Michael Douglas
Program Manager
Clinical Pharmacy
School of Pharmacy
michael.douglas@ucsf.edu 415-502-4025
My role is as the Program Manager for the University of California San Francisco (UCSF) Department of Clinical Pharmacy’s Research Support Program. My research spans a variety of disciplines, including clinical and social sciences, in the academic, government and industry sectors.
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I have extensive expertise in genomic laboratory medicine, evidence-based reviews of molecular-based testing, personalized medicine, and research program management. I have been working with many investigators, including Jeroen Jansen, Kathryn Phillips, and Akinyemi Oni-Orisan, in the field for over 20 years in varying organizations, including the Centers for Disease Control and Prevention’s Office of Public Health Genomics, Blue Cross Blue Shield Association’s Technical Evaluation Center and Bayer Diagnostics. Prior to managing the Research Support Program and TRANSPERS Program, I served as the Project Coordinator for the Evaluation of Genomic Applications in Practice and Prevention at the Centers for Disease Control and Prevention for eight years, where I was an integral part of developing EGAPP methodology, leading evidence-based reviews of genomic technologies, and publication of associated research, reviews, and recommendations. I have led several publications in the applications of genomics and have 33 co-authored publications in the field of genomic medicine and molecular diagnostics, with over 60 total publications across a variety of disciplines. As Program Manager, Mr. Douglas has had a leadership role in research development, program management, and publication.
He earned his Masters degree in molecular biology from SUNY – Environmental Science and Forestry and has expertise in genomic laboratory medicine, evidence-based reviews of molecular-based testing, and research program management.
He has been working in genomic medicine research for over 25 years, the last decade at UCSF, and with varying organizations, including the Centers for Disease Control and Prevention’s Office of Public Health Genomics, Blue Cross Blue Shield Association’s Technical Evaluation Center, and Bayer Diagnostics.
Education & Training
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- MS Molecular Biology SUNY-College of Environmental Science and Forestry 05/1997
- BS Plant Biotechnology SUNY-College of Environmental Science and Forestry 05/1995
Interests
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- Payer Coverage Decisions
- Health Policy
- clinical decision support
- patient-reported outcome measures
- patient generated health data
- Next-Generation Sequencing
- Polygenic Risk Score
- Molecular Testing
- Cardiovascular Disease
- big data
- consumer health informatics
- Personalized Medicine
- precision medicine
- Cancer
- Reimbursement
- Genetics/Genomics
- electronic health records (EHR)
Websites
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- @@MDouglas_MS on Twitter (twitter.com)
Grants and Projects
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- Building the Evidence Base for Appropriate and Efficient Implementation of Emerging Genomic Tests for Disease Management and Screening, NIH, 2021-2026
- Prevention of Fractures in Patients with Parkinson's Disease, NIH, 2018-2023
- , California Initiative to Advance Precision Medicine, 2019-2022
- Genomic sequencing to aid diagnosis in pediatric and prenatal practice: Examining clinical utility, ethical implications, payer coverage, and data integration in a diverse population., NIH, 2017-2022
- Coverage, Price, and Reimbursement for Multigene Tests for Cancer and Related Conditions, NIH, 2018-2021
Publications (63)
Top publication keywords:
Technology Assessment, BiomedicalPrecision MedicineGenetic TestingCarcinoma, Non-Small-Cell LungHealth ExpendituresExomeGenomicsCirculating Tumor DNAClinical Laboratory ServicesHigh-Throughput Nucleotide SequencingDirect-To-Consumer Screening and TestingInsurance CoverageInsurance, Health, ReimbursementPolicyComparative Effectiveness Research
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Clinical Validity and Utility of Circulating Tumor DNA (ctDNA) Testing in Advanced Non-small Cell Lung Cancer (aNSCLC): A Systematic Literature Review and Meta-analysis.
