Michael Lee, MD
Assistant Professor
Medicine
School of Medicine
Education & Training
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- Pulmonary Sciences and Critical Care Medicine Fellowship University of Colorado 06/2020
- Internal Medicine Chief Resident New York University 06/2017
- Internal Medicine Residency New York University 06/2016
- MD Medicine New York University 05/2013
Grants and Projects
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- The contribution of hypoxia inducible factor-1-dependent glycolysis in lung interstitial macrophages to the pathobiology of schistosomiasis-induced pulmonary hypertension., NIH/NHLBI, 2023-2028
- The pathobiological role of dysregulated pulmonary vascular metabolism in systemic sclerosis-associated pulmonary arterial hypertension, U.S. Department of Defense, 2022-2025
- Transpulmonary Metabolomics in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension, Fulbright U.S. Scholar Program, 2022-2023
- Transpulmonary metabolomic gradients during exercise in systemic sclerosis-associated pulmonary hypertension, The CHEST Foundation (American College of Chest Physicians), 2021-2022
- Schistosomiasis-Associated Pulmonary Arterial Hypertension in Ethiopia and Zambia, UCSF, Division of Pulmonary and Critical Care Medicine, 2021-2022
- The Role of Smooth Muscle Cell Fatty Acid Oxidation in the Pathogenesis of Pulmonary Hypertension, NIH, 2020-2021
- The role of fatty acid oxidation in the pathogenesis of pulmonary hypertension, NIH, 2018-2020
- Pathogenetic role of endothelial cell fatty acid oxidation in pulmonary hypertension, University of Colorado, Division of Pulmonary Sciences and Critical Care Medicine, 2018-2020
Publications (34)
Top publication keywords:
Scleroderma, SystemicHeart VentriclesKidney CalculiSchistosoma mansoniPulmonary EosinophiliaMarijuana SmokingLung InjurySchistosomiasisAdenocarcinoma, MucinousCystinuriaMolecular MimicryVapingAirway ObstructionHypertension, PulmonaryPulmonary Artery
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Pulse Fiction: The SpO2-SaO2 Gap in Methemoglobinemia.
Annals of the American Thoracic Society 2024 Boctor D, Garudadri S, Donzelli G, Lee MH -
Classical dendritic cells contribute to hypoxia-induced pulmonary hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mickael C, Sanders LA, Lee MH, Kumar R, Fonseca-Balladares D, Gandjeva A, Cautivo-Reyes K, Kassa B, Kumar S, Irwin D, Swindle D, Phang T, Stearman RS, Molofsky AB, McKee AS, Stenmark KR, Graham BB, … -
Intrapulmonary T Cells Are Sufficient for Schistosoma-Induced Pulmonary Hypertension.
International journal of molecular sciences 2024 Fonseca Balladares DC, Kassa B, Mickael C, Kumar R, Nolan K, Menezes TCF, Lee MH, Lau-Xiao AM, Molofsky AB, Wells E, Graham BB -
Dyspnea Investigation in Behçet's Disease: The Role of Advanced Diagnostic Methods to Elucidate Dyspnea in Systemic Diseases.
Annals of the American Thoracic Society 2024 Menezes TFC, Lee MH, Lucena J, Sperandio PCA, Ota-Arakaki JS, Ferreira EVM, Oliveira RKF -
Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension.
Frontiers in immunology 2024 Kumar R, Kumar S, Mickael C, Fonseca Balladares D, Nolan K, Lee MH, Sanders L, Nilsson J, Molofsky AB, Tuder RM, Stenmark KR, Graham BB
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Pathogenesis of Pulmonary Arterial Hypertension. In: Allanore, Y., Varga, J., Denton, C.P., Kuwana, M., Chung, L., Shah, A.A. (eds) Scleroderma
Pathogenesis of Pulmonary Arterial Hypertension. In: Allanore, Y., Varga, J., Denton, C.P., Kuwana, M., Chung, L., Shah, A.A. (eds) Scleroderma. 2024 Ponticos M, Lee MH, Holmes AM, Tuder RM. -
Experimental Schistosoma haematobium pulmonary hypertension.
Pulmonary circulation 2024 Kassa B, Fonseca-Balladares DC, Kumar R, Lee MH, Mickael C, Sanders L, Nolan K, Graham BB -
Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome.
Bioscience reports 2023 Kumar R, Chanana N, Sharma K, Palmo T, Lee MH, Mishra A, Nolan K, Fonseca Balladares DC, Mickael C, Gupta MD, Thinlas T, Pasha Q, Graham BB -
Is pulmonary arterial hypertension associated with schistosomiasis distinct from pulmonary arterial hypertension associated with portal hypertension?
JHLT open 2023 Graham BB, Hilton JF, Lee MH, Kumar R, Balladares DF, Rahaghi FN, Estépar RSJ, Mickael C, Lima RLB, Loureiro CMC, Lucena J, Oliveira RKF, Corrêa RA -
Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension.
Clinical science (London, England : 1979) 2023 Kumar R, Lee MH, Kassa B, Fonseca Balladares DC, Mickael C, Sanders L, Andruska A, Kumar M, Spiekerkoetter E, Bandeira A, Stenmark KR, Tuder RM, Graham BB -
The COVID-19 pandemic and pulmonary arterial hypertension in Italy: adaptation, outcomes and valuable lessons learned.
