Michael Rosenblum, MD, PhD
Professor
Dermatology
School of Medicine

One of the world's leading skin immunologists, Rosenblum's research has led to a better understanding of how immune responses are regulated in tissues. He also studies how to use this knowledge to develop better treatments for autoimmune disorders.

After completing a doctorate in immunology at the Medical College of Wisconsin, Rosenblum earned his medical degree from the same institution. He completed a residency in dermatology at UCSF.

Rosenblum is a member of the American Association of Immunologists, Society for Investigative Dermatology, American Academy of Dermatology and Federation of Clinical Immunology Societies. He has co-founded multiple biotech companies that are developing new treatments for autoimmune diseases.

• Interleukin-2-induced skin inflammation.
  European journal of immunology 2024 Sommer C, Cohen JN, Dehmel S, Neuhaus V, Schaudien D, Braun A, Sewald K, Rosenblum MD
• Tertiary lymphoid structures sustain cutaneous B cell activity in hidradenitis suppurativa.
  JCI insight 2024 Lowe MM, Cohen JN, Moss MI, Clancy S, Adler JP, Yates AE, Naik HB, Yadav R, Pauli M, Taylor I, McKay A, Harris H, Kim E, Hansen SL, Rosenblum MD, Moreau JM
• Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche.
  Science immunology 2024 Cohen JN, Gouirand V, Macon CE, Lowe MM, Boothby IC, Moreau JM, Gratz IK, Stoecklinger A, Weaver CT, Sharpe AH, Ricardo-Gonzalez RR, Rosenblum MD
• Tertiary Lymphoid Structures Sustain Cutaneous B cell Activity in Hidradenitis Suppurativa.
  bioRxiv : the preprint server for biology 2023 Lowe MM, Cohen JN, Moss MI, Clancy S, Adler J, Yates A, Naik HB, Pauli M, Taylor I, McKay A, Harris H, Kim E, Hansen SL, Rosenblum MD, Moreau JM
• Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy.
  JCI insight 2022 Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD
• Xenograft Skin Model to Manipulate Human Immune Responses In Vivo.
  Journal of visualized experiments : JoVE 2022 Moss MI, Pauli M, Moreau JM, Cohen JN, Rosenblum MD, Lowe MM
• Transforming growth factor-β1 in regulatory T cell biology.
  Science immunology 2022 Moreau JM, Velegraki M, Bolyard C, Rosenblum MD, Li Z
• MTHFD2, metabolic mastermind of CD4+ T cell destiny.
  Science immunology 2022 Gouirand V, Rosenblum MD
• Identifying and antagonizing the interactions between layilin and glycosylated collagens.
  Cell chemical biology 2022 Glasgow JE, Byrnes JR, Barbee SD, Moreau JM, Rosenblum MD, Wells JA
• Author Correction: Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin.
  Scientific reports 2022 Ahn RS, Taravati K, Lai K, Lee KM, Nititham J, Gupta R, Chang DS, Arron ST, Rosenblum M, Liao W
• Transcriptomic Profiling of Plaque Psoriasis and Cutaneous T-Cell Subsets during Treatment with Secukinumab.
  JID innovations : skin science from molecules to population health 2021 Liu J, Chang HW, Grewal R, Cummins DD, Bui A, Beck KM, Sekhon S, Yan D, Huang ZM, Schmidt TH, Yang EJ, Sanchez IM, Nakamura M, Bhattarai S, Thibodeaux Q, Ahn R, Pauli M, Bhutani T, Rosenblum MD, Liao …
• Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin.
  Nature 2021 Boothby IC, Kinet MJ, Boda DP, Kwan EY, Clancy S, Cohen JN, Habrylo I, Lowe MM, Pauli M, Yates AE, Chan JD, Harris HW, Neuhaus IM, McCalmont TH, Molofsky AB, Rosenblum MD
• Tregs and inflammation-bring it on!
