Mary Jue Xu, MD
Assistant Professor
Otolaryngology
School of Medicine
Mary Jue Xu, MD, is a head and neck oncology, endocrine, transoral robotic, and microvascular surgeon working at the University of California San Francisco (UCSF) and the Zuckerberg San Francisco General Hospital. She works toward bettering the lives of cancer patients through direct patient care and through studying interventions to improve access to quality cancer care in resource-constrained health systems.
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She studied biology at the Massachusetts Institute of Technology and completed her medical degree in the Harvard-MIT Health Sciences and Technology program. During medical school, she spent a year at Butaro Cancer Center in Rwanda studying clinical outcomes of pediatric malignancies. During her otolaryngology-head and neck surgery residency at UCSF, she worked with Dr. Aslam Nkya, a head and neck surgeon in Tanzania, on projects assessing rates of human papillomavirus-associated head and neck cancers in Tanzania. She co-founded the Global Otolaryngology-Head and Neck Surgery Initiative, an international research collaboration, and has worked on projects including a global otolaryngology-head and neck surgery workforce assessment. Her ongoing research is focused on improving access to head and neck cancer care both domestically and internationally.
Education & Training
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- MD Medical degree Harvard Medical School
- BS Biology Massachusetts Institute of Technology
- Otolaryngology-Head and Neck Surgery Residency University of California San Francisco
- Head and Neck Oncology, Robotic Surgery, Microvascular Reconstruction Fellowship University of Pennsylvania
Interests
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- Transoral Robotic Surgery
- Global Health
- Cancer
- Global Surgery
- Global Otolaryngology-Head and Neck Surgery
- Otolaryngology-Head and Neck Surgery
- Microvascular Reconstructive Surgery
Publications (46)
Top publication keywords:
Hearing LossPapillomavirus InfectionsTime-to-TreatmentHemorrhagic Fever, EbolaPandemicsSurgical Procedures, OperativeHead and Neck NeoplasmsOtolaryngologyOropharyngeal NeoplasmsSalivary Gland DiseasesSalivary Gland NeoplasmsAutoimmune DiseasesSalivary Gland CalculiFree Tissue FlapsCarcinoma, Squamous Cell
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Treatment initiation and completion among head and neck squamous cell carcinoma patients in Tanzania.
BMC research notes 2024 Xu MJ, Haddadi S, Mushi BP, Zhang L, Sama G, Nyagabona SK, Ng D, Muya S, Malango AE, Richard E, Ha P, Yom SS, Massawe W, Mmbaga EJ, Van Loon K, Nkya A -
Using context-specific evidence to inform resource-stratified cancer guidelines: A call for a new approach.
Cancer 2024 Buckle GC, DeBoer R, Xu MJ, Mrema A, Rubagumya F, Velloza J, Falade AS, Van Loon K -
Characterizing Baseline Prevalence and Causes of Complications of Tracheostomy and Gastrostomy Tubes Among Cancer Patients at Muhimbili National Hospital in Tanzania.
JCO Global Oncology 2024 Leyda Marrero Morales, Ivy Maina, Aslam Nkya, Beatrice P. Mushi, Mary Jue Xu, Nazima Dharsee, Nashivai Elias, Katherine Van Loon, Elia Mmbaga, Msiba Selekwa -
Addressing inequities in the otolaryngology academic publishing: A call to action.
Journal of the Colleges of Medicine of South Africa 2024 Sarah Nuss, Rolvix H. Patterson, Mary J. Xu, Amina Seguya, Valerie Salano, Nader Zalaquett, Samuel Okerosi, Bethany Hedt-Gauthier, Johannes Fagan -
Paediatric airway foreign-body removal equipment availability in sub-Saharan Africa.
Journal of the Colleges of Medicine of South Africa 2024 Fiona Kabagenyi, Alexander D. Cherches, Nina R. Patel, Samuel N. Okerosi, Mary Jue Xu, Wale L. Gellaw, Tagwa H.A. Abdalla, Felicia Tshite, Buhlebenkosi J. Hlomani, Titus Dzongodza, Reuel K. Maina, …
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Prognostic risk factors of buccal squamous cell carcinoma: A case-control study.
