Lisa Winston, MD
Professor
Medicine
School of Medicine

She is the Chief of the Medical Staff and Hospital Epidemiologist at Zuckerberg San Francisco General Hospital and Trauma Center. Her research interests are infection control and prevention and antimicrobial resistant bacterial pathogens.

Education:

• AB, Harvard University, 1990
• MD, Johns Hopkins University School of Medicine, 1994

Training:

• Internal Medicine Residency, University of California, San Francisco, 1994-1997
• Chief Resident, University of California, San Francisco, 1997-1998
• Infectious Diseases Fellowship, University of California, San Francisco, 1998 – 2001
• Clinical Pharmacology Fellowship, University of California, San Francisco, 1999-2001

Certification:

• American Board of Internal Medicine, certified 1997, recertified 2007 and 2017
• American Board of Internal Medicine, subspecialty Infectious Diseases, certified 2000, recertified 2010 and 2020

Memberships & Affiliations:

• Infectious Diseases Society of America, fellow
• Society for Healthcare Epidemiology of America

• Comparative 1-Year Outcomes of Invasive Staphylococcus aureus Infections Among Persons With and Without Drug Use: An Observational Cohort Study.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin PO, Jain V
• The Evolution of a Hospital-Based Covid-19 Vaccination Program for Inpatients.
  NEJM Catalyst 2022 Dana Freiser, Merjo Roca, Tony Chung, Tanvi Bhakta, Lisa G. Winston, Gabriel M. Ortiz
• Case 36-2021: A 22-Year-Old Man with Pain and Erythema of the Left Hand.
  The New England journal of medicine 2021 Winston LG, Winkler ML, Kheterpal A, Villalba JA
• Copycat.
  The New England journal of medicine 2021 Dietz BW, Winston LG, Koehler JE, Margaretten M
• Patient-Directed Discharges Among Persons Who Use Drugs Hospitalized with Invasive Staphylococcus aureus Infections: Opportunities for Improvement.
  The American journal of medicine 2021 Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin P, Jain V
• Association between Socioeconomic Status and Incidence of Community-Associated Clostridioides difficile Infection - United States, 2014-2015.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Skrobarcek KA, Mu Y, Ahern J, Basiliere E, Beldavs ZG, Brousseau G, Dumyati G, Fridkin S, Holzbauer SM, Johnston H, Kainer MA, Meek J, Ocampo VLS, Parker E, Perlmutter R, Phipps EC, Winston L, Guh A
• Significant and sustained decrease in non-SARS-CoV-2 respiratory viral infections during COVID-19 public health interventions.
  medRxiv : the preprint server for health sciences 2021 Whitman JD, Pham P, Bern C, Dekker EM, Haller BL, Jain V, Winston LG
• 39. Comparative One-year Outcomes of Invasive staphylococcus Aureus infections Among Persons with and Without Drug Use in an Urban West Coast Cohort.
  Open Forum Infectious Diseases 2020 Ayesha Ashley Appa, Meredith Adamo, Stephenie Le, Jennifer Davis, Lisa Gail Winston, Sarah B Doernberg, Henry Chambers, Marlene Martin, Phillip Coffin, Vivek Jain
• 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital.
  Open Forum Infectious Diseases 2020 Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio …
• 496. Higher SARS-CoV-2 RT-PCR Cycle Threshold (Ct) Values Associated with Longer Symptom Duration Among Patients Hospitalized with COVID-19.
  Open Forum Infectious Diseases 2020 Lillian B Brown, Lisa Gail Winston, Barbara Haller, Phong Pham, Beatrice Marcelo, Wendy Cheung, Kara Lynch, Vivek Jain
