Lynne Neumayr, MD
Clinical Professor
Pediatrics
School of Medicine

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Publications (64)

Top publication keywords:
Monitoring, PhysiologicStem Cell TransplantationTherapies, InvestigationalFemur NeckMedical Records Systems, ComputerizedAnemia, Sickle CellThalassemiaGlutamineFemur Head NecrosisHydroxyureaAntisickling AgentsOsteonecrosisPneumonia, MycoplasmaIron Chelating AgentsErythrocyte Transfusion

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  • The Grndad Registry: Contemporary Natural History Data and an Analysis of Real-World Patterns of Use and Limitations of Disease Modifying Therapy in Adults with SCD.
    Blood 2020 Alexandra Boye-Doe, Elizabeth Brown, Charu Puri-Sharma, Anjulika Chawla, Joshua J Field, Lynne D. Neumayr, Susan Padrino, Payal Desai, Deepa Manwani, Sophie M. Lanzkron, Jane A. Little
  • Osteonecrosis in sickle cell disease: an update on risk factors, diagnosis, and management.
    Hematology. American Society of Hematology. Education Program 2019 Adesina OO, Neumayr LD
  • Chronic Kidney Disease Is Under-Screened in SCD and Mild Albuminuria Is Associated with a Drop in Hemoglobin: A Report from the Grndad Sickle Cell Registry.
    Blood 2019 Elizabeth Williams, Elizabeth Brown, Deepa Manwani, Payal Desai, Joshua J. Field, Lynne D. Neumayr, Susan Padrino, E. Leila Jerome Clay, Ze Cong, Irene Agodoa, Carolyn Hoppe, Sophie M. Lanzkron, Jane …
  • Clinical Practice Patterns for Hydroxyurea Initiation in Young Children with Sickle Cell Disease.
    Blood 2019 Anna M Hood, Yolanda Johnson, Cara Nwankwo, Lisa M Shook, Aimee K Hildenbrand, Allison A. King, Kim Smith-Whitley, Sherif M. Badawy, Alexis A Thompson, Susan E Creary, Connie M. Piccone, Lynne D. …
  • Sickle cell disease: current treatment and emerging therapies.
    The American journal of managed care 2019 Neumayr LD, Hoppe CC, Brown C
  • Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
    The Lancet. Neurology 2019 Klopstock T, Tricta F, Neumayr L, Karin I, Zorzi G, Fradette C, Kmiec T, Büchner B, Steele HE, Horvath R, Chinnery PF, Basu A, Küpper C, Neuhofer C, Kálmán B, Dušek P, Yapici Z, Wilson I, Zhao F, …
  • Sickle Cell Disease: Monitoring, Current Treatment, and Therapeutics Under Development.
    Hematology/oncology clinics of North America 2019 Hoppe C, Neumayr L
  • Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial).
    Blood advances 2018 Daak AA, Dampier CD, Fuh B, Kanter J, Alvarez OA, Black LV, McNaull MA, Callaghan MU, George A, Neumayr L, Hilliard LM, Sancilio F, Rabinowicz AL, Heeney MM
  • A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    The New England journal of medicine 2018 Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R,…
  • Systemic Biomarkers Show Elevated Oxidative Stress and Chronic Inflammation in Two Disorders of Neurodegeneration with Brain Iron Accumulation (NBIA).
    Blood 2017 Michael Minkley, Nancy Sweeters, Shiva Kasravi, Jennifer Ferguson, Annie Higa, Angela Jackson, Derek Smith, Christoph Borchers, Raad Nashmi, Patrick Macleod, Lynne D. Neumayr, Elliott Vichinsky, …
  • Encephaloduroarteriosynangiosis (EDAS) in young patients with cerebrovascular complications of sickle cell disease: Single-institution experience.
    Pediatric hematology and oncology 2017 Winstead M, Sun PP, Martin K, Earl J, Neumayr L, Hoppe C, Vichinsky E
  • Emergency department utilization by Californians with sickle cell disease, 2005-2014.
