Matthew Spitzer, PhD
Associate Professor
Otolaryngology
School of Medicine

The Spitzer Lab is working to develop our understanding of how the immune system coordinates its responses across the organism with an emphasis on tumor immunology. We combine methods in experimental immunology and cancer biology with computation to understand the modes in which the immune system can respond to tumors and to rationally initiate curative immune responses against cancer.

Education & Training

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• BS Biology Georgetown University
• PhD Immunology Stanford University

Websites

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• Spitzer Lab (spitzerlab.org)

Grants and Projects

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• Quantitatively modeling immune responses to cancer, NIH, 2016-2021
• Single-cell High-dimensional Characterization of the Bone Marrow Microenvironment in Health and Disease, NIH, 2017-2019
• Revealing the tumor-immune network by mass cytometry, NIH, 2014-2018

Publications (72)

Top publication keywords:
ImmunotherapyCell CommunicationTumor MicroenvironmentSingle-Cell AnalysisFlow CytometryCD8-Positive T-LymphocytesImmune SystemMelanoma, ExperimentalProteomicsThyroiditis, SuppurativeLymphocyte ActivationPneumoniaNeoplasmsT-LymphocytesMass Spectrometry

• Author Correction: Systemic dysfunction and plasticity of the immune macroenvironment in cancer models.
  Nature medicine 2024 Allen BM, Hiam KJ, Burnett CE, Venida A, DeBarge R, Tenvooren I, Marquez DM, Cho NW, Carmi Y, Spitzer MH
• The tumor microenvironment of benign and malignant salivary gland tumors.
  Head & neck 2024 Wai KC, Okholm TLH, Ha PK, Marquez DM, Tenvooren I, Jones KB, Spitzer MH
• Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment.
  JCI insight 2024 Hatae R, Kyewalabye K, Yamamichi A, Chen T, Phyu S, Chuntova P, Nejo T, Levine LS, Spitzer MH, Okada H
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy.
  bioRxiv : the preprint server for biology 2024 Revach OY, Cicerchia AM, Shorer O, Petrova B, Anderson S, Park J, Chen L, Mehta A, Wright SJ, McNamee N, Tal-Mason A, Cattaneo G, Tiwari P, Xie H, Sweere JM, Cheng LC, Sigal N, Enrico E, Miljkovic M, …
• Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4+ naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma.
  Journal for immunotherapy of cancer 2024 Kovacsovics-Bankowski M, Sweere JM, Healy CP, Sigal N, Cheng LC, Chronister WD, Evans SA, Marsiglio J, Gibson B, Swami U, Erickson-Wayman A, McPherson JP, Derose YS, Eliason AL, Medina CO, Srinivasan …