• 780. How Much Does Prior Hospitalization Contribute to Readmission with Community-onset Clostridioides difficile Infection?.
  Open Forum Infectious Diseases 2020 Alice Guh, Lauren C Korhonen, Lisa Gail Winston, Brittany Martin, Helen Johnston, Geoffrey Brousseau, Elizabeth Basiliere, Danyel M Olson, Scott Fridkin, Lucy E Wilson, Rebecca Perlmutter, Stacy …
• Trends in U.S. Burden of Clostridioides difficile Infection and Outcomes.
  The New England journal of medicine 2020 Guh AY, Mu Y, Winston LG, Johnston H, Olson D, Farley MM, Wilson LE, Holzbauer SM, Phipps EC, Dumyati GK, Beldavs ZG, Kainer MA, Karlsson M, Gerding DN, McDonald LC, Emerging Infections Program …
• Treatment of Clostridioides difficile Infection and Non-compliance with Treatment Guidelines in Adults in 10 US Geographical Locations, 2013-2015.
  Journal of general internal medicine 2019 Novosad SA, Mu Y, Winston LG, Johnston H, Basiliere E, Olson DM, Farley MM, Revis A, Wilson L, Perlmutter R, Holzbauer SM, Whitten T, Phipps EC, Dumyati GK, Beldavs ZG, Ocampo VLS, Davis CM, Kainer M,…
• Toxin Enzyme Immunoassays Detect Clostridioides difficile Infection With Greater Severity and Higher Recurrence Rates.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Guh AY, Hatfield KM, Winston LG, Martin B, Johnston H, Brousseau G, Farley MM, Wilson L, Perlmutter R, Phipps EC, Dumyati GK, Nelson D, Hatwar T, Kainer MA, Paulick AL, Karlsson M, Gerding DN, …
• 837. Prior Hospitalizations Among Cases of Community-Associated Clostridioides difficile Infection—10 US States, 2014–2015.
  Open Forum Infectious Diseases 2019 Kelly M Hatfield, James Baggs, Lisa Gail Winston, Erin Parker, Helen Johnston, Geoff Brousseau, Danyel M Olson, Scott Fridkin, Lucy Wilson, Rebecca Perlmuter, Stacy Holzbauer, Erin C Phipps, Emily B …
• Mind the Base Rate: an Exercise in Clinical Reasoning.
  Journal of general internal medicine 2019 Aronowitz PB, Williams DM, Henderson MC, Winston LG
• Overcoming the Barrier.
  The New England journal of medicine 2018 Geha RM, Dhaliwal G, Winston LG, Kickler TS, Manesh R
• 1788. Cost-Effectiveness of Penicillin Skin Testing Among Patients With Methicillin-Sensitive Staphylococcus aureus Bacteremia and Reported Penicillin Allergy.
  Open Forum Infectious Diseases 2018 Alon Vaisman, Henry F Chambers, Lisa G Winston, Dhruv Kazi
• 482. Association between Socioeconomic Status Factors and Incidence of Community-Associated Clostridium difficile Infection Utilizing Factor Analysis—United States, 2014–2015.
  Open Forum Infectious Diseases 2018 Kimberly Skrobarcek, Yi Mu, Jennifer Ahern, Zintars Beldavs, Geoff Brousseau, Ghinwa Dumyati, Monica M Farley, Stacy Holzbauer, Marion A Kainer, James I Meek, Rebecca Perlmutter, Erin C Phipps, Lisa G…
• 490. Comparison of Clostridium difficile Infection Outcomes by Diagnostic Testing Method.
  Open Forum Infectious Diseases 2018 Alice Guh, Kelly Hatfield, Lisa G Winston, Brittany Martin, Helen Johnston, Geoff Brousseau, Monica M Farley, Lucy E Wilson, Rebecca Perlmutter, Erin C Phipps, Ghinwa Dumyati, Deborah Nelson, Trupti …
• 492. Long-Term Outcomes of Clostridium difficile Infection Among Medicare Beneficiaries.
  Open Forum Infectious Diseases 2018 Kelly M Hatfield, James Baggs, Lisa G Winston, Erin Parker, Brittany Martin, James I Meek, Danyel Olson, Monica M Farley, Andrew Revis, Stacy Holzbauer, Maria Bye, Lucy Wilson, Rebecca Perlmutter, …
• Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital.
  JAMA internal medicine 2018 Chaisson LH, Duong D, Cattamanchi A, Roemer M, Handley MA, Schillinger D, Sur M, Pham P, Lin MA, Goldman LE, Quan J, Perez S, Healy M, Higashi J, Winston L, Haller B, Luetkemeyer AF, Davis JL
• Examining the association between hospital-onset Clostridium difficile infection and multiple-bed room exposure: a case-control study.
  Infection control and hospital epidemiology 2018 Vaisman A, Jula M, Wagner J, Winston LG
• Trends in incidence of long-term-care facility onset Clostridium difficile infections in 10 US geographic locations during 2011-2015.
  American journal of infection control 2018 Guh AY, Mu Y, Baggs J, Winston LG, Bamberg W, Lyons C, Farley MM, Wilson LE, Holzbauer SM, Phipps EC, Beldavs ZG, Kainer MA, Karlsson M, Gerding DN, Dumyati G
• Risk Factors for Community-Associated Clostridium difficile Infection in Adults: A Case-Control Study.
  Open forum infectious diseases 2017 Guh AY, Adkins SH, Li Q, Bulens SN, Farley MM, Smith Z, Holzbauer SM, Whitten T, Phipps EC, Hancock EB, Dumyati G, Concannon C, Kainer MA, Rue B, Lyons C, Olson DM, Wilson L, Perlmutter R, Winston LG,…
• Association Between Hospital-Onset Clostridium difficile infection and Admission to a Multi-Bed Room: A Case–control Study.
  Open Forum Infectious Diseases 2017 Alon Vaisman, Michael Jula, Jessica Wagner, Lisa G Winston
• Socioeconomic Status Factors Associated with Increased Incidence of Community-Associated Clostridium difficile Infection.
  Open Forum Infectious Diseases 2017 Kimberly Skrobarcek, Yi Mu, Lisa G Winston, Geoff Brousseau, Carol Lyons, Monica Farley, Rebecca Perlmutter, Stacy Holzbauer, Erin C Phipps, Ghinwa Dumyati, Zintars G Beldavs, Marion Kainer, Alice Guh
• Treatment of Clostridium difficile Infection in 10 US Geographical Locations, 2013–2014.
  Open Forum Infectious Diseases 2016 Shannon Novosad, Lisa G. Winston, Helen Johnston, Elizabeth Badolato, Carol Lyons, Monica Farley, Andrew Revis, Lucy Wilson, Rebecca Perlmutter, Stacy M. Holzbauer, Tory Whitten, Erin C. Phipps, …
• Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes.
  Open forum infectious diseases 2016 Hunter JC, Mu Y, Dumyati GK, Farley MM, Winston LG, Johnston HL, Meek JI, Perlmutter R, Holzbauer SM, Beldavs ZG, Phipps EC, Dunn JR, Cohen JA, Avillan J, Stone ND, Gerding DN, McDonald LC, Lessa FC
• Risk Factors for Clostridium difficile Infection Recurrence.
  Open Forum Infectious Diseases 2015 Sujan C. Reddy, Alice Guh, Fernanda C. Lessa, Yi Mu, Zintars G. Beldavs, Corinne M. Davis, Ghinwa Dumyati, Stacy M. Holzbauer, Helen L. Johnston, Carol Lyons, Erin C. Phipps, Lucy E. Wilson, Lisa G. …
• Association Between Outpatient Antibiotic Prescribing Practices and Community-Associated Clostridium difficile Infection.
  Open forum infectious diseases 2015 Dantes R, Mu Y, Hicks LA, Cohen J, Bamberg W, Beldavs ZG, Dumyati G, Farley MM, Holzbauer S, Meek J, Phipps E, Wilson L, Winston LG, McDonald LC, Lessa FC
• Burden of Clostridium difficile infection in the United States.
  The New England journal of medicine 2015 Lessa FC, Winston LG, McDonald LC, Emerging Infections Program C. difficile Surveillance Team
• Novel handwashes are superior to soap and water in removal of Clostridium difficile spores from the hands.
