Mark Pownall, PhD
Assistant Researcher
Biochemistry and Biophysics
School of Medicine

Education & Training

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• PhD Genetics Yale University 12/2023

Interests

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• embryonic development
• transcription
• chromatin
• super-resolution microscopy

Websites

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• Pownall Lab (pownall-lab.org)

Publications (8)

Top publication keywords:
MicroscopyChromatinEmbryo, NonmammalianMicroscopy, FluorescenceEmbryonic DevelopmentCiliaTeratogensZygoteTranscription, GeneticToxicity TestsXenopus laevisNanog Homeobox ProteinHistocytochemistryCell NucleusNucleosomes

• Synaptic activity controls local exposure of an 'eat-me' signal via ANO3-ITPR1 signaling.
  bioRxiv : the preprint server for biology 2026 Shroff K, O'Brien MC, Smith TJ, Fang J, Yu KS, Lombroso SI, Feng S, Chen C, Mohl GA, Rose IVL, Lokesh NR, Pownall ME, Jan LY, Kampmann M
• In situ proteomics unveils specialized domains for extrasynaptic signaling on neuronal cilia.
  Science advances 2026 Chang CH, Trinh VN, Novak SW, Lokesh NR, Montecinos CK, Boassa D, Pownall ME, Kalocsay M, Nachury MV
• Microscopy methods for the in vivo study of nanoscale nuclear organization.
  Biochemical Society transactions 2025 Lokesh NR, Pownall ME
• Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin.
  Science (New York, N.Y.) 2023 Pownall ME, Miao L, Vejnar CE, M'Saad O, Sherrard A, Frederick MA, Benitez MDJ, Boswell CW, Zaret KS, Bewersdorf J, Giraldez AJ
• The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation.
  Molecular cell 2022 Miao L, Tang Y, Bonneau AR, Chan SH, Kojima ML, Pownall ME, Vejnar CE, Gao F, Krishnaswamy S, Hendry CE, Giraldez AJ
• Xenopus embryos show a compensatory response following perturbation of the Notch signaling pathway.
  Developmental biology 2019 Solini GE, Pownall ME, Hillenbrand MJ, Tocheny CE, Paudel S, Halleran AD, Bianchi CH, Huyck RW, Saha MS
• Transcriptome of Xenopus andrei, an octoploid frog, during embryonic development.
  Data in brief 2018 Pownall ME, Cutler RR, Saha MS
• Histological Observation of Teratogenic Phenotypes Induced in Frog Embryo Assays.
  Methods in molecular biology (Clifton, N.J.) 2018 Pownall ME, Saha MS