Linda Giudice, MD, PhD
Professor
Ob/Gyn, Reproductive Sciences
School of Medicine

Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.

• A Plain Language Summary to learn about relugolix combination therapy for the treatment of pain associated with endometriosis.
  Pain management 2023 Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Dynowski K, Wilk K, Li Y, Mathur V, Wagman RB, Johnson NP
• Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Giudice LC, Oskotsky TT, Falako S, Opoku-Anane J, Sirota M
• Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function.
  Communications biology 2023 Mortlock S, Houshdaran S, Kosti I, Rahmioglu N, Nezhat C, Vitonis AF, Andrews SV, Grosjean P, Paranjpe M, Horne AW, Jacoby A, Lager J, Opoku-Anane J, Vo KC, Manvelyan E, Sen S, Ghukasyan Z, Collins F,…
• B-cell lymphoma 6 expression significantly differs by the uterine preparation method used for frozen embryo transfer.
  Fertility and sterility 2023 Huang D, Chan M, Solomon M, Cedars MI, Giudice LC, Cakmak H
• Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study.
  Research square 2023 Roger J, Xie F, Costello J, Tang A, Liu J, Oskotsky T, Woldemariam S, Kosti I, Le B, Snyder MP, Giudice LC, Torgerson D, Shaw GM, Stevenson DK, Rajkovic A, Glymour MM, Aghaeepour N, Cakmak H, Lathi RB…
• The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions.
  Nature genetics 2023 Rahmioglu N, Mortlock S, Ghiasi M, Møller PL, Stefansdottir L, Galarneau G, Turman C, Danning R, Law MH, Sapkota Y, Christofidou P, Skarp S, Giri A, Banasik K, Krassowski M, Lepamets M, Marciniak B, …
• Systematic review of climate change effects on reproductive health.
  Fertility and sterility 2022 Segal TR, Giudice LC
• Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2).
  Lancet (London, England) 2022 Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Brown E, Dynowski K, Wilk K, Li Y, Mathur V, Warsi QA, Wagman RB, Johnson NP
• Response to Boulicault et al. (2022) from women in the field.
  Human fertility (Cambridge, England) 2022 Gore AC, Giudice LC, Flaws JA, Hunt PA
• Commentary on the climate crisis and Women's health: Time for action.
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2022 Giudice LC
• Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
  Reproductive biomedicine online 2022 Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC
• The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
  Science (New York, N.Y.) 2022 Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, …
• Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood.
  BMC medicine 2022 Vallvé-Juanico J, George AF, Sen S, Thomas R, Shin MG, Kushnoor D, Vásquez JJ, Vo KC, Irwin JC, Roan NR, Combes AJ, Giudice LC
• Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO.
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2022 Corbett GA, Lee S, Woodruff TJ, Hanson M, Hod M, Charlesworth AM, Giudice L, Conry J, McAuliffe FM, International Federation of Gynecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Lon
• Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis.
  Frontiers in immunology 2022 Bunis DG, Wang W, Vallvé-Juanico J, Houshdaran S, Sen S, Ben Soltane I, Kosti I, Vo KC, Irwin JC, Giudice LC, Sirota M
• Climate change, women's health, and the role of obstetricians and gynecologists in leadership.
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2021 Giudice LC, Llamas-Clark EF, DeNicola N, Pandipati S, Zlatnik MG, Decena DCD, Woodruff TJ, Conry JA, FIGO Committee on Climate Change and Toxic Environmental Exposures
• Environmental impact on reproductive health and risk mitigating strategies.
  Current opinion in obstetrics & gynecology 2021 Giudice LC
• Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area.
  Chemosphere 2021 Velarde MC, Chan AFO, Sajo MEJV, Zakharevich I, Melamed J, Uy GLB, Teves JMY, Corachea AJM, Valparaiso AP, Macalindong SS, Cabaluna ND, Dofitas RB, Giudice LC, Gerona RR
• In Silico, In Vitro, and In Vivo Analysis Identifies Endometrial Circadian Clock Genes in Recurrent Implantation Failure.
