Matthew Hirschtritt, MD, MPH
Assistant Clinical Professor
Psychiatry
School of Medicine

He additionally serves as an adjunct investigator in the Kaiser Permanente Northern California Division of Research. The overarching goals of his research include improving equitable access to, quality of, and cost-effectiveness of mental health detection and treatment, focusing on under-served and marginalized communities.

Dr. Hirschtritt's investigative work has involved diverse mental health-related topics, including characteristics and treatments for obsessive-compulsive disorder, Tourette syndrome, adolescent depression and attention-deficit/hyperactivity disorder, and substance use disorders. His work has also examined the interrelationship between adolescent resiliency, peer victimization, and suicidal ideation. More recently, his work has focused on the distribution, provision, and quality of mental health care in the United States, which has involved addressing mental health stigma (specifically the harmful implications of attributing gun violence exclusively to mental illness), psychotropic prescription patterns using nationally representative data, and early identification and treatment for individuals with psychotic disorders.

In addition to his research experience, Dr. Hirschtritt has worked in various clinical psychiatric settings, including inpatient units in a safety-net, academically affiliated, and private hospitals, psychiatric emergency services, and outpatient services (including interdisciplinary clinics focused on the needs of sexual minority adults and young adults with new- or recent-onset psychosis). He is an enthusiastic educator, having designed an online curriculum for the National Neuroscience Curriculum Initiative.

Following completion of his undergraduate degree in psychology from Cornell University, Dr. Hirschtritt joined the National Institute of Mental Health as an Intramural Research Training Award recipient. He then completed his pre-medical, postbaccalaureate coursework at Johns Hopkins University, and, before beginning medical school, served as a research associate in the Yale Child Study Center. As a student in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, a five-year program dedicated to training clinician-scientists, Dr. Hirschtritt completed additional coursework in public health (leading to an MPH degree), and first came to UCSF as a Doris Duke Clinical Scholar, where he completed residency training in adult psychiatry and fellowship training in forensic psychiatry.

• Insights from California on Involuntary Commitment for Substance Use.
  The journal of the American Academy of Psychiatry and the Law 2024 Weiner SL, Bal B, Hirschtritt ME, Barnard A
• Psychiatric Diagnoses, Medication, and Service Use Among Patients Who Receive Emergency Care for Inflammatory Bowel Diseases.
  Inflammatory bowel diseases 2024 He JZ, Hirschtritt ME, Wei J, Ramalingam ND, Kahane SM, Velayos FS, Hassid BG
• Protocol for Designing a Model to Predict the Likelihood of Psychosis From Electronic Health Records Using Natural Language Processing and Machine Learning.
  The Permanente journal 2024 Stavers-Sosa I, Cronkite DJ, Gerstley LD, Kelley A, Kiel L, Kline-Simon AH, Marafino BJ, Ramaprasan A, Carrell DS, Hirschtritt ME
• Four Tips for Improving Video Telehealth Patient-Clinician Communication.
  JAMA 2024 Hirschtritt ME, Kelly S
• Changes in Service Use After Participation in an Intensive Outpatient Program Among Adults With Posttraumatic Stress Disorder.
  The Permanente journal 2024 Abeldt BM, Brown KH, Wei J, Ramalingam ND, Hirschtritt ME
• Breaking Silence, Building Resilience: Outcomes of a Course on Navigating Patient Suicide in Psychiatry Residency.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2024 Stahl HJ, Bratlie RA, Hirschtritt ME
• Reimbursement for a Broader Array of Services in Coordinated Specialty Care for Early Psychosis.
  Psychiatric services (Washington, D.C.) 2024 Hirschtritt ME, Staglin B, Buttlaire S, Ahearn K, Oglesby S, Dixon LB, Shern D, Ewing T, Niendam TA
• Experiences of transgender and gender diverse patients in emergency psychiatric settings: A scoping review.
  Journal of the American College of Emergency Physicians open 2023 O'Brien M, Hirschtritt ME, Tahir P, Kalapatapu RK
• Exploring the Complex Associations Between Prenatal and Early-Life Infections and Obsessive-Compulsive and Tic-Related Disorders.
  Biological psychiatry 2023 Hirschtritt ME, Mathews CA
• Burnout Among Psychiatry Residents and One Program's Approach to Creating a Culture of Wellness.
  The Permanente journal 2023 Brown KH, Bal B, Plauche JL, Sung D, Hirschtritt ME
• Improving Internal Medicine Residents' Comfort Managing Psychiatric Conditions Through an Interactive, Case-Based Workshop.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2023 Patel R, Ramalingam ND, Pal A, Tran HN, Hirschtritt ME
• Sleep as a vital sign.
