Mark Ratcliffe, MD
Professor
Surgery
School of Medicine

Grants and Projects

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• Quantitative analysis of left ventriculoplasty: CHF, NIH, 2000-2020
• Surgery for Ischemic Mitral Regurgitation, NIH, 2008-2013

Publications (122)

Top publication keywords:
Ventricular Function, LeftMagnetic Resonance Imaging, CineSheepMitral ValveMitral Valve InsufficiencyHeart VentriclesCardiac Surgical ProceduresVentricular RemodelingFinite Element AnalysisHeart AneurysmMyocardial ContractionMitral Valve AnnuloplastyCardiomyopathy, DilatedModels, CardiovascularMyocardial Infarction

• Imaging in Pulmonary Vascular Disease-Understanding Right Ventricle-Pulmonary Artery Coupling.
  Comprehensive Physiology 2022 Tsarova K, Morgan AE, Melendres-Groves L, Ibrahim MM, Ma CL, Pan IZ, Hatton ND, Beck EM, Ferrel MN, Selzman CH, Ingram D, Alamri AK, Ratcliffe MB, Wilson BD, Ryan JJ
• All Roads Lead to Rome: Diverse Etiologies of Tricuspid Regurgitation Create a Predictable Constellation of Right Ventricular Shape Changes.
  Frontiers in physiology 2022 Orkild BA, Zenger B, Iyer K, Rupp LC, Ibrahim MM, Khashani AG, Perez MD, Foote MD, Bergquist JA, Morris AK, Kim JJ, Steinberg BA, Selzman C, Ratcliffe MB, MacLeod RS, Elhabian S, Morgan AE
• A finite element model of the cardiac ventricles with coupled circulation: Biventricular mesh generation with hexahedral elements, airbags and a functional mockup interface to the circulation.
  Computers in biology and medicine 2021 Zhang Y, Adams J, Wang VY, Horwitz L, Tartibi M, Morgan AE, Kim J, Wallace AW, Weinsaft JW, Ge L, Ratcliffe MB
• A kinematic model-based analysis framework for 3D Cine-DENSE-validation with an axially compressed gel phantom and application in sheep before and after antero-apical myocardial infarction.
  Magnetic resonance in medicine 2021 Wang VY, Tartibi M, Zhang Y, Selvaganesan K, Haraldsson H, Auger DA, Faraji F, Spaulding K, Takaba K, Collins A, Aguayo E, Saloner D, Wallace AW, Weinsaft JW, Epstein FH, Guccione J, Ge L, Ratcliffe …
• Finite-element based optimization of left ventricular passive stiffness in normal volunteers and patients after myocardial infarction: Utility of an inverse deformation gradient calculation of regional diastolic strain.
  Journal of the mechanical behavior of biomedical materials 2021 Zhang Y, Wang VY, Morgan AE, Kim J, Tafreshi R, Wallace AW, Guccione JM, Weinsaft JW, Ge L, Ratcliffe MB

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• Ischemia-Mediated Dysfunction in Subpapillary Myocardium as a Marker of Functional Mitral Regurgitation.
  JACC. Cardiovascular imaging 2021 Kochav JD, Kim J, Judd R, Kim HW, Klem I, Heitner J, Shah D, Shenoy C, Farzaneh-Far A, Polsani V, Kalil R, Villar-Calle P, Nambiar L, Sultana R, Parker M, Cargile P, Khalique OK, Leon MB, Karmpaliotis…
• Right Ventricular Shape Distortion in Tricuspid Regurgitation.
  Computing in cardiology 2021 Morgan AE, Kashani A, Zenger B, Rupp LC, Perez MD, Foote MD, Morris AK, Ratcliffe MB, Kim JJ, Weinsaft JW, Sharma V, MacLeod RS, Elhabian S
• Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep.
  PloS one 2020 Giao DM, Wang Y, Rojas R, Takaba K, Badathala A, Spaulding KA, Soon G, Zhang Y, Wang VY, Haraldsson H, Liu J, Saloner D, Guccione JM, Ge L, Wallace AW, Ratcliffe MB
• Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility.
