Michael Prados, MD
Professor
Neurological Surgery
School of Medicine

He became the Project Leader of the North America Brain Tumor Consortium (NABTC), an NCI-CTEP supported multi-institutional early phase clinical trials consortium, and led that group for 15 years. When the NABTC merged with the NABTT (and became the Adult Brain Tumor Consortium) he was named co-Project Leader until stepping down in early 2014. In 2009, he was awarded the Project Leadership of what is called the Ivy Foundation Early Phase Clinical Trials Consortium, a group of now 7 major academic centers who conduct clinical and translation research in adults with brain cancer. The Consortium is now led by Nicholas Butowski, MD from UCSF.

He was the Institutional site Principal Investigator for the Pediatric Brain Tumor Consortium (PBTC) for over 10 years, ending that role in 2012. Shortly thereafter he formed the Pacific Pediatric Neuro-Oncology Consortium (PNOC), a multi-institutional consortium of now 15 major academic centers across the United States, conducing early phase, precision-focused, clinical trials in young children and adolescents. Dr. Prados retired from UCSF in October 2015, and the PNOC is now led by Sabine Mueller, MD, PhD.

UCSF requested that Dr. Prados return on a part-time basis in January 2016 as Professor Emeritus, to devote his efforts towards pediatric Neuro-Oncology clinical and translational research. Towards that end, he is the co-Project Leader of a pediatric brain tumor SPORE project at UCSF, and is co-Project Leader of the PNOC. His academic appointments are within Neurosurgery, retaining the Charles B. Wilson endowed chair, and the Department of Pediatrics.

His major interests are early phase clinical trials research, and the translational studies that precede and inform those trials in both adults and children. He has published over 300 articles since 1985, has been NIH/NCI funded continuously since 1994 and is part of the Editorial board of Neuro-Oncology, Journal of Neuro-Oncology and Journal of Clinical Oncology, and a member of the NCI/CTEP Brain Malignancies Steering Committee. In 2014 he was awarded the Victor Levin Award for lifetime clinical research excellence from the Society of Neuro-Oncology.

• PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.
  Neuro-oncology 2023 Mueller S, Kline C, Stoller S, Lundy S, Christopher L, Reddy AT, Banerjee A, Cooney TM, Raber S, Hoffman C, Luks T, Wembacher-Schroeder E, Lummel N, Zhang Y, Bonner ER, Nazarian J, Molinaro AM, Prados…
• Current Strategies for Management of Medulloblastoma.
  Diagnostics (Basel, Switzerland) 2023 Prados MD
• Applying collaborative brain power to pull us out of the dark ages of pediatric neuro-oncology.
  Neoplasia (New York, N.Y.) 2023 Koschmann C, Prados M
• Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks.
  Frontiers in oncology 2023 Jones C, Straathof K, Fouladi M, Hargrave D, Prados M, Resnick A, Doz F, Jones DTW, Mueller S
• mRNA aggregates harness danger response for potent cancer immunotherapy.
  medRxiv : the preprint server for health sciences 2023 Mendez-Gomez HR, DeVries A, Castillo P, Stover BD, Qdaisat S, Von Roemeling C, Ogando-Rivas E, Weidert F, McGuiness J, Zhang D, Chung MC, Li D, Zhang C, Marconi C, Campaneria Y, Chardon-Robles J, …
• Automated tumor segmentation and brain tissue extraction from multiparametric MRI of pediatric brain tumors: A multi-institutional study.
  Neuro-oncology advances 2023 Fathi Kazerooni A, Arif S, Madhogarhia R, Khalili N, Haldar D, Bagheri S, Familiar AM, Anderson H, Haldar S, Tu W, Chul Kim M, Viswanathan K, Muller S, Prados M, Kline C, Vidal L, Aboian M, Storm PB, …
• Automated Tumor Segmentation and Brain Tissue Extraction from Multiparametric MRI of Pediatric Brain Tumors: A Multi-Institutional Study.
  medRxiv : the preprint server for health sciences 2023 Kazerooni AF, Arif S, Madhogarhia R, Khalili N, Haldar D, Bagheri S, Familiar AM, Anderson H, Haldar S, Tu W, Kim MC, Viswanathan K, Muller S, Prados M, Kline C, Vidal L, Aboian M, Storm PB, Resnick …
• Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer.
  Science translational medicine 2023 Budhraja KK, McDonald BR, Stephens MD, Contente-Cuomo T, Markus H, Farooq M, Favaro PF, Connor S, Byron SA, Egan JB, Ernst B, McDaniel TK, Sekulic A, Tran NL, Prados MD, Borad MJ, Berens ME, Pockaj BA…
• ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.
  Journal of neuro-oncology 2022 Sloan AE, Nock CJ, Ye X, Buerki R, Chang S, Lesser G, Norden A, Cloughesy T, Olson J, Kerstetter-Fogle A, Rich J, Fisher J, Desideri S, Takebe N, Timmer W, Grossman S, Prados M
• The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.
  Neoplasia (New York, N.Y.) 2022 Lilly JV, Rokita JL, Mason JL, Patton T, Stefankiewiz S, Higgins D, Trooskin G, Larouci CA, Arya K, Appert E, Heath AP, Zhu Y, Brown MA, Zhang B, Farrow BK, Robins S, Morgan AM, Nguyen TQ, Frenkel E, …
• Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Kline C, Jain P, Kilburn L, Bonner ER, Gupta N, Crawford JR, Banerjee A, Packer RJ, Villanueva-Meyer J, Luks T, Zhang Y, Kambhampati M, Zhang J, Yadavilli S, Zhang B, Gaonkar KS, Rokita JL, Kraya A, …
• Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
  The Journal of clinical investigation 2022 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, …
• A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma.
  Journal of neuro-oncology 2021 Bush NAO, Young JS, Zhang Y, Dalle Ore CL, Molinaro AM, Taylor J, Clarke J, Prados M, Braunstein SE, Raleigh DR, Chang SM, Berger MS, Butowski NA
• BRCA1 Protein Expression Predicts Survival in Glioblastoma Patients from an NRG Oncology RTOG Cohort.
  Oncology 2021 Vassilakopoulou M, Won M, Curran WJ, Souhami L, Prados MD, Langer CJ, Rimm DL, Hanna JA, Neumeister VM, Melian E, Diaz AZ, Atkins JN, Komarnicky LT, Schultz CJ, Howard SP, Zhang P, Dicker AP, Knisely …
• Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
  The Journal of clinical investigation 2020 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, …
• Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02.
  Neuro-oncology advances 2020 Chen H, Kuhn J, Lamborn KR, Abrey LE, DeAngelis LM, Lieberman F, Robins HI, Chang SM, Yung WKA, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Wen PY, Gilbert…
• Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
  The Lancet. Oncology 2020 Erker C, Tamrazi B, Poussaint TY, Mueller S, Mata-Mbemba D, Franceschi E, Brandes AA, Rao A, Haworth KB, Wen PY, Goldman S, Vezina G, MacDonald TJ, Dunkel IJ, Morgan PS, Jaspan T, Prados MD, Warren KE
• Population Pharmacokinetics of Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E-Mutant Astrocytomas.
  Journal of clinical pharmacology 2020 Wang H, Long-Boyle J, Winger BA, Nicolaides T, Mueller S, Prados M, Ivaturi V
• Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).
  Oncotarget 2020 Nicolaides T, Nazemi KJ, Crawford J, Kilburn L, Minturn J, Gajjar A, Gauvain K, Leary S, Dhall G, Aboian M, Robinson G, Long-Boyle J, Wang H, Molinaro AM, Mueller S, Prados M
• Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.
  JAMA oncology 2020 Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C…
• Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.
  PloS one 2019 Berens ME, Sood A, Barnholtz-Sloan JS, Graf JF, Cho S, Kim S, Kiefer J, Byron SA, Halperin RF, Nasser S, Adkins J, Cuyugan L, Devine K, Ostrom Q, Couce M, Wolansky L, McDonough E, Schyberg S, Dinn S, …
• Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma.
  Neuro-oncology practice 2019 Cooney T, Yeo KK, Kline C, Prados M, Haas-Kogan D, Chi S, Mueller S
• Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM.
  Molecular cancer therapeutics 2019 McKinney A, Lindberg OR, Engler JR, Chen KY, Kumar A, Gong H, Lu KV, Simonds EF, Cloughesy TF, Liau LM, Prados M, Bollen AW, Berger MS, Shieh JTC, James CD, Nicolaides TP, Yong WH, Lai A, Hegi ME, …
• A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
  International journal of cancer 2019 Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips …
• Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2019 Wen PY, Touat M, Alexander BM, Mellinghoff IK, Ramkissoon S, McCluskey CS, Pelton K, Haidar S, Basu SS, Gaffey SC, Brown LE, Martinez-Ledesma JE, Wu S, Kim J, Wei W, Park MA, Huse JT, Kuhn JG, Rinne …
• Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Panditharatna E, Kilburn LB, Aboian MS, Kambhampati M, Gordish-Dressman H, Magge SN, Gupta N, Myseros JS, Hwang EI, Kline C, Crawford JR, Warren KE, Cha S, Liang WS, Berens ME, Packer RJ, Resnick AC, …
• Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
  Neuro-oncology 2018 Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z,…
• Attitudes toward fertility and fertility preservation in women with glioma.
  Neuro-oncology practice 2018 Stiner RK, Clarke JL, Sinha N, Chan J, Letourneau JM, Niemasik EE, Rabbitt JE, Chang SM, Butowski NA, Prados MD, Rosen MP
• Using genomics to guide treatment for glioblastoma.
  Pharmacogenomics 2018 Young JS, Prados MD, Butowski N
• Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma.
  Neuro-oncology 2018 Ellingson BM, Aftab DT, Schwab GM, Hessel C, Harris RJ, Woodworth DC, Leu K, Chakhoyan A, Raymond C, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, …
• Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma.
  Journal of neuro-oncology 2018 Taylor JW, Parikh M, Phillips JJ, James CD, Molinaro AM, Butowski NA, Clarke JL, Oberheim-Bush NA, Chang SM, Berger MS, Prados M
• Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.
  Neuro-oncology 2018 Ellingson BM, Abrey LE, Nelson SJ, Kaufmann TJ, Garcia J, Chinot O, Saran F, Nishikawa R, Henriksson R, Mason WP, Wick W, Butowski N, Ligon KL, Gerstner ER, Colman H, de Groot J, Chang S, Mellinghoff …
• Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02.