  Science immunology 2021 Gouirand V, Rosenblum MD
• Layilin Anchors Regulatory T Cells in Skin.
  Journal of immunology (Baltimore, Md. : 1950) 2021 Mehta P, Gouirand V, Boda DP, Zhang J, Gearty SV, Zirak B, Lowe MM, Clancy S, Boothby I, Mahuron KM, Fries A, Krummel MF, Mankoo P, Chang HW, Liu J, Moreau JM, Scharschmidt TC, Daud A, Kim E, Neuhaus …
• Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation.
  Science immunology 2021 Moreau JM, Dhariwala MO, Gouirand V, Boda DP, Boothby IC, Lowe MM, Cohen JN, Macon CE, Leech JM, Kalekar LA, Scharschmidt TC, Rosenblum MD
• Regulatory T Cells and Inflammatory Mediators in Autoimmune Disease.
  The Journal of investigative dermatology 2021 Gouirand V, Habrylo I, Rosenblum MD
• Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy.
  Cell reports 2021 Dodagatta-Marri E, Ma HY, Liang B, Li J, Meyer DS, Chen SY, Sun KH, Ren X, Zivak B, Rosenblum MD, Headley MB, Pinzas L, Reed NI, Del Cid JS, Hann BC, Yang S, Giddabasappa A, Noorbehesht K, Yang B, Dal…
• T-Cell Adhesion in Healthy and Inflamed Skin.
  JID innovations : skin science from molecules to population health 2021 Moreau JM, Gouirand V, Rosenblum MD
• Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment.
  The Journal of experimental medicine 2021 Pauken KE, Shahid O, Lagattuta KA, Mahuron KM, Luber JM, Lowe MM, Huang L, Delaney C, Long JM, Fung ME, Newcomer K, Tsai KK, Chow M, Guinn S, Kuchroo JR, Burke KP, Schenkel JM, Rosenblum MD, Daud AI, …
• TregGF-β: Deletion of TGF-β in Tregs revisited.
  Science immunology 2021 Boothby IC, Rosenblum MD
• Histologic progression of acne inversa/hidradenitis suppurativa: Implications for future investigations and therapeutic intervention.
  Experimental dermatology 2021 Dunstan RW, Salte KM, Todorovic V, Lowe M, Wetter JB, Harms PW, Burney RE, Scott VE, Smith KM, Rosenblum MD, Gudjonsson JE, Honore P
• Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer.
  The Journal of allergy and clinical immunology 2020 Liu J, Chang HW, Huang ZM, Nakamura M, Sekhon S, Ahn R, Munoz-Sandoval P, Bhattarai S, Beck KM, Sanchez IM, Yang E, Pauli M, Arron ST, Fung-Leung WP, Munoz E, Liu X, Bhutani T, North J, Fourie AM, …
• Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
  Cell reports. Medicine 2020 Dhariwala MO, Karthikeyan D, Vasquez KS, Farhat S, Weckel A, Taravati K, Leitner EG, Clancy S, Pauli M, Piper ML, Cohen JN, Ashouri JF, Lowe MM, Rosenblum MD, Scharschmidt TC
• Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo.
  Journal of immunology (Baltimore, Md. : 1950) 2020 Pinheiro DF, Szenes-Nagy AB, Maurano MM, Lietzenmayer M, Klicznik MM, Holly R, Kirchmeier D, Kitzmueller S, Achatz-Straussberger G, Rosenblum MD, Thalhamer J, Abbas AK, Gratz IK
• Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis.
  JCI insight 2020 Gudjonsson JE, Tsoi LC, Ma F, Billi AC, van Straalen KR, Vossen ARJV, van der Zee HH, Harms PW, Wasikowski R, Yee CM, Rizvi SM, Xing X, Xing E, Plazyo O, Zeng C, Patrick MT, Lowe MM, Burney RE, Kozlow…
• Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy.
  JCI insight 2020 Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD
• Layilin augments integrin activation to promote antitumor immunity.
