Michael McGrath, MD, PhD
Recall Faculty
Medicine
School of Medicine

The malignancy research evolved into the establishment of a global resouce for researchers in the AIDS malgnancy field, the AIDS and Cancer Specimen Resource (ACSR). The dementia program has driven the drug develpoment effort targeting pathogenic macrophages to the point where a lead drug candidate was developed by us and has been through advanced clinical testing in patients with amyotrophic lateral sclerosis (ALS). We believe that controlled regulation of macrophage activation should be useful in a variety of clinical settings once the value has been tested in patients with ALS.

• Regulation of the Innate Immune System as a Therapeutic Approach to Supporting Respiratory Function in ALS.
  Cells 2023 McGrath MS, Zhang R, Bracci PM, Azhir A, Forrest BD
• The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi's Sarcoma Tumors during Antiretroviral Therapy.
  Viruses 2022 Nolan DJ, Rose R, Zhang R, Leong A, Fogel GB, Scholte LLS, Bethony JM, Bracci P, Lamers SL, McGrath MS
• Macrophage-Targeted Sodium Chlorite (NP001) Slows Progression of Amyotrophic Lateral Sclerosis (ALS) through Regulation of Microbial Translocation.
  Biomedicines 2022 Zhang R, Bracci PM, Azhir A, Forrest BD, McGrath MS
• Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: Pre-specified and post hoc analyses.
  Muscle & nerve 2022 Miller RG, Zhang R, Bracci PM, Azhir A, Barohn R, Bedlack R, Benatar M, Berry JD, Cudkowicz M, Kasarskis EJ, Mitsumoto H, Manousakis G, Walk D, Oskarsson B, Shefner J, McGrath MS
• The Role of Bacteria in KSHV Infection and KSHV-Induced Cancers.
  Cancers 2021 Markazi A, Meng W, Bracci PM, McGrath MS, Gao SJ
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances Kaposi's Sarcoma Herpesvirus-Induced Cell Proliferation and Cellular Transformation through both Lipopolysaccharide and Flagellin.
  mBio 2020 Markazi A, Bracci PM, McGrath M, Gao SJ
• Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency.
  Frontiers in neurology 2019 Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL
• Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature.
  International journal of cancer 2019 Maguire A, Chen X, Wisner L, Malasi S, Ramsower C, Kendrick S, Barrett MT, Glinsmann-Gibson B, McGrath M, Rimsza LM
• Emerging Patterns in HIV-1 gp120 Variable Domains in Anatomical Tissues in the Absence of a Plasma Viral Load.
  AIDS research and human retroviruses 2019 Lamers SL, Fogel GB, Nolan DJ, Barbier AE, Rose R, Singer EJ, Gonzalez-Perez MP, McGrath MS
• Methylglyoxal-bis-guanylhydrazone inhibits osteopontin expression and differentiation in cultured human monocytes.
  PloS one 2018 Jin X, Xu H, McGrath MS
• The Spleen Is an HIV-1 Sanctuary During Combined Antiretroviral Therapy.
  AIDS research and human retroviruses 2017 Nolan DJ, Rose R, Rodriguez PH, Salemi M, Singer EJ, Lamers SL, McGrath MS
• Brain-specific HIV Nef identified in multiple patients with neurological disease.
  Journal of neurovirology 2017 Lamers SL, Fogel GB, Liu ES, Barbier AE, Rodriguez CW, Singer EJ, Nolan DJ, Rose R, McGrath MS
• Eradication of HIV from Tissue Reservoirs: Challenges for the Cure.
  AIDS research and human retroviruses 2017 Rose R, Nolan DJ, Maidji E, Stoddart CA, Singer EJ, Lamers SL, McGrath MS
• Single Genome Sequencing of Expressed and Proviral HIV-1 Envelope Glycoprotein 120 (gp120) and nef Genes.