  Sleep Science and Practice 2023 Matthew E. Hirschtritt, Matthew P. Walker, Andrew D. Krystal
• What Will It Take to Meet Adolescents' Mental Health Needs?
  The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2023 Hirschtritt ME, Rodgers CRR
• Fulfilling the Goals of 988 Through Crisis Stabilization Care.
  Psychiatric services (Washington, D.C.) 2023 Hirschtritt ME, Howard CA, Simon GE
• Electroconvulsive Therapy Anesthetic Choice and Clinical Outcomes.
  The journal of ECT 2022 Li KJ, Slama NE, Hirschtritt ME, Anshu P, Iturralde E
• Patient and Visit Characteristics Associated With Physical Restraint Use in the Emergency Department.
  The Permanente journal 2022 Walia H, Tucker LS, Manickam RN, Kene MV, Sharp AL, Berdahl CT, Hirschtritt ME
• Walking the Benzodiazepine High Wire.
  Psychiatric services (Washington, D.C.) 2022 Kroenke K, Hirschtritt ME
• Cost-Effectiveness of Motivational Interviewing to Reduce Alcohol and Cannabis Use Among Patients With Depression.
  Journal of studies on alcohol and drugs 2022 Satre DD, Parthasarathy S, Young-Wolff KC, Meacham MC, Borsari B, Hirschtritt ME, Van Dyke L, Sterling SA
• A Brief Course on Forensic Psychiatry Principles.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2022 Weiner S, Lingafelter N, Ali M, Wu J, Walia H, Wasser T, Hirschtritt ME
• A Novel Introduction to Transgender and Nonbinary Mental Health.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2022 Frawley EM, Norris R, Chen IL, Hirschtritt ME
• Association Between Prenatal Cannabis Use and Psychotropic Medication Use in Pregnant Patients With Depression and Anxiety.
  Journal of addiction medicine 2022 Hirschtritt ME, Avalos LA, Sarovar V, Ridout KK, Goler NC, Ansley DR, Satre DD, Young-Wolff KC
• Agreement between Youth Self-Report and Biospecimen-Confirmed Substance Use: A Systematic Review.
  Substance use & misuse 2022 Folk JB, Hirschtritt ME, McCrary QD, Kalapatapu RK
• Psychotropic medication prescribing during the COVID-19 pandemic.
  Medicine 2021 Hirschtritt ME, Slama N, Sterling SA, Olfson M, Iturralde E
• Risks and Benefits of Benzodiazepines-Reply.
  JAMA 2021 Hirschtritt ME, Olfson M, Kroenke K
• Cannabis Use Among Court-Involved Minority Sexual Orientation and Gender Identity Adolescents.
  The journal of the American Academy of Psychiatry and the Law 2021 Hirschtritt ME, Folk JB, Marshall BDL, Li Y, Tolou-Shams M
• Cannabis Use Among Patients With Psychotic Disorders.
  The Permanente journal 2021 Hirschtritt ME, Young-Wolff KC, Mathalon DH, Satre DD
• Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome?
  Movement disorders : official journal of the Movement Disorder Society 2021 Claudio-Campos K, Stevens D, Koo SW, Valko A, Bienvenu OJ, Budman CB, Cath DC, Darrow S, Geller D, Goes FS, Grados MA, Greenberg BD, Greenberg E, Hirschtritt ME, Illmann C, Ivankovic F, King RA, …
• Trends in Ethnicity, Race, and Sex Among Psychiatry and Non-psychiatry Residency Applicants, 2008-2019.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2021 Chen IL, Koleilat I, Choinski K, Phair J, Hirschtritt ME
• Balancing the Risks and Benefits of Benzodiazepines.
  JAMA 2021 Hirschtritt ME, Olfson M, Kroenke K
• Synaptic processes and immune-related pathways implicated in Tourette syndrome.
  Translational psychiatry 2021 Tsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, …
• Mental Health Services in a U.S. Prison During the COVID-19 Pandemic.
  Psychiatric services (Washington, D.C.) 2021 Burton PRS, Morris NP, Hirschtritt ME
• 16.1 CANNABIS USE AMONG MINORITY SEXUAL ORIENTATION AND GENDER IDENTITY, COURT-INVOLVED ADOLESCENTS.
  Journal of the American Academy of Child & Adolescent Psychiatry 2020 Matthew Hirschtritt, Johanna B. Folk, Brandon Marshall, Yu Li, Marina Tolou-Shams
• Telepsychiatry, Hospitals, and the COVID-19 Pandemic.
  Psychiatric services (Washington, D.C.) 2020 Morris NP, Hirschtritt ME
• Are Substance Use and Bullying Perpetration Two Sides of the Same Coin?
  The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2020 Hirschtritt ME
• The Kaiser Permanente Northern California Adult Alcohol Registry, an Electronic Health Records-Based Registry of Patients With Alcohol Problems: Development and Implementation.