  Journal of biomedical materials research. Part A 2020 Spaulding KA, Zhu Y, Takaba K, Ramasubramanian A, Badathala A, Haraldsson H, Collins A, Aguayo E, Shah C, Wallace AW, Ziats NP, Lovett DH, Baker AJ, Healy KE, Ratcliffe MB
• A Novel MRI-Based Finite Element Modeling Method for Calculation of Myocardial Ischemia Effect in Patients With Functional Mitral Regurgitation.
  Frontiers in physiology 2020 Zhang Y, Wang VY, Morgan AE, Kim J, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB
• Transcatheter MitraClip repair alters mitral annular geometry - device induced annular remodeling on three-dimensional echocardiography predicts therapeutic response.
  Cardiovascular ultrasound 2019 Kim J, Palumbo MC, Khalique OK, Rong LQ, Sultana R, Das M, Jantz J, Nagata Y, Devereux RB, Wong SC, Bergman GW, Levine RA, Ratcliffe MB, Weinsaft JW
• Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation - A finite element modeling study.
  PloS one 2019 Zhang Y, Wang VY, Morgan AE, Kim J, Handschumacher MD, Moskowitz CS, Levine RA, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB
• Impact of Mitral Regurgitation Severity and Cause on Effort Tolerance-Integrated Stress Myocardial Perfusion Imaging and Echocardiographic Assessment of Patients With Known or Suspected Coronary Artery Disease Undergoing Exercise Treadmill Testing.
  Journal of the American Heart Association 2019 Kampaktsis PN, Albert BJ, Kim J, Xie LX, Brouwer LR, Tehrani NH, Villanueva M, Choi DY, Szulc M, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW
• Left ventricular geometry predicts optimal response to percutaneous mitral repair via MitraClip: Integrated assessment by two- and three-dimensional echocardiography.
  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2019 Kim J, Alakbarli J, Palumbo MC, Xie LX, Rong LQ, Tehrani NH, Brouwer LR, Devereux RB, Wong SC, Bergman GW, Khalique OK, Levine RA, Ratcliffe MB, Weinsaft JW
• Tissue-based markers of right ventricular dysfunction in ischemic mitral regurgitation assessed via stress cardiac magnetic resonance and three-dimensional echocardiography.
  The international journal of cardiovascular imaging 2018 Kim J, Alakbarli J, Yum B, Tehrani NH, Pollie MP, Abouzeid C, Di Franco A, Ratcliffe MB, Poppas A, Levine RA, Devereux RB, Weinsaft JW
• Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility.
  PloS one 2018 Spaulding K, Takaba K, Collins A, Faraji F, Wang G, Aguayo E, Ge L, Saloner D, Wallace AW, Baker AJ, Lovett DH, Ratcliffe MB
• Correction to: Abstracts : 29th European Congress of Pathology.
  Virchows Archiv : an international journal of pathology 2018 Al-Masri H, Ratcliffe M, Sharpe A, Barker C, Scorer P, Scott M, Rebelatto M, Walker J
• Ischemic Mitral Regurgitation: Abnormal Strain Overestimates Nonviable Myocardium.
  The Annals of thoracic surgery 2018 Morgan AE, Zhang Y, Tartibi M, Goldburg S, Kim JJ, Nguyen TD, Guccione J, Ge L, Weinsaft JW, Ratcliffe MB
• Multiplanar strain quantification for assessment of right ventricular dysfunction and non-ischemic fibrosis among patients with ischemic mitral regurgitation.
  PloS one 2017 Di Franco A, Kim J, Rodriguez-Diego S, Khalique O, Siden JY, Goldburg SR, Mehta NK, Srinivasan A, Ratcliffe MB, Levine RA, Crea F, Devereux RB, Weinsaft JW
• Echocardiography-quantified myocardial strain-a marker of global and regional infarct size that stratifies likelihood of left ventricular thrombus.
  Echocardiography (Mount Kisco, N.Y.) 2017 Kim J, Rodriguez-Diego S, Srinivasan A, Brown RM, Pollie MP, Di Franco A, Goldburg SR, Siden JY, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW
• Association of Uneven MitraClip Application and Leaflet Stress in a Finite Element Model.
  JAMA surgery 2017 Morgan AE, Wozniak CJ, Gulati S, Ge L, Grossi EA, Weinsaft JW, Ratcliffe MB
• Right Ventricular Dysfunction Impairs Effort Tolerance Independent of Left Ventricular Function Among Patients Undergoing Exercise Stress Myocardial Perfusion Imaging.