  Bio-protocol 2017 Nolan DJ, Lamers SL, Rose R, Dollar JJ, Salemi M, McGrath MS
• An oral form of methylglyoxal-bis-guanylhydrazone reduces monocyte activation and traffic to the dorsal root ganglia in a primate model of HIV-peripheral neuropathy.
  Journal of neurovirology 2017 Lakritz JR, Yalamanchili S, Polydefkis MJ, Miller AD, McGrath MS, Williams KC, Burdo TH
• Direct Targeting of Macrophages With Methylglyoxal-Bis-Guanylhydrazone Decreases SIV-Associated Cardiovascular Inflammation and Pathology.
  Journal of acquired immune deficiency syndromes (1999) 2017 Walker JA, Miller AD, Burdo TH, McGrath MS, Williams KC
• Predicted coreceptor usage at end-stage HIV disease in tissues derived from subjects on antiretroviral therapy with an undetectable plasma viral load.
  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Lamers SL, Fogel GB, Liu ES, Nolan DJ, Salemi M, Barbier AE, Rose R, Singer EJ, McGrath MS
• Corrigendum to the inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach [Nucl Med Biol 43 (2016) 215-225].
  Nuclear medicine and biology 2016 Cope FO, Abbruzzese B, Sanders J, Metz W, Sturms K, Ralph D, Blue M, Zhang J, Bracci P, Bshara W, Behr S, Maurer T, Williams K, Walker J, Beverly A, Blay B, Damughatla A, Larsen M, Mountain C, Neylon …
• HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads.
  Journal of virology 2016 Lamers SL, Rose R, Maidji E, Agsalda-Garcia M, Nolan DJ, Fogel GB, Salemi M, Garcia DL, Bracci P, Yong W, Commins D, Said J, Khanlou N, Hinkin CH, Sueiras MV, Mathisen G, Donovan S, Shiramizu B, …
• HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer.
  Journal of virology 2016 Rose R, Lamers SL, Nolan DJ, Maidji E, Faria NR, Pybus OG, Dollar JJ, Maruniak SA, McAvoy AC, Salemi M, Stoddart CA, Singer EJ, McGrath MS
• HIV-1 Evolutionary Patterns Associated with Metastatic Kaposi's Sarcoma during AIDS.
  Sarcoma 2016 Lamers SL, Rose R, Nolan DJ, Fogel GB, Barbier AE, Salemi M, McGrath MS
• On the Physicochemical and Structural Modifications Associated with HIV-1 Subtype B Tropism Transition.
  AIDS research and human retroviruses 2016 Lamers SL, Fogel GB, Liu ES, Salemi M, McGrath MS
• The inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach.
  Nuclear medicine and biology 2015 Cope FO, Abbruzzese B, Sanders J, Metz W, Sturms K, Ralph D, Blue M, Zhang J, Bracci P, Bshara W, Behr S, Maurer T, Williams K, Walker J, Beverly A, Blay B, Damughatla A, Larsen M, Mountain C, Neylon …
• The meningeal lymphatic system: a route for HIV brain migration?
  Journal of neurovirology 2015 Lamers SL, Rose R, Ndhlovu LC, Nolan DJ, Salemi M, Maidji E, Stoddart CA, McGrath MS
• Identification of dual-tropic HIV-1 using evolved neural networks.
  Bio Systems 2015 Fogel GB, Lamers SL, Liu ES, Salemi M, McGrath MS
• Inhibition of HIV Expression and Integration in Macrophages by Methylglyoxal-Bis-Guanylhydrazone.
  Journal of virology 2015 Jin X, McGrath MS, Xu H
• Tracking the Emergence of Host-Specific Simian Immunodeficiency Virus env and nef Populations Reveals nef Early Adaptation and Convergent Evolution in Brain of Naturally Progressing Rhesus Macaques.
  Journal of virology 2015 Lamers SL, Nolan DJ, Rife BD, Fogel GB, McGrath MS, Burdo TH, Autissier P, Williams KC, Goodenow MM, Salemi M
• Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS.
