Marc Shuman, MD
Professor
Medicine
School of Medicine

Awards

Show all (2) Hide

• Honorary Chair Advisory Committee PUMCH Translational Medicine Center,, Peking Union Medical College Hospital, 2013
• Phi Eta Sigma Freshman Honor Society(1 of 25 students and only one elected after one semester), Univ. of Wisconsin-Madison, 1959-1960

Grants and Projects

Show all (12) Hide

• Cancer Center Support Grant, NIH, 1999-2023
• Basic Research in Hematology and Oncology, NIH, 1984-2014
• SPORE in Breast Cancer, NIH, 1992-2013
• Ucsf Prostate Cancer Spore, NIH, 2000-2010
• Proteases in Cancer Biology and Drug Development, NIH, 1997-2010
• Transfusion Biology and Medicine, NIH, 1996-2006
• Urokinase Receptor in Prostate Development and Cancer, NIH, 1993-1997
• Blood Banking Sciences and Related Programs, NIH, 1975-1996
• Biosynthesis and Genetics of Glycoproteins Iib and Iiia, NIH, 1984-1993
• Cellular Regulation of Blood Clotting, NIH, 1981-1992
• Proteinase-inhibitor Reactions in Corneal Endothelium, NIH, 1983-1989
• Mechanism of Activation of Coagulation and Platelets, NIH, 1980-1985

Publications (106)

Top publication keywords:
Urokinase-Type Plasminogen ActivatorLymphokinesFibrinogenThrombopoietinPlatelet Membrane GlycoproteinsLymphoma, Non-HodgkinBlood PlateletsFactor XIIICentral Nervous System NeoplasmsMegakaryocytesThrombinReceptors, Cell SurfaceEndothelial Growth FactorsPlasminogen ActivatorsLymphoma

• Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer.
  JCI insight 2018 Su Y, Liu Y, Behrens CR, Bidlingmaier S, Lee NK, Aggarwal R, Sherbenou DW, Burlingame AL, Hann BC, Simko JP, Premasekharan G, Paris PL, Shuman MA, Seo Y, Small EJ, Liu B
• Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.
  The Journal of clinical investigation 2016 Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B
• EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.
  Nature neuroscience 2015 Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, …
• WITHDRAWN: Enhanced Detection and Phenotypic and Karyotypic in Situ Characterization of Circulating Tumor Cells.
  The American journal of pathology 2014 Ge F, Wang DD, Li L, Lin PP, Shuman MA
• Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Kadoch C, Li J, Wong VS, Chen L, Cha S, Munster P, Lowell CA, Shuman MA, Rubenstein JL