  Circulation. Cardiovascular imaging 2016 Kim J, Di Franco A, Seoane T, Srinivasan A, Kampaktsis PN, Geevarghese A, Goldburg SR, Khan SA, Szulc M, Ratcliffe MB, Levine RA, Morgan AE, Maddula P, Rozenstrauch M, Shah T, Devereux RB, Weinsaft JW
• Undersized Mitral Annuloplasty Increases Strain in the Proximal Lateral Left Ventricular Wall.
  The Annals of thoracic surgery 2016 Pantoja JL, Morgan AE, Grossi EA, Jensen MO, Weinsaft JW, Levine RA, Ge L, Ratcliffe MB
• Neochord placement versus triangular resection in mitral valve repair: A finite element model.
  The Journal of surgical research 2016 Morgan AE, Pantoja JL, Grossi EA, Ge L, Weinsaft JW, Ratcliffe MB
• Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model.
  The Journal of heart valve disease 2016 Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE
• Moderate Ischemic Mitral Regurgitation After Posterolateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone.
  The Annals of thoracic surgery 2016 Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Tartibi M, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB
• Finite Element Modeling of Mitral Valve Repair.
  Journal of biomechanical engineering 2016 Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione JM, Ge L, Ratcliffe M
• Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention.
  Coronary artery disease 2015 Goyal P, Kim J, Feher A, Ma CL, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW
• Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis.
  The Annals of thoracic surgery 2015 Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB
• Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices.
  Annals of cardiothoracic surgery 2015 Yaffee DW, Grossi EA, Ratcliffe MB
• Studies on postinfarct left ventricular remodeling: state of the art.
  The Annals of thoracic surgery 2015 Ratcliffe M, Cambronero N, Takaba K, Ge L
• Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation.
  The Journal of heart valve disease 2014 Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB
• A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium.
  Frontiers in physiology 2014 Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ
• Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone.
  American journal of physiology. Heart and circulatory physiology 2014 Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ
• Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis.
  The Annals of thoracic surgery 2014 Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB
• Patient-specific finite element modeling of the Cardiokinetix Parachute(®) device: effects on left ventricular wall stress and function.
  Medical & biological engineering & computing 2014 Lee LC, Ge L, Zhang Z, Pease M, Nikolic SD, Mishra R, Ratcliffe MB, Guccione JM
• Invited commentary.
  The Annals of thoracic surgery 2014 Ratcliffe M, Cambronero N, Long S
• Applications of computational modeling in cardiac surgery.
  Journal of cardiac surgery 2014 Lee LC, Genet M, Dang AB, Ge L, Guccione JM, Ratcliffe MB
• Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation.
  The Annals of thoracic surgery 2014 Ge L, Morrel WG, Ward A, Mishra R, Zhang Z, Guccione JM, Grossi EA, Ratcliffe MB
• Invited commentary.
  The Annals of thoracic surgery 2014 Ratcliffe MB, Wozniak CJ
• Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function.
  Journal of applied physiology (Bethesda, Md. : 1985) 2013 Lee LC, Wenk JF, Zhong L, Klepach D, Zhang Z, Ge L, Ratcliffe MB, Zohdi TI, Hsu E, Navia JL, Kassab GS, Guccione JM
• Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart.
  The Annals of thoracic surgery 2013 Wenk JF, Ge L, Zhang Z, Mojsejenko D, Potter DD, Tseng EE, Guccione JM, Ratcliffe MB
• Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction.
  The Annals of thoracic surgery 2013 Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB
• Left ventricular pressure gating in ovine cardiac studies: a software-based method.
  Journal of biomechanical engineering 2013 Acevedo-Bolton G, Suzuki T, Malhotra D, Zhang Z, Wallace AW, Guccione JM, Saloner DA, Ratcliffe MB
• Invited commentary.
  The Annals of thoracic surgery 2012 Ratcliffe M, Cambronero N, Ge L
• Finite element modeling of mitral leaflet tissue using a layered shell approximation.
  Medical & biological engineering & computing 2012 Wenk JF, Ratcliffe MB, Guccione JM
• Material properties of CorCap passive cardiac support device.
  The Annals of thoracic surgery 2012 Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE
• Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stress.