  Neurology(R) neuroimmunology & neuroinflammation 2015 Miller RG, Block G, Katz JS, Barohn RJ, Gopalakrishnan V, Cudkowicz M, Zhang JR, McGrath MS, Ludington E, Appel SH, Azhir A, Phase 2 Trial NP001 Investigators
• The effect of triple vs. double nonopioid therapy on postoperative pain and functional outcome after abdominal hysterectomy: a randomised double-blind control trial.
  European journal of anaesthesiology 2015 Gilron I, Tu D, Dumerton-Shore D, Duggan S, Rooney R, McGrath M, Orr E
• Factors related to HIV-associated neurocognitive impairment differ with age.
  Journal of neurovirology 2014 Fogel GB, Lamers SL, Levine AJ, Valdes-Sueiras M, McGrath MS, Shapshak P, Singer EJ
• NP001 regulation of macrophage activation markers in ALS: a phase I clinical and biomarker study.
  Amyotrophic lateral sclerosis & frontotemporal degeneration 2014 Miller RG, Zhang R, Block G, Katz J, Barohn R, Kasarskis E, Forshew D, Gopalakrishnan V, McGrath MS
• HIV-associated neuropathogenesis: a systems biology perspective for modeling and therapy.
  Bio Systems 2014 Lamers SL, Fogel GB, Nolan DJ, McGrath MS, Salemi M
• Transcriptional profiles of peripheral blood leukocytes identify patients with cholangiocarcinoma and predict outcome.
  Asian Pacific journal of cancer prevention : APJCP 2014 Subimerb C, Wongkham C, Khuntikeo N, Leelayuwat C, McGrath MS, Wongkham S
• Mechanisms, models and biomarkers in amyotrophic lateral sclerosis.
  Amyotrophic lateral sclerosis & frontotemporal degeneration 2013 Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL, Rutkove SB, Shaw PJ, Shefner J, Fischbeck KH
• Systemic immune system alterations in early stages of Alzheimer's disease.
  Journal of neuroimmunology 2013 Zhang R, Miller RG, Madison C, Jin X, Honrada R, Harris W, Katz J, Forshew DA, McGrath MS
• HIV-1 Nef in macrophage-mediated disease pathogenesis.
  International reviews of immunology 2012 Lamers SL, Fogel GB, Singer EJ, Salemi M, Nolan DJ, Huysentruyt LC, McGrath MS
• Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.
  Annals of surgical oncology 2012 Mukhtar RA, Moore AP, Tandon VJ, Nseyo O, Twomey P, Adisa CA, Eleweke N, Au A, Baehner FL, Moore DH, McGrath MS, Olopade OI, Gray JW, Campbell MJ, Esserman LJ
• HIV-1 nef protein structures associated with brain infection and dementia pathogenesis.
  PloS one 2011 Lamers SL, Poon AF, McGrath MS
• The AIDS and Cancer Specimen Resource.
  Methods in molecular biology (Clifton, N.J.) 2011 Ayers LW, Silver S, Orenstein JM, McGrath MS, Garcia DL
• HIV-1 nef protein visits B-cells via macrophage nanotubes: a mechanism for AIDS-related lymphoma pathogenesis?
  Current HIV research 2010 Lamers SL, Fogel GB, Huysentruyt LC, McGrath MS
• HIV-1 phylogenetic analysis shows HIV-1 transits through the meninges to brain and peripheral tissues.
  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2010 Lamers SL, Gray RR, Salemi M, Huysentruyt LC, McGrath MS
• Gene expression profiling in peripheral blood mononuclear cells from patients with sporadic amyotrophic lateral sclerosis (sALS).
  Journal of neuroimmunology 2010 Zhang R, Hadlock KG, Do H, Yu S, Honrada R, Champion S, Forshew D, Madison C, Katz J, Miller RG, McGrath MS
• Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.
  Breast cancer research and treatment 2010 Campbell MJ, Tonlaar NY, Garwood ER, Huo D, Moore DH, Khramtsov AI, Au A, Baehner F, Chen Y, Malaka DO, Lin A, Adeyanju OO, Li S, Gong C, McGrath M, Olopade OI, Esserman LJ
• Circulating CD14(+) CD16(+) monocyte levels predict tissue invasive character of cholangiocarcinoma.
