Michael Evans, PhD
Professor
Radiology
School of Medicine

Mary’s College of Maryland and he obtained his PhD in Organic Chemistry from The Scripps Research Institute (CA) under the supervision of Professor Benjamin Cravatt. This was followed by a postdoctoral fellowship in Molecular Imaging from the Memorial Sloan Kettering Cancer Center in New York under the supervision of Professors Charles Sawyers and Jason Lewis. In 2013, Dr. Evans accepted a faculty position at UCSF.

Dr. Evans has published over 80 peer-reviewed articles, 40 meeting abstracts, and is a co-inventor on 13 patents pending or issued. Dr. Evans also is the principle investigator or co-PI on several human trials focused on new strategies for imaging and treating tumors with radiopharmaceuticals. He is a scientific co-founder and previously served on the scientific advisory board of ORIC Pharmaceuticals, Inc. He is a co-founder of Therapaint, Inc, Honeybear Biosciences, and Hap10, Inc. Dr. Evans is a member of the American Chemical Society, the Society of Nuclear Medicine and Molecular Imaging, and the World Molecular Imaging Society. He has been invited nationally and internationally to lecture about his research. Has been recognized with numerous honors, including a Young Investigator Award from the Prostate Cancer Foundation, a Pathway to Independence Award from the National Cancer Institute, a Research Scholar Award from the American Chemical Society, the 2023 Roger Tsien Award for excellence in chemical biology from the World Molecular Imaging Society, and he was a 2020 inductee to the Council of Distinguished Investigators in the Academy of Radiology and Biomedical Imaging Research.

Expertise: Chemical Biology, Positron emission tomography, Targeted Radioligand Therapy, Organic Chemistry, Cancer Biology,

Education and Training:

• Bachelor of Art: St. Mary’s College, St. Mary’s City, Maryland - Chemistry
• Doctor of Philosophy: The Scripps Research Institute, La Jolla, California - Organic Chemistry
• Postdoctoral Fellowship: Memorial Sloan Kettering Cancer Center, New York - Molecular Imaging

• Dosimetry Reconstruction in Radiopharmaceutical Therapy Using a Sparse Network of External ?-Sensors.
  International Journal of Radiation Oncology • Biology • Physics 2023 R. Lall, M. Evans, Y. Seo, A. Niknejad, M. Anwar
• Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo.
  Journal of the American Chemical Society 2023 Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, …
• Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects.
  ACS central science 2023 Klauser PC, Chopra S, Cao L, Bobba KN, Yu B, Seo Y, Chan E, Flavell RR, Evans MJ, Wang L
• Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from [ 18 F]FDG yield potent sensors of living bacteria in vivo.
  bioRxiv : the preprint server for biology 2023 Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, …
• Theranostic Targeting of CUB Domain-Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Chopra S, Trepka K, Sakhamuri S, Carretero-González A, Zhu J, Egusa E, Zhou J, Leung K, Zhao N, Hooshdaran N, Feng FY, Wells JA, Chou J, Evans MJ
• Preclinical evaluation of theranostic strategy using nanoplatform and transferrin to target hyperactivity of cMYC in the context of non-small cell lung cancer.
  Nuklearmedizin - NuclearMedicine 2023 S. Martin Aubert, M. Richard, D. Kereselidze, M. Evans, B. Kuhnast, E. Porcel, C. Truillet
• Elevated labile iron in castration-resistant prostate cancer is targetable with ferrous iron-activatable antiandrogen therapy.
  European journal of medicinal chemistry 2023 Gonciarz RL, Sakhamuri S, Hooshdaran N, Kumar G, Kim H, Evans MJ, Renslo AR
• Avalanche Photodiode-Based ?-Photon Scintillation Detectors for Personalized Dosimetry in Targeted Radionuclide Therapy.
  International Journal of Radiation Oncology • Biology • Physics 2022 R. Lall, K. Lee, S. Chopra, A. Niknejad, M. Evans, M. Anwar
• Personalized Lu177 Theranostic Dosimetry Using a Single Beta-Particle In Vivo Microdosimeter.
  International Journal of Radiation Oncology • Biology • Physics 2022 K. Lee, R. Lall, S. Chopra, M.M. Maharbiz, M. Evans, M. Anwar
• Impact of Radiolabeling Strategies on the Pharmacokinetics and Distribution of an Anti-PD-L1 PET Ligand.
