Melissa Medvedev, MD, PhD
Associate Professor
Pediatrics
School of Medicine
Dr. Melissa Medvedev (Morgan) is an Associate Professor of Pediatrics (Neonatology). She is a physician-scientist with a background in clinical research/trials, global health, and health technology innovation. Her research focuses on risk prediction and the evaluation of maternal, neonatal, and early childhood interventions to promote survival and prevent disability.
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Dr. Medvedev derived and validated a simplified score to predict mortality among newborns ≤2000g (NMR-2000), using data from the UK and The Gambia. She is co-PI of the OMWaNA study, a randomized trial evaluating the impact of kangaroo mother care (KMC) initiated before stabilization on mortality within 7 and 28 days relative to standard care among neonates at five Ugandan hospitals. Trial enrollment has been completed and results are expected in fall 2022.
Dr. Medvedev received her MD from the University of Texas Houston and completed clinical training in Pediatrics and Neonatal-Perinatal Medicine at UCSF. She obtained her MSc in Global Health Science from the University of Oxford and her PhD in Epidemiology and Medical Statistics from the London School of Hygiene & Tropical Medicine. Her thesis focused on quantifying neonatal mortality risk and informing the design of the OMWaNA trial using mixed methods. She completed postdoctoral fellowships in preterm birth research at UCSF and biodesign innovation at Stanford University.
Dr. Medvedev serves on the WHO/UNICEF Every Newborn Measurement Improvement KMC Working Group, the UNICEF/NEST360 Target Product Profiles Working Group, and the NEST360 COVID-19 and Education Working Groups. She is a member of the WHO Maternal, Newborn, Child & Adolescent Health COVID-19 Research Network and the COVID-19 Small and Sick Newborn Care Collaborative Group. In partnership with these groups, Dr. Medvedev co-led a comparative risk analysis of deaths averted by KMC versus mortality due to SARS-CoV-2 infection, and a global survey exploring the impact of COVID-19 on neonatal care.
Awards
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- Loan Repayment Program Award, National Institutes of Health, 2021
- Woodruff Medal for Outstanding Doctoral Thesis, London School of Hygiene & Tropical Medicine, 2020
- Loan Repayment Program Award, National Institutes of Health, 2018
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 11/2020
- PhD Epidemiology & Medical Statistics London School of Hygiene & Tropical Medicine 08/2020
- Fellowship Biodesign Innovation Stanford University 06/2019
- Fellowship Preterm Birth Initiative (research) University of California San Francisco 06/2017
- Fellowship Neonatal-Perinatal Medicine University of California San Francisco 06/2016
- Residency Pediatrics University of California San Francisco 06/2013
- MD Medicine University of Texas School of Medicine 05/2010
- MSc Global Health Science University of Oxford 09/2006
Interests
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- statistical analysis
- sub-Saharan Africa
- pulse oximetry
- clinical decision support
- oxygen delivery
- machine learning
- big data
- risk prediction
- maternal
- newborn
- child health
- low birthweight
- south Asia
- health technology innovation
- preterm birth
- natural language processing
- simulation training
- clinical trials
- kangaroo mother care
- epidemiology
- global health
Websites
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- @@melissacmorgan on Twitter (twitter.com)
Grants and Projects
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- The OMWaNA Study: Operationalizing kangaroo Mother care among clinically unstable low birth Weight Neonates in Africa, NIH, 2018-2024
- The OMWaNA Study: Operationalizing kangaroo Mother care among unstable low birth Weight Neonates in Africa: developing and validating a clinical stability index to help providers determine eligibility, Thrasher Research Fund, 2016-2018
- Feasibility and acceptability of kangaroo mother care among clinically unstable infants weighing 2000 grams or less in Uganda, UCSF Preterm Birth Initiative, 2015-2017
- Improving quality of obstetric and neonatal care through mentoring and simulation training: a collaboration in Bihar, Bill and Melinda Gates Foundation, 2014-2017
- Pulse oximetry to guide oxygen therapy in neonates born at a resource-limited hospital in Nairobi, Kenya, UCSF Resource Allocation Program, 2013-2015
- Implementation of a Neonatal Transcutaneous Bilirubin Screening Program in Rural India, UCSF Clinical and Translational Science Institute, 2011-2012
Publications (36)
Top publication keywords:
Perinatal DeathInfant HealthOximetryInfant, Newborn, DiseasesHealth FacilitiesOxygen Inhalation TherapyMentorsSimulation TrainingKangaroo-Mother Care MethodInfant, NewbornInfant MortalityPerinatal CareInfant CareHyperbilirubinemia, NeonatalInfant, Low Birth Weight
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Health facility assessment of small and sick newborn care in low- and middle-income countries: systematic tool development and operationalisation with NEST360 and UNICEF.
