Matthew Alexander, MD
Assistant Clinical Professor
Radiology
School of Medicine

Publications (86)

Top publication keywords:
Intracranial AneurysmCerebrovascular DisordersEmbolization, TherapeuticCentral Nervous System Vascular MalformationsSclerosing SolutionsEndovascular ProceduresSclerotherapyCarotid-Cavernous Sinus FistulaMagnetic Resonance AngiographyIntracranial Arteriovenous MalformationsCerebral AngiographyCerebral VeinsHeadOleic AcidsIntracranial Arteriosclerosis

• Development of an MR-Guided Focused Ultrasound (MRgFUS) Lesioning Approach for the Fornix in the Rat Brain.
  Ultrasound in medicine & biology 2024 Cornelssen C, Payne A, Parker DL, Alexander M, Merrill R, Senthilkumar S, Christensen J, Wilcox KS, Odéen H, Rolston JD
• Imaging in acute ischemic stroke: Assessing findings in light of evolving therapies.
  The British journal of radiology 2024 Frias P, Khangura RS, Varjavand B, Alexander MD
• Extracranial carotid artery atherosclerotic plaque and APOE polymorphisms: a systematic review and meta-analysis.
  Frontiers in cardiovascular medicine 2023 Culleton S, Niu M, Alexander M, McNally JS, Yuan C, Parker D, Baradaran H
• Development of an MR-guided focused ultrasound (MRgFUS) lesioning approach for small and deep structures in the rat brain.
  bioRxiv : the preprint server for biology 2023 Cornelssen C, Payne A, Parker D, Alexander M, Merrill R, Senthilkumar S, Christensen J, Wilcox KS, Odéen H, Rolston JD
• Analysis of treatment cost differences in patients undergoing femoral versus radial access in outpatient diagnostic cerebral arteriograms.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2023 Findlay MC, Baker CM, Childs S, Gautam D, Salah WK, Bounajem M, Joyce E, Budohoski KP, Kilburg C, Alexander MD, Taussky P, Grandhi R

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• Hemorrhagic Safety of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Tremor without Interruption of Antiplatelet or Anticoagulant Therapy.
  Stereotactic and functional neurosurgery 2023 Caston RM, Campbell JM, Rahimpour S, Moretti P, Alexander MD, Rolston JD
• Evaluation of methemoglobin as an intravascular contrast agent: T1 relaxation time effect in a rabbit model.
  Magnetic resonance imaging 2023 Kim SE, McNally JS, Alexander MD, Zabriskie MS, Parker DL, Day RW
• Influence of cerebrospinal fluid on power absorption during transcranial magnetic resonance-guided focused ultrasound treatment.
  Medical physics 2023 Slominski E, Marchant J, Judd W, Alexander MD, Rolston JD, Odéen H, Rieke V, Christensen DA, Parker DL
• Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke.
  Journal of visualized experiments : JoVE 2023 Alexander MD, Hoareau G, Zabriskie MS, Palatinus H, Chakravarthula NR, Wang C, Johnson MA
• Association between high-risk extracranial carotid plaque and covert brain infarctions and cerebral microbleeds.
  Neuroradiology 2022 Baradaran H, Culleton S, Stoddard G, Alexander MD, Romero JR, Hadley JR, Kim SE, Parker DL, McNally JS
• Direct cost analysis of rapid MRI in the emergency department evaluation of patients suspected of having acute ischemic stroke*.
  The neuroradiology journal 2022 de Havenon A, Orlando C, Delic A, McNally JS, Majersik JJ, Harman T, Alexander M, Reddy V, Lyden S, Anzai Y
• Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders.
  Translational research : the journal of laboratory and clinical medicine 2022 Malona J, Chuaqui C, Seletsky BM, Beebe L, Cantin S, Kalken DV, Fahnoe K, Wang Z, Browning B, Szabo H, Koopman LA, Oravecz T, McDonald JJ, Ramirez-Valle F, Gaur R, Mensah KA, Thomas M, Connarn JN, Hu …
• Idiopathic intracranial hypertension imaging approaches and the implications in patient management.
  The British journal of radiology 2022 Sarrami AH, Bass DI, Rutman AM, Alexander MD, Aksakal M, Zhu C, Levitt MR, Mossa-Basha M
• Neutrophil extracellular traps regulate ischemic stroke brain injury.
  The Journal of clinical investigation 2022 Denorme F, Portier I, Rustad JL, Cody MJ, de Araujo CV, Hoki C, Alexander MD, Grandhi R, Dyer MR, Neal MD, Majersik JJ, Yost CC, Campbell RA
• Spatially resolved transcriptomics for evaluation of intracranial vessels in a rabbit model: Proof of concept.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2022 Zabriskie MS, Cooke DL, Wang C, Alexander MD
• Balance and cognitive impairments are prevalent and correlated with age in presurgical patients with essential tremor.