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• A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis.
  bioRxiv : the preprint server for biology 2024 Castillo JG, DeBarge R, Mende A, Tenvooren I, Marquez DM, Straub A, Busch DH, Spitzer MH, DuPage M
• Epigenetic reprogramming shapes the cellular landscape of schwannoma.
  Nature communications 2024 Liu SJ, Casey-Clyde T, Cho NW, Swinderman J, Pekmezci M, Dougherty MC, Foster K, Chen WC, Villanueva-Meyer JE, Swaney DL, Vasudevan HN, Choudhury A, Pak J, Breshears JD, Lang UE, Eaton CD, Hiam-Galvez…
• The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation.
  eLife 2023 Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DS, Li Z, DeBarge R, Spitzer MH, Marson A, Ansel KM
• Single cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.
  bioRxiv : the preprint server for biology 2023 Karra L, Finger AM, Shechtman L, Krush M, Huang RM, Prinz M, Tennvooren I, Bahl K, Hysienaj L, Gonzalez PG, Combes AJ, Gonzalez H, Argüello RJ, Spitzer MH, Roose JP
• Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment.
  bioRxiv : the preprint server for biology 2023 Hatae R, Kyewalabye K, Yamamichi A, Chen T, Phyu S, Chuntova P, Nejo T, Levine LS, Spitzer MH, Okada H
• Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation.
  bioRxiv : the preprint server for biology 2023 Dhariwala MO, DeRogatis AM, Okoro JN, Weckel A, Tran VM, Habrylo I, Ojewumi OT, Tammen AE, Leech JM, Merana GR, Carale RO, Barrere-Cain R, Hiam-Galvez KJ, Spitzer MH, Scharschmidt TC
• Simvastatin induces human gut bacterial cell surface genes.
  Molecular microbiology 2023 Escalante V, Nayak RR, Noecker C, Babdor J, Spitzer M, Deutschbauer AM, Turnbaugh PJ
• The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation.
  bioRxiv : the preprint server for biology 2023 Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DR, Li Z, Debarge R, Spitzer MH, Marson A, Ansel KM
• Computational Methods for Single-Cell Proteomics.
  Annual review of biomedical data science 2023 Guldberg SM, Okholm TLH, McCarthy EE, Spitzer MH
• Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes.
  Cell 2023 Rahim MK, Okholm TLH, Jones KB, McCarthy EE, Liu CC, Yee JL, Tamaki SJ, Marquez DM, Tenvooren I, Wai K, Cheung A, Davidson BR, Johri V, Samad B, O'Gorman WE, Krummel MF, van Zante A, Combes AJ, Angelo…
• Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
  Science (New York, N.Y.) 2022 Allen GM, Frankel NW, Reddy NR, Bhargava HK, Yoshida MA, Stark SR, Purl M, Lee J, Yee JL, Yu W, Li AW, Garcia KC, El-Samad H, Roybal KT, Spitzer MH, Lim WA
• Innate type 2 immunity controls hair follicle commensalism by Demodex mites.
  Immunity 2022 Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, Singh K, Damsky W, Liao C, Arouge E, Tenvooren I, Marquez DM, Schroeder AW, Cohen JN, Fassett MS, Lee J, Daniel SG, Bittinger K, Díaz RE, Fraser JS, Ali N, …
• Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients.
  Immunity 2022 Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Munoz Sandoval P, Willmore A, UCSF COMET Consortium, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Calfee CS, Erle DJ…
• A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection.
  Cell reports 2022 McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Tenvooren I, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH, Rutishauser RL
• Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
  Cell 2022 Reticker-Flynn NE, Zhang W, Belk JA, Basto PA, Escalante NK, Pilarowski GOW, Bejnood A, Martins MM, Kenkel JA, Linde IL, Bagchi S, Yuan R, Chang S, Spitzer MH, Carmi Y, Cheng J, Tolentino LL, Choi O, …
• Postmitotic G1 phase survivin drives mitogen-independent cell division of B lymphocytes.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Singh A, Spitzer MH, Joy JP, Kaileh M, Qiu X, Nolan GP, Sen R
• Variation of Immune Cell Responses in Humans Reveals Sex-Specific Coordinated Signaling Across Cell Types.
  Frontiers in immunology 2022 Fragiadakis GK, Bjornson-Hooper ZB, Madhireddy D, Sachs K, Chen H, McIlwain DR, Spitzer MH, Bendall SC, Nolan GP
• Influence of Self-MHC Class I Recognition on the Dynamics of NK Cell Responses to Cytomegalovirus Infection.
  Journal of immunology (Baltimore, Md. : 1950) 2022 Potempa M, Aguilar OA, Gonzalez-Hinojosa MDR, Tenvooren I, Marquez DM, Spitzer MH, Lanier LL
• A conserved immune trajectory of recovery in hospitalized COVID-19 patients.