Show all (101 more) Hide

• Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.
  Blood 2012 Rubenstein JL, Li J, Chen L, Advani R, Drappatz J, Gerstner E, Batchelor T, Krouwer H, Hwang J, Auerback G, Kadoch C, Lowell C, Munster P, Cha S, Shuman MA, Damon LE
• Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.
  Genes & development 2012 Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan YN, Jan LY
• Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Wieduwilt MJ, Valles F, Issa S, Behler CM, Hwang J, McDermott M, Treseler P, O'Brien J, Shuman MA, Cha S, Damon LE, Rubenstein JL
• Upregulation of Cyclin B1 by miRNA and its implications in cancer.
  Nucleic acids research 2011 Huang V, Place RF, Portnoy V, Wang J, Qi Z, Jia Z, Yu A, Shuman M, Yu J, Li LC
• Time-resolved single-step protease activity quantification using nanoplasmonic resonator sensors.
  ACS nano 2010 Sun C, Su KH, Valentine J, Rosa-Bauza YT, Ellman JA, Elboudwarej O, Mukherjee B, Craik CS, Shuman MA, Chen FF, Zhang X
• The unfolded protein response during prostate cancer development.
  Cancer metastasis reviews 2009 So AY, de la Fuente E, Walter P, Shuman M, Bernales S
• Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Kadoch C, Dinca EB, Voicu R, Chen L, Nguyen D, Parikh S, Karrim J, Shuman MA, Lowell CA, Treseler PA, James CD, Rubenstein JL
• Differential gene expression in central nervous system lymphoma.
  Blood 2009 Rubenstein JL, Shen A, Batchelor TT, Kadoch C, Treseler P, Shuman MA
• Protein biomarker identification in the CSF of patients with CNS lymphoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL
• Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Rubenstein JL, Fridlyand J, Abrey L, Shen A, Karch J, Wang E, Issa S, Damon L, Prados M, McDermott M, O'Brien J, Haqq C, Shuman M
• The epidemiology of prostate cancer--with a focus on nonsteroidal anti-inflammatory drugs.
  Hematology/oncology clinics of North America 2006 Chan JM, Feraco A, Shuman M, Hernández-Díaz S
• Gene expression and angiotropism in primary CNS lymphoma.
  Blood 2006 Rubenstein JL, Fridlyand J, Shen A, Aldape K, Ginzinger D, Batchelor T, Treseler P, Berger M, McDermott M, Prados M, Karch J, Okada C, Hyun W, Parikh S, Haqq C, Shuman M
• Symposium on androgen action in prostate cancer.
  Cancer research 2004 Tindall D, Horne FM, Hruszkewycz A, Mohla S, Shuman M, Wang Z, Kantoff P
• Quinine/quinidine-induced thrombocytopenia: a great imitator.
  Archives of internal medicine 2004 Reddy JC, Shuman MA, Aster RH
• Quantitation of membrane type serine protease 1 (MT-SP1) in transformed and normal cells.
  Biological chemistry 2003 Bhatt AS, Takeuchi T, Ylstra B, Ginzinger D, Albertson D, Shuman MA, Craik CS
• Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model.
  Prostate cancer and prostatic diseases 2003 Bok RA, Hansell EJ, Nguyen TP, Greenberg NM, McKerrow JH, Shuman MA
• Hemorrhage and VEGF expression in a case of primary CNS lymphoma.
  Journal of neuro-oncology 2002 Rubenstein J, Fischbein N, Aldape K, Burton E, Shuman M
• Urokinase plasminogen activator amino-terminal peptides inhibit development of the rat ventral prostate.
  Differentiation; research in biological diversity 2001 Elfman F, Bok R, Conn M, Shuman M, Cunha G
• Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study.
  Cancer research 2001 Bok RA, Halabi S, Fei DT, Rodriquez CR, Hayes DF, Vogelzang NJ, Kantoff P, Shuman MA, Small EJ
• Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption.
  Neoplasia (New York, N.Y.) 2000 Rubenstein JL, Kim J, Ozawa T, Zhang M, Westphal M, Deen DF, Shuman MA
• Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
  Proceedings of the National Academy of Sciences of the United States of America 1999 Takeuchi T, Shuman MA, Craik CS
• Neutralizing anti-vascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a pre-clinical model.
  The Journal of urology 1999 Melnyk O, Zimmerman M, Kim KJ, Shuman M
• Interferon-induced thrombocytopenia: is it time for thrombopoietin.
  Hepatology (Baltimore, Md.) 1998 Martin TG, Shuman MA
• Death-defying yeast identify novel apoptosis genes.
  Cell 1998 Shaham S, Shuman MA, Herskowitz I
• Decreased prostate cancer cell migration by inhibition of the insulin-like growth factor II/Mannose-6-Phosphate receptor.