  Clinical parkinsonism & related disorders 2022 Campbell JM, Ballard J, Duff K, Zorn M, Moretti P, Alexander MD, Rolston JD
• Delayed-Onset Cranial Nerve Palsy After Transvenous Embolization of Indirect Carotid Cavernous Fistulas.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2021 Wang A, Halbach VV, Dowd CF, Alexander MD, Hallam DK, Ghodke B, Moazami G, Mandigo GK, Lavine SD, Meyers PM
• MR Angiography Series: Neurovascular MR Angiography.
  Radiographics : a review publication of the Radiological Society of North America, Inc 2021 Costello J, Alexander MD, McNally JS, Hecht EM, Porambo ME, Lau VC, DeMarco JK
• Carotid Compliance and Parahippocampal and Hippocampal Volume over a 20-Year Period.
  Dementia and geriatric cognitive disorders extra 2021 Baradaran H, Delic A, McNally JS, Alexander M, Majersik JJ, Parker DL, de Havenon A
• MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy.
  Topics in magnetic resonance imaging : TMRI 2021 Muddasani V, de Havenon A, McNally JS, Baradaran H, Alexander MD
• Differentiation of symptomatic and asymptomatic carotid intraplaque hemorrhage using 3D high-resolution diffusion-weighted stack of stars imaging.
  NMR in biomedicine 2021 Kim SE, Parker DL, Roberts JA, Treiman GS, Alexander M, Baradaran H, de Havenon A, McNally JS
• Postmarket American Experience With Woven EndoBridge Device: Adjudicated Multicenter Case Series.
  Neurosurgery 2021 Cherian J, Chen SR, Puri A, Vakharia K, Levy E, Eshraghi S, Howard BM, Tong FC, Cawley CM, Gross B, Alexander MD, Grandhi R, Srinivasan VM, Burkhardt JK, Johnson JN, Kan P
• Predicting neuroimaging eligibility for extended-window endovascular thrombectomy.
  Journal of neurosurgery 2021 de Havenon A, Mickolio K, O'Donnell S, Stoddard G, McNally JS, Alexander M, Taussky P, Awad AW
• Using Ultrasound and Inflammation to Improve Prediction of Ischemic Stroke: A Secondary Analysis of the Multi-Ethnic Study of Atherosclerosis.
  Cerebrovascular diseases extra 2021 Baradaran H, Delic A, Wong KH, Sheibani N, Alexander M, McNally JS, Majersik JJ, De Havenon A
• Duration of symptomatic stroke and successful reperfusion with endovascular thrombectomy for anterior circulation large vessel occlusive stroke.
  Journal of neurointerventional surgery 2021 de Havenon A, Alexander MD, Nogueira RG, Haussen DC, Castonguay AC, Linfante I, Johnson MA, Nguyen TN, Mokin M, Zaidat OO
• Blood Pressure Management Before, During, and After Endovascular Thrombectomy for Acute Ischemic Stroke.
  Seminars in neurology 2021 de Havenon A, Petersen N, Sultan-Qurraie A, Alexander M, Yaghi S, Park M, Grandhi R, Mistry E
• "And do no harm": Complications in interventional neuroradiology.
  Handbook of clinical neurology 2021 Alexander MD, Halbach VV, Hetts SW
• Cerebral arteriovenous fistulae.
  Handbook of clinical neurology 2021 Alexander MD, Darflinger R, Cooke DL, Halbach VV
• Neurovascular arterial anatomy: Brain, head, and neck.
  Handbook of clinical neurology 2021 Alexander MD, Hutcheson D, Lawton M
• Neurovascular venous anatomy: Brain, head, and neck.
  Handbook of clinical neurology 2021 Alexander MD, Hutcheson D, Lawton M
• Rabbit models of intracranial atherosclerotic disease for pathological validation of vessel wall MRI.
  The neuroradiology journal 2020 McNally JS, Havenon A, Kim SE, Wang C, Wang S, Zabriskie MS, Parker DL, Baradaran H, Alexander MD
• Endovascular Thrombectomy for Pediatric Acute Ischemic Stroke: A Multi-Institutional Experience of Technical and Clinical Outcomes.
  Neurosurgery 2020 Ravindra VM, Alexander M, Taussky P, Bollo RJ, Hassan AE, Scoville JP, Griauzde J, Awad AW, Jumaa M, Zaidi S, Lee JJ, Hafeez MU, Nascimento FA, LoPresti MA, Couldwell WT, Hetts SW, Lam SK, Kan P, …
• Carotid artery plaque characteristics: current reporting practices on CT angiography.
