Marko Groeger, PhD
Postdoctoral Scholar
Surgery
School of Medicine

Education & Training

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• PhD Molecular Medicine University Hospital Jena 2018
• Diploma Trophology Friedrich Schiller University Jena 2013

Interests

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• iPSC derived hepatocytes
• organ-on-chip & microphysiological systems
• inflammation
• liver disease
• immunology

Publications (7)

Top publication keywords:
Lab-On-A-Chip DevicesLiverOrgan Preservation SolutionsMonocytesInduced Pluripotent Stem CellsDiabetes Mellitus, Type 2InflammationInsulin ResistanceHepatocytesChemokine CX3CL1OrganoidsEndothelial CellsLipopolysaccharidesInsulinsModels, Biological

• Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system.
  Nature communications 2024 Qi L, Groeger M, Sharma A, Goswami I, Chen E, Zhong F, Ram A, Healy K, Hsiao EC, Willenbring H, Stahl A
• Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages.
  Nature communications 2023 Groeger M, Matsuo K, Heidary Arash E, Pereira A, Le Guillou D, Pino C, Telles-Silva KA, Maher JJ, Hsiao EC, Willenbring H
• Preservation of Cell Structure, Metabolism, and Biotransformation Activity of Liver-On-Chip Organ Models by Hypothermic Storage.
  Advanced healthcare materials 2017 Gröger M, Dinger J, Kiehntopf M, Peters FT, Rauen U, Mosig AS
• Recruitment of CD16(+) monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine.
  Cytokine 2016 Rennert K, Heisig K, Groeger M, Wallert M, Funke H, Lorkowski S, Huber O, Mosig AS
• Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.
  Scientific reports 2016 Gröger M, Rennert K, Giszas B, Weiß E, Dinger J, Funke H, Kiehntopf M, Peters FT, Lupp A, Bauer M, Claus RA, Huber O, Mosig AS
• A new fluorescent dye for cell tracing and mitochondrial imaging in vitro and in vivo.
  Journal of biophotonics 2015 Press AT, Ungelenk L, Rinkenauer AC, Gröger M, Lehmann F, Mosig A, Schubert US, Clemens MG, Bauer M
• A microfluidically perfused three dimensional human liver model.
  Biomaterials 2015 Rennert K, Steinborn S, Gröger M, Ungerböck B, Jank AM, Ehgartner J, Nietzsche S, Dinger J, Kiehntopf M, Funke H, Peters FT, Lupp A, Gärtner C, Mayr T, Bauer M, Huber O, Mosig AS