Lindsey Criswell, MD, MPH
Professor Emeritus
Medicine
School of Medicine

This work has also highlighted key biologic pathways responsible for disease onset and progression, which can inform more basic research to define the mechanism of these genetic associations. Given the heterogeneity of these disorders, we are also devoting substantial effort to the refinement of genotype-phenotype associations, such as the specificity of genetic associations for serologic or clinical subphenotypes. Several genes we have been studying, including STAT4 and TNFAIP3, are also of interest due to emerging evidence supporting their association with multiple autoimmune disorders and phenotypes. Given the strong association of the major histocompatibility complex (MHC) region with multiple autoimmune disorders, we are performing fine mapping studies of this region in order to further define the complex genetic associations of this region with SLE, RA and related phenotypes. We are also pursuing studies designed to better understand ethnic differences in autoimmune disease risk and outcome. Lastly, we have initiated several recent studies that seek to define the contribution of epigenetic factors, particularly DNA methylation patterns, to autoimmune disease risk and outcome.

• Positive psychosocial factors may protect against perceived stress in people with systemic lupus erythematosus with and without trauma history.
  Lupus science & medicine 2024 DeQuattro K, Trupin L, Patterson S, Rush S, Gordon C, Greenlund KJ, Barbour KE, Lanata C, Criswell LA, Dall'Era M, Yazdany J, Katz PP
• Screening of Environmental Chemicals to Characterize Exposures in Participants With Systemic Lupus Erythematosus.
  Arthritis & rheumatology (Hoboken, N.J.) 2024 Lanata CM, Taylor KE, Hurst-Hopf J, Nititham J, Blazer A, Trupin L, Katz P, Dall'Era M, Yazdany J, Chung SA, Abrahamsson D, Gerona R, Criswell LA
• The All of Us Research Program is an opportunity to enhance the diversity of US biomedical research.
  Nature medicine 2024 Bianchi DW, Brennan PF, Chiang MF, Criswell LA, D'Souza RN, Gibbons GH, Gilman JK, Gordon JA, Green ED, Gregurick S, Hodes RJ, Kilmarx PH, Koob GF, Koroshetz WJ, Langevin HM, Lorsch JR, Marrazzo JM, …
• Local Ancestry at the Major Histocompatibility Complex Region is Not a Major Contributor to Disease Heterogeneity in a Multiethnic Lupus Cohort.
  Arthritis & rheumatology (Hoboken, N.J.) 2024 Solomon O, Lanata CM, Adams C, Nititham J, Taylor KE, Chung SA, Yazdany J, Dall'Era M, Pons-Estel BA, Tusié-Luna T, Tsao B, Morand E, Alarcón-Riquelme ME, Barcellos LF, Criswell LA
• GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins.
  Genome biology 2023 Zhu WS, Litterman AJ, Sekhon HS, Kageyama R, Arce MM, Taylor KE, Zhao W, Criswell LA, Zaitlen N, Erle DJ, Ansel KM
• Cell-Specific Transposable Element Gene Expression Analysis Identifies Associations with Systemic Lupus Erythematosus Phenotypes.
  bioRxiv : the preprint server for biology 2023 Cutts Z, Patterson S, Maliskova L, Taylor KE, Ye C, Dall'Era M, Yazdany J, Criswell L, Fragiadakis GK, Langelier C, Capra JA, Sirota M, Lanata CM
• Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
  bioRxiv : the preprint server for biology 2023 Wiley MM, Khatri B, Joachims ML, Tessneer KL, Stolarczyk AM, Rasmussen A, Anaya JM, Aqrawi LA, Bae SC, Baecklund E, Björk A, Brun JG, Bucher SM, Dand N, Eloranta ML, Engelke F, Forsblad-d'Elia H, …
• The Back Pain Consortium (BACPAC) Research Program: Cover.
  Pain medicine (Malden, Mass.) 2023 Carter RH, Criswell LA
• The association of trauma with self-reported flares and disease activity in systemic lupus erythematosus (SLE).
  Rheumatology (Oxford, England) 2023 Katz P, Patterson SL, DeQuattro K, Lanata CM, Barbour KE, Greenlund KJ, Gordon C, Criswell LA, Dall'Era M, Yazdany J
• Medication Cost Concerns and Disparities in Patient-Reported Outcomes Among a Multiethnic Cohort of Patients With Systemic Lupus Erythematosus.
  The Journal of rheumatology 2023 Aguirre A, DeQuattro K, Shiboski S, Katz P, Greenlund KJ, Barbour KE, Gordon C, Lanata C, Criswell LA, Dall'Era M, Yazdany J
• Identification of Cell-Specific Differential DNA Methylation Associated With Methotrexate Treatment Response in Rheumatoid Arthritis.
  Arthritis & rheumatology (Hoboken, N.J.) 2023 Adams C, Nair N, Plant D, Verstappen SMM, Quach HL, Quach DL, Carvidi A, Nititham J, Nakamura M, Graf J, Barton A, Criswell LA, Barcellos LF
• Identification of Sjögren's syndrome patient subgroups by clustering of labial salivary gland DNA methylation profiles.
  PloS one 2023 Chi C, Solomon O, Shiboski C, Taylor KE, Quach H, Quach D, Barcellos LF, Criswell LA
• Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
  Nature communications 2023 Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, …
• Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease.
  Lupus science & medicine 2022 Yavuz S, Pucholt P, Sandling JK, Bianchi M, Leonard D, Bolin K, Imgenberg-Kreuz J, Eloranta ML, Kozyrev SV, Lanata CM, Jönsen A, Bengtsson AA, Sjöwall C, Svenungsson E, Gunnarsson I, Rantapää-…
• Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
  Nature communications 2022 Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, …
• Dynamics of Methylation of CpG Sites Associated With Systemic Lupus Erythematosus Subtypes in a Longitudinal Cohort.
  Arthritis & rheumatology (Hoboken, N.J.) 2022 Lanata CM, Nititham J, Taylor KE, Solomon O, Chung SA, Blazer A, Trupin L, Katz P, Dall'Era M, Yazdany J, Sirota M, Barcellos LF, Criswell LA
• Race, Ethnicity, and Disparities in the Risk of End-Organ Lupus Manifestations Following a Systemic Lupus Erythematosus Diagnosis in a Multiethnic Cohort.
  Arthritis care & research 2022 Aguirre A, Izadi Z, Trupin L, Barbour KE, Greenlund KJ, Katz P, Lanata C, Criswell L, Dall'Era M, Yazdany J
• Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
  Nature communications 2022 Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, …
• A Human MSH6 Germline Variant Associated With Systemic Lupus Erythematosus Induces Lupus-like Disease in Mice.
  ACR open rheumatology 2022 Meas R, Nititham J, Taylor KE, Maher S, Clairmont K, Carufe KEW, Kashgarian M, Nottoli T, Cheong A, Nagel ZD, Gaffney PM, Criswell LA, Sweasy JB
• High Disease Severity Among Asian Patients in a US Multiethnic Cohort of Individuals With Systemic Lupus Erythematosus.
  Arthritis care & research 2022 DeQuattro K, Trupin L, Murphy LB, Rush S, Criswell LA, Lanata CM, Dall'Era M, Katz P, Yazdany J
• Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus.
  Science (New York, N.Y.) 2022 Perez RK, Gordon MG, Subramaniam M, Kim MC, Hartoularos GC, Targ S, Sun Y, Ogorodnikov A, Bueno R, Lu A, Thompson M, Rappoport N, Dahl A, Lanata CM, Matloubian M, Maliskova L, Kwek SS, Li T, Slyper M,…
• P2RY8 variants in lupus patients uncover a role for the receptor in immunological tolerance.