  Molecular pharmaceutics 2022 Tran VL, Bouleau A, Nozach H, Richard M, Chevaleyre C, Dubois S, Kereselidze D, Kuhnast B, Evans MJ, Specklin S, Truillet C
• CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Zhao N, Chopra S, Trepka K, Wang YH, Sakhamuri S, Hooshdaran N, Kim H, Zhou J, Lim SA, Leung KK, Egusa EA, Zhu J, Zhang L, Foye A, Sriram R, Chan E, Seo Y, Feng FY, Small EJ, Chou J, Wells JA, …
• Defining the Magnetic Resonance Features of Renal Lesions and Their Response to Everolimus in a Transgenic Mouse Model of Tuberous Sclerosis Complex.
  Frontiers in oncology 2022 Agarwal S, Decavel-Bueff E, Wang YH, Qin H, Santos RD, Evans MJ, Sriram R
• Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors.
  The Journal of experimental medicine 2022 Jiang H, Muir RK, Gonciarz RL, Olshen AB, Yeh I, Hann BC, Zhao N, Wang YH, Behr SC, Korkola JE, Evans MJ, Collisson EA, Renslo AR
• Switchable assembly and function of antibody complexes in vivo using a small molecule.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Martinko AJ, Simonds EF, Prasad S, Ponce A, Bracken CJ, Wei J, Wang YH, Chow TL, Huang Z, Evans MJ, Wells JA, Hill ZB
• Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.
  The Journal of clinical investigation 2022 Lim SA, Zhou J, Martinko AJ, Wang YH, Filippova EV, Steri V, Wang D, Remesh SG, Liu J, Hann B, Kossiakoff AA, Evans MJ, Leung KK, Wells JA
• In Vivo Profiling with 18F-YJH08 Reveals Diverse Tissue Patterns of Antagonist/Glucocorticoid Receptor Interactions.
  Molecular pharmaceutics 2022 Kim H, Huang Y, Zhao N, Wang YH, Sakhamuri S, Chopra S, Hooshdaran N, Sriram R, Aggarwal R, Evans MJ
• Preparation of Radiolabeled Antibodies for Nuclear Medicine Applications in Immuno-Oncology.
  Methods in molecular biology (Clifton, N.J.) 2022 Wei J, Oh DY, Evans MJ
• Optimizing Immuno-PET Imaging of Tumor PD-L1 Expression: Pharmacokinetic, Biodistribution, and Dosimetric Comparisons of 89Zr-Labeled Anti-PD-L1 Antibody Formats.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2021 Bouleau A, Nozach H, Dubois S, Kereselidze D, Chevaleyre C, Wang CI, Evans MJ, Lebon V, Maillère B, Truillet C
• Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen.
  ACS applied materials & interfaces 2021 Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR
• In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET.
  ACS central science 2021 Zhao N, Bardine C, Lourenço AL, Wang YH, Huang Y, Cleary SJ, Wilson DM, Oh DY, Fong L, Looney MR, Evans MJ, Craik CS
• Quantitative Tissue Pharmacokinetics and EPR Effect of AGuIX Nanoparticles: A Multimodal Imaging Study in an Orthotopic Glioblastoma Rat Model and Healthy Macaque.
  Advanced healthcare materials 2021 Tran VL, Lux F, Tournier N, Jego B, Maître X, Anisorac M, Comtat C, Jan S, Selmeczi K, Evans MJ, Tillement O, Kuhnast B, Truillet C
• Feasibility study of gallium-68 citrate PET as a bone-tropic imaging biomarker in mCRPC.
  Journal of Clinical Oncology 2021 Ivan de Kouchkovsky, Spencer Behr, Li Zhang, Adam Foye, Henry Vanbrocklin, Eric Jay Small, Felix Y Feng, Terence W. Friedlander, Patricia Li, Natalie Frey, Andy Chung, Austin Lui, Aishwarya …
• Synthesis and Screening of α-Xylosides in Human Glioblastoma Cells.