  Neuroradiology 2020 Baradaran H, Foster T, Harrie P, McNally JS, Alexander M, Pandya A, Anzai Y, Gupta A
• Prediction of death after endovascular thrombectomy in the extended window: a secondary analysis of DEFUSE 3 ".
  Journal of neurointerventional surgery 2020 Taussky P, Agnoletto G, Grandhi R, Alexander MD, Wong KH, Albers GW, de Havenon A
• Hypoperfusion Distal to Anterior Circulation Intracranial Atherosclerosis is Associated with Recurrent Stroke.
  Journal of neuroimaging : official journal of the American Society of Neuroimaging 2020 de Havenon A, Khatri P, Prabhakaran S, Yeatts SD, Peterson C, Sacchetti D, Alexander M, Cutting S, Grory BM, Furie K, Liebeskind DS, Yaghi S
• Apolipoprotein E knockout rabbit model of intracranial atherosclerotic disease.
  Animal models and experimental medicine 2020 Zabriskie MS, Wang C, Wang S, Alexander MD
• End-of-Treatment Intracerebral and Ventricular Hemorrhage Volume Predicts Outcome: A Secondary Analysis of MISTIE III.
  Stroke 2019 de Havenon A, Joyce E, Yaghi S, Ansari S, Delic A, Taussky P, Alexander M, Tirschwell D, Grandhi R
• Methemoglobin Modulation as an Intravascular Contrast Agent for Magnetic Resonance Imaging: Proof of Concept.
  Frontiers in veterinary science 2019 McNally JS, Jaffey JA, Kim SE, Alexander MD, Shumway KL, Cohn LA, Parker DL, Day RW
• Subclinical Cerebrovascular Disease: Epidemiology and Treatment.
  Current atherosclerosis reports 2019 de Havenon A, Meyer C, McNally JS, Alexander M, Chung L
• Long-Term Outcomes of Endovascular Treatment of Indirect Carotid Cavernous Fistulae: Superior Efficacy, Safety, and Durability of Transvenous Coiling Over Other Techniques.
  Neurosurgery 2019 Alexander MD, Halbach VV, Hallam DK, Cooke DL, Ghodke BV, Dowd CF, Amans MR, Hetts SW, Higashida RT, Meyers PM
• Results From DEFUSE 3: Good Collaterals Are Associated With Reduced Ischemic Core Growth but Not Neurologic Outcome
  Stroke 2019 de Havenon A, Mlynash M, Kim-Tenser MA, Lansberg MG, Leslie-Mazwi T, Christensen S, McTaggart RA, Alexander M, Albers G, Broderick J, Marks MP, Heit JJ, DEFUSE 3 Investigators
• Relationship of clinical presentation and angiographic findings in patients with indirect cavernous carotid fistulae.
  Journal of neurointerventional surgery 2019 Alexander MD, Halbach VV, Hallam DK, Cooke DL, Ghodke B, Dowd CF, Amans MR, Hetts SW, Higashida RT, Meyers PM
• Assessment of quantitative methods for enhancement measurement on vessel wall magnetic resonance imaging evaluation of intracranial atherosclerosis.
  Neuroradiology 2019 Alexander MD, de Havenon A, Kim SE, Parker DL, McNally JS
• Assessment of cell yield among different devices for endovascular biopsy to harvest vascular endothelial cells.
  BioTechniques 2019 Alexander MD, Sun Z, Conrad MB, Cooke DL
• Bilateral blunt cerebrovascular injury resulting in direct carotid-cavernous fistulae: A case report and review of the literature.
  Surgical neurology international 2018 Avila SV, Noy BV, Karsy M, Alexander M, Rolston JD
• Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm.
  Journal of neurointerventional surgery 2018 Morrison J, Alexander MD, Dowd CF, Cooke DL
• Targeted Embolization of Aneurysms Associated With Brain Arteriovenous Malformations at High Risk for Surgical Resection: A Case-Control Study.