  The Journal of experimental medicine 2021 He Y, Gallman AE, Xie C, Shen Q, Ma J, Wolfreys FD, Sandy M, Arsov T, Wu X, Qin Y, Zhang P, Jiang S, Stanley M, Wu P, Tan J, Ding H, Xue H, Chen W, Xu J, Criswell LA, Nititham J, Adamski M, Kitching …
• Associations Between Smoking and Primary Sjögren Syndrome Classification Using the Sjögren's International Collaborative Clinical Alliance Cohort.
  ACR open rheumatology 2021 Gebreegziabher EA, Oldenburg CE, Shiboski SC, Baer AN, Jordan RC, Rose-Nussbaumer JR, Bunya VY, Akpek EK, Criswell LA, Shiboski CH, Lietman TM, Gonzales JA
• PICS2: next-generation fine mapping via probabilistic identification of causal SNPs.
  Bioinformatics (Oxford, England) 2021 Taylor KE, Ansel KM, Marson A, Criswell LA, Farh KK
• Correction: Hypomethylation mediates genetic association with the major histocompatibility complex genes in Sjögren's syndrome.
  PloS one 2021 Chi C, Taylor KE, Quach H, Quach D, Criswell LA, Barcellos LF
• Variants in BANK1 are associated with lupus nephritis of European ancestry.
  Genes and immunity 2021 Bolin K, Imgenberg-Kreuz J, Leonard D, Sandling JK, Alexsson A, Pucholt P, Haarhaus ML, Almlöf JC, Nititham J, Jönsen A, Sjöwall C, Bengtsson AA, Rantapää-Dahlqvist S, Svenungsson E, Gunnarsson I, …
• Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis.
  Frontiers in immunology 2021 Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M
• Hypomethylation mediates genetic association with the major histocompatibility complex genes in Sjögren's syndrome.
  PloS one 2021 Chi C, Taylor KE, Quach H, Quach D, Criswell LA, Barcellos LF
• Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures.
  Communications biology 2021 Andreoletti G, Lanata CM, Trupin L, Paranjpe I, Jain TS, Nititham J, Taylor KE, Combes AJ, Maliskova L, Ye CJ, Katz P, Dall'Era M, Yazdany J, Criswell LA, Sirota M
• Neuropathic Pain in the Eyes, Body, and Mouth: Insights from the Sjögren's International Collaborative Clinical Alliance.
  Pain practice : the official journal of World Institute of Pain 2021 Gebreegziabher EA, Bunya VY, Baer AN, Jordan RC, Akpek EK, Rose-Nussbaumer J, Criswell LA, Shiboski CH, Lietman TM, Gonzales JA
• Genetic determinants of immune-related adverse events in patients with melanoma receiving immune checkpoint inhibitors.
  Cancer immunology, immunotherapy : CII 2021 Abdel-Wahab N, Diab A, Yu RK, Futreal A, Criswell LA, Tayar JH, Dadu R, Shannon V, Shete SS, Suarez-Almazor ME
• Impact of Limited Health Literacy on Patient-Reported Outcomes in Systemic Lupus Erythematosus.
  Arthritis care & research 2021 Katz P, Dall'Era M, Trupin L, Rush S, Murphy LB, Lanata C, Criswell LA, Yazdany J
• Major Depression and Adverse Patient-Reported Outcomes in Systemic Lupus Erythematosus: Results From a Prospective Longitudinal Cohort.
  Arthritis care & research 2020 Dietz B, Katz P, Dall'Era M, Murphy LB, Lanata C, Trupin L, Criswell LA, Yazdany J
• Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.
  Nature biotechnology 2020 Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ
• The Contribution of Genetics and Epigenetics to Our Understanding of Health Disparities in Rheumatic Diseases.
  Rheumatic diseases clinics of North America 2020 Lanata CM, Blazer A, Criswell LA
• Ocular Clinical Signs and Diagnostic Tests Most Compatible With Keratoconjunctivitis Sicca: A Latent Class Approach.
  Cornea 2020 Gonzales JA, Shiboski SC, Bunya VY, Akpek EK, Rose-Nussbaumer J, Seitzman GD, Criswell LA, Shiboski CH, Lietman TM
• Quality of Care for the Screening, Diagnosis, and Management of Lupus Nephritis Across Multiple Health Care Settings.
  Arthritis care & research 2020 Aggarwal I, Li J, Trupin L, Gaynon L, Katz PP, Lanata C, Criswell L, Murphy LB, Dall'Era M, Yazdany J
• Complement genes contribute sex-biased vulnerability in diverse disorders.
  Nature 2020 Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Boehnke M, …
• Relationships Between Adverse Childhood Experiences and Health Status in Systemic Lupus Erythematosus.
  Arthritis care & research 2020 DeQuattro K, Trupin L, Li J, Katz PP, Murphy LB, Yelin EH, Rush S, Lanata C, Criswell LA, Dall'Era M, Yazdany J
• Author Correction: A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus.
  Nature communications 2020 Lanata CM, Paranjpe I, Nititham J, Taylor KE, Gianfrancesco M, Paranjpe M, Andrews S, Chung SA, Rhead B, Barcellos LF, Trupin L, Katz P, Dall'Era M, Yazdany J, Sirota M, Criswell LA
• HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Gourh P, Safran SA, Alexander T, Boyden SE, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA, Ramos PS, Silver RM, Steen VD, Varga J, Hsu V, Saketkoo LA, Schiopu …
• Psychometric Evaluation of the National Institutes of Health Patient-Reported Outcomes Measurement Information System in a Multiracial, Multiethnic Systemic Lupus Erythematosus Cohort.
  Arthritis care & research 2019 Katz P, Yazdany J, Trupin L, Rush S, Helmick CG, Murphy LB, Lanata C, Criswell LA, Dall'Era M
• Landscape of stimulation-responsive chromatin across diverse human immune cells.
  Nature genetics 2019 Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, Anderson MS, Criswell LA, Greenleaf WJ, …
• A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus.
  Nature communications 2019 Lanata CM, Paranjpe I, Nititham J, Taylor KE, Gianfrancesco M, Paranjpe M, Andrews S, Chung SA, Rhead B, Barcellos LF, Trupin L, Katz P, Dall'Era M, Yazdany J, Sirota M, Criswell LA
• Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology.
  Nature communications 2019 Rahmani E, Schweiger R, Rhead B, Criswell LA, Barcellos LF, Eskin E, Rosset S, Sankararaman S, Halperin E
• Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.
  Annals of the rheumatic diseases 2019 Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de…
• Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers.
  Genes and immunity 2019 Cruz GI, Shao X, Quach H, Quach D, Ho KA, Sterba K, Noble JA, Patsopoulos NA, Busch MP, Triulzi DJ, Ladas N, Blasczyk R, Wong WSW, Solomon BD, Niederhuber JE, Criswell LA, Barcellos LF
• Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
  Human molecular genetics 2018 Hanscombe KB, Morris DL, Noble JA, Dilthey AT, Tombleson P, Kaufman KM, Comeau M, Langefeld CD, Alarcon-Riquelme ME, Gaffney PM, Jacob CO, Sivils KL, Tsao BP, Alarcon GS, Brown EE, Croker J, Edberg J,…
• Increased alloreactive and autoreactive antihuman leucocyte antigen antibodies associated with systemic lupus erythematosus and rheumatoid arthritis.
  Lupus science & medicine 2018 Jackman RP, Cruz GI, Nititham J, Triulzi DJ, Barcellos LF, Criswell LA, Norris PJ, Busch MP
• Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans.
  Arthritis & rheumatology (Hoboken, N.J.) 2018 Gourh P, Remmers EF, Boyden SE, Alexander T, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA, Steen VD, Ramos PS, Silver RM, Korman B, Varga J, Schiopu E, Khanna…
• DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity.
