Marina Radoul, PhD
Specialist
Physical Therapy
School of Medicine

Education & Training

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• PhD Chemical Physics Weizmann Institute of Science 10/2010

Publications (29)

Top publication keywords:
CytochromesFerric CompoundsDacarbazineNitric OxideElectron Spin Resonance SpectroscopyHistone Deacetylase InhibitorsFerrosoferric OxideGlioblastomaHemePseudomonas aeruginosaNitrite ReductasesCarbon-13 Magnetic Resonance SpectroscopyApoferritinsIsocitrate DehydrogenaseBrain Neoplasms

• Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
  Neuro-oncology 2022 Minami N, Hong D, Stevers N, Barger CJ, Radoul M, Hong C, Chen L, Kim Y, Batsios G, Gillespie AM, Pieper RO, Costello JF, Viswanath P, Ronen SM
• Preclinical Development of NRTX-1001, an Inhibitory Interneuron Cellular Therapeutic for the Treatment of Chronic Focal Epilepsy (S13.007).
  Neurology 2022 Mansi Parekh, Philip Hampel, Marina Radoul, Eric Steven Sevilla, David Traver, Hannah Kim, Nathalie Picard, Andrew Adler, Luis Fuentealba, Jiayin Li, Adrian Bates, Daniel Cherkowsky, Marina Bershteyn,…
• Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.
  Metabolites 2021 Radoul M, Hong D, Gillespie AM, Najac C, Viswanath P, Pieper RO, Costello JF, Luchman HA, Ronen SM
• BIOM-19. METABOLIC ALTERATION INDUCED BY SELECTIVE KNOCK DOWN OF GABPB1L IN U251 CELLS.
  Neuro-Oncology 2020 Noriaki Minami, Vinay Ayyappan, Nick Stevers, Abigail Molloy, Georgios Batsios, Donghyun Hong, Anne Marie Gillespie, Elavarasan Subramani, Marina Radoul, Joseph Costello, Pavithra Viswanath, Sabrina …
• Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment.
  Cancer research 2020 Subramani E, Radoul M, Najac C, Batsios G, Molloy AR, Hong D, Gillespie AM, Santos RD, Viswanath P, Costello JF, Pieper RO, Ronen SM

