Matthew Spinelli, MD, MAS
Assistant Professor
Medicine
School of Medicine

I am HIV/ID physician with training in implementation science methods who uses these approaches to support pre-exposure prophylaxis (PrEP) implementation, PrEP/HIV ART adherence, and PrEP persistence/HIV retention in care. A key tool we are using in this work is a point-of-care urine tenofovir test that can provide real-time adherence information to clinicians to drive adherence interventions.

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More recently, I lead projects on development of adherence measurement techniques for doxycycline post-exposure prophylaxis, including a directly observed therapy randomized trial. In terms of educational initiatives, I am the co-director of the Implementation Science Short Course and the Individual-Level Intervention Design course in the UCSF Department of Epidemiology. As an HIV/ID clinician, I serve as the PrEP Medical Lead for the Ward 86 Clinic. Finally, I am a member of the Partnership for Research in Implementation Science for Equity, a collaboration between the SF Department of Public Health and UCSF that seeks to use implementation science methods to advance health equity.

Education & Training

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• B.A. Italian Literature Columbia University
• M.D. Medicine Mount Sinai School of Medicine
• M.A.S. Epidemiology & Implementation Science University of California, San Francisco
• Fellowship HIV Clinical and Research Fellowship University of California, San Francisco
• Fellowship Infectious Diseases University of California, San Francisco
• Residency Internal Medicine University of California, San Francisco

Websites

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• Posts on X MattSpinelliMD (X.com)

Grants and Projects

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• Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP, NIH, 2024-2029
• Developing a U.S. National Cohort to Improve Virologic Suppression among Stimulant-using Men Living with HIV, NIH, 2023-2025
• PrEP Point-of-Care Brief-Intervention for Adherence among Young Men Who Have Sex with Men (PrEP2-BAY Study), NIH, 2020-2024
• Evaluation of the Interplay between HIV and COVID-19 in a large urban safety-net HIV clinic, NIH, 2020-2024
• Evaluation of the Impact of HIV Status on the Immune Response to mRNA COVID-19 Vaccines, NIH, 2022-2024
• UCSF-Gladstone Center for AIDS Research, NIH, 1988-2022

Publications (90)

Top publication keywords:
Communicable Disease ControlEmtricitabineSeroconversionAlanineTenofovirPre-Exposure ProphylaxisPyridonesDoxycyclineHIV InfectionsPoint-of-Care TestingAnti-HIV AgentsAdenineDiketopiperazinesHIV Integrase InhibitorsMedication Adherence

• Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women.
  The New England journal of medicine 2023 Stewart J, Oware K, Donnell D, Violette LR, Odoyo J, Soge OO, Scoville CW, Omollo V, Mogaka FO, Sesay FA, McClelland RS, Spinelli M, Gandhi M, Bukusi EA, Baeten JM, dPEP Kenya Study Team
• Efficacy and safety of long-acting cabotegravir compared with daily oral tenofovir disoproxil fumarate plus emtricitabine to prevent HIV infection in cisgender men and transgender women who have sex with men 1 year after study unblinding: a secondary analysis of the phase 2b and 3 HPTN 083 randomised controlled trial.
  The lancet. HIV 2023 Landovitz RJ, Hanscom BS, Clement ME, Tran HV, Kallas EG, Magnus M, Sued O, Sanchez J, Scott H, Eron JJ, Del Rio C, Fields SD, Marzinke MA, Eshleman SH, Donnell D, Spinelli MA, Kofron RM, Berman R, …
• Addressing the Sexually Transmitted Infection and HIV Syndemic.
  JAMA 2019 Gandhi M, Spinelli MA, Mayer KH
• Unintentional Fentanyl Use Detected in Hair of People With HIV Risk Using Methamphetamine.
  JAMA 2025 Appa A, Spinelli MA, Javanbakht M, Heise MJ, Okochi H, Bazazi AR, Coffin P, Gorbach PM, Gandhi M
• Reply.
  Journal of acquired immune deficiency syndromes (1999) 2025 Spinelli MA, Christopoulos KA