  The Annals of thoracic surgery 2012 Carrick R, Ge L, Lee LC, Zhang Z, Mishra R, Axel L, Guccione JM, Grossi EA, Ratcliffe MB
• The benefit of enhanced contractility in the infarct borderzone: a virtual experiment.
  Frontiers in physiology 2012 Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB
• Growth and remodeling of the left ventricle: A case study of myocardial infarction and surgical ventricular restoration.
  Mechanics research communications 2012 Klepach D, Lee LC, Wenk JF, Ratcliffe MB, Zohdi TI, Navia JA, Kassab GS, Kuhl E, Guccione JM
• A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure.
  Computer methods in biomechanics and biomedical engineering 2012 Wenk JF, Ge L, Zhang Z, Soleimani M, Potter DD, Wallace AW, Tseng E, Ratcliffe MB, Guccione JM
• The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation.
  The Annals of thoracic surgery 2012 Wong VM, Wenk JF, Zhang Z, Cheng G, Acevedo-Bolton G, Burger M, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB, Ge L
• Electromechanical feedback with reduced cellular connectivity alters electrical activity in an infarct injured left ventricle: a finite element model study.
  American journal of physiology. Heart and circulatory physiology 2011 Wall ST, Guccione JM, Ratcliffe MB, Sundnes JS
• Invited commentary.
  The Annals of thoracic surgery 2011 Wenk J, Guccione J, Ratcliffe M
• Moderate mitral regurgitation accelerates left ventricular remodeling after posterolateral myocardial infarction.
  The Annals of thoracic surgery 2011 Soleimani M, Khazalpour M, Cheng G, Zhang Z, Acevedo-Bolton G, Saloner DA, Mishra R, Wallace AW, Guccione JM, Ge L, Ratcliffe MB
• A novel method for quantifying in-vivo regional left ventricular myocardial contractility in the border zone of a myocardial infarction.
  Journal of biomechanical engineering 2011 Lee LC, Wenk JF, Klepach D, Zhang Z, Saloner D, Wallace AW, Ge L, Ratcliffe MB, Guccione JM
• A novel method for quantifying the in-vivo mechanical effect of material injected into a myocardial infarction.
  The Annals of thoracic surgery 2011 Wenk JF, Eslami P, Zhang Z, Xu C, Kuhl E, Gorman JH, Robb JD, Ratcliffe MB, Gorman RC, Guccione JM
• Operative risks and survival in veterans with severe aortic stenosis: surgery versus medical therapy.
  The Annals of thoracic surgery 2011 Chitsaz S, Jaussaud N, Chau E, Yan KS, Azadani AN, Ratcliffe MB, Tseng EE
• Invited commentary.
  The Annals of thoracic surgery 2011 Mishra RK, Ratcliffe M
• Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction.
  Journal of biomechanical engineering 2011 Wenk JF, Sun K, Zhang Z, Soleimani M, Ge L, Saloner D, Wallace AW, Ratcliffe MB, Guccione JM
• Comparison of the Young-Laplace law and finite element based calculation of ventricular wall stress: implications for postinfarct and surgical ventricular remodeling.
  The Annals of thoracic surgery 2011 Zhang Z, Tendulkar A, Sun K, Saloner DA, Wallace AW, Ge L, Guccione JM, Ratcliffe MB
• First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitation.
  The Annals of thoracic surgery 2010 Wenk JF, Zhang Z, Cheng G, Malhotra D, Acevedo-Bolton G, Burger M, Suzuki T, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB
• Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone.
  The Journal of thoracic and cardiovascular surgery 2010 Sun K, Zhang Z, Suzuki T, Wenk JF, Stander N, Einstein DR, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB
• Fluid-Structure Interactions of the Mitral Valve and Left Heart: Comprehensive Strategies, Past, Present and Future.
  International journal for numerical methods in engineering 2010 Einstein DR, Del Pin F, Jiao X, Kuprat AP, Carson JP, Kunzelman KS, Cochran RP, Guccione JM, Ratcliffe MB
• Severe aortic stenosis in a veteran population: treatment considerations and survival.
  The Annals of thoracic surgery 2010 Bakaeen FG, Chu D, Ratcliffe M, Gopaldas RR, Blaustein AS, Venkat R, Huh J, LeMaire SA, Coselli JS, Carabello BA
• Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study.