  Neuro-oncology 2018 Galanis E, Anderson SK, Miller CR, Sarkaria JN, Jaeckle K, Buckner JC, Ligon KL, Ballman KV, Moore DF, Nebozhyn M, Loboda A, Schiff D, Ahluwalia MS, Lee EQ, Gerstner ER, Lesser GJ, Prados M, Grossman …
• Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy.
  Neuro-oncology 2018 Wen PY, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, Holland J, Ping J, Weitzman R, Cloughesy TF
• Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy.
  Neuro-oncology 2018 Cloughesy TF, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, Ping J, Holland J, Weitzman R, Wen PY
• Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology committee.
  Neuro-oncology 2018 Warren KE, Vezina G, Poussaint TY, Warmuth-Metz M, Chamberlain MC, Packer RJ, Brandes AA, Reiss M, Goldman S, Fisher MJ, Pollack IF, Prados MD, Wen PY, Chang SM, Dufour C, Zurakowski D, Kortmann RD, …
• Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, …
• Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02.
  Journal of neuro-oncology 2017 Nghiemphu PL, Ebiana VA, Wen P, Gilbert M, Abrey LE, Lieberman F, DeAngelis LM, Robins HI, Yung WKA, Chang S, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados M, Kuhn J, …
• A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
  Neuro-oncology 2017 Banerjee A, Jakacki RI, Onar-Thomas A, Wu S, Nicolaides T, Young Poussaint T, Fangusaro J, Phillips J, Perry A, Turner D, Prados M, Packer RJ, Qaddoumi I, Gururangan S, Pollack IF, Goldman S, Doyle LA…
• Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
  Cancer 2017 Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D
• Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.
  Journal of neuro-oncology 2017 Ulasov IV, Foster H, Butters M, Yoon JG, Ozawa T, Nicolaides T, Figueroa X, Hothi P, Prados M, Butters J, Cobbs C
• A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma.
  Cancer chemotherapy and pharmacology 2017 Clarke JL, Molinaro AM, Cabrera JR, DeSilva AA, Rabbitt JE, Prey J, Drummond DC, Kim J, Noble C, Fitzgerald JB, Chang SM, Butowski NA, Taylor JW, Park JW, Prados MD
• Clinical trial endpoints for patients with gliomas.
  Neuro-oncology practice 2017 Taylor JW, Molinaro AM, Butowski N, Prados M
• Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
  Neuro-oncology 2017 Wahl M, Phillips JJ, Molinaro AM, Lin Y, Perry A, Haas-Kogan DA, Costello JF, Dayal M, Butowski N, Clarke JL, Prados M, Nelson S, Berger MS, Chang SM
• Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas.
  Journal of neuro-oncology 2017 Nayak L, de Groot J, Wefel JS, Cloughesy TF, Lieberman F, Chang SM, Omuro A, Drappatz J, Batchelor TT, DeAngelis LM, Gilbert MR, Aldape KD, Yung AW, Fisher J, Ye X, Chen A, Grossman S, Prados M, Wen …
• Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas.
  Oncotarget 2017 Yao TW, Zhang J, Prados M, Weiss WA, James CD, Nicolaides T
• Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas.
  Journal of neuro-oncology 2016 Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan QW, Prados M, James CD, Weiss WA, Nicolaides T
• Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
  Journal of neuro-oncology 2016 Nelson SJ, Li Y, Lupo JM, Olson M, Crane JC, Molinaro A, Roy R, Clarke J, Butowski N, Prados M, Cha S, Chang SM
• Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
  Neuro-oncology 2016 Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD
• Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016 Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, Lipp ES, Dunham C, Hukin J, …
• Biopsy for diffuse intrinsic pontine glioma: a reappraisal.
  Journal of neurosurgery. Pediatrics 2016 Kieran MW, Goumnerova LC, Prados M, Gupta N
• Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
  Journal of neuro-oncology 2016 Dasgupta T, Olow AK, Yang X, Hashizume R, Nicolaides TP, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, James CD, Mueller S, Haas-Kogan DA
• Clinical outcome and prognostic factors for central neurocytoma: twenty year institutional experience.
  Journal of neuro-oncology 2016 Imber BS, Braunstein SE, Wu FY, Nabavizadeh N, Boehling N, Weinberg VK, Tihan T, Barnes M, Mueller S, Butowski NA, Clarke JL, Chang SM, McDermott MM, Prados MD, Berger MS, Haas-Kogan DA
• Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
  Oncotarget 2015 Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS, Hansen HM, Elhauge E, Ojha J, Francis SS, Madsen NR, Bracci PM, Pico AR, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD, Jenkins RB, …
• Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials.
  Translational oncology 2015 Wen Q, Jalilian L, Lupo JM, Li Y, Roy R, Molinaro AM, Chang SM, Prados M, Butowski N, Clarke J, Nelson SJ
• Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study.
  Neuro-oncology 2015 Butowski N, Colman H, De Groot JF, Omuro AM, Nayak L, Wen PY, Cloughesy TF, Marimuthu A, Haidar S, Perry A, Huse J, Phillips J, West BL, Nolop KB, Hsu HH, Ligon KL, Molinaro AM, Prados M
• Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.
  Journal of neuro-oncology 2015 Dasgupta T, Olow AK, Yang X, Hashizume R, Nicolaides TP, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, James CD, Mueller S, Haas-Kogan DA
• EGFR blockade prevents glioma escape from BRAFV600E targeted therapy.
  Oncotarget 2015 Yao TW, Zhang J, Prados M, Weiss WA, James CD, Nicolaides T
• Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Gounder MM, Nayak L, Sahebjam S, Muzikansky A, Sanchez AJ, Desideri S, Ye X, Ivy SP, Nabors LB, Prados M, Grossman S, DeAngelis LM, Wen PY
• Impact of Timing of Concurrent Chemoradiation for Newly Diagnosed Glioblastoma: A Critical Review of Current Evidence.
  Neurosurgery 2015 Han SJ, Englot DJ, Birk H, Molinaro AM, Chang SM, Clarke JL, Prados MD, Taylor JW, Berger MS, Butowski NA
• The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma.
  Neurosurgery 2015 Han SJ, Rutledge WC, Molinaro AM, Chang SM, Clarke JL, Prados MD, Taylor JW, Berger MS, Butowski NA
• Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Robinson GW, Orr BA, Wu G, Gururangan S, Lin T, Qaddoumi I, Packer RJ, Goldman S, Prados MD, Desjardins A, Chintagumpala M, Takebe N, Kaste SC, Rusch M, Allen SJ, Onar-Thomas A, Stewart CF, Fouladi M,…
• Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
  The New England journal of medicine 2015 Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy …
• Toward precision medicine in glioblastoma: the promise and the challenges.
  Neuro-oncology 2015 Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, …
• Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
  Journal of neuro-oncology 2014 Wen Q, Jalilian L, Lupo JM, Molinaro AM, Chang SM, Clarke J, Prados M, Nelson SJ
• Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD).
  Neuro-oncology 2014 Wen PY, Cloughesy TF, Ellingson BM, Reardon DA, Fine HA, Abrey L, Ballman K, Bendszuz M, Buckner J, Chang SM, Prados MD, Pope WB, Gregory Sorensen A, van den Bent M, Yung WK
• Familial gliomas: cases in two pairs of brothers.
  Journal of neuro-oncology 2014 Osorio JA, Hervey-Jumper SL, Walsh KM, Clarke JL, Butowski NA, Prados MD, Berger MS
• Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group.
  Neuro-oncology 2014 Alexander BM, Galanis E, Yung WK, Ballman KV, Boyett JM, Cloughesy TF, Degroot JF, Huse JT, Mann B, Mason W, Mellinghoff IK, Mikkelsen T, Mischel PS, O'Neill BP, Prados MD, Sarkaria JN, Tawab-Amiri A,…
• Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients.
  Neuro-oncology 2014 Vera-Bolanos E, Aldape K, Yuan Y, Wu J, Wani K, Necesito-Reyes MJ, Colman H, Dhall G, Lieberman FS, Metellus P, Mikkelsen T, Omuro A, Partap S, Prados M, Robins HI, Soffietti R, Wu J, Gilbert MR, …
• A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
  Neuro-oncology 2014 Clarke JL, Molinaro AM, Phillips JJ, Butowski NA, Chang SM, Perry A, Costello JF, DeSilva AA, Rabbitt JE, Prados MD
• Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
  Nature genetics 2014 Walsh KM, Codd V, Smirnov IV, Rice T, Decker PA, Hansen HM, Kollmeyer T, Kosel ML, Molinaro AM, McCoy LS, Bracci PM, Cabriga BS, Pekmezci M, Zheng S, Wiemels JL, Pico AR, Tihan T, Berger MS, Chang SM,…
• Plexiform neurofibromas, trial design, and the definitions of "progression" and "treatment failure".
  Neuro-oncology 2014 Prados MD
• Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
  Nature genetics 2014 Fontebasso AM, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset PO, Bechet D, Faury D, De Jay N, Ramkissoon LA, Corcoran A, Jones DT, Sturm D, Johann P, Tomita T, Goldman S, Nagib …
• "We will know it when we see it;" bevacizumab and glioblastoma.
  Neuro-oncology 2014 Prados MD
• Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma.
  Neuro-oncology 2014 Han SJ, Rolston JD, Molinaro AM, Clarke JL, Prados MD, Chang SM, Berger MS, DeSilva A, Butowski NA
• Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02.
  Neuro-oncology 2014 Wen PY, Chang SM, Lamborn KR, Kuhn JG, Norden AD, Cloughesy TF, Robins HI, Lieberman FS, Gilbert MR, Mehta MP, Drappatz J, Groves MD, Santagata S, Ligon AH, Yung WK, Wright JJ, Dancey J, Aldape KD, …
• Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial.
  Neuro-oncology 2013 Bloch O, Crane CA, Fuks Y, Kaur R, Aghi MK, Berger MS, Butowski NA, Chang SM, Clarke JL, McDermott MW, Prados MD, Sloan AE, Bruce JN, Parsa AT
• Targeting Wee1 for the treatment of pediatric high-grade gliomas.
  Neuro-oncology 2013 Mueller S, Hashizume R, Yang X, Kolkowitz I, Olow AK, Phillips J, Smirnov I, Tom MW, Prados MD, James CD, Berger MS, Gupta N, Haas-Kogan DA
• The somatic genomic landscape of glioblastoma.