  Clinical and experimental immunology 2010 Subimerb C, Pinlaor S, Lulitanond V, Khuntikeo N, Okada S, McGrath MS, Wongkham S
• Tissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma.
  Molecular medicine reports 2010 Subimerb C, Pinlaor S, Khuntikeo N, Leelayuwat C, Morris A, McGrath MS, Wongkham S
• HIV-miR-H1 evolvability during HIV pathogenesis.
  Bio Systems 2010 Lamers SL, Fogel GB, McGrath MS
• Human immunodeficiency virus-1 evolutionary patterns associated with pathogenic processes in the brain.
  Journal of neurovirology 2010 Lamers SL, Salemi M, Galligan DC, Morris A, Gray R, Fogel G, Zhao L, McGrath MS
• The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma.
  Journal of leukocyte biology 2009 Huysentruyt LC, McGrath MS
• Distinct patterns of HIV-1 evolution within metastatic tissues in patients with non-Hodgkins lymphoma.
  PloS one 2009 Salemi M, Lamers SL, Huysentruyt LC, Galligan D, Gray RR, Morris A, McGrath MS
• Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage.
  Journal of leukocyte biology 2009 Kim WK, Sun Y, Do H, Autissier P, Halpern EF, Piatak M, Lifson JD, Burdo TH, McGrath MS, Williams K
• High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS.
  Science in China. Series C, Life sciences 2009 Zhao L, Galligan DC, Lamers SL, Yu S, Shagrun L, Salemi M, McGrath MS
• [Analysis of genetic diversity and biological functional site of HIV-1 gp120 from a patient with AIDS dementia complex].
  Bing du xue bao = Chinese journal of virology 2009 Yan YF, Zhao L, Wang ZY, McGrath MS, Hou XY, Zheng XM, Song YY, Wen HL, Wang GT, Xu HZ
• Extensive HIV-1 intra-host recombination is common in tissues with abnormal histopathology.
  PloS one 2009 Lamers SL, Salemi M, Galligan DC, de Oliveira T, Fogel GB, Granier SC, Zhao L, Brown JN, Morris A, Masliah E, McGrath MS
• Does functional improvement following TKA correlate to increased sports activity?
  The Iowa orthopaedic journal 2009 Marker DR, Mont MA, Seyler TM, McGrath MS, Kolisek FR, Bonutti PM
• Posterior-stabilized versus posterior cruciate ligament-retaining total knee arthroplasty.
  The Iowa orthopaedic journal 2009 Kolisek FR, McGrath MS, Marker DR, Jessup N, Seyler TM, Mont MA, Lowry Barnes C
• Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS).
  Journal of neuroimmunology 2008 Zhang R, Miller RG, Gascon R, Champion S, Katz J, Lancero M, Narvaez A, Honrada R, Ruvalcaba D, McGrath MS
• Prediction of R5, X4, and R5X4 HIV-1 coreceptor usage with evolved neural networks.
  IEEE/ACM transactions on computational biology and bioinformatics 2008 Lamers SL, Salemi M, McGrath MS, Fogel GB
• The AIDS and Cancer Specimen Resource: role in HIV/AIDS scientific discovery.
  Infectious agents and cancer 2007 Ayers LW, Silver S, McGrath MS, Orenstein JM
• MCP-1 chemokine receptor CCR2 is decreased on circulating monocytes in sporadic amyotrophic lateral sclerosis (sALS).
  Journal of neuroimmunology 2006 Zhang R, Gascon R, Miller RG, Gelinas DF, Mass J, Lancero M, Narvaez A, McGrath MS
• Phylodynamic analysis of human immunodeficiency virus type 1 in distinct brain compartments provides a model for the neuropathogenesis of AIDS.
