Michael Peters, MD
Associate Professor
Medicine
School of Medicine

His clinical activities include critical care medicine, attending in the UCSF pulmonary function laboratory, and an outpatient practice focused on the care of patients with severe asthma. He directs a research program at the UCSF Parnassus Heights campus focused on identifying the molecular mechanisms that drive severe asthma.

• Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program.
  American journal of respiratory and critical care medicine 2023 Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, Erzurum SC, Lempel J, Moore WC, …
• Reply to Nie et al. and Bhammar et al.
  American journal of respiratory and critical care medicine 2023 Peters MC, Schiebler ML, Mauger DT, Fahy JV
• The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.
  American journal of respiratory and critical care medicine 2022 Peters MC, Schiebler ML, Cardet JC, Johansson MW, Sorkness R, DeBoer MD, Bleecker ER, Meyers DA, Castro M, Sumino K, Erzurum SC, Tattersall MC, Zein JG, Hastie AT, Moore W, Levy BD, Israel E, Phillips…
• Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.
  The European respiratory journal 2022 Al-Shaikhly T, Murphy RC, Parker A, Lai Y, Altman MC, Larmore M, Altemeier WA, Frevert CW, Debley JS, Piliponsky AM, Ziegler SF, Peters MC, Hallstrand TS
• Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time.
  American journal of respiratory and critical care medicine 2022 Tang M, Elicker BM, Henry T, Gierada DS, Schiebler ML, Huang BK, Peters MC, Castro M, Hoffman EA, Fain SB, Ash SY, Choi J, Hall C, Phillips BR, Mauger DT, Denlinger LC, Jarjour NN, Israel E, …
• Novel potential treatable traits in asthma: Where is the research taking us?
  The journal of allergy and clinical immunology. Global 2022 Carr TF, Peters MC
• Obesity alters pathology and treatment response in inflammatory disease.
  Nature 2022 Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, …
• The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions.
  The Journal of allergy and clinical immunology 2021 Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, …
• Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.
  American journal of respiratory and critical care medicine 2021 Khatri SB, Iaccarino JM, Barochia A, Soghier I, Akuthota P, Brady A, Covar RA, Debley JS, Diamant Z, Fitzpatrick AM, Kaminsky DA, Kenyon NJ, Khurana S, Lipworth BJ, McCarthy K, Peters M, Que LG, Ross …
• Update in Adult Asthma 2020.
  American journal of respiratory and critical care medicine 2021 Halayko AJ, Pascoe CD, Gereige JD, Peters MC, Cohen RT, Woodruff PG
• Benefits of Airway Androgen Receptor Expression in Human Asthma.
  American journal of respiratory and critical care medicine 2021 Zein JG, McManus JM, Sharifi N, Erzurum SC, Marozkina N, Lahm T, Giddings O, Davis MD, DeBoer MD, Comhair SA, Bazeley P, Kim HJ, Busse W, Calhoun W, Castro M, Chung KF, Fahy JV, Israel E, Jarjour NN, …
• Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma.
  American journal of respiratory and critical care medicine 2021 Denlinger LC, Phillips BR, Sorkness RL, Bleecker ER, Castro M, DeBoer MD, Fitzpatrick AM, Hastie AT, Gaffin JM, Moore WC, Peters MC, Peters SP, Phipatanakul W, Cardet JC, Erzurum SC, Fahy JV, Fajt ML,…
• The association of plasma IL-6 with measures of asthma morbidity in a moderate-severe pediatric cohort aged 6-18 years.
  The journal of allergy and clinical immunology. In practice 2021 Permaul P, Peters MC, Petty CR, Cardet JC, Ly NP, Ramratnam SK, Ross K, Fitzpatrick A, Israel E, Bacharier LB, Phipatanakul W, National Heart, Lung, and Blood Institute Severe Asthma Research Program-…
• PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment.
  The Journal of allergy and clinical immunology 2021 Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, …
• QCT-based Measures Of Airway Narrowing And Shape Changes Associated With Endobronchial Biopsy Tissue Measures of Airway Remodeling And Clinical Outcomes In Asthma.
  Journal of Allergy and Clinical Immunology 2021 Jiwoong Choi, Jonathan Boomer, In Kyu Lee, Fred Shi, Stephanie Christenson, Jenna Nguyen, Leonard Bacharier, Prescott Woodruff, Michael Peters, Sanghun Choi, Ching-Long Lin, Mario Castro
• Erratum: COVID-19-related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids.
  American journal of respiratory and critical care medicine 2020 Peters MC, Fahy JV
• Reply to Nannini and to Lipworth et al.
  American journal of respiratory and critical care medicine 2020 Peters MC, Fahy JV, Denlinger LC
• Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency.
  American journal of respiratory and critical care medicine 2020 Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, Fahy JV, Denlinger LC
• The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.
  Journal of biopharmaceutical statistics 2020 Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, …
• An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2020 Kerr SC, Gonzalez JR, Schanin J, Peters MC, Lambrecht BN, Brock EC, Charbit A, Ansel KM, Youngblood BA, Fahy JV
• COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.
  American journal of respiratory and critical care medicine 2020 Peters MC, Sajuthi S, Deford P, Christenson S, Rios CL, Montgomery MT, Woodruff PG, Mauger DT, Erzurum SC, Johansson MW, Denlinger LC, Jarjour NN, Castro M, Hastie AT, Moore W, Ortega VE, Bleecker ER,…
• Diagnosis and Management of T2-High Asthma.