  Cell 2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, Barnholtz-Sloan J, Zou L, …
• Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.
  Neuro-oncology 2013 Walsh KM, Rice T, Decker PA, Kosel ML, Kollmeyer T, Hansen HM, Zheng S, McCoy LS, Bracci PM, Anderson E, Hsuang G, Wiemels JL, Pico AR, Smirnov I, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD,…
• Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.
  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Cage TA, Samagh SP, Mueller S, Nicolaides T, Haas-Kogan D, Prados M, Banerjee A, Auguste KI, Gupta N
• Gliosarcoma arising from an oligodendroglioma (oligosarcoma).
  Clinical neuropathology 2013 Hiniker A, Hagenkord JM, Powers MP, Aghi MK, Prados MD, Perry A
• Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group.
  Pediatric blood & cancer 2013 Warren KE, Poussaint TY, Vezina G, Hargrave D, Packer RJ, Goldman S, Wen PY, Pollack IF, Zurakowski D, Kun LE, Prados MD, Rutkowski S, Kieran MW
• Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system.
  Brain pathology (Zurich, Switzerland) 2013 Raghunathan A, Wani K, Armstrong TS, Vera-Bolanos E, Fouladi M, Gilbertson R, Gajjar A, Goldman S, Lehman NL, Metellus P, Mikkelsen T, Necesito-Reyes MJ, Omuro A, Packer RJ, Partap S, Pollack IF, …
• Subependymal spread of recurrent glioblastoma detected with the intraoperative use of 5-aminolevulinic acid: case report.
  Journal of neurosurgery 2013 Cage TA, Pekmezci M, Prados M, Berger MS
• Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.
  Neuro-oncology 2013 Rice T, Zheng S, Decker PA, Walsh KM, Bracci P, Xiao Y, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron A, Fink S, Kollmeyer T,…
• Cytokines associated with toxicity in the treatment of recurrent glioblastoma with aflibercept.
  Targeted oncology 2013 Shonka N, Piao Y, Gilbert M, Yung A, Chang S, DeAngelis LM, Lassman AB, Liu J, Cloughesy T, Robins HI, Lloyd R, Chen A, Prados M, Wen PY, Heymach J, de Groot J
• Improvement of therapeutic compliance in haemodialysis patients with poor phosphorus control and adherence to treatment with binders: COMQUELFOS study.
  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 2013 Dolores Arenas M, Pérez-García R, Bennouna M, Blanco A, Mauricio O, Prados MD, Lerma JL, Luisa Muñiz M, Belén Martín M, Estudio COMQUELFOS
• Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts.
  Neuro-oncology 2012 Chen PY, Ozawa T, Drummond DC, Kalra A, Fitzgerald JB, Kirpotin DB, Wei KC, Butowski N, Prados MD, Berger MS, Forsayeth JR, Bankiewicz K, James CD
• Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02.
  Neuro-oncology 2012 Lee EQ, Kuhn J, Lamborn KR, Abrey L, DeAngelis LM, Lieberman F, Robins HI, Chang SM, Yung WK, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Gilbert MR, Wen …
• Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
  Journal of neuro-oncology 2012 Hashizume R, Smirnov I, Liu S, Phillips JJ, Hyer J, McKnight TR, Wendland M, Prados M, Banerjee A, Nicolaides T, Mueller S, James CD, Gupta N
• A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.
  Nature genetics 2012 Jenkins RB, Xiao Y, Sicotte H, Decker PA, Kollmeyer TM, Hansen HM, Kosel ML, Zheng S, Walsh KM, Rice T, Bracci P, McCoy LS, Smirnov I, Patoka JS, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, …
• Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Lee EQ, Puduvalli VK, Reid JM, Kuhn JG, Lamborn KR, Cloughesy TF, Chang SM, Drappatz J, Yung WK, Gilbert MR, Robins HI, Lieberman FS, Lassman AB, McGovern RM, Xu J, Desideri S, Ye X, Ames MM, Espinoza…
• Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Crane CA, Han SJ, Ahn B, Oehlke J, Kivett V, Fedoroff A, Butowski N, Chang SM, Clarke J, Berger MS, McDermott MW, Prados MD, Parsa AT
• Multicenter phase II study of rituximab and temozolomide in recurrent primary central nervous system lymphoma.
  Leukemia & lymphoma 2012 Nayak L, Abrey LE, Drappatz J, Gilbert MR, Reardon DA, Wen PY, Prados M, Deangelis LM, Omuro A, North American Brain Tumor Consortium
• PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
  Neuro-oncology 2012 Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA
• Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Ater JL, Zhou T, Holmes E, Mazewski CM, Booth TN, Freyer DR, Lazarus KH, Packer RJ, Prados M, Sposto R, Vezina G, Wisoff JH, Pollack IF
• SSBP2 variants are associated with survival in glioblastoma patients.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Xiao Y, Decker PA, Rice T, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Wiemels JL, Tihan T, Prados MD, Chang SM, Berger MS, Kosel ML, Fridley BL, Lachance DH, O'Neill BP, Buckner JC, Thompson RC, …
• Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors.
  Cancer discovery 2012 Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, Nghiemphu PL, Kubek S, Oldrini B, Chheda MG, Yannuzzi N, Tao H, Zhu S, Iwanami A, Kuga D, Dang J, Pedraza A, Brennan CW, Heguy A, Liau LM, Lieberman…
• Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study.
  Journal of neuro-oncology 2012 Pope WB, Qiao XJ, Kim HJ, Lai A, Nghiemphu P, Xue X, Ellingson BM, Schiff D, Aregawi D, Cha S, Puduvalli VK, Wu J, Yung WK, Young GS, Vredenburgh J, Barboriak D, Abrey LE, Mikkelsen T, Jain R, …
• Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients.
  Cancer chemotherapy and pharmacology 2012 Reardon DA, Conrad CA, Cloughesy T, Prados MD, Friedman HS, Aldape KD, Mischel P, Xia J, DiLea C, Huang J, Mietlowski W, Dugan M, Chen W, Yung WK
• A prognostic gene expression signature in infratentorial ependymoma.
  Acta neuropathologica 2012 Wani K, Armstrong TS, Vera-Bolanos E, Raghunathan A, Ellison D, Gilbertson R, Vaillant B, Goldman S, Packer RJ, Fouladi M, Pollack I, Mikkelsen T, Prados M, Omuro A, Soffietti R, Ledoux A, Wilson C, …
• Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment.
  Neurosurgery 2012 Clark AJ, Lamborn KR, Butowski NA, Chang SM, Prados MD, Clarke JL, McDermott MW, Parsa AT, Berger MS, Aghi MK
• An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing.
  Journal of neuro-oncology 2012 Aoki Y, Hashizume R, Ozawa T, Banerjee A, Prados M, James CD, Gupta N
• Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association with the proneural subtype.
  Journal of neuropathology and experimental neurology 2012 Goldhoff P, Clarke J, Smirnov I, Berger MS, Prados MD, James CD, Perry A, Phillips JJ
• Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang …
• Conditional probability of survival in patients with newly diagnosed glioblastoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Polley MY, Lamborn KR, Chang SM, Butowski N, Clarke JL, Prados M
• Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts.
  Neuro-oncology 2011 Serwer LP, Noble CO, Michaud K, Drummond DC, Kirpotin DB, Ozawa T, Prados MD, Park JW, James CD
• An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.
  Cancer discovery 2011 Guo D, Reinitz F, Youssef M, Hong C, Nathanson D, Akhavan D, Kuga D, Amzajerdi AN, Soto H, Zhu S, Babic I, Tanaka K, Dang J, Iwanami A, Gini B, Dejesus J, Lisiero DD, Huang TT, Prins RM, Wen PY, …
• Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
  Neuro-oncology 2011 Butowski N, Chang SM, Lamborn KR, Polley MY, Pieper R, Costello JF, Vandenberg S, Parvataneni R, Nicole A, Sneed PK, Clarke J, Hsieh E, Costa BM, Reis RM, Hristova-Kazmierski M, Nicol SJ, Thornton DE,…
• Pediatric intracranial ependymoma: the roles of surgery, radiation and chemotherapy.
  Journal of neuro-oncology 2011 Pejavar S, Polley MY, Rosenberg-Wohl S, Chennupati S, Prados MD, Berger MS, Banerjee A, Gupta N, Haas-Kogan D
• Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?
  Neuro-oncology 2011 Clarke JL, Ennis MM, Yung WK, Chang SM, Wen PY, Cloughesy TF, Deangelis LM, Robins HI, Lieberman FS, Fine HA, Abrey L, Gilbert MR, Mehta M, Kuhn JG, Aldape KD, Lamborn KR, Prados MD, North American …
• It is time to include patients with brain tumors in phase I trials in oncology.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Wen PY, Schiff D, Cloughesy TF, Reardon DA, Batchelor TT, Chabner BA, Flaherty K, de Groot JF, Gilbert MR, Galanis E, Chang SM, Schwartz GK, Peereboom D, Mehta MP, Yung WK, Grossman SA, Prados MD, …
• Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery.
  Journal of neuro-oncology 2011 Gilbert MR, Kuhn J, Lamborn KR, Lieberman F, Wen PY, Mehta M, Cloughesy T, Lassman AB, Deangelis LM, Chang S, Prados M
• Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 de Groot JF, Piao Y, Tran H, Gilbert M, Wu HK, Liu J, Bekele BN, Cloughesy T, Mehta M, Robins HI, Lassman A, DeAngelis L, Camphausen K, Chen A, Yung WK, Prados M, Wen PY, Heymach JV
• Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 de Groot JF, Lamborn KR, Chang SM, Gilbert MR, Cloughesy TF, Aldape K, Yao J, Jackson EF, Lieberman F, Robins HI, Mehta MP, Lassman AB, Deangelis LM, Yung WK, Chen A, Prados MD, Wen PY
• Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab.
  Neuro-oncology 2011 Wefel JS, Cloughesy T, Zazzali JL, Zheng M, Prados M, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Das A, Friedman HS
• A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03.
  Neuro-oncology 2011 Iwamoto FM, Lamborn KR, Kuhn JG, Wen PY, Yung WK, Gilbert MR, Chang SM, Lieberman FS, Prados MD, Fine HA
• DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.