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• The impact of adherence counseling incorporating a point of care urine tenofovir assay on virologic suppression among individuals failing tenofovir-lamivudine-dolutegravir: A pre-post intervention study.
  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2024 Bikinesi L, Spinelli MA, Nyoni N, Mouton D, Mengistu A, Kamangu J, Konstantinus I, Kalimugogo P, Mutandi G, Negussie F, Wang G, Welty S, McFarland W, Beard RS, Haberer J, McCluskey S, Gandhi M, Hong …
• Preexposure Prophylaxis (PrEP) for HIV.
  JAMA 2024 Spinelli MA, Ngure K, Gandhi M
• High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Spinelli MA, Bisom-Rapp E, Heise MJ, Camp C, Appa A, Liu AY, Sassaman K, Shiels M, Mayorga-Munoz F, Chimezie A, Nguyen J, Oskarsson J, Gandhi M
• Prevalence and Correlates of SARS-CoV-2 Vaccine Uptake and Hesitancy Among People With HIV Across the United States.
  Journal of acquired immune deficiency syndromes (1999) 2024 Spinelli MA, Johnson MO, Lisha NE, Jain JP, Moreira CV, Glidden DV, Burkholder GA, Crane HM, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Gandhi M, Christopoulos KA
• Impact of the Coronavirus Disease 2019 Pandemic on Substance Use Disorder Risk Among People Living With Human Immunodeficiency Virus (HIV) Enrolled in HIV Care in the United States: An Interrupted Time Series Analysis.
  Open forum infectious diseases 2024 Jain JP, Heise MJ, Lisha NE, Moreira CH, Glidden DV, Burkholder GA, Crane HM, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Dawson-Rose C, Johnson MO, Christopoulos KA, Gandhi M, Spinelli …
• Factors Associated with Usage of Oral-PrEP among Female Sex Workers in Nairobi, Kenya, Assessed by Self-Report and a Point-of-Care Urine Tenofovir Immunoassay.
  AIDS and behavior 2024 Shah P, Spinelli M, Irungu E, Kabuti R, Ngurukiri P, Babu H, Kungu M, Champions TMFS, Nyabuto C, Mahero A, Devries K, Kyegombe N, Medley GF, Gafos M, Seeley J, Weiss HA, Kaul R, Gandhi M, Beattie TS, …
• Impact of a point-of-care urine tenofovir assay on adherence to HIV pre-exposure prophylaxis among women in Kenya: a randomised pilot trial.
  The lancet. HIV 2024 Gandhi M, Glidden DV, Chakravarty D, Wang G, Biwott C, Mogere P, Maina G, Njeru I, Kiptinness C, Okello P, Spinelli MA, Chatterjee P, Velloza J, Ogello V, Medina-Marino A, Okochi H, Mugo NR, Ngure K
• Identifying Implementation Determinants and Strategies for Long-Acting Injectable Cabotegravir-Rilpivirine in People With HIV Who Are Virally Unsuppressed.
  Journal of acquired immune deficiency syndromes (1999) 2024 Hickey MD, Grochowski J, Mayorga-Munoz F, Oskarsson J, Imbert E, Spinelli M, Szumowski JD, Appa A, Koester K, Dauria EF, McNulty M, Colasanti J, Havlir DV, Gandhi M, Christopoulos KA
• Point-of-care urine tenofovir test predicts future HIV preexposure prophylaxis discontinuation among young users.
  AIDS (London, England) 2024 Martinson T, Montoya R, Moreira C, Kuncze K, Sassaman K, Heise MJ, Glidden DV, Amico KR, Arnold EA, Buchbinder SP, Ewart LD, Carrico A, Wang G, Okochi H, Scott HM, Gandhi M, Spinelli MA
• Viral Suppression Trajectories Destabilized After Coronavirus Disease 2019 Among US People With Human Immunodeficiency Virus: An Interrupted Time Series Analysis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Spinelli MA, Christopoulos KA, Moreira CV, Jain JP, Lisha N, Glidden DV, Burkholder GA, Crane HM, Shapiro AE, Jacobson JM, Cachay ER, Mayer KH, Napravnik S, Moore RD, Gandhi M, Johnson MO
• Plasma-based antigen persistence in the post-acute phase of COVID-19.
  The Lancet. Infectious diseases 2024 Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Chang Song C, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli …
• Low-cost urine tenofovir assay to triage dolutegravir resistance testing.
  The lancet. HIV 2024 Martinson T, Nwogu-Attah J, Spinelli M, Gandhi M
• Point-of-care urine tenofovir monitoring of adherence to drive interventions for HIV treatment and prevention.
  Expert review of molecular diagnostics 2024 Spinelli M, Gandhi M
• Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection.
