of trauma 2008 West MA, Moore EE, Shapiro MB, Nathens AB, Cuschieri J, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VIII--Nutritional support of the trauma patient.
  The Journal of trauma 2008 O'Keefe GE, Shelton M, Cuschieri J, Moore EE, Lowry SF, Harbrecht BG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion.
  The Journal of trauma 2008 Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE, Inflammation the Host Response to Injury Investigators
• Western Trauma Association (WTA) critical decisions in trauma: management of adult blunt splenic trauma.
  The Journal of trauma 2008 Moore FA, Davis JW, Moore EE, Cocanour CS, West MA, McIntyre RC
• Western trauma association critical decisions in trauma: foreword.
  The Journal of trauma 2008 McIntyre RC, Moore FA, Davis JW, Cocanour CS, West MA, Moore EE
• Western trauma association critical decisions in trauma: management of pelvic fracture with hemodynamic instability.
  The Journal of trauma 2008 Davis JW, Moore FA, McIntyre RC, Cocanour CS, Moore EE, West MA
• Endotoxin tolerance in sepsis: concentration-dependent augmentation or inhibition of LPS-stimulated macrophage TNF secretion by LPS pretreatment.
  The Journal of trauma 2008 West MA, Koons A
• Temporal cytokine profiles in severely burned patients: a comparison of adults and children.
  Molecular medicine (Cambridge, Mass.) 2008 Finnerty CC, Jeschke MG, Herndon DN, Gamelli R, Gibran N, Klein M, Silver G, Arnoldo B, Remick D, Tompkins RG, Investigators of the Inflammation and the Host Response Glue Grant
• Abdominal compartment syndrome: a concise clinical review.
  Critical care medicine 2008 An G, West MA
• Even ephemeral endotoxin exposure establishes endotoxin tolerance.
  The Journal of trauma 2008 Koons A, Crandall M, An GC, Shapiro MB, Kramer S, West MA
• Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.
  Clinical chemistry 2008 Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins …
• Male gender is associated with excessive IL-6 expression following severe injury.
  The Journal of trauma 2008 Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, Remick DG, Minei JP, Inflammation and the Host Response to Injury Investigators
• Early use of vasopressors after injury: caution before constriction.
  The Journal of trauma 2008 Sperry JL, Minei JP, Frankel HL, West MA, Harbrecht BG, Moore EE, Maier RV, Nirula R
• Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice.
  Physiological genomics 2007 Lederer JA, Brownstein BH, Lopez MC, Macmillan S, Delisle AJ, Macconmara MP, Choudhry MA, Xiao W, Lekousi S, Cobb JP, Baker HV, Mannick JA, Chaudry IH, Inflammation and the Host Response to Injury …
• V. Guidelines for sedation and analgesia during mechanical ventilation general overview.
  The Journal of trauma 2007 Shapiro MB, West MA, Nathens AB, Harbrecht BG, Moore FA, Bankey PE, Freeman B, Johnson JL, McKinley BA, Minei JP, Moore EE, Maier RV, Inflammation and the Host Response to Injury Large Scale …
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient.
  The Journal of trauma 2007 Harbrecht BG, Minei JP, Shapiro MB, Nathens AB, Moore EE, West MA, Bankey PE, Cuschieri J, Johnson JL, Maier RV, Inflammation and the Host Response to Injury Scale Collaborative Research Project
• Whole blood leukocyte mitogen activated protein kinases activation differentiates intensive care unit patients with systemic inflammatory response syndrome and sepsis.
  The Journal of trauma 2007 West MA, Koons A, Crandall M, Skinner R, Worley M, Shapiro MB
• Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury.
  Journal of burn care & research : official publication of the American Burn Association 2007 Silver GM, Klein MB, Herndon DN, Gamelli RL, Gibran NS, Altstein L, McDonald-Smith GP, Tompkins RG, Hunt JL, Inflammation and the Host Response to Trauma, Collaborative Research Program
• The practice of venous thromboembolism prophylaxis in the major trauma patient.
  The Journal of trauma 2007 Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV
• Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Laudanski K, Miller-Graziano C, Xiao W, Mindrinos MN, Richards DR, De A, Moldawer LL, Maier RV, Bankey P, Baker HV, Brownstein BH, Cobb JP, Calvano SE, Davis RW, Tompkins RG
• Survival analysis of longitudinal microarrays.
  Bioinformatics (Oxford, England) 2006 Rajicic N, Finkelstein DM, Schoenfeld DA, Inflammation Host Response to Injury Research Program Investigators
• Evaluation of the abdomen in the critically ill patient: opening the black box.