  Neuro-oncology 2011 Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, Haas-Kogan DA, McBride S, Marsit CJ, Christensen BC, Nelson HH, Stokoe D, Wiemels JL, Chang SM, Prados MD, Tihan T, Vandenberg SR, …
• Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas.
  Neuro-oncology 2011 Haas-Kogan DA, Banerjee A, Poussaint TY, Kocak M, Prados MD, Geyer JR, Fouladi M, Broniscer A, Minturn JE, Pollack IF, Packer RJ, Boyett JM, Kun LE
• The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA
• Identifying the needs of brain tumor patients and their caregivers.
  Journal of neuro-oncology 2011 Parvataneni R, Polley MY, Freeman T, Lamborn K, Prados M, Butowski N, Liu R, Clarke J, Page M, Rabbitt J, Fedoroff A, Clow E, Hsieh E, Kivett V, Deboer R, Chang S
• Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
  Neuro-oncology 2011 Prasad G, Sottero T, Yang X, Mueller S, James CD, Weiss WA, Polley MY, Ozawa T, Berger MS, Aftab DT, Prados MD, Haas-Kogan DA
• Impact of bevacizumab chemotherapy on craniotomy wound healing.
  Journal of neurosurgery 2010 Clark AJ, Butowski NA, Chang SM, Prados MD, Clarke J, Polley MY, Sughrue ME, McDermott MW, Parsa AT, Berger MS, Aghi MK
• Corticosteroid use in patients with glioblastoma at first or second relapse treated with bevacizumab in the BRAIN study.
  The oncologist 2010 Vredenburgh JJ, Cloughesy T, Samant M, Prados M, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Das A, Friedman HS
• Response as a predictor of survival in patients with recurrent glioblastoma treated with bevacizumab.
  Neuro-oncology 2010 Prados M, Cloughesy T, Samant M, Fang L, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Das A, Friedman HS
• A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
  International journal of radiation oncology, biology, physics 2010 Nghiemphu PL, Wen PY, Lamborn KR, Drappatz J, Robins HI, Fink K, Malkin MG, Lieberman FS, DeAngelis LM, Torres-Trejo A, Chang SM, Abrey L, Fine HA, Demopoulos A, Lassman AB, Kesari S, Mehta MP, Prados…
• Inherited variation in immune genes and pathways and glioblastoma risk.
  Carcinogenesis 2010 Schwartzbaum JA, Xiao Y, Liu Y, Tsavachidis S, Berger MS, Bondy ML, Chang JS, Chang SM, Decker PA, Ding B, Hepworth SJ, Houlston RS, Hosking FJ, Jenkins RB, Kosel ML, McCoy LS, McKinney PA, Muir K, …
• Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study.
  Neuro-oncology 2010 Yung WK, Vredenburgh JJ, Cloughesy TF, Nghiemphu P, Klencke B, Gilbert MR, Reardon DA, Prados MD
• Brain tumors: from childhood through adolescence into adulthood.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Kieran MW, Walker D, Frappaz D, Prados M
• A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
  Cancer cell 2010 Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, …
• Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.
  Cancer research 2010 Michaud K, Solomon DA, Oermann E, Kim JS, Zhong WZ, Prados MD, Ozawa T, James CD, Waldman T
• Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.
  Journal of neuro-oncology 2010 Mishra KK, Squire S, Lamborn K, Banerjee A, Gupta N, Wara WM, Prados MD, Berger MS, Haas-Kogan DA
• Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02).
  Neuro-oncology 2010 Iwamoto FM, Lamborn KR, Robins HI, Mehta MP, Chang SM, Butowski NA, Deangelis LM, Abrey LE, Zhang WT, Prados MD, Fine HA
• Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients.
  Cancer 2010 Han SJ, Yang I, Ahn BJ, Otero JJ, Tihan T, McDermott MW, Berger MS, Prados MD, Parsa AT
• Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
  Neuro-oncology 2010 Butowski N, Chang SM, Lamborn KR, Polley MY, Parvataneni R, Hristova-Kazmierski M, Musib L, Nicol SJ, Thornton DE, Prados MD
• Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.
  Neuro-oncology 2010 Kunwar S, Chang S, Westphal M, Vogelbaum M, Sampson J, Barnett G, Shaffrey M, Ram Z, Piepmeier J, Prados M, Croteau D, Pedain C, Leland P, Husain SR, Joshi BH, Puri RK, PRECISE Study Group
• Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
  Neuro-oncology 2010 Hashizume R, Gupta N, Berger MS, Banerjee A, Prados MD, Ayers-Ringler J, James CD, VandenBerg SR
• Joint NCCTG and NABTC prognostic factors analysis for high-grade recurrent glioma.
  Neuro-oncology 2009 Wu W, Lamborn KR, Buckner JC, Novotny PJ, Chang SM, O'Fallon JR, Jaeckle KA, Prados MD
• Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
  Neuro-oncology 2009 Polley MY, Lamborn KR, Chang SM, Butowski N, Clarke JL, Prados M
• EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.
  Science signaling 2009 Guo D, Prins RM, Dang J, Kuga D, Iwanami A, Soto H, Lin KY, Huang TT, Akhavan D, Hock MB, Zhu S, Kofman AA, Bensinger SJ, Yong WH, Vinters HV, Horvath S, Watson AD, Kuhn JG, Robins HI, Mehta MP, Wen …
• A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas.
  Neuro-oncology 2009 Raizer JJ, Abrey LE, Lassman AB, Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Aldape KD, Wen PY, Fine HA, Mehta M, Deangelis LM, Lieberman F, Cloughesy TF, Robins HI, Dancey J, Prados MD, North…
• A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy.
  Neuro-oncology 2009 Raizer JJ, Abrey LE, Lassman AB, Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Aldape KA, Wen PY, Fine HA, Mehta M, Deangelis LM, Lieberman F, Cloughesy TF, Robins HI, Dancey J, Prados MD, North…
• Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).
  Neuro-oncology 2009 Wen PY, Yung WK, Lamborn KR, Norden AD, Cloughesy TF, Abrey LE, Fine HA, Chang SM, Robins HI, Fink K, Deangelis LM, Mehta M, Di Tomaso E, Drappatz J, Kesari S, Ligon KL, Aldape K, Jain RK, Stiles CD, …
• High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system.
  Journal of neuro-oncology 2009 Nicolaides T, Tihan T, Horn B, Biegel J, Prados M, Banerjee A
• Quality of Life and Patterns of Use of Complementary and Alternative Medicines Among Glioma Patients.
  The journal of supportive oncology 2009 Mobed K, Liu R, Stewart S, Wrensch M, McCoy L, Rice T, Prados M, Chang S
• Recurrent asymptomatic demyelinating disease following 13-cis-retinoic acid exposure.
  BMJ case reports 2009 Okuda DT, Prados MD
• Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Friedman HS, Prados MD, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Huang J, Zheng M, Cloughesy T
• Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.
  Journal of neuro-oncology 2009 McBride SM, Perez DA, Polley MY, Vandenberg SR, Smith JS, Zheng S, Lamborn KR, Wiencke JK, Chang SM, Prados MD, Berger MS, Stokoe D, Haas-Kogan DA
• IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
  International journal of cancer 2009 Wiemels JL, Wilson D, Patil C, Patoka J, McCoy L, Rice T, Schwartzbaum J, Heimberger A, Sampson JH, Chang S, Prados M, Wiencke JK, Wrensch M
• Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity.
  Journal of neuro-oncology 2009 Han SJ, Yang I, Tihan T, Prados MD, Parsa AT
• A human brainstem glioma xenograft model enabled for bioluminescence imaging.
  Journal of neuro-oncology 2009 Hashizume R, Ozawa T, Dinca EB, Banerjee A, Prados MD, James CD, Gupta N
• Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
  Nature genetics 2009 Wrensch M, Jenkins RB, Chang JS, Yeh RF, Xiao Y, Decker PA, Ballman KV, Berger M, Buckner JC, Chang S, Giannini C, Halder C, Kollmeyer TM, Kosel ML, LaChance DH, McCoy L, O'Neill BP, Patoka J, Pico AR…
• Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma.
  Journal of neuro-oncology 2009 Norden AD, Raizer JJ, Abrey LE, Lamborn KR, Lassman AB, Chang SM, Yung WK, Gilbert MR, Fine HA, Mehta M, Deangelis LM, Cloughesy TF, Robins HI, Aldape K, Dancey J, Prados MD, Lieberman F, Wen PY
• Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis.
  Journal of neurosurgery. Spine 2009 Guppy KH, Akins PT, Moes GS, Prados MD
• Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma.
  Journal of neuro-oncology 2009 Chang SM, Nelson S, Vandenberg S, Cha S, Prados M, Butowski N, McDermott M, Parsa AT, Aghi M, Clarke J, Berger M
• A phase II study of preradiotherapy chemotherapy followed by hyperfractionated radiotherapy for newly diagnosed high-risk medulloblastoma/primitive neuroectodermal tumor: a report from the Children's Oncology Group (CCG 9931).
  International journal of radiation oncology, biology, physics 2009 Allen J, Donahue B, Mehta M, Miller DC, Rorke LB, Jakacki R, Robertson P, Sposto R, Holmes E, Vezina G, Muraszko K, Puccetti D, Prados M, Chan KW
• Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Prados MD, Chang SM, Butowski N, DeBoer R, Parvataneni R, Carliner H, Kabuubi P, Ayers-Ringler J, Rabbitt J, Page M, Fedoroff A, Sneed PK, Berger MS, McDermott MW, Parsa AT, Vandenberg S, James CD, …
• p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
  Cancer research 2008 Dinca EB, Lu KV, Sarkaria JN, Pieper RO, Prados MD, Haas-Kogan DA, Vandenberg SR, Berger MS, James CD
• Preoperative prognostic classification system for hemispheric low-grade gliomas in adults.
  Journal of neurosurgery 2008 Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, Barbaro NM, Parsa AT, Berger MS, McDermott MM
• A North American brain tumor consortium phase II study of poly-ICLC for adult patients with recurrent anaplastic gliomas.
  Journal of neuro-oncology 2008 Butowski N, Lamborn KR, Lee BL, Prados MD, Cloughesy T, DeAngelis LM, Abrey L, Fink K, Lieberman F, Mehta M, Ian Robins H, Junck L, Salazar AM, Chang SM
• A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05).