  Journal of virology 2005 Salemi M, Lamers SL, Yu S, de Oliveira T, Fitch WM, McGrath MS
• A single-centre prospective study of clinical and haemostatic risk factors for venous thromboembolism following lower limb arthroplasty.
  British journal of haematology 2005 Joseph JE, Low J, Courtenay B, Neil MJ, McGrath M, Ma D
• Evidence for systemic immune system alterations in sporadic amyotrophic lateral sclerosis (sALS).
  Journal of neuroimmunology 2004 Zhang R, Gascon R, Miller RG, Gelinas DF, Mass J, Hadlock K, Jin X, Reis J, Narvaez A, McGrath MS
• Differential effects on innate versus adaptive immune responses by WF10.
  Cellular immunology 2004 Giese T, McGrath MS, Stumm S, Schempp H, Elstner E, Meuer SC
• Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load.
  Blood 2004 Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM
• HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression.
  Journal of acquired immune deficiency syndromes (1999) 2003 Mack KD, Jin X, Yu S, Wei R, Kapp L, Green C, Herndier B, Abbey NW, Elbaggari A, Liu Y, McGrath MS
• Injection of human primary effusion lymphoma cells or associated macrophages into severe combined immunodeficient mice causes murine lymphomas.
  Cancer research 2002 Zenger E, Abbey NW, Weinstein MD, Kapp L, Reis J, Gofman I, Millward C, Gascon R, Elbaggari A, Herndier BG, McGrath MS
• Increased HLA-DR expression on peripheral blood monocytes in subsets of subjects with primary HIV infection is associated with elevated CD4 T-cell apoptosis and CD4 T-cell depletion.
  Journal of acquired immune deficiency syndromes (1999) 2002 Gascon RL, Narváez AB, Zhang R, Kahn JO, Hecht FM, Herndier BG, McGrath MS
• Development of WF10, a novel macrophage-regulating agent.
  Current opinion in investigational drugs (London, England : 2000) 2002 McGrath MS, Kahn JO, Herndier BG
• Comparative genomic analyses of primary effusion lymphoma.
  Archives of pathology & laboratory medicine 2000 Mullaney BP, Ng VL, Herndier BG, McGrath MS, Pallavicini MG
• Case-control study of non-Hodgkin's lymphoma among women and heterosexual men in the San Francisco Bay Area, California.
  American journal of epidemiology 1999 Holly EA, Lele C, Bracci PM, McGrath MS
• Balanced macrophage activation hypothesis: a biological model for development of drugs targeted at macrophage functional states.
  Pathobiology : journal of immunopathology, molecular and cellular biology 1999 McGrath MS, Kodelja V
• Effect of WF10 (TCDO) on antigen presentation.
  Transplantation proceedings 1998 McGrath MS, Benike C, Kuehne FW, Engleman E
• The immunology of AIDS-associated lymphomas.
  Immunological reviews 1998 Ng VL, McGrath MS
• A novel method for DEAE-dextran mediated transfection of adherent primary cultured human macrophages.
  Journal of immunological methods 1998 Mack KD, Wei R, Elbagarri A, Abbey N, McGrath MS
• Neutralizing human monoclonal antibodies to conformational epitopes of human T-cell lymphotropic virus type 1 and 2 gp46.
  Journal of virology 1997 Hadlock KG, Rowe J, Perkins S, Bradshaw P, Song GY, Cheng C, Yang J, Gascon R, Halmos J, Rehman SM, McGrath MS, Foung SK
• Unique monocyte subset in patients with AIDS dementia.
  Lancet (London, England) 1997 Pulliam L, Gascon R, Stubblebine M, McGuire D, McGrath MS
• VH gene use by HIV type 1-associated lymphoproliferations.
  AIDS research and human retroviruses 1997 Ng VL, Hurt MH, Herndier BG, Fry KE, McGrath MS
• Evidence for early B-cell activation preceding the development of Epstein-Barr virus-negative acquired immunodeficiency syndrome-related lymphoma.
