Matthew Lohse, PhD
Staff Research Associate IV
Microbiology and Immunology
School of Medicine
Education & Training
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- Ph.D. Graduate Division (Biochemistry) University of California, San Francisco 2010
Publications (30)
Top publication keywords:
DNA, FungalFarnesolChromatin ImmunoprecipitationFungal ProteinsDNA-Binding ProteinsMicrobial InteractionsGenes, Mating Type, FungalClioquinolGenes, SwitchAspartic Acid ProteasesAntifungal AgentsBiofilmsCandida albicansGene Expression Regulation, FungalCandidiasis
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Variation in transcription regulator expression underlies differences in white-opaque switching between the SC5314 reference strain and the majority of Candida albicans clinical isolates.
Genetics 2023 Lohse MB, Ziv N, Johnson AD -
Broad susceptibility of Candida auris strains to 8-hydroxyquinolines and mechanisms of resistance.
mBio 2023 Lohse MB, Laurie MT, Levan S, Ziv N, Ennis CL, Nobile CJ, DeRisi J, Johnson AD -
Broad sensitivity of Candida auris strains to quinolones and mechanisms of resistance.
bioRxiv : the preprint server for biology 2023 Lohse MB, Laurie MT, Levan S, Ziv N, Ennis CL, Nobile CJ, DeRisi J, Johnson AD -
Farnesol and phosphorylation of the transcriptional regulator Efg1 affect Candida albicans white-opaque switching rates.
PloS one 2023 Brenes LR, Johnson AD, Lohse MB -
A Screen for Small Molecules to Target Candida albicans Biofilms.
Journal of fungi (Basel, Switzerland) 2020 Lohse MB, Ennis CL, Hartooni N, Johnson AD, Nobile CJ
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An Opaque Cell-Specific Expression Program of Secreted Proteases and Transporters Allows Cell-Type Cooperation in Candida albicans.
Genetics 2020 Lohse MB, Brenes LR, Ziv N, Winter MB, Craik CS, Johnson AD -
A Set of Diverse Genes Influence the Frequency of White-Opaque Switching in Candida albicans.
G3 (Bethesda, Md.) 2020 Brenes LR, Lohse MB, Hartooni N, Johnson AD -
Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms.
Frontiers in microbiology 2020 Lohse MB, Gulati M, Craik CS, Johnson AD, Nobile CJ -
A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit Candida albicans Biofilms.
Microorganisms 2020 Nobile CJ, Ennis CL, Hartooni N, Johnson AD, Lohse MB -
A population shift between two heritable cell types of the pathogen Candida albicans is based both on switching and selective proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2019 Dalal CK, Zuleta IA, Lohse MB, Zordan RE, El-Samad H, Johnson AD -
Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in mouse models of infection.
PloS one 2019 Takagi J, Singh-Babak SD, Lohse MB, Dalal CK, Johnson AD -
In Vitro Culturing and Screening of Candida albicans Biofilms.
Current protocols in microbiology 2018 Gulati M, Lohse MB, Ennis CL, Gonzalez RE, Perry AM, Bapat P, Arevalo AV, Rodriguez DL, Nobile CJ -
Development and regulation of single- and multi-species Candida albicans biofilms.
Nature reviews. Microbiology 2017 Lohse MB, Gulati M, Johnson AD, Nobile CJ -
Sensitivity of White and Opaque Candida albicans Cells to Antifungal Drugs.
Antimicrobial agents and chemotherapy 2017 Craik VB, Johnson AD, Lohse MB -
Assessment and Optimizations of Candida albicans In Vitro Biofilm Assays.
Antimicrobial agents and chemotherapy 2017 Lohse MB, Gulati M, Valle Arevalo A, Fishburn A, Johnson AD, Nobile CJ -
Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.
mBio 2016 Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ -
Global Identification of Biofilm-Specific Proteolysis in Candida albicans.
mBio 2016 Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ -
Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch.
Genetics 2016 Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD -
Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch.
mBio 2016 Hernday AD, Lohse MB, Nobile CJ, Noiman L, Laksana CN, Johnson AD -
Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching.
G3 (Bethesda, Md.) 2016 Lohse MB, Johnson AD -
Genome-Wide Chromatin Immunoprecipitation in Candida albicans and Other Yeasts.
Methods in molecular biology (Clifton, N.J.) 2016 Lohse MB, Kongsomboonvech P, Madrigal M, Hernday AD, Nobile CJ -
Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.
Proceedings of the National Academy of Sciences of the United States of America 2014 Lohse MB, Rosenberg OS, Cox JS, Stroud RM, Finer-Moore JS, Johnson AD -
How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes.
Genes & development 2014 Pérez JC, Fordyce PM, Lohse MB, Hanson-Smith V, DeRisi JL, Johnson AD -
Structure of the transcriptional network controlling white-opaque switching in Candida albicans.
Molecular microbiology 2013 Hernday AD, Lohse MB, Fordyce PM, Nobile CJ, DeRisi JL, Johnson AD -
Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains.
Proceedings of the National Academy of Sciences of the United States of America 2013 Lohse MB, Hernday AD, Fordyce PM, Noiman L, Sorrells TR, Hanson-Smith V, Nobile CJ, DeRisi JL, Johnson AD -
A conserved transcriptional regulator governs fungal morphology in widely diverged species.
Genetics 2011 Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD -
Temporal anatomy of an epigenetic switch in cell programming: the white-opaque transition of C. albicans.
Molecular microbiology 2010 Lohse MB, Johnson AD -
Distinct class of DNA-binding domains is exemplified by a master regulator of phenotypic switching in Candida albicans.
Proceedings of the National Academy of Sciences of the United States of America 2010 Lohse MB, Zordan RE, Cain CW, Johnson AD -
White-opaque switching in Candida albicans.
Current opinion in microbiology 2009 Lohse MB, Johnson AD -
Differential phagocytosis of white versus opaque Candida albicans by Drosophila and mouse phagocytes.
PloS one 2008 Lohse MB, Johnson AD