  Current opinion in critical care 2006 Crandall M, West MA
• Inflammation and the host response to injury, a large-scale collaborative project: Patient-oriented research core-standard operating procedures for clinical care. IV. Guidelines for transfusion in the trauma patient.
  The Journal of trauma 2006 West MA, Shapiro MB, Nathens AB, Johnson JL, Moore EE, Minei JP, Bankey PE, Freeman B, Harbrecht BG, McKinley BA, Moore FA, Maier RV, Inflammation and the Host Response to Injury Collaborative …
• Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis.
  Analytical chemistry 2006 Sethu P, Moldawer LL, Mindrinos MN, Scumpia PO, Tannahill CL, Wilhelmy J, Efron PA, Brownstein BH, Tompkins RG, Toner M
• Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury.
  Journal of burn care & research : official publication of the American Burn Association 2006 Klein MB, Silver G, Gamelli RL, Gibran NS, Herndon DN, Hunt JL, Tompkins RG, Inflammation and the Host Response to Injury Investigators
• High dynamic range characterization of the trauma patient plasma proteome.
  Molecular & cellular proteomics : MCP 2006 Liu T, Qian WJ, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV, Davis RW, Tompkins RG, Camp DG, Smith RD, Inflammation and the Host Response to …
• Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury.
  Physiological genomics 2005 Brownstein BH, Logvinenko T, Lederer JA, Cobb JP, Hubbard WJ, Chaudry IH, Remick DG, Baker HV, Xiao W, Mannick JA
• Intestinal obstruction from furniture cushion foam bezoar.
  Surgery 2005 Chiu B, Ciaccio C, West MA
• Percutaneous endovascular repair of blunt thoracic aortic transection.
  The Journal of trauma 2005 Peterson BG, Matsumura JS, Morasch MD, West MA, Eskandari MK
• Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation.
  Journal of immunology (Baltimore, Md. : 1950) 2005 De AK, Miller-Graziano CL, Calvano SE, Laudanski K, Lowry SF, Moldawer LL, Remick DG, Rajicic N, Schoenfeld D, Tompkins RG
• A network-based analysis of systemic inflammation in humans.
  Nature 2005 Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, Inflamm and…
• Trauma clip-art: early experience with an improved radiopaque marker system for delineating the path of penetrating injuries.
  The Journal of trauma 2005 Peterson B, Shapiro MB, Crandall M, Skinner R, West MA
• Application of genome-wide expression analysis to human health and disease.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins …
• Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach.
  Molecular & cellular proteomics : MCP 2005 Qian WJ, Monroe ME, Liu T, Jacobs JM, Anderson GA, Shen Y, Moore RJ, Anderson DJ, Zhang R, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Camp DG, Smith RD, Inflammation and the …
• Acute inflammatory response to endotoxin in mice and humans.
  Clinical and diagnostic laboratory immunology 2005 Copeland S, Warren HS, Lowry SF, Calvano SE, Remick D, Inflammation and the Host Response to Injury Investigators
• Management of the critically ill patient with severe acute pancreatitis.
  Critical care medicine 2004 Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, Skerrett SJ, Stapleton RD, Ware LB, Waldmann CS
• Whole blood and leukocyte RNA isolation for gene expression analyses.
  Physiological genomics 2004 Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, Fay A, MacMillan S, Laramie J, Xiao W, Moldawer LL, Cobb JP, Laudanski K, Miller-Graziano CL, Maier RV, Schoenfeld D, Davis RW,…
• The importance of bactericidal drugs: future directions in infectious disease.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004 Finberg RW, Moellering RC, Tally FP, Craig WA, Pankey GA, Dellinger EP, West MA, Joshi M, Linden PK, Rolston KV, Rotschafer JC, Rybak MJ
• Executive summary: management of the critically ill patient with severe acute pancreatitis.
  Proceedings of the American Thoracic Society 2004 Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, Skerrett SJ, Stapleton RD, Ware LB, Waldmann CS
• Relative hyperoxia augments lipopolysaccharide-stimulated cytokine secretion by murine macrophages.
  Surgery 2003 Danielson DS, Heagy W, Nieman KM, West MA
• Evidence for a CD14- and serum-independent pathway in the induction of endotoxin-tolerance in human monocytes and THP-1 monocytic cells.
  Shock (Augusta, Ga.) 2003 Heagy W, Hansen C, Nieman K, West MA
• Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: a multicenter, prospective, randomized, open-label study.
  Clinical therapeutics 2003 West M, Boulanger BR, Fogarty C, Tennenberg A, Wiesinger B, Oross M, Wu SC, Fowler C, Morgan N, Kahn JB
• Knowledge and truth: answers or questions?
