Michael Bokoch, MD, PhD
Associate Professor
Anesthesia
School of Medicine
Awards
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- Short-Term Mentor Award (Summer Explore program), UCSF, 2023
- William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2023
- William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2020
- William K. Hamilton Award for Excellence in Resident Teaching, UCSF Anesthesia, 2019
- Jeffrey A. Katz Award, for work ethic and professionalism in patient care, UCSF Anesthesia, 2015
- Excellence in Medical Student Teaching Award, UCSF, 2013
- Allen B. Barbour Award, Excellence in Clinical Medicine, Stanford University, 2011
- Daniel Burke Prize, Excellence in both Biology and Chemistry, Case Western Reserve University, 2003
- John Schoff Millis Award, Senior with the best academic record, Case Western Reserve University, 2003
- Mateescu Student Citizenship Award, Dept. of Chemistry, Case Western Reserve University, 2003
- Phi Beta Kappa, Alpha of Ohio Chapter, Case Western Reserve University, 2003
- Olin Freeman Tower Prize, Excellence in Physical Chemistry, Case Western Reserve University, 2002
- Merck Index Award, Excellence in Chemistry, Case Western Reserve University, 2001
- Trustees' Scholarship, Case Western Reserve University, 1999-2003
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2018
- Fellowship Liver Transplant Anesthesia UCSF 2017
- Residency Anesthesia UCSF 2016
- M.D. School of Medicine Stanford University 2011
- Ph.D. Biophysics Stanford University 2010
- B.S./B.A. Biology/Chemistry Case Western Reserve University 2003
Interests
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- acute kidney injury
- molecular pharmacology
- liver transplant anesthesia
- endothelium
- beta blockers
- G-protein-coupled receptors
- vascular anesthesia
- coagulation
- pupillometry
Websites
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- UCSF Transplant Anesthesia Research Group (targ.ucsf.edu)
Grants and Projects
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- Endothelial Activation by Liver Reperfusion Injury in Transplantation, International Anesthesia Research Society, 2021-2023
- Angiotensin II in Liver Transplantation: a pilot randomized controlled trial, UCSF Liver Center Pilot/Feasibility Grant for New Investigator, 2021-2022
- Early Detection of Acute Kidney Injury (AKI) by NephroCheck® in the MHALT Trial, BioMérieux, Inc., 2020-2021
- A Randomized Controlled Trial of Mild Hypothermia to Prevent Acute Kidney Injury in Liver Transplantation, UCSF REAC, 2019-2021
- Mild Hypothermia to prevent Acute kidney injury in Liver Transplantation (MHALT), Department of Anesthesia & Perioperative Care, 2018-2019
Publications (32)
Top publication keywords:
Deamino Arginine VasopressinThoraxLiving DonorsAcute Kidney InjuryLiver TransplantationPupilHemostaticsRenin-Angiotensin SystemEnd Stage Liver DiseaseCentral Venous CathetersLung InjuryLactonesHypotensionReflex, PupillaryReceptor, PAR-1
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Angiotensin II in liver transplantation (AngLT-1): protocol of a randomised, double-blind, placebo-controlled trial.
BMJ open 2023 Bokoch MP, Tran AT, Brinson EL, Marcus SG, Reddy M, Sun E, Roll GR, Pardo M, Fields S, Adelmann D, Kothari RP, Legrand M -
Norepinephrine versus phenylephrine for treating hypotension during general anaesthesia in adult patients undergoing major noncardiac surgery: a multicentre, open-label, cluster-randomised, crossover, feasibility, and pilot trial.
British journal of anaesthesia 2023 Legrand M, Kothari R, Fong N, Palaniappa N, Boldt D, Chen LL, Kurien P, Gabel E, Sturgess-DaPrato J, Harhay MO, Pirracchio R, Bokoch MP, VEGA-1 trial investigators -
Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.
Biochemistry 2018 Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR -
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature 2010 Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK -
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.
Proceedings of the National Academy of Sciences of the United States of America 2007 Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK
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Current Anesthesiology Reports
Goal-Directed Therapy in Liver Surgery 2024 Marcus, SG Syed, S Anderson, AL Bokoch, MP -
Association between peripheral perfusion index and postoperative acute kidney injury in major noncardiac surgery patients receiving continuous vasopressors: a post hoc exploratory analysis of the VEGA-1 trial.
British journal of anaesthesia 2024 Krone S, Bokoch MP, Kothari R, Fong N, Tallarico RT, Sturgess-DaPrato J, Pirracchio R, Zarbock A, Legrand M -
Mismatched Postsurgical Opioid Prescription to Liver Transplant Patients: A Retrospective Cohort Study From a Single High-volume Transplant Center.
Transplantation 2024 Chen VJ, Guan LS, Bokoch MP, Langnas E, Kothari R, Croci R, Campbell LJ, Quan D, Freise C, Guan Z -
Lactate concentration at the end of liver transplant: Early predictor of graft function or just one piece of the puzzle?
Clinical transplantation 2023 Galli AM, Kothari R, Adelmann D, Holm Z, Bokoch MP, De Gasperi A, Niemann CU, Kolodzie K -
Real-world implementation of normothermic machine perfusion: A detailed analysis of intraoperative and early postoperative impact.
