Mehrdad Arjomandi, MD
Professor
Medicine
School of Medicine

415-221-4810 ext. 24393

Dr. Arjomandi is a physician-scientist at UCSF who studies how the air we breathe and the environments we live in affect lung and heart health. His research aims to uncover how inhalational exposures to pollutants, toxicants, and tobacco smoke contribute to respiratory disease such as COPD and asthma and to translate this understanding into better strategies for prevention and care.

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A Professor of Medicine in the Divisions of Pulmonary, Critical Care, Allergy, and Sleep Medicine and Occupational, Environmental, and Climate Medicine, he leads the UCSF Human Exposure Laboratory and directs the San Francisco VA Airborne Hazards and Burn Pit Center of Excellence- a national program dedicated to advancing research and clinical care for veterans affected by deployment-related respiratory diseases.

Biography Dr. Arjomandi grew up in Ahvaz, a small city in southwestern Iran, and moved to the United States in 1986 in the aftermath of Iranian revolution (1979), Iraq's invasion of Iran (1980-88), and his family displacement inside Iran (1980-83). After arriving in California, he began his higher education at Los Angeles Pierce College before transferring to University of California San Diego in 1988, where he earned a bachelor's degree in molecular biology and completed a senior honors thesis in developmental biology in Dr. Richard Firtel’s lab. He then attended Stanford University School of Medicine in 1991, completing two predoctoral research fellowships in Dr. Etienne Emile Beaulieu’s lab at INSERM in Paris, France, and Dr. John Cooke’s vascular biology lab at Stanford. Dr. Arjomandi then completed a residency in internal medicine at UCLA (1996-99) and a fellowship in pulmonary and critical care at UCSF (2000-03). He completed three additional years of research fellowship funded by the American Lung Association and Chest Foundation before successfully competing for an NIH K23 award in 2006 and then joining the pulmonary and critical care faculty at UCSF and San Francisco General Hospital (SFGH). In 2008, he obtained a joint appointment at the San Francisco VA Health Care System (SFVAHCS).

Currently, Dr. Arjomandi is Professor of Medicine in the Divisions of Pulmonary, Critical Care, Allergy, and Sleep Medicine and Occupational, Environmental, and Climate Medicine at UCSF with a joint appointment at SFVAHCS. He serves as Director of the UCSF Human Exposure Laboratory, Director of the SFVAHCS Environmental Medicine Clinic, and Director of the SFVAHCS Airborne Hazard and Burn Pit Center of Excellence. He is also an Investigator at the UCSF Center for Tobacco Control Research and Education and an Affiliate Member of the UCSF Helen Diller Family Comprehensive Cancer Center.

Awards

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  • SFVAHCS Dept of Medicine HeRO Award, San Francisco VA Healthcare System, 2022

Education & Training

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  • Diversity, Equity, and Inclusion Champion Training University of California 2018
  • Certificate Genetic Approaches to Complex Heart, Lung and Blood Diseases The Jackson Laboratories (NIH/NHLBI) 10/2010
  • Certificate Mentor Development Program University of California, San Francisco 05/2010
  • Certificate Clinical Trial Design Course Veterans Affairs Cooperative Study Program 08/2009
  • Certificate Advanced Training in Clinical Research University of California, San Francisco 06/2003
  • Fellowship Pulmonary & Critical Care Medicine University of California, San Francisco 06/2003
  • Residency Internal Medicine University of California, Los Angeles 06/1999
  • MD MD Program Stanford University 06/1996
  • BA Molecular Biology University of California, San Diego 06/1991

Interests

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  • Pulmonary physiology in health and disease
  • Clinical epidemiology
  • “Big data” science including machine learning
  • Translational research
  • Cardiopulmonary health effects of air pollution and airborne hazards
  • Clinical trials and controlled human exposure studies of respiratory diseases
  • Lung cancer screening and biomarkers
  • Biological mechanisms of respiratory diseases
  • Pulmonary and Critical Care Medicine

Websites

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Grants and Projects

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  • Occult Cardiovascular Disease with Chronic Exposure to Secondhand Tobacco Smoke, Flight Attendant Medical Research Institute (FAMRI), 2020-2025
  • Lung Macrophage Populations and Functions in COPD-Susceptible Smokers (Pre-COPD Study), Department of Defense, 2020-2024
  • Characterization of Innate Immunity in Pollution-induced Exacerbation in Chronic Obstructive Pulmonary Disease (CO3PD Study), California TRDRP, 2019-2024

Publications (90)

Top publication keywords:
BerylliosisAlbuterolVeteransPulmonary EmphysemaAir PollutantsSpirometryLungInhalation ExposureSarcoidosisPulmonary Disease, Chronic ObstructiveBronchoalveolar Lavage FluidOzoneTobacco Smoke PollutionForced Expiratory VolumeLymphocytosis

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