Lisa Rotenstein, MD, MBA
Assistant Professor
Medicine
School of Medicine

She is an Assistant Professor and Medical Director of Ambulatory Quality and Safety at UCSF Health. She additionally serves as the inaugural director of the Center to Advance Digital Physician Practice Transformation at UCSF (ADAPT) and Director of the Center for Physician Experience and Practice Excellence, which is jointly run across UCSF and Brigham and Women's Hospital. She was named a 2022 Modern Healthcare Top 25 Emerging Leader, the 2022 New England Region SGIM Investigator of the Year, and a 2021 STAT Wunderkind.

Dr. Rotenstein's research on physician and trainee mental health, published in JAMA, JAMA Health Forum, and the Journal of General Internal Medicine has fostered increased awareness of the epidemic of depression and burnout in medical students and physicians and catalyzed action to address this public health burden. Her research on the electronic health record (EHR), published in JAMA Internal Medicine, JAMA Network Open, and JAMIA, have deepened our understanding of the role of the EHR in physician experience. She is a nationally recognized expert on gender issues in medicine, with her research and writing on this topic featured in the New England Journal of Medicine, the Harvard Business Review, and JAMA Internal Medicine.

Dr. Rotenstein currently is establishing and leading ambulatory quality efforts across the UCSF Health system in her role as Medical Director of Ambulatory Quality and Safety. She additionally leads quality and electronic inbox optimization efforts for the UCSF Department of Medicine. Previously, as Medical Director of Population Health at Brigham and Women's Hospital, she led population health and collaborative care initiatives across Brigham Health's primary care practices, which care for 150,000 patients. Prior to that, she led faculty development and wellbeing, population health, and job doability efforts for the Brigham and Women's Physicians Organization.

• Are Artificial Intelligence-Generated Replies the Answer to the Electronic Health Record Inbox Problem?
  JAMA network open 2024 Rotenstein LS, Wachter RM
• Impact of COVID-19 on Characteristics and Funding of U.S. Healthcare Startups: Retrospective Review.
  JMIR formative research 2024 Ganeshan S, Goldstein J, Sohn YJ, Pollack A, Phillips RS, Rotenstein L
• Author Correction: National Comparison of Ambulatory Physician Electronic Health Record Use Across Specialties.
  Journal of general internal medicine 2024 Holmgren A, Sinsky CA, Rotenstein L, Apathy NC
• A machine learning technology for addressing medication-related risk in older, multimorbid patients.
  The American journal of managed care 2024 Seger DL, Amato MG, Frits M, Iannaccone C, Mugal A, Chang F, Fiskio J, Volk LA, Rotenstein LS
• Electronic Health Record Usability, Satisfaction, and Burnout for Family Physicians.
  JAMA network open 2024 Holmgren AJ, Hendrix N, Maisel N, Everson J, Bazemore A, Rotenstein L, Phillips RL, Adler-Milstein J
• Exploration of Electronic Health Record Patterns of Emergency Physicians-Charting the Digital Burden.
  JAMA network open 2024 Rotenstein LS, Molina M
• Impact of response bias in three surveys on primary care providers' experiences with electronic health records.
  Journal of the American Medical Informatics Association : JAMIA 2024 Hendrix N, Maisel N, Everson J, Patel V, Bazemore A, Rotenstein LS, Holmgren AJ, Krist AH, Adler-Milstein J, Phillips RL
• National Comparison of Ambulatory Physician Electronic Health Record Use Across Specialties.
  Journal of general internal medicine 2024 Holmgren AJ, Sinsky CA, Rotenstein L, Apathy NC
• Promoting Electronic Patient-Reported Outcomes in Quality Measurement.
  Journal of general internal medicine 2024 Sandhu S, Rotenstein LS, LeBlanc TW
• Virtual Scribes and Physician Time Spent on Electronic Health Records.
  JAMA network open 2024 Rotenstein L, Melnick ER, Iannaccone C, Zhang J, Mugal A, Lipsitz SR, Healey MJ, Holland C, Snyder R, Sinsky CA, Ting D, Bates DW
• Comparison of Hospital Mortality and Readmission Rates by Physician and Patient Sex.