Head & neck 2024 Callander JK, Souza SS, Eltawil Y, El-Sayed IH, George JR, Ha P, Ryan WR, Xu MJ, Heaton CM -
Tracheostomy care quality improvement in low- and middle-income countries: A scoping review.
PLOS global public health 2023 Selekwa M, Maina I, Yeh T, Nkya A, Ncogoza I, Nuss RC, Mushi BP, Haddadi S, Van Loon K, Mbaga E, Massawe W, Roberson DW, Dharsee N, Musimu B, Xu MJ -
The Global Otolaryngology-Head and Neck Surgery Workforce.
JAMA otolaryngology-- head & neck surgery 2023 Petrucci B, Okerosi S, Patterson RH, Hobday SB, Salano V, Waterworth CJ, Brody RM, Sprow H, Alkire BC, Fagan JJ, Tamir SO, Der C, Bhutta MF, Maina IW, Pang JC, Daudu D, Mukuzi AG, Srinivasan T, … -
Treatment Modality Impact on Patient-Reported Quality of Life in Human Papilloma Virus-Associated Oropharyngeal Carcinoma.
The Laryngoscope 2023 Plonowska-Hirschfeld KA, Gulati A, Stephens EM, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi A, Kang H, Ryan WR -
Realities and challenges of head and neck free flap reconstruction in sub-Saharan Africa.
Current opinion in otolaryngology & head and neck surgery 2023 Okerosi S, Nkya A, Fagan J, Xu MJ -
Human Papillomavirus-Associated Oropharyngeal Cancer: Global Epidemiology and Public Policy Implications.
Cancers 2023 Ndon S, Singh A, Ha PK, Aswani J, Chan JY, Xu MJ -
An analysis of the inclusion of ear and hearing care in national health policies, strategies and plans.
Health policy and planning 2023 Canick J, Petrucci B, Patterson R, Saunders J, Htoo Thaw M, Omosule I, Denton A, Xu MJ, Chadha S, Young G, Siafa L, Mortel O, Shamshad A, Reddy A, McCalla M, Prasad K, Yang HH, Pan DR, Shah J, Smith E… -
A prospective evaluation of neck and shoulder function following treatments of early-stage human papillomavirus-associated oropharynx cancer.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Gulati A, Plonowska-Hirschfeld K, Stephens EM, Kansara S, Zebolsky AL, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi AP, Kang H, Ryan WR -
Essential equipment and services for otolaryngology care: a proposal by the Global Otolaryngology-Head and Neck Surgery Initiative.
Current opinion in otolaryngology & head and neck surgery 2023 Srinivasan T, Cherches A, Seguya A, Salano V, Patterson RH, Xu MJ, Alkire BC, Okerosi SN, Tamir SO -
Response to Letter to the Editor Regarding "Delphi Method Consensus on Priority Global Otolaryngology-Head and Neck Surgery Conditions and Procedures".
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2023 Nuss S, Patterson RH, Wiedermann J, Cahill GL, Alkire B, Okerosi S, Xu MJ -
Human Papillomavirus-Associated Head and Neck Malignancies in Sub-Saharan Africa: A Systematic Review.
JCO global oncology 2023 Okerosi S, Mokoh LW, Rubagumya F, Niyibizi BA, Nkya A, Van Loon K, Buckle G, Bent S, Ha P, Fagan JJ, Ng D, Aswani J, Xu MJ -
Characterizing critical predictors of an academic career following head and neck fellowship in otolaryngology.
Head & neck 2022 Suresh NV, Xu MJ, Harris J, Balar E, Barrette LX, Chorath KT, Moreira AG, Rajasekaran K -
Microsurgical resection of an intravestibular schwannoma: a review of surgical technique and management considerations.
Neurosurgical focus: Video 2021 Morshed RA, Haddad AF, Raygor KP, Xu MJ, Limb CJ, Theodosopoulos PV -
Letter to the Editor Response Regarding "Research Equity in Otolaryngology-Head and Neck Surgery".
