Mary Gray, MD
Professor
Medicine
School of Medicine

I am Medical Director for Cardiology Clinical Services at San Francisco General Hospital. As inpatient Cardiology Service attending, I am responsible for individuals with acute coronary syndromes, heart failure exacerbations, heart rhythm disorders, endocarditis, and hypertensive emergencies.

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As inpatient Cardiology Consult attending, I coordinate complex care with Medicine, Family Medicine, Anesthesia, Neurology, Surgery Specialty, and Obstetrics Services. Echocardiography Laboratory and Cardiac Device Clinic duties encompass inpatients and outpatients. Cardiology Clinic and Anticoagulation Clinic duties include urgent evaluation prior to non-cardiac surgery and chronic management of diverse cardiovascular conditions. I respond to electronic requests (eConsults) for cardiology services from hospital areas, San Francisco Health Network clinics, and other healthcare facilities. I coordinate referrals to other UCSF campuses for cardiac electrophysiology, cardiothoracic surgery, and stress imaging procedures. I am Chair of the ZSFG Medication Error Reduction Plan Committee. I am Associate Medical Director for ZSFG Risk Management.

Education & Training

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• B.A.S. Biology and English Stanford University
• Chief Medicine Resident UC San Diego Dept of Medicine
• Medicine Resident UC San Diego Dept of Medicine
• M.D. Medical Student UC San Diego School of Medicine
• Clinical Cardiology Fellow UC San Francisco
• Postdoctoral Research Fellow UC San Francisco

Grants and Projects

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• Cigarette Smoke and Alcohol-Induced Heart Injury, NIH, 2008-2012
• Mechanisms of Cardioprotection in Ischemia and Failure, NIH, 2002-2008
• Protection From Cardiac Reperfusion Injury by Ethanol, NIH, 1996-2008

Publications (9)

Top publication keywords:
Mitochondria, HeartMyocardial Reperfusion InjuryReceptors, LysosphingolipidIsoenzymesMyocardiumCreatine KinaseProtein Kinase CGTP-Binding Protein alpha Subunits, Gi-GoIschemic Preconditioning, MyocardialG(M1) GangliosidePoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-aktElectron TransportSphingosineMyocardial Reperfusion

• Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies.
  Alcoholism, clinical and experimental research 2008 Collins MA, Neafsey EJ, Mukamal KJ, Gray MO, Parks DA, Das DK, Korthuis RJ
• Signals from type 1 sphingosine 1-phosphate receptors enhance adult mouse cardiac myocyte survival during hypoxia.
  American journal of physiology. Heart and circulatory physiology 2007 Zhang J, Honbo N, Goetzl EJ, Chatterjee K, Karliner JS, Gray MO
• Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction.
  Biochemical and biophysical research communications 2007 Zhou HZ, Ma X, Gray MO, Zhu BQ, Nguyen AP, Baker AJ, Simonis U, Cecchini G, Lovett DH, Karliner JS
• Poly(ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts.
  American journal of physiology. Heart and circulatory physiology 2006 Zhou HZ, Swanson RA, Simonis U, Ma X, Cecchini G, Gray MO
• MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury.
  American journal of physiology. Heart and circulatory physiology 2005 Jin ZQ, Zhou HZ, Cecchini G, Gray MO, Karliner JS

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• Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
  The Journal of biological chemistry 2003 Gray MO, Zhou HZ, Schafhalter-Zoppoth I, Zhu P, Mochly-Rosen D, Messing RO
• Effect of anoxia/reperfusion on the reversible active/de-active transition of NADH-ubiquinone oxidoreductase (complex I) in rat heart.
  Biochimica et biophysica acta 2002 Maklashina E, Sher Y, Zhou HZ, Gray MO, Karliner JS, Cecchini G
• Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.
  American journal of physiology. Heart and circulatory physiology 2002 Zhou HZ, Karliner JS, Gray MO
• Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.
  American journal of physiology. Heart and circulatory physiology 2002 Jin ZQ, Zhou HZ, Zhu P, Honbo N, Mochly-Rosen D, Messing RO, Goetzl EJ, Karliner JS, Gray MO