  Lupus science & medicine 2018 Lanata CM, Chung SA, Criswell LA
• Primary Sjögren's Syndrome.
  The New England journal of medicine 2018 Mariette X, Criswell LA
• A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
  Human molecular genetics 2018 Patel ZH, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, …
• Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients.
  PloS one 2018 Lanata CM, Nititham J, Taylor KE, Chung SA, Torgerson DG, Seldin MF, Pons-Estel BA, Tusié-Luna T, Tsao BP, Morand EF, Alarcón-Riquelme ME, Criswell LA
• How Are Ocular Signs and Symptoms of Dry Eye Associated With Depression in Women With and Without Sjögren Syndrome?
  American journal of ophthalmology 2018 Gonzales JA, Chou A, Rose-Nussbaumer JR, Bunya VY, Criswell LA, Shiboski CH, Lietman TM
• Primary Sjögren's Syndrome.
  The New England journal of medicine 2018 Mariette X, Criswell LA
• Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.
  Annals of the rheumatic diseases 2018 Leonard D, Svenungsson E, Dahlqvist J, Alexsson A, Ärlestig L, Taylor KE, Sandling JK, Bengtsson C, Frodlund M, Jönsen A, Eketjäll S, Jensen-Urstad K, Gunnarsson I, Sjöwall C, Bengtsson AA, Eloranta …
• Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients.
  Arthritis & rheumatology (Hoboken, N.J.) 2018 Mok A, Rhead B, Holingue C, Shao X, Quach HL, Quach D, Sinclair E, Graf J, Imboden J, Link T, Harrison R, Chernitskiy V, Barcellos LF, Criswell LA
• Natural History and Predictors of Progression to Sjögren's Syndrome Among Participants of the Sjögren's International Collaborative Clinical Alliance Registry.
  Arthritis care & research 2018 Shiboski CH, Baer AN, Shiboski SC, Lam M, Challacombe S, Lanfranchi HE, Schiødt M, Shirlaw P, Srinivasan M, Umehara H, Vivino FB, Akpek E, Bunya V, Vollenweider CF, Greenspan JS, Daniels TE, Criswell …
• Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.
  Nature biotechnology 2017 Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ
• Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database.
  Medicine 2017 Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA, Steen VD, Varga J, Carns M, Ramos PS, Silver RM, Schiopu E, Khanna D, Hsu V, Gordon JK, Gladue H, Saketkoo LA, Criswell LA, Derk CT, Trojanowski MA…
• Genomewide association study of HLA alloimmunization in previously pregnant blood donors.
  Transfusion 2017 Seielstad M, Page GP, Gaddis N, Lanteri M, Lee TH, Kakaiya R, Barcellos LF, Criswell LA, Triulzi D, Norris PJ, Busch MP, NHLBI REDS-III Study Investigators
• Health-related quality of life and depression among participants in the Sjögren's International Collaborative Clinical Alliance registry.
  RMD open 2017 Chou A, Gonzales JA, Daniels TE, Criswell LA, Shiboski SC, Shiboski CH
• Role of the IL-12/IL-35 balance in patients with Sjögren syndrome.
  The Journal of allergy and clinical immunology 2017 Fogel O, Rivière E, Seror R, Nocturne G, Boudaoud S, Ly B, Gottenberg JE, Le Guern V, Dubost JJ, Nititham J, Taylor KE, Chanson P, Dieudé P, Criswell LA, Jagla B, Thai A, Mingueneau M, Mariette X, …
• Transancestral mapping and genetic load in systemic lupus erythematosus.
  Nature communications 2017 Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V,…
• Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry.
  Arthritis & rheumatology (Hoboken, N.J.) 2017 Taylor KE, Wong Q, Levine DM, McHugh C, Laurie C, Doheny K, Lam MY, Baer AN, Challacombe S, Lanfranchi H, Schiødt M, Srinivasan M, Umehara H, Vivino FB, Zhao Y, Shiboski SC, Daniels TE, Greenspan JS, …
• Reply.
  Arthritis & rheumatology (Hoboken, N.J.) 2017 Vitali C, Scofield H, Shiboski SC, Criswell LA, Lietman TM, Seror R, Labetoulle M, Mariette X, Rasmussen A, Bowman SJ, Shiboski CH
• Increased risk of rheumatoid arthritis among mothers with children who carry DRB1 risk-associated alleles.
  Annals of the rheumatic diseases 2017 Cruz GI, Shao X, Quach H, Ho KA, Sterba K, Noble JA, Patsopoulos NA, Busch MP, Triulzi DJ, Wong WS, Solomon BD, Niederhuber JE, Criswell LA, Barcellos LF
• Alterations in the Salivary Proteome and N-Glycome of Sjögren's Syndrome Patients.
  Journal of proteome research 2017 Hall SC, Hassis ME, Williams KE, Albertolle ME, Prakobphol A, Dykstra AB, Laurance M, Ona K, Niles RK, Prasad N, Gormley M, Shiboski C, Criswell LA, Witkowska HE, Fisher SJ
• Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes.
  Arthritis & rheumatology (Hoboken, N.J.) 2017 Rhead B, Holingue C, Cole M, Shao X, Quach HL, Quach D, Shah K, Sinclair E, Graf J, Link T, Harrison R, Rahmani E, Halperin E, Wang W, Firestein GS, Barcellos LF, Criswell LA
• Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses.
  Lupus science & medicine 2016 Mok A, Solomon O, Nayak RR, Coit P, Quach HL, Nititham J, Sawalha AH, Barcellos LF, Criswell LA, Chung SA
• Epigenetic Signatures of Salivary Gland Inflammation in Sjögren's Syndrome.
  Arthritis & rheumatology (Hoboken, N.J.) 2016 Cole MB, Quach H, Quach D, Baker A, Taylor KE, Barcellos LF, Criswell LA
• 2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts.
  Arthritis & rheumatology (Hoboken, N.J.) 2016 Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X, International Sjögren's Syndrome Criteria Working Group
• 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: A consensus and data-driven methodology involving three international patient cohorts.
  Annals of the rheumatic diseases 2016 Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X, International Sjögren's Syndrome Criteria Working Group
• Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
  Nature communications 2016 Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, …
• Association of Dry Eye Tests With Extraocular Signs Among 3514 Participants in the Sjögren's Syndrome International Registry.
  American journal of ophthalmology 2016 Bunya VY, Bhosai SJ, Heidenreich AM, Kitagawa K, Larkin GB, Lietman TM, Gaynor BD, Akpek EK, Massaro-Giordano M, Srinivasan M, Porco TC, Whitcher JP, Shiboski SC, Criswell LA, Shiboski CH, Sjögren's …
• Brief Report: Whole-Exome Sequencing for Identification of Potential Causal Variants for Diffuse Cutaneous Systemic Sclerosis.
  Arthritis & rheumatology (Hoboken, N.J.) 2016 Mak AC, Tang PL, Cleveland C, Smith MH, Kari Connolly M, Katsumoto TR, Wolters PJ, Kwok PY, Criswell LA
• Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
  Nature communications 2016 Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, …
• A Child's HLA-DRB1 genotype increases maternal risk of systemic lupus erythematosus.