Molecular diagnosis & therapy 2024 Chen C, Douglas MP, Ragavan MV, Phillips KA, Jansen JP -
SLCO1B1 functional variants and statin-induced myopathy in people with recent genealogical ancestors from Africa: a population-based real-world study.
medRxiv : the preprint server for health sciences 2023 Yee SW, Haldar T, Kvale M, Yang J, Douglas MP, Oni-Orisan A -
Clinical validity and utility of circulating tumor DNA (ctDNA) testing in advanced non-small cell lung cancer (aNSCLC): a systematic literature review and meta-analysis.
medRxiv : the preprint server for health sciences 2023 Chen C, Douglas MP, Ragavan MV, Phillips KA, Jansen JP -
The Health Inequality Impact of Liquid Biopsy to Inform First-Line Treatment of Advanced Non-Small Cell Lung Cancer: A Distributional Cost-Effectiveness Analysis.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2023 Jansen JP, Ragavan MV, Chen C, Douglas MP, Phillips KA -
Perspectives of private payers on multicancer early-detection tests: informing research, implementation, and policy.
Health affairs scholar 2023 Trosman JR, Weldon CB, Kurian AW, Pasquinelli MM, Kircher SM, Martin N, Douglas MP, Phillips KA
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HTA82 Clinical Validity and Utility of Circulating Tumor DNA (ctDNA) Testing in Advanced Non-Small Cell Lung Cancer (aNSCLC): A Systematic Literature Review and Meta-Analysis.
Value in Health 2023 C. Chen, M.P. Douglas, M.V. Ragavan, K. Phillips, J. Jansen -
Private Payer and Medicare Coverage Policies for Use of Circulating Tumor DNA Tests in Cancer Diagnostics and Treatment.
Journal of the National Comprehensive Cancer Network : JNCCN 2023 Douglas MP, Ragavan MV, Chen C, Kumar A, Gray SW, Blakely CM, Phillips KA -
Genetic counselors' experience with reimbursement and patient out-of-pocket cost for multi-cancer gene panel testing for hereditary cancer syndromes.
Journal of genetic counseling 2022 Weldon CB, Trosman JR, Liang SY, Douglas MP, Scheuner MT, Kurian A, Schaa KL, Roscow B, Erwin D, Phillips KA -
Analyzing Precision Medicine Utilization with Real-World Data: A Scoping Review.
Journal of personalized medicine 2022 Douglas MP, Kumar A -
Multicancer Screening Tests: Anticipating And Addressing Considerations For Payer Coverage And Patient Access.
Health affairs (Project Hope) 2022 Deverka PA, Douglas MP, Phillips KA -
Geriatricians' Perspectives on the Multiple Dimensions of Utility of Genetic Testing for Alzheimer's Disease: A Qualitative Study.
Journal of Alzheimer's disease : JAD 2022 Arias JJ, Lin GA, Tyler AM, Douglas MP, Phillips KA -
US private payers' perspectives on insurance coverage for genome sequencing versus exome sequencing: A study by the Clinical Sequencing Evidence-Generating Research Consortium (CSER).
Genetics in medicine : official journal of the American College of Medical Genetics 2021 Phillips KA, Trosman JR, Douglas MP, Gelb BD, Ferket BS, Hindorff LA, Slavotinek AM, Berg JS, Russell HV, Devine B, Greve V, Smith HS -
Hereditary cancer panel testing challenges and solutions for the latinx community: costs, access, and variants.
Journal of community genetics 2021 Douglas MP, Lin GA, Trosman JR, Phillips KA -
Multicancer hereditary syndrome testing: Genetic counselors’ perspectives.
Journal of Clinical Oncology 2021 Christine B. Weldon, Su-Ying Liang, Kathryn A. Phillips, Michael P. Douglas, Maren Theresa Scheuner, Allison W. Kurian, Kendra Schaa, Breanna Roscow, Deanna Erwin, Julia R. Trosman -
Influence of payer coverage and out-of-pocket costs on ordering of NGS panel tests for hereditary cancer in diverse settings.
Journal of genetic counseling 2021 Lin GA, Trosman JR, Douglas MP, Weldon CB, Scheuner MT, Kurian A, Phillips KA -
Multicancer hereditary syndrome testing: Genetic counselors’ perspectives.