  Journal of neuro-oncology 2008 Butowski N, Chang SM, Junck L, DeAngelis LM, Abrey L, Fink K, Cloughesy T, Lamborn KR, Salazar AM, Prados MD
• In reference to lamborn et Al. (Neuro-oncology. 2008;10:162-170).
  Neuro-oncology 2008 Meyers CA, Lamborn KR, Prados MD
• Quality of life in low-grade glioma patients receiving temozolomide.
  Neuro-oncology 2008 Liu R, Solheim K, Polley MY, Lamborn KR, Page M, Fedoroff A, Rabbitt J, Butowski N, Prados M, Chang SM
• Neurooncology clinical trial design for targeted therapies: lessons learned from the North American Brain Tumor Consortium.
  Neuro-oncology 2008 Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Wen PY, Fine HA, Mehta MP, DeAngelis LM, Lieberman FS, Cloughesy TF, Robins HI, Abrey LE, Prados MD, North American Brain Tumor Consortium
• A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood.
  Neuro-oncology 2008 Jakacki RI, Yates A, Blaney SM, Zhou T, Timmerman R, Ingle AM, Flom L, Prados MD, Adamson PC, Pollack IF
• Radiation is an important component of multimodality therapy for pediatric non-pineal supratentorial primitive neuroectodermal tumors.
  International journal of radiation oncology, biology, physics 2008 McBride SM, Daganzo SM, Banerjee A, Gupta N, Lamborn KR, Prados MD, Berger MS, Wara WM, Haas-Kogan DA
• Central nervous system cancers.
  Journal of the National Comprehensive Cancer Network : JNCCN 2008 Brem SS, Bierman PJ, Black P, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Glass J, Grossman SA, Heimberger AB, Junck L, Linette GP, Loeffler JJ, Maor MH,…
• Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma.
  Neuro-oncology 2008 Haas-Kogan DA, Banerjee A, Kocak M, Prados MD, Geyer JR, Fouladi M, McKnight T, Poussaint TY, Broniscer A, Blaney SM, Boyett JM, Kun LE
• Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS
• Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas.
  Neuro-oncology 2008 Lamborn KR, Yung WK, Chang SM, Wen PY, Cloughesy TF, DeAngelis LM, Robins HI, Lieberman FS, Fine HA, Fink KL, Junck L, Abrey L, Gilbert MR, Mehta M, Kuhn JG, Aldape KD, Hibberts J, Peterson PM, Prados…
• Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Kuhn JG, Chang SM, Wen PY, Cloughesy TF, Greenberg H, Schiff D, Conrad C, Fink KL, Robins HI, Mehta M, DeAngelis L, Raizer J, Hess K, Lamborn KR, Dancey J, Prados MD, North American Brain Tumor …
• Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Loghin ME, Prados MD, Wen P, Junck L, Lieberman F, Fine H, Fink KL, Metha M, Kuhn J, Lamborn K, Chang SM, Cloughesy T, DeAngelis LM, Robins IH, Aldape KD, Yung WK
• Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
  Cancer chemotherapy and pharmacology 2007 Prados MD, Yung WK, Wen PY, Junck L, Cloughesy T, Fink K, Chang S, Robins HI, Dancey J, Kuhn J
• Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Pelloski CE, Ballman KV, Furth AF, Zhang L, Lin E, Sulman EP, Bhat K, McDonald JM, Yung WK, Colman H, Woo SY, Heimberger AB, Suki D, Prados MD, Chang SM, Barker FG, Buckner JC, James CD, Aldape K
• Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2007 Chen AM, Chang S, Pouliot J, Sneed PK, Prados MD, Lamborn KR, Malec MK, McDermott MW, Berger MS, Larson DA
• Historical controls for phase II surgically based trials requiring gross total resection of glioblastoma multiforme.
  Journal of neuro-oncology 2007 Butowski N, Lamborn KR, Berger MS, Prados MD, Chang SM
• Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Kunwar S, Prados MD, Chang SM, Berger MS, Lang FF, Piepmeier JM, Sampson JH, Ram Z, Gutin PH, Gibbons RD, Aldape KD, Croteau DJ, Sherman JW, Puri RK, Cintredekin Besudotox Intraparenchymal Study Group
• Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Rubenstein JL, Fridlyand J, Abrey L, Shen A, Karch J, Wang E, Issa S, Damon L, Prados M, McDermott M, O'Brien J, Haqq C, Shuman M
• Nonsynonymous coding single-nucleotide polymorphisms spanning the genome in relation to glioblastoma survival and age at diagnosis.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Wrensch M, McMillan A, Wiencke J, Wiemels J, Kelsey K, Patoka J, Jones H, Carlton V, Miike R, Sison J, Moghadassi M, Prados M
• A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
  Journal of neuro-oncology 2006 Groves MD, Puduvalli VK, Chang SM, Conrad CA, Gilbert MR, Tremont-Lukats IW, Liu TJ, Peterson P, Schiff D, Cloughesy TF, Wen PY, Greenberg H, Abrey LE, DeAngelis LM, Hess KR, Lamborn KR, Prados MD, …
• Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Wen PY, Yung WK, Lamborn KR, Dahia PL, Wang Y, Peng B, Abrey LE, Raizer J, Cloughesy TF, Fink K, Gilbert M, Chang S, Junck L, Schiff D, Lieberman F, Fine HA, Mehta M, Robins HI, DeAngelis LM, Groves …
• Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006 Cloughesy TF, Wen PY, Robins HI, Chang SM, Groves MD, Fink KL, Junck L, Schiff D, Abrey L, Gilbert MR, Lieberman F, Kuhn J, DeAngelis LM, Mehta M, Raizer JJ, Yung WK, Aldape K, Wright J, Lamborn KR, …
• Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Pelloski CE, Lin E, Zhang L, Yung WK, Colman H, Liu JL, Woo SY, Heimberger AB, Suki D, Prados M, Chang S, Barker FG, Fuller GN, Aldape KD
• Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies.
  Neurosurgical focus 2006 Kunwar S, Chang SM, Prados MD, Berger MS, Sampson JH, Croteau D, Sherman JW, Grahn AY, Shu VS, Dul JL, Husain SR, Joshi BH, Pedain C, Puri RK
• Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival.
  Cancer research 2006 Wrensch M, Wiencke JK, Wiemels J, Miike R, Patoka J, Moghadassi M, McMillan A, Kelsey KT, Aldape K, Lamborn KR, Parsa AT, Sison JD, Prados MD
• A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
  Neuro-oncology 2006 Prados MD, Lamborn K, Yung WK, Jaeckle K, Robins HI, Mehta M, Fine HA, Wen PY, Cloughesy T, Chang S, Nicholas MK, Schiff D, Greenberg H, Junck L, Fink K, Hess K, Kuhn J, North American Brain Tumor …
• The role of up-front radiation therapy for incompletely resected pediatric WHO grade II low-grade gliomas.
  Neuro-oncology 2006 Mishra KK, Puri DR, Missett BT, Lamborn KR, Prados MD, Berger MS, Banerjee A, Gupta N, Wara WM, Haas-Kogan DA
• Gene expression and angiotropism in primary CNS lymphoma.
  Blood 2006 Rubenstein JL, Fridlyand J, Shen A, Aldape K, Ginzinger D, Batchelor T, Treseler P, Berger M, McDermott M, Prados M, Karch J, Okada C, Hyun W, Parikh S, Haqq C, Shuman M
• Diagnostic, treatment, and demographic factors influencing survival in a population-based study of adult glioma patients in the San Francisco Bay Area.
  Neuro-oncology 2006 Wrensch M, Rice T, Miike R, McMillan A, Lamborn KR, Aldape K, Prados MD
• Management of a sporadic malignant subfrontal peripheral nerve sheath tumor.
  Journal of neuro-oncology 2006 Sanchez-Mejia RO, Pham DN, Prados M, Tihan T, Cha S, El-Sayed I, McDermott MW
• Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
  Neuro-oncology 2006 Prados MD, Lamborn KR, Chang S, Burton E, Butowski N, Malec M, Kapadia A, Rabbitt J, Page MS, Fedoroff A, Xie D, Kelley SK
• Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
  The New England journal of medicine 2005 Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, …
• Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Lassman AB, Rossi MR, Raizer JJ, Razier JR, Abrey LE, Lieberman FS, Grefe CN, Lamborn K, Pao W, Shih AH, Kuhn JG, Wilson R, Nowak NJ, Cowell JK, DeAngelis LM, Wen P, Gilbert MR, Chang S, Yung WA, …
• Biomarkers to predict response to epidermal growth factor receptor inhibitors.
  Cell cycle (Georgetown, Tex.) 2005 Haas-Kogan DA, Prados MD, Lamborn KR, Tihan T, Berger MS, Stokoe D
• Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Cloughesy TF, Kuhn J, Robins HI, Abrey L, Wen P, Fink K, Lieberman FS, Mehta M, Chang S, Yung A, DeAngelis L, Schiff D, Junck L, Groves M, Paquette S, Wright J, Lamborn K, Sebti SM, Prados M
• Central nervous system cancers: Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2005 Brem SS, Bierman PJ, Black P, Blumenthal DT, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Fine HA, Friedman A, Glass J, Grossman SA, Heimberger AB, Junck L, Levin V, Loeffler JJ,…
• Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.
  Investigational new drugs 2005 Chang SM, Wen P, Cloughesy T, Greenberg H, Schiff D, Conrad C, Fink K, Robins HI, De Angelis L, Raizer J, Hess K, Aldape K, Lamborn KR, Kuhn J, Dancey J, Prados MD, North American Brain Tumor …
• High failure rate in spinal ependymomas with long-term follow-up.
  Neuro-oncology 2005 Gomez DR, Missett BT, Wara WM, Lamborn KR, Prados MD, Chang S, Berger MS, Haas-Kogan DA
• Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.
  Journal of the National Cancer Institute 2005 Haas-Kogan DA, Prados MD, Tihan T, Eberhard DA, Jelluma N, Arvold ND, Baumber R, Lamborn KR, Kapadia A, Malec M, Berger MS, Stokoe D
• A phase II study of concurrent temozolomide and cis-retinoic acid with radiation for adult patients with newly diagnosed supratentorial glioblastoma.
  International journal of radiation oncology, biology, physics 2005 Butowski N, Prados MD, Lamborn KR, Larson DA, Sneed PK, Wara WM, Malec M, Rabbitt J, Page M, Chang SM
• Brain metastases of breast cancer.