Clinical transplantation 2023 Dixon W, Sheetz K, Adelmann D, Bokoch M, Reddy M, Kothari R, Roberts JP, Syed S, Feng S, Roll G -
Pulmonary Injury Causing a Massive Air Leak During Liver Transplantation: A Case Report and Discussion of Decision-Making.
A&A practice 2023 Mavrothalassitis O, Marcus SG, Roll GR, Tallarico RT, Bokoch MP -
Intraoperative Use of Albumin in Major Noncardiac Surgery: Incidence, Variability, and Association With Outcomes.
Annals of surgery 2022 Lazzareschi DV, Fong N, Mavrothalassitis O, Whitlock EL, Chen CL, Chiu C, Adelmann D, Bokoch MP, Chen LL, Liu KD, Pirracchio R, Mathis MR, Legrand M, MPOG Collaborators -
Prepectoral Breast Reconstruction Reduces Opioid Consumption and Pain After Mastectomy: A Head-to-Head Comparison With Submuscular Reconstruction.
Annals of plastic surgery 2022 Holland M, Su P, Piper M, Withers J, Harbell MW, Bokoch MP, Sbitany H -
Optimizing the Design and Analysis of Future AKI Trials.
Journal of the American Society of Nephrology : JASN 2022 Legrand M, Bagshaw SM, Koyner JL, Schulman IH, Mathis MR, Bernholz J, Coca S, Gallagher M, Gaudry S, Liu KD, Mehta RL, Pirracchio R, Ryan A, Steubl D, Stockbridge N, Erlandsson F, Turan A, Wilson FP, … -
The Yin and Yang of the Renin-Angiotensin-Aldosterone System in Acute Kidney Injury.
American journal of respiratory and critical care medicine 2021 Legrand M, Bokoch MP -
The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation.
Transplantation 2020 Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D -
Pulmonary Hypertension and Mortality in Patients Awaiting Kidney Transplant: Cause for Concern and Potential Opportunity.
Transplantation 2020 Bokoch MP, Findlay JY -
Is nitric oxide the forgotten nephroprotective treatment during cardiac surgery?
Annals of intensive care 2020 Khorashadi M, Bokoch MP, Legrand M -
Intravenous Fluid Management Practices in Kidney Transplant Patients: A Multicenter Observational Cohort Pilot Study.
Seminars in cardiothoracic and vascular anesthesia 2020 Efune GE, Zerillo J, Zhou G, Mazzeffi MA, Demaria S, Wang C, Society for the Advancement of Transplant Anesthesia Research Committee Writing Group -
Central Venous Catheter in the Internal Mammary Vein.
Anesthesiology 2019 House LM, Yen A, Bokoch MP -
Management of Hyponatremia in End-Stage Liver Disease.
Critical Care for Potential Liver Transplant Candidates 2019 Vanessa G. Henke, Michael P. Bokoch, Linda L. Liu -
Desmopressin Reverses Overly Rapid Serum Sodium Correction in a Hyponatremic Patient Undergoing Living Donor Liver Transplantation: A Case Report.
A&A practice 2018 Brinson EL, Yu JS, Liu LL, Bokoch MP -
Suppression of pupillary unrest by general anesthesia and propofol sedation.
Journal of clinical monitoring and computing 2018 Behrends M, Larson MD, Neice AE, Bokoch MP -
Rapid Ventricular Pacing for Landing Zone Precision During Thoracic Endovascular Aortic Arch Repair: A Case Series.
Journal of cardiothoracic and vascular anesthesia 2017 Bokoch MP, Hiramoto JS, Lobo EP, Shalabi A -
Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest.
Anesthesia and analgesia 2017 Neice AE, Behrends M, Bokoch MP, Seligman KM, Conrad NM, Larson MD -
Fentanyl, an agonist at the mu opioid receptor, depresses pupillary unrest.
Autonomic neuroscience : basic & clinical 2015 Bokoch MP, Behrends M, Neice A, Larson MD -
From the journal archives: cyclopropane: induction and recovery with a bang!
Canadian journal of anaesthesia = Journal canadien d'anesthesie 2014 Bokoch MP, Gelb AW -
The dynamic process of β(2)-adrenergic receptor activation.
Cell 2013 Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK -
Lysine methylation strategies for characterizing protein conformations by NMR.
Journal of biomolecular NMR 2012 Larda ST, Bokoch MP, Evanics F, Prosser RS -
FRET-based measurement of GPCR conformational changes.
Methods in molecular biology (Clifton, N.J.) 2009 Granier S, Kim S, Fung JJ, Bokoch MP, Parnot C -
Cytochrome c conformations resolved by the photon counting histogram: watching the alkaline transition with single-molecule sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2005 Perroud TD, Bokoch MP, Zare RN -
Steady-state oxidation of cholesterol catalyzed by cholesterol oxidase in lipid bilayer membranes on platinum electrodes.
Analytica Chimica Acta 2004 Michael P Bokoch, Anando Devadoss, Mariela S Palencsár, James D Burgess