Masis Isikbay, MD
Assistant Professor
Radiology
School of Medicine

Dr. Isikbay has taught trainees of all levels by participating in courses offered by the UCSF School of Medicine, mentoring pre-medical and medical students, leading symposia with hands-on radiology training, and has lectured on the regional, national, and international level on a variety of education topics. He created the medical education website, www.stepwards.com, (with an accompanying YouTube.com channel) which hosts a broad range of content including diagnostic imaging search patterns, procedural videos and an online call preparation curriculum for radiology trainees worldwide for which he received an international RSNA education grant. Dr. Isikbay has also contributed to a variety of quality improvement projects such as body and neuro IR post procedure order sets, first-year resident rotation guides, and primers for new trainees in diagnostic and interventional radiology. His dedication to clinical work and education earned Dr. Isikbay the 2023 Elmer Ng Outstanding Resident in Diagnostic Radiology award.

Dr. Isikbay is a former NIH T-32 research scholar (2022-2023) whose work focuses on improving clinical care and spans a variety of topics including: the COVID-19 diagnostic pathway, machine learning mediated imaging post-processing, and diagnostic/procedural medical education. Dr. Isikbay worked with the UCSF neuroendovascular department to create an updated classification system for shunting arteriovenous lesions of the spine. He was nominated as one of 2023's most influential radiology researchers by AutMinnie.com.

Additionally, Dr. Isikbay is a deputy editor for the journal Radiology and was awarded the RSNA’s Olmstead Editorial Fellowship (2023-2024). Dr. Isikbay remains active in many different radiological societies serving on the neuroradiology practice parameters committee for the ACR and on the education committee for the ASNR.