  Journal of autoimmunity 2016 Cruz GI, Shao X, Quach H, Ho KA, Sterba K, Noble JA, Patsopoulos NA, Busch MP, Triulzi DJ, Wong WS, Solomon BD, Niederhuber JE, Criswell LA, Barcellos LF
• Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
  Arthritis & rheumatology (Hoboken, N.J.) 2016 Lessard CJ, Sajuthi S, Zhao J, Kim K, Ice JA, Li H, Ainsworth H, Rasmussen A, Kelly JA, Marion M, Bang SY, Joo YB, Choi J, Lee HS, Kang YM, Suh CH, Chung WT, Lee SK, Choe JY, Shim SC, Oh JH, Kim YJ, …
• Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
  Arthritis & rheumatology (Hoboken, N.J.) 2016 Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez EM, Cucho-…
• Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
  Annals of the rheumatic diseases 2016 Deng Y, Zhao J, Sakurai D, Sestak AL, Osadchiy V, Langefeld CD, Kaufman KM, Kelly JA, James JA, Petri MA, Bae SC, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Criswell LA, Freedman BI, Kamen DL, …
• Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins.
  Journal of autoimmunity 2016 Elboudwarej E, Cole M, Briggs FB, Fouts A, Fain PR, Quach H, Quach D, Sinclair E, Criswell LA, Lane JA, Steck AK, Barcellos LF, Noble JA
• Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
  Clinical immunology (Orlando, Fla.) 2015 Zhao J, Wu H, Langefeld CD, Kaufman KM, Kelly JA, Bae SC, Marta E. Alarcón-Riquelme for the BIOLUPUS and GENLES networks, Alarcón GS, Anaya JM, Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob …
• Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma.
  Annals of the rheumatic diseases 2015 Nocturne G, Tarn J, Boudaoud S, Locke J, Miceli-Richard C, Hachulla E, Dubost JJ, Bowman S, Gottenberg JE, Criswell LA, Lessard CJ, Sivils KL, Carapito R, Bahram S, Seror R, Ng WF, Mariette X
• Molecular Subsetting of Interferon Pathways in Sjögren's Syndrome.
  Arthritis & rheumatology (Hoboken, N.J.) 2015 Hall JC, Baer AN, Shah AA, Criswell LA, Shiboski CH, Rosen A, Casciola-Rosen L
• Increase in Dickkopf-1 Serum Level in Recent Spondyloarthritis. Data from the DESIR Cohort.
  PloS one 2015 Nocturne G, Pavy S, Boudaoud S, Seror R, Goupille P, Chanson P, van der Heijde D, van Gaalen F, Berenbaum F, Mariette X, Briot K, Feydy A, Claudepierre P, Dieudé P, Nithitham J, Taylor KE, Criswell LA…
• Genome-Wide Assessment of Differential DNA Methylation Associated with Autoantibody Production in Systemic Lupus Erythematosus.
  PloS one 2015 Chung SA, Nititham J, Elboudwarej E, Quach HL, Taylor KE, Barcellos LF, Criswell LA
• Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
  American journal of human genetics 2015 Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, …
• Genetic contribution of DKK-1 polymorphisms to RA structural severity and DKK-1 level of expression.
  Annals of the rheumatic diseases 2015 Miceli-Richard C, Taylor KE, Nititham J, Seror R, Nocturne G, Boudaoud S, Dieude P, Constantin A, Devauchelle-Pensec V, Tobón GJ, Mariette X, Criswell LA
• The SSB-positive/SSA-negative antibody profile is not associated with key phenotypic features of Sjögren's syndrome.
  Annals of the rheumatic diseases 2015 Baer AN, McAdams DeMarco M, Shiboski SC, Lam MY, Challacombe S, Daniels TE, Dong Y, Greenspan JS, Kirkham BW, Lanfranchi HE, Schiødt M, Srinivasan M, Umehara H, Vivino FB, Vollenweider CF, Zhao Y, …
• Interactions between patients, providers, and health systems and technical quality of care.
  Arthritis care & research 2015 Yelin E, Yazdany J, Tonner C, Trupin L, Criswell LA, Katz P, Schmajuk G
• Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.
  Current rheumatology reports 2015 Korman BD, Criswell LA
• Lupus risk variants in the PXK locus alter B-cell receptor internalization.
  Frontiers in genetics 2015 Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, …
• The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
  Human molecular genetics 2014 Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos …
• Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
  Annals of the rheumatic diseases 2014 Zhao J, Giles BM, Taylor RL, Yette GA, Lough KM, Ng HL, Abraham LJ, Wu H, Kelly JA, Glenn SB, Adler AJ, Williams AH, Comeau ME, Ziegler JT, Marion M, Alarcón-Riquelme ME, BIOLUPUS and GENLES Networks,…
• A polymorphism in TLR2 is associated with arterial thrombosis in a multiethnic population of patients with systemic lupus erythematosus.
  Arthritis & rheumatology (Hoboken, N.J.) 2014 Kaiser R, Tang LF, Taylor KE, Sterba K, Nititham J, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri M, Rauch J, Miller E, Mesznik K, Kwok PY, Kimberly RP, …
• Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
  Journal of the American Society of Nephrology : JASN 2014 Chung SA, Brown EE, Williams AH, Ramos PS, Berthier CC, Bhangale T, Alarcon-Riquelme ME, Behrens TW, Criswell LA, Graham DC, Demirci FY, Edberg JC, Gaffney PM, Harley JB, Jacob CO, Kamboh MI, Kelly JA…
• Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
  American journal of human genetics 2014 Guthridge JM, Lu R, Sun H, Sun C, Wiley GB, Dominguez N, Macwana SR, Lessard CJ, Kim-Howard X, Cobb BL, Kaufman KM, Kelly JA, Langefeld CD, Adler AJ, Harley IT, Merrill JT, Gilkeson GS, Kamen DL, …
• Genetic, genomic and epigenetic studies as tools for elucidating disease pathogenesis in primary Sjögren's syndrome.
  Expert review of clinical immunology 2014 Miceli-Richard C, Criswell LA
• End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.
  Arthritis & rheumatology (Hoboken, N.J.) 2014 Freedman BI, Langefeld CD, Andringa KK, Croker JA, Williams AH, Garner NE, Birmingham DJ, Hebert LA, Hicks PJ, Segal MS, Edberg JC, Brown EE, Alarcón GS, Costenbader KH, Comeau ME, Criswell LA, Harley…
• Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome.
  Journal of autoimmunity 2014 Gong YZ, Nititham J, Taylor K, Miceli-Richard C, Sordet C, Wachsmann D, Bahram S, Georgel P, Criswell LA, Sibilia J, Mariette X, Alsaleh G, Gottenberg JE
• Genetics of rheumatoid arthritis contributes to biology and drug discovery.
  Nature 2013 Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas…
• Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.
  Blood 2013 Nocturne G, Boudaoud S, Miceli-Richard C, Viengchareun S, Lazure T, Nititham J, Taylor KE, Ma A, Busato F, Melki J, Lessard CJ, Sivils KL, Dubost JJ, Hachulla E, Gottenberg JE, Lombès M, Tost J, …
• Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
  PLoS genetics 2013 Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc?n-Riquelme ME, BIOLUPUS and GENLES networks, Edberg JC, Kimberly RP, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón …
• Non-lymphoma hematological malignancies in systemic lupus erythematosus.
  Oncology 2013 Lu M, Bernatsky S, Ramsey-Goldman R, Petri M, Manzi S, Urowitz MB, Gladman D, Fortin PR, Ginzler EM, Yelin E, Bae SC, Wallace DJ, Jacobsen S, Dooley MA, Peschken CA, Alarcón GS, Nived O, Gottesman L, …
• ABIN1 dysfunction as a genetic basis for lupus nephritis.
  Journal of the American Society of Nephrology : JASN 2013 Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney…
• PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
  PloS one 2013 Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, …
• NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome.