  Molecular pharmaceutics 2020 Kalita M, Villanueva-Meyer J, Ohkawa Y, Kalyanaraman C, Chen K, Mohamed E, Parker MFL, Jacobson MP, Phillips JJ, Evans MJ, Wilson DM
• Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Wang S, Li J, Hua J, Su Y, Beckford-Vera DR, Zhao W, Jayaraman M, Huynh TL, Zhao N, Wang YH, Huang Y, Qin F, Shen S, Gioeli D, Dreicer R, Sriram R, Egusa EA, Chou J, Feng FY, Aggarwal R, Evans MJ, Seo…
• Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2020 Zhao N, Huang Y, Wang YH, Muir RK, Chen YC, Wei J, Hooshdaran N, Viswanath P, Seo Y, Ruggero D, Renslo AR, Evans MJ
• The Synthesis and Structural Requirements for Measuring Glucocorticoid Receptor Expression In Vivo with (±)-11C-YJH08 PET.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2020 Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Parker MFL, Blecha JE, Drake CR, VanBrocklin HF, Garrido-Ruiz D, Jacobson MP, Aggarwal R, Behr SC, Flavell RR, Wilson DM, Seo Y, Evans MJ
• An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers.
  Molecular imaging and biology 2020 Wei J, Wang YH, Lee CY, Truillet C, Oh DY, Xu Y, Ruggero D, Flavell RR, VanBrocklin HF, Seo Y, Craik CS, Fong L, Wang CI, Evans MJ
• Understanding Response to Immunotherapy Using Standard of Care and Experimental Imaging Approaches.
  International journal of radiation oncology, biology, physics 2020 Flavell RR, Evans MJ, Villanueva-Meyer JE, Yom SS
• Arabinofuranose-derived positron-emission tomography radiotracers for detection of pathogenic microorganisms.
  Journal of labelled compounds & radiopharmaceuticals 2020 Kalita M, Parker MFL, Luu JM, Stewart MN, Blecha JE, VanBrocklin HF, Evans MJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM
• Quantitative and Qualitative Improvement of Low-Count [68Ga]Citrate and [90Y]Microspheres PET Image Reconstructions Using Block Sequential Regularized Expectation Maximization Algorithm.
  Molecular imaging and biology 2020 Seo Y, Khalighi MM, Wangerin KA, Deller TW, Wang YH, Jivan S, Kohi MP, Aggarwal R, Flavell RR, Behr SC, Evans MJ
• Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.
  Molecular & cellular proteomics : MCP 2019 Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ
• Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy.
  Molecular pharmaceutics 2019 Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR
• Abstract 550: Tumor-conditional anti-CTLA-4 uncouples anti-tumor efficacy from immunotherapy-related toxicity.
  Cancer Research 2019 Steven C. Pai, Donald M. Simons, Xiaoqing Lu, Wendy Ritacco, Michael Evans, Gillian Kingsbury, Lawrence Fong
• Enzymatically Catalyzed Radiofluorination of Biomolecules.
  Methods in molecular biology (Clifton, N.J.) 2019 Drake CR, Evans MJ, VanBrocklin HF
• Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
  The Journal of clinical investigation 2018 Pai CS, Simons DM, Lu X, Evans M, Wei J, Wang YH, Chen M, Huang J, Park C, Chang A, Wang J, Westmoreland S, Beam C, Banach D, Bowley D, Dong F, Seagal J, Ritacco W, Richardson PL, Mitra S, Lynch G, …
• Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR.
  JCI insight 2018 Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ
• A Preclinical Assessment of 89Zr-atezolizumab Identifies a Requirement for Carrier Added Formulations Not Observed with 89Zr-C4.
  Bioconjugate chemistry 2018 Moroz A, Lee CY, Wang YH, Hsiao JC, Sevillano N, Truillet C, Craik CS, Fong L, Wang CI, Evans MJ
• A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Henry KE, Dacek MM, Dilling TR, Caen JD, Fox IL, Evans MJ, Lewis JS
• AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.
  The British journal of radiology 2018 Lux F, Tran VL, Thomas E, Dufort S, Rossetti F, Martini M, Truillet C, Doussineau T, Bort G, Denat F, Boschetti F, Angelovski G, Detappe A, Crémillieux Y, Mignet N, Doan BT, Larrat B, Meriaux S, …
• Impact of long-term androgen deprivation therapy on PSMA ligand PET/CT in patients with castration-sensitive prostate cancer.
  European journal of nuclear medicine and molecular imaging 2018 Afshar-Oromieh A, Debus N, Uhrig M, Hope TA, Evans MJ, Holland-Letz T, Giesel FL, Kopka K, Hadaschik B, Kratochwil C, Haberkorn U
• Abstract 3694: Measuring oncogene signaling with transferrin-based PET: From bench to bedside.