  Surgical infections 2003 West MA
• Lower levels of whole blood LPS-stimulated cytokine release are associated with poorer clinical outcomes in surgical ICU patients.
  Surgical infections 2003 Heagy W, Nieman K, Hansen C, Cohen M, Danielson D, West MA
• Society profiles. Interview by Vicki Glaser.
  Surgical infections 2003 West MA
• Ertapenem monotherapy versus combination therapy with ceftriaxone plus metronidazole for treatment of complicated intra-abdominal infections in adults.
  International journal of antimicrobial agents 2002 Yellin AE, Hassett JM, Fernandez A, Geib J, Adeyi B, Woods GL, Teppler H, 004 Intra-abdominal Infection Study Group
• Endotoxin tolerance: A review.
  Critical care medicine 2002 West MA, Heagy W
• Endotoxin tolerance: a review.
  Critical care medicine 2002 West MA, Heagy W
• Cytokines and the pathogenesis of nosocomial pneumonia.
  Surgery 2001 Muehlstedt SG, Richardson CJ, West MA, Lyte M, Rodriguez JL
• Recent developments in clinical management of surgical sepsis.
  Current opinion in critical care 2001 Danielson D, West MA
• The impact of managed care and current governmental policies on an urban academic health care center.
  Surgery 2001 Rodriguez JL, Peterson DJ, Muehlstedt SG, Zera RT, West MA, Bubrick MP
• Abdominal compartment syndrome in the intensive care unit.
  Current opinion in critical care 2001 Morken J, West MA
• Penetrating esophageal injuries: multicenter study of the American Association for the Surgery of Trauma.
  The Journal of trauma 2001 Asensio JA, Chahwan S, Forno W, MacKersie R, Wall M, Lake J, Minard G, Kirton O, Nagy K, Karmy-Jones R, Brundage S, Hoyt D, Winchell R, Kralovich K, Shapiro M, Falcone R, McGuire E, Ivatury R, Stoner …
• Impaired mitogen-activated protein kinase activation and altered cytokine secretion in endotoxin-tolerant human monocytes.
  The Journal of trauma 2000 Heagy W, Hansen C, Nieman K, Rodriguez JL, West MA
• Trauma in cirrhotics: survival and hospital sequelae in patients requiring abdominal exploration.
  The American surgeon 2000 Wahlstrom K, Ney AL, Jacobson S, Odland MD, Van Camp JM, Rodriguez JL, West MA
• Abdominal vena caval injuries: outcomes remain dismal.
  Surgery 2000 Hansen CJ, Bernadas C, West MA, Ney AL, Muehlstedt S, Cohen M, Rodriguez JL
• Academic practice groups: strategy for survival.
  Surgery 2000 Rodriguez JL, Jacobs DM, Zera RT, Van Camp JM, Muehlstedt SG, West MA, Bubrick MP
• Stapled versus hand sewn anastomoses in patients with small bowel injury: a changing perspective.
  The Journal of trauma 2000 Witzke JD, Kraatz JJ, Morken JM, Ney AL, West MA, Van Camp JM, Zera RT, Rodriguez JL
• Impaired ex vivo lipopolysaccharide-stimulated whole blood tumor necrosis factor production may identify "septic" intensive care unit patients.
  Shock (Augusta, Ga.) 2000 Heagy W, Hansen C, Nieman K, Cohen M, Richardson C, Rodriguez JL, West MA
• Defective lipopolysaccharide-dependent ERK 1/2 activation in endotoxin tolerant murine macrophages is reversed by direct protein kinase C stimulation.
  Shock (Augusta, Ga.) 2000 West MA, Clair L, Bellingham J, Wahlstrom K, Rodriguez JL
• Endotoxin tolerance from lipopolysaccharide pretreatment induces nuclear factor-kappaB alterations not present in C3H/HeJ mice.
  The Journal of trauma 2000 West MA, Clair L, Kraatz J, Rodriguez JL
• Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation.
  Current biology : CB 2000 West MA, Prescott AR, Eskelinen EL, Ridley AJ, Watts C
• Membrane ruffling, macropinocytosis and antigen presentation in the absence of gelsolin in murine dendritic cells.
  European journal of immunology 1999 West MA, Antoniou AN, Prescott AR, Azuma T, Kwiatkowski DJ, Watts C
• Civilian rectal trauma: a changing perspective.
  Surgery 1999 Morken JJ, Kraatz JJ, Balcos EG, Hill MJ, Ney AL, West MA, Van Camp JM, Zera RT, Jacobs DM, Odland MD, Rodriguez JL
• Trauma faculty and trauma team activation: impact on trauma system function and patient outcome.