  Urologic oncology 1997 Evans CP, Elfman F, Cunha G, Shuman MA
• Inhibition of prostate cancer neovascularization and growth by urokinase-plasminogen activator receptor blockade.
  Cancer research 1997 Evans CP, Elfman F, Parangi S, Conn M, Cunha G, Shuman MA
• Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation.
  Annals of internal medicine 1997 Martin TG, Somberg KA, Meng YG, Cohen RL, Heid CA, de Sauvage FJ, Shuman MA
• Circulating thrombopoietin concentrations in thrombocytopenic patients, including cancer patients following chemotherapy, with or without peripheral blood progenitor cell transplantation.
  British journal of haematology 1996 Meng YG, Martin TG, Peterson ML, Shuman MA, Cohen RL, Wong WL
• Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice.
  Cancer research 1996 Min HY, Doyle LV, Vitt CR, Zandonella CL, Stratton-Thomas JR, Shuman MA, Rosenberg S
• Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth.
  Cancer research 1996 Melnyk O, Shuman MA, Kim KJ
• Marked elevation of the serum ferritin is highly specific for disseminated histoplasmosis in AIDS.
  AIDS (London, England) 1995 Kirn DH, Fredericks D, McCutchan JA, Stites D, Shuman M
• Serum ferritin levels correlate with disease activity in patients with AIDS and disseminated histoplasmosis.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995 Kirn DH, Fredericks D, McCutchan JA, Stites D, Shuman M
• Thrombin increases expression of urokinase receptor by activation of the thrombin receptor.
  Investigative ophthalmology & visual science 1995 Yang Z, Cohen RL, Lui GM, Lawrence DA, Shuman MA
• Endocytosis of fibrinogen into hamster megakaryocyte alpha granules is dependent on a dimeric gamma A configuration.
  Blood 1995 Handagama PJ, Amrani DL, Shuman MA
• Immunohistochemical localization of the plasminogen activator inhibitor-1 in breast cancer.
  International journal of cancer 1995 Bianchi E, Cohen RL, Dai A, Thor AT, Shuman MA, Smith HS
• Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells.
  International journal of cancer 1995 Liu G, Shuman MA, Cohen RL
• Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals.
  AIDS (London, England) 1994 Herndier BG, Werner A, Arnstein P, Abbey NW, Demartis F, Cohen RL, Shuman MA, Levy JA
• The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue.
  Cancer research 1994 Bianchi E, Cohen RL, Thor AT, Todd RF, Mizukami IF, Lawrence DA, Ljung BM, Shuman MA, Smith HS
• Endocytosis of fibrinogen into megakaryocyte and platelet alpha-granules is mediated by alpha IIb beta 3 (glycoprotein IIb-IIIa)
  Blood 1993 Handagama P, Scarborough RM, Shuman MA, Bainton DF
• Prevention of metastasis by inhibition of the urokinase receptor.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Crowley CW, Cohen RL, Lucas BK, Liu G, Shuman MA, Levinson AD
• Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules.
  The Journal of clinical investigation 1993 Handagama P, Bainton DF, Jacques Y, Conn MT, Lazarus RA, Shuman MA
• Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells.
  Blood 1991 Cohen RL, Xi XP, Crowley CW, Lucas BK, Levinson AD, Shuman MA
• In vivo defibrination results in markedly decreased amounts of fibrinogen in rat megakaryocytes and platelets.
  The American journal of pathology 1990 Handagama PJ, Shuman MA, Bainton DF
• Human platelets and megakaryocytes contain alternately spliced glycoprotein IIb mRNAs.
  The Journal of biological chemistry 1990 Bray PF, Leung CS, Shuman MA
• Differential effect of platelets on plasminogen activation by tissue plasminogen activator, urokinase, and streptokinase.
  Thrombosis research 1990 Gao SW, Morser J, McLean K, Shuman MA
• A nonradioactive assay for type IV collagen degradation.
  Analytical biochemistry 1990 Wilkinson MJ, Cohen RL, Shuman MA
• Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia.
  Blood 1990 Bray PF, Shuman MA
• The origin of platelet alpha-granule proteins.
  Progress in clinical and biological research 1990 Handagama PJ, Shuman MA, Bainton DF
• Anaphylactoid reactions to vascular graft material presenting with vasodilation and subsequent disseminated intravascular coagulation.
  Anesthesiology 1989 Roizen MF, Rodgers GM, Valone FH, Lampe GH, Benefiel DJ, Gelman S, Rapp J, Weiler JM, Ota M, Shuman MA
• Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules.
  The Journal of clinical investigation 1989 Handagama PJ, Shuman MA, Bainton DF
• Immunogold-surface replica study of ADP-induced ligand binding and fibrinogen receptor clustering in human platelets.
  The American journal of anatomy 1989 Isenberg WM, McEver RP, Phillips DR, Shuman MA, Bainton DF
• Effects of cellular transformation on expression of plasminogen activator inhibitors 1 and 2. Evidence for independent regulation.
  The Journal of biological chemistry 1989 Cohen RL, Niclas J, Lee WM, Wun TC, Crowley CW, Levinson AD, Sadler JE, Shuman MA
• Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Bray PF, Barsh G, Rosa JP, Luo XY, Magenis E, Shuman MA
• Development of antithrombin antibodies following surgery in patients with prosthetic cardiac valves.
  Blood 1988 Stricker RB, Lane PK, Leffert JD, Rodgers GM, Shuman MA, Corash L
• Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17.
  Blood 1988 Rosa JP, Bray PF, Gayet O, Johnston GI, Cook RG, Jackson KW, Shuman MA, McEver RP
• Tissue plasminogen activator in cultured human trabecular meshwork cells. Predominance of enzyme over plasminogen activator inhibitor.
  Investigative ophthalmology & visual science 1988 Shuman MA, Polansky JR, Merkel C, Alvarado JA
• Platelet glycoprotein IIb. Chromosomal localization and tissue expression.
  The Journal of clinical investigation 1987 Bray PF, Rosa JP, Johnston GI, Shiu DT, Cook RG, Lau C, Kan YW, McEver RP, Shuman MA
• Prophylactic heparin in APL.
  Blood 1987 Venook AP, Shuman MA, Corash L
• The transglutaminase in vascular cells and tissues could provide an alternate pathway for fibrin stabilization.
  Blood 1987 Greenberg CS, Achyuthan KE, Borowitz MJ, Shuman MA
• Identification of normal human peripheral blood monocytes and liver as sites of synthesis of coagulation factor XIII a-chain.
  Blood 1987 Weisberg LJ, Shiu DT, Conkling PR, Shuman MA
• The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering.
  The Journal of cell biology 1987 Isenberg WM, McEver RP, Phillips DR, Shuman MA, Bainton DF
• Incorporation of a circulating protein into megakaryocyte and platelet granules.
  Proceedings of the National Academy of Sciences of the United States of America 1987 Handagama PJ, George JN, Shuman MA, McEver RP, Bainton DF
• Localization of the gene for coagulation factor XIII a-chain to chromosome 6 and identification of sites of synthesis.
  The Journal of clinical investigation 1987 Weisberg LJ, Shiu DT, Greenberg CS, Kan YW, Shuman MA
• Enhancement of prothrombin activation on platelets by endothelial cells and mechanism of activation of factor V.
  Thrombosis research 1987 Rodgers GM, Shuman MA
• Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: effects on surface proteins and platelet aggregation.
  Blood 1986 Stricker RB, Wong D, Shiu DT, Reyes PT, Shuman MA
• Congenital thrombotic disorders.
  American journal of hematology 1986 Rodgers GM, Shuman MA
• Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.
  Proceedings of the National Academy of Sciences of the United States of America 1986 Bray PF, Rosa JP, Lingappa VR, Kan YW, McEver RP, Shuman MA
• Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens.
  Blood 1986 Beckstead JH, Stenberg PE, McEver RP, Shuman MA, Bainton DF
• Thrombin-cellular interactions.
  Annals of the New York Academy of Sciences 1986 Shuman MA
• Topographic distribution of a granule membrane protein (GMP-140) that is expressed on the platelet surface after activation: an immunogold-surface replica study.
  Blood cells 1986 Isenberg WM, McEver RP, Shuman MA, Bainton DF
• A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation.
  The Journal of cell biology 1985 Stenberg PE, McEver RP, Shuman MA, Jacques YV, Bainton DF
• Acquired Bernard-Soulier syndrome. Evidence for the role of a 210,000-molecular weight protein in the interaction of platelets with von Willebrand factor.
  The Journal of clinical investigation 1985 Stricker RB, Wong D, Saks SR, Corash L, Shuman MA
• Urokinase binding to bovine corneal endothelial cells.
  Experimental eye research 1985 Shuman MA, Merkel CH
• Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting.
  The Journal of clinical investigation 1985 Greenberg CS, Miraglia CC, Rickles FR, Shuman MA