  American journal of infection control 2015 Isaacson D, Haller B, Leslie H, Roemer M, Winston L
• Burden of Clostridium difficile infection in the United States.
  The New England journal of medicine 2015 Lessa FC, Mu Y, Bamberg WM, Beldavs ZG, Dumyati GK, Dunn JR, Farley MM, Holzbauer SM, Meek JI, Phipps EC, Wilson LE, Winston LG, Cohen JA, Limbago BM, Fridkin SK, Gerding DN, McDonald LC
• A Critical Evaluation of Healthcare-Associated Pneumonia and the Need for Anti-pseudomonal Therapy, Including Double Coverage.
  Current Emergency and Hospital Medicine Reports 2014 Rita P. Nguyen, Lisa G. Winston
• Determinants of Clostridium difficile Infection Incidence Across Diverse United States Geographic Locations.
  Open forum infectious diseases 2014 Lessa FC, Mu Y, Winston LG, Dumyati GK, Farley MM, Beldavs ZG, Kast K, Holzbauer SM, Meek JI, Cohen J, McDonald LC, Fridkin SK
• NAP1 strain type predicts outcomes from Clostridium difficile infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 See I, Mu Y, Cohen J, Beldavs ZG, Winston LG, Dumyati G, Holzbauer S, Dunn J, Farley MM, Lyons C, Johnston H, Phipps E, Perlmutter R, Anderson L, Gerding DN, Lessa FC
• Clostridium difficile infection among children across diverse US geographic locations.
  Pediatrics 2014 Wendt JM, Cohen JA, Mu Y, Dumyati GK, Dunn JR, Holzbauer SM, Winston LG, Johnston HL, Meek JI, Farley MM, Wilson LE, Phipps EC, Beldavs ZG, Gerding DN, McDonald LC, Gould CV, Lessa FC
• 524National estimates of incidence, recurrence, hospitalization, and death of nursing home-onset Clostridium difficile infections — United States, 2012.
  Open Forum Infectious Diseases 2014 Jennifer C. Hunter, Yi Mu, Ghinwa K. Dumyati, Monica M. Farley, Lisa G. Winston, Helen L. Johnston, James I. Meek, Lucy E. Wilson, M Stacy, Zintars G. Beldavs, Erin C. Phipps, John R. Dunn, Jessica a.…
• Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Gould CV, Edwards JR, Cohen J, Bamberg WM, Clark LA, Farley MM, Johnston H, Nadle J, Winston L, Gerding DN, McDonald LC, Lessa FC, Clostridium difficile Infection Surveillance Investigators, Centers …
• Epidemiology of community-associated Clostridium difficile infection, 2009 through 2011.
  JAMA internal medicine 2013 Chitnis AS, Holzbauer SM, Belflower RM, Winston LG, Bamberg WM, Lyons C, Farley MM, Dumyati GK, Wilson LE, Beldavs ZG, Dunn JR, Gould LH, MacCannell DR, Gerding DN, McDonald LC, Lessa FC
• Risk factors for methicillin-resistant Staphylococcus aureus in patients with community-onset and hospital-onset pneumonia.
  Respiratory medicine 2013 Wooten DA, Winston LG
• Does doxycycline protect against development of Clostridium difficile infection?
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012 Doernberg SB, Winston LG, Deck DH, Chambers HF
• Risk factors for acquisition of extended-spectrum β-lactamase-producing Escherichia coli in an urban county hospital.
  American journal of infection control 2011 Doernberg SB, Winston LG
• Predictors of pneumonia severity in HIV-infected adults admitted to an Urban public hospital.
  AIDS patient care and STDs 2011 Chew KW, Yen IH, Li JZ, Winston LG
• Coming home with MRSA.
  Archives of internal medicine 2009 Winston L, Chambers H
• Antimicrobial Resistance in Staphylococci: Mechanisms of Resistance and Clinical Implications.
  Antimicrobial Drug Resistance 2009 Lisa G. Winston, Henry F. Chambers
• CHAPTER 81 ENDOCARDITIS.