  The Journal of experimental medicine 2020 Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, …
• Keepin' it regulatory: Foxp3 gets a BAFfling SWItch.
  Science immunology 2020 Kinet MJ, Rosenblum MD
• Exhausted T cell signature predicts immunotherapy response in ER-positive breast cancer.
  Nature communications 2020 Terranova-Barberio M, Pawlowska N, Dhawan M, Moasser M, Chien AJ, Melisko ME, Rugo H, Rahimi R, Deal T, Daud A, Rosenblum MD, Thomas S, Munster PN
• A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin.
  Scientific reports 2020 Klicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK
• Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.
  Annals of surgical oncology 2020 Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI
• Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Algazi AP, Twitty CG, Tsai KK, Le M, Pierce R, Browning E, Hermiz R, Canton DA, Bannavong D, Oglesby A, Francisco M, Fong L, Pittet MJ, Arlauckas SP, Garris C, Levine LP, Bifulco C, Ballesteros-Merino…
• Regulatory T cells in skin injury: At the crossroads of tolerance and tissue repair.
  Science immunology 2020 Boothby IC, Cohen JN, Rosenblum MD
• Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair.
  Cell stem cell 2020 Shook BA, Wasko RR, Mano O, Rutenberg-Schoenberg M, Rudolph MC, Zirak B, Rivera-Gonzalez GC, López-Giráldez F, Zarini S, Rezza A, Clark DA, Rendl M, Rosenblum MD, Gerstein MB, Horsley V
• Sex drives Tregs into fat.
  Science immunology 2020 Habrylo I, Rosenblum MD
• Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues.
  JCI insight 2019 Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, Arron ST, Neuhaus IM, Harris HW, …
• An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease.
  Biomaterials 2019 Zamecnik CR, Levy ES, Lowe MM, Zirak B, Rosenblum MD, Desai TA
• Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses.
  Science immunology 2019 Kalekar LA, Cohen JN, Prevel N, Sandoval PM, Mathur AN, Moreau JM, Lowe MM, Nosbaum A, Wolters PJ, Haemel A, Boin F, Rosenblum MD
• Regulatory T cells in inflammatory skin disease: from mice to humans.
  International immunology 2019 Kalekar LA, Rosenblum MD
• Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals.
  Science immunology 2019 Klicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK
• CD27 Promotes CD4+ Effector T Cell Survival in Response to Tissue Self-Antigen.
  Journal of immunology (Baltimore, Md. : 1950) 2019 Remedios KA, Meyer L, Zirak B, Pauli ML, Truong HA, Boda D, Rosenblum MD
• Y'all comeback now.
  Science immunology 2019 Cohen JN, Rosenblum MD
• Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells.
  Cell 2019 Miao Y, Yang H, Levorse J, Yuan S, Polak L, Sribour M, Singh B, Rosenblum MD, Fuchs E
• Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair.
  Immunity 2019 Mathur AN, Zirak B, Boothby IC, Tan M, Cohen JN, Mauro TM, Mehta P, Lowe MM, Abbas AK, Ali N, Rosenblum MD
• α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.
  Journal for immunotherapy of cancer 2019 Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza …
• Adoptive Treg Cell Therapy in a Patient With Systemic Lupus Erythematosus.
  Arthritis & rheumatology (Hoboken, N.J.) 2019 Dall'Era M, Pauli ML, Remedios K, Taravati K, Sandova PM, Putnam AL, Lares A, Haemel A, Tang Q, Hellerstein M, Fitch M, McNamara J, Welch B, Bluestone JA, Wofsy D, Rosenblum MD, Autoimmunity Centers …
• Inflammatory T cells maintain a healing disposition.
  Science immunology 2019 Moreau JM, Rosenblum MD
• The TNFRSF members CD27 and OX40 coordinately limit TH17 differentiation in regulatory T cells.