  Expert review of anticancer therapy 2005 Melisko ME, Kunwar S, Prados M, Berger MS, Park JW
• Prognostic significance of intracranial dissemination of glioblastoma multiforme in adults.
  Journal of neurosurgery 2005 Parsa AT, Wachhorst S, Lamborn KR, Prados MD, McDermott MW, Berger MS, Chang SM
• Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.
  AJNR. American journal of neuroradiology 2005 Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP
• Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma.
  Journal of neurosurgery 2005 Parney IF, Kunwar S, McDermott M, Berger M, Prados M, Cha S, Croteau D, Puri RK, Chang SM
• Phase I clinical trial of mafosfamide in infants and children aged 3 years or younger with newly diagnosed embryonal tumors: a pediatric brain tumor consortium study (PBTC-001).
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Blaney SM, Boyett J, Friedman H, Gajjar A, Geyer R, Horowtiz M, Hunt D, Kieran M, Kun L, Packer R, Phillips P, Pollack IF, Prados M, Heideman R
• Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
  Cancer investigation 2005 Macdonald DR, Kiebert G, Prados M, Yung A, Olson J
• Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.
  Investigational new drugs 2004 Chang SM, Kuhn J, Wen P, Greenberg H, Schiff D, Conrad C, Fink K, Robins HI, Cloughesy T, De Angelis L, Razier J, Hess K, Dancey J, Prados MD, North American Brain Tumor Consortium And The National …
• Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004 Puduvalli VK, Yung WK, Hess KR, Kuhn JG, Groves MD, Levin VA, Zwiebel J, Chang SM, Cloughesy TF, Junck L, Wen P, Lieberman F, Conrad CA, Gilbert MR, Meyers CA, Liu V, Mehta MP, Nicholas MK, Prados M, …
• Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2004 Chang SM, Lamborn KR, Malec M, Larson D, Wara W, Sneed P, Rabbitt J, Page M, Nicholas MK, Prados MD
• Prognostic factors for survival of patients with glioblastoma: recursive partitioning analysis.
  Neuro-oncology 2004 Lamborn KR, Chang SM, Prados MD
• Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
  Cancer 2004 Chang SM, Prados MD, Yung WK, Fine H, Junck L, Greenberg H, Robins HI, Mehta M, Fink KL, Jaeckle KA, Kuhn J, Hess K, Schold C
• Permanent iodine 125 brachytherapy in patients with progressive or recurrent glioblastoma multiforme.
  Neuro-oncology 2004 Larson DA, Suplica JM, Chang SM, Lamborn KR, McDermott MW, Sneed PK, Prados MD, Wara WM, Nicholas MK, Berger MS
• Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: final report of RTOG 9404.
  International journal of radiation oncology, biology, physics 2004 Prados MD, Seiferheld W, Sandler HM, Buckner JC, Phillips T, Schultz C, Urtasun R, Davis R, Gutin P, Cascino TL, Greenberg HS, Curran WJ
• Temozolomide in the treatment of recurrent malignant glioma.
  Cancer 2004 Chang SM, Theodosopoulos P, Lamborn K, Malec M, Rabbitt J, Page M, Prados MD
• O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas.
  Neuro-oncology 2004 Schold SC, Kokkinakis DM, Chang SM, Berger MS, Hess KR, Schiff D, Robins HI, Mehta MP, Fink KL, Davis RL, Prados MD
• Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
  Neuro-oncology 2004 Prados MD, Yung WK, Jaeckle KA, Robins HI, Mehta MP, Fine HA, Wen PY, Cloughesy TF, Chang SM, Nicholas MK, Schiff D, Greenberg HS, Junck L, Fink KL, Hess KR, Kuhn J, North American Brain Tumor …
• Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
  Neuro-oncology 2004 Prados MD, Yung WK, Fine HA, Greenberg HS, Junck L, Chang SM, Nicholas MK, Robins HI, Mehta MP, Fink KL, Jaeckle KA, Kuhn J, Hess KR, Schold SC, North American Brain Tumor Consortium study
• Volume of residual disease as a predictor of outcome in adult patients with recurrent supratentorial glioblastomas multiforme who are undergoing chemotherapy.
  Journal of neurosurgery 2004 Keles GE, Lamborn KR, Chang SM, Prados MD, Berger MS
• Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: a phase I/II multi-institutional trial.
  Journal of neuro-oncology 2003 Prados MD, McDermott M, Chang SM, Wilson CB, Fick J, Culver KW, Van Gilder J, Keles GE, Spence A, Berger M
• A study of a different dose-intense infusion schedule of phenylacetate in patients with recurrent primary brain tumors consortium report.
  Investigational new drugs 2003 Chang SM, Kuhn JG, Ian Robins H, Clifford Schold S, Spence AM, Berger MS, Mehta MP, Pollack I, Gilbert M, Prados MD
• Gliomatosis cerebri: a review of 22 cases.
  Neurosurgery 2003 Vates GE, Chang S, Lamborn KR, Prados M, Berger MS
• Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma.
  Journal of neuro-oncology 2003 Weber F, Asher A, Bucholz R, Berger M, Prados M, Chang S, Bruce J, Hall W, Rainov NG, Westphal M, Warnick RE, Rand RW, Floeth F, Rommel F, Pan H, Hingorani VN, Puri RK
• Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Lang FF, Bruner JM, Fuller GN, Aldape K, Prados MD, Chang S, Berger MS, McDermott MW, Kunwar SM, Junck LR, Chandler W, Zwiebel JA, Kaplan RS, Yung WK
• Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Jaeckle KA, Hess KR, Yung WK, Greenberg H, Fine H, Schiff D, Pollack IF, Kuhn J, Fink K, Mehta M, Cloughesy T, Nicholas MK, Chang S, Prados M, North American Brain Tumor Consortium
• Radiation therapy for intracranial germ cell tumors.
  International journal of radiation oncology, biology, physics 2003 Haas-Kogan DA, Missett BT, Wara WM, Donaldson SS, Lamborn KR, Prados MD, Fisher PG, Huhn SL, Fisch BM, Berger MS, Le QT
• Repeated operations for infiltrative low-grade gliomas without intervening therapy.
  Journal of neurosurgery 2003 Schmidt MH, Berger MS, Lamborn KR, Aldape K, McDermott MW, Prados MD, Chang SM
• A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma.
  Neuro-oncology 2003 Prados MD, Schold SC, Fine HA, Jaeckle K, Hochberg F, Mechtler L, Fetell MR, Phuphanich S, Feun L, Janus TJ, Ford K, Graney W
• Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Levin VA, Hess KR, Choucair A, Flynn PJ, Jaeckle KA, Kyritsis AP, Yung WK, Prados MD, Bruner JM, Ictech S, Gleason MJ, Kim HW
• Anaplastic oligodendrogliomas: prognostic factors for tumor recurrence and survival.
  Oncology 2003 Puduvalli VK, Hashmi M, McAllister LD, Levin VA, Hess KR, Prados M, Jaeckle KA, Yung WK, Buys SS, Bruner JM, Townsend JJ, Davis R, Sawaya R, Kyritsis AP
• Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma.
  International journal of radiation oncology, biology, physics 2002 Larson DA, Prados M, Lamborn KR, Smith V, Sneed PK, Chang S, Nicholas KM, Wara WM, Devriendt D, Kunwar S, Berger M, McDermott MW
• A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.
  Neuro-oncology 2002 Robins HI, Chang SM, Prados MD, Yung WK, Hess K, Schiff D, Greenberg H, Fink K, Nicolas K, Kuhn JG, Cloughesy T, Junck L, Mehta M
• Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2002 Burton EC, Lamborn KR, Forsyth P, Scott J, O'Campo J, Uyehara-Lock J, Prados M, Berger M, Passe S, Uhm J, O'Neill BP, Jenkins RB, Aldape KD
• Age and radiation response in glioblastoma multiforme.
  Neurosurgery 2001 Barker FG, Chang SM, Larson DA, Sneed PK, Wara WM, Wilson CB, Prados MD
• Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival.
  Cancer research 2001 Kunwar S, Mohapatra G, Bollen A, Lamborn KR, Prados M, Feuerstein BG
• EGFR overexpression and radiation response in glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2001 Barker FG, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS, Chen P, Israel MA, Aldape KD
• Temozolomide in combination with other cytotoxic agents.
  Seminars in oncology 2001 Prados M
• Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery.
  AJNR. American journal of neuroradiology 2001 Graves EE, Nelson SJ, Vigneron DB, Verhey L, McDermott M, Larson D, Chang S, Prados MD, Dillon WP
• A Phase II study of paclitaxel in patients with recurrent malignant glioma using different doses depending upon the concomitant use of anticonvulsants: a North American Brain Tumor Consortium report.
  Cancer 2001 Chang SM, Kuhn JG, Robins HI, Schold SC, Spence AM, Berger MS, Mehta M, Pollack IF, Rankin C, Prados MD
• Phase III trial of accelerated hyperfractionation with or without difluromethylornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2001 Prados MD, Wara WM, Sneed PK, McDermott M, Chang SM, Rabbitt J, Page M, Malec M, Davis RL, Gutin PH, Lamborn K, Wilson CB, Phillips TL, Larson DA
• Malignant gliomas.
  Current treatment options in oncology 2000 Burton EC, Prados MD
• Biology and treatment of malignant glioma.
  Seminars in oncology 2000 Prados MD, Levin V
• Future directions in the treatment of malignant gliomas with temozolomide.
  Seminars in oncology 2000 Prados MD
• A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
  Neurosurgery 2000 Graves EE, Nelson SJ, Vigneron DB, Chin C, Verhey L, McDermott M, Larson D, Sneed PK, Chang S, Prados MD, Lamborn K, Dillon WP
• A phase 3 randomized study of radiotherapy plus procarbazine, CCNU, and vincristine (PCV) with or without BUdR for the treatment of anaplastic astrocytoma: a preliminary report of RTOG 9404.
  International journal of radiation oncology, biology, physics 1999 Prados MD, Scott C, Sandler H, Buckner JC, Phillips T, Schultz C, Urtasun R, Davis R, Gutin P, Cascino TL, Greenberg HS, Curran WJ
• Procarbazine, lomustine, and vincristine (PCV) chemotherapy for anaplastic astrocytoma: A retrospective review of radiation therapy oncology group protocols comparing survival with carmustine or PCV adjuvant chemotherapy.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999 Prados MD, Scott C, Curran WJ, Nelson DF, Leibel S, Kramer S
• Radiopotentiation of human brain tumor cells by sodium phenylacetate.