Journal of Clinical Oncology 2021 Christine B. Weldon, Su-Ying Liang, Kathryn A Phillips, Michael P Douglas, Maren Theresa Scheuner, Allison W. Kurian, Kendra Schaa, Breanna Roscow, Deanna Erwin, Julia Rachel Trosman -
Laboratory business models and practices: implications for availability and access to germline genetic testing.
Genetics in medicine : official journal of the American College of Medical Genetics 2021 Scheuner MT, Douglas MP, Sales P, Ackerman SL, Phillips KA -
OP511 Financing of germline testing: implications for availability and access.
Molecular Genetics and Metabolism 2021 Grace Lin, Maren Scheuner, Julia Trosman, Paloma Sales, Sara Ackerman, Michael Douglas, Christine Weldon, Allison Kurian, Kathryn Phillips -
Availability and funding of clinical genomic sequencing globally.
BMJ global health 2021 Phillips KA, Douglas MP, Wordsworth S, Buchanan J, Marshall DA -
Private payer coverage policies for ApoE-e4 genetic testing.
Genetics in medicine : official journal of the American College of Medical Genetics 2021 Arias JJ, Tyler AM, Douglas MP, Phillips KA -
Expanding Use of Clinical Genome Sequencing and the Need for More Data on Implementation.
JAMA 2020 Phillips KA, Douglas MP, Marshall DA -
PCV3 Global Landscape of Clinical Genomic Sequencing: Who, Where, and How?.
Value in Health Regional Issues 2020 K. Phillips, S. Wordsworth, D. Regier, D. Marshall, M.P. Douglas, J. Buchanan -
Private Payer and Medicare Coverage for Circulating Tumor DNA Testing: A Historical Analysis of Coverage Policies From 2015 to 2019.
Journal of the National Comprehensive Cancer Network : JNCCN 2020 Douglas MP, Gray SW, Phillips KA -
Use of Real-World Evidence in US Payer Coverage Decision-Making for Next-Generation Sequencing-Based Tests: Challenges, Opportunities, and Potential Solutions.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2020 Deverka PA, Douglas MP, Phillips KA -
Insights From a Temporal Assessment of Increases in US Private Payer Coverage of Tumor Sequencing From 2015 to 2019.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2020 Trosman JR, Douglas MP, Liang SY, Weldon CB, Kurian AW, Kelley RK, Phillips KA -
Perspectives of US private payers on insurance coverage for pediatric and prenatal exome sequencing: Results of a study from the Program in Prenatal and Pediatric Genomic Sequencing (P3EGS).
Genetics in medicine : official journal of the American College of Medical Genetics 2019 Trosman JR, Weldon CB, Slavotinek A, Norton ME, Douglas MP, Phillips KA -
Emergence of Hybrid Models of Genetic Testing Beyond Direct-to-Consumer or Traditional Labs.
JAMA 2019 Phillips KA, Trosman JR, Douglas MP -
New Medicare Coverage Policy for Next-Generation Tumor Sequencing: A Key Shift in Coverage Criteria With Broad Implications Beyond Medicare.
JCO precision oncology 2018 Phillips KA, Trosman JR, Weldon CB, Douglas MP -
The Global Market for Next-Generation Sequencing Tests Continues Its Torrid Pace.
The Journal of precision medicine 2018 Phillips KA, Douglas MP -
Private payer coverage policies for exome sequencing (ES) in pediatric patients: trends over time and analysis of evidence cited.
Genetics in medicine : official journal of the American College of Medical Genetics 2018 Douglas MP, Parker SL, Trosman JR, Slavotinek AM, Phillips KA -
Genetic Test Availability And Spending: Where Are We Now? Where Are We Going?
Health affairs (Project Hope) 2018 Phillips KA, Deverka PA, Hooker GW, Douglas MP -
Insurance coverage for genomic tests.
Science (New York, N.Y.) 2018 Phillips KA, Trosman JR, Deverka PA, Quinn B, Tunis S, Neumann PJ, Chambers JD, Garrison LP, Douglas MP, Weldon CB -
Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial.