  Science immunology 2018 Remedios KA, Zirak B, Sandoval PM, Lowe MM, Boda D, Henley E, Bhattrai S, Scharschmidt TC, Liao W, Naik HB, Rosenblum MD
• Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Emrick JJ, Mathur A, Wei J, Gracheva EO, Gronert K, Rosenblum MD, Julius D
• Colitis interruptus: LAGing gut inflammation.
  Science immunology 2018 Mehta P, Rosenblum MD
• Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization.
  Microbiome 2018 Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W
• RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways.
  Scientific reports 2018 Ahn R, Yan D, Chang HW, Lee K, Bhattarai S, Huang ZM, Nakamura M, Singh R, Afifi L, Taravati K, Munoz-Sandoval P, Pauli M, Rosenblum MD, Liao W
• A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
  Nature medicine 2018 Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, …
• Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.
  Cell reports 2018 Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage M
• Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.
  The Journal of clinical investigation 2018 Mande P, Zirak B, Ko WC, Taravati K, Bride KL, Brodeur TY, Deng A, Dresser K, Jiang Z, Ettinger R, Fitzgerald KA, Rosenblum MD, Harris JE, Marshak-Rothstein A
• Say it isn't pso: IL-25 drives skin inflammation.
  Science immunology 2018 Kalekar LA, Rosenblum MD
• Skin-Resident T Cells Drive Dermal Dendritic Cell Migration in Response to Tissue Self-Antigen.
  Journal of immunology (Baltimore, Md. : 1950) 2018 Ali N, Zirak B, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD
• SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.
  The journal of allergy and clinical immunology. In practice 2018 White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH, Hung SI, Lacouture ME, Lehloenya RJ, …
• HDAC inhibition potentiates immunotherapy in triple negative breast cancer.
  Oncotarget 2017 Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN
• Genomic analysis of atypical fibroxanthoma.
  PloS one 2017 Lai K, Harwood CA, Purdie KJ, Proby CM, Leigh IM, Ravi N, Mully TW, Brooks L, Sandoval PM, Rosenblum MD, Arron ST
• Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators.
  ACS nano 2017 Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA
• Chronic Helicobacter cinaedi cellulitis diagnosed by microbial polymerase chain reaction.
  JAAD case reports 2017 Matsumoto A, Yeh I, Schwartz B, Rosenblum M, Schmidt TH
• Regulatory T cells in skin.
  Immunology 2017 Ali N, Rosenblum MD
• Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy.
  JCI insight 2017 Loo K, Tsai KK, Mahuron K, Liu J, Pauli ML, Sandoval PM, Nosrati A, Lee J, Chen L, Hwang J, Levine LS, Krummel MF, Algazi AP, Pampaloni M, Alvarado MD, Rosenblum MD, Daud AI
• Skin-infiltrating, interleukin-22-producing T cells differentiate pediatric psoriasis from adult psoriasis.
  Journal of the American Academy of Dermatology 2017 Cordoro KM, Hitraya-Low M, Taravati K, Sandoval PM, Kim E, Sugarman J, Pauli ML, Liao W, Rosenblum MD
• Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.
  Cell 2017 Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, …
• Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin.
  Scientific reports 2017 Ahn RS, Taravati K, Lai K, Lee KM, Nititham J, Gupta R, Chang DS, Arron ST, Rosenblum M, Liao W
• Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC.
  Cancer immunology research 2017 Tumeh PC, Hellmann MD, Hamid O, Tsai KK, Loo KL, Gubens MA, Rosenblum M, Harview CL, Taube JM, Handley N, Khurana N, Nosrati A, Krummel MF, Tucker A, Sosa EV, Sanchez PJ, Banayan N, Osorio JC, Nguyen-…
• Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.
  Cell host & microbe 2017 Scharschmidt TC, Vasquez KS, Pauli ML, Leitner EG, Chu K, Truong HA, Lowe MM, Sanchez Rodriguez R, Ali N, Laszik ZG, Sonnenburg JL, Millar SE, Rosenblum MD
• Warfarin-Associated Nonuremic Calciphylaxis.