  Cancer letters 1999 Ozawa T, Lu RM, Hu LJ, Lamborn KR, Prados MD, Deen DF
• Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: correlation with radiation treatment outcome.
  Clinical cancer research : an official journal of the American Association for Cancer Research 1999 Huhn SL, Mohapatra G, Bollen A, Lamborn K, Prados MD, Feuerstein BG
• New chemotherapy options for the treatment of malignant gliomas.
  Current opinion in oncology 1999 Burton E, Prados M
• Late radiation injury following hyperfractionated craniospinal radiotherapy for primitive neuroectodermal tumor.
  International journal of radiation oncology, biology, physics 1999 Russo C, Fischbein N, Grant E, Prados MD
• Phase II study of phenylacetate in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999 Chang SM, Kuhn JG, Robins HI, Schold SC, Spence AM, Berger MS, Mehta MP, Bozik ME, Pollack I, Schiff D, Gilbert M, Rankin C, Prados MD
• Final report on the University of California-San Francisco experience with bromodeoxyuridine labeling index as a prognostic factor for the survival of glioma patients.
  Cancer 1999 Lamborn KR, Prados MD, Kaplan SB, Davis RL
• Hyperfractionated craniospinal radiation therapy for primitive neuroectodermal tumors: results of a Phase II study.
  International journal of radiation oncology, biology, physics 1999 Prados MD, Edwards MS, Chang SM, Russo C, Davis R, Rabbitt J, Page M, Lamborn K, Wara WM
• Primary central nervous system tumors: advances in knowledge and treatment.
  CA: a cancer journal for clinicians 1998 Prados MD, Berger MS, Wilson CB
• Phase I study of paclitaxel in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Chang SM, Kuhn JG, Rizzo J, Robins HI, Schold SC, Spence AM, Berger MS, Mehta MP, Bozik ME, Pollack I, Gilbert M, Fulton D, Rankin C, Malec M, Prados MD
• High dose oral tamoxifen and subcutaneous interferon alpha-2a for recurrent glioma.
  Journal of neuro-oncology 1998 Chang SM, Barker FG, Huhn SL, Nicholas MK, Page M, Rabbitt J, Prados MD
• Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade.
  Genes, chromosomes & cancer 1998 Mohapatra G, Bollen AW, Kim DH, Lamborn K, Moore DH, Prados MD, Feuerstein BG
• Influence of bromodeoxyuridine radiosensitization on malignant glioma patient survival: a retrospective comparison of survival data from the Northern California Oncology Group (NCOG) and Radiation Therapy Oncology Group trials (RTOG) for glioblastoma multiforme and anaplastic astrocytoma.
  International journal of radiation oncology, biology, physics 1998 Prados MD, Scott CB, Rotman M, Rubin P, Murray K, Sause W, Asbell S, Comis R, Curran W, Nelson J, Davis RL, Levin VA, Lamborn K, Phillips TL
• Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 1998 Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH
• Chemotherapy of brain tumors.
  Seminars in surgical oncology 1998 Prados MD, Russo C
• Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.
  International journal of radiation oncology, biology, physics 1998 Prados MD, Larson DA, Lamborn K, McDermott MW, Sneed PK, Wara WM, Chang SM, Mack EE, Krouwer HG, Chandler KL, Warnick RE, Davis RL, Rabbitt JE, Malec M, Levin VA, Gutin PH, Phillips TL, Wilson CB
• Volume MRI and MRSI techniques for the quantitation of treatment response in brain tumors: presentation of a detailed case study.
  Journal of magnetic resonance imaging : JMRI 1997 Nelson SJ, Huhn S, Vigneron DB, Day MR, Wald LL, Prados M, Chang S, Gutin PH, Sneed PK, Verhey L, Hawkins RA, Dillon WP
• Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
  Journal of neurosurgery 1997 Wald LL, Nelson SJ, Day MR, Noworolski SE, Henry RG, Huhn SL, Chang S, Prados MD, Sneed PK, Larson DA, Wara WM, McDermott M, Dillon WP, Gutin PH, Vigneron DB
• Age and the risk of anaplasia in magnetic resonance-nonenhancing supratentorial cerebral tumors.
  Cancer 1997 Barker FG, Chang SM, Huhn SL, Davis RL, Gutin PH, McDermott MW, Wilson CB, Prados MD
• Adult medulloblastoma: an analysis of survival and prognostic factors.
  The cancer journal from Scientific American 1997 Le QT, Weil MD, Wara WM, Lamborn KR, Prados MD, Edwards MS, Gutin PH
• Neon heavy charged particle radiotherapy of glioblastoma of the brain.
  International journal of radiation oncology, biology, physics 1997 Castro JR, Phillips TL, Prados M, Gutin P, Larson DA, Petti PL, Daftari IK, Collier JM, Lillis-Hearne P
• Treatment of pediatric low-grade gliomas with a nitrosourea-based multiagent chemotherapy regimen.
  Journal of neuro-oncology 1997 Prados MD, Edwards MS, Rabbitt J, Lamborn K, Davis RL, Levin VA
• Neuropsychological sequelae of medulloblastoma in adults.
  International journal of radiation oncology, biology, physics 1997 Kramer JH, Crowe AB, Larson DA, Sneed PK, Gutin PH, McDermott MW, Prados MD
• Alignment of volume MR images and high resolution [18F]fluorodeoxyglucose PET images for the evaluation of patients with brain tumors.
  Journal of computer assisted tomography 1997 Nelson SJ, Day MR, Buffone PJ, Wald LL, Budinger TF, Hawkins R, Dillon WP, Huhn S, Prados MD, Chang S, Vigneron DB
• 18-Fluorodeoxyglucose uptake and survival of patients with suspected recurrent malignant glioma.
  Cancer 1997 Barker FG, Chang SM, Valk PE, Pounds TR, Prados MD
• Intravenous carboplatin for recurrent gliomas. A dose-escalating phase II trial.
  American journal of clinical oncology 1996 Prados MD, Warnick RE, Mack EE, Chandler KL, Rabbitt J, Page M, Malec M
• Treatment of high-risk medulloblastoma and other primitive neuroectodermal tumors with reduced dose craniospinal radiation therapy and multi-agent nitrosourea-based chemotherapy.
  Pediatric neurosurgery 1996 Prados MD, Wara W, Edwards MS, Ater J, Rabbit J, Lamborn K, Davis R, Levin VA
• Long-term follow-up after high-activity 125I brachytherapy for pediatric brain tumors.
  Pediatric neurosurgery 1996 Sneed PK, Russo C, Scharfen CO, Prados MD, Malec MK, Larson DA, Lamborn KR, Lamb SA, Voss B, Weaver KA, Phillips TL, Gutin PH, Wara WM, Edwards MS
• Demonstration of brachytherapy boost dose-response relationships in glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 1996 Sneed PK, Lamborn KR, Larson DA, Prados MD, Malec MK, McDermott MW, Weaver KA, Phillips TL, Wara WM, Gutin PH
• Bromodeoxyuridine labeling index in glioblastoma multiforme: relation to radiation response, age, and survival.
  International journal of radiation oncology, biology, physics 1996 Barker FG, Prados MD, Chang SM, Davis RL, Gutin PH, Lamborn KR, Larson DA, McDermott MW, Sneed PK, Wilson CB
• Radiation response and survival time in patients with glioblastoma multiforme.
  Journal of neurosurgery 1996 Barker FG, Prados MD, Chang SM, Gutin PH, Lamborn KR, Larson DA, Malec MK, McDermott MW, Sneed PK, Wara WM, Wilson CB
• Radiologic classification of brain stem tumors: correlation of magnetic resonance imaging appearance with clinical outcome.
  Pediatric neurosurgery 1996 Fischbein NJ, Prados MD, Wara W, Russo C, Edwards MS, Barkovich AJ
• Pineoblastoma in adults.
  Neurosurgery 1995 Chang SM, Lillis-Hearne PK, Larson DA, Wara WM, Bollen AW, Prados MD
• Constitutional p53 mutations associated with brain tumors in young adults.
  Cancer genetics and cytogenetics 1995 Chen P, Iavarone A, Fick J, Edwards M, Prados M, Israel MA
• Medulloblastoma in adults.
  International journal of radiation oncology, biology, physics 1995 Prados MD, Warnick RE, Wara WM, Larson DA, Lamborn K, Wilson CB
• Radiation therapy for primary intracranial germ-cell tumors.
  International journal of radiation oncology, biology, physics 1995 Wolden SL, Wara WM, Larson DA, Prados MD, Edwards MS, Sneed PK
• Fetal dose estimates for radiotherapy of brain tumors during pregnancy.
  International journal of radiation oncology, biology, physics 1995 Sneed PK, Albright NW, Wara WM, Prados MD, Wilson CB
• Chemotherapy for gliomas.
  Current opinion in oncology 1995 Chang SM, Prados MD
• Large effect of age on the survival of patients with glioblastoma treated with radiotherapy and brachytherapy boost.
  Neurosurgery 1995 Sneed PK, Prados MD, McDermott MW, Larson DA, Malec MK, Lamborn KR, Davis RL, Weaver KA, Wara WM, Phillips TL
• The treatment of brain stem and thalamic gliomas with 78 Gy of hyperfractionated radiation therapy.
  International journal of radiation oncology, biology, physics 1995 Prados MD, Wara WM, Edwards MS, Larson DA, Lamborn K, Levin VA
• Infiltrative astrocytomas of the thalamus.
  Journal of neurosurgery 1995 Krouwer HG, Prados MD
• Sarcomas subsequent to cranial irradiation.
  Neurosurgery 1995 Chang SM, Barker FG, Larson DA, Bollen AW, Prados MD
• Carboplatin hypersensitivity in children. A report of five patients with brain tumors.
  Cancer 1995 Chang SM, Fryberger S, Crouse V, Tilford D, Prados MD
• Surgery for low-grade glioma: rationale for early intervention.
  Clinical neurosurgery 1995 Wilson CB, Prados MD
• Pattern of recurrence of medulloblastoma after low-dose craniospinal radiotherapy.