  Science translational medicine 2013 Rusakiewicz S, Nocturne G, Lazure T, Semeraro M, Flament C, Caillat-Zucman S, Sène D, Delahaye N, Vivier E, Chaba K, Poirier-Colame V, Nordmark G, Eloranta ML, Eriksson P, Theander E, Forsblad-d'Elia …
• Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
  PLoS genetics 2013 Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell LA, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, …
• Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
  The Journal of rheumatology 2013 Ramos PS, Oates JC, Kamen DL, Williams AH, Gaffney PM, Kelly JA, Kaufman KM, Kimberly RP, Niewold TB, Jacob CO, Tsao BP, Alarcón GS, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá …
• TDP-43 frontotemporal lobar degeneration and autoimmune disease.
  Journal of neurology, neurosurgery, and psychiatry 2013 Miller ZA, Rankin KP, Graff-Radford NR, Takada LT, Sturm VE, Cleveland CM, Criswell LA, Jaeger PA, Stan T, Heggeli KA, Hsu SC, Karydas A, Khan BK, Grinberg LT, Gorno-Tempini ML, Boxer AL, Rosen HJ, …
• Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.
  PLoS genetics 2013 Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, …
• MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
  PLoS genetics 2013 Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse …
• Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
  PLoS genetics 2013 Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarcón GS, Edberg JC, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, …
• Cancer risk in systemic lupus: an updated international multi-centre cohort study.
  Journal of autoimmunity 2013 Bernatsky S, Ramsey-Goldman R, Labrecque J, Joseph L, Boivin JF, Petri M, Zoma A, Manzi S, Urowitz MB, Gladman D, Fortin PR, Ginzler E, Yelin E, Bae SC, Wallace DJ, Edworthy S, Jacobsen S, Gordon C, …
• Lymphoma risk in systemic lupus: effects of disease activity versus treatment.
  Annals of the rheumatic diseases 2013 Bernatsky S, Ramsey-Goldman R, Joseph L, Boivin JF, Costenbader KH, Urowitz MB, Gladman DD, Fortin PR, Nived O, Petri MA, Jacobsen S, Manzi S, Ginzler EM, Isenberg D, Rahman A, Gordon C, Ruiz-…
• Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.
  Arthritis and rheumatism 2013 Kaiser R, Taylor KE, Deng Y, Zhao J, Li Y, Nititham J, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vila LM, Petri M, Kimberly RP, Feng X…
• Sex differences in assessment of obesity in rheumatoid arthritis.
  Arthritis care & research 2013 Katz PP, Yazdany J, Trupin L, Schmajuk G, Margaretten M, Barton J, Criswell LA, Yelin EH
• Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
  European journal of human genetics : EJHG 2012 Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, Julkunen…
• Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis.
  Annals of the rheumatic diseases 2012 Umicevic Mirkov M, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, Makkinje RR, Lee AT, Huizinga TW, Allaart R, Barton A, Mariette X, Miceli CR, Criswell LA, Tak PP, de Vries N, Saevarsdottir S, Padyukov L,…
• Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
  Arthritis and rheumatism 2012 Adrianto I, Wang S, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME, BIOLUPUS and…
• Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
  Arthritis and rheumatism 2012 Sánchez E, Rasmussen A, Riba L, Acevedo-Vasquez E, Kelly JA, Langefeld CD, Williams AH, Ziegler JT, Comeau ME, Marion MC, García-De La Torre I, Maradiaga-Ceceña MA, Cardiel MH, Esquivel-Valerio JA, …
• Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
  American journal of human genetics 2012 Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, International…
• CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation.
  Nature genetics 2012 Manjarrez-Orduño N, Marasco E, Chung SA, Katz MS, Kiridly JF, Simpfendorfer KR, Freudenberg J, Ballard DH, Nashi E, Hopkins TJ, Cunninghame Graham DS, Lee AT, Coenen MJ, Franke B, Swinkels DW, Graham …
• European genetic ancestry is associated with a decreased risk of lupus nephritis.
  Arthritis and rheumatism 2012 Richman IB, Taylor KE, Chung SA, Trupin L, Petri M, Yelin E, Graham RR, Lee A, Behrens TW, Gregersen PK, Seldin MF, Criswell LA
• Cardiovascular disease and cognitive dysfunction in systemic lupus erythematosus.
  Arthritis care & research 2012 Murray SG, Yazdany J, Kaiser R, Criswell LA, Trupin L, Yelin EH, Katz PP, Julian LJ
• Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
  Annals of the rheumatic diseases 2012 Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, Comeau ME, Marion MC, Glenn SB, Cantor RM, Grossman JM, Hahn BH, Song YW, Yu CY, James JA,…
• Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus.
  Arthritis research & therapy 2012 Sacre K, Criswell LA, McCune JM
• Genetic risk factors for thrombosis in systemic lupus erythematosus.
  The Journal of rheumatology 2012 Kaiser R, Li Y, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri MA, Kimberly RP, Taylor KE, Criswell LA
• Quality of care in systemic lupus erythematosus: application of quality measures to understand gaps in care.
  Journal of general internal medicine 2012 Yazdany J, Trupin L, Tonner C, Dudley RA, Zell J, Panopalis P, Schmajuk G, Julian L, Katz P, Criswell LA, Yelin E
• Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
  Annals of the rheumatic diseases 2012 Kim K, Brown EE, Choi CB, Alarcón-Riquelme ME, BIOLUPUS, Kelly JA, Glenn SB, Ojwang JO, Adler A, Lee HS, Boackle SA, Criswell LA, Alarcón GS, Edberg JC, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, …
• Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus.
  Arthritis care & research 2012 Katz P, Julian L, Tonner MC, Yazdany J, Trupin L, Yelin E, Criswell LA
• Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
  American journal of human genetics 2012 Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ, Alarcón…
• Validity of brief screening tools for cognitive impairment in rheumatoid arthritis and systemic lupus erythematosus.
  Arthritis care & research 2012 Julian LJ, Yazdany J, Trupin L, Criswell LA, Yelin E, Katz PP
• Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
  Arthritis and rheumatism 2012 Hughes T, Adler A, Kelly JA, Kaufman KM, Williams AH, Langefeld CD, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Boackle SA, Stevens AM, Reveille JD, Sanchez E, Martín J, …
• Longitudinal study of the impact of incident organ manifestations and increased disease activity on work loss among persons with systemic lupus erythematosus.
  Arthritis care & research 2012 Yelin E, Tonner C, Trupin L, Gansky SA, Julian L, Katz P, Yazdany J, Kaiser R, Criswell LA
• Emerging patterns of genetic overlap across autoimmune disorders.
  Genome medicine 2012 Richard-Miceli C, Criswell LA
• Primary Sjögren's syndrome as a systemic disease: a study of participants enrolled in an international Sjögren's syndrome registry.
  Arthritis care & research 2012 Malladi AS, Sack KE, Shiboski SC, Shiboski CH, Baer AN, Banushree R, Dong Y, Helin P, Kirkham BW, Li M, Sugai S, Umehara H, Vivino FB, Vollenweider CF, Zhang W, Zhao Y, Greenspan JS, Daniels TE, …
• Evaluation of TRAF6 in a large multiancestral lupus cohort.
  Arthritis and rheumatism 2012 Namjou B, Choi CB, Harley IT, Alarcón-Riquelme ME, BIOLUPUS Network, Kelly JA, Glenn SB, Ojwang JO, Adler A, Kim K, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown EE, Edberg J, Alarcón GS, …
• A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
  PLoS genetics 2011 Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcón-Riquelme ME,…
• Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
  Annals of the rheumatic diseases 2011 Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarcón GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, …
• Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.
  PLoS genetics 2011 Cunninghame Graham DS, Morris DL, Bhangale TR, Criswell LA, Syvänen AC, Rönnblom L, Behrens TW, Graham RR, Vyse TJ
• Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.
  Nature immunology 2011 Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, DeFranco A, Criswell LA, Nakamura MC, Ma A
• Impact of obesity on functioning among women with systemic lupus erythematosus.