  JAMA dermatology 2017 Yu WY, Bhutani T, Kornik R, Pincus LB, Mauro T, Rosenblum MD, Fox LP
• Response to Interleukin (IL)-17 Inhibition in an Adolescent With Severe Manifestations of IL-36 Receptor Antagonist Deficiency (DITRA).
  JAMA dermatology 2017 Cordoro KM, Ucmak D, Hitraya-Low M, Rosenblum MD, Liao W
• Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma.
  The Journal of clinical investigation 2016 Daud AI, Loo K, Pauli ML, Sanchez-Rodriguez R, Sandoval PM, Taravati K, Tsai K, Nosrati A, Nardo L, Alvarado MD, Algazi AP, Pampaloni MH, Lobach IV, Hwang J, Pierce RH, Gratz IK, Krummel MF, Rosenblum…
• Plasmacytoid dendritic cells (pDCs) and regulatory T (Treg) cells may be the key to viral reactivation in drug-induced hypersensitivity syndrome (DIHS).
  Journal of the American Academy of Dermatology 2016 Chen YC, Rosenblum MD, Shinkai K
• Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing.
  Journal of immunology (Baltimore, Md. : 1950) 2016 Nosbaum A, Prevel N, Truong HA, Mehta P, Ettinger M, Scharschmidt TC, Ali NH, Pauli ML, Abbas AK, Rosenblum MD
• The distribution of cutaneous metastases correlates with local immunologic milieu.
  Journal of the American Academy of Dermatology 2016 Schulman JM, Pauli ML, Neuhaus IM, Sanchez Rodriguez R, Taravati K, Shin US, McCalmont TH, Rosenblum MD
• Regulatory T cell memory.
  Nature reviews. Immunology 2015 Rosenblum MD, Way SS, Abbas AK
• A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes.
  Immunity 2015 Scharschmidt TC, Vasquez KS, Truong HA, Gearty SV, Pauli ML, Nosbaum A, Gratz IK, Otto M, Moon JJ, Liese J, Abbas AK, Fischbach MA, Rosenblum MD
• Mechanisms of human autoimmunity.
  The Journal of clinical investigation 2015 Rosenblum MD, Remedios KA, Abbas AK
• COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.
  Nature genetics 2015 Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas …
• Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.
  Cancer cell 2014 Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF
• Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.
  Cancer cell 2014 Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF
• Melanoma immunotherapy.
  Cancer biology & therapy 2014 Sanlorenzo M, Vujic I, Posch C, Dajee A, Yen A, Kim S, Ashworth M, Rosenblum MD, Algazi A, Osella-Abate S, Quaglino P, Daud A, Ortiz-Urda S
• A case of Wong-type dermatomyositis with concomitant anti-MDA5 features.
  Journal of the American Academy of Dermatology 2014 Canavan T, Sidorsky T, Doan LT, Ricardo-Gonzalez RR, Shen G, Rosenblum MD
• Plaque-based sub-blistering dosimetry: Reaching PASI-75 after two treatments with 308-nm excimer laser in a generalized psoriasis patient.
  The Journal of dermatological treatment 2014 Debbaneh MG, Levin E, Sanchez Rodriguez R, Leon A, Koo J, Rosenblum MD
• Memory regulatory T cells reside in human skin.
  The Journal of clinical investigation 2014 Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, …
• Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues.
  Journal of immunology (Baltimore, Md. : 1950) 2014 Gratz IK, Rosenblum MD, Maurano MM, Paw JS, Truong HA, Marshak-Rothstein A, Abbas AK
• An open-label study of anakinra for the treatment of moderate to severe hidradenitis suppurativa.
  Journal of the American Academy of Dermatology 2013 Leslie KS, Tripathi SV, Nguyen TV, Pauli M, Rosenblum MD
• Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.
  Journal of immunology (Baltimore, Md. : 1950) 2013 Callahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A
• Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.