  Annals of internal medicine 2024 Miyawaki A, Jena AB, Rotenstein LS, Tsugawa Y
• Looking Beyond Mortality Prediction: Primary Care Physician Views of Patients' Palliative Care Needs Predicted by a Machine Learning Tool.
  Applied clinical informatics 2024 Rotenstein L, Wang L, Zupanc SN, Penumarthy A, Laurentiev J, Lamey J, Farah S, Lipsitz S, Jain N, Bates DW, Zhou L, Lakin JR
• Teamwork Climate, Safety Climate, and Physician Burnout: A National, Cross-Sectional Study.
  Joint Commission journal on quality and patient safety 2024 Rotenstein L, Wang H, West CP, Dyrbye LN, Trockel M, Sinsky C, Shanafelt T
• Customised knowledge-sharing platform to foster resident quality improvement activities, tracking and scholarship.
  BMJ open quality 2024 Rowe KA, Carbo A, Katz JT, Rotenstein L
• A Window Into Inpatient Health Care Delivery Through Secure Message Logs-Tracing the Latest Breadcrumbs of the Electronic Health Record.
  JAMA network open 2023 Rotenstein LS, Sen S
• The Electronic Inbox-Benefits, Questions, and Solutions for the Road Ahead.
  JAMA 2023 Rotenstein LS, Landman A, Bates DW
• Proportion Of Preventive Primary Care Visits Nearly Doubled, Especially Among Medicare Beneficiaries, 2001-19.
  Health affairs (Project Hope) 2023 Rotenstein LS, Mafi JN, Landon BE
• System-Level Factors and Time Spent on Electronic Health Records by Primary Care Physicians.
  JAMA network open 2023 Rotenstein LS, Holmgren AJ, Horn DM, Lipsitz S, Phillips R, Gitomer R, Bates DW
• Quantifying EHR and Policy Factors Associated with the Gender Productivity Gap in Ambulatory, General Internal Medicine.
  Journal of general internal medicine 2023 Li H, Rotenstein L, Jeffery MM, Paek H, Nath B, Williams BL, McLean RM, Goldstein R, Nuckols TK, Hoq L, Melnick ER
• Identifying and Addressing Barriers to Implementing Core Electronic Health Record Use Metrics for Ambulatory Care: Virtual Consensus Conference Proceedings.
  Applied clinical informatics 2023 Levy DR, Moy AJ, Apathy N, Adler-Milstein J, Rotenstein L, Nath B, Rosenbloom ST, Kannampallil T, Mishuris RG, Alexanian A, Sieja A, Hribar MR, Patel JS, Sinsky CA, Melnick ER
• Trends in Scientific Collaboration Between Men and Women Following the #MeToo Movement.
  Journal of general internal medicine 2023 Zimerman A, Rotenstein LS, Jena AB
• Uncovering Hidden Racial and Ethnic Bias Through Electronic Health Record Logs.
  JAMA network open 2023 Rotenstein LS, Figueroa JF
• COVID exacerbated the gender disparity in physician electronic health record inbox burden.
  Journal of the American Medical Informatics Association : JAMIA 2023 Rotenstein L, Jay Holmgren A
• Association of Primary Care Physicians' Electronic Inbox Activity Patterns with Patients' Likelihood to Recommend the Physician.
  Journal of general internal medicine 2023 Rotenstein LS, Melnick ER, Jeffery M, Zhang J, Sinsky CA, Gitomer R, Bates DW
• Ctrl-C: a cross-sectional study of the electronic health record usage patterns of US oncology clinicians.
  JNCI cancer spectrum 2023 Sinha S, Holmgren AJ, Hong JC, Rotenstein LS
• Enhancing Lactation Accommodations for Physicians-An Opportunity for Tangible Investments in Our Workforce.
  JAMA network open 2023 Rotenstein LS, Del Carmen MG, Dudley J
• Pursuing Gender Equity by Paying for What Matters in Primary Care.
  The New England journal of medicine 2023 Rotenstein L, Gitomer R, Landon B
• Comparison of Work Patterns Between Physicians and Advanced Practice Practitioners in Primary Care and Specialty Practice Settings.