  Arthritis care & research 2011 Katz P, Yazdany J, Julian L, Trupin L, Margaretten M, Yelin E, Criswell LA
• Recommendations for publication of genetic association studies in Arthritis & Rheumatism.
  Arthritis and rheumatism 2011 Plenge RM, Bridges SL, Huizinga TW, Criswell LA, Gregersen PK
• Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
  Arthritis and rheumatism 2011 Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Bae SC, Lee JH, Lee JS, Chang DM, Song YW, Yu CY, Kimberly RP, Edberg JC, Brown EE…
• Brief index of lupus damage: a patient-reported measure of damage in systemic lupus erythematosus.
  Arthritis care & research 2011 Yazdany J, Trupin L, Gansky SA, Dall'era M, Yelin EH, Criswell LA, Katz PP
• Associations between salivary gland histopathologic diagnoses and phenotypic features of Sjögren's syndrome among 1,726 registry participants.
  Arthritis and rheumatism 2011 Daniels TE, Cox D, Shiboski CH, Schiødt M, Wu A, Lanfranchi H, Umehara H, Zhao Y, Challacombe S, Lam MY, De Souza Y, Schiødt J, Holm H, Bisio PA, Gandolfo MS, Sawaki T, Li M, Zhang W, Varghese-Jacob B…
• Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
  Arthritis and rheumatism 2011 Ramos PS, Williams AH, Ziegler JT, Comeau ME, Guy RT, Lessard CJ, Li H, Edberg JC, Zidovetzki R, Criswell LA, Gaffney PM, Graham DC, Graham RR, Kelly JA, Kaufman KM, Brown EE, Alarcón GS, Petri MA, …
• Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
  Annals of the rheumatic diseases 2011 Sanchez E, Nadig A, Richardson BC, Freedman BI, Kaufman KM, Kelly JA, Niewold TB, Kamen DL, Gilkeson GS, Ziegler JT, Langefeld CD, Alarcón GS, Edberg JC, Ramsey-Goldman R, Petri M, Brown EE, Kimberly …
• Using the Center for Epidemiologic Studies Depression Scale to screen for depression in systemic lupus erythematosus.
  Arthritis care & research 2011 Julian LJ, Gregorich SE, Tonner C, Yazdany J, Trupin L, Criswell LA, Yelin E, Katz PP
• Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
  PLoS genetics 2011 Zhao J, Wu H, Khosravi M, Cui H, Qian X, Kelly JA, Kaufman KM, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Adler A, Glenn SB, Alarcón-Riquelme ME, BIOLUPUS Network, GENLES Network, …
• Cardiovascular and disease-related predictors of depression in systemic lupus erythematosus.
  Arthritis care & research 2011 Julian LJ, Tonner C, Yelin E, Yazdany J, Trupin L, Criswell LA, Katz PP
• Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
  PLoS genetics 2011 Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, Jacob CO, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, SLEGEN, Petri M, Demirci FY, Kamboh MI, Manzi S, Gregersen PK, …
• Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
  Nature genetics 2011 Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME, BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Bang SY, Boackle …
• Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.
  PLoS genetics 2011 Taylor KE, Chung SA, Graham RR, Ortmann WA, Lee AT, Langefeld CD, Jacob CO, Kamboh MI, Alarcón-Riquelme ME, Tsao BP, Moser KL, Gaffney PM, Harley JB, Petri M, Manzi S, Gregersen PK, Behrens TW, …
• Obesity and its measurement in a community-based sample of women with systemic lupus erythematosus.
  Arthritis care & research 2011 Katz P, Gregorich S, Yazdany J, Trupin L, Julian L, Yelin E, Criswell LA
• Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
  American journal of human genetics 2010 Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, Williams AH, Gallant CJ, Marta E. Alarcón-Riquelme on behalf of the BIOLUPUS and GENLES Networks, Anaya JM, Bae SC, Boackle SA, …
• A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.
  European journal of human genetics : EJHG 2010 Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Mälarstig A, …
• Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study.
  Arthritis research & therapy 2010 Mikuls TR, Gould KA, Bynoté KK, Yu F, Levan TD, Thiele GM, Michaud KD, O'Dell JR, Reimold AM, Hooker R, Caplan L, Johnson DS, Kerr G, Richards JS, Cannon GW, Criswell LA, Noble JA, Bridges SL, Hughes …
• Childhood-onset disease as a predictor of mortality in an adult cohort of patients with systemic lupus erythematosus.
  Arthritis care & research 2010 Hersh AO, Trupin L, Yazdany J, Panopalis P, Julian L, Katz P, Criswell LA, Yelin E
• Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
  Arthritis and rheumatism 2010 Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB…
• Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.
  Arthritis and rheumatism 2010 Bronson PG, Komorowski LK, Ramsay PP, May SL, Noble J, Lane JA, Thomson G, Claas FH, Seldin MF, Kelly JA, Harley JB, Moser KL, Gaffney PM, Behrens T, Criswell LA, Barcellos LF
• Role of community and individual characteristics in physician visits for persons with systemic lupus erythematosus.
  Arthritis care & research 2010 Tonner C, Trupin L, Yazdany J, Criswell L, Katz P, Yelin E
• Provision of preventive health care in systemic lupus erythematosus: data from a large observational cohort study.
  Arthritis research & therapy 2010 Yazdany J, Tonner C, Trupin L, Panopalis P, Gillis JZ, Hersh AO, Julian LJ, Katz PP, Criswell LA, Yelin EH
• Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
  Nature genetics 2010 Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG, BIRAC Consortium, Barton A, Bowes J, …
• Recent advances in the genetics of systemic lupus erythematosus.
  Expert review of clinical immunology 2010 Flesher DL, Sun X, Behrens TW, Graham RR, Criswell LA
• Frequent use of the emergency department among persons with systemic lupus erythematosus.
  Arthritis care & research 2010 Panopalis P, Gillis JZ, Yazdany J, Trupin L, Hersh A, Julian L, Criswell LA, Katz P, Yelin E
• Genetics research in systemic lupus erythematosus for clinicians: methodology, progress, and controversies.
  Current opinion in rheumatology 2010 Kaiser R, Criswell LA
• Gene discovery in rheumatoid arthritis highlights the CD40/NF-kappaB signaling pathway in disease pathogenesis.
  Immunological reviews 2010 Criswell LA
• Conditional analysis of the major histocompatibility complex in rheumatoid arthritis.
  BMC proceedings 2009 Taylor KE, Criswell LA
• Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data.
  BMC proceedings 2009 Amos CI, Chen WV, Seldin MF, Remmers EF, Taylor KE, Criswell LA, Lee AT, Plenge RM, Kastner DL, Gregersen PK
• Tumour necrosis factor alpha -308G->A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis.
  Annals of the rheumatic diseases 2009 Pavy S, Toonen EJ, Miceli-Richard C, Barrera P, van Riel PL, Criswell LA, Mariette X, Coenen MJ
• Systematic review and metaanalysis of patient self-report versus trained assessor joint counts in rheumatoid arthritis.
  The Journal of rheumatology 2009 Barton JL, Criswell LA, Kaiser R, Chen YH, Schillinger D
• Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.
  Nature genetics 2009 Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG, BIRAC Consortium, Barton A, Bowes J, Burtt NP, Chang M, …
• High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
  PLoS genetics 2009 Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
• A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
  Nature genetics 2009 Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Rantapää-Dahlqvist S…
• European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus.
  Arthritis and rheumatism 2009 Chung SA, Tian C, Taylor KE, Lee AT, Ortmann WA, Hom G, Graham RR, Nititham J, Kelly JA, Morrisey J, Wu H, Yin H, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, Manzi S, Petri M, …
• Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus.