  The Journal of trauma 1999 Khetarpal S, Steinbrunn BS, McGonigal MD, Stafford R, Ney AL, Kalb DC, West MA, Rodriguez JL
• Macrophage TNF secretion in endotoxin tolerance: role of SAPK, p38, and MAPK.
  The Journal of surgical research 1999 Kraatz J, Clair L, Rodriguez JL, West MA
• Wound management in perforated appendicitis.
  The American surgeon 1999 Lemieur TP, Rodriguez JL, Jacobs DM, Bennett ME, West MA
• Inhibitory kappaBalpha control of nuclear factor-kappaB is dysregulated in endotoxin tolerant macrophages.
  Shock (Augusta, Ga.) 1999 Wahlstrom K, Bellingham J, Rodriguez JL, West MA
• In vitro macrophage endotoxin tolerance: defective in vitro macrophage map kinase signal transduction after LPS pretreatment is not present in macrophages from C3H/HeJ endotoxin resistant mice.
  Shock (Augusta, Ga.) 1999 Kraatz J, Clair L, Rodriguez JL, West MA
• Acetazolamide treatment prevents in vitro endotoxin-stimulated tumor necrosis factor release in mouse macrophages.
  Shock (Augusta, Ga.) 1998 West MA, LeMieur TL, Hackam D, Bellingham J, Claire L, Rodriguez JL
• Assessment of the relationship between timing of fixation of the fracture and secondary brain injury in patients with multiple trauma.
  Surgery 1998 Kalb DC, Ney AL, Rodriguez JL, Jacobs DM, Van Camp JM, Zera RT, Rockswold GL, West MA
• Lipopolysaccharide pretreatment produces macrophage endotoxin tolerance via a serum-independent pathway.
  The Journal of trauma 1998 Kraatz J, Clair L, Bellingham J, Wahlstrom K, Rodriguez JL, West MA
• A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group.
  Archives of surgery (Chicago, Ill. : 1960) 1997 Barie PS, Vogel SB, Dellinger EP, Rotstein OD, Solomkin JS, Yang JY, Baumgartner TF
• Efficacy of radioprotective agents in preventing small and large bowel radiation injury.
  Diseases of the colon and rectum 1995 Carroll MP, Zera RT, Roberts JC, Schlafmann SE, Feeney DA, Johnston GR, West MA, Bubrick MP
• Current treatment recommendations for topical burn therapy.
  Drugs 1990 Monafo WW, West MA
• Modulation of Kupffer cell membrane phospholipid function by n-3 polyunsaturated fatty acids.
  The Journal of surgical research 1989 Bankey PE, Billiar TR, Wang WY, Carlson A, Holman RT, Cerra FB
• Hepatic dysfunction in multiple systems organ failure as a manifestation of altered cell-cell interaction.
  Progress in clinical and biological research 1989 Cerra FB, West M, Billiar TR, Holman RT, Simmons R
• Direct effects of endotoxin on hepatocytes. Synthesis of a specific secretory protein.
  Archives of surgery (Chicago, Ill. : 1960) 1988 Mazuski JE, Platt JL, West MA, Simmons RL, Towle HC, Cerra FB
• Hypermetabolism/organ failure: the role of the activated macrophage as a metabolic regulator.
  Progress in clinical and biological research 1988 Cerra FB, West M, Keller G, Mazuski J, Simmons RL
• Prostaglandin E2 mediates subset-specific effects on the functional responses of allosensitized T lymphocyte clones.
  Transplantation 1987 Jordan ML, Hoffman RA, Debe EF, West MA, Simmons RL
• Macrophage-mediated modulation of hepatocyte protein synthesis. Effect of dexamethasone.
  Archives of surgery (Chicago, Ill. : 1960) 1986 Keller GA, West MA, Cerra FB, Simmons RL
• Macrophage-mediated modulation of hepatic function in multiple-system failure.
  The Journal of surgical research 1985 Keller GA, West MA, Cerra FB, Simmons RL
• Killed Escherichia coli stimulates macrophage-mediated alterations in hepatocellular function during in vitro coculture: a mechanism of altered liver function in sepsis.
  Infection and immunity 1985 West MA, Keller GA, Cerra FB, Simmons RL
• Modulation of hepatocyte protein synthesis during co-cultivation with macrophage-rich peritoneal cells in vitro.
  Archives of surgery (Chicago, Ill. : 1960) 1985 Keller GA, West MA, Harty JT, Cerra FB, Simmons RL
• Multiple systems organ failure. Modulation of hepatocyte protein synthesis by endotoxin activated Kupffer cells.
  Annals of surgery 1985 Keller GA, West MA, Cerra FB, Simmons RL