Manish Mahadevan
Clinical Research Coordinator
Medicine
School of Medicine

Publications (33)

Top publication keywords:
ConnexinsRNA-Binding ProteinsMuscle DevelopmentMusclesChloride ChannelsMyotonin-Protein KinaseHomeodomain ProteinsRNA3' Untranslated RegionsAlternative SplicingMyotonic DystrophyRNA, MessengerTumor Necrosis FactorsMuscle, SkeletalOligonucleotides, Antisense

• Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration.
  International journal of molecular sciences 2024 Yadava RS, Mandal M, Mahadevan MS
• Detecting RNA-Protein Interactions With EGFP-Cy3 FRET by Acceptor Photobleaching.
  Current protocols 2023 Alam SR, Mahadevan MS, Periasamy A
• Cardiac Pathology in Myotonic Dystrophy Type 1.
  International journal of molecular sciences 2021 Mahadevan MS, Yadava RS, Mandal M
• Modeling muscle regeneration in RNA toxicity mice.
  Human molecular genetics 2021 Yadava RS, Mandal M, Giese JM, Rigo F, Bennett CF, Mahadevan MS
• Systemic therapy in an RNA toxicity mouse model with an antisense oligonucleotide therapy targeting a non-CUG sequence within the DMPK 3'UTR RNA.
  Human molecular genetics 2020 Yadava RS, Yu Q, Mandal M, Rigo F, Bennett CF, Mahadevan MS

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• Mismatch Repair Protein Deficiency/Microsatellite Instability Is Rare in Cholangiocarcinomas and Associated With Distinctive Morphologies.
  American journal of clinical pathology 2020 Ju JY, Dibbern ME, Mahadevan MS, Fan J, Kunk PR, Stelow EB
• Atypical Lymphoid Proliferations and Clonality in Helicobacter-associated Inflammatory Infiltrates in Children.
  The American journal of surgical pathology 2019 Ju JY, Stelow EB, Mahadevan MS, Fan J, Aguilera NS
• MBNL1 overexpression is not sufficient to rescue the phenotypes in a mouse model of RNA toxicity.
  Human molecular genetics 2019 Yadava RS, Kim YK, Mandal M, Mahadevan K, Gladman JT, Yu Q, Mahadevan MS
• Universal Lynch Syndrome Screening Should be Performed in All Upper Tract Urothelial Carcinomas.
  The American journal of surgical pathology 2018 Ju JY, Mills AM, Mahadevan MS, Fan J, Culp SH, Thomas MH, Cathro HP
• Phase determination using chromosomal microarray and fluorescence in situ hybridization in a patient with early onset Parkinson disease and two deletions in PRKN.
  Molecular genetics & genomic medicine 2018 Williams ES, Barrett MJ, Dhamija R, Toran L, Chambers C, Mahadevan MS, Golden WL
• Detection of synchronous primary lung adenocarcinomas with genomic sequencing.
  Annals of diagnostic pathology 2018 Berry D, Mahadevan M, Wick MR
• Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase Cβ.
  PloS one 2016 Kim YK, Yadava RS, Mandal M, Mahadevan K, Yu Q, Leitges M, Mahadevan MS
• TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity.
  PloS one 2016 Yadava RS, Foff EP, Yu Q, Gladman JT, Zheng TS, Mahadevan MS
• Multiple cutaneous lymphoproliferative disorders showing a retained tumor clone by T-cell receptor gene rearrangement analysis: a case series of four patients and review of the literature.
  International journal of dermatology 2015 Stowman AM, Hsia LL, Kanner WA, Mahadevan MS, Bullock GC, Patterson JW
• TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy.
  Human molecular genetics 2014 Yadava RS, Foff EP, Yu Q, Gladman JT, Kim YK, Bhatt KS, Thornton CA, Zheng TS, Mahadevan MS
• NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.
  Human molecular genetics 2014 Gladman JT, Yadava RS, Mandal M, Yu Q, Kim YK, Mahadevan MS
• Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1).
  PloS one 2014 Rehman S, Gladman JT, Periasamy A, Sun Y, Mahadevan MS
• Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).
  PloS one 2013 Gladman JT, Mandal M, Srinivasan V, Mahadevan MS
• Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity.
  Human molecular genetics 2013 Kim YK, Mandal M, Yadava RS, Paillard L, Mahadevan MS
• Myotonic dystrophy: is a narrow focus obscuring the rest of the field?
  Current opinion in neurology 2012 Mahadevan MS
• The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing.
  The Journal of cell biology 2012 Ravel-Chapuis A, Bélanger G, Yadava RS, Mahadevan MS, DesGroseillers L, Côté J, Jasmin BJ
• Therapeutics development in myotonic dystrophy type 1.
  Muscle & nerve 2011 Foff EP, Mahadevan MS
• Myotonic muscular dystrophy, RNA toxicity, and the brain: trouble making the connection?
  Cell stem cell 2011 Mahadevan MS
• Genetics. Exposing a DUX tale.
  Science (New York, N.Y.) 2010 Mahadevan MS
• The effect of myotonic dystrophy transcript levels and location on muscle differentiation.
  Biochemical and biophysical research communications 2008 Mastroyiannopoulos NP, Chrysanthou E, Kyriakides TC, Uney JB, Mahadevan MS, Phylactou LA
• Detection of immunoglobulin heavy chain gene rearrangements in classic hodgkin lymphoma using commercially available BIOMED-2 primers.
  Diagnostic molecular pathology : the American journal of surgical pathology, part B 2008 Chute DJ, Cousar JB, Mahadevan MS, Siegrist KA, Silverman LM, Stoler MH
• RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression.
  Nature genetics 2007 Yadava RS, Frenzel-McCardell CD, Yu Q, Srinivasan V, Tucker AL, Puymirat J, Thornton CA, Prall OW, Harvey RP, Mahadevan MS
• Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.
  Nature genetics 2006 Mahadevan MS, Yadava RS, Yu Q, Balijepalli S, Frenzel-McCardell CD, Bourne TD, Phillips LH
• Factor V null mutation affecting the Roche LightCycler factor V Leiden assay.
  Clinical chemistry 2005 Mahadevan MS, Benson PV
• Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3' untranslated region transcripts.
  EMBO reports 2005 Mastroyiannopoulos NP, Feldman ML, Uney JB, Mahadevan MS, Phylactou LA
• Genotype-phenotype correlations: assessing the influence of sequence variants on the clinical phenotype.
  Clinical chemistry 2005 Silverman LM, Mahadevan MS
• Myogenic defects in myotonic dystrophy.
  Developmental biology 2004 Amack JD, Mahadevan MS
• Mutant DMPK 3'-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD.
  The Journal of cell biology 2002 Amack JD, Reagan SR, Mahadevan MS