  JAMA network open 2023 Rotenstein LS, Apathy N, Edgman-Levitan S, Landon B
• The Association of Work Overload with Burnout and Intent to Leave the Job Across the Healthcare Workforce During COVID-19.
  Journal of general internal medicine 2023 Rotenstein LS, Brown R, Sinsky C, Linzer M
• Variation in Family Physicians' Experiences Across Different Electronic Health Record Platforms: a Descriptive Study.
  Journal of general internal medicine 2023 Hendrix N, Bazemore A, Holmgren AJ, Rotenstein LS, Eden AR, Krist AH, Phillips RL
• Association of Clinician Practice Ownership With Ability of Primary Care Practices to Improve Quality Without Increasing Burnout.
  JAMA health forum 2023 Rotenstein LS, Cohen DJ, Marino M, Bates DW, Edwards ST
• Adult Primary Care Physician Visits Increasingly Address Mental Health Concerns.
  Health affairs (Project Hope) 2023 Rotenstein LS, Edwards ST, Landon BE
• Disparities According to Genetic Ancestry in the Use of Precision Oncology Assays.
  The New England journal of medicine 2023 Mata DA, Rotenstein LS, Ramos MA, Jena AB
• Physician Note Composition Patterns and Time on the EHR Across Specialty Types: a National, Cross-sectional Study.
  Journal of general internal medicine 2022 Rotenstein LS, Apathy N, Holmgren AJ, Bates DW
• Documentation dynamics: Note composition, burden, and physician efficiency.
  Health services research 2022 Apathy NC, Rotenstein L, Bates DW, Holmgren AJ
• Association Between Electronic Health Record Time and Quality of Care Metrics in Primary Care.
  JAMA network open 2022 Rotenstein LS, Holmgren AJ, Healey MJ, Horn DM, Ting DY, Lipsitz S, Salmasian H, Gitomer R, Bates DW
• Variation in Support for Documentation Among Primary Care Physicians by Gender.
  Journal of the American Board of Family Medicine : JABFM 2022 Rotenstein LS, Apathy NC, Bates DW, Landon B
• Gender Differences in National Institutes of Health Grant Submissions Before and During the COVID-19 Pandemic.
  Journal of women's health (2002) 2022 Roubinov D, Haack LM, Folk JB, Rotenstein L, Accurso EC, Dahiya P, Ponce AN, Nava V, Maldonado Y, Linos E, Mangurian C
• Addressing Well-being Throughout the Health Care Workforce: The Next Imperative.
  JAMA 2022 Rotenstein LS, Berwick DM, Cassel CK
• A Learning Health System Agenda for Organizational Approaches to Enhancing Occupational Well-being Among Clinicians.
  JAMA 2022 Rotenstein LS, Melnick ER, Sinsky CA
• Patterns in Actions Against Physician Licenses Related to Substance Use and Psychological or Physical Impairment in the US From 2004 to 2020.
  JAMA health forum 2022 Rotenstein LS, Dadlani A, Cleary J, Sen S, Jena AB, Mata DA
• Association between state-level malpractice environment and clinician electronic health record (EHR) time.
  Journal of the American Medical Informatics Association : JAMIA 2022 Holmgren AJ, Rotenstein L, Downing NL, Bates DW, Schulman K
• Assessment of Satisfaction With the Electronic Health Record Among Physicians in Physician-Owned vs Non-Physician-Owned Practices.
  JAMA network open 2022 Rotenstein LS, Apathy N, Landon B, Bates DW
• Gender Differences in Time Spent on Documentation and the Electronic Health Record in a Large Ambulatory Network.
  JAMA network open 2022 Rotenstein LS, Fong AS, Jeffery MM, Sinsky CA, Goldstein R, Williams B, Melnick ER
• How to Measure Progress in Addressing Physician Well-being: Beyond Burnout.
  JAMA 2021 Rotenstein LS, Sinsky C, Cassel CK
• Primary Care Practice Transformation in the Era of COVID-19 and Beyond: Key Principles for General Internal Medicine Practitioners.
