Marissa Raymond-Flesch, MD, MPH
Professor
Pediatrics
School of Medicine

Dr. Raymond-Flesch is a Professor in the Philip R. Lee Institute for Health Policy Studies (IHPS) and the Division of Adolescent and Young Adult Medicine within the Department of Pediatrics.

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Clinically, she practices Adolescent Medicine with patients 12 to 26 years old, including treatment of depression, anxiety, and eating disorders; providing all types of contraception; and providing primary care for patients with complex medical and mental health conditions. Her program of research focuses on understanding and improving the mental health, reproductive health, and healthcare access of adolescents and young adults, particularly those from rural and underserved communities. She is especially interested in using community-based participatory research to design meaningful research projects and create health inventions that communities want and need. She has three main branches of research.

1. Novel therapeutics for patients with eating disorders: Dr. Raymond-Flesch is the Principal Investigator for the Study of Psilocybin for Anorexia Nervosa in Young Adults (SPANYA). Psilocybin has shown remarkable potential for the treatment of other severe and enduring mental illnesses, and its safety profile has been remarkably good across studies. Psilocybin’s mechanisms of action are through serotonergic and anatomical pathways that are implicated in anorexia, making it a promising approach. SPANYA is testing the efficacy of psilocybin therapy in patients with ongoing brain development, ages 18 to 25 years old.

2. Improving adolescent and young adult access to abortion services: Dr. Raymond-Flesch and her team have developed, tested, and disseminated a curriculum to train pediatricians in the provision of medication abortion in primary care settings. She is also the senior investigator on a national mixed-methods study to better understand the post-Dobbs era abortion referral practices of providers who serve adolescents and young adults across the country. The goal of this project is to better characterize the systems-level barriers to abortion referral and better understand the strategies that providers are using to promote access to comprehensive health care.

3. Investigating the mental health, reproductive health, and wellbeing outcomes for Latine youth in immigrant communities: In partnership with colleagues from RTI, UC Berkeley, and the Monterey County Health Department, Dr. Raymond-Flesch is examining the relationship between gang violence, unintended teen pregnancies, and mental health in a cohort of 599 early adolescents in Salinas, California - a small, predominantly Latino community in California’s rural central coast. To date, this work has highlighted the critical role that family plays in positive youth development, reducing depressive symptoms, buffering traumatic experiences, and increasing reproductive health knowledge. The second phase of this project, "A Crecer: Young Adult Health Study," is following the same participants into young adulthood to further assess the factors that support rural youth to thrive.

Awards

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  • Hilary E.C. Millar Award for Innovative Approaches to Adolescent Health Care, Society of Adolescent Health and Medicine, 2025
  • Distinction in Mentoring Award, Academic Senate, University of California San Francisco, 2025
  • Faculty Leadership Award, Department of Pediatrics Fellows Leadership & Advocacy Group, University of California San Francisco, 2020
  • Haile T. Debas Academy of Medical Educators Excellence in Teaching Award, University of California San Francisco, 2020
  • John A. Watson Faculty Scholar, University of California San Francisco, 2017
  • Melvin M. Grumbach Award for Excellence in Research, University of California San Francisco, 2016
  • NIH Loan Repayment Program, National Institute of Minority Health and Health Disparities, 2015-2017
  • David Knopf Award for Service, University of California San Francisco, 2014
  • Honors in Public Service, Cornell University School of Medicine, 2008
  • Community Service Award, Medical Society of New York, 2008
  • Macy’s Fellowship in Public Health, Columbia University, 2006

Education & Training

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  • Diversity, Equity, and Inclusion Champion Training University of California 2018
  • Fellow Adolescent and Young Adult Medicine University of California San Francisco 2016
  • Fellow Health Policy University of California San Francisco 2016
  • Residency and Chief Residency Internal Medicine and Pediatrics Mount Sinai Hospital 2012
  • M.D. Medicine Cornell University 2008
  • M.P.H. Public Health, Adolescent Health Columbia University, Mailman School of Public Health 2007
  • B.S. Brain and Cognitive Science Massachusetts Institute of Technology 2003

Interests

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  • Eating Disorders
  • Reproductive Health
  • Adolescent Health
  • Public Health Policy
  • Health of Underserved Communities
  • Depression and Mental Health

Grants and Projects

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Publications (50)

Top publication keywords:
Public HealthHealth Services Needs and DemandEmigrants and ImmigrantsConsciousnessAbortion, LegalHealth Services AccessibilityAdolescent MedicinePsilocybinSocial CapitalSocial StigmaCultural DiversityAdolescent Health ServicesHealth PromotionRacismAbortion, Induced

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