    Pediatric blood & cancer 2016 Paulukonis ST, Feuchtbaum LB, Coates TD, Neumayr LD, Treadwell MJ, Vichinsky EP, Hulihan MM
  • Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke.
    British journal of haematology 2016 Dowling MM, Quinn CT, Ramaciotti C, Kanter J, Osunkwo I, Inusa B, Iyer R, Kwiatkowski JL, Johnson C, Rhodes M, Owen W, Strouse JJ, Panepinto JA, Neumayr L, Sarnaik S, Plumb PA, Dlamini N, Kirkham F, …
  • Erythrocytapheresis for chronic transfusion therapy in sickle cell disease: survey of current practices and review of the literature.
    Transfusion 2016 Kelly S, Quirolo K, Marsh A, Neumayr L, Garcia A, Custer B
  • 278 Emergency Department Utilization by Californians With Sickle Cell Disease, 2005-2014.
    Annals of Emergency Medicine 2016 S. Paulukonis, E. Vichinsky, L. Neumayr, M. Treadwell, T. Coates, L. Feuchtbaum, M. Hulihan
  • Stroke recurrence in adult sickle cell patients: it is time for action!
    Transfusion 2016 Neumayr L, Vichinsky E
  • Iron Level and Monocyte Morphology Predict TLR4 Expression and Reactive Oxygen Species Production Which Influences Chronic Inflammation in ß-Thalassemia.
    Blood 2015 Patrick B. Walter, Nick Slater, Paul Harmatz, Annie Higa, Vivian Ng, Marcels Weyhmiller, Patricia Evans, John B Porter, Nancy Sweeters, Jackson Price, David Killilea, Lynne Neumayr, Ashutosh Lal, …
  • Abstract T P369: Increased Prevalence of Potential Right-to-Left Shunting in Children with Sickle Cell Anemia and Stroke.
    Stroke 2015 Michael M Dowling, Claudio Ramaciotti, Julie Kanter, Ifeyinwa Osunkwo, Baba Inusa, Rathy Iyer, Janet Kwiatkowski, Clarissa Johnson, Melissa M Rhodes, William Owen, John J Strouse, Charles Quinn, Julie…
  • 138 Iron Overload and Hemolysis Modulate Monocytes and Inflammation in ß-Thalassemia.
    Free Radical Biology and Medicine 2014 Nicholas Richard Slater, Paul Harmatz, Annie Higa, Vivian Ng, Marcela G G Weyhmiller, Patricia Evans, John B Porter, Nancy Sweeters, Jackson Price, Alisha Manji, Angela Manocha, David W Killilea, …
  • Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.
    British journal of haematology 2014 Porter JB, Walter PB, Neumayr LD, Evans P, Bansal S, Garbowski M, Weyhmiller MG, Harmatz PR, Wood JC, Miller JL, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, …
  • Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH).
    Pediatric blood & cancer 2014 Paulukonis ST, Harris WT, Coates TD, Neumayr L, Treadwell M, Vichinsky E, Feuchtbaum LB
  • Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition.
    Neurology 2014 Mackin RS, Insel P, Truran D, Vichinsky EP, Neumayr LD, Armstrong FD, Gold JI, Kesler K, Brewer J, Weiner MW, Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group
  • Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study).
    Blood 2013 John Porter, Patrick B Walter, Lynne D Neumayr, Patricia Evans, Marcela G Weyhmiller, Paul Harmatz, John C. Wood, Jeffery L Miller, Guenter Weiss, Quing Yuan, Zhiyue J Wang, Regine Grosse, Bjoern P …
  • Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME).
    Transfusion 2013 Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA, CDC Thalassemia Investigators
  • A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes.
    Haematologica 2013 Morris CR, Kuypers FA, Lavrisha L, Ansari M, Sweeters N, Stewart M, Gildengorin G, Neumayr L, Vichinsky EP
  • A Randomized, Open-Label, Multicenter, Dose Escalation Study of HQK-1001 (2,2-Dimethylbutyrate, Sodium Salt) in Sickle Cell Disease.