  Pharmacology and Therapeutics 2009 Lisa G. Winston, Daniel Deck, Ann F. Bolger
• Infective endocarditis in an urban medical center: association of individual drugs with valvular involvement.
  The Journal of infection 2008 Jain V, Yang MH, Kovacicova-Lezcano G, Juhle LS, Bolger AF, Winston LG
• Clinical failures of appropriately-treated methicillin-resistant Staphylococcus aureus infections.
  The Journal of infection 2008 Dombrowski JC, Winston LG
• Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis.
  The American journal of medicine 2007 Li JZ, Winston LG, Moore DH, Bent S
• False-positive culture results from patient tissue specimens due to contamination of RPMI medium with Cryptococcus albidus.
  Journal of clinical microbiology 2007 Winston LG, Roemer M, Goodman C, Haller B
• Preoperative use of mupirocin for the prevention of healthcare-associated Staphylococcus aureus infections: a cost-effectiveness analysis.
  Infection control and hospital epidemiology 2006 Young LS, Winston LG
• Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia.
  Antimicrobial agents and chemotherapy 2006 Weems JJ, Steinberg JP, Filler S, Baddley JW, Corey GR, Sampathkumar P, Winston L, John JF, Kubin CJ, Talwani R, Moore T, Patti JM, Hetherington S, Texter M, Wenzel E, Kelley VA, Fowler VG
• Modern epidemiology, prophylaxis, and diagnosis and therapy for infective endocarditis.
  Current cardiology reports 2006 Winston LG, Bolger AF
• Impact of a piperacillin-tazobactam shortage on antimicrobial prescribing and the rate of vancomycin-resistant enterococci and Clostridium difficile infections.
  Pharmacotherapy 2006 Mendez MN, Gibbs L, Jacobs RA, McCulloch CE, Winston L, Guglielmo BJ
• Impact of a formulary switch from ticarcillin-clavulanate to piperacillin-tazobactam on colonization with vancomycin-resistant enterococci.
  American journal of infection control 2004 Winston LG, Charlebois ED, Pang S, Bangsberg DR, Perdreau-Remington F, Chambers HF
• Introduction of a waterless hand gel was associated with a reduced rate of ventilator-associated pneumonia in a surgical intensive care unit.
  Infection control and hospital epidemiology 2004 Winston LG, Felt SC, Huang WH, Chambers HF
• Clinical, epidemiologic, and molecular evaluation of a clonal outbreak of methicillin-resistant Staphylococcus aureus infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004 Young LS, Perdreau-Remington F, Winston LG
• API 20 strep identification system may incorrectly speciate enterococci with low level resistance to vancomycin.
  Diagnostic microbiology and infectious disease 2004 Winston LG, Pang S, Haller BL, Wong M, Chambers HF, Perdreau-Remington F
• Mupirocin prophylaxis misses by a nose.
  Annals of internal medicine 2004 Chambers HF, Winston LG
• Once-daily dosing of aminoglycosides: how much monitoring is truly required?
  The American journal of medicine 2003 Winston L, Benowitz N
• Epidemiology of vancomycin-resistant Enterococcus faecium under a selective isolation policy at an urban county hospital.
  American journal of infection control 2002 Winston LG, Bangsberg DR, Chambers HF, Felt SC, Rosen JI, Charlebois ED, Wong M, Steele L, Gerberding JL, Perdreau-Remington F
• Penicillin-nonsusceptible Streptococcus pneumoniae at San Francisco General Hospital.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999 Winston LG, Perlman JL, Rose DA, Gerberding JL