• A Deep Learning Approach for Automated Bone Removal from Computed Tomography Angiography of the Brain.
  Journal of digital imaging 2023 Isikbay M, Caton MT, Calabrese E
• Transitional vascular anomaly of a persistent medial procephalic vein causing obstructive hydrocephalus and intracranial haemorrhage.
  BJR case reports 2022 Isikbay M, Narsinh K, Caton M, Amans M
• Tradeoffs associated with autotomy and regeneration and their potential role in the evolution of regenerative abilities.
  Behavioral Ecology 2022 Tara Prestholdt, Tai White-Toney, Katie Bates, Kara Termulo, Sawyer Reid, Katy Kennedy, Zach Turley, Clayton Steed, Ryan Kain, Matt Ortman, Tim Luethke, Spencer Degerstedt, Masis Isikbay
• Transvenous Approaches to the Vertebral-Venous Plexus for Endovascular Treatment of Cervical Epidural Arteriovenous Fistulas: Anatomy and Technique.
  Stroke Vascular and Interventional Neurology 2022 Michael T. Caton, Masis Isikbay, Kazim H. Narsinh, Amanda Baker, James Milburn, Daniel L. Cooke, Steven W. Hetts, Christopher F. Dowd, Randall T. Higashida, Matthew R. Amans
• Visceral Aneurysm Formation and Intraabdominal Hemorrhage Associated with Immune Checkpoint Inhibitor Therapy.
  Journal of vascular and interventional radiology : JVIR 2020 Lee AY, Lam A, Hicks RM, Isikbay M, Heller MB, Sugi MD, Behr S, Kohi MP
• A different type of machine learning: optimizing ultrasound ergonomics during image guided procedures.
  2020 Masis Isikbay
• Traumatic testicular rupture: Multimodality imaging with intraoperative correlate.
  Clinical imaging 2020 Isikbay M, Sugi MD, Bowman MS, Choi HH
• Computed tomography perfusion abnormalities after carotid endarterectomy help in the diagnosis of reversible cerebral vasoconstriction syndrome.
  Journal of vascular surgery cases and innovative techniques 2020 Isikbay M, Narsinh KH, Arroyo S, Smith WS, Cooke DL, Higashida RT, Amans MR
• When to rule out COVID-19: How many negative RT-PCR tests are needed?
  Respiratory medicine case reports 2020 Isikbay M, Henry TS, Frank JA, Hope MD
• CT on the Diamond Princess: What Might This Tell Us About Sensitivity for COVID-19?
  Radiology. Cardiothoracic imaging 2020 Isikbay M, Hope MD, Raptis CA, Shah A, Bierhals AJ, Bhalla S, Hammer MM, Kligerman SJ, Jeudy J, Filev PD, Henry TS
• Family history of prostate cancer and the incidence of ERG- and phosphatase and tensin homolog-defined prostate cancer.
  International journal of cancer 2019 Hashim D, Gonzalez-Feliciano AG, Ahearn TU, Pettersson A, Barber L, Pernar CH, Ebot EM, Isikbay M, Finn SP, Giovannucci EL, Lis RT, Loda M, Parmigiani G, Lotan T, Kantoff PW, Mucci LA, Graff RE
• Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.
  Xenobiotica; the fate of foreign compounds in biological systems 2017 House L, Seminerio MJ, Mirkov S, Ramirez J, Skor M, Sachleben JR, Isikbay M, Singhal H, Greene GL, Vander Griend D, Conzen SD, Ratain MJ
• Abstract 4236: Gene expression profiling of prostate tissue identifies biological pathways associated with TMPRSS2:ERG gene fusion.
  Epidemiology 2017 Ericka Ebot, Masis Isikbay, Travis Gerke, Thomas U. Ahearn, Rachel S. Kelly, Svitlana Tyekucheva, Andreas Pettersson, Kathryn L. Penney, Lorelei A. Mucci
• Perineural Invasion and Risk of Lethal Prostate Cancer.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Zareba P, Flavin R, Isikbay M, Rider JR, Gerke TA, Finn S, Pettersson A, Giunchi F, Unger RH, Tinianow AM, Andersson SO, Andrén O, Fall K, Fiorentino M, Mucci LA, Transdisciplinary Prostate Cancer …
• Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer.
  Oncotarget 2016 Kregel S, Chen JL, Tom W, Krishnan V, Kach J, Brechka H, Fessenden TB, Isikbay M, Paner GP, Szmulewitz RZ, Vander Griend DJ
• Genetic variants in cell cycle control pathway confer susceptibility to aggressive prostate carcinoma.
  The Prostate 2015 Kibel AS, Ahn J, Isikbay M, Klim A, Wu WS, Hayes RB, Isaacs WB, Daw EW
• Molecular analysis of CD133-positive circulating tumor cells from patients with metastatic castration-resistant prostate cancer.
  Journal of translational science 2015 Reyes EE, Gillard M, Duggan R, Wroblewski K, Kregel S, Isikbay M, Kach J, Brechka H, Weele DJ, Szmulewitz RZ, Griend DJ
• The effects of cheliped autotomy and regeneration on aggression in purple shore crabs (Hemigrapsus nudus).
  Marine and Freshwater Behaviour and Physiology 2015 Tara L. Maginnis, Masis Isikbay, Spencer G. Degerstedt, Timothy J. Luethke, Matthew Ortman
• Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer.
  Journal of translational medicine 2014 Reyes EE, VanderWeele DJ, Isikbay M, Duggan R, Campanile A, Stadler WM, Vander Griend DJ, Szmulewitz RZ
• Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer.
  Hormones & cancer 2014 Isikbay M, Otto K, Kregel S, Kach J, Cai Y, Vander Griend DJ, Conzen SD, Szmulewitz RZ
• Androgen receptor independent acquired mechanisms of resistance to enzalutamide in castration-resistant prostate cancer.
  Journal of Clinical Oncology 2014 Russell Zelig Szmulewitz, Steve Kregel, Masis Isikbay, Yi Cai, James Lin Chen, Donald J Vander Griend
• Feasibility of multimodal molecular characterization of the androgen receptor (AR) in circulating tumor cells (CTCs) from patients with castrate-resistant prostate cancer (CRPC).
  Journal of Clinical Oncology 2014 David James VanderWeele, Masis Isikbay, Edwin Reyes, Ryan Duggan, Alicia J. Wyche, Walter Michael Stadler, Donald Vander Griend, Russell Zelig Szmulewitz
• A size comparison of beta-galactosidase isolated from fibroblasts from normal and GM1-affected sheep.
  Molecular Genetics and Metabolism 2013 Amelia Ahern-Rindell, Masis Isikbay
• Evaluation of GLB1 In a Novel Ovine Model of GM1-Gangliosidosis.
  Molecular Genetics and Metabolism 2012 Amelia Ahern-Rindell, Masis Isikbay, Bethany McInturff, Megan Supinski