  medRxiv : the preprint server for health sciences 2023 Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Song CC, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, …
• Adherence determination using urine-tenofovir point-of-care testing and pharmacy refill records: A cross-sectional study.
  Medicine 2023 Herbertson EC, Lahiri CD, Olugbake OA, Soremekun RO, Spinelli MA, Gandhi M
• Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV.
  Journal of the American Heart Association 2023 Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY
• Urine point-of-care tenofovir test demonstrates strong predictive clinical and research utility.
  AIDS (London, England) 2023 Mustanski B, Ryan DT, Spinelli MA, Gandhi M, Newcomb ME
• Pandemic expertise: qualitative findings on the experiences of living with HIV during the COVID-19 pandemic.
  AIDS care 2023 Mars SG, Spinelli MA, Ondocsin J, Koester KA, Rodriguez ES, Jain J, Arreguin M, Johnson MO, Gandhi M
• Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV.
  medRxiv : the preprint server for health sciences 2023 Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY
• The intertwined epidemics of HIV and COVID-19 - emerging data and responses.
  Current opinion in HIV and AIDS 2023 Spinelli M, Gandhi M, Riva A
• Urine Tenofovir Levels Strongly Correlate With Virologic Suppression in Patients With Human Immunodeficiency Virus on Tenofovir Alafenamide-Based Antiretroviral Therapy.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023 Johnson KA, Okochi H, Arreguin M, Watabe J, Glidden DV, Chattopadhyay A, Imbert E, Hickey MD, Gandhi M, Spinelli M
• Point-of-care urine tenofovir testing to predict HIV drug resistance among individuals with virologic failure.
  AIDS (London, England) 2023 McCluskey SM, Govender K, Adamson J, Gandhi M, Spinelli MA, Moosa MY, Muyindike W, Moodley P, Pillay M, Masette G, Sunpath H, Pillay S, Chen G, Hedt-Gauthier B, Marconi VC, Siedner MJ
• Chronic viral coinfections differentially affect the likelihood of developing long COVID.
  The Journal of clinical investigation 2023 Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, …
• Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Spinelli MA, Peluso MJ, Lynch KL, Yun C, Glidden DV, Henrich TJ, Deeks SG, Gandhi M
• Impact of Multicomponent Support Strategies on Human Immunodeficiency Virus Virologic Suppression Rates During Coronavirus Disease 2019: An Interrupted Time Series Analysis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Spinelli MA, Le Tourneau N, Glidden DV, Hsu L, Hickey MD, Imbert E, Arreguin M, Jain JP, Oskarsson JJ, Buchbinder SP, Johnson MO, Havlir D, Christopoulos KA, Gandhi M
• Urine tenofovir-monitoring predicts HIV viremia in patients treated with high genetic-barrier regimens.
  AIDS (London, England) 2022 van Zyl G, Jennings L, Kellermann T, Nkantsu Z, Cogill D, van Schalkwyk M, Spinelli M, Decloedt E, Orrell C, Gandhi M
• COVID-19 Outcomes and Risk Factors Among People Living with HIV.
  Current HIV/AIDS reports 2022 Spinelli MA, Jones BLH, Gandhi M
• Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID.
  medRxiv : the preprint server for health sciences 2022 Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, …
• Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection.
  AIDS (London, England) 2022 Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, …
• Relationship Dynamics are Associated with Self-Reported Adherence but not an Objective Adherence Measure in Malawi.
  AIDS and behavior 2022 Conroy AA, McKenna S, Ruark A, Neilands TB, Spinelli M, Gandhi M
• Promises and challenges: cabotegravir for preexposure prophylaxis.
  Current opinion in HIV and AIDS 2022 Spinelli MA, Grinsztejn B, Landovitz RJ
• Drug Resistance, Rather than Low Tenofovir Levels in Blood or Urine, Is Associated with Tenofovir, Emtricitabine, and Efavirenz Failure in Resource-Limited Settings.
  AIDS research and human retroviruses 2021 Jennings L, Kellermann T, Spinelli M, Nkantsu Z, Cogill D, van Schalkwyk M, Decloedt E, van Zyl G, Orrell C, Gandhi M
• Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement.
  Open forum infectious diseases 2021 Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, …
