Mark Ryder, DMD
Professor
Orofacial Sciences
School of Dentistry

Publications (93)

Top publication keywords:
PeriodontiumDental CementumPeriodontitisTobacco ProductsBacteroidaceae InfectionsPeriodontal LigamentTobacco Use CessationPorphyromonas gingivalisPeriodontal DiseasesPeriodonticsNeutrophilsToothSmokeMouth DiseasesSaliva

• Geroscience: Aging and Oral Health Research.
  Advances in dental research 2023 Weintraub JA, Kaeberlein M, Perissinotto C, Atchison KA, Chen X, D'Souza RN, Feine JS, Ghezzi EM, Kirkwood KL, Ryder M, Slashcheva LD, Touger-Decker R, Wu B, Kapila Y
• The Link Between Periodontitis and Alzheimer’s Disease: Reality or Yet Another Association.
  Current Oral Health Reports 2022 Mark I. Ryder
• Functional Adaptation of LPS-affected Dentoalveolar Fibrous Joints in Rats.
  Journal of periodontal research 2021 Wang B, Ustriyana P, Tam CS, Lin JD, Srirangapatanam S, Kapila Y, Ryder MI, Webb S, Seo Y, Ho SP
• Alzheimer disease and the periodontal patient: New insights, connections, and therapies.
  Periodontology 2000 2021 Ryder MI, Xenoudi P
• Salivary metabolite levels in perinatally HIV-infected youth with periodontal disease.
  Metabolomics : Official journal of the Metabolomic Society 2020 Schulte F, King OD, Paster BJ, Moscicki AB, Yao TJ, Van Dyke RB, Shiboski C, Ryder M, Seage G, Hardt M, Pediatric HIV/AIDS Cohort Study

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• Porphyromonas gingivalis and Alzheimer disease: Recent findings and potential therapies.
  Journal of periodontology 2020 Ryder MI
• COR388 for the Treatment of Alzheimer’s Disease (4098).
  Neurology 2020 Michael Detke, Casey Lynch, Leslie Holsinger, Shirin Kapur, Dave Hennings, Debasish Raha, Sean Broce, Mai Nguyen, Florian Ermini, Ursula Haditsch, Mark Ryder, Ira Goodman, Stephen Thein, Stephen …
• Biomechanical pathways of dentoalveolar fibrous joints in health and disease.
  Periodontology 2000 2020 Lin JD, Ryder M, Kang M, Ho SP
• Current trends and new developments in HIV research and periodontal diseases.
  Periodontology 2000 2020 Ryder MI, Shiboski C, Yao TJ, Moscicki AB
• Microbial biogeography and ecology of the mouth and implications for periodontal diseases.
  Periodontology 2000 2020 Proctor DM, Shelef KM, Gonzalez A, Davis CL, Dethlefsen L, Burns AR, Loomer PM, Armitage GC, Ryder MI, Millman ME, Knight R, Holmes SP, Relman DA
• Periodontics in the USA: An introduction.
  Periodontology 2000 2020 Ryder MI
• Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388.
  Pharmacology research & perspectives 2020 Arastu-Kapur S, Nguyen M, Raha D, Ermini F, Haditsch U, Araujo J, De Lannoy IAM, Ryder MI, Dominy SS, Lynch C, Holsinger LJ
• Nonsurgical Periodontal Therapy in CKD: Findings of the Kidney and Periodontal Disease (KAPD) Pilot Randomized Controlled Trial.
  Kidney medicine 2019 Grubbs V, Garcia F, Vittinghoff E, Jue BL, Ryder M, Lovett DH, Offenbacher S, Taylor G, Ganz P, Bibbins-Domingo K, Powe NR
• Biomarkers of oral inflammation in perinatally HIV-infected and perinatally HIV-exposed, uninfected youth.
  Journal of clinical periodontology 2019 Moscicki AB, Yao TJ, Russell JS, Farhat S, Scott M, Magpantay L, Halec G, Shiboski CH, Ryder MI, Pediatric HIV/AIDS Cohort Study
• INITIATION OF THE PHASE 2/3 GAIN TRIAL OF COR388, A NOVEL BACTERIAL VIRULENCE FACTOR INHIBITOR FOR THE TREATMENT OF ALZHEIMER’S DISEASE (AD) BASED ON PHASE I A/B SAFETY, PK, BIOMARKER AND EFFICACY DATA.