  Arthritis and rheumatism 2009 Bachen EA, Chesney MA, Criswell LA
• REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
  Nature genetics 2009 Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Plenge RM, Holers VM, Mikuls TR, Sokka T, Moreland LW, Bridges SL, Xie G, Begovich AB, Siminovitch KA
• An early view of the international Sjögren's syndrome registry.
  Arthritis and rheumatism 2009 Daniels TE, Criswell LA, Shiboski C, Shiboski S, Lanfranchi H, Dong Y, Schiødt M, Umehara H, Sugai S, Challacombe S, Greenspan JS, Sjögren's International Collaborative Clinical Alliance Research …
• Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.
  The Journal of clinical investigation 2009 Liu K, Li QZ, Delgado-Vega AM, Abelson AK, Sánchez E, Kelly JA, Li L, Liu Y, Zhou J, Yan M, Ye Q, Liu S, Xie C, Zhou XJ, Chung SA, Pons-Estel B, Witte T, de Ramón E, Bae SC, Barizzone N, Sebastiani GD…
• Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.
  Molecular medicine (Cambridge, Mass.) 2009 Cui J, Taylor KE, Destefano AL, Criswell LA, Izmailova ES, Parker A, Roubenoff R, Plenge RM, Weinblatt ME, Shadick NA, Karlson EW
• Depression, medication adherence, and service utilization in systemic lupus erythematosus.
  Arthritis and rheumatism 2009 Julian LJ, Yelin E, Yazdany J, Panopalis P, Trupin L, Criswell LA, Katz P
• Work loss and work entry among persons with systemic lupus erythematosus: comparisons with a national matched sample.
  Arthritis and rheumatism 2009 Yelin E, Tonner C, Trupin L, Panopalis P, Yazdany J, Julian L, Katz P, Criswell LA
• Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus.
  Arthritis and rheumatism 2009 Hersh AO, von Scheven E, Yazdany J, Panopalis P, Trupin L, Julian L, Katz P, Criswell LA, Yelin E
• The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series.
  Arthritis and rheumatism 2009 Korman BD, Seldin MF, Taylor KE, Le JM, Lee AT, Plenge RM, Amos CI, Criswell LA, Gregersen PK, Kastner DL, Remmers EF
• Health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosus.
  Arthritis and rheumatism 2008 Panopalis P, Yazdany J, Gillis JZ, Julian L, Trupin L, Hersh AO, Criswell LA, Katz P, Yelin E
• Common variants at CD40 and other loci confer risk of rheumatoid arthritis.
  Nature genetics 2008 Raychaudhuri S, Remmers EF, Lee AT, Hackett R, Guiducci C, Burtt NP, Gianniny L, Korman BD, Padyukov L, Kurreeman FA, Chang M, Catanese JJ, Ding B, Wong S, van der Helm-van Mil AH, Neale BM, Coblyn J,…
• Meta-analysis of genome-wide linkage studies across autoimmune diseases.
  European journal of human genetics : EJHG 2008 Forabosco P, Bouzigon E, Ng MY, Hermanowski J, Fisher SA, Criswell LA, Lewis CM
• Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus.
  Nature genetics 2008 Musone SL, Taylor KE, Lu TT, Nititham J, Ferreira RC, Ortmann W, Shifrin N, Petri MA, Kamboh MI, Manzi S, Seldin MF, Gregersen PK, Behrens TW, Ma A, Kwok PY, Criswell LA
• The role of neighborhood and individual socioeconomic status in outcomes of systemic lupus erythematosus.
  The Journal of rheumatology 2008 Trupin L, Tonner MC, Yazdany J, Julian LJ, Criswell LA, Katz PP, Yelin E
• A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.
  PLoS genetics 2008 Chang M, Rowland CM, Garcia VE, Schrodi SJ, Catanese JJ, van der Helm-van Mil AH, Ardlie KG, Amos CI, Criswell LA, Kastner DL, Gregersen PK, Kurreeman FA, Toes RE, Huizinga TW, Seldin MF, Begovich AB
• The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis.
  Arthritis and rheumatism 2008 Chang M, Saiki RK, Cantanese JJ, Lew D, van der Helm-van Mil AH, Toes RE, Huizinga TW, Ardlie KG, Criswell LA, Seldin MF, Amos CI, Kastner DL, Gregersen PK, Schrodi SJ, Begovich AB
• Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.
  PLoS genetics 2008 Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, Seldin MF, Gregersen PK, Behrens TW, Criswell LA
• Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus.
  Molecular medicine (Cambridge, Mass.) 2008 Lee HS, Lee AT, Criswell LA, Seldin MF, Amos CI, Carulli JP, Navarrete C, Remmers EF, Kastner DL, Plenge RM, Li W, Gregersen PK
• Genetic variants that predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis: current challenges and future directions.
  Current opinion in rheumatology 2008 Plenge RM, Criswell LA
• Admixed populations and autoimmunity.
  Arthritis and rheumatism 2008 Criswell LA, Seldin MF
• Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
  The New England journal of medicine 2008 Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapää-…
• Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
  Nature genetics 2008 International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcón-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, …
• The genetic contribution to systemic lupus erythematosus.
  Bulletin of the NYU hospital for joint diseases 2008 Criswell LA
• Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits.
  BMC proceedings 2007 Amos CI, Chen WV, Remmers E, Siminovitch KA, Seldin MF, Criswell LA, Lee AT, John S, Shephard ND, Worthington J, Cornelis F, Plenge RM, Begovich AB, Dyer TD, Kastner DL, Gregersen PK
• Genome-wide single-nucleotide polymorphism linkage analyses of quantitative rheumatoid arthritis phenotypes in Caucasian NARAC families.
  BMC proceedings 2007 Taylor KE, Chen W, Amos CI, Criswell LA
• Impact of memory impairment on employment status in persons with systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Panopalis P, Julian L, Yazdany J, Gillis JZ, Trupin L, Hersh A, Criswell LA, Katz P, Yelin E
• PTPN22: its role in SLE and autoimmunity.
  Autoimmunity 2007 Chung SA, Criswell LA
• STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus.
  The New England journal of medicine 2007 Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, de Bakker PI, Le JM, Lee HS, Batliwalla F, Li W, Masters SL, Booty MG, Carulli JP, Padyukov L, Alfredsson L, Klareskog L, Chen WV, Amos CI,…
• TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
  The New England journal of medicine 2007 Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, …
• Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Kinder BW, Freemer MM, King TE, Lum RF, Nititham J, Taylor K, Edberg JC, Bridges SL, Criswell LA
• Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts.
  Arthritis and rheumatism 2007 Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, Wolfe F, Lum RF, Massarotti E, Weisman M, Bombardier C, Karlson EW, Criswell LA, Vlietinck R, Gregersen PK
• Association of socioeconomic and demographic factors with utilization of rheumatology subspecialty care in systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Yazdany J, Gillis JZ, Trupin L, Katz P, Panopalis P, Criswell LA, Yelin E
• Medicaid and access to care among persons with systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Gillis JZ, Yazdany J, Trupin L, Julian L, Panopalis P, Criswell LA, Katz P, Yelin E
• Impact of health maintenance organizations and fee-for-service on health care utilization among people with systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Yelin E, Trupin L, Katz P, Criswell LA, Yazdany J, Gillis J, Panopalis P
• Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
  Proceedings of the National Academy of Sciences of the United States of America 2007 Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, …
• Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.
  European journal of human genetics : EJHG 2007 Graham RR, Ortmann W, Rodine P, Espe K, Langefeld C, Lange E, Williams A, Beck S, Kyogoku C, Moser K, Gaffney P, Gregersen PK, Criswell LA, Harley JB, Behrens TW
• Work dynamics among persons with systemic lupus erythematosus.