  Blood 1996 Przybylski GK, Goldman J, Ng VL, McGrath MS, Herndier BG, Schenkein DP, Monroe JG, Silberstein LE
• Monokine products as predictors of AIDS dementia.
  AIDS (London, England) 1996 Pulliam L, Clarke JA, McGrath MS, Moore D, McGuire D
• The natural history and molecular heterogeneity of HIV-associated primary malignant lymphomatous effusions.
  Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996 Komanduri KV, Luce JA, McGrath MS, Herndier BG, Ng VL
• T-cells and macrophages in HIV disease.
  Clinical reviews in allergy & immunology 1996 McGrath MS
• VH gene use by CD5+ AIDS-associated B-cell lymphoproliferations.
  Annals of the New York Academy of Sciences 1995 Ng VL, Hurt MH, Herndier BG, McGrath MS
• Identification of a clonal form of HIV in early Kaposi's sarcoma: evidence for a novel model of oncogenesis, "sequential neoplasia".
  Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995 McGrath MS, Shiramizu BT, Herndier BG
• Influence of molecular characteristics on clinical outcome in human immunodeficiency virus-associated non-Hodgkin's lymphoma: identification of a subgroup with favorable clinical outcome.
  Blood 1995 Kaplan LD, Shiramizu B, Herndier B, Hahn J, Meeker TC, Ng V, Volberding PA, McGrath MS
• Cytokine expression in large cell lymphoma associated with acquired immunodeficiency syndrome.
  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995 Marsh JW, Herndier B, Tsuzuki A, Ng VL, Shiramizu B, Abbey N, McGrath MS
• Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads.
  The Journal of biological chemistry 1995 Rando RF, Ojwang J, Elbaggari A, Reyes GR, Tinder R, McGrath MS, Hogan ME
• HIV infection of monocyte-derived macrophages in vitro reduces phagocytosis of Candida albicans.
  Journal of leukocyte biology 1994 Crowe SM, Vardaxis NJ, Kent SJ, Maerz AL, Hewish MJ, McGrath MS, Mills J
• Inter-VH-gene-family shared idiotype on acquired immunodeficiency syndrome-associated lymphomas.
  Blood 1994 Hurt M, Herndier B, Ng V, McGrath MS
• Pathogenesis of AIDS lymphomas.
  AIDS (London, England) 1994 Herndier BG, Kaplan LD, McGrath MS
• Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine.
  Journal of acquired immune deficiency syndromes 1994 Ojwang J, Elbaggari A, Marshall HB, Jayaraman K, McGrath MS, Rando RF
• Identification of a common clonal human immunodeficiency virus integration site in human immunodeficiency virus-associated lymphomas.
  Cancer research 1994 Shiramizu B, Herndier BG, McGrath MS
• Investigation of HIV-infected macrophage neurotoxin production from patients with AIDS dementia.
  Advances in neuroimmunology 1994 Pulliam L, Clarke JA, McGuire D, McGrath MS
• Human immunodeficiency virus-infected monocyte-derived macrophages express surface gp120 and fuse with CD4 lymphoid cells in vitro: a possible mechanism of T lymphocyte depletion in vivo.
  Clinical immunology and immunopathology 1992 Crowe SM, Mills J, Elbeik T, Lifson JD, Kosek J, Marshall JA, Engleman EG, McGrath MS
• Effects of dimethyl prostaglandin A1 on herpes simplex virus and human immunodeficiency virus replication.
  Antimicrobial agents and chemotherapy 1992 Hughes-Fulford M, McGrath MS, Hanks D, Erickson S, Pulliam L
• Large-cell "mixed-phenotype" lymphoma in AIDS. Identification of a CD5-expressing subset of B-cell non-Hodgkin's lymphoma.
  Annals of the New York Academy of Sciences 1992 Mercolino TJ, Herndier B, Nolan TJ, McGrath MS
• Acquired immunodeficiency syndrome-associated T-cell lymphoma: evidence for human immunodeficiency virus type 1-associated T-cell transformation.