• Detection and sequence of mutations in the factor VIII gene of haemophiliacs.
  Nature 1985 Gitschier J, Wood WI, Tuddenham EG, Shuman MA, Goralka TM, Chen EY, Lawn RM
• Characterization of the interaction between factor Xa and bovine aortic endothelial cells.
  Biochimica et biophysica acta 1985 Rodgers GM, Shuman MA
• Specific binding of blood coagulation factor XIIIa to thrombin-stimulated platelets.
  The Journal of biological chemistry 1984 Greenberg CS, Shuman MA
• Optimal techniques for the immunocytochemical demonstration of beta-thromboglobulin, platelet factor 4, and fibrinogen in the alpha granules of unstimulated platelets.
  The Histochemical journal 1984 Stenberg PE, Shuman MA, Levine SP, Bainton DF
• Aplastic anemia complicating systemic lupus erythematosus: response to androgens in two patients.
  American journal of hematology 1984 Stricker RB, Shuman MA
• Redistribution of alpha-granules and their contents in thrombin-stimulated platelets.
  The Journal of cell biology 1984 Stenberg PE, Shuman MA, Levine SP, Bainton DF
• The number of receptors for factor VII correlates with the ability of cultured cells to initiate coagulation.
  Blood 1984 Rodgers GM, Broze GJ, Shuman MA
• Prothrombin is activated on vascular endothelial cells by factor Xa and calcium.
  Proceedings of the National Academy of Sciences of the United States of America 1983 Rodgers GM, Shuman MA
• Characterization of the effects of cultured vascular cells on the activation of blood coagulation.
  Blood 1983 Rodgers GM, Greenberg CS, Shuman MA
• Radioisotopic measurement of plasma kallikrein.
  Thrombosis research 1982 Rodgers GM, Donaldson VH, Shuman MA
• Acquired cyclic neutropenia: successful treatment with prednisone.
  American journal of hematology 1982 Rodgers GM, Shuman MA
• The zymogen forms of blood coagulation factor XIII bind specifically to fibrinogen.
  The Journal of biological chemistry 1982 Greenberg CS, Shuman MA
• Proliferation and differentiation of bovine corneal endothelial cells in culture.
  Metabolic, pediatric, and systemic ophthalmology 1982 Savion N, Isaacs JD, Shuman MA, Gospodarowicz D
• Effect of cell density on thrombin binding to a specific site on bovine vascular endothelial cells.
  The Journal of cell biology 1981 Isaacs J, Savion N, Gospodarowicz D, Shuman MA
• Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells.
  The Journal of biological chemistry 1981 Savion N, Isaacs JD, Gospodarowicz D, Shuman MA
• Covalent binding of thrombin to specific sites on corneal endothelial cells.
  Biochemistry 1981 Isaacs JD, Savion N, Gospodarowicz D, Fenton JW, Shuman MA
• Combined idiopathic neutropenia and thrombocytopenia: evidence for an immune basis for the syndrome.
  Annals of internal medicine 1980 Linker CA, Newcom SR, Nilsson CM, Wolf JL, Shuman MA
• Relationship between secretion of platelet Factor 4 and thrombin generation during in vitro blood clotting.
  The Journal of clinical investigation 1980 Shuman MA, Levine SP
• Synthesis of plasminogen activator by bovine corneal endothelial cells.
  Experimental eye research 1979 Fehrenbacher L, Gospodarowicz D, Shuman MA
• Thrombin-induced platelet secretion. Further evidence for a specific pathway.
  The Journal of clinical investigation 1979 Shuman MA, Botney M, Fenton JW
• The isolation of vascular endothelial cell lines with altered cell surface and platelet-binding properties.
  Cell 1978 Zetter BR, Johnson LK, Shuman MA, Gospodarowicz D
• Thrombin generation and secretion of platelet Factor 4 during blood clotting.
  The Journal of clinical investigation 1978 Shuman MA, Levine SP
• The measurement of thrombin in clotting blood by radioimmunoassay.
  The Journal of clinical investigation 1976 Shuman MA, Majerus PW
• The binding of human and bovine thrombin to human platelets.
  Blood 1976 Shuman MA, Tollefsen DM, Majerus PW
• Letter: Polycythemia vera and acute leukemia.
  Annals of internal medicine 1975 Neu LT, Shuman MA, Brown EB
• The perturbation of thrombin binding to human platelets by anions.
  The Journal of clinical investigation 1975 Shuman MA, Majerus PW
• Characteristics of the membrane defect in the hereditary stomatocytosis syndrome.
  Blood 1975 Wiley JS, Ellory JC, Shuman MA, Shaller CC, Cooper RA