  Arthritis and rheumatism 2007 Yelin E, Trupin L, Katz P, Criswell L, Yazdany J, Gillis J, Panopalis P
• Dissecting the heterogeneity of rheumatoid arthritis through linkage analysis of quantitative traits.
  Arthritis and rheumatism 2007 Criswell LA, Chen WV, Jawaheer D, Lum RF, Wener MH, Gu X, Gregersen PK, Amos CI
• Influence of male sex on disease phenotype in familial rheumatoid arthritis.
  Arthritis and rheumatism 2006 Jawaheer D, Lum RF, Gregersen PK, Criswell LA
• Recent advances in the genetics of rheumatoid arthritis.
  Current rheumatology reports 2006 Deighton C, Criswell LA
• Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile.
  The Journal of rheumatology 2006 Janssens AC, Steyerberg EW, Jiang Y, Habbema JD, Van Duijn CM, Criswell LA
• Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women.
  Annals of the rheumatic diseases 2006 Criswell LA, Saag KG, Mikuls TR, Cerhan JR, Merlino LA, Lum RF, Pfeiffer KA, Woehl B, Seldin MF
• The functional -169T-->C single-nucleotide polymorphism in FCRL3 is not associated with rheumatoid arthritis in white North Americans.
  Arthritis and rheumatism 2006 Hu X, Chang M, Saiki RK, Cargill MA, Begovich AB, Ardlie KG, Criswell LA, Seldin MF, Amos CI, Gregersen PK, Kastner DL, Remmers EF
• Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.
  Arthritis and rheumatism 2005 Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, Lum RF, Massarotti E, Weisman M, Bombardier C, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Gregersen PK
• Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins.
  Arthritis and rheumatism 2005 Huizinga TW, Amos CI, van der Helm-van Mil AH, Chen W, van Gaalen FA, Jawaheer D, Schreuder GM, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RR, Gregersen PK, Toes RE, Criswell LA
• Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for clinical epidemiology and forensic medicine.
  Human genetics 2005 Yang N, Li H, Criswell LA, Gregersen PK, Alarcon-Riquelme ME, Kittles R, Shigeta R, Silva G, Patel PI, Belmont JW, Seldin MF
• PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis.
  American journal of human genetics 2005 Carlton VE, Hu X, Chokkalingam AP, Schrodi SJ, Brandon R, Alexander HC, Chang M, Catanese JJ, Leong DU, Ardlie KG, Kastner DL, Seldin MF, Criswell LA, Gregersen PK, Beasley E, Thomson G, Amos CI, …
• Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.
  American journal of human genetics 2005 Criswell LA, Pfeiffer KA, Lum RF, Gonzales B, Novitzke J, Kern M, Moser KL, Begovich AB, Carlton VE, Li W, Lee AT, Ortmann W, Behrens TW, Gregersen PK
• Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis.
  Arthritis and rheumatism 2004 Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell LA
• The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept.
  Arthritis and rheumatism 2004 Criswell LA, Lum RF, Turner KN, Woehl B, Zhu Y, Wang J, Tiwari HK, Edberg JC, Kimberly RP, Moreland LW, Seldin MF, Bridges SL
• A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.
  American journal of human genetics 2004 Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, Ardlie KG, Huang Q, Smith AM, Spoerke JM, Conn MT, Chang M, Chang SY, Saiki RK, Catanese JJ, Leong DU, Garcia VE, …
• Familial clustering of disease features: implications for the etiology and investigation of systemic autoimmune disease.
  Arthritis and rheumatism 2004 Criswell LA
• Putative ancestral origins of chromosomal segments in individual african americans: implications for admixture mapping.
  Genome research 2004 Seldin MF, Morii T, Collins-Schramm HE, Chima B, Kittles R, Criswell LA, Li H
• Clustering of disease features within 512 multicase rheumatoid arthritis families.
  Arthritis and rheumatism 2004 Jawaheer D, Lum RF, Amos CI, Gregersen PK, Criswell LA
• Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritis.
  Arthritis and rheumatism 2004 Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell LA
• Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients.
  Arthritis and rheumatism 2004 Gorman JD, Lum RF, Chen JJ, Suarez-Almazor ME, Thomson G, Criswell LA
• The systemic lupus erythematosus-associated PDCD1 polymorphism PD1.3A in lupus nephritis.
  Arthritis and rheumatism 2004 Prokunina L, Gunnarsson I, Sturfelt G, Truedsson L, Seligman VA, Olson JL, Seldin MF, Criswell LA, Alarcón-Riquelme ME
• Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study.
  Arthritis and rheumatism 2004 Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell LA, Saag KG, Iowa Women's Health Study
• Mexican American ancestry-informative markers: examination of population structure and marker characteristics in European Americans, Mexican Americans, Amerindians and Asians.
  Human genetics 2003 Collins-Schramm HE, Chima B, Morii T, Wah K, Figueroa Y, Criswell LA, Hanson RL, Knowler WC, Silva G, Belmont JW, Seldin MF
• Estrogen and other female reproductive risk factors are not strongly associated with the development of rheumatoid arthritis in elderly women.
  Seminars in arthritis and rheumatism 2003 Merlino LA, Cerhan JR, Criswell LA, Mikuls TR, Saag KG
• Markers informative for ancestry demonstrate consistent megabase-length linkage disequilibrium in the African American population.
  Human genetics 2003 Collins-Schramm HE, Chima B, Operario DJ, Criswell LA, Seldin MF
• Health related quality of life in women with elderly onset rheumatoid arthritis.
  The Journal of rheumatology 2003 Mikuls T, Saag K, Criswell L, Merlino L, Cerhan JR
• Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families.
  Arthritis and rheumatism 2003 Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Etzel C, Damle A, Xiao X, Chen D, Lum RF, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW, Bridges SL, Pisetsky…
• Gender and racial differences in rates of total hip replacement.
  The Journal of bone and joint surgery. American volume 2003 Hoaglund FT, Criswell LA, Seldin MF
• Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women.
  American journal of epidemiology 2003 Cerhan JR, Saag KG, Merlino LA, Mikuls TR, Criswell LA
• Clinical usefulness of genetic information for predicting radiographic damage in rheumatoid arthritis.
  The Journal of rheumatology 2002 Chen JJ, Mu H, Jiang Y, King MC, Thomson G, Criswell LA
• Markers that discriminate between European and African ancestry show limited variation within Africa.
  Human genetics 2002 Collins-Schramm HE, Kittles RA, Operario DJ, Weber JL, Criswell LA, Cooper RS, Seldin MF
• Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis.
  American journal of human genetics 2002 Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, Monteiro J, Khalili H, Lee A, Lundsten R, Begovich A, Bugawan T, Erlich H, Elder JT, Criswell LA, Seldin MF, Amos CI, Behrens TW, Gregersen PK
• Demographic differences in the development of lupus nephritis: a retrospective analysis.
  The American journal of medicine 2002 Seligman VA, Lum RF, Olson JL, Li H, Criswell LA
• Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: results from the Iowa Women's Health Study.
  The American journal of medicine 2002 Criswell LA, Merlino LA, Cerhan JR, Mikuls TR, Mudano AS, Burma M, Folsom AR, Saag KG
• Blood transfusion, alcohol use, and anthropometric risk factors for rheumatoid arthritis in older women.
  The Journal of rheumatology 2002 Cerhan JR, Saag KG, Criswell LA, Merlino LA, Mikuls TR
• The shared epitope and severity of rheumatoid arthritis.
  Rheumatic diseases clinics of North America 2002 Gorman JD, Criswell LA
• Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study.
  Arthritis and rheumatism 2002 Mikuls TR, Cerhan JR, Criswell LA, Merlino L, Mudano AS, Burma M, Folsom AR, Saag KG