Meghana Gadgil, MD, MPH
Associate Professor
Medicine
School of Medicine
My long-term goal is to prevent cardiometabolic disease in high-risk populations through a three-level approach: 1) clinical investigation of metabolomic processes at the individual level 2) improvements in chronic disease prevention inside the primary care office and 3) lifestyle changes with a focus on practical dietary interventions in the lived environment.
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At the individual level: My clinical research activities center on the metabolic processes connecting dietary intake and incident diabetes which are not yet well-characterized. I believe that further work with "omics" technologies can help to delineate the paths between diet and diabetes and identify targets for intervention. Inside the PCP's office: I am developing a program to improve postpartum transitions to primary care for women with gestational diabetes. In this program, we are identifying women with a pregnancy affected by GDM who are at high risk of transition to type 2 diabetes. We are then designing programs within our medical record system to track, improve postpartum follow-up and enroll patients into primary care. In the lived environment: A current research award from the Mount Zion Health Fund is supporting work improving the knowledge and uptake of prediabetes resources in the community. I have completed a pilot intervention study enrolling participants with prediabetes to evaluate the impact evaluation walnut intake on dietary quality, measures of prediabetes and metabolite expression. I am committed to work in the prevention of diabetes as it disproportionally impacts racial and ethnic minority populations. I also focus on research into the specific risk factors that women face in the development of diabetes, particularly those in the postpartum period. I feel strongly that each population should have appropriate and equitable guidance for a personalized care plan for the prevention of diabetes.
My future goals are to extend and individualize current knowledge about beneficial dietary and lifestyle interventions to prevent cardiometabolic disease, and to use digital tools and metabolomics to monitor responsiveness to these programs.
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2018
- MPH Johns Hopkins Bloomberg School of Public Health
- Johns Hopkins General Internal Medicine Fellowship
- MD Rutgers New Jersey Medical School
- Residency Internal Medicine Warren Alpert Medical School at Brown University
Interests
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- diet and nutrition
- preventing chronic disease after pregnancy complications
- prediabetes and type 2 diabetes
Grants and Projects
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- Associations of Targeted Metabolites with Protein, Saturated Fat and Glucose Homeostasis, NIDDK, 2022-2024
- Prevention of Type 2 Diabetes through Diet and Metabolomics, NIH, 2019-2022
Publications (40)
Top publication keywords:
Dietary CarbohydratesFeeding BehaviorDietDietary Fats, UnsaturatedAtherosclerosisNutritional StatusDeficiency DiseasesDietary ProteinsAcculturationBlood GlucoseDiabetes, GestationalMetabolic SyndromeCeramidesCardiovascular DiseasesDiabetes Mellitus, Type 2
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Predictors of weight and waist gain in US South Asians: Findings from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.
Research square 2024 Seetharaman S, Allen I, Gadgil M, Sriniva S, Topor L, Kanaya A -
Inverse association between total bilirubin and type 2 diabetes in U.S. South Asian males but not females.
PloS one 2024 Visaria A, Kanaya A, Setoguchi S, Gadgil M, Satagopan J -
Adipose tissue-derived metabolite risk scores and risk for type 2 diabetes in South Asians.
International journal of obesity (2005) 2024 Gadgil MD, Cheng J, Herrington DM, Kandula NR, Kanaya AM -
Reflecting on a Year at the Helm of Diabetes Care.
Diabetes care 2024 Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Fitzpatrick SL, Gadgil MD, Gastaldelli A, Gloyn AL, Green JB, Jastreboff AM, Kanaya AM, Kandula… -
Association of lipoprotein subfractions with incidence of type 2 diabetes among five U.S. Race and Ethnic groups: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multi-Ethnic study of Atherosclerosis (MESA).
Diabetes research and clinical practice 2023 Gadgil MD, Herrington DM, Singh SK, Kandula NR, Kanaya AM
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Untargeted metabolomic analysis investigating links between unprocessed red meat intake and markers of inflammation.
The American journal of clinical nutrition 2023 Wood AC, Graca G, Gadgil M, Senn MK, Allison MA, Tzoulaki I, Greenland P, Ebbels T, Elliott P, Goodarzi MO, Tracy R, Rotter JI, Herrington D -
Concordance between Dash Diet and Hypertension: Results from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.
Nutrients 2023 Hussain BM, Deierlein AL, Kanaya AM, Talegawkar SA, O'Connor JA, Gadgil MD, Lin Y, Parekh N -
Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis.