  Neurosurgery 2018 Alexander MD, Hippe DS, Cooke DL, Hallam DK, Hetts SW, Kim H, Lawton MT, Sekhar LN, Kim LJ, Ghodke BV
• Improved procedural safety following protocol changes for selective ophthalmic arterial infusion of chemotherapy for treatment of ocular retinoblastoma.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2018 Ammanuel S, Alexander MD, Damato B, Cooke DL, Halbach VV, Amans MR, Dowd CF, Higashida RT, Hetts SW
• Estimation of intra-arterial chemotherapy distribution to the retina in pediatric retinoblastoma patients using quantitative digital subtraction angiography.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2018 Kondapavulur S, Cooke DL, Kao A, Amans MR, Alexander M, Darflinger R, Dowd CF, Higashida RT, Damato B, Halbach VV, Matthay KK, Hetts SW
• Predictors of intracranial hemorrhage volume and distribution in brain arteriovenous malformation.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2018 Yu JF, Nicholson AD, Nelson J, Alexander MD, Tse SH, Hetts SW, Hemphill JC, Kim H, Cooke DL
• Technical factors affecting outcomes following endovascular treatment of posterior circulation atherosclerotic lesions.
  Surgical neurology international 2017 Alexander MD, Rebhun JM, Hetts SW, Amans MR, Settecase F, Darflinger RJ, Dowd CF, Halbach VV, Higashida RT, Cooke DL
• Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2017 Settecase F, McCoy DB, Darflinger R, Alexander MD, Cooke DL, Dowd CF, Hetts SW, Higashida RT, Halbach VV, Amans MR
• Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm.
  BMJ case reports 2017 Morrison J, Alexander MD, Dowd CF, Cooke DL
• Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility.
  Biomedical microdevices 2017 Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW
• Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging.
  PloS one 2016 Lum MA, Martin AJ, Alexander MD, McCoy DB, Cooke DL, Lillaney P, Moftakhar P, Amans MR, Settecase F, Nicholson A, Dowd CF, Halbach VV, Higashida RT, McDermott MW, Saloner D, Hetts SW
• Revisiting Current Golden Rules in Managing Acute Ischemic Stroke: Evaluation of New Strategies to Further Improve Treatment Selection and Outcome.
  AJR. American journal of roentgenology 2016 Yuh WT, Alexander MD, Ueda T, Maeda M, Taoka T, Yamada K, Beauchamp NJ
• Transvenous ethanol sclerotherapy of feeding arteries for treatment of a dural arteriovenous fistula.
  Journal of neurointerventional surgery 2016 Alexander MD, Halbach V, Nicholson A, Settecase F, Darflinger RJ, Amans MR
• Transvenous ethanol sclerotherapy of feeding arteries for treatment of a dural arteriovenous fistula.
  BMJ case reports 2016 Alexander MD, Halbach V, Nicholson A, Settecase F, Darflinger RJ, Amans MR
• Added Value of Vessel Wall Magnetic Resonance Imaging in the Differentiation of Moyamoya Vasculopathies in a Non-Asian Cohort.
  Stroke 2016 Mossa-Basha M, de Havenon A, Becker KJ, Hallam DK, Levitt MR, Cohen WA, Hippe DS, Alexander MD, Tirschwell DL, Hatsukami T, Amlie-Lefond C, Yuan C
• Less can be more: Targeted embolization of aneurysms associated with arteriovenous malformations unsuitable for surgical resection.
  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2016 Alexander MD, Cooke DL, Hallam DK, Kim H, Hetts SW, Ghodke BV
• Vessel wall imaging for intracranial vascular disease evaluation.
  Journal of neurointerventional surgery 2016 Mossa-Basha M, Alexander M, Gaddikeri S, Yuan C, Gandhi D
• Electrophilic Oxidation and [1,2]-Rearrangement of the Biindole Core of Birinapant.
  ACS medicinal chemistry letters 2016 Deng Y, Haimowitz T, LaPorte MG, Rippin SR, Alexander MD, Kumar PT, Hendi MS, Lee YH, Condon SM
• High-resolution intracranial vessel wall imaging: imaging beyond the lumen.
  Journal of neurology, neurosurgery, and psychiatry 2016 Alexander MD, Yuan C, Rutman A, Tirschwell DL, Palagallo G, Gandhi D, Sekhar LN, Mossa-Basha M
• Lesion location, stability, and pretreatment management: factors affecting outcomes of endovascular treatment for vertebrobasilar atherosclerosis.
  Journal of neurointerventional surgery 2015 Alexander MD, Rebhun JM, Hetts SW, Kim AS, Nelson J, Kim H, Amans MR, Settecase F, Dowd CF, Halbach VV, Higashida RT, Cooke DL
• Intraarterial treatment for acute ischemic stroke.
  The New England journal of medicine 2015 Yuh WT, Alexander MD, Beauchamp NJ
• Quantitative volumetric analysis of head and neck venous and lymphatic malformations to assess response to percutaneous sclerotherapy.
  Acta radiologica (Stockholm, Sweden : 1987) 2015 Alexander MD, McTaggart RA, Choudhri OA, Pandit RP, Wu A, Ross M, Do HM
• Utility of clinical and radiographic findings in the management of traumatic epidural hematoma.