  The journal of allergy and clinical immunology. In practice 2020 Coverstone AM, Seibold MA, Peters MC
• Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma.
  Lancet (London, England) 2020 Peters MC, Wenzel SE
• Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
  Diabetes care 2019 Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, Knip M, Jacobsen L,…
• Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.
  The Journal of clinical investigation 2019 Altman MC, Lai Y, Nolin JD, Long S, Chen CC, Piliponsky AM, Altemeier WA, Larmore M, Frevert CW, Mulligan MS, Ziegler SF, Debley JS, Peters MC, Hallstrand TS
• Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.
  The Journal of allergy and clinical immunology 2019 Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, Meyers DA, Fahy JV, Bleecker ER, National …
• Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
  American journal of respiratory and critical care medicine 2019 Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, …
• Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials. Bridging Clinical and Patient Perspectives.
  American journal of respiratory and critical care medicine 2019 Siddiqui S, Denlinger LC, Fowler SJ, Akuthota P, Shaw DE, Heaney LG, Brown L, Castro M, Winders TA, Kraft M, Wagers S, Peters MC, Pavord ID, Walker S, Jarjour NN
• ALX receptor ligands define a biochemical endotype for severe asthma.
  JCI insight 2018 Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, …
• Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.
  The Journal of allergy and clinical immunology 2018 Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, …
• Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.
  The Journal of clinical investigation 2018 Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel …
• Sputum Mast Cells and Eosinophils Identify Asthmatics with Lower Lung Function and Proneness to Exacerbations.
  Journal of Allergy and Clinical Immunology 2018 Merritt L. Fajt, Michael Peters, Eugene R. Bleecker, Juan Carlos Cardet, Mario Castro, Suzy Comhair, Andrea Coverstone, Loren C. Denlinger, Serpil C. Erzurum, Annette T. Hastie, Elliot Israel, Nizar N…
• Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control.
  Chest 2017 Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC, National Heart Lung and Blood Institute’s Severe …
• Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.
  The journal of allergy and clinical immunology. In practice 2017 Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, …
• ALX receptor ligands define a biochemical endotype for severe asthma.
  JCI insight 2017 Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, …
• Natural killer cell-mediated inflammation resolution is disabled in severe asthma.
  Science immunology 2017 Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone …
• Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.
  American journal of respiratory and critical care medicine 2017 Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, …
• Biomarkers of Airway Type-2 Inflammation and Integrating Complex Phenotypes to Endotypes in Asthma.
  Current allergy and asthma reports 2016 Peters MC, Nguyen ML, Dunican EM
• IL1RL1 asthma risk variants regulate airway type 2 inflammation.
  JCI insight 2016 Gordon ED, Palandra J, Wesolowska-Andersen A, Ringel L, Rios CL, Lachowicz-Scroggins ME, Sharp LZ, Everman JL, MacLeod HJ, Lee JW, Mason RJ, Matthay MA, Sheldon RT, Peters MC, Nocka KH, Fahy JV, …
• Metabolic consequences of obesity as an "outside in" mechanism of disease severity in asthma.
  The European respiratory journal 2016 Peters MC, Fahy JV
• Alternative splicing of interleukin-33 and type 2 inflammation in asthma.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Gordon ED, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff PG, Ansel KM, Nocka K, Seibold MA, …
• Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma.
  American journal of respiratory and critical care medicine 2014 Kerr SC, Carrington SD, Oscarson S, Gallagher ME, Solon M, Yuan S, Ahn JN, Dougherty RH, Finkbeiner WE, Peters MC, Fahy JV
• Type 2 immune responses in obese individuals with asthma.
  American journal of respiratory and critical care medicine 2013 Peters MC, Fahy JV
• New-onset asthma among soldiers serving in Iraq and Afghanistan.
  Allergy and asthma proceedings 2010 Szema AM, Peters MC, Weissinger KM, Gagliano CA, Chen JJ
• GABAB receptors on central terminals of C-afferents mediate intersegmental Adelta-afferent evoked hypoalgesia.
  European journal of pain (London, England) 2005 Jones TL, Sweitzer SM, Peters MC, Wilson SP, Yeomans DC
• Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents.
  Human gene therapy 2005 Yeomans DC, Levinson SR, Peters MC, Koszowski AG, Tzabazis AZ, Gilly WF, Wilson SP
• Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol.
  Anesthesia and analgesia 2005 Wong SME, Sweitzer SM, Peters MC, Kendig JJ
• Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia.
  Pain 2004 Sweitzer SM, Peters MC, Ma JY, Kerr I, Mangadu R, Chakravarty S, Dugar S, Medicherla S, Protter AA, Yeomans DC
• Protein kinase C epsilon and gamma: involvement in formalin-induced nociception in neonatal rats.
  The Journal of pharmacology and experimental therapeutics 2004 Sweitzer SM, Wong SM, Peters MC, Mochly-Rosen D, Yeomans DC, Kendig JJ
• CD94/NKG2 expression does not inhibit cytotoxic function of lymphocytic choriomeningitis virus-specific CD8+ T cells.
  Journal of immunology (Baltimore, Md. : 1950) 2002 Miller JD, Peters M, Oran AE, Beresford GW, Harrington L, Boss JM, Altman JD