  The Annals of thoracic surgery 2010 Jhun CS, Wenk JF, Zhang Z, Wall ST, Sun K, Sabbah HN, Ratcliffe MB, Guccione JM
• A method for automatically optimizing medical devices for treating heart failure: designing polymeric injection patterns.
  Journal of biomechanical engineering 2009 Wenk JF, Wall ST, Peterson RC, Helgerson SL, Sabbah HN, Burger M, Stander N, Ratcliffe MB, Guccione JM
• A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm.
  Journal of biomechanical engineering 2009 Sun K, Stander N, Jhun CS, Zhang Z, Suzuki T, Wang GY, Saeed M, Wallace AW, Tseng EE, Baker AJ, Saloner D, Einstein DR, Ratcliffe MB, Guccione JM
• Adaptive generation of multimaterial grids from imaging data for biomedical Lagrangian fluid-structure simulations.
  Biomechanics and modeling in mechanobiology 2009 Carson JP, Kuprat AP, Jiao X, Dyedov V, Del Pin F, Guccione JM, Ratcliffe MB, Einstein DR
• The use of computational flow modeling (CFD) to determine the effect of left ventricular shape on blood flow in the left ventricle.
  The Annals of thoracic surgery 2009 Ge L, Ratcliffe M
• The biomechanics of arterial elastin.
  Journal of the mechanical behavior of biomedical materials 2008 Gundiah N, Ratcliffe MB, Pruitt LA
• A simple correction for anomalous coronary arteries in adults.
  The Journal of thoracic and cardiovascular surgery 2008 Guy TS, Tseng E, Ratcliffe MB, Azakie A, Karl TR
• National Institutes of Health funding for cardiothoracic surgical research.
  The Journal of thoracic and cardiovascular surgery 2008 Ratcliffe MB, Howard C, Mann M, del Nido P
• Asymmetric mechanical properties of porcine aortic sinuses.
  The Annals of thoracic surgery 2008 Gundiah N, Kam K, Matthews PB, Guccione J, Dwyer HA, Saloner D, Chuter TA, Guy TS, Ratcliffe MB, Tseng EE
• Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysm.
  The Journal of thoracic and cardiovascular surgery 2008 Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Hsu EW, Saloner DA, Guccione JM
• National institutes of health funding for surgical research.
  Annals of surgery 2008 Mann M, Tendulkar A, Birger N, Howard C, Ratcliffe MB
• Cost-utility analysis of treatment with olanzapine compared with other antipsychotic treatments in patients with schizophrenia in the pan-European SOHO study.
  PharmacoEconomics 2008 Knapp M, Windmeijer F, Brown J, Kontodimas S, Tzivelekis S, Haro JM, Ratcliffe M, Hong J, Novick D, SOHO Study Group
• Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep.
  The Journal of thoracic and cardiovascular surgery 2007 Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB
• The effect of preoperative diastolic dysfunction on outcome after surgical ventricular remodeling.
  The Journal of thoracic and cardiovascular surgery 2007 Ratcliffe MB, Guy TS
• Invited commentary.
  The Annals of thoracic surgery 2007 Ratcliffe MB
• Transmural heterogeneity of diffusion anisotropy in the sheep myocardium characterized by MR diffusion tensor imaging.
  American journal of physiology. Heart and circulatory physiology 2007 Jiang Y, Guccione JM, Ratcliffe MB, Hsu EW
• Remission and relapse in the outpatient care of schizophrenia: three-year results from the Schizophrenia Outpatient Health Outcomes study.
  Journal of clinical psychopharmacology 2006 Haro JM, Novick D, Suarez D, Alonso J, Lépine JP, Ratcliffe M, SOHO Study Group
• Theoretical impact of the injection of material into the myocardium: a finite element model simulation.
  Circulation 2006 Wall ST, Walker JC, Healy KE, Ratcliffe MB, Guccione JM
• The treatment of ischemic heart failure with surgical ventricular restoration (SVR): new evidence of benefit.
  Journal of cardiac failure 2006 Ratcliffe MB
• The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: a magnetic resonance imaging tagging study.
  The Journal of thoracic and cardiovascular surgery 2006 Guccione JM, Walker JC, Beitler JR, Moonly SM, Zhang P, Guttman MA, Ozturk C, McVeigh ER, Wallace AW, Saloner DA, Ratcliffe MB
• Left ventricular volume and function after endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm in sheep.