  bioRxiv : the preprint server for biology 2022 Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Sandoval PM, UCSF COMET Consortium, Calfee CS, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Erle DJ, Ansel KM, …
• A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates.
  Frontiers in immunology 2022 Bjornson-Hooper ZB, Fragiadakis GK, Spitzer MH, Chen H, Madhireddy D, Hu K, Lundsten K, McIlwain DR, Nolan GP
• Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Ishiyama K, Arakawa-Hoyt J, Aguilar OA, Damm I, Towfighi P, Sigdel T, Tamaki S, Babdor J, Spitzer MH, Reed EF, Sarwal MM, Lanier LL, CMV Systems Immunobiology Group
• Cellular architecture of human brain metastases.
  Cell 2022 Gonzalez H, Mei W, Robles I, Hagerling C, Allen BM, Hauge Okholm TL, Nanjaraj A, Verbeek T, Kalavacherla S, van Gogh M, Georgiou S, Daras M, Phillips JJ, Spitzer MH, Roose JP, Werb Z
• Archetypes of checkpoint-responsive immunity.
  Trends in immunology 2021 Im K, Combes AJ, Spitzer MH, Satpathy AT, Krummel MF
• The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes.
  JCI insight 2021 Dong S, Hiam-Galvez KJ, Mowery CT, Herold KC, Gitelman SE, Esensten JH, Liu W, Lares AP, Leinbach AS, Lee M, Nguyen V, Tamaki SJ, Tamaki W, Tamaki CM, Mehdizadeh M, Putnam AL, Spitzer MH, Ye CJ, Tang …
• SCITO-seq: single-cell combinatorial indexed cytometry sequencing.
  Nature methods 2021 Hwang B, Lee DS, Tamaki W, Sun Y, Ogorodnikov A, Hartoularos GC, Winters A, Yeung BZ, Nazor KL, Song YS, Chow ED, Spitzer MH, Ye CJ
• Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
  Journal for immunotherapy of cancer 2021 Sinha M, Zhang L, Subudhi S, Chen B, Marquez J, Liu EV, Allaire K, Cheung A, Ng S, Nguyen C, Friedlander TW, Aggarwal R, Spitzer M, Allison JP, Small EJ, Sharma P, Fong L
• Systemic immunity in cancer.
  Nature reviews. Cancer 2021 Hiam-Galvez KJ, Allen BM, Spitzer MH
• Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response.
  Immunity 2021 Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH
• Landscape of coordinated immune responses to H1N1 challenge in humans.
  The Journal of clinical investigation 2020 Rahil Z, Leylek R, Schürch CM, Chen H, Bjornson-Hooper Z, Christensen SR, Gherardini PF, Bhate SS, Spitzer MH, Fragiadakis GK, Mukherjee N, Kim N, Jiang S, Yo J, Gaudilliere B, Affrime M, Bock B, …
• Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.
  Nature immunology 2020 Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, Gate RE, Tang Q, Bluestone JA, Spitzer MH, Ye CJ,…
• ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network.
  BMC bioinformatics 2020 Atallah MB, Tandon V, Hiam KJ, Boyce H, Hori M, Atallah W, Spitzer MH, Engleman E, Mallick P
• Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer.
  Cell 2020 Oh DY, Kwek SS, Raju SS, Li T, McCarthy E, Chow E, Aran D, Ilano A, Pai CS, Rancan C, Allaire K, Burra A, Sun Y, Spitzer MH, Mangul S, Porten S, Meng MV, Friedlander TW, Ye CJ, Fong L
• Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.
  Annals of surgical oncology 2020 Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI
• Systemic dysfunction and plasticity of the immune macroenvironment in cancer models.
  Nature medicine 2020 Allen BM, Hiam KJ, Burnett CE, Venida A, DeBarge R, Tenvooren I, Marquez DM, Cho NW, Carmi Y, Spitzer MH
• Depletion of microbiome-derived molecules in the host using Clostridium genetics.
  Science (New York, N.Y.) 2019 Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA
• Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
  Nature immunology 2019 Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, …
• De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.
  Nature biotechnology 2019 Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, …
• Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy.
  Cell reports 2019 Hartmann FJ, Babdor J, Gherardini PF, Amir ED, Jones K, Sahaf B, Marquez DM, Krutzik P, O'Donnell E, Sigal N, Maecker HT, Meyer E, Spitzer MH, Bendall SC
• Hacking the 'Cellular Immunology Agency': T cells caught in the act.
  Nature immunology 2019 Spitzer MH
• Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis.
  Methods in molecular biology (Clifton, N.J.) 2019 Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC
• Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment.
  Cancer immunology research 2018 Gonzalez-Junca A, Driscoll KE, Pellicciotta I, Du S, Lo CH, Roy R, Parry R, Tenvooren I, Marquez DM, Spitzer MH, Barcellos-Hoff MH
• Metal-isotope-tagged monoclonal antibodies for high-dimensional mass cytometry.