  Clinical Research (Excluding Clinical Trials) 2018 Michael J. Evans, Charles Truillet, Davide Ruggero, Jason S. Lewis, Rahul Aggarwal, Spencer C. Behr
• Heterogeneous Flare in Prostate-specific Membrane Antigen Positron Emission Tomography Tracer Uptake with Initiation of Androgen Pathway Blockade in Metastatic Prostate Cancer.
  European urology oncology 2018 Aggarwal R, Wei X, Kim W, Small EJ, Ryan CJ, Carroll P, Cooperberg M, Evans MJ, Hope T
• Development of a stress response therapy targeting aggressive prostate cancer.
  Science translational medicine 2018 Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D
• PET imaging of tumor PD-L1 expression with 89Zr-labeled anti-PD-L1 antibodies.
  Nuklearmedizin 2018 C. Truillet, N. Sevillano, B. Jego, E. Jaumain, C. Craik, C.I. Wang, M. Evans
• Measuring glucocorticoid receptor expression in vivo with PET.
  Oncotarget 2018 Truillet C, Parker MFL, Huynh LT, Wei J, Jami KM, Wang YH, Shen YS, Sriram R, Wilson DM, Kurhanewicz J, Evans MJ
• Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.
  eLife 2018 Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA
• Imaging PD-L1 Expression with ImmunoPET.
  Bioconjugate chemistry 2017 Truillet C, Oh HLJ, Yeo SP, Lee CY, Huynh LT, Wei J, Parker MFL, Blakely C, Sevillano N, Wang YH, Shen YS, Olivas V, Jami KM, Moroz A, Jego B, Jaumain E, Fong L, Craik CS, Chang AJ, Bivona TG, Wang CI…
• Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen.
  ACS chemical biology 2017 de Jesus Cortez F, Nguyen P, Truillet C, Tian B, Kuchenbecker KM, Evans MJ, Webb P, Jacobson MP, Fletterick RJ, England PM
• Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade.
  Genes & development 2017 Lue HW, Podolak J, Kolahi K, Cheng L, Rao S, Garg D, Xue CH, Rantala JK, Tyner JW, Thornburg KL, Martinez-Acevedo A, Liu JJ, Amling CL, Truillet C, Louie SM, Anderson KE, Evans MJ, O'Donnell VB, …
• Noninvasive 89Zr-Transferrin PET Shows Improved Tumor Targeting Compared with 18F-FDG PET in MYC-Overexpressing Human Triple-Negative Breast Cancer.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017 Henry KE, Dilling TR, Abdel-Atti D, Edwards KJ, Evans MJ, Lewis JS
• Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer.
  Molecular cancer research : MCR 2017 Aggarwal R, Behr SC, Paris PL, Truillet C, Parker MFL, Huynh LT, Wei J, Hann B, Youngren J, Huang J, Premasekharan G, Ranatunga N, Chang E, Gao KT, Ryan CJ, Small EJ, Evans MJ
• Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development.
  Translation Control: an Adaptive Response to Oncogenic Cellular Stress 2017 Crystal S. Conn, Hao G. Nguyen, Yae Kye, John T. Cunningham, Charles Truillet, Michael Evans, Tony L. Huynh, Peter Walters, Davide Ruggero
• Imaging Hepatocellular Carcinoma With 68Ga-Citrate PET: First Clinical Experience.
  Molecular imaging 2017 Mari Aparici C, Behr SC, Seo Y, Kelley RK, Corvera C, Gao KT, Aggarwal R, Evans MJ
• Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Truillet C, Cunningham JT, Parker MFL, Huynh LT, Conn CS, Ruggero D, Lewis JS, Evans MJ
• A Feasibility Study Showing [68Ga]Citrate PET Detects Prostate Cancer.
  Molecular imaging and biology 2016 Behr SC, Aggarwal R, Seo Y, Aparici CM, Chang E, Gao KT, Tao DH, Small EJ, Evans MJ
• Synthesis and Characterization of (89)Zr-Labeled Ultrasmall Nanoparticles.
  Molecular pharmaceutics 2016 Truillet C, Thomas E, Lux F, Huynh LT, Tillement O, Evans MJ
• A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography.