    Blood 2012 Abdullah Kutlar, Marvin Reid, Ali T Taher, Adlette Inati, Miguel R. Abboud, Amal El-Beshlawy, George R. Buchanan, Hedy Smith, Kenneth I. Ataga, Nebu Koshy, Lynne D Neumayr, Punam Malik, Ofelia A. …
  • Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia.
    Blood 2012 John B. Porter, Patrick B Walter, Lynne D Neumayr, Patricia Evans, Marcela G Weyhmiller, Paul Harmatz, John C Wood, Jeffery L. Miller, Guenter Weiss, Qing Yuan, Zhiyue J Wang, Regine Grosse, Bjoern P …
  • Combined chelation therapy with deferasirox and deferoxamine in thalassemia.
    Blood cells, molecules & diseases 2012 Lal A, Porter J, Sweeters N, Ng V, Evans P, Neumayr L, Kurio G, Harmatz P, Vichinsky E
  • A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease.
    American journal of hematology 2012 Kutlar A, Ataga K, Reid M, Vichinsky EP, Neumayr L, Blair-Britt L, Labotka R, Glass J, Keefer JR, Wargin WA, Berenson R, Perrine SP
  • A Phase 2 Clinical Study of HQK-1001 (2,2-dimethylbutyrate, sodium salt), a Fetal Hemoglobin Inducer, in Patients with Sickle Cell Disease.
    Blood 2011 Abdullah Kutlar, Adlette Inati, Ali T Taher, Amal El-Beshlawy, Marvin Reid, Miguel R. Abboud, Hedy Smith, Kenneth I. Ataga, George R. Buchanan, Punam Malik, Nebu Koshy, Lynne Neumayr, Maria Aiello, …
  • Transfusion Complications in Thalassemia: A Report From the Centers for Disease Control and Prevention (CDC).
    Blood 2011 Elliott Vichinsky, Lynne Neumayr, Sean Trimble, Alexis A. Thompson, Patricia Giardina, Alan R. Cohen, Thomas D. Coates, Ellis J. Neufeld, Althea M Grant, Jeanne Boudreaux
  • Red blood cell transfusion in pediatric patients with severe chronic anemia: how slow is necessary?
    Pediatric blood & cancer 2011 Agrawal AK, Hsu E, Quirolo K, Neumayr LD, Flori HR
  • Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes.
    Experimental biology and medicine (Maywood, N.J.) 2011 Kanathezhath B, Mizokami M, Stanislaus S, Hounshell C, Neumayr L, Guo H, Hearst JE, Walters MC, Kuypers FA
  • The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial.
    British journal of haematology 2011 Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K
  • A New Method of Hip Coring Decompression for the Treatment of Femoral Avascular Necrosis In Sickle Cell Disease: Perioperative Safety and Preliminary Efficacy Data.
    Blood 2010 Rakesh Donthineni, Janice Earl, Lynne Neumayr, Robert W Hagar, Keith C. Quirolo, Christine Aguilar, Elliott Vichinsky
  • A Randomized Trial of the Safety and Benefit of Transfusion Vs. Standard Care In the Prevention of Sickle Cell-Related Complications In Adults: a Preliminary Report From the Phase II NHLBI Comprehensive Sickle Cell Centers (CSCC) Study of Neuropsychological Dysfunction and Neuroimaging Abnormalities In Neurologically Intact Adult Patients with Sickle Cell Disease.
    Blood 2010 Elliott Vichinsky, Lynne Neumayr, Jeffrey I Gold, Michael W Weiner, Jeffrey Kasten, Diana Truran, Cathie Snyder, Karen Kesler, Atif Mahmoud Hussein, Thomas J. Harrington, Lillian McMahon, Victor R. …
  • Combined Chelation Therapy with Deferasirox and Deferoxamine In Transfusion-Dependent Thalassemia.
    Blood 2010 Ashutosh Lal, Nancy Sweeters, Vivian Ng, Drucilla Foote, Patricia Evans, Lynne Neumayr, Gregory Kurio, Paul Harmatz, John B. Porter, Elliott Vichinsky
  • Emergency Room Utilization by California Sickle Cell Patients During Pediatric to Adult Care Transition.