  Alzheimer's & Dementia 2019 Mike Detke, Casey Lynch, Leslie Holsinger, Shirin Kapur, Dave Hennings, Debasish Raha, Florian Ermini, Ursula Haditsch, Mark Ryder, Ira J. Goodman, Stephen G. Thein, Steve Dominy
• Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.
  Science advances 2019 Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz…
• The association between oral disease and type of antiretroviral therapy among perinatally HIV-infected youth.
  AIDS (London, England) 2018 Shiboski CH, Yao TJ, Russell JS, Ryder MI, Van Dyke RB, Seage GR, Moscicki AB, Pediatric HIV/AIDS Cohort Study
• Personalized periodontal treatment for the tobacco- and alcohol-using patient.
  Periodontology 2000 2018 Ryder MI, Couch ET, Chaffee BW
• Oral microbiota in youth with perinatally acquired HIV infection.
  Microbiome 2018 Starr JR, Huang Y, Lee KH, Murphy CM, Moscicki AB, Shiboski CH, Ryder MI, Yao TJ, Faller LL, Van Dyke RB, Paster BJ, Pediatric HIV/AIDS Cohort Study
• Advanced platelet-rich fibrin and freeze-dried bone allograft for ridge preservation: A randomized controlled clinical trial.
  Journal of periodontology 2018 Clark D, Rajendran Y, Paydar S, Ho S, Cox D, Ryder M, Dollard J, Kao RT
• A spatial gradient of bacterial diversity in the human oral cavity shaped by salivary flow.
  Nature communications 2018 Proctor DM, Fukuyama JA, Loomer PM, Armitage GC, Lee SA, Davis NM, Ryder MI, Holmes SP, Relman DA
• A Force on the Crown and Tug of War in the Periodontal Complex.
  Journal of dental research 2018 Jang AT, Chen L, Shimotake AR, Landis W, Altoe V, Aloni S, Ryder M, Ho SP
• The Kidney and Periodontal Disease (KAPD) study: A pilot randomized controlled trial testing the effect of non-surgical periodontal therapy on chronic kidney disease.
  Contemporary clinical trials 2016 Grubbs V, Garcia F, Jue BL, Vittinghoff E, Ryder M, Lovett D, Carrillo J, Offenbacher S, Ganz P, Bibbins-Domingo K, Powe NR
• Prevalence of periodontal diseases in a multicenter cohort of perinatally HIV-infected and HIV-exposed and uninfected youth.
  Journal of clinical periodontology 2016 Ryder MI, Yao TJ, Russell JS, Moscicki AB, Shiboski CH, Pediatric HIV/AIDS Cohort Study
• Oral Human Papillomavirus in Youth From the Pediatric HIV/AIDS Cohort Study.
  Sexually transmitted diseases 2016 Moscicki AB, Farhat S, Yao TJ, Ryder MI, Russell JS, Van Dyke RB, Hazra R, Shiboski CH, Pediatric HIVAIDS Cohort Study
• The Burden of Oral Disease among Perinatally HIV-Infected and HIV-Exposed Uninfected Youth.
  PloS one 2016 Moscicki AB, Yao TJ, Ryder MI, Russell JS, Dominy SS, Patel K, McKenna M, Van Dyke RB, Seage GR, Hazra R, Shiboski
• Minimally invasive periodontal therapy for general practitioners.
  Periodontology 2000 2016 Ryder MI, Armitage GC
• The tobacco-using periodontal patient: role of the dental practitioner in tobacco cessation and periodontal disease management.
  Periodontology 2000 2016 Chaffee BW, Couch ET, Ryder MI
• Strain-guided mineralization in the bone-PDL-cementum complex of a rat periodontium.
  Bone reports 2015 Grandfield K, Herber RP, Chen L, Djomehri S, Tam C, Lee JH, Brown E, Woolwine WR, Curtis D, Ryder M, Schuck J, Webb S, Landis W, Ho S
• Aging Periodontium, Aging Patient: Current Concepts.
  Journal of the California Dental Association 2015 Ryder M
• Differentiating zones at periodontal ligament-bone and periodontal ligament-cementum entheses.
  Journal of periodontal research 2015 Lee JH, Pryce BA, Schweitzer R, Ryder MI, Ho SP
• Adaptive properties of human cementum and cementum dentin junction with age.
  Journal of the mechanical behavior of biomedical materials 2014 Jang AT, Lin JD, Choi RM, Choi EM, Seto ML, Ryder MI, Gansky SA, Curtis DA, Ho SP
• Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota.