BMC pediatrics 2024 Penzias RE, Bohne C, Ngwala SK, Zimba E, Lufesi N, Rashid E, Gicheha E, Odedere O, Dosunmu O, Tillya R, Shabani J, Cross JH, Liaghati-Mobarhan S, Chiume M, Banda G, Chalira A, Wainaina J, Gathara D, … -
Target product profiles for neonatal care devices: systematic development and outcomes with NEST360 and UNICEF.
BMC pediatrics 2023 Kirby RP, Molyneux EM, Dube Q, McWhorter C, Bradley BD, Gartley M, Oden ZM, Richards-Kortum R, Werdenberg-Hall J, Kumara D, Liaghati-Mobarhan S, Heenan M, Bond M, Ezeaka C, Salim N, Irimu G, … -
Assessing a digital technology-supported community child health programme in India using the Social Return on Investment framework.
PLOS digital health 2023 Patil M, Qureshi A, Naydenova E, Bang A, Halbert J, De Vos M, Nair P, Patil M, Medvedev MM -
Process and costs for readiness to safely implement immediate kangaroo mother care: a mixed methods evaluation from the OMWaNA trial at five hospitals in Uganda.
BMC health services research 2023 Medvedev MM, Tumukunde V, Kirabo-Nagemi C, Greco G, Mambule I, Katumba K, Waiswa P, Tann CJ, Elbourne D, Allen E, Ekirapa-Kiracho E, Pitt C, Lawn JE -
Infant mortality and growth failure after oral azithromycin among low birthweight and underweight neonates: A subgroup analysis of a randomized controlled trial.
PLOS global public health 2023 Bountogo M, Sié A, Zakane A, Compaoré G, Ouédraogo T, Brogdon J, Lebas E, Nyatigo F, Medvedev MM, Arnold BF, Lietman TM, Oldenburg CE, NAITRE Study Team
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Predicting the risk of 7-day readmission in late preterm infants in California: A population-based cohort study.
Health science reports 2023 Amsalu R, Oltman SP, Medvedev MM, Baer RJ, Rogers EE, Shiboski SC, Jelliffe-Pawlowski L -
Incidence, Risk Factors, and Reasons for 30-Day Hospital Readmission Among Healthy Late Preterm Infants.
Hospital pediatrics 2022 Amsalu R, Oltman SP, Baer RJ, Medvedev MM, Rogers EE, Jelliffe-Pawlowski L -
Small and sick newborn care during the COVID-19 pandemic: global survey and thematic analysis of healthcare providers' voices and experiences.
BMJ global health 2021 Rao SPN, Minckas N, Medvedev MM, Gathara D, Y N P, Seifu Estifanos A, Silitonga AC, Jadaun AS, Adejuyigbe EA, Brotherton H, Arya S, Gera R, Ezeaka CV, Gai A, Gobezayehu AG, Dube Q, Kumar A, Naburi H, … -
Preterm care during the COVID-19 pandemic: A comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection.