  The Journal of clinical endocrinology and metabolism 2021 Zhai J, Li S, Hu J, Gao M, Sun Y, Chen ZJ, Giudice LC, Du Y
• Endometrial function in women with polycystic ovary syndrome: a comprehensive review.
  Human reproduction update 2021 Palomba S, Piltonen TT, Giudice LC
• Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection.
  The New England journal of medicine 2021 Page K, Melia MT, Veenhuis RT, Winter M, Rousseau KE, Massaccesi G, Osburn WO, Forman M, Thomas E, Thornton K, Wagner K, Vassilev V, Lin L, Lum PJ, Giudice LC, Stein E, Asher A, Chang S, Gorman R, …
• Could children born to mothers with COVID-19 be more prone to non-communicable diseases?
  Acta paediatrica (Oslo, Norway : 1992) 2021 Malamitsi-Puchner A, Briana DD, Giudice L, Di Renzo GC
• Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium.
  Molecular human reproduction 2021 Marla S, Mortlock S, Houshdaran S, Fung J, McKinnon B, Holdsworth-Carson SJ, Girling JE, Rogers PAW, Giudice LC, Montgomery GW
• Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors.
  Human fertility (Cambridge, England) 2021 Manvelyan E, Houshdaran S, Irwin JC, Giudice LC, Aghajanova L
• Eye to the Future in Adenomyosis Research.
  Seminars in reproductive medicine 2020 Halvorson LM, Giudice LC, Stewart EA
• Developing a core outcome set for future infertility research: an international consensus development study†  ‡.
  Human reproduction (Oxford, England) 2020 Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, …
• Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study†  ‡.
  Human reproduction (Oxford, England) 2020 Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW…
• Top 10 priorities for future infertility research: an international consensus development study†  ‡.
  Human reproduction (Oxford, England) 2020 Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, …
• Developing a core outcome set for future infertility research: an international consensus development study.
  Fertility and sterility 2020 Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, …
• Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study.
  Fertility and sterility 2020 Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW…
• Top 10 priorities for future infertility research: an international consensus development study.
  Fertility and sterility 2020 Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, …
• Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics.
  Seminars in reproductive medicine 2020 Filby CE, Rombauts L, Montgomery GW, Giudice LC, Gargett CE
• Adenomyosis: Mechanisms and Pathogenesis.
  Seminars in reproductive medicine 2020 Zhai J, Vannuccini S, Petraglia F, Giudice LC
• Multidimensional transcriptomic mapping of human endometrium at single-cell resolution.
  Nature medicine 2020 Giudice LC
• Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNFα.
  Development (Cambridge, England) 2020 Taylor SK, Houshdaran S, Robinson JF, Gormley MJ, Kwan EY, Kapidzic M, Schilling B, Giudice LC, Fisher SJ
• The global impact of COVID-19 on infertility services.
  Global reproductive health 2020 Ory SJ, Miller KA, Horton M, Giudice L
• m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis.
  Frontiers in genetics 2020 Zhai J, Li S, Sen S, Opoku-Anane J, Du Y, Chen ZJ, Giudice LC
• Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis.
  PLoS genetics 2020 Houshdaran S, Oke AB, Fung JC, Vo KC, Nezhat C, Giudice LC
• A Clarion Warning About Pregnancy Outcomes and the Climate Crisis.
  JAMA network open 2020 Giudice LC
• HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread.
  eLife 2020 Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR
• Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosa of HIV-infected women.
  American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL
• Authors' Reply.
  Journal of minimally invasive gynecology 2020 Montgomery GW, Mortlock S, Giudice LC
• Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome.
  Scientific reports 2020 Smith-McCune K, Thomas R, Averbach S, Seidman D, Takeda M, Houshdaran S, Giudice LC
• Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions.
  International journal of molecular sciences 2020 Houshdaran S, Chen JC, Vallvé-Juanico J, Balayan S, Vo KC, Smith-McCune K, Greenblatt RM, Irwin JC, Giudice LC
• Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.
  Human reproduction (Oxford, England) 2020 George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR
• A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience.