  Blood 1992 Herndier BG, Shiramizu BT, Jewett NE, Aldape KD, Reyes GR, McGrath MS
• AIDS associated non-Hodgkin's lymphomas represent a broad spectrum of monoclonal and polyclonal lymphoproliferative processes.
  Current topics in microbiology and immunology 1992 Herndier BG, Shiramizu BT, McGrath MS
• Purified trichosanthin (GLQ223) exacerbation of indirect HIV-associated neurotoxicity in vitro.
  AIDS (London, England) 1991 Pulliam L, Herndier BG, McGrath MS
• Molecular pathogenesis of AIDS-associated non-Hodgkin's lymphoma.
  Hematology/oncology clinics of North America 1991 Shiramizu B, McGrath MS
• Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains.
  The Journal of clinical investigation 1991 Pulliam L, Herndier BG, Tang NM, McGrath MS
• AIDS-associated polyclonal lymphoma: identification of a new HIV-associated disease process.
  Journal of acquired immune deficiency syndromes 1991 McGrath MS, Shiramizu B, Meeker TC, Kaplan LD, Herndier B
• Mediators of fusion between HIV-infected macrophages and lymphoid cells.
  Advances in experimental medicine and biology 1991 Crowe S, Mills J, McGrath MS
• Effects of GLQ223 on HIV replication in human monocyte/macrophages chronically infected in vitro with HIV.
  AIDS research and human retroviruses 1990 McGrath MS, Santulli S, Gaston I
• Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells.
  AIDS research and human retroviruses 1990 Crowe SM, Mills J, Kirihara J, Boothman J, Marshall JA, McGrath MS
• HTLV-I/II infection in women with acute pelvic inflammatory disease.
  JAMA 1990 Safrin S, Ng VL, McGrath MS, Dattel BJ, Hauer L, Sweet RL
• Compound Q.
  Nature 1990 McGrath MS, Lifson JD
• Anti-idiotypic antisera raised against monoclonal antibody specific for a p24 gag region epitope detects a common interspecies idiotype associated with anti-HIV responses.
  Viral immunology 1990 Morrow WJ, Gaston I, Anderson T, Haigwood N, McGrath MS, Rosen J, Steimer KS
• The clinical significance of human immunodeficiency virus type 1-associated paraproteins.
  Blood 1989 Ng VL, Chen KH, Hwang KM, Khayam-Bashi H, McGrath MS
• Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus.
  Journal of medical virology 1989 Crowe SM, McGrath MS, Elbeik T, Kirihara J, Mills J
• IgM secreted by human T lymphoma virus-I-infected and transformed human B cell clones recognize a 66-kilodalton host-encoded protein.
  Journal of immunology (Baltimore, Md. : 1950) 1989 Ng VL, Rainer C, Oliver MR, Marsh J, Wood P, Reyes GR, McGrath MS
• Reliable confirmation of antibodies to human immunodeficiency virus type 1 (HIV-1) with an enzyme-linked immunoassay using recombinant antigens derived from the HIV-1 gag, pol, and env genes.
  Journal of clinical microbiology 1989 Ng VL, Chiang CS, Debouck C, McGrath MS, Grove TH, Mills J
• GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage.
  Proceedings of the National Academy of Sciences of the United States of America 1989 McGrath MS, Hwang KM, Caldwell SE, Gaston I, Luk KC, Wu P, Ng VL, Crowe S, Daniels J, Marsh J
• Human retrovirus-associated malignancy.
  Cancer treatment and research 1989 McGrath MS, Ng VL
• Zidovudine-induced fever.
  Journal of acquired immune deficiency syndromes 1989 Jacobson MA, McGrath MS, Joseph P, Molaghan JB, Tadepalli S, Quinn R
• Release of interleukin 1 inhibitory activity (contra-IL-1) by human monocyte-derived macrophages infected with human immunodeficiency virus in vitro and in vivo.
  The Journal of clinical investigation 1988 Locksley RM, Crowe S, Sadick MD, Heinzel FP, Gardner KD, McGrath MS, Mills J
• Lymphoma in an HIV-positive man after disappearance of a paraprotein.
