Lisa Randolph, PhD
Postdoctoral Scholar
Psychiatry
School of Medicine

Publications (10)

Top publication keywords:
alpha-SynucleinRNA-Binding ProteinsSynapsesCoatomer ProteinHippocampusRNA, MessengerEndosomal Sorting Complexes Required for TransportProtein Aggregation, PathologicalAxonsNeuronsAutophagy-Related ProteinsCell BodyIntravital MicroscopyCoat Protein Complex ISubcellular Fractions

• Extracellular matrix proteolysis maintains synapse plasticity during brain development.
  Nature neuroscience 2025 Nakajo H, Cao R, Mula SA, McKetney J, Silva NJ, Li KH, Chalkley RJ, Randolph LK, Shah M, Rose IVL, Kampmann M, Swaney DL, Kirst C, Molofsky AV
• Alpha-synuclein abundance and localization are regulated by the RNA-binding protein PUMILIO1.
  Cell reports 2025 Cabaj M, Mazzara PG, Gaertner ZA, Wang R, Pauers MM, Randolph LK, Roque CG, Feeney S, Raimo S, de Prisco N, Chemiakine A, Wang X, Singh RK, Rajasekaran S, Yalamanchili HK, Miles W, Baldwin K, Zhang C,…
• Regulation of synapse density by Pumilio RNA-binding proteins.
  Cell reports 2024 Randolph LK, Pauers MM, Martínez JC, Sibener LJ, Zrzavy MA, Sharif NA, Gonzalez TM, Ramachandran KV, Dominguez D, Hengst U
• CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
  Science advances 2023 Gouveia Roque C, Chung KM, McCurdy EP, Jagannathan R, Randolph LK, Herline-Killian K, Baleriola J, Hengst U
• Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy.
  Neuron 2019 Fox LM, Kim K, Johnson CW, Chen S, Croce KR, Victor MB, Eenjes E, Bosco JR, Randolph LK, Dragatsis I, Dragich JM, Yoo AS, Yamamoto A

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• Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body.
  Neuron 2019 Martínez JC, Randolph LK, Iascone DM, Pernice HF, Polleux F, Hengst U
• Live Imaging of ESCRT Proteins in Microfluidically Isolated Hippocampal Axons.
  Methods in molecular biology (Clifton, N.J.) 2019 Birdsall V, Martinez JC, Randolph L, Hengst U, Waites CL
• Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons.
  EMBO reports 2018 Walker CA, Randolph LK, Matute C, Alberdi E, Baleriola J, Hengst U
• Relevance of the COPI complex for Alzheimer's disease progression in vivo.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Bettayeb K, Hooli BV, Parrado AR, Randolph L, Varotsis D, Aryal S, Gresack J, Tanzi RE, Greengard P, Flajolet M
• δ-COP modulates Aβ peptide formation via retrograde trafficking of APP.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Bettayeb K, Chang JC, Luo W, Aryal S, Varotsis D, Randolph L, Netzer WJ, Greengard P, Flajolet M