The Journal of nutrition 2023 Wood AC, Goodarzi MO, Senn MK, Gadgil MD, Graca G, Allison MA, Tzoulaki I, Mi MY, Greenland P, Ebbels T, Elliott P, Tracy RP, Herrington DM, Rotter JI -
Association of Physical Activity and Dietary Quality with Weight, Ectopic Fat, and Insulin Resistance in South Asian Men and Women: The MASALA Study.
Journal of Clinical Lipidology 2023 Cynthia Azam Ponir, Parag Anilkumar Chevli, Alka Kanaya, Meghana Gadgil, Luis A Rodriguez, Bharathi Upadhya, Morgana Mongraw-Chaffin -
OR02-05-23 Untargeted Metabolomic Analysis Reveals Inverse Associations Between Red Meat Intake and Two Anti-Inflammatory Amino Acids.
Current Developments in Nutrition 2023 Alexis Wood, Mackenzie Senn, Meghana Gadgil, Goncalo Graca, Matthew Allison, Ioanna Tzoulaki, Philip Greenland, Timothy Ebbels, Paul Elliott, Mark Goodarzi, Russell Tracy, Jerome Rotter, David … -
1399-P: Lipoprotein Subfractions and Type 2 Diabetes Incidence in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multiethnic Study of Atherosclerosis (MESA) Cohorts.
Diabetes 2023 MEGHANA D. GADGIL, DAVID M. HERRINGTON, SUKHMANI SINGH, NAMRATHA R. KANDULA, ALKA M. KANAYA -
205-LB: Using Metabolomic Biomarkers to Understand Relationships between Avocado Intake and Dysglycemia.
Diabetes 2023 ALEXIS WOOD, MARK O. GOODARZI, MEGHANA D. GADGIL, MATTHEW ALLISON, GONÇALO GRAÇA, MICHAEL Y. MI, PHILIP GREENLAND, DAVID M. HERRINGTON, JEROME I. ROTTER -
603-P: Changes in Insulin Resistance by Protein Source and Level of Saturated Fat—An Analysis of the Animal and Plant Protein and Cardiovascular Health (APPROACH) Trial.
Diabetes 2023 MEGHANA D. GADGIL, RONALD M. KRAUSS -
Metabolomic Profile of the Healthy Eating Index-2015 in the Multiethnic Study of Atherosclerosis.
The Journal of nutrition 2023 Gadgil MD, Wood AC, Karaman I, Graça G, Tzoulaki I, Zhong VW, Greenland P, Kanaya AM, Herrington DM -
Abstract MP12: Dash Diet and Its Components is Associated With Visceral Fat Area and Hepatic Attenuation Among South Asian Adults in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study (2010-2013).
Circulation 2023 Bridget M Hussain, Andrea L Deierlein, Sameera A Talegawkar, Joyce A O'Connor, Meghana Gadgil, Alka M Kanaya, Namratha Kandula, Yong Lin, Niyati Parekh -
"The Times They Are A-Changin'" at Diabetes Care.
Diabetes care 2023 Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Castle JR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Florez JC, Gadgil MD, Gastaldelli A, Green JB, Jastreboff AM, Kanaya AM, Kandula NR,… -
Prepregnancy Protein Source and BCAA Intake Are Associated with Gestational Diabetes Mellitus in the CARDIA Study.
International journal of environmental research and public health 2022 Gadgil MD, Ingram KH, Appiah D, Rudd J, Whitaker KM, Bennett WL, Shikany JM, Jacobs DR, Lewis CE, Gunderson EP -
Diet Patterns Are Associated With Circulating Metabolites and Lipid Profiles of South Asians in the United States.
The Journal of nutrition 2022 Gadgil MD, Kanaya AM, Sands C, Chekmeneva E, Lewis MR, Kandula NR, Herrington DM -
Diet Patterns Are Associated with Circulating Metabolites and Lipid Profiles of South Asians in the United States.
The Journal of nutrition 2022 Gadgil MD, Kanaya AM, Sands C, Chekmeneva E, Lewis MR, Kandula NR, Herrington DM -
Associations of NAFLD with circulating ceramides and impaired glycemia.
Diabetes research and clinical practice 2022 Gadgil MD, Sarkar M, Sands C, Lewis MR, Herrington DM, Kanaya AM -
Circulating metabolites and lipids are associated with glycaemic measures in South Asians.