    Blood 2010 Susan Paulukonis, Lynne Neumayr, Thomas D. Coates, Elliott Vichinsky, Lisa Feuchtbaum
  • Phase 1/2 Clinical Trial of HQK-1001, An Oral Fetal Hemoglobin Stimulant, In Sickle Cell Anemia.
    Blood 2010 Abdullah Kutlar, Kenneth I. Ataga, Marvin Reid, Loray A Blair-Britt, Elliott Vichinsky, Lynne Neumayr, Richard J. Labotka, Jonathan Glass, Andrea Small-WIlliams, Jeffrey Keefer, Ling Shen, Michael S …
  • Chart Card: feasibility of a tool for improving emergency department care in sickle cell disease.
    Journal of the National Medical Association 2010 Neumayr L, Pringle S, Giles S, Quirolo KC, Paulukonis S, Vichinsky EP, Treadwell MJ
  • Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia.
    JAMA 2010 Vichinsky EP, Neumayr LD, Gold JI, Weiner MW, Rule RR, Truran D, Kasten J, Eggleston B, Kesler K, McMahon L, Orringer EP, Harrington T, Kalinyak K, De Castro LM, Kutlar A, Rutherford CJ, Johnson C, …
  • Augmentation Of Hematopoietic Engraftment Without Graft Versus Host Disease By “Add-Back” Of Photochemically Treated T Lymphocytes In Mismatched Cord Blood Transplantation.
    Biology of Blood and Marrow Transplantation 2010 B. Kanathezhath, L. Neumayr, H. Guo, M.C. Walters, F.A. Kuypers
  • Improved Engraftment without Graft-Versus-Host Disease After MHC-Mismatched Cord Blood Transplantation with Photochemically Treated Donor Lymphocytes.
    Blood 2009 Bindu Kanathezhath, Myra Mizokami, Lynne Neumayr, Hua Guo, Mark C. Walters, Frans A. Kuypers
  • Rate of Packed Red Blood Cell Transfusion in Pediatric Patients with Severe Chronic Anemia and Normal Cardiopulmonary Status: How Slow Is Truly Necessary?.
    Blood 2009 Anurag K. Agrawal, Edmund Hsu, Lynne Neumayr, Keith C. Quirolo, Heidi R. Flori
  • Safety of Combined Chelation Therapy with Deferasirox and Deferoxamine in Transfusion-Dependent Thalassemia.
    Blood 2009 Ashutosh Lal, Nancy Sweeters, Matt Herz, Dru Foote, Lynne Neumayr, Greg Kurio, Paul R Harmatz, Elliott P Vichinsky
  • Prolonged QTc in Sickle Cell Disease: A Potential Risk Factor for Early Death?.
    Blood 2008 Sean Lindstedt, Lynne Neumayr, Gregory Kurio, Claudia Morris, Shanda Robertson, Ellen Fung, Paul Harmatz, John C Wood, Elliott P. Vichinsky
  • Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia.
    Bone 2008 Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP, Multi-Center Iron Overload Study Group
  • Neuropsychological (NP) Dysfunction and Neuroimaging Abnormalities in Neurologically Intact Adult Patients with Sickle Cell Disease (SCD).
    Blood 2007 Elliott Vichinsky, J. Gold, R. Rule, M. Weiner, B. Eggleston, A. Muma, L. Neumayr, S. Lieff, D. Bessman, K. Kalinyak, L. De Castro, T. Harrington, A. Hussein, C. Johnson, L. McMahon, E. Orringer, C. …
  • PHYSICAL THERAPY ALONE COMPARED WITH CORE DECOMPRESSION AND PHYSICAL THERAPY FOR FEMORAL HEAD OSTEONECROSIS IN SICKLE CELL DISEASE.