  JMIR medical informatics 2020 Palzes VA, Weisner C, Chi FW, Kline-Simon AH, Satre DD, Hirschtritt ME, Ghadiali M, Sterling S
• Synaptic processes and immune-related pathways implicated in Tourette Syndrome.
  medRxiv 2020 Fotis Tsetsos, Dongmei Yu, Jae Hoon Sul, Alden Y Huang, Cornelia Illmann, Lisa Osiecki, Sabrina Darrow, Matthew E Hirschtritt, Erica Greenberg, Kirsten R Muller-Vahl, Manfred Stuhrmann, Yves Dion, Guy…
• Addressing Problems With Alcohol and Other Substances Among Older Adults During the COVID-19 Pandemic.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Satre DD, Hirschtritt ME, Silverberg MJ, Sterling SA
• The Kaiser Permanente Northern California Adult Alcohol Registry, an Electronic Health Records-Based Registry of Patients with Alcohol Problems: Protocol, Implementation, and Implications for Research (Preprint).
  JMIR Medical Informatics 2020 Vanessa A. Palzes, Constance Weisner, Felicia W. Chi, Andrea H. Kline-Simon, Derek D. Satre, Matthew E. Hirschtritt, Murtuza Ghadiali, Stacy Sterling
• Drug Formularies in Correctional Settings.
  The journal of the American Academy of Psychiatry and the Law 2020 Morris NP, Hirschtritt ME, Tamburello AC
• Benzodiazepine and unhealthy alcohol use among adult outpatients.
  The American journal of managed care 2019 Hirschtritt ME, Palzes VA, Kline-Simon AH, Kroenke K, Campbell CI, Sterling SA
• Variations in Application Instructions for Forensic Psychiatry Fellowships.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2019 Morris NP, Hirschtritt ME, Edwards ML
• Improving Usability of Health Information Technology.
  JAMA 2019 Hirschtritt ME, Hirschtritt DB
• Risk Assessment of Online Child Sexual Exploitation Offenders.
  The journal of the American Academy of Psychiatry and the Law 2019 Hirschtritt ME, Tucker D, Binder RL
• Symmetry and disinhibition are heritable endophenotypes for Tourette syndrome
  European Neuropsychopharmacology 2019 Mathews, C., Darrow, S., Hirschtritt, M., Yu, D., Davis, L., Scharf, J.
• Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.
  The American journal of psychiatry 2019 Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, …
• Substance Use and HIV Among Justice-Involved Youth: Intersecting Risks.
  Current HIV/AIDS reports 2019 Tolou-Shams M, Harrison A, Hirschtritt ME, Dauria E, Barr-Walker J
• Symmetry and Disinhibition are Heritable Endophenotypes For Tourette Syndrome.
  European Neuropsychopharmacology 2019 Carol Mathews, Sabrina Darrow, Matthew Hirschtritt, Dongmei Yu, Lea Davis, Jeremiah Scharf
• LGBT-Specific Education in General Psychiatry Residency Programs: a Survey of Program Directors.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2018 Hirschtritt ME, Noy G, Haller E, Forstein M
• Using Neuroscience to Make Sense of Psychopathy.
  Biological psychiatry 2018 Hirschtritt ME, Carroll JD, Ross DA
• Digital Technologies in Psychiatry: Present and Future.
  Focus (American Psychiatric Publishing) 2018 Hirschtritt ME, Insel TR
• Preparing Physician-Scientists for an Evolving Research Ecosystem.
  JAMA 2018 Hirschtritt ME, Heaton PM, Insel TR
• Analysis of shared heritability in common disorders of the brain.
  Science (New York, N.Y.) 2018 Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, …
• A Reassessment of Blaming Mass Shootings on Mental Illness.
  JAMA psychiatry 2018 Hirschtritt ME, Binder RL
• Outpatient, combined use of opioid and benzodiazepine medications in the United States, 1993-2014.
  Preventive medicine reports 2017 Hirschtritt ME, Delucchi KL, Olfson M
• Realizing E-Prescribing's Potential to Reduce Outpatient Psychiatric Medication Errors.
  Psychiatric services (Washington, D.C.) 2017 Hirschtritt ME, Chan S, Ly WO
• Development and Implementation of a Residency Area-of-Distinction in Lesbian, Gay, Bisexual, and Transgender Mental Health.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2017 Fisher WS, Hirschtritt ME, Haller E
• Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome.
  European child & adolescent psychiatry 2017 Greenberg E, Tung ES, Gauvin C, Osiecki L, Yang KG, Curley E, Essa A, Illmann C, Sandor P, Dion Y, Lyon GJ, King RA, Darrow S, Hirschtritt ME, Budman CL, Grados M, Pauls DL, Keuthen NJ, Mathews CA, …
• Screening for Depression.