  Chemical science 2016 Liu W, Truillet C, Flavell RR, Brewer TF, Evans MJ, Wilson DM, Chang CJ
• Site-Specific Radiofluorination of Biomolecules with 8-[(18)F]-Fluorooctanoic Acid Catalyzed by Lipoic Acid Ligase.
  ACS chemical biology 2016 Drake CR, Sevillano N, Truillet C, Craik CS, VanBrocklin HF, Evans MJ
• [(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography.
  Chemical communications (Cambridge, England) 2016 Carroll VN, Truillet C, Shen B, Flavell RR, Shao X, Evans MJ, VanBrocklin HF, Scott PJ, Chin FT, Wilson DM
• A Reactivity-Based [18F]FDG Probe for In Vivo Formaldehyde Imaging Using Positron Emission Tomography
  Chemical Science 2016 Liu, W.; Truillet, C.; Flavell, R.R.; Brewer, T.; Evans, M.J.; Wilson, D.M.; Chang, C.
• 11C-Ascorbic and 11C-dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography
  Chemical Communications 2016 Carroll, V.N.; Truillet, C.; Shen, B.; Flavell, R.R.; Shao, X.; Evans, M.J.; VanBrocklin, H.F.; Scott, P.H.J.; Chin, F.T.; Wilson, D.M.
• Applying ⁸⁹Zr-Transferrin To Study the Pharmacology of Inhibitors to BET Bromodomain Containing Proteins.
  Molecular pharmaceutics 2016 Doran MG, Carnazza KE, Steckler JM, Spratt DE, Truillet C, Wongvipat J, Sawyers CL, Lewis JS, Evans MJ
• Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography.
  Bioconjugate chemistry 2015 Flavell RR, Truillet C, Regan MK, Ganguly T, Blecha JE, Kurhanewicz J, VanBrocklin HF, Keshari KR, Chang CJ, Evans MJ, Wilson DM
• Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation.
  Cancer research 2015 Spratt DE, Evans MJ, Davis BJ, Doran MG, Lee MX, Shah N, Wongvipat J, Carnazza KE, Klee GG, Polkinghorn W, Tindall DJ, Lewis JS, Sawyers CL
• Anthropometric Measures at Multiple Times Throughout Life and Prostate Cancer Diagnosis, Metastasis, and Death.
  European urology 2015 Gerdtsson A, Poon JB, Thorek DL, Mucci LA, Evans MJ, Scardino P, Abrahamsson PA, Nilsson P, Manjer J, Bjartell A, Malm J, Vickers A, Freedland SJ, Lilja H, Ulmert D
• Annotating STEAP1 regulation in prostate cancer with 89Zr immuno-PET.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014 Doran MG, Watson PA, Cheal SM, Spratt DE, Wongvipat J, Steckler JM, Carrasquillo JA, Evans MJ, Lewis JS
• Cabozantinib Resolves Bone Scans in Tumor-Naïve Mice Harboring Skeletal Injuries.
  Molecular imaging 2014 Doran MG, Spratt DE, Wongvipat J, Ulmert D, Carver BS, Sawyers CL, Evans MJ
• 89Zr-MSTP2109A, A Novel Antibody Based Radiotracer to Evaluate and Guide the Clinical Translation of Antibody-Drug Conjugates Targeting STEAP1.
  International Journal of Radiation Oncology • Biology • Physics 2014 D.E. Spratt, M.G. Doran, J. Wongvipat, J.S. Lewis, M.J. Evans
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.
  Genes & development 2014 Huang CH, Lujambio A, Zuber J, Tschaharganeh DF, Doran MG, Evans MJ, Kitzing T, Zhu N, de Stanchina E, Sawyers CL, Armstrong SA, Lewis JS, Sherr CJ, Lowe SW
• Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma.
  European journal of nuclear medicine and molecular imaging 2014 Cheal SM, Punzalan B, Doran MG, Evans MJ, Osborne JR, Lewis JS, Zanzonico P, Larson SM
• Cabozantinib resolves bone scans in tumor-naïve mice harboring skeletal injuries.
  Molecular imaging 2014 Doran MG, Spratt DE, Wongvipat J, Ulmert D, Carver BS, Sawyers CL, Evans MJ
• Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.