  Biopreservation and biobanking 2020 Sajo MEJV, Teves JMY, Corachea AJM, Diaz LA, Chan AFO, Valparaiso AP, Dy Echo AVV, Macalindong SS, Uy GLB, Dofitas RB, Habana MAE, Gerona RR, Irwin JC, Giudice LC, Velarde MC
• Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease.
  Fertility and sterility 2019 Vallvé-Juanico J, Santamaria X, Vo KC, Houshdaran S, Giudice LC
• Should Genetics Now Be Considered the Pre-eminent Etiologic Factor in Endometriosis?
  Journal of minimally invasive gynecology 2019 Montgomery GW, Mortlock S, Giudice LC
• 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility.
  Fertility and sterility 2019 Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, …
• Before the beginning: environmental exposures and reproductive and obstetrical outcomes.
  Fertility and sterility 2019 Segal TR, Giudice LC
• Reprint of: Pathogenesis and pathophysiology of endometriosis.
  Fertility and sterility 2019 Burney RO, Giudice LC
• The endometrial immune environment of women with endometriosis.
  Human reproduction update 2019 Vallvé-Juanico J, Houshdaran S, Giudice LC
• Assessing research gaps and unmet needs in endometriosis.
  American journal of obstetrics and gynecology 2019 As-Sanie S, Black R, Giudice LC, Gray Valbrun T, Gupta J, Jones B, Laufer MR, Milspaw AT, Missmer SA, Norman A, Taylor RN, Wallace K, Williams Z, Yong PJ, Nebel RA
• Clinical diagnosis of endometriosis: a call to action.
  American journal of obstetrics and gynecology 2019 Agarwal SK, Chapron C, Giudice LC, Laufer MR, Leyland N, Missmer SA, Singh SS, Taylor HS
• Establishing the global working group on Reproductive and Developmental Environmental Health (RDEH): practicum of a global resource.
  Global reproductive health 2018 Power AM, Woodruff TJ, Conry JA, Giudice LC
• Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma.
  Biology of reproduction 2018 Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR
• Forty years of IVF.
  Fertility and sterility 2018 Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, …
• Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies.
  Obstetrics and gynecology 2018 Surrey E, Taylor HS, Giudice L, Lessey BA, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, …
• Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation.
  Contemporary clinical trials 2018 Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H, NICHD Cooperative Reproductive Medicine Network
• In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration.
  Journal of assisted reproduction and genetics 2018 Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC
• Effects of noncavity-distorting fibroids on endometrial gene expression and function.
  Biology of reproduction 2017 Aghajanova L, Houshdaran S, Irwin JC, Giudice LC
• Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium.
  Biology of reproduction 2017 Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC
• Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers.
  Scientific reports 2017 Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets …
• Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist.
  The New England journal of medicine 2017 Taylor HS, Giudice LC, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel…
• New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity.
  The New England journal of medicine 2017 Montgomery GW, Giudice LC
• Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
  PLoS pathogens 2017 Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, …
• Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility.
  Mucosal immunology 2017 Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL
• World Endometriosis Society consensus on the classification of endometriosis.
  Human reproduction (Oxford, England) 2016 Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice LC, World Endometriosis Society Sao Paulo Consortium
• Insights from imaging the implanting embryo and the uterine environment in three dimensions.
  Development (Cambridge, England) 2016 Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ
• Challenging dogma: the endometrium has a microbiome with functional consequences!
  American journal of obstetrics and gynecology 2016 Giudice LC
• Research Priorities for Endometriosis.
  Reproductive sciences (Thousand Oaks, Calif.) 2016 Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, …
• Environmental toxicants: hidden players on the reproductive stage.
  Fertility and sterility 2016 Giudice LC
• Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis.
  Biology of reproduction 2016 Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC
• Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium.
  American journal of reproductive immunology (New York, N.Y. : 1989) 2016 Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K
• Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis.
  Fertility and sterility 2016 Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice LC
• Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis.
  Reproductive sciences (Thousand Oaks, Calif.) 2016 Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice LC
• Moving from awareness to action on preventing patient exposure to toxic environmental chemicals.