OTO open 2021 Patterson RH, Xu MJ, Okerosi S, Bhutta MF, Der C, Alkire B, Njogu R, Vendra V, Tamir SO, Fagan JJ -
Research Equity in Otolaryngology-Head and Neck Surgery.
OTO open 2021 Patterson RH, Xu MJ, Okerosi S, Bhutta MF, Der C, Alkire B, Njogu R, Vendra V, Tamir SO, Fagan JJ -
Practical Salivary Ultrasound Imaging Tips and Pearls.
Otolaryngologic clinics of North America 2021 Xu MJ, Chang JL -
Oncologic outcomes of human papillomavirus-associated oropharynx carcinoma treated with surgery alone: A 12-institution study of 344 patients.
Cancer 2021 Ryan WR, Xu MJ, Ochoa E, Plonowska-Hirschfeld KA, Zebolsky AL, Ha PK, Bewley AF, Mallen-St Clair J, Joshi AS, Coffey CS, Faraji F, MacDonald BV, Houlton JJ, Gobillot TA, Curry JM, Philips R, Hackman … -
Communication Chaos from Discrepancies in Personal Protective Equipment and Preoperative Guidelines.
The Laryngoscope 2020 Wang N, Xu MJ, House AE, Strohl MP, Goldberg AN, Murr AH -
Head and neck surgery during the coronavirus-19 pandemic: The University of California San Francisco experience.
Head & neck 2020 Wai KC, Xu MJ, Lee RH, El-Sayed IH, George JR, Heaton CM, Knott PD, Park AM, Ryan WR, Seth R, Ha PK -
Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Glasbey JC, Nepogodiev D, Simoes JFF, Omar O, Li E, Venn ML, Abou Chaar MK, Capizzi V, Chaudhry D, Desai A, Edwards JG, Evans JP, Fiore M, Videria JF, Ford SJ, Ganly I, Griffiths EA, Gujjuri RR, … -
Delaying surgery for patients with a previous SARS-CoV-2 infection.
The British journal of surgery 2020 COVIDSurg Collaborative -
Challenges facing otolaryngologists in low- and middle-income countries during the COVID-19 pandemic.
International journal of pediatric otorhinolaryngology 2020 Kligerman MP, Lamour S, Okerosi S, Global OHNS Initiative -
Association of Ebola Virus Infection With Hearing Loss in Regions Where Ebola Virus Infection Is Endemic: A Systematic Review.
JAMA otolaryngology-- head & neck surgery 2019 Xu MJ, Stanford-Moore G, Czechowicz JA -
Cryoprobe retrieval of an airway foreign body: A case report and literature review.
International journal of pediatric otorhinolaryngology 2019 David AP, Xu MJ, Rosbe KW, Meyer AK, Gesthalter YB, Chan DK -
Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer.
The Laryngoscope 2019 Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR -
Squamous Cell Carcinoma of the Soft Palate in the United States: A Population-Based Study.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2018 Chan CK, Han AY, Alonso JE, Xu MJ, Mallen-St Clair J, Heaton CM, Ryan WR, Kuan EC, St John MA -
Oncologic and functional outcomes of pretreatment tracheotomy in advanced laryngeal squamous cell carcinoma: A multi-institutional analysis.
Oral oncology 2018 Byrd SA, Xu MJ, Cass LM, Wehrmann DJ, Naunheim M, Christopher K, Dombrowski JJ, Walker RJ, Wirth L, Clark J, Busse P, Chan A, Deschler DG, Emerick K, Lin DT, Varvares MA -
Outcomes of Low-Intensity Treatment of Acute Lymphoblastic Leukemia at Butaro Cancer Center of Excellence in Rwanda.
Journal of global oncology 2017 Rubagumya F, Xu MJ, May L, Driscoll C, Uwizeye FR, Shyirambere C, Larrabee K, Fehr AE, Gilbert UD, Muhayimana C, Hategekimana V, Elmore S, Mpunga T, Moore M, Shulman LN, Lehmann L -
EGFR-targeted therapies in the post-genomic era.