  Inorganic chemistry 2013 Zeglis BM, Houghton JL, Evans MJ, Viola-Villegas N, Lewis JS
• Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013 Viola-Villegas NT, Rice SL, Carlin S, Wu X, Evans MJ, Sevak KK, Drobjnak M, Ragupathi G, Sawada R, Scholz WW, Livingston PO, Lewis JS
• Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging roles.
  Thrombosis and haemostasis 2013 Thorek DL, Evans MJ, Carlsson SV, Ulmert D, Lilja H
• Overcoming mutation-based resistance to antiandrogens with rational drug design.
  eLife 2013 Balbas MD, Evans MJ, Hosfield DJ, Wongvipat J, Arora VK, Watson PA, Chen Y, Greene GL, Shen Y, Sawyers CL
• Imaging of tumor vascularization using fluorescence molecular tomography to monitor arginine deiminase treatment in melanoma.
  Molecular imaging 2013 Stelter L, Evans MJ, Jungbluth AA, Longo VA, Zanzonico P, Ritter G, Bomalaski JS, Old L, Larson SM
• Imaging tumor burden in the brain with 89Zr-transferrin.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012 Evans MJ, Holland JP, Rice SL, Doran MG, Cheal SM, Campos C, Carlin SD, Mellinghoff IK, Sawyers CL, Lewis JS
• Measuring oncogenic signaling pathways in cancer with PET: an emerging paradigm from studies in castration-resistant prostate cancer.
  Cancer discovery 2012 Evans MJ
• Annotating MYC status with 89Zr-transferrin imaging.
  Nature medicine 2012 Holland JP, Evans MJ, Rice SL, Wongvipat J, Sawyers CL, Lewis JS
• Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.
  Cancer discovery 2012 Ulmert D, Evans MJ, Holland JP, Rice SL, Wongvipat J, Pettersson K, Abrahamsson PA, Scardino PT, Larson SM, Lilja H, Lewis JS, Sawyers CL
• Abstract IA22: Molecular Imaging of androgen receptor signalling in CRPC.
  Cancer Research 2012 Steven M. Larson, Joe Fox, Michael Morris, Michael Evans, Jason Lewis, John Humm, Charles L. Sawyers, Howard I. Scher
• A novel automated platform for quantifying the extent of skeletal tumour involvement in prostate cancer patients using the Bone Scan Index.
  European urology 2012 Ulmert D, Kaboteh R, Fox JJ, Savage C, Evans MJ, Lilja H, Abrahamsson PA, Björk T, Gerdtsson A, Bjartell A, Gjertsson P, Höglund P, Lomsky M, Ohlsson M, Richter J, Sadik M, Morris MJ, Scher HI, …
• Novel mechanistic insights into arginine deiminase pharmacology suggest 18F-FDG is not suitable to evaluate clinical response in melanoma.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012 Stelter L, Evans MJ, Jungbluth AA, Zanzonico P, Ritter G, Ku T, Rosenfeld E, Bomalaski JS, Old L, Larson SM
• Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Evans MJ, Smith-Jones PM, Wongvipat J, Navarro V, Kim S, Bander NH, Larson SM, Sawyers CL
• The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
  Proceedings of the National Academy of Sciences of the United States of America 2010 Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, Rajasekaran A, Liau LM, Cloughesy TF, Dikic …
• Abstract B207: Prostate specific membrane antigen is a diagnostic marker of response to allosteric androgen receptor inhibition.
  Molecular Cancer Therapeutics 2009 Michael J. Evans, Peter Smith-Jones, John Wongvipat, Steven M. Larson, Charles L. Sawyers
• Polyanionic gallium hydrides from AlB2-type precursors AeGaE (Ae = Ca, Sr, Ba; E = Si, Ge, Sn).
  Journal of the American Chemical Society 2008 Evans MJ, Holland GP, Garcia-Garcia FJ, Häussermann U
• Mechanistic and structural requirements for active site labeling of phosphoglycerate mutase by spiroepoxides.
  Molecular bioSystems 2007 Evans MJ, Morris GM, Wu J, Olson AJ, Sorensen EJ, Cravatt BF
• Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
  Nature 2007 Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, Patapoutian A
• Mechanism-based profiling of enzyme families.
  Chemical reviews 2006 Evans MJ, Cravatt BF
• Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling.
  Nature biotechnology 2005 Evans MJ, Saghatelian A, Sorensen EJ, Cravatt BF