  American journal of obstetrics and gynecology 2016 Sutton PM, Giudice LC, Woodruff TJ
• Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis.
  Biology of reproduction 2016 Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC
• Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity.
  Fertility and sterility 2015 Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC
• International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals.
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2015 Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice LC
• Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome.
  Human reproduction update 2015 Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F
• Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012".
  Regulatory toxicology and pharmacology : RTP 2015 Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross…
• Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study.
  PloS one 2015 Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC
• Update on Biomarkers for the Detection of Endometriosis.
  BioMed research international 2015 Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L
• Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal.
  Human reproduction (Oxford, England) 2015 Vercellini P, Giudice LC, Evers JL, Abrao MS
• Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis.
  Biology of reproduction 2015 Heard ME, Velarde MC, Giudice LC, Simmen FA, Simmen RC
• Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro.
  Human reproduction (Oxford, England) 2015 Piltonen TT, Chen JC, Khatun M, Kangasniemi M, Liakka A, Spitzer T, Tran N, Huddleston H, Irwin JC, Giudice LC
• Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix.
  Reproductive sciences (Thousand Oaks, Calif.) 2015 Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC
• Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals.
  Journal of proteomics 2014 Williams KE, Miroshnychenko O, Johansen EB, Niles RK, Sundaram R, Kannan K, Albertolle M, Zhou Y, Prasad N, Drake PM, Giudice LC, Hall SC, Witkowska HE, Buck Louis GM, Fisher SJ
• Molecular classification of endometriosis and disease stage using high-dimensional genomic data.
  Endocrinology 2014 Tamaresis JS, Irwin JC, Goldfien GA, Rabban JT, Burney RO, Nezhat C, DePaolo LV, Giudice LC
• World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research.
  Fertility and sterility 2014 Fassbender A, Rahmioglu N, Vitonis AF, Viganò P, Giudice LC, D'Hooghe TM, Hummelshoj L, Adamson GD, Becker CM, Missmer SA, Zondervan KT, WERF EPHect Working Group
• World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research.
  Fertility and sterility 2014 Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice LC, Stratton P, Adamson GD, Becker CM, Zondervan KT, Missmer SA, WERF EPHect Working Group
• World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research.
  Fertility and sterility 2014 Rahmioglu N, Fassbender A, Vitonis AF, Tworoger SS, Hummelshoj L, D'Hooghe TM, Adamson GD, Giudice LC, Becker CM, Zondervan KT, Missmer SA, WERF EPHect Working Group
• Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation.
  Molecular endocrinology (Baltimore, Md.) 2014 Houshdaran S, Zelenko Z, Irwin JC, Giudice LC
• Impact of surgical excision of lesions on pain in a rat model of endometriosis.
  European journal of pain (London, England) 2014 Alvarez P, Giudice LC, Levine JD
• Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.
  Human reproduction (Oxford, England) 2014 Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR
• Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women.
  American journal of reproductive immunology (New York, N.Y. : 1989) 2013 Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL
• Ectopic endometrium-derived leptin produces estrogen-dependent chronic pain in a rat model of endometriosis.
  Neuroscience 2013 Alvarez P, Bogen O, Chen X, Giudice LC, Levine JD
• Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium.
  Human reproduction update 2013 Altmäe S, Esteban FJ, Stavreus-Evers A, Simón C, Giudice L, Lessey BA, Horcajadas JA, Macklon NS, D'Hooghe T, Campoy C, Fauser BC, Salamonsen LA, Salumets A
• Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors.
  Environmental health : a global access science source 2013 Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A…
• Elagolix, an Oral GnRH Antagonist for Endometriosis-Associated Pain: A Randomized Controlled Study.
  Journal of endometriosis and pelvic pain disorders 2013 Carr B, Giudice L, Dmowski WP, O'Brien C, Jiang P, Burke J, Jimenez R, Hass S, Fuldeore M, Chwalisz K
• The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit.