    The Journal of Bone and Joint Surgery (American) 2006 LYNNE D. NEUMAYR, CHRISTINE AGUILAR, ANN N. EARLES, HARRY E. JERGESEN, CHARLES M. HABERKERN, BAMIDELE F. KAMMEN, PAUL A. NANCARROW, ERIC PADUA, MEREDITH MILET, BERNARD N. STULBERG, ROGER A. WILLIAMS, …
  • Physical therapy alone compared with core decompression and physical therapy for femoral head osteonecrosis in sickle cell disease. Results of a multicenter study at a mean of three years after treatment.
    The Journal of bone and joint surgery. American volume 2006 Neumayr LD, Aguilar C, Earles AN, Jergesen HE, Haberkern CM, Kammen BF, Nancarrow PA, Padua E, Milet M, Stulberg BN, Williams RA, Orringer EP, Graber N, Robertson SM, Vichinsky EP, National …
  • Left Ventricular Dysfunction in Chronically Transused Patients with Sickle Cell Anemia and Thalassemia.
    Blood 2006 Lynne Neumayr, Ellen Fung, Paul Harmatz, Ellen Butensky, John Wood, Claudia Morris, Shanda Robertson, Meredith Milet, Elliott Vichinsky
  • MRI Assessment of Pituitary Iron and Volume in Thalassemia, and Relation to Hypothalamic-Pituitary-Gonadal Axis Function (HPG): A Feasibility Study.
    Blood 2006 Zhiyue J. Wang, Roland Fischer, Ellen Butensky, Lynne Neumayr, Sylvia Titi Singer, Phillip Lee, Zili Chu, Jill V. Hunter, John Firebaugh, Elliott Vichinsky, Paul Harmatz
  • Reversive Loss of Pulmonary Function Induced by Acute Chest Syndrome: A Report from the National Acute Chest Syndrome Study Group (NACSG).
    Blood 2005 Lynne Neumayr, C. Morris, A. Wen, A. Earles, S. Robertson, M. Abboud, S. Ballas, I. Browning, R. Bellevue, C. Daeschner, P. Groncy, H.A. Hume, R. Iyer, L. McMahon, M. Moncino, E. Orringer, P. Swerdlow…
  • Bone and joint disease in sickle cell disease.
    Hematology/oncology clinics of North America 2005 Aguilar C, Vichinsky E, Neumayr L
  • Clinical evaluation of avascular necrosis in patients with sickle cell disease: Children's Hospital Oakland Hip Evaluation Scale--a modification of the Harris Hip Score.
    Archives of physical medicine and rehabilitation 2005 Aguilar CM, Neumayr LD, Eggleston BE, Earles AN, Robertson SM, Jergesen HE, Stulberg BN, Vichinsky EP
  • Progression of Avascular Necrosis of the Hip in Sickle Cell Disease: 2 Year Follow-Up of Randomized Trial of Aggressive Physical Therapy and Hip Coring Decompression.
    Blood 2004 Elliott P. Vichinsky, Lynne Neumayr, Ann Earles, Christine Aguilar, Shanda Robertson, Eugene Orringer, Zakia Al-Lamki, James Casella, Winfred Wang, Gloria Ramirez, Charles Daeschner, Nancy Olivieri, …
  • Mycoplasma disease and acute chest syndrome in sickle cell disease.
    Pediatrics 2003 Neumayr L, Lennette E, Kelly D, Earles A, Embury S, Groncy P, Grossi M, Grover R, McMahon L, Swerdlow P, Waldron P, Vichinsky E
  • Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease.
    Journal of pediatric hematology/oncology 2003 Dean D, Neumayr L, Kelly DM, Ballas SK, Kleman K, Robertson S, Iyer RV, Ware RE, Koshy M, Rackoff WR, Pegelow CH, Waldron P, Benjamin L, Vichinsky E, Acute Chest Syndrome Study Group
  • Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy.
    Blood 2000 Paul Harmatz, Ellen Butensky, Keith Quirolo, Roger Williams, Linda Ferrell, Thomas Moyer, Daniel Golden, Lynne Neumayr, Elliott Vichinsky