Cancer metastasis reviews 2017 Xu MJ, Johnson DE, Grandis JR -
Impact of Prior Unilateral Chest Wall Radiotherapy on Outcomes in Bilateral Breast Reconstruction.
Plastic and reconstructive surgery 2016 de Araujo TB, Jue Xu M, Susarla SM, Shmelev K, Jiang W, Pribaz JJ, Hergrueter C, Carty MJ, Caterson S, Chun YS -
Gestational Trophoblastic Neoplasia Treatment at the Butaro Cancer Center of Excellence in Rwanda.
Journal of global oncology 2016 Nzayisenga I, Segal R, Pritchett N, Xu MJ, Park PH, Mpanumusingo EV, Umuhizi DG, Goldstein DP, Berkowitz RS, Hategekimana V, Muhayimana C, Rubagumya F, Fadelu T, Tapela N, Mpunga T, Ghebre RG -
Pursuing equity in cancer care: implementation, challenges and preliminary findings of a public cancer referral center in rural Rwanda.
BMC cancer 2016 Tapela NM, Mpunga T, Hedt-Gauthier B, Moore M, Mpanumusingo E, Xu MJ, Nzayisenga I, Hategekimana V, Umuhizi DG, Pace LE, Bigirimana JB, Wang J, Driscoll C, Uwizeye FR, Drobac PC, Ngoga G, Shyirambere … -
Treating Nephroblastoma in Rwanda: Using International Society of Pediatric Oncology Guidelines in a Novel Oncologic Care Model.
Journal of global oncology 2016 Shyirambere C, Xu MJ, Elmore SN, Fadelu T, May L, Tapela N, Umuhizi DG, Uwizeye FR, Driscoll C, Muhayimana C, Hategekimana V, Rubagumya F, Nzayisenga I, Shulman LN, Mpunga T, Lehmann LE -
Creating and implementing low literacy cancer education materials: bridging the gap in sub-Saharan Africa.
Annals of Global Health 2015 M. Olsen, V.E. Manzo, C. Cardenas, A. Bhatt, A. Fajardo, F. Huang, M. Jacobs, S. Kennell-Heiling, L.S. May, H. Mehrtash, K. Taylor, M. Xu -
Students for global oncology: Building a movement for student education and engagement in an emerging field.
Annals of Global Health 2015 M. Vallurupalli, D.S. Shulman, S.N. Elmore, M. Xu, S. Dolisca, L. Ilcisin, A. Judd, T. Kolarova, J. Lock, N. Niu, M. Olsen, K. Taylor, H. Holmer, A. Bhatt, F. Huang -
Abstract LB-228: The identification of recurrent non-coding mutations in melanoma.
Molecular and Cellular Biology 2013 Franklin W. Huang, Eran Hodis, Mary Jue Xu, Gregory Kryukov, Lynda Chin, Levi A. Garraway -
Highly recurrent TERT promoter mutations in human melanoma.
Science (New York, N.Y.) 2013 Huang FW, Hodis E, Xu MJ, Kryukov GV, Chin L, Garraway LA -
Abstract 2973: Adhesion of tumor cells to ECM microarrays identifies novel ECM interactions in metastasis.
Tumor Biology 2012 Nathan E. Reticker-Flynn, David F. Braga Malta, Monte M. Winslow, Mary J. Xu, John M. Lamar, Richard O. Hynes, Tyler E. Jacks, Sangeeta N. Bhatia -
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.
Nature communications 2012 Reticker-Flynn NE, Malta DF, Winslow MM, Lamar JM, Xu MJ, Underhill GH, Hynes RO, Jacks TE, Bhatia SN -
Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A.
Biochimica et biophysica acta 2011 Wu CY, Curtis A, Choi YS, Maeda M, Xu MJ, Berg A, Joneja U, Mason RW, Lee KH, Wang W -
Cooperative nanomaterial system to sensitize, target, and treat tumors.
Proceedings of the National Academy of Sciences of the United States of America 2009 Park JH, von Maltzahn G, Xu MJ, Fogal V, Kotamraju VR, Ruoslahti E, Bhatia SN, Sailor MJ