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• MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
  Theranostics 2020 Molloy AR, Najac C, Viswanath P, Lakhani A, Subramani E, Batsios G, Radoul M, Gillespie AM, Pieper RO, Ronen SM
• EXTH-20. HYPERPOLARIZED [2-13C] PYRUVATE TO [5-13C] GLUTAMATE AS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY.
  Neuro-Oncology 2019 Elavarasan Subramani, Chloe Najac, Georgios Batsios, Pavithra Viswanath, Marina Radoul, Anne Marie Gillespie, Russell O Pieper, Sabrina Ronen
• Abstract 5263: 1H and 13C MRS-based metabolic markers of IDH1 mutant glioma response to temozolomide therapy.
  Cancer Research 2019 Elavarasan Subramani, Chloe Najac, Georgios Batsios, Pavithra Viswanath, Marina Radoul, Anne Marie Gillespie, Russell O. Pieper, Sabrina M. Ronen
• In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.
  Scientific reports 2019 Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM
• HDAC inhibition in glioblastoma monitored by hyperpolarized 13 C MRSI.
  NMR in biomedicine 2018 Radoul M, Najac C, Viswanath P, Mukherjee J, Kelly M, Gillespie AM, Chaumeil MM, Eriksson P, Delos Santos R, Pieper RO, Ronen SM
• EXTH-76. 1H AND HYPERPOLARIZED 13C MRS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY.
  Neuro-Oncology 2018 Elavarasan Subramani, Chloe Najac, Georgios Batsios, Pavithra Viswanath, Marina Radoul, Anne Marie Gillespie, Russell Pieper, Sabrina Ronen
• Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.
  Cancer & metabolism 2018 Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM
• 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas.
  Cancer research 2018 Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM
• METB-14. DOWN-REGULATION OF ACETATE METABOLISM TOWARDS FATTY ACIDS IN IDH1 MUTANT GLIOMA.
  Neuro-Oncology 2017 Chloe Najac, Marina Radoul, Pavithra Viswanath, Myriam M Chaumeil, Sabrina Ronen
• TMOD-20. EARLY DETECTION OF HDAC INHIBITION IN GLIOBLASTOMA USING ADVANCED HYPERPOLARIZED 13C MRSI.
  Neuro-Oncology 2017 Marina Radoul, Myriam M Chaumeil, Pia Eriksson, Chloe Najac, Pavithra Viswanath, Anne Marie Gillespie, Joydeep Mukherjee, Russell Pieper, Sabrina Ronen
• Correction to Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.
  Inorganic chemistry 2017 Cohen MR, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D
• Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.
  Inorganic chemistry 2017 Ramirez Cohen M, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D
• Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.
  NeuroImage. Clinical 2016 Chaumeil MM, Radoul M, Najac C, Eriksson P, Viswanath P, Blough MD, Chesnelong C, Luchman HA, Cairncross JG, Ronen SM
• Genetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex.
  Scientific reports 2016 Radoul M, Lewin L, Cohen B, Oren R, Popov S, Davidov G, Vandsburger MH, Harmelin A, Bitton R, Greneche JM, Neeman M, Zarivach R
• MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.
  Molecular cancer therapeutics 2016 Radoul M, Chaumeil MM, Eriksson P, Wang AS, Phillips JJ, Ronen SM
• CBIO-42DOWN REGULATION OF PYRUVATE DEHYDROGENASE ACTIVITY IS ESSENTIAL FOR CELL PROLIFERATION IN IDH1 MUTANT GLIOMA CELLS.
  Neuro-Oncology 2015 Pavithra Viswanath, Jose L. Izquierdo-Garcia, Pia Eriksson, Larry Cai, Marina Radoul, Myriam M. Chaumeil, Michael Blough, H. Artee Luchmann, Samuel Weiss, J. Gregory Cairncross, Joanna J. Phillips, …
• IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
  Cancer research 2015 Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM
• Ovarian carcinoma: quantitative biexponential MR imaging relaxometry reveals the dynamic recruitment of ferritin-expressing fibroblasts to the angiogenic rim of tumors.
  Radiology 2013 Vandsburger MH, Radoul M, Addadi Y, Mpofu S, Cohen B, Eilam R, Neeman M
• MRI reporter genes: applications for imaging of cell survival, proliferation, migration and differentiation.
  NMR in biomedicine 2012 Vandsburger MH, Radoul M, Cohen B, Neeman M
• Solvent accessibility in the distal heme pocket of the nitrosyl d(1)-heme complex of Pseudomonas stutzeri cd(1) nitrite reductase.
  Biochemistry 2012 Radoul M, Barak Y, Rinaldo S, Cutruzzolà F, Pecht I, Goldfarb D
• Dynamic hydrogen-bonding network in the distal pocket of the nitrosyl complex of Pseudomonas aeruginosa cd1 nitrite reductase.
  Journal of the American Chemical Society 2011 Radoul M, Bykov D, Rinaldo S, Cutruzzolà F, Neese F, Goldfarb D
• Revisiting the nitrosyl complex of myoglobin by high-field pulse EPR spectroscopy and quantum mechanical calculations.
  Physical chemistry chemical physics : PCCP 2010 Radoul M, Sundararajan M, Potapov A, Riplinger C, Neese F, Goldfarb D
• Heme d1 nitrosyl complex of cd1 nitrite reductase studied by high-field-pulse electron paramagnetic resonance spectroscopy.
  Inorganic chemistry 2009 Radoul M, Centola F, Rinaldo S, Cutruzzolà F, Pecht I, Goldfarb D
• HYSCORE and DEER with an upgraded 95GHz pulse EPR spectrometer.
  Journal of magnetic resonance (San Diego, Calif. : 1997) 2008 Goldfarb D, Lipkin Y, Potapov A, Gorodetsky Y, Epel B, Raitsimring AM, Radoul M, Kaminker I