  Scientific reports 2014 Arimatsu K, Yamada H, Miyazawa H, Minagawa T, Nakajima M, Ryder MI, Gotoh K, Motooka D, Nakamura S, Iida T, Yamazaki K
• Proteomic analysis of saliva in HIV-positive heroin addicts reveals proteins correlated with cognition.
  PloS one 2014 Dominy SS, Brown JN, Ryder MI, Gritsenko M, Jacobs JM, Smith RD
• The plastic nature of the human bone-periodontal ligament-tooth fibrous joint.
  Bone 2013 Ho SP, Kurylo MP, Grandfield K, Hurng J, Herber RP, Ryder MI, Altoe V, Aloni S, Feng JQ, Webb S, Marshall GW, Curtis D, Andrews JC, Pianetta P
• The adaptive nature of the bone-periodontal ligament-cementum complex in a ligature-induced periodontitis rat model.
  BioMed research international 2013 Lee JH, Lin JD, Fong JI, Ryder MI, Ho SP
• Periodontal disease in HIV/AIDS.
  Periodontology 2000 2012 Ryder MI, Nittayananta W, Coogan M, Greenspan D, Greenspan JS
• Elastic discontinuity due to ectopic calcification in a human fibrous joint.
  Acta biomaterialia 2012 Lin JD, Aloni S, Altoe V, Webb SM, Ryder MI, Ho SP
• Age-related adaptation of bone-PDL-tooth complex: Rattus-Norvegicus as a model system.
  PloS one 2012 Leong NL, Hurng JM, Djomehri SI, Gansky SA, Ryder MI, Ho SP
• Reduced functional loads alter the physical characteristics of the bone-periodontal ligament-cementum complex.
  Journal of periodontal research 2011 Niver EL, Leong N, Greene J, Curtis D, Ryder MI, Ho SP
• Discontinuities in the human bone-PDL-cementum complex.
  Biomaterials 2011 Hurng JM, Kurylo MP, Marshall GW, Webb SM, Ryder MI, Ho SP
• Current challenges for dental education in Japan and the United States.
  Japanese Dental Science Review 2011 Mark I. Ryder, Ikuko Morio
• The biomechanical characteristics of the bone-periodontal ligament-cementum complex.
  Biomaterials 2010 Ho SP, Kurylo MP, Fong TK, Lee SS, Wagner HD, Ryder MI, Marshall GW
• Comparison of neutrophil functions in aggressive and chronic periodontitis.
  Periodontology 2000 2010 Ryder MI
• Concepts, controversies, consensus, and conclusions: preface.
  Periodontology 2000 2009 Ryder MI
• Evolution and revolution: the curriculum reform process at UCSF.
  Journal of dental education 2008 Ryder MI, Sargent P, Perry D
• Structure, chemical composition and mechanical properties of human and rat cementum and its interface with root dentin.
  Acta biomaterialia 2008 Ho SP, Yu B, Yun W, Marshall GW, Ryder MI, Marshall SJ
• The tooth attachment mechanism defined by structure, chemical composition and mechanical properties of collagen fibers in the periodontium.
  Biomaterials 2007 Ho SP, Marshall SJ, Ryder MI, Marshall GW
• The influence of smoking on host responses in periodontal infections.
  Periodontology 2000 2007 Ryder MI
• Alteration of gene expression profiles of peripheral mononuclear blood cells by tobacco smoke: implications for periodontal diseases.
  Oral microbiology and immunology 2004 Ryder MI, Hyun W, Loomer P, Haqq C
• Risk assessment in clinical practice.
  Periodontology 2000 2004 Ronderos M, Ryder MI
• Effects of tobacco smoke on the secretion of interleukin-1beta, tumor necrosis factor-alpha, and transforming growth factor-beta from peripheral blood mononuclear cells.
  Oral microbiology and immunology 2002 Ryder MI, Saghizadeh M, Ding Y, Nguyen N, Soskolne A
• Alterations of neutrophil f-actin kinetics by tobacco smoke: implications for periodontal diseases.
  Journal of periodontal research 2002 Ryder MI, Wu TC, Kallaos SS, Hyun W
• The effects of subgingival calculus on the clinical outcomes of locally-delivered controlled-release doxycycline compared to scaling and root planing.
  Journal of clinical periodontology 2002 Johnson LR, Stoller NH, Polson A, Harrold CQ, Ryder M, Garrett S
• The significance of prior mechanical therapy for changes of periodontal status achieved by local delivery of a doxycyclinehyclate containing gel.