  The New England journal of medicine 1988 Ng VL, Jacobson MA, Khayam-Bashi H, McGrath MS
• High titer anti-HIV antibody reactivity associated with a paraprotein spike in a homosexual male with AIDS related complex.
  Blood 1988 Ng VL, Hwang KM, Reyes GR, Kaplan LD, Khayam-Bashi H, Hadley WK, McGrath MS
• A subset of T cell receptors associated with L3T4 molecules mediates C6VL leukemia cell binding of its cognate retrovirus.
  Cell 1987 O'Neill HC, McGrath MS, Allison JP, Weissman IL
• Molecules recognized by anti-idiotypic monoclonal antibodies to the B cell lymphoma, BCL1.
  The Journal of molecular and cellular immunology : JMCI 1987 Tamura GS, McGrath MS, Weissman IL
• Quantitative immunocytofluorographic analysis of CD4 surface antigen expression and HIV infection of human peripheral blood monocyte/macrophages.
  AIDS research and human retroviruses 1987 Crowe S, Mills J, McGrath MS
• Receptor mediated leukemogenesis: murine leukemia virus interacts with BCL1 lymphoma cell surface IgM.
  The Journal of molecular and cellular immunology : JMCI 1987 McGrath MS, Tamura G, Weissman IL
• AIDS-related benign lymphadenopathy and malignant lymphoma: clinical aspects and virologic interactions.
  AIDS research 1986 Abrams DI, Kaplan LD, McGrath MS, Volberding PA
• AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen.
  Science (New York, N.Y.) 1986 Lifson JD, Reyes GR, McGrath MS, Stein BS, Engleman EG
• Lymphocyte and lymphoma receptors utilized in differentiation, in homing, and in lymphomagenesis.
  Haematology and blood transfusion 1985 Weissman IL, McGrath MS, Reichert RA, Gallatin WM, Ezine S, Fink P, Butcher EC, Marian J, O'Neill HC
• Isolation of molecules recognized by monoclonal antibodies and antisera: the solid phase immunoisolation technique.
  Analytical biochemistry 1984 Tamura GS, Dailey MO, Gallatin WM, McGrath MS, Weissman IL, Pillemer EA
• Retrovirus lymphomagenesis: relationship of normal immune receptors to malignant cell proliferation.
  Current topics in microbiology and immunology 1982 Weissman IL, McGrath MS
• Normal and neoplastic lymphocyte maturation.
  Journal of supramolecular structure and cellular biochemistry 1981 Weissman IL, McGrath MS, Pillemer E, Hollander N, Rouse RV, Jerabek L, Stevens SK, Scollay RG, Butcher EC
• Receptor mediated murine leukemogenesis: monoclonal antibody induced lymphoma cell growth arrest.
  Haematology and blood transfusion 1981 McGrath MS, Jerabek L, Pillemer E, Steinberg RA, Weissman IL
• Murine leukaemogenesis: monoclonal antibodies to T-cell determinants arrest T-lymphoma cell proliferation.
  Nature 1980 McGrath MS, Pillemer E, Weissman IL
• T-lymphoma retroviral receptors and control of T-lymphoma cell proliferation.
  Cold Spring Harbor symposia on quantitative biology 1980 McGrath MS, Pillemer E, Kooistra DA, Jacobs S, Jerabek L, Weissman IL
• The role of MuLV receptors on T-lymphoma cells in lymphoma cell proliferation.
  Contemporary topics in immunobiology 1980 McGrath MS, Pillemer E, Kooistra D, Weissman IL
• AKR leukemogenesis: identification and biological significance of thymic lymphoma receptors for AKR retroviruses.
  Cell 1979 McGrath MS, Weissman IL
• Specificity of cell surface virus receptors on radiation leukemia virus and radiation-induced thymic lymphomas.
  Journal of virology 1978 McGrath MS, Decléve A, Lieberman M, Kaplan HS, Weissman IL