The European respiratory journal 2022 Mickael C, Lee MH, Graham BB -
Exercise metabolomics in pulmonary arterial hypertension: Where pulmonary vascular metabolism meets exercise physiology.
Frontiers in physiology 2022 Lee MH, Menezes TCF, Reisz JA, Ferreira EVM, Graham BB, Oliveira RKF -
The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension.
Pulmonary circulation 2022 Gu S, Mickael C, Kumar R, Lee MH, Sanders L, Kassa B, Harral J, Williams J, Hansen KC, Stenmark KR, Tuder RM, Graham BB -
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2022 Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM -
Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform.
American journal of respiratory cell and molecular biology 2022 Mickael C, Kheyfets VO, Langouët-Astrié C, Lee MH, Sanders LA, Trentin CO, Sweatt AJ, Zamanian RT, Bull TM, Stenmark K, Graham BB, Tuder RM -
Rationale and design of a screening study to detect schistosomiasis-associated pulmonary hypertension in Ethiopia and Zambia.
Pulmonary circulation 2022 Sinkala E, Ahmed HY, Sibomana JP, Lee MH, Kassa B, Kumar R, Mazimba S, Binegdie AB, Mpisa S, Wamundila K, Graham BB, Hilton JF -
Experimental Schistosoma japonicum-induced pulmonary hypertension.
PLoS neglected tropical diseases 2022 Kassa B, Lee MH, Kumar R, Mickael C, Sanders L, Tuder RM, Mentink-Kane M, Graham BB -
Double Trouble: Airflow and Pulmonary Vascular Obstruction.
American journal of respiratory and critical care medicine 2021 Lee MH, Graham BB, Bull TM -
Pathology of Pulmonary Arterial Hypertension. In: Janes SM, ed. Encyclopedia of Respiratory Medicine
2021 Lee MH, Tuder RM. -
Two Birds with One Stone: Helping the Pulmonary Arteries and the Right Ventricle by Targeting BMPR2 Signaling.
American journal of respiratory cell and molecular biology 2021 Lee MH, Mickael C, Graham BB -
Endothelial cell PHD2-HIF1α-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2021 Kassa B, Kumar R, Mickael C, Sanders L, Vohwinkel C, Lee MH, Gu S, Poth JM, Stenmark KR, Zhao YY, Tuder RM, Graham BB -
Pulmonary Arterial Hypertension and Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Novel Association?
Chest 2021 Lee MH, Doran J, Bang TJ, Hohsfield R, Hountras P, Boddie G, Wagh MS, Badesch D, Bull TM -
A Case and Brief Review of Bilious Ascites and Abdominal Compartment Syndrome from Pancreatitis-Induced Post-Roux-En-Y Gastric Remnant Leak
Southwest J Pulm Crit Care. 2021 Martin MA, Lee MH, Neumeier A, Huie TJ. -
Arterial vascular volume changes with haemodynamics in schistosomiasis-associated pulmonary arterial hypertension.
The European respiratory journal 2021 Rahaghi FN, Hilton JF, Corrêa RA, Loureiro C, Ota-Arakaki JS, Verrastro CGY, Lee MH, Mickael C, Nardelli P, Systrom DA, Waxman AB, Washko GR, San José Estépar R, Graham BB, Oliveira RKF -
Histopathological Correlation of Acute on Chronic Eosinophilic Pneumonitis Caused by Vaporized Cannabis Oil Inhalation.
Chest 2021 Lee MH, Cool CD, Maloney JP -
Schistosomiasis Pulmonary Arterial Hypertension.
Frontiers in immunology 2020 Sibomana JP, Campeche A, Carvalho-Filho RJ, Correa RA, Duani H, Pacheco Guimaraes V, Hilton JF, Kassa B, Kumar R, Lee MH, Loureiro CMC, Mazimba S, Mickael C, Oliveira RKF, Ota-Arakaki JS, Rezende CF, … -
Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19.
ERJ open research 2020 Kumar R, Lee MH, Mickael C, Kassa B, Pasha Q, Tuder R, Graham B -
Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.
Scientific reports 2020 Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB -
The role of pulmonary arterial hypertension-targeted therapy in systemic sclerosis.
F1000Research 2019 Lee MH, Bull TM -
IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension.
American journal of respiratory cell and molecular biology 2019 Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB -
Comparing pulmonary hypertension severity between rat strains suggests right ventricle NK cells are protective.
Cardiovascular research 2019 Mickael C, Lee MH, Gu S, Graham BB -
Common genetic variants in pulmonary arterial hypertension.
The Lancet. Respiratory medicine 2018 Gu S, Kumar R, Lee MH, Mickael C, Graham BB -
Cystine growth inhibition through molecular mimicry: a new paradigm for the prevention of crystal diseases.
Current rheumatology reports 2015 Lee MH, Sahota A, Ward MD, Goldfarb DS -
Crystal growth inhibitors for the prevention of L-cystine kidney stones through molecular design.
Science (New York, N.Y.) 2010 Rimer JD, An Z, Zhu Z, Lee MH, Goldfarb DS, Wesson JA, Ward MD