  Journal Of Clinical Periodontology 2001 Lawrence E. Wolinsky, Paulo M. Camargo, Alan Polson, Mark Ryder, Steven Garrett
• The significance of prior mechanical therapy for changes of periodontal status achieved by local delivery of a doxycyclinehyclate containing gel.
  Journal of clinical periodontology 2001 Wolinsky LE, Camargo PM, Polson A, Ryder M, Garrett S
• An economic evaluation of a chlorhexidine chip for treating chronic periodontitis: the CHIP (chlorhexidine in periodontitis) study.
  Journal of the American Dental Association (1939) 2001 Henke CJ, Villa KF, Aichelmann-Reidy ME, Armitage GC, Eber RM, Genco RJ, Killoy WJ, Miller DP, Page RC, Polson AM, Ryder MI, Silva SJ, Somerman MJ, Van Dyke TE, Wolff LF, Evans CJ, Finkelman RD
• Safety of once-weekly alendronate 70 mg in the treatment of periodontal disease.
  The American Journal of Gastroenterology 2000 Thomas Dyke Van, Mark Ryder, Rafael Cordero, Andrew Gallagher, Garth R Griffiths, Steven Offenbacher, Giovanni Cizza, Weichung Shih, Mary Kimberlin, Lei Meng, Antonio Lombardi
• Periodontal management of HIV-infected patients.
  Periodontology 2000 2000 Ryder MI
• The effect of locally delivered controlled-release doxycycline or scaling and root planing on periodontal maintenance patients over 9 months.
  Journal of periodontology 2000 Garrett S, Adams DF, Bogle G, Donly K, Drisko CH, Hallmon WW, Hancock EB, Hanes P, Hawley CE, Johnson L, Kiger R, Killoy W, Mellonig JT, Raab FJ, Ryder M, Stoller N, Polson A, Wang HL, Wolinsky LE, …
• Cysteine protease inhibitory activity and levels of salivary cystatins in whole saliva of periodontally diseased patients.
  Journal of periodontal research 1999 Baron AC, Gansky SA, Ryder MI, Featherstone JD
• Effects of smoking on local delivery of controlled-release doxycycline as compared to scaling and root planing.
  Journal of clinical periodontology 1999 Ryder MI, Pons B, Adams D, Beiswanger B, Blanco V, Bogle G, Donly K, Hallmon W, Hancock EB, Hanes P, Hawley C, Johnson L, Wang HL, Wolinsky L, Yukna R, Polson A, Carron G, Garrett S
• Two multi-center studies evaluating locally delivered doxycycline hyclate, placebo control, oral hygiene, and scaling and root planing in the treatment of periodontitis.
  Journal of periodontology 1999 Garrett S, Johnson L, Drisko CH, Adams DF, Bandt C, Beiswanger B, Bogle G, Donly K, Hallmon WW, Hancock EB, Hanes P, Hawley CE, Kiger R, Killoy W, Mellonig JT, Polson A, Raab FJ, Ryder M, Stoller NH, …
• Alterations of neutrophil L-selectin and CD18 expression by tobacco smoke: implications for periodontal diseases.
  Journal of periodontal research 1998 Ryder MI, Fujitaki R, Lebus S, Mahboub M, Faia B, Muhaimin D, Hamada M, Hyun W
• Alterations of neutrophil oxidative burst by in vitro smoke exposure: implications for oral and systemic diseases.
  Annals of periodontology 1998 Ryder MI, Fujitaki R, Johnson G, Hyun W
• Alterations of neutrophil l-selectin and CD18 expression by tobacco smoke: implications for periodontal diseases.
  Journal of Periodontal Research 1998 Mark I. Ryder, Ron Fujitaki, Scott Lebus, Mahyar Mahboub, Brandi Faia, Dawud Muhaimin, Makoto Hamada, William Hyun
• The use of polylactic acid polymers in local drug delivery and guided tissue regeneration (at Nihon University School of Dentistry on November 12, 1996).
  The Journal of Nihon University School of Dentistry 1997 Ryder MI
• Nicotine effects on neutrophil F-actin formation and calcium release: implications for tobacco use and pulmonary diseases.
  Experimental lung research 1994 Ryder MI
• Phagocytic function of polymorphonuclear leucocytes in the oral cavity.
  Journal of Oral Biosciences 1994 Yukihiro Numabe, Kohichi Kiyonobu, Mark I Ryder, Kyuichi Kamoi
• Epithelial cell kinetics with atelocollagen membranes: a study in rats.
