Matthew Spinelli, MD, MAS
Associate Professor
Medicine
School of Medicine

415-806-8554

I am HIV/ID physician with training in implementation science methods who uses these approaches to support pre-exposure prophylaxis (PrEP) implementation, PrEP/HIV ART adherence, and PrEP persistence/HIV retention in care. A key tool we are using in this work is a point-of-care urine tenofovir test that can provide real-time adherence information to clinicians to drive adherence interventions.

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More recently, I lead projects on development of adherence measurement techniques for doxycycline post-exposure prophylaxis, including a directly observed therapy randomized trial. In terms of educational initiatives, I am the co-director of the Implementation Science Short Course and the Individual-Level Intervention Design course in the UCSF Department of Epidemiology. As an HIV/ID clinician, I serve as the PrEP Medical Lead for the Ward 86 Clinic. Finally, I am a member of the Partnership for Research in Implementation Science for Equity, a collaboration between the SF Department of Public Health and UCSF that seeks to use implementation science methods to advance health equity.

Education & Training

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  • B.A. Italian Literature Columbia University
  • M.D. Medicine Mount Sinai School of Medicine
  • M.A.S. Epidemiology & Implementation Science University of California, San Francisco
  • Fellowship HIV Clinical and Research Fellowship University of California, San Francisco
  • Fellowship Infectious Diseases University of California, San Francisco
  • Residency Internal Medicine University of California, San Francisco

Websites

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Grants and Projects

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Publications (99)

Top publication keywords:
Communicable Disease ControlEmtricitabineMobile ApplicationsPost-Exposure ProphylaxisSexually Transmitted Diseases, BacterialHomosexuality, MaleTenofovirPre-Exposure ProphylaxisSustained Virologic ResponseDoxycyclineHIV InfectionsViral LoadPoint-of-Care TestingAnti-HIV AgentsMedication Adherence

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