EClinicalMedicine 2021 Minckas N, Medvedev MM, Adejuyigbe EA, Brotherton H, Chellani H, Estifanos AS, Ezeaka C, Gobezayehu AG, Irimu G, Kawaza K, Kumar V, Massawe A, Mazumder S, Mambule I, Medhanyie AA, Molyneux EM, Newton … -
Informing the design of a trial of kangaroo mother care initiated before stabilisation amongst small and sick newborns in a sub-Saharan African context using mixed methods. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine
Informing the design of a trial of kangaroo mother care initiated before stabilisation amongst small and sick newborns in a sub-Saharan African context using mixed methods. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine 2020 Medvedev MM -
Management of mother-newborn dyads in the COVID-19 era.
The Lancet. Child & adolescent health 2020 Medvedev MM -
Cohort study of neonatal resuscitation skill retention in frontline healthcare facilities in Bihar, India, after PRONTO simulation training.
BMJ paediatrics open 2020 Higgins BV, Medvedev MM, Spindler H, Ghosh R, Longkumer O, Cohen SR, Das A, Gore A, Mahapatra T, Walker DM -
Development and validation of a simplified score to predict neonatal mortality risk among neonates weighing 2000 g or less (NMR-2000): an analysis using data from the UK and The Gambia.
The Lancet. Child & adolescent health 2020 Medvedev MM, Brotherton H, Gai A, Tann C, Gale C, Waiswa P, Elbourne D, Lawn JE, Allen E -
Operationalising kangaroo Mother care before stabilisation amongst low birth Weight Neonates in Africa (OMWaNA): protocol for a randomised controlled trial to examine mortality impact in Uganda.
Trials 2020 Medvedev MM, Tumukunde V, Mambule I, Tann CJ, Waiswa P, Canter RR, Hansen CH, Ekirapa-Kiracho E, Katumba K, Pitt C, Greco G, Brotherton H, Elbourne D, Seeley J, Nyirenda M, Allen E, Lawn JE -
Training and evaluating simulation debriefers in low-resource settings: lessons learned from Bihar, India.
BMC medical education 2020 Raney JH, Medvedev MM, Cohen SR, Spindler H, Ghosh R, Christmas A, Das A, Gore A, Mahapatra T, Walker D -
Diagnosis and management of postpartum hemorrhage and intrapartum asphyxia in a quality improvement initiative using nurse-mentoring and simulation in Bihar, India.
PloS one 2019 Ghosh R, Spindler H, Morgan MC, Cohen SR, Begum N, Gore A, Mahapatra T, Walker DM -
Assessment of a storage system to deliver uninterrupted therapeutic oxygen during power outages in resource-limited settings.
PloS one 2019 Calderon R, Morgan MC, Kuiper M, Nambuya H, Wangwe N, Somoskovi A, Lieberman D -
Does teamwork and communication improve with simulation training? An evaluation of simulation training videos in Bihar, India. East African Journal of Applied Health Monitoring and Evaluation
Does teamwork and communication improve with simulation training? An evaluation of simulation training videos in Bihar, India. East African Journal of Applied Health Monitoring and Evaluation 2019 Dyer JD, Morgan MC, Cohen SR, Ghosh R, Raney J, Spindler H, Mahapatra T, Christmas A, Walker DM -
Simulation-enhanced nurse mentoring to improve preeclampsia and eclampsia care: an education intervention study in Bihar, India.
BMC pregnancy and childbirth 2019 Raney JH, Morgan MC, Christmas A, Sterling M, Spindler H, Ghosh R, Gore A, Mahapatra T, Walker DM -
Clinical cascades as a novel way to assess physical readiness of facilities for the care of small and sick neonates in Kenya and Uganda.
PloS one 2018 Morgan MC, Spindler H, Nambuya H, Nalwa GM, Namazzi G, Waiswa P, Otieno P, Cranmer J, Walker DM -
Barriers and facilitators to the provision of optimal obstetric and neonatal emergency care and to the implementation of simulation-enhanced mentorship in primary care facilities in Bihar, India: a qualitative study.
BMC pregnancy and childbirth 2018 Morgan MC, Dyer J, Abril A, Christmas A, Mahapatra T, Das A, Walker DM -
Logistical, cultural, and structural barriers to immediate neonatal care and neonatal resuscitation in Bihar, India.