  The Journal of clinical investigation 2013 Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R
• Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues.
  Journal of immunology (Baltimore, Md. : 1950) 2013 Gratz IK, Truong HA, Yang SH, Maurano MM, Lee K, Abbas AK, Rosenblum MD
• The life of regulatory T cells.
  Annals of the New York Academy of Sciences 2013 Gratz IK, Rosenblum MD, Abbas AK
• In vivo cardiac phase response curve elucidates human respiratory heart rate variability.
  Nature communications 2013 Kralemann B, Frühwirth M, Pikovsky A, Rosenblum M, Kenner T, Schaefer J, Moser M
• Treating human autoimmunity: current practice and future prospects.
  Science translational medicine 2012 Rosenblum MD, Gratz IK, Paw JS, Abbas AK
• Response to self antigen imprints regulatory memory in tissues.
  Nature 2011 Rosenblum MD, Gratz IK, Paw JS, Lee K, Marshak-Rothstein A, Abbas AK
• Erosive pustular dermatosis of the scalp: a review with a focus on dapsone therapy.
  Journal of the American Academy of Dermatology 2011 Broussard KC, Berger TG, Rosenblum M, Murase JE
• Opposing functions of IL-2 and IL-7 in the regulation of immune responses.
  Cytokine 2011 Katzman SD, Hoyer KK, Dooms H, Gratz IK, Rosenblum MD, Paw JS, Isakson SH, Abbas AK
• The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapy.
  PloS one 2009 Rosenblum M, Deeks SG, van der Laan M, Bangsberg DR
• Phase II study of intraperitoneal recombinant interleukin-12 (rhIL-12) in patients with peritoneal carcinomatosis (residual disease < 1 cm) associated with ovarian cancer or primary peritoneal carcinoma.
  Journal of translational medicine 2007 Lenzi R, Edwards R, June C, Seiden MV, Garcia ME, Rosenblum M, Freedman RS
• CD200, a "no danger" signal for hair follicles.
  Journal of dermatological science 2006 Rosenblum MD, Yancey KB, Olasz EB, Truitt RL
• Characterization of CD 200-receptor expression in the murine epidermis.
  The Journal of investigative dermatology 2005 Rosenblum MD, Woodliff JE, Madsen NA, McOlash LJ, Keller MR, Truitt RL
• Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?
  The Journal of investigative dermatology 2004 Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL
• Efficacy of alemtuzumab treatment for refractory T-cell large granular lymphocytic leukemia.
  Blood 2004 Rosenblum MD, LaBelle JL, Chang CC, Margolis DA, Schauer DW, Vesole DH
• CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance.
  Blood 2003 Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL
• Concurrent presence of both patient and donor t(14;18) in a follicular lymphoma patient after undergoing allogeneic BMT: implications for minimal residual disease detection post-transplant.
  Bone marrow transplantation 2003 Rosenblum MD, Drobyski WR, Keever-Taylor C, Chang CC
• Subcutaneous plasmacytomas with tropism to sites of previous trauma in a multiple myeloma patient treated with an autologous bone marrow transplant.
  American journal of hematology 2003 Rosenblum MD, Bredeson CN, Chang CC, Rizzo JD
• Phase I study of intraperitoneal recombinant human interleukin 12 in patients with Müllerian carcinoma, gastrointestinal primary malignancies, and mesothelioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2002 Lenzi R, Rosenblum M, Verschraegen C, Kudelka AP, Kavanagh JJ, Hicks ME, Lang EA, Nash MA, Levy LB, Garcia ME, Platsoucas CD, Abbruzzese JL, Freedman RS
• 'Rings' of F-actin form around the nucleus in cultured human MCF7 adenocarcinoma cells upon exposure to both taxol and taxotere.
  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2000 Rosenblum MD, Shivers RR
• Regimen-related toxicity of myeloablative chemotherapy with BCNU, thiotepa, and etoposide followed by autologous stem cell rescue for children with newly diagnosed glioblastoma multiforme: report from the Children's Cancer Group.