Genetics in medicine : official journal of the American College of Medical Genetics 2018 Christensen KD, Vassy JL, Phillips KA, Blout CL, Azzariti DR, Lu CY, Robinson JO, Lee K, Douglas MP, Yeh JM, Machini K, Stout NK, Rehm HL, McGuire AL, Green RC, Dukhovny D, MedSeq Project -
Corrigendum: What are people willing to pay for whole-genome sequencing information, and who decides what they receive?
Genetics in medicine : official journal of the American College of Medical Genetics 2017 Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA -
EXAMINING EVIDENCE IN U.S. PAYER COVERAGE POLICIES FOR MULTI-GENE PANELS AND SEQUENCING TESTS.
International journal of technology assessment in health care 2017 Chambers JD, Saret CJ, Anderson JE, Deverka PA, Douglas MP, Phillips KA -
Payer coverage policies for multigene tests.
Nature biotechnology 2017 Phillips KA, Deverka PA, Trosman JR, Douglas MP, Chambers JD, Weldon CB, Dervan AP -
The price of whole-genome sequencing may be decreasing, but who will be sequenced?
Personalized medicine 2017 Marshall DA, MacDonald KV, Robinson JO, Barcellos LF, Gianfrancesco M, Helm M, McGuire A, Green RC, Douglas MP, Goldman MA, Phillips KA -
Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.
Genetics in medicine : official journal of the American College of Medical Genetics 2017 Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP -
Payer Coverage for Hereditary Cancer Panels: Barriers, Opportunities, and Implications for the Precision Medicine Initiative.
Journal of the National Comprehensive Cancer Network : JNCCN 2017 Trosman JR, Weldon CB, Douglas MP, Kurian AW, Kelley RK, Deverka PA, Phillips KA -
"What Goes Around Comes Around": Lessons Learned from Economic Evaluations of Personalized Medicine Applied to Digital Medicine.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2017 Phillips KA, Douglas MP, Trosman JR, Marshall DA -
Decision Making on Medical Innovations in a Changing Health Care Environment: Insights from Accountable Care Organizations and Payers on Personalized Medicine and Other Technologies.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2017 Trosman JR, Weldon CB, Douglas MP, Deverka PA, Watkins JB, Phillips KA -
Payer decision making for next-generation sequencing-based genetic tests: insights from cell-free DNA prenatal screening.
Genetics in medicine : official journal of the American College of Medical Genetics 2016 Dervan AP, Deverka PA, Trosman JR, Weldon CB, Douglas MP, Phillips KA -
What are people willing to pay for whole-genome sequencing information, and who decides what they receive?
Genetics in medicine : official journal of the American College of Medical Genetics 2016 Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA -
Availability and payer coverage of BRCA1/2 tests and gene panels.
Nature biotechnology 2015 Clain E, Trosman JR, Douglas MP, Weldon CB, Phillips KA -
Economic evidence on identifying clinically actionable findings with whole-genome sequencing: a scoping review.
Genetics in medicine : official journal of the American College of Medical Genetics 2015 Douglas MP, Ladabaum U, Pletcher MJ, Marshall DA, Phillips KA -
Addressing lack of US insurance coverage of Cancer Hereditary Multiplex Testing (CHMT).
Journal of Clinical Oncology 2015 Julia Rachel Trosman, Christine B. Weldon, Allison W. Kurian, Michael P Douglas, Robin Kate Kelley, Kathryn A Phillips -
PND45 What are people willing to pay for whole genome sequencing information?.
Value in Health 2015 D.A. Marshall, J.M. Gonzalez, F.R. Johnson, A. Pugh, K.V. MacDonald, M.P. Douglas, K.A. Phillips -
Key emerging themes for assessing the cost-effectiveness of reporting incidental findings.
Genetics in medicine : official journal of the American College of Medical Genetics 2015 Phillips KA, Ladabaum U, Pletcher MJ, Marshall DA, Douglas MP -
Consumer familiarity, perspectives and expected value of personalized medicine with a focus on applications in oncology.
Personalized medicine 2015 Garfeld S, Douglas MP, MacDonald KV, Marshall DA, Phillips KA -
Genomic sequencing: assessing the health care system, policy, and big-data implications.