  Nature protocols 2018 Han G, Spitzer MH, Bendall SC, Fantl WJ, Nolan GP
• MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data.
  Cell reports 2018 Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, Butte AJ
• Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System.
  Cell reports 2018 Avanzi MP, Yeku O, Li X, Wijewarnasuriya DP, van Leeuwen DG, Cheung K, Park H, Purdon TJ, Daniyan AF, Spitzer MH, Brentjens RJ
• Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.
  Cell stem cell 2018 Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL
• A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites.
  Nature 2017 Dodd D, Spitzer MH, Van Treuren W, Merrill BD, Hryckowian AJ, Higginbottom SK, Le A, Cowan TM, Nolan GP, Fischbach MA, Sonnenburg JL
• Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.
  Cell stem cell 2017 Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL
• Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells.
  Cell reports 2017 Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR
• Systemic Immunity Is Required for Effective Cancer Immunotherapy.
  Cell 2017 Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG
• Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
  Nature medicine 2017 Furman D, Chang J, Lartigue L, Bolen CR, Haddad F, Gaudilliere B, Ganio EA, Fragiadakis GK, Spitzer MH, Douchet I, Daburon S, Moreau JF, Nolan GP, Blanco P, Déchanet-Merville J, Dekker CL, Jojic V, …
• Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
  JCI insight 2016 Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG
• Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy.
  Journal of immunology (Baltimore, Md. : 1950) 2016 Fragiadakis GK, Baca QJ, Gherardini PF, Ganio EA, Gaudilliere DK, Tingle M, Lancero HL, McNeil LS, Spitzer MH, Wong RJ, Shaw GM, Darmstadt GL, Sylvester KG, Winn VD, Carvalho B, Lewis DB, Stevenson DK…
• Automated mapping of phenotype space with single-cell data.
  Nature methods 2016 Samusik N, Good Z, Spitzer MH, Davis KL, Nolan GP
• Mass Cytometry: Single Cells, Many Features.
  Cell 2016 Spitzer MH, Nolan GP
• Metabolite profiles of rats in repeated dose toxicological studies after oral and inhalative exposure.
  Toxicology letters 2016 Fabian E, Bordag N, Herold M, Kamp H, Krennrich G, Looser R, Ma-Hock L, Mellert W, Montoya G, Peter E, Prokudin A, Spitzer M, Strauss V, Walk T, Zbranek R, van Ravenzwaay B
• IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system.
  Science (New York, N.Y.) 2015 Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP
• Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
  Nature 2015 Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG
• Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm.
  Nature protocols 2015 Zunder ER, Finck R, Behbehani GK, Amir el-AD, Krishnaswamy S, Gonzalez VD, Lorang CG, Bjornson Z, Spitzer MH, Bodenmiller B, Fantl WJ, Pe'er D, Nolan GP
• Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C
• Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.
  Science (New York, N.Y.) 2014 Krishnaswamy S, Spitzer MH, Mingueneau M, Bendall SC, Litvin O, Stone E, Pe'er D, Nolan GP
• A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Megill A, Lee T, DiBattista AM, Song JM, Spitzer MH, Rubinshtein M, Habib LK, Capule CC, Mayer M, Turner RS, Kirkwood A, Yang J, Pak DT, Lee HK, Hoe HS
• The transcriptional landscape of αβ T cell differentiation.
  Nature immunology 2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Immunological Genome Consortium, Best AJ, Knell J, …
• Risks and benefits of testosterone therapy in older men.
  Nature reviews. Endocrinology 2013 Spitzer M, Huang G, Basaria S, Travison TG, Bhasin S
• Thyrotoxicosis with post-treatment hypothyroidism in a patient with acute suppurative thyroiditis due to porphyromonas.
  Thyroid : official journal of the American Thyroid Association 2011 Spitzer M, Alexanian S, Farwell AP
• ApoE receptor 2 regulates synapse and dendritic spine formation.
  PloS one 2011 Dumanis SB, Cha HJ, Song JM, Trotter JH, Spitzer M, Lee JY, Weeber EJ, Turner RS, Pak DT, Rebeck GW, Hoe HS
• Left lateralized P300 amplitude deficit in schizophrenic patients depends on pitch disparity.
  Biological psychiatry 1997 Weisbrod M, Winkler S, Maier S, Hill H, Thomas C, Spitzer M
• [Significance of historical and current hallucinogenic research in psychiatry].
  Der Nervenarzt 1993 Hermle L, Gouzoulis E, Oepen G, Spitzer M, Kovar KA, Borchardt D, Fünfgeld M, Berger M