Longhui Qiu
Associate Researcher
Medicine
School of Medicine

Awards

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• Young Investigator Award, American Society of Transplantation, 2018

Education & Training

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• Postdoctoral Fellow Transplant immunology Northwestern University 08/2019
• MB Medicine Sun Yat-sen University 06/2016

Publications (20)

Top publication keywords:
SpleenInositolGraft RejectionTransplantation, HeterotopicMice, Inbred C3HPhotopheresisKidneyReperfusion InjuryDelayed Graft FunctionVirus ActivationEndoribonucleasesCytomegalovirus InfectionsGraft SurvivalVascularized Composite AllotransplantationADAM Proteins

• Decoding functional hematopoietic progenitor cells in the adult human lung.
  Research square 2024 Conrad C, Magnen M, Tsui J, Wismer H, Naser M, Venkataramani U, Samad B, Cleary SJ, Qiu L, Tian JJ, De Giovanni M, Mende N, Passegue E, Laurenti E, Combes AJ, Looney MR
• Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis.
  Acta pharmaceutica Sinica. B 2023 Zhao Q, Dong J, Liu H, Chen H, Yu H, Ye S, Yu S, Li Y, Qiu L, Song N, Xu H, Liu Q, Luo Z, Li Y, Wang R, Chen G, Jiang X
• Optimizing anesthesia and delivery approaches for dosing into lungs of mice.
  American journal of physiology. Lung cellular and molecular physiology 2023 Seo Y, Qiu L, Magnen M, Conrad C, Moussavi-Harami SF, Looney MR, Cleary SJ
• Beyond UPR: cell-specific roles of ER stress sensor IRE1α in kidney ischemic injury and transplant rejection.
  Kidney international 2023 Qiu L, Zheng X, Jaishankar D, Green R, Fang D, Nadig S, Zhang ZJ
• Pre-transplant infusion of donor leukocytes treated with extracorporeal photochemotherapy induces immune hypo-responsiveness and long-term allograft survival in murine models.
  Scientific reports 2022 Schneiderman J, Qiu L, Yeap XY, Kang X, Zheng F, Ye J, Xie Y, Wang JJ, Sambandam Y, Mathew J, Li L, Leventhal J, Edelson RL, Zhang ZJ

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• Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression.
  The Journal of clinical investigation 2022 Valet C, Magnen M, Qiu L, Cleary SJ, Wang KM, Ranucci S, Grockowiak E, Boudra R, Conrad C, Seo Y, Calabrese DR, Greenland JR, Leavitt AD, Passegué E, Méndez-Ferrer S, Swirski FK, Looney MR
• CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells.
  Science (New York, N.Y.) 2022 Liu D, Duan L, Rodda LB, Lu E, Xu Y, An J, Qiu L, Liu F, Looney MR, Yang Z, Allen CDC, Li Z, Marson A, Cyster JG
• ADAM8 signaling drives neutrophil migration and ARDS severity.
  JCI insight 2022 Conrad C, Yildiz D, Cleary SJ, Margraf A, Cook L, Schlomann U, Panaretou B, Bowser JL, Karmouty-Quintana H, Li J, Berg NK, Martin SC, Aljohmani A, Moussavi-Harami SF, Wang KM, Tian JJ, Magnen M, Valet…
• Clinical and Pathologic Feature of Patients With Early Versus Late Active Antibody-Mediated Rejection After Kidney Transplantation: A Single-Center Experience.
  Transplantation proceedings 2021 Wu Z, Qiu L, Wang C, Liu X, Li Q, Yu S, Yue Y, Li J, Chen W, Lai J, Chen L, Wang C, Chen G
• Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat.
  Journal of visualized experiments : JoVE 2020 Zheng F, Tully A, Koss KM, Zhang X, Qiu L, Wang JJ, Naved BA, Ivancic DZ, Mathew JM, Wertheim JA, Zhang ZJ
• Kidney-intrinsic factors determine the severity of ischemia/reperfusion injury in a mouse model of delayed graft function.
  Kidney international 2020 Qiu L, Lai X, Wang JJ, Yeap XY, Han S, Zheng F, Lin C, Zhang Z, Procissi D, Fang D, Li L, Thorp EB, Abecassis MM, Kanwar YS, Zhang ZJ
• MCMV Dissemination from Latently-Infected Allografts Following Transplantation into Pre-Tolerized Recipients.
  Pathogens (Basel, Switzerland) 2020 Shah S, DeBerge M, Iovane A, Yan S, Qiu L, Wang JJ, Kanwar YS, Hummel M, Zhang ZJ, Abecassis MM, Luo X, Thorp EB
• Structure-Dependent Biodistribution of Liposomal Spherical Nucleic Acids.
  ACS nano 2020 Ferrer JR, Sinegra AJ, Ivancic D, Yeap XY, Qiu L, Wang JJ, Zhang ZJ, Wertheim JA, Mirkin CA
• A novel murine model of differentiation-mediated cytomegalovirus reactivation from latently infected bone marrow haematopoietic cells.
  The Journal of general virology 2019 Liu XF, Swaminathan S, Yan S, Engelmann F, Abbott DA, VanOsdol LA, Heald-Sargent T, Qiu L, Chen Q, Iovane A, Zhang Z, Abecassis MM
• A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity.
  Journal of visualized experiments : JoVE 2019 Wang JJ, Qiu L, Fernandez R, Yeap XY, Lin CX, Zhang ZJ
• A clinically relevant murine model unmasks a "two-hit" mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2019 Zhang Z, Qiu L, Yan S, Wang JJ, Thomas PM, Kandpal M, Zhao L, Iovane A, Liu XF, Thorp EB, Chen Q, Hummel M, Kanwar YS, Abecassis MM
• Therapeutic Strategies of Kidney Transplant Ischemia Reperfusion Injury: Insight From Mouse Models.
  Biomedical journal of scientific & technical research 2019 Qiu L, Zhang ZJ
• Evaluation of quality of kidneys from donation after circulatory death/expanded criteria donors by parameters of machine perfusion.
  Nephrology (Carlton, Vic.) 2018 Chen G, Wang C, Zhao Y, Qiu L, Yuan X, Qiu J, Wang C, He X, Chen L
• The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors.
  Molecular cancer therapeutics 2017 Zhang H, Patel A, Wang YJ, Zhang YK, Kathawala RJ, Qiu LH, Patel BA, Huang LH, Shukla S, Yang DH, Ambudkar SV, Fu LW, Chen ZS
• Ethylene carbodiimide-fixed donor splenocytes combined with α-1 antitrypsin induce indefinite donor-specific protection to mice cardiac allografts.
  Transplant international : official journal of the European Society for Organ Transplantation 2017 Lai X, Qiu L, Zhao Y, Yu S, Wang C, Zhang J, Ning F, Chen L, Chen G