  Journal of periodontology 1993 Numabe Y, Ito H, Hayashi H, Ryder MI, Kamoi K
• Periodontal considerations in the patient with HIV.
  Current opinion in periodontology 1993 Ryder MI
• Keratin expression in cultures of adult human epidermal cells.
  Cellular and molecular biology 1991 Chandrakasan G, Hwang CB, Ryder M, Bhatnagar RS
• Cytokeratin patterns in corneal, limbal, and conjunctival epithelium. An immunofluorescence study with PKK-1, 8.12, 8.60, and 4.62 anticytokeratin antibodies.
  Investigative ophthalmology & visual science 1990 Ryder MI, Weinreb RN
• In situ localization of cytoskeletal elements in the human trabecular meshwork and cornea.
  Investigative ophthalmology & visual science 1990 Weinreb RN, Ryder MI
• Ammonia as a potential mediator of adult human periodontal infection: inhibition of neutrophil function.
  Archives of oral biology 1990 Niederman R, Brunkhorst B, Smith S, Weinreb RN, Ryder MI
• Microtubule-granule relationships in motile human polymorphonuclear leukocytes.
  The Anatomical record 1988 Ryder MI, Weinreb RN, Niederman R
• Quantitative assessment of cynomolgus monkey trabecular cell phagocytosis and adsorption.
  Current eye research 1988 Barak MH, Weinreb RN, Ryder MI
• The cytoskeleton of the cultured human trabecular cell. Characterization and drug responses.
  Investigative ophthalmology & visual science 1988 Ryder MI, Weinreb RN, Alvarado J, Polansky J
• Elevated phagocytosis, oxidative burst, and F-actin formation in PMNs from individuals with intraoral manifestations of HIV infection.
  Journal of acquired immune deficiency syndromes 1988 Ryder MI, Winkler JR, Weinreb RN
• Diagnostic Testing in Ophthalmic Sarcoidosis.
  Seminars in Ophthalmology 1987 Robert N. Weinreb, Barry K. Lipson, Mark I. Ryder, William Freeman
• The cytoskeleton of the cynomolgus monkey trabecular cell. I. General considerations.
  Investigative ophthalmology & visual science 1986 Ryder MI, Weinreb RN
• The cytoskeleton of the cynomolgus monkey trabecular cell. II. Influence of cytoskeleton-active drugs.
  Investigative ophthalmology & visual science 1986 Weinreb RN, Ryder MI, Polansky JR
• Angiotensin-converting enzyme activity in human aqueous humor.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1985 Weinreb RN, Sandman R, Ryder MI, Friberg TR
• Bactericidal action of bicarbonate ion on selected periodontal pathogenic microorganisms.
  Journal of periodontology 1984 Newbrun E, Hoover CI, Ryder MI
• The organization of actin filaments in human polymorphonuclear leukocytes.
  The Anatomical record 1984 Ryder MI, Weinreb RN, Niederman R
• Cemental changes in teeth with heavily infected root canals.
  Journal of endodontics 1983 Armitage GC, Ryder MI, Wilcox SE
• The cortical actin networks of migrating human PMNs.
  Journal of periodontal research 1982 Niederman R, Ryder MI, Horton JE, Sullivan T, Peters L, Hartwig J, Stossel TP
• The cytoskeleton of human polymorphonuclear leukocytes: phagocytosis and degranulation.
  The Anatomical record 1982 Ryder MI, Niederman R, Taggart EJ
• The adherence to bone by cytoplasmic elements of osteoclast.
  Journal of dental research 1981 Ryder MI, Jenkins SD, Horton JE
• Histological and ultrastructural characteristics of the periodontal syndrome in the rice rat. IV. The effects of dietary antibiotics on the histological and ultrastructural characteristics of periodontal syndrome susceptible rats.
  Journal of periodontal research 1981 Ryder MI
• Histological and ultrastructural characteristics of the periodontal syndrome in the rice rat. II. Ultrastructural observations on changes in the gingival sulcus, gingival epithelium and lamina propria.
  Journal of periodontal research 1980 Ryder MI
• Histological and ultrastructural characteristics of the periodontal syndrome in the rice rat. III. Ultrastructural observations on changes in the transseptal fiber area and alveolar crest.
  Journal of periodontal research 1980 Ryder MI
• Histological and ultrastructural characteristics of the periodontal syndrome in the rice rat. I. General light microscopic observations and ultrastructural observations of initial inflammatory changes.
  Journal of periodontal research 1980 Ryder MI