• Characterizing the COVID-19 Illness Experience to Inform the Study of Post-acute Sequelae and Recovery.
  International journal of behavioral medicine 2021 Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA
• LB8. Lower SARS-CoV-2 IgG and Pseudovirus Neutralization Titers Post-mRNA Vaccination among People Living with HIV.
  Open Forum Infectious Diseases 2021 Matthew A Spinelli, Michael J Peluso, Kara Lynch, Cassandra Yun, David V Glidden, Timothy J Henrich, Steve Deeks, Monica Gandhi
• SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV.
  AIDS (London, England) 2021 Spinelli MA, Brown LB, Glidden DV, Hunter K, Martin-Tuite P, Zheng J, Sera C, Havlir D, Buchbinder SP, Gandhi M
• SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV.
  AIDS 2021 Matthew A. Spinelli, Lillian B. Brown, David V. Glidden, Kyle Hunter, Patrick Martin-Tuite, James Zheng, Curtis Sera, Diane Havlir, Susan P. Buchbinder, Monica Gandhi
• Brief Report: No Difference in Urine Tenofovir Levels in Patients Living With HIV on Unboosted Versus Dose-Adjusted Boosted Tenofovir Alafenamide.
  Journal of acquired immune deficiency syndromes (1999) 2021 Johnson KA, Okochi H, Glidden DV, Gandhi M, Spinelli M
• Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms.
  Cell reports 2021 Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L,…
• Effectiveness of Adding a Mask Recommendation to Other Public Health Measures.
  Annals of internal medicine 2021 Spinelli MA, Glidden DV, Gennatas ED, Rutherford GW, Gandhi M
• SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.
  Science advances 2021 Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, …
• Tenofovir-based PrEP for COVID-19: an untapped opportunity?
  AIDS (London, England) 2021 DeJong C, Spinelli MA, Okochi H, Gandhi M
• SARS-CoV-2 vaccination in people with HIV.
  The lancet. HIV 2021 Spinelli MA
• Use of Drug-level Testing and Single-genome Sequencing to Unravel a Case of Human Immunodeficiency Virus Seroconversion on Pre-exposure Prophylaxis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Spinelli MA, Lowery B, Shuford JA, Spindler J, Kearney MF, McFarlane JR, McDonald C, Okochi H, Phung N, Kuncze K, Jee K, Johannessen D, Anderson PL, Smith DK, Defechereux P, Grant RM, Gandhi M
• SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study.
  The lancet. HIV 2021 Spinelli MA, Lynch KL, Yun C, Glidden DV, Peluso MJ, Henrich TJ, Gandhi M, Brown LB
• Lower Urine Tenofovir Concentrations Among Individuals Taking Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate: Implications for Point-of-Care Testing.
  Open forum infectious diseases 2021 Johnson KA, Niu X, Glidden DV, Castillo-Mancilla JR, Yager J, MaWhinney S, Morrow M, Okochi H, Cressey TR, Drain PK, Gandhi M, Anderson PL, Spinelli MA
• Lowering SARS-CoV-2 viral load might affect transmission but not disease severity in secondary cases - Authors' reply.
  The Lancet. Infectious diseases 2021 Spinelli MA, Rutherford G, Gandhi M
• Tenofovir and emtricitabine concentrations in hair are comparable between individuals on tenofovir disoproxil fumarate versus tenofovir alafenamide-based ART.
  Drug testing and analysis 2021 Okochi H, Louie A, Phung N, Zhang K, Tallerico RM, Kuncze K, Spinelli MA, Koss CA, Benet LZ, Gandhi M
• Characterizing the COVID-19 illness experience to inform the study of post-acute sequelae and recovery: a qualitative study.
  medRxiv : the preprint server for health sciences 2021 Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA
• Disparities in Integrase Inhibitor Usage in the Modern HIV Treatment Era: A Population-Based Study in a US City.
  Open forum infectious diseases 2021 Spinelli MA, Hessol NA, Schwarcz SK, Scheer S, Gandhi M, Chin Hsu L
• Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19.
  medRxiv : the preprint server for health sciences 2021 Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, …
• SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.
  medRxiv : the preprint server for health sciences 2021 Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, …
• Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19.
  medRxiv : the preprint server for health sciences 2021 Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, …