BMC pregnancy and childbirth 2018 Vail B, Morgan MC, Dyer J, Christmas A, Cohen SR, Joshi M, Gore A, Mahapatra T, Walker DM -
The power of practice: simulation training improving the quality of neonatal resuscitation skills in Bihar, India.
BMC pediatrics 2018 Vail B, Morgan MC, Spindler H, Christmas A, Cohen SR, Walker DM -
Kangaroo mother care for clinically unstable neonates weighing ≤2000 g: Is it feasible at a hospital in Uganda?
Journal of global health 2018 Morgan MC, Nambuya H, Waiswa P, Tann C, Elbourne D, Seeley J, Allen E, Lawn JE -
Video Monitoring a Simulation-Based Quality Improvement Program in Bihar, India.
Clinical simulation in nursing 2018 Dyer J, Spindler H, Christmas A, Shah MB, Morgan M, Cohen SR, Sterne J, Mahapatra T, Walker D -
Observation study showed that the continuity of skin-to-skin contact with low-birthweight infants in Uganda was suboptimal.
Acta paediatrica (Oslo, Norway : 1992) 2018 Watkins HC, Morgan MC, Nambuya H, Waiswa P, Lawn JE -
Pulse oximetry values of neonates admitted for care and receiving routine oxygen therapy at a resource-limited hospital in Kenya.
Journal of paediatrics and child health 2017 Morgan MC, Maina B, Waiyego M, Mutinda C, Aluvaala J, Maina M, English M -
Care of the mother-infant dyad: a novel approach to conducting and evaluating neonatal resuscitation simulation training in Bihar, India.
BMC pregnancy and childbirth 2017 Vail B, Spindler H, Morgan MC, Cohen SR, Christmas A, Sah P, Shah MB, Das A, Walker DM -
Video Analysis System as a Tool to Improve the Quality of Basic Emergency Obstetric and Neonatal Care through Simulation Training in Bihar, India
Annals of Global Health 2017 Janjua AT, Dyer J, Spindler H, Sterne J, Cohen S, Morgan M, Christmas A, Bharat Shah M, Das A, Walker D -
Oxygen saturation ranges for healthy newborns within 24 hours at 1800 m.
Archives of disease in childhood. Fetal and neonatal edition 2017 Morgan MC, Maina B, Waiyego M, Mutinda C, Aluvaala J, Maina M, English M -
Implementation of a neonatal transcutaneous bilirubin screening programme in rural India.
Paediatrics and international child health 2016 Morgan MC, Kumar GS, Kaiser SV, Seetharam S, Ruel TD -
Predictors of Neonatal Sepsis in Rural Karnataka, India
Asian Journal of Clinical Pediatrics and Neonatology 2013 Morgan MC, Ruel TD, Kumar GS, Sabnis AJ, Kaiser SV -
Cutaneous Manifestations of HIV Infection. In: Tyring S, Moore AY, Lupi O, eds. Mucocutaneous Manifestations of Viral Diseases
Cutaneous Manifestations of HIV Infection. In: Tyring S, Moore AY, Lupi O, eds. Mucocutaneous Manifestations of Viral Diseases. 2010 Morgan MC, Bartlett BL, Cockerell CJ, Cohen PR -
Cutaneous Resistance to Viral Infections. In: Tyring S, Moore AY, Lupi O, eds. Mucocutaneous Manifestations of Viral Diseases
Cutaneous Resistance to Viral Infections. In: Tyring S, Moore AY, Lupi O, eds. Mucocutaneous Manifestations of Viral Diseases. 2010 Morgan MC, Rashid RM, Memar OM, et al -
Factors affecting breastfeeding cessation after discontinuation of antiretroviral therapy to prevent mother-to-child transmission of HIV.
AIDS care 2010 Morgan MC, Masaba RO, Nyikuri M, Thomas TK -
The effect of phototherapy on neutrophils.
International immunopharmacology 2009 Morgan MC, Rashid RM