  JAMA 2017 Hirschtritt ME, Kroenke K
• Deep Brain Stimulation for Obsessive-Compulsive Disorder-Reply.
  JAMA 2017 Hirschtritt ME, Bloch MH, Mathews CA
• Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.
  Neuron 2017 Huang AY, Yu D, Davis LK, Sul JH, Tsetsos F, Ramensky V, Zelaya I, Ramos EM, Osiecki L, Chen JA, McGrath LM, Illmann C, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, King RA, Dion Y,…
• Autism Spectrum Symptoms in a Tourette's Disorder Sample.
  Journal of the American Academy of Child and Adolescent Psychiatry 2017 Darrow SM, Grados M, Sandor P, Hirschtritt ME, Illmann C, Osiecki L, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA
• De Novo Coding Variants Are Strongly Associated with Tourette Disorder.
  Neuron 2017 Willsey AJ, Fernandez TV, Yu D, King RA, Dietrich A, Xing J, Sanders SJ, Mandell JD, Huang AY, Richer P, Smith L, Dong S, Samocha KE, Tourette International Collaborative Genetics (TIC Genetics), …
• 896 Genetic and Phenotypic Overlap of Specific Obsessive-Compulsive Subtypes with Tourette Syndrome.
  Biological Psychiatry 2017 Matthew Hirschtritt, Sabrina M. Darrow, Cornelia Illmann, Lisa Osiecki, Marco Grados, Paul Sandor, Yves Dion, Robert A. King, David Pauls, Cathy L. Budman, Danielle C. Cath, Erica Greenberg, Gholson J…
• Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.
  The American journal of psychiatry 2016 Darrow SM, Hirschtritt ME, Davis LK, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, …
• Child Neurology: Diagnosis and treatment of Tourette syndrome.
  Neurology 2016 Hirschtritt ME, Dy ME, Yang KG, Scharf JM
• Psychiatric Pharmacogenomics: How Close Are We?
  Biological psychiatry 2016 Hirschtritt ME, Besterman AD, Ross DA
• Handbook of Medicine in Psychiatry, 2nd ed.
  American Journal of Psychiatry Residents Journal 2016 Matthew E. Hirschtritt
• Internal resilience, peer victimization, and suicidal ideation among adolescents.
  International journal of adolescent medicine and health 2015 Hirschtritt ME, Ordóñez AE, Rico YC, LeWinn KZ
• Web-based phenotyping for Tourette Syndrome: Reliability of common co-morbid diagnoses.
  Psychiatry research 2015 Darrow SM, Illmann C, Gauvin C, Osiecki L, Egan CA, Greenberg E, Eckfield M, Hirschtritt ME, Pauls DL, Batterson JR, Berlin CM, Malaty IA, Woods DW, Scharf JM, Mathews CA
• Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.
  Journal of neurophysiology 2012 Peachey NS, Pearring JN, Bojang P, Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, Gregg RG
• Moderators of fluoxetine treatment response for children and adolescents with comorbid depression and substance use disorders.
  Journal of substance abuse treatment 2011 Hirschtritt ME, Pagano ME, Christian KM, McNamara NK, Stansbrey RJ, Lingler J, Faber JE, Demeter CA, Bedoya D, Findling RL
• Symptom-Specific Rating Scales in Child and Adolescent Psychiatry Clinical Practice.
  Child and Adolescent Psychopharmacology News 2011 Matthew E. Hirschtritt, Denise Bedoya
• Focus: The Use of Rating Scales to Track Therapeutic Progress: General Rating scales in Child and Adolescent Psychiatry Clinical Practice.
  Child and Adolescent Psychopharmacology News 2010 Matthew E. Hirschtritt, Denise Bedoya
• Focus: The Use of Rating Scales to Track Therapeutic Progress: Overview of Rating Scales in Child and Adolescent Psychiatry Clinical Practice.
  Child and Adolescent Psychopharmacology News 2010 Matthew E. Hirschtritt, Denise Bedoya
• Risks of propofol sedation/anesthesia for imaging studies in pediatric research: eight years of experience in a clinical research center.
  Archives of pediatrics & adolescent medicine 2010 Kiringoda R, Thurm AE, Hirschtritt ME, Koziol D, Wesley R, Swedo SE, O'Grady NP, Quezado ZM
• Executive and attention functioning among children in the PANDAS subgroup.
  Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence 2008 Hirschtritt ME, Hammond CJ, Luckenbaugh D, Buhle J, Thurm AE, Casey BJ, Swedo SE
• An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder.
  Journal of child and adolescent psychopharmacology 2007 Grant P, Lougee L, Hirschtritt M, Swedo SE