• Importance of non-pharmaceutical interventions in lowering the viral inoculum to reduce susceptibility to infection by SARS-CoV-2 and potentially disease severity.
  The Lancet. Infectious diseases 2021 Spinelli MA, Glidden DV, Gennatas ED, Bielecki M, Beyrer C, Rutherford G, Chambers H, Goosby E, Gandhi M
• Sensitivity and Specificity of the National Death Index for Multiple Causes of Death in People With HIV.
  Public health reports (Washington, D.C. : 1974) 2021 Schwarcz S, Hessol NA, Spinelli MA, Hsu LC, Wlodarczyk D, Tulsky J, Newman MD, Buchbinder SP
• Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Stalter RM, Baeten JM, Donnell D, Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Mugo N, Mujugira A, Marzinke M, Hendrix C, Gandhi M, Partners PrEP Study Team
• The interplay between HIV and COVID-19: summary of the data and responses to date.
  Current opinion in HIV and AIDS 2021 Brown LB, Spinelli MA, Gandhi M
• Pragmatic randomized trial of a pre-visit intervention to improve the quality of telemedicine visits for vulnerable patients living with HIV.
  Journal of telemedicine and telecare 2020 Hickey MD, Sergi F, Zhang K, Spinelli MA, Black D, Sola C, Blaz V, Nguyen JQ, Oskarsson J, Gandhi M, Havlir DV
• Viral suppression rates in a safety-net HIV clinic in San Francisco destabilized during COVID-19.
  AIDS (London, England) 2020 Spinelli MA, Hickey MD, Glidden DV, Nguyen JQ, Oskarsson JJ, Havlir D, Gandhi M
• Understanding PrEP Persistence: Provider and Patient Perspectives.
  AIDS and behavior 2020 Laborde ND, Kinley PM, Spinelli M, Vittinghoff E, Whitacre R, Scott HM, Buchbinder SP
• Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions.
  Current HIV/AIDS reports 2020 Spinelli MA, Haberer JE, Chai PR, Castillo-Mancilla J, Anderson PL, Gandhi M
• The importance of PrEP persistence in preventing HIV infections on PrEP.
  Journal of the International AIDS Society 2020 Spinelli MA, Laborde N, Kinley P, Whitacre R, Scott HM, Walker N, Liu AY, Gandhi M, Buchbinder SP
• Pre-exposure Prophylaxis Persistence Is a Critical Issue in PrEP Implementation.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Spinelli MA, Buchbinder SP
• Urine Tenofovir Levels Measured by a Novel Immunoassay Predict HIV Protection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Stalter RM, Baeten JM, Donnell D, Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Mugo N, Mujugira A, Marzinke M, Hendrix C, Gandhi M, Partners PrEP Study Team
• Brief Report: High Accuracy of a Real-Time Urine Antibody-Based Tenofovir Point-of-Care Test Compared With Laboratory-Based ELISA in Diverse Populations.
  Journal of acquired immune deficiency syndromes (1999) 2020 Spinelli MA, Rodrigues WC, Wang G, Vincent M, Glidden DV, Okochi H, Stalter R, Defechereux P, Deutsch M, Grant RM, Ngure K, Mugo NR, Baeten JM, Gandhi M, Partners PrEP Study Team
• Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to Preexposure Prophylaxis in Kenya (PUMA): Protocol for a Pilot Randomized Controlled Trial.
  JMIR research protocols 2020 Drain P, Ngure K, Mugo N, Spinelli M, Chatterjee P, Bacchetti P, Glidden D, Baeten J, Gandhi M
• Missed opportunities to prevent HIV infections among pre-exposure prophylaxis users: a population-based mixed methods study, San Francisco, United States.
  Journal of the International AIDS Society 2020 Spinelli MA, Laborde N, Kinley P, Whitacre R, Scott HM, Walker N, Liu AY, Gandhi M, Buchbinder SP
• Development and validation of the first point-of-care assay to objectively monitor adherence to HIV treatment and prevention in real-time in routine settings.
  AIDS (London, England) 2020 Gandhi M, Wang G, King R, Rodrigues WC, Vincent M, Glidden DV, Cressey TR, Bacchetti P, Spinelli MA, Okochi H, Siriprakaisil O, Klinbuayaem V, Mugo NR, Ngure K, Drain PK, Baeten JM
• Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics.
  AIDS (London, England) 2019 Scott HM, Spinelli M, Vittinghoff E, Morehead-Gee A, Hirozawa A, James C, Hammer H, Liu A, Gandhi M, Buchbinder S
• Homelessness at diagnosis is associated with death among people with HIV in a population-based study of a US city.