  Journal of general internal medicine 2021 Schmidt S, Gupta R, Bracey J, Volerman A, Henry T, Jackson C, Levine D, Jones D, Richter JM, Schmidt J, Rotenstein L, Berger Z, Peairs K, Singh H, Schwartz M, Bailey J, Goodson J
• Experiences of Work-Family Conflict and Mental Health Symptoms by Gender Among Physician Parents During the COVID-19 Pandemic.
  JAMA network open 2021 Frank E, Zhao Z, Fang Y, Rotenstein LS, Sen S, Guille C
• Beyond burnout: Understanding the well-being gender gap in general surgery by examining professional fulfillment and control over schedule.
  American journal of surgery 2021 Mete M, Dickman J, Rowe S, Trockel MT, Rotenstein L, Khludenev G, Marchalik D
• Contributors to Gender Differences in Burnout and Professional Fulfillment: A Survey of Physician Faculty.
  Joint Commission journal on quality and patient safety 2021 Rotenstein L, Harry E, Wickner P, Gupte A, Neville BA, Lipsitz S, Cullen E, Rozenblum R, Sequist TD, Dudley J
• Development of a Primary Care Transitions Clinic in an Academic Medical Center.
  Journal of general internal medicine 2021 Rotenstein L, Melia C, Samal L, Pollack S, Yu N, Cunningham R, Price C
• Differences in Clinician Electronic Health Record Use Across Adult and Pediatric Primary Care Specialties.
  JAMA network open 2021 Rotenstein LS, Holmgren AJ, Downing NL, Longhurst CA, Bates DW
• The Think Tank: An Organizational Framework to Enable Resident-Led Quality Improvement and Wellness Project Innovation.
  Journal of graduate medical education 2021 Foote MB, Jain N, Wang P, Rotenstein L, Yialamas MA, Katz JT
• Differences in Total and After-hours Electronic Health Record Time Across Ambulatory Specialties.
  JAMA internal medicine 2021 Rotenstein LS, Holmgren AJ, Downing NL, Bates DW
• Differences in Gender Representation in the Altmetric Top 100.
  Journal of general internal medicine 2021 Rotenstein LS, Torre M, Cleary JL, Sen S, Guille C, Mata DA
• Making Doctors Effective Managers and Leaders: A Matter of Health and Well-Being.
  Academic medicine : journal of the Association of American Medical Colleges 2021 Rotenstein LS, Huckman RS, Cassel CK
• Addressing Workforce Diversity - A Quality-Improvement Framework.
  The New England journal of medicine 2021 Rotenstein LS, Reede JY, Jena AB
• Sex Differences in Salaries of Department Chairs at Public Medical Schools.
  JAMA internal medicine 2020 Mensah M, Beeler W, Rotenstein L, Jagsi R, Spetz J, Linos E, Mangurian C
• Substantial Overlap Between Factors Predicting Symptoms of Depression and Burnout Among Medical Interns.
  Journal of general internal medicine 2020 Rotenstein LS, Zhao Z, Mata DA, Guille C, Sen S
• Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center.
  Circulation. Heart failure 2019 Eberly LA, Richterman A, Beckett AG, Wispelwey B, Marsh RH, Cleveland Manchanda EC, Chang CY, Glynn RJ, Brooks KC, Boxer R, Kakoza R, Goldsmith J, Loscalzo J, Morse M, Lewis EF, Abel S, Adams A, Anaya…
• Chronic Comorbidity Among Patients With Cancer: An Impetus for Oncology and Primary Care Collaboration.
  JAMA oncology 2019 Rotenstein LS, Zhang Y, Jacobson JO
• An Academic Medical Center-Based Incubator to Promote Clinical Innovation and Financial Value.
  Joint Commission journal on quality and patient safety 2019 Rotenstein LS, Wickner P, Hauser L, Littlefield M, Abbett S, Desrosiers J, Bates DW, Dudley J, Laskowski KR
• Preparing health professions students to lead change.
  Leadership in health services (Bradford, England) 2018 Rotenstein L, Perez K, Wohler D, Sanders S, Im D, Kazberouk A, Phillips RS
• Prevalence of Burnout Among Physicians: A Systematic Review.