Diabetic medicine : a journal of the British Diabetic Association 2020 Gadgil MD, Kanaya AM, Sands C, Lewis MR, Kandula NR, Herrington DM -
Acculturation is Associated with Dietary Patterns in South Asians in America.
Journal of immigrant and minority health 2020 Gadgil MD, Kandula NR, Kanaya AM -
Social network characteristics are correlated with dietary patterns among middle aged and older South Asians living in the United States (U.S.).
BMC nutrition 2020 Talegawkar SA, Lancki N, Jin Y, Siddique J, Gadgil M, Kanaya AM, Schneider JA, Van Horn L, De Koning L, Kandula NR -
Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus.
Journal of women's health (2002) 2018 Gadgil MD, Ehrlich SF, Zhu Y, Brown SD, Hedderson MM, Crites Y, Ferrara A -
Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk.
The Journal of nutrition 2018 Bhupathiraju SN, Guasch-Ferré M, Gadgil MD, Newgard CB, Bain JR, Muehlbauer MJ, Ilkayeva OR, Scholtens DM, Hu FB, Kanaya AM, Kandula NR -
The Association of Religious Affiliation with Overweight/Obesity Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.
Journal of religion and health 2018 Bharmal NH, McCarthy WJ, Gadgil MD, Kandula NR, Kanaya AM -
Type 2 diabetes after gestational diabetes mellitus in South Asian women in the United States.
Diabetes/metabolism research and reviews 2017 Gadgil MD, Oza-Frank R, Kandula NR, Kanaya AM -
Psychosocial Factors Associated with Subclinical Atherosclerosis in South Asians: The MASALA Study.
Journal of immigrant and minority health 2016 Shah BM, Shah S, Kandula NR, Gadgil MD, Kanaya AM -
Circulating micrornas associated with glycemic impairment and progression in Asian Indians.
Biomarker research 2015 Flowers E, Gadgil M, Aouizerat BE, Kanaya AM -
Dietary intakes among South Asian adults differ by length of residence in the USA.
Public health nutrition 2015 Talegawkar SA, Kandula NR, Gadgil MD, Desai D, Kanaya AM -
Dietary patterns are associated with metabolic risk factors in South Asians living in the United States.
The Journal of nutrition 2015 Gadgil MD, Anderson CA, Kandula NR, Kanaya AM -
Abstract P030: Traditional Cultural Beliefs and Length of Residence in the United States are Associated With Dietary Intakes Among South Asians.
Circulation 2015 Sameera A Talegawkar, Namratha R Kandula, Meghana D Gadgil, Dipika Desai, Alka M Kanaya -
Abstract P300: Circulating MicroRNAs Associated with Glycemic Impairment and Progression in Asian Indians.
Circulation 2015 Elena Flowers, Bradley E Aouizerat, Meghana Gadgil, Alka M Kanaya -
Do static and dynamic insulin resistance indices perform similarly in predicting pre-diabetes and type 2 diabetes?
Diabetes research and clinical practice 2014 Liu R, Christoffel KK, Brickman WJ, Liu X, Gadgil M, Wang G, Zimmerman D, Chen Q, Wang B, Li Z, Xing H, Xu X, Wang X -
Dietary patterns in Asian Indians in the United States: an analysis of the metabolic syndrome and atherosclerosis in South Asians Living in America study.
Journal of the Academy of Nutrition and Dietetics 2013 Gadgil MD, Anderson CAM, Kandula NR, Kanaya AM -
Laboratory testing for and diagnosis of nutritional deficiencies in pregnancy before and after bariatric surgery.
Journal of women's health (2002) 2013 Gadgil MD, Chang HY, Richards TM, Gudzune KA, Huizinga MM, Clark JM, Bennett WL -
Screening and diagnosis of micronutrient deficiencies before and after bariatric surgery.
Obesity surgery 2013 Gudzune KA, Huizinga MM, Chang HY, Asamoah V, Gadgil M, Clark JM -
Caring for Women with Pregnancy after Bariatric Surgery.
Bariatric Surgical Practice and Patient Care 2013 Meghana D. Gadgil, Wendy L. Bennett -
The effects of carbohydrate, unsaturated fat, and protein intake on measures of insulin sensitivity: results from the OmniHeart trial.
Diabetes care 2012 Gadgil MD, Appel LJ, Yeung E, Anderson CA, Sacks FM, Miller ER -
Sexual ramifications of medical illness.
Clinical obstetrics and gynecology 2009 Perez K, Gadgil M, Dizon DS