  Reproductive biomedicine online 2013 Hess AP, Talbi S, Hamilton AE, Baston-Buest DM, Nyegaard M, Irwin JC, Barragan F, Kruessel JS, Germeyer A, Giudice LC
• Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production.
  Fertility and sterility 2013 Chen JC, Erikson DW, Piltonen TT, Meyer MR, Barragan F, McIntire RH, Tamaresis JS, Vo KC, Giudice LC, Irwin JC
• Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential.
  The Journal of clinical endocrinology and metabolism 2013 Piltonen TT, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC
• Diversity of the vaginal microbiome correlates with preterm birth.
  Reproductive sciences (Thousand Oaks, Calif.) 2013 Hyman RW, Fukushima M, Jiang H, Fung E, Rand L, Johnson B, Vo KC, Caughey AB, Hilton JF, Davis RW, Giudice LC
• Retrospective. Robert G. Edwards (1925-2013).
  Science (New York, N.Y.) 2013 Fisher SJ, Giudice LC
• Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study.
  Fertility and sterility 2013 Buck Louis GM, Peterson CM, Chen Z, Croughan M, Sundaram R, Stanford J, Varner MW, Kennedy A, Giudice L, Fujimoto VY, Sun L, Wang L, Guo Y, Kannan K
• Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis.
  Biology of reproduction 2013 Afshar Y, Hastings J, Roqueiro D, Jeong JW, Giudice LC, Fazleabas AT
• Defining future directions for endometriosis research: workshop report from the 2011 World Congress of Endometriosis In Montpellier, France.
  Reproductive sciences (Thousand Oaks, Calif.) 2013 Rogers PA, D'Hooghe TM, Fazleabas A, Giudice LC, Montgomery GW, Petraglia F, Taylor RN
• Perfluorochemicals and endometriosis: the ENDO study.
  Epidemiology (Cambridge, Mass.) 2012 Louis GM, Peterson CM, Chen Z, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Fujimoto VY, Varner MW, Giudice LC, Kennedy A, Sun L, Wu Q, Kannan K
• Role of decreased androgens in the ovarian response to stimulation in older women.
  Fertility and sterility 2012 Meldrum DR, Chang RJ, Giudice LC, Balasch J, Barbieri RL
• Ectopic uterine tissue as a chronic pain generator.
  Neuroscience 2012 Alvarez P, Chen X, Hendrich J, Irwin JC, Green PG, Giudice LC, Levine JD
• Pathogenesis and pathophysiology of endometriosis.
  Fertility and sterility 2012 Burney RO, Giudice LC
• Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study.
  Environmental health perspectives 2012 Buck Louis GM, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LC, Trumble A, Parsons PJ, Kannan K
• Molecular probe technology detects bacteria without culture.
  BMC microbiology 2012 Hyman RW, St Onge RP, Kim H, Tamaresis JS, Miranda M, Aparicio AM, Fukushima M, Pourmand N, Giudice LC, Davis RW
• Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures.
  American journal of obstetrics and gynecology 2012 Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice LC
• Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.
  Biology of reproduction 2012 Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice LC
• Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis.
  The Journal of clinical endocrinology and metabolism 2012 Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice LC, Simmen RC
• Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation.
  Biology of reproduction 2012 Aghajanova L, Shen S, Rojas AM, Fisher SJ, Irwin JC, Giudice LC
• The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer.
  Journal of assisted reproduction and genetics 2012 Hyman RW, Herndon CN, Jiang H, Palm C, Fukushima M, Bernstein D, Vo KC, Zelenko Z, Davis RW, Giudice LC
• High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples.
  Human reproduction (Oxford, England) 2012 Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR, Reproductive …
• Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis.
  Reproductive sciences (Thousand Oaks, Calif.) 2011 Zelenko Z, Aghajanova L, Irwin JC, Giudice LC
• A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder.
  American heart journal 2011 White WB, Grady D, Giudice LC, Berry SM, Zborowski J, Snabes MC
• SGK1: a fine balancing act for human pregnancy.
  Nature medicine 2011 Fisher SJ, Giudice LC
• Incidence of endometriosis by study population and diagnostic method: the ENDO study.