  The Journal of thoracic and cardiovascular surgery 2005 Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Saloner DA, Wallace AW, Ratcliffe MB
• MRI-based finite-element analysis of left ventricular aneurysm.
  American journal of physiology. Heart and circulatory physiology 2005 Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Fata B, Hsu EW, Saloner D, Guccione JM
• Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep.
  The Journal of thoracic and cardiovascular surgery 2005 Walker JC, Guccione JM, Jiang Y, Zhang P, Wallace AW, Hsu EW, Ratcliffe MB
• Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C
• Effect of ventricular size and patch stiffness in surgical anterior ventricular restoration: a finite element model study.
  The Annals of thoracic surgery 2005 Dang AB, Guccione JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB
• Akinetic myocardial infarcts must contain contracting myocytes: finite-element model study.
  American journal of physiology. Heart and circulatory physiology 2004 Dang AB, Guccione JM, Mishell JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB
• Myosplint decreases wall stress without depressing function in the failing heart: a finite element model study.
  The Annals of thoracic surgery 2003 Guccione JM, Salahieh A, Moonly SM, Kortsmit J, Wallace AW, Ratcliffe MB
• Effect of preoperative delay on prognosis for patients with early stage non-small cell lung cancer.
  The Journal of thoracic and cardiovascular surgery 2003 Quarterman RL, McMillan A, Ratcliffe MB, Block MI
• A finite element model of left ventricular cellular transplantation in dilated cardiomyopathy.
  ASAIO journal (American Society for Artificial Internal Organs : 1992) 2002 Quarterman RL, Moonly S, Wallace AW, Guccione J, Ratcliffe MB
• Ventricular remodeling surgery for heart failure: small animals and how to measure an improvement in ventricular function.
  The Annals of thoracic surgery 2002 Teerlink JR, Ratcliffe MB
• Left ventricular volume reduction by radiofrequency heating of chronic myocardial infarction in patients with congestive heart failure.
  Circulation 2002 Victal OA, Teerlink JR, Gaxiola E, Wallace AW, Najar S, Camacho DH, Gutierrez A, Herrera G, Zuniga G, Mercado-Rios F, Ratcliffe MB
• Residual stress produced by ventricular volume reduction surgery has little effect on ventricular function and mechanics: a finite element model study.
  The Journal of thoracic and cardiovascular surgery 2001 Guccione JM, Moonly SM, Wallace AW, Ratcliffe MB
• Cardiopulmonary Complications Following Cardiac Surgery.
  Current treatment options in cardiovascular medicine 2001 Quarterman RL, Wallace A, Ratcliffe MB
• Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study.
  The Annals of thoracic surgery 2001 Guccione JM, Moonly SM, Moustakidis P, Costa KD, Moulton MJ, Ratcliffe MB, Pasque MK
• Batista's operation: what have we learned?
  Journal of the American College of Cardiology 2000 Ratcliffe M
• Effect of induction and reperfusion with warm substrate-enriched cardioplegia on ventricular function.
  The Annals of thoracic surgery 2000 Wallace AW, Ratcliffe MB, Nosé PS, Bellows W, Moores W, McEnany MT, Flachsbart K, Mangano DT
• Collection of process data after cardiac surgery: initial implementation with a Java-based intranet applet.
  The Annals of thoracic surgery 2000 Ratcliffe MB, Khan JH, Magee KM, McElhinney DB, Hubner C
• Radio frequency heating of chronic ovine infarct leads to sustained infarct area and ventricular volume reduction.
  The Journal of thoracic and cardiovascular surgery 2000 Ratcliffe MB, Wallace AW, Teerlink JR, Hong J, Salahieh A, Sung SH, Keung EC, Lee RJ
• The effect of diastolic stiffness on ventricular function after partial ventriculectomy: a finite element simulation.
  ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000 Ratcliffe MB, Hong J, Salahieh A, Wallace AW
• Ventricular volume, chamber stiffness, and function after anteroapical aneurysm plication in the sheep.
  The Journal of thoracic and cardiovascular surgery 2000 Ratcliffe MB, Wallace AW, Salahieh A, Hong J, Ruch S, Hall TS
• L-arginine infusion dilates coronary vasculature in patients undergoing coronary bypass surgery.