  International journal of radiation oncology, biology, physics 1994 Wara WM, Le QT, Sneed PK, Larson DA, Prados MD, Levin VA, Edwards MS, Weil MD
• Patterns of recurrence of glioblastoma multiforme after external irradiation followed by implant boost.
  International journal of radiation oncology, biology, physics 1994 Sneed PK, Gutin PH, Larson DA, Malec MK, Phillips TL, Prados MD, Scharfen CO, Weaver KA, Wara WM
• Treatment options and prognosis for multicentric juvenile pilocytic astrocytoma.
  Journal of neurosurgery 1994 Mamelak AN, Prados MD, Obana WG, Cogen PH, Edwards MS
• Identical twins with Ollier's disease and intracranial gliomas: case report.
  Neurosurgery 1994 Chang S, Prados MD
• Hyperfractionated craniospinal radiation therapy for primitive neuroectodermal tumors: early results of a pilot study.
  International journal of radiation oncology, biology, physics 1994 Prados MD, Wara WM, Edwards MS, Cogen PH
• A phase II study of intravenous carboplatin for the treatment of recurrent gliomas.
  Journal of neuro-oncology 1994 Warnick RE, Prados MD, Mack EE, Chandler KL, Doz F, Rabbitt JE, Malec MK
• Proliferative potential and prognostic evaluation of low-grade astrocytomas.
  Journal of neuro-oncology 1994 Ito S, Chandler KL, Prados MD, Lamborn K, Wynne J, Malec MK, Wilson CB, Davis RL, Hoshino T
• The prognostic implications of histologic classification and bromodeoxyuridine labeling index of mixed gliomas.
  Journal of neuro-oncology 1994 Wacker MR, Hoshino T, Ahn DK, Davis RL, Prados MD
• Gangliogliomas: a clinicopathological study of 25 cases and review of the literature.
  Journal of neuro-oncology 1993 Krouwer HG, Davis RL, McDermott MW, Hoshino T, Prados MD
• Long-term survival in patients with glioblastoma multiforme.
  Neurosurgery 1993 Chandler KL, Prados MD, Malec M, Wilson CB
• Intracranial myxopapillary ependymoma: case report.
  Journal of neuro-oncology 1993 Warnick RE, Raisanen J, Adornato BT, Prados MD, Davis RL, Larson DA, Gutin PH
• Prognostic significance of the proliferative potential of intracranial gliomas measured by bromodeoxyuridine labeling.
  International journal of cancer 1993 Hoshino T, Ahn D, Prados MD, Lamborn K, Wilson CB
• Quality of life self-reports from 200 brain tumor patients: comparisons with Karnofsky performance scores.
  Journal of neuro-oncology 1992 Mackworth N, Fobair P, Prados MD
• Proliferative characteristics of juvenile pilocytic astrocytomas determined by bromodeoxyuridine labeling.
  Neurosurgery 1992 Ito S, Hoshino T, Shibuya M, Prados MD, Edwards MS, Davis RL
• Cell kinetics of medulloblastomas.
  Cancer 1992 Ito S, Hoshino T, Prados MD, Edwards MS
• Diffuse leptomeningeal involvement by a ganglioglioma in a child. Case report.
  Journal of neurosurgery 1992 Wacker MR, Cogen PH, Etzell JE, Daneshvar L, Davis RL, Prados MD
• Proliferative potential and outcome in pediatric astrocytic tumors.
  Journal of neuro-oncology 1992 Prados MD, Krouwer HG, Edwards MS, Cogen PH, Davis RL, Hoshino T
• Treatment of recurrent gliomas and metastatic brain tumors with a polydrug protocol designed to combat nitrosourea resistance.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992 Levin VA, Prados MD
• Meningiomas: clinical implications of a high proliferative potential determined by bromodeoxyuridine labeling.
  Neurosurgery 1992 Shibuya M, Hoshino T, Ito S, Wacker MR, Prados MD, Davis RL, Wilson CB
• A comparison of CT contrast enhancement and BUDR labeling indices in moderately and highly anaplastic astrocytomas of the cerebral hemispheres.
  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1992 McDermott MW, Krouwer HG, Asai A, Ito S, Hoshino T, Prados MD
• Cell kinetic analysis of human brain tumors by in situ double labelling with bromodeoxyuridine and iododeoxyuridine.
  International journal of cancer 1992 Hoshino T, Ito S, Asai A, Shibuya M, Prados MD, Dodson BA, Davis RL, Wilson CB
• Brachytherapy of brain tumors.
  Stereotactic and functional neurosurgery 1992 Sneed PK, Gutin PH, Prados MD, Phillips TL, Weaver KA, Wara WM, Larson DA
• High activity iodine-125 interstitial implant for gliomas.
  International journal of radiation oncology, biology, physics 1992 Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Prados MD, Weaver KA, Malec M, Acord P, Lamborn KR
• Highly anaplastic astrocytoma: a review of 357 patients treated between 1977 and 1989.
  International journal of radiation oncology, biology, physics 1992 Prados MD, Gutin PH, Phillips TL, Wara WM, Larson DA, Sneed PK, Davis RL, Ahn DK, Lamborn K, Wilson CB
• Hyperfractionated radiation therapy for gliomas of the brainstem in children and in adults.
  International journal of radiation oncology, biology, physics 1992 Shrieve DC, Wara WM, Edwards MS, Sneed PK, Prados MD, Cogen PH, Larson DA, Levin VA
• Interstitial brachytherapy for newly diagnosed patients with malignant gliomas: the UCSF experience.
  International journal of radiation oncology, biology, physics 1992 Prados MD, Gutin PH, Phillips TL, Wara WM, Sneed PK, Larson DA, Lamb SA, Ham B, Malec MK, Wilson CB
• Late manifestations of esthesioneuroblastomas in the central nervous system: report of two cases.
  Neurosurgery 1992 Mack EE, Prados MD, Wilson CB
• Thermoradiotherapy of recurrent malignant brain tumors.
  International journal of radiation oncology, biology, physics 1992 Sneed PK, Gutin PH, Stauffer PR, Phillips TL, Prados MD, Weaver KA, Suen S, Lamb SA, Ham B, Ahn DK
• Desmoplastic medulloblastoma metastatic to the pancreas: case report.
  Neurosurgery 1991 Krouwer HG, Vollmerhausen J, White J, Prados MD
• Evaluation of bromodeoxyuridine in glioblastoma multiforme: a Northern California Cancer Center Phase II study.
  International journal of radiation oncology, biology, physics 1991 Phillips TL, Levin VA, Ahn DK, Gutin PH, Davis RL, Wilson CB, Prados MD, Wara WM, Flam MS
• External irradiation followed by an interstitial high activity iodine-125 implant "boost" in the initial treatment of malignant gliomas: NCOG study 6G-82-2.
  International journal of radiation oncology, biology, physics 1991 Gutin PH, Prados MD, Phillips TL, Wara WM, Larson DA, Leibel SA, Sneed PK, Levin VA, Weaver KA, Silver P
• Management of chiasmal and hypothalamic gliomas of infancy and childhood with chemotherapy.
  Journal of neurosurgery 1991 Petronio J, Edwards MS, Prados M, Freyberger S, Rabbitt J, Silver P, Levin VA
• Hyperfractionated irradiation for adults with brainstem gliomas.
  International journal of radiation oncology, biology, physics 1991 Linstadt DE, Edwards MS, Prados M, Larson DA, Wara WM
• Gemistocytic astrocytomas: a reappraisal.
  Journal of neurosurgery 1991 Krouwer HG, Davis RL, Silver P, Prados M
• Intradural chordoma of the tentorium cerebelli. Case report.
  Journal of neurosurgery 1991 Warnick RE, Raisanen J, Kaczmar T, Davis RL, Prados MD
• Interstitial irradiation and hyperthermia for the treatment of recurrent malignant brain tumors.
  Neurosurgery 1991 Sneed PK, Stauffer PR, Gutin PH, Phillips TL, Suen S, Weaver KA, Lamb SA, Ham B, Prados MD, Larson DA
• Hypothalamic hamartoma associated with Laurence-Moon-Biedl syndrome. Case report and review of the literature.
  Pediatric neurosurgery 1991 Diaz LL, Grech KF, Prados MD
• Postoperative radiotherapy and radiotherapy combined with CCNU chemotherapy for treatment of brain gliomas.
  Journal of neuro-oncology 1990 Krouwer D, McDermott M, Prados M
• Reevaluation of procarbazine for the treatment of recurrent malignant central nervous system tumors.
  Cancer 1989 Rodriguez LA, Prados M, Silver P, Levin VA
• Prognostic implications of the bromodeoxyuridine labeling index of human gliomas.
  Journal of neurosurgery 1989 Hoshino T, Prados M, Wilson CB, Cho KG, Lee KS, Davis RL
• Treatment of recurrent gliomas with 1,3-bis(2-chloroethyl)-1-nitrosourea and alpha-difluoromethylornithine.
  Neurosurgery 1989 Prados M, Rodriguez L, Chamberlain M, Silver P, Levin V
• Hyperfractionated radiation therapy for brain-stem glioma: a phase I-II trial.
  Journal of neurosurgery 1989 Edwards MS, Wara WM, Urtasun RC, Prados M, Levin VA, Fulton D, Wilson CB, Hannigan J, Silver P
• Phase I/II study of intraventricular and intrathecal ACNU for leptomeningeal neoplasia.
  Cancer chemotherapy and pharmacology 1989 Levin VA, Chamberlain M, Silver P, Rodriguez L, Prados M
• A phase I/II study of 24 hour intravenous AZQ in recurrent primary brain tumors.
  Journal of neuro-oncology 1988 Chamberlain MC, Prados MD, Silver P, Levin VA
• Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine.
  Neurosurgery 1988 Rodriguez LA, Prados M, Fulton D, Edwards MS, Silver P, Levin V
• A phase II trial of oral melphalan in recurrent primary brain tumors.
  American journal of clinical oncology 1988 Chamberlain MC, Prados MD, Silver P, Levin VA
• Phase II study of spirohydantoin mustard for the treatment of recurrent malignant gliomas.
  Cancer treatment reports 1987 Prados M, Rodriguez L, Seager M, Silver P, Levin V
• Current management of brain stem gliomas.
  Pediatric neuroscience 1987 Edwards MS, Prados M
• Malignant supratentorial gliomas in childhood.
  Pediatric neuroscience 1987 Prados M, Levin V