  Pediatric neurosurgery 2014 Flaherty BF, Loya J, Alexander MD, Pandit R, Ha BY, Torres RA, Schroeder AR
• Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.
  Journal of medicinal chemistry 2014 Condon SM, Mitsuuchi Y, Deng Y, LaPorte MG, Rippin SR, Haimowitz T, Alexander MD, Kumar PT, Hendi MS, Lee YH, Benetatos CA, Yu G, Kapoor GS, Neiman E, Seipel ME, Burns JM, Graham MA, McKinlay MA, Li X…
• Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
  Molecular cancer therapeutics 2014 Benetatos CA, Mitsuuchi Y, Burns JM, Neiman EM, Condon SM, Yu G, Seipel ME, Kapoor GS, Laporte MG, Rippin SR, Deng Y, Hendi MS, Tirunahari PK, Lee YH, Haimowitz T, Alexander MD, Graham MA, Weng D, Shi…
• Percutaneous sclerotherapy with ethanolamine oleate for venous malformations of the head and neck.
  Journal of neurointerventional surgery 2013 Alexander MD, McTaggart RA, Choudhri OA, Marcellus ML, Do HM
• Percutaneous sclerotherapy with ethanolamine oleate for lymphatic malformations of the head and neck.
  Journal of neurointerventional surgery 2013 Alexander MD, McTaggart RA, Choudhri OA, Marcellus ML, Do HM
• Multimodality evaluation of dural arteriovenous fistula with CT angiography, MR with arterial spin labeling, and digital subtraction angiography: case report.
  Journal of neuroimaging : official journal of the American Society of Neuroimaging 2013 Alexander M, McTaggart R, Santarelli J, Fischbein N, Marks M, Zaharchuk G, Do H
• Occipital artery anastomosis to vertebral artery causing pulsatile tinnitus.
  Journal of neurointerventional surgery 2013 Alexander MD, English J, Hetts SW
• Occipital artery anastomosis to vertebral artery causing pulsatile tinnitus.
  BMJ case reports 2013 Alexander MD, English J, Hetts SW
• Power-injectable ports: safety during placement, therapeutic use, and contrast administration during computed tomography procedures.
  The journal of vascular access 2012 Alexander MD, Morrison HL
• Two- and three-dimensional culture of keratinocyte stem and precursor cells derived from primary murine epidermal cultures.
  Stem cell reviews and reports 2012 Vollmers A, Wallace L, Fullard N, Höher T, Alexander MD, Reichelt J
• Supernova hemorrhage: obliterative hemorrhage of brain arteriovenous malformations following γ knife radiosurgery.
  Journal of neurointerventional surgery 2011 Alexander MD, Hetts SW, Young WL, Halbach VV, Dowd CF, Higashida RT, English JD
• Prospective audit of patients with haemophilia: bleeding episodes and management.
  Journal of paediatrics and child health 2011 Alexander M, Barnes C, Barnett P
• Field study of hydrogeologic characterization methods in a heterogeneous aquifer.
  Ground water 2011 Alexander M, Berg SJ, Illman WA
• Synthetic studies on the mycolactone core.
  Organic & biomolecular chemistry 2010 Ko KS, Alexander MD, Fontaine SD, Biggs-Houck JE, La Clair JJ, Burkart MD
• Revisiting normal perfusion pressure breakthrough in light of hemorrhage-induced vasospasm.
  World journal of radiology 2010 Alexander MD, Connolly ES, Meyers PM
• Synthesis of isopeptide epoxide peptidomimetics.
  The Journal of organic chemistry 2009 Majumdar D, Alexander MD, Coward JK
• Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis.
  ACS chemical biology 2006 Worthington AS, Rivera H, Torpey JW, Alexander MD, Burkart MD
• Synthesis of the mycolactone core by ring-closing metathesis.
  Chemical communications (Cambridge, England) 2006 Alexander MD, Fontaine SD, La Clair JJ, Dipasquale AG, Rheingold AL, Burkart MD
• A central strategy for converting natural products into fluorescent probes.
  Chembiochem : a European journal of chemical biology 2006 Alexander MD, Burkart MD, Leonard MS, Portonovo P, Liang B, Ding X, Joullié MM, Gulledge BM, Aggen JB, Chamberlin AR, Sandler J, Fenical W, Cui J, Gharpure SJ, Polosukhin A, Zhang HR, Evans PA, …
• Variability and comparison of hyporheic water temperatures and seepage fluxes in a small Atlantic salmon stream.
  Ground water 2003 Alexander MD, Caissie D