  AIDS (London, England) 2019 Spinelli MA, Hessol NA, Schwarcz S, Hsu L, Parisi MK, Pipkin S, Scheer S, Havlir D, Buchbinder SP
• Impact of Estimated Pre-Exposure Prophylaxis (PrEP) Adherence Patterns on Bone Mineral Density in a Large PrEP Demonstration Project.
  AIDS research and human retroviruses 2019 Spinelli MA, Glidden DV, Anderson PL, Gandhi M, McMahan VM, Defechereux P, Schechter M, Veloso VG, Chariyalertsak S, Guanira JV, Bekker LG, Buchbinder SP, Grant RM
• Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to PrEP in Kenya (the PUMA study): A Pilot Randomized Clinical Trial (Preprint).
  JMIR Research Protocols 2019 Paul Drain, Kenneth Ngure, Nelly Mugo, Matthew Spinelli, Purba Chatterjee, Peter Bacchetti, David Glidden, Jared Baeten, Monica Gandhi
• Brief Report: Short-Term Adherence Marker to PrEP Predicts Future Nonretention in a Large PrEP Demo Project: Implications for Point-of-Care Adherence Testing.
  Journal of acquired immune deficiency syndromes (1999) 2019 Spinelli MA, Glidden DV, Anderson PL, Gandhi M, Cohen S, Vittinghoff E, Coleman ME, Scott H, Bacon O, Elion R, Kolber MA, Buchbinder SP, Liu AY
• Brief Report: Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cutoff for a Point-of-Care Test.
  Journal of acquired immune deficiency syndromes (1999) 2019 Gandhi M, Bacchetti P, Spinelli MA, Okochi H, Baeten JM, Siriprakaisil O, Klinbuayaem V, Rodrigues WC, Wang G, Vincent M, Cressey TR, Drain PK
• High Interest in Doxycycline for Sexually Transmitted Infection Postexposure Prophylaxis in a Multicity Survey of Men Who Have Sex With Men Using a Social Networking Application.
  Sexually transmitted diseases 2019 Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Coleman K, Buchbinder SP
• Low tenofovir level in urine by a novel immunoassay is associated with seroconversion in a preexposure prophylaxis demonstration project.
  AIDS (London, England) 2019 Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Okochi H, Kuncze K, Mehrotra M, Defechereux P, Buchbinder SP, Grant RM, Gandhi M
• Missed Visits Associated With Future Preexposure Prophylaxis (PrEP) Discontinuation Among PrEP Users in a Municipal Primary Care Health Network.
  Open forum infectious diseases 2019 Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Gonzalez R, Morehead-Gee A, Gandhi M, Buchbinder SP
• 2272. High Interest in Doxycycline for Sexually Transmitted Infection Post-Exposure Prophylaxis (Doxy-PEP) in a Multi-city Survey of Men Having Sex With Men (MSM) Using a Social-Networking App.
  Open Forum Infectious Diseases 2018 Matthew A Spinelli, Hyman Scott, Eric Vittinghoff, Albert Y Liu, Kenneth Coleman, Monica Gandhi, Susan P Buchbinder
• Brief Report: A Panel Management and Patient Navigation Intervention Is Associated With Earlier PrEP Initiation in a Safety-Net Primary Care Health System.
  Journal of acquired immune deficiency syndromes (1999) 2018 Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Gandhi M, Buchbinder SP
• Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence.
  EClinicalMedicine 2018 Gandhi M, Bacchetti P, Rodrigues WC, Spinelli M, Koss CA, Drain PK, Baeten JM, Mugo NR, Ngure K, Benet LZ, Okochi H, Wang G, Vincent M
• Provider Adherence to Pre-exposure Prophylaxis Monitoring Guidelines in a Large Primary Care Network.
  Open forum infectious diseases 2018 Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Buchbinder SP
• Food Insecurity is Associated with Poor HIV Outcomes Among Women in the United States.
  AIDS and behavior 2017 Spinelli MA, Frongillo EA, Sheira LA, Palar K, Tien PC, Wilson T, Merenstein D, Cohen M, Adedimeji A, Wentz E, Adimora AA, Metsch LR, Turan JM, Kushel MB, Weiser SD
• Factors associated with substance use in older homeless adults: Results from the HOPE HOME study.
  Substance abuse 2016 Spinelli MA, Ponath C, Tieu L, Hurstak EE, Guzman D, Kushel M
• Common tasks in microscopic and ultrastructural image analysis using ImageJ.
  Ultrastructural pathology 2007 Papadopulos F, Spinelli M, Valente S, Foroni L, Orrico C, Alviano F, Pasquinelli G
• Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses.
  Journal of virology 2007 Chen P, Hübner W, Spinelli MA, Chen BK