  Fertility and sterility 2011 Buck Louis GM, Hediger ML, Peterson CM, Croughan M, Sundaram R, Stanford J, Chen Z, Fujimoto VY, Varner MW, Trumble A, Giudice LC, ENDO Study Working Group
• Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
  The Journal of clinical endocrinology and metabolism 2011 Savaris RF, Groll JM, Young SL, DeMayo FJ, Jeong JW, Hamilton AE, Giudice LC, Lessey BA
• Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development.
  Fertility and sterility 2011 Sheldon E, Vo KC, McIntire RA, Aghajanova L, Zelenko Z, Irwin JC, Giudice LC
• Transcriptomic signature of trophoblast differentiation in a human embryonic stem cell model.
  Biology of reproduction 2011 Marchand M, Horcajadas JA, Esteban FJ, McElroy SL, Fisher SJ, Giudice LC
• Effect of bisphenol A on human endometrial stromal fibroblasts in vitro.
  Reproductive biomedicine online 2010 Aghajanova L, Giudice LC
• Reproductive environmental health.
  Current opinion in obstetrics & gynecology 2010 Sutton P, Giudice LC, Woodruff TJ
• Molecular evidence for differences in endometrium in severe versus mild endometriosis.
  Reproductive sciences (Thousand Oaks, Calif.) 2010 Aghajanova L, Giudice LC
• Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
  Biology of reproduction 2010 Aghajanova L, Tatsumi K, Horcajadas JA, Zamah AM, Esteban FJ, Herndon CN, Conti M, Giudice LC
• "The curse": a 21st century perspective of models of its molecular basis.
  Endocrinology 2010 Salamonsen LA, Giudice LC
• Clinical practice. Endometriosis.
  The New England journal of medicine 2010 Giudice LC
• Racial and ethnic disparities in benign gynecologic conditions and associated surgeries.
  American journal of obstetrics and gynecology 2010 Jacoby VL, Fujimoto VY, Giudice LC, Kuppermann M, Washington AE
• Research agenda for environmental reproductive health in the 21st century.
  Journal of epidemiology and community health 2010 Woodruff TJ, Schwartz J, Giudice LC
• Racial and ethnic disparities in reproductive endocrinology and infertility.
  American journal of obstetrics and gynecology 2010 Huddleston HG, Cedars MI, Sohn SH, Giudice LC, Fujimoto VY
• Research ethics. NIH guidelines for stem cell research and gamete donors.
  Science (New York, N.Y.) 2010 Lo B, Parham L, Cedars M, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Rao R, Roberts C, Wagner R
• The bone marrow-derived human mesenchymal stem cell: potential progenitor of the endometrial stromal fibroblast.
  Biology of reproduction 2010 Aghajanova L, Horcajadas JA, Esteban FJ, Giudice LC
• Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility.
  Biology of reproduction 2010 Nyegaard M, Overgaard MT, Su YQ, Hamilton AE, Kwintkiewicz J, Hsieh M, Nayak NR, Conti M, Conover CA, Giudice LC
• Altered gene expression profiling in endometrium: evidence for progesterone resistance.
  Seminars in reproductive medicine 2010 Aghajanova L, Velarde MC, Giudice LC
• The protein kinase A pathway-regulated transcriptome of endometrial stromal fibroblasts reveals compromised differentiation and persistent proliferative potential in endometriosis.
  Endocrinology 2010 Aghajanova L, Horcajadas JA, Weeks JL, Esteban FJ, Nezhat CN, Conti M, Giudice LC
• Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.
  Cell stem cell 2010 Lo B, Parham L, Alvarez-Buylla A, Cedars M, Conklin B, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Wagner R
• Gene expression during successful implantation in a natural cycle.
  Fertility and sterility 2009 Van Vaerenbergh I, McIntire R, Van Lommel L, Devroey P, Giudice L, Bourgain C
• Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells.
  Environmental health perspectives 2009 Kwintkiewicz J, Nishi Y, Yanase T, Giudice LC
• MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis.