  Anesthesiology 1999 Wallace AW, Ratcliffe MB, Galindez D, Kong JS
• The effect of ventricular volume reduction surgery in the dilated, poorly contractile left ventricle: a simple finite element analysis.
  The Journal of thoracic and cardiovascular surgery 1998 Ratcliffe MB, Hong J, Salahieh A, Ruch S, Wallace AW
• Dynamic three-dimensional imaging of the mitral valve and left ventricle by rapid sonomicrometry array localization.
  The Journal of thoracic and cardiovascular surgery 1996 Gorman JH, Gupta KB, Streicher JT, Gorman RC, Jackson BM, Ratcliffe MB, Bogen DK, Edmunds LH
• Use of sonomicrometry and multidimensional scaling to determine the three-dimensional coordinates of multiple cardiac locations: feasibility and initial implementation.
  IEEE transactions on bio-medical engineering 1995 Ratcliffe MB, Gupta KB, Streicher JT, Savage EB, Bogen DK, Edmunds LH
• Pathogenesis of acute ischemic mitral regurgitation in three dimensions.
  The Journal of thoracic and cardiovascular surgery 1995 Gorman RC, McCaughan JS, Ratcliffe MB, Gupta KB, Streicher JT, Ferrari VA, St John-Sutton MG, Bogen DK, Edmunds LH
• A novel sialyl LewisX analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion.
  Circulation 1994 Lefer DJ, Flynn DM, Phillips ML, Ratcliffe M, Buda AJ
• Changes in passive mechanical stiffness of myocardial tissue with aneurysm formation.
  Circulation 1994 Gupta KB, Ratcliffe MB, Fallert MA, Edmunds LH, Bogen DK
• Left ventricular assist without thoracotomy: clinical experience with the Dennis method.
  The Annals of thoracic surgery 1994 Edmunds LH, Herrmann HC, DiSesa VJ, Ratcliffe MB, Bavaria JE, McCarthy DM
• Large animal model of ischemic mitral regurgitation.
  The Annals of thoracic surgery 1994 Llaneras MR, Nance ML, Streicher JT, Lima JA, Savino JS, Bogen DK, Deac RF, Ratcliffe MB, Edmunds LH
• Repair of left ventricular aneurysm. Changes in ventricular mechanics, hemodynamics, and oxygen consumption.
  The Journal of thoracic and cardiovascular surgery 1992 Savage EB, Downing SW, Ratcliffe MB, Fallert M, Gupta KB, Tyson GS, Bogen DK, Edmunds LH
• Left ventricular mechanics of ejecting, postischemic hearts during left ventricular circulatory assistance.
  The Journal of thoracic and cardiovascular surgery 1991 Ratcliffe MB, Bavaria JE, Wenger RK, Bogen DK, Edmunds LH
• Myocardial oxygen utilization after reversible global ischemia.
  The Journal of thoracic and cardiovascular surgery 1990 Bavaria JE, Furukawa S, Kreiner G, Ratcliffe MB, Streicher J, Bogen DK, Edmunds LH
• Large animal model of left ventricular aneurysm.
  The Annals of thoracic surgery 1989 Markovitz LJ, Savage EB, Ratcliffe MB, Bavaria JE, Kreiner G, Iozzo RV, Hargrove WC, Bogen DK, Edmunds LH
• Measurement of end-systolic pressure-volume relations by intra-aortic balloon occlusion.
  Circulation 1989 Gupta KB, Bavaria JE, Ratcliffe MB, Edmunds LH, Bogen DK
• Surgery for left ventricular aneurysm. Early survival with and without endocardial resection.
  Circulation 1989 Stephenson LW, Hargrove WC, Ratcliffe MB, Edmunds LH
• Flow dynamics of peripheral venous catheters during extracorporeal membrane oxygenation with a centrifugal pump.
  The Journal of thoracic and cardiovascular surgery 1988 Wenger RK, Bavaria JE, Ratcliffe MB, Bogen D, Edmunds LH
• Changes in left ventricular systolic wall stress during biventricular circulatory assistance.
  The Annals of thoracic surgery 1988 Bavaria JE, Ratcliffe MB, Gupta KB, Wenger RK, Bogen DK, Edmunds LH