Mark Von Zastrow, MD, PhD
Professor
Psychiatry
School of Medicine

Websites

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• Profile at UCSF Department of Psychiatry (psych.ucsf.edu)

Grants and Projects

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• Mechanisms Regulating Endocytosis of Opioid Receptors, NIH, 1999-2021
• Membrane Trafficking of Opioid and Adrenergic Receptors, NIH, 1997-2019
• Presynaptic Mechanisms of Neural Plasticity, NIH, 1995-2018
• Bio-Organic Biomedical Mass Spectrometry Resource, NIH, 1982-2015
• Membrane Trafficking of Opioid Receptors, NIH, 1997-2014
• Receptors and Second Messengers for Pain and Analgesia, NIH, 2007-2013
• Post-endocytic Sorting of Opioid Receptors, NIH, 1999-2010
• 2007 Molecular Pharmacology Gordon Research Conference, NIH, 2007
• Extracellular Matrix Protein enhancement of Phagocytosis, NIH, 1986-2007
• Membrane Trafficking of Opioid Receptors, NIH, 1997-2004
• Mechanisms of Receptor Internalization in Drug Addiction, NIH, 1994-1999

Publications (18)

Top publication keywords:
EndosomesNarcoticsProtein TransportProtein BiosynthesisReceptors, Adrenergic, beta-2Cyclic AMPNeuronsClass III Phosphatidylinositol 3-KinasesReceptors, OpioidPhosphatidylinositol PhosphatesCell MembraneNeurotransmitter AgentsEndocytosisHEK293 CellsSignal Transduction

• A High-throughput CRISPR Interference Screen to Dissect Functional Regulators of GPCR/cAMP Signaling.
  The FASEB Journal 2020 Khairunnisa Mentari Semesta, Ruilin Tian, Martin Kampmann, Mark von Zastrow, Nikoleta G. Tsvetanova
• Chemical Biology Approaches for Genome-Wide Screening of GPCR Trafficking.
  The FASEB Journal 2020 Braden Lobingier, Nikoleta Tsvetanova, Mark von Zastrow
• Endosomal Phosphatidylinositol 3-Kinase Is Essential for Canonical GPCR Signaling.
  Molecular pharmacology 2016 Uchida Y, Rutaganira FU, Jullié D, Shokat KM, von Zastrow M
• Modulating neuromodulation by receptor membrane traffic in the endocytic pathway.
  Neuron 2012 von Zastrow M, Williams JT
• Science Signaling Podcast: 9 August 2011.
  Science Signaling 2011 Mark von Zastrow, Annalisa M. VanHook

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• Opioid Receptor Trafficking.
  The Opiate Receptors 2011 Mark von Zastrow
• Membrane traffic in the post-genomic era.
  Genome Biology 2010 Peter Hein, Mark von Zastrow
• Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications.
  Drug and alcohol dependence 2010 von Zastrow M
• Chapter 27 Agonist-Induced Desensitization and Endocytosis of G-protein-Coupled Receptors.
  Handbook of Cell Signaling 2010 Michael Tanowitz, Mark von Zastrow
• Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions.
  Cell 2008 Robin M. Shaw, Alex J. Fay, Manojkumar A. Puthenveedu, Mark von Zastrow, Yuh-Nung Jan, Lily Y. Jan
• Signaling on the endocytic pathway.
  Current opinion in cell biology 2007 von Zastrow M, Sorkin A
• Endocytosis.
  Encyclopedia of Molecular Cell Biology and Molecular Medicine 2006 Hadiya A. Watson, Mark Von Zastrow, Beverly Wendland
• Regulated Membrane Trafficking and Proteolysis of GPCRs.
  The G Protein-Coupled Receptors Handbook 2005 James N. Hislop, Mark von Zastrow
• Identification of Protein Interactions by Yeast Two-Hybrid Screening and Coimmunoprecipitation.
  Receptor Signal Transduction Protocols 2004 Michael Tanowitz, Mark von Zastrow
• A walk on the wild side (of the synapse).
  Nature Cell Biology 2003 Mark von Zastrow
• Chapter 31 Agonist-Induced Desensitization and Endocytosis of G-Protein-Coupled Receptors.
  Handbook of Cell Signaling 2003 Mark von Zastrow
• Intracellular trafficking of epitope-tagged opioid receptors: Different effects of morphine and enkephalin.
  Peptides 1994 M von Zastrow, D Keith, P Zaki, C Evans
• An approach to the molecular biology of opiate tolerance: identification of opiate-regulated transcripts.
  NIDA research monograph 1991 vonZastrow M, Barchas JD, Eberwine JH