  Molecular human reproduction 2009 Burney RO, Hamilton AE, Aghajanova L, Vo KC, Nezhat CN, Lessey BA, Giudice LC
• Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1.
  Endocrinology 2009 Velarde MC, Aghajanova L, Nezhat CR, Giudice LC
• Body mass index and intercourse compliance.
  Fertility and sterility 2009 Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC, National Institute of …
• Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial.
  Fertility and sterility 2009 Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC, National Institute of …
• Predictors of pregnancy in women with polycystic ovary syndrome.
  The Journal of clinical endocrinology and metabolism 2009 Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Coutifaris C, …
• Endocrine-disrupting chemicals: an Endocrine Society scientific statement.
  Endocrine reviews 2009 Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC
• Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ
• Editorial: Update on stem cell research.
  Endocrine reviews 2009 Robertson RP, Giudice LC
• The progesterone receptor coactivator Hic-5 is involved in the pathophysiology of endometriosis.
  Endocrinology 2009 Aghajanova L, Velarde MC, Giudice LC
• Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns.
  Cell stem cell 2009 Lo B, Parham L, Broom C, Cedars M, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Oberman M, Roberts C, Wagner R
• Priorities for endometriosis research: recommendations from an international consensus workshop.
  Reproductive sciences (Thousand Oaks, Calif.) 2009 Rogers PA, D'Hooghe TM, Fazleabas A, Gargett CE, Giudice LC, Montgomery GW, Rombauts L, Salamonsen LA, Zondervan KT
• The interplay of insulin-like growth factors, gonadotropins, and endocrine disruptors in ovarian follicular development and function.
  Seminars in reproductive medicine 2009 Kwintkiewicz J, Giudice LC
• Genomics analysis: endometrium.
  Methods in molecular biology (Clifton, N.J.) 2009 Savaris RF, Giudice LC
• From stem cells to germ cells and back again.
  Nature medicine 2008 Conti M, Giudice L
• Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.
  Fertility and sterility 2008 Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ
• Steroidogenic enzyme and key decidualization marker dysregulation in endometrial stromal cells from women with versus without endometriosis.
  Biology of reproduction 2008 Aghajanova L, Hamilton A, Kwintkiewicz J, Vo KC, Giudice LC
• Environmental exposures and adverse pregnancy outcomes: a review of the science.
  Reproductive sciences (Thousand Oaks, Calif.) 2008 Stillerman KP, Mattison DR, Giudice LC, Woodruff TJ
• Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications.
  The Journal of clinical endocrinology and metabolism 2008 Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice LC, Pellicer A, Simón C
• VEGF blockade inhibits angiogenesis and reepithelialization of endometrium.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR
• Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy.
  Reproductive sciences (Thousand Oaks, Calif.) 2008 Savaris RF, Hamilton AE, Lessey BA, Giudice LC
• Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome.
  The Journal of clinical endocrinology and metabolism 2008 Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC, Reproductive Medicine Network
• Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer.
  Reproductive biomedicine online 2008 McElroy SL, Kee K, Tran N, Menses J, Giudice LC, Reijo Pera RA
• The impact of ovarian stimulation with recombinant FSH in combination with GnRH antagonist on the endometrial transcriptome in the window of implantation.
  Reproductive sciences (Thousand Oaks, Calif.) 2008 Macklon NS, van der Gaast MH, Hamilton A, Fauser BC, Giudice LC
• Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary.
  Fertility and sterility 2008 Woodruff TJ, Carlson A, Schwartz JM, Giudice LC
• Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary.
  Fertility and sterility 2008 Woodruff TJ, Carlson A, Schwartz JM, Giudice LC
• Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone.
  The Journal of endocrinology 2008 Dosiou C, Hamilton AE, Pang Y, Overgaard MT, Tulac S, Dong J, Thomas P, Giudice LC
• Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial.
  Fertility and sterility 2007 McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC, National Institute of …
• Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene.
  The Journal of clinical endocrinology and metabolism 2007 Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Ewens KG, Spielman RS, Leppert PC, Myers ER,…
• The influence of hydrosalpinx on markers