Health affairs (Project Hope) 2014 Phillips KA, Trosman JR, Kelley RK, Pletcher MJ, Douglas MP, Weldon CB -
Prioritizing genomic applications for action by level of evidence: a horizon-scanning method.
Clinical pharmacology and therapeutics 2014 Dotson WD, Douglas MP, Kolor K, Stewart AC, Bowen MS, Gwinn M, Wulf A, Anders HM, Chang CQ, Clyne M, Lam TK, Schully SD, Marrone M, Feero WG, Khoury MJ -
Horizon scanning for translational genomic research beyond bench to bedside.
Genetics in medicine : official journal of the American College of Medical Genetics 2014 Clyne M, Schully SD, Dotson WD, Douglas MP, Gwinn M, Kolor K, Wulf A, Bowen MS, Khoury MJ -
The economic value of personalized medicine tests: what we know and what we need to know.
Genetics in medicine : official journal of the American College of Medical Genetics 2013 Phillips KA, Ann Sakowski J, Trosman J, Douglas MP, Liang SY, Neumann P -
Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review.
Genetics in medicine : official journal of the American College of Medical Genetics 2013 Palomaki GE, Melillo S, Marrone M, Douglas MP -
Use of genomic profiling to assess risk for cardiovascular disease and identify individualized prevention strategies--a targeted evidence-based review.
Genetics in medicine : official journal of the American College of Medical Genetics 2010 Palomaki GE, Melillo S, Neveux L, Douglas MP, Dotson WD, Janssens AC, Balkite EA, Bradley LA -
Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review.
Genetics in medicine : official journal of the American College of Medical Genetics 2009 Palomaki GE, Bradley LA, Douglas MP, Kolor K, Dotson WD -
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group.
Genetics in medicine : official journal of the American College of Medical Genetics 2009 Teutsch SM, Bradley LA, Palomaki GE, Haddow JE, Piper M, Calonge N, Dotson WD, Douglas MP, Berg AO, EGAPP Working Group -
Taxonomic variation in the Mycobacterium fortuitum third biovariant complex: description of Mycobacterium boenickei sp. nov., Mycobacterium houstonense sp. nov., Mycobacterium neworleansense sp. nov. and Mycobacterium brisbanense sp. nov. and recognition of Mycobacterium porcinum from human clinical isolates.
International journal of systematic and evolutionary microbiology 2004 Schinsky MF, Morey RE, Steigerwalt AG, Douglas MP, Wilson RW, Floyd MM, Butler WR, Daneshvar MI, Brown-Elliott BA, Wallace RJ, McNeil MM, Brenner DJ, Brown JM -
Paracoccus yeeii sp. nov. (formerly CDC group EO-2), a novel bacterial species associated with human infection.
Journal of clinical microbiology 2003 Daneshvar MI, Hollis DG, Weyant RS, Steigerwalt AG, Whitney AM, Douglas MP, Macgregor JP, Jordan JG, Mayer LW, Rassouli SM, Barchet W, Munro C, Shuttleworth L, Bernard K -
Cellular fatty acid composition of Lautropia mirabilis.
Journal of clinical microbiology 2001 Daneshvar MI, Douglas MP, Weyant RS -
Enterococcus porcinus sp. nov. and Enterococcus ratti sp. nov., associated with enteric disorders in animals.
International journal of systematic and evolutionary microbiology 2001 Teixeira LM, Carvalho MG, Espinola MM, Steigerwalt AG, Douglas MP, Brenner DJ, Facklam RR -
Assignment of CDC weak oxidizer group 2 (WO-2) to the genus Pandoraea and characterization of three new Pandoraea genomospecies.
Journal of clinical microbiology 2001 Daneshvar MI, Hollis DG, Steigerwalt AG, Whitney AM, Spangler L, Douglas MP, Jordan JG, MacGregor JP, Hill BC, Tenover FC, Brenner DJ, Weyant RS -
DNA damage caused by common cytological fixatives.
Mutation research 1998 Douglas MP, Rogers SO