  JAMA 2018 Rotenstein LS, Torre M, Ramos MA, Rosales RC, Guille C, Sen S, Mata DA
• Making the Voices of Female Trainees Heard.
  Annals of internal medicine 2018 Rotenstein LS, Berman RA, Katz JT, Yialamas MA
• Lost Taussigs - The Consequences of Gender Discrimination in Medicine.
  The New England journal of medicine 2018 Rotenstein LS, Jena AB
• Out-of-Pocket Spending Not Associated with Oral Oncolytic Survival Benefit.
  Journal of managed care & specialty pharmacy 2018 Rotenstein LS, Dusetzina SB, Keating NL
• Shared care planning: Realizing the promise of team-based person-centered care.
  Healthcare (Amsterdam, Netherlands) 2018 Ganeshan S, Gheihman G, Palmor M, Choi S, Wohler D, Rotenstein LS
• Impact of a clinical pathway tool on appropriate palliative radiation therapy for bone metastases.
  Practical radiation oncology 2017 Rotenstein LS, Kerman AO, Killoran J, Balboni TA, Krishnan MS, Taylor A, Martin NE
• Making Patients and Doctors Happier - The Potential of Patient-Reported Outcomes.
  The New England journal of medicine 2017 Rotenstein LS, Huckman RS, Wagle NW
• Implementing patient-reported outcome surveys as part of routine care: lessons from an academic radiation oncology department.
  Journal of the American Medical Informatics Association : JAMIA 2017 Rotenstein LS, Agarwal A, O'Neil K, Kelly A, Keaty M, Whitehouse C, Kalinowski B, Orio PF, Wagle N, Martin NE
• Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis.
  JAMA 2016 Rotenstein LS, Ramos MA, Torre M, Segal JB, Peluso MJ, Guille C, Sen S, Mata DA
• The critical components of an electronic care plan tool for primary care: an exploratory qualitative study.
  Journal of innovation in health informatics 2016 Rotenstein L, Tucker S, Kakoza R, Tishler L, Zai A, Wu C
• Management of refractory autoimmune hemolytic anemia via allogeneic stem cell transplantation.
  Bone marrow transplantation 2016 Rotenstein L, Nathan A, Ghobrial I, Antin J, Parnes A
• New Diagnosis Bundle: Improving Care Delivery for Patients With Newly Diagnosed Cancer.
  Journal of oncology practice 2016 Jacobson JO, Rotenstein LS, Berry LL
• Student-run free clinics: the USA's psychiatry recruitment solution?
  The lancet. Psychiatry 2016 Ramos MA, Rotenstein LS, Mata DA
• Effect of mineralocorticoid receptor blockade on hippocampal-dependent memory in adults with obesity.
  Obesity (Silver Spring, Md.) 2015 Rotenstein LS, Sheridan M, Garg R, Adler GK
• Characterization of the trunk neural crest in the bamboo shark, Chiloscyllium punctatum.
  The Journal of comparative neurology 2013 Juarez M, Reyes M, Coleman T, Rotenstein L, Sao S, Martinez D, Jones M, Mackelprang R, De Bellard ME
• Engineered endothelial cell adhesion via VCAM1 and E-selectin antibody-presenting alginate hydrogels.
  Acta biomaterialia 2012 Rafat M, Rotenstein LS, Hu JL, Auguste DT
• Dual functionalized PVA hydrogels that adhere endothelial cells synergistically.
  Biomaterials 2012 Rafat M, Rotenstein LS, You JO, Auguste DT
• Advances in diabetes thinking: a critical summary and analysis of keystone 2009.
  Diabetes technology & therapeutics 2010 Rotenstein L, Close KL
• Embryonic development of glial cells and myelin in the shark, Chiloscyllium punctatum.
  Gene expression patterns : GEP 2009 Rotenstein L, Milanes A, Juarez M, Reyes M, de Bellard ME
• Characterization of the shark myelin Po protein.
  Brain, behavior and evolution 2008 Rotenstein L, Herath K, Gould RM, de Bellard ME