  Medical and pediatric oncology 1999 Grovas AC, Boyett JM, Lindsley K, Rosenblum M, Yates AJ, Finlay JL
• Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumors.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Guruangan S, Dunkel IJ, Goldman S, Garvin JH, Rosenblum M, Boyett JM, Gardner S, Merchant TE, Gollamudi S, Finlay JL
• High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer Group.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Dunkel IJ, Boyett JM, Yates A, Rosenblum M, Garvin JH, Bostrom BC, Goldman S, Sender LS, Gardner SL, Li H, Allen JC, Finlay JL
• Enolate Additions to a Chiral 3-Hydroxypropionate 2,3-Dication Equivalent. Enantioselective Synthesis of beta,delta-Dihydroxy Esters.
  The Journal of organic chemistry 1997 Zhen W, Chu KH, Rosenblum M
• Primary amyloidoma of the brain: CT and MR presentation.
  AJNR. American journal of neuroradiology 1995 Lee J, Krol G, Rosenblum M
• Development of a non-selecting, non-perturbing method to study human brain tumor cell invasion in murine brain.
  Journal of neuro-oncology 1994 DeArmond SJ, Stowring L, Amar A, Coopersmith P, Dougherty D, Spencer D, Mikkelsen T, Rosenblum M
• Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma.
  Blood 1994 Minasian LM, Szatrowski TP, Rosenblum M, Steffens T, Morrison ME, Chapman PB, Williams L, Nathan CF, Houghton AN
• Microtubule aggregates in a clival chordoma.
  Archives of pathology & laboratory medicine 1993 Jeffrey PB, Davis RL, Biava C, Rosenblum M
• Neoplastic meningitis as the presentation of occult primitive neuroectodermal tumors.
  Journal of child neurology 1993 Jennings MT, Slatkin N, D'Angelo M, Ketonen L, Johnson MD, Rosenblum M, Creasy J, Tulipan N, Walker R
• Developmental regulation of annexin II (Lipocortin 2) in human brain and expression in high grade glioma.
  Cancer research 1992 Reeves SA, Chavez-Kappel C, Davis R, Rosenblum M, Israel MA
• Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expressing the IL-2 receptor.
  Blood 1992 LeMaistre CF, Meneghetti C, Rosenblum M, Reuben J, Parker K, Shaw J, Deisseroth A, Woodworth T, Parkinson DR
• Low dose rate radiotherapy for transplantable gliosarcoma in the rat brain.
  Journal of neuro-oncology 1990 Kim JH, Alfieri AA, Rosenblum M, Bravo S, Kim SH
• AIDS-related vacuolar myelopathy is not associated with coinfection by human T-lymphotropic virus type I.
  Annals of neurology 1989 Brew BJ, Hardy W, Zuckerman E, Chien N, Paul M, Rosenblum M, Gadler H, Vahlne A, Gold J, Armstrong DA
• Dissociation of AIDS-related vacuolar myelopathy and productive HIV-1 infection of the spinal cord.
  Neurology 1989 Rosenblum M, Scheck AC, Cronin K, Brew BJ, Khan A, Paul M, Price RW
• Clinical and laboratory changes induced by alpha interferon in chronic lymphocytic leukemia--a pilot study.
  American journal of hematology 1987 Talpaz M, Rosenblum M, Kurzrock R, Reuben J, Kantarjian H, Gutterman J
• Initial clinical studies with copovithane.
  Journal of biological response modifiers 1986 Hortobagyi GN, Hersh EM, Papadopoulos NE, Frye D, Rios A, Reuben JM, Plager C, Rosenblum M, Quesada J
• Depression of murine natural killer cell cytotoxicity by isobutyl nitrite.
  Cancer immunology, immunotherapy : CII 1984 Lotzová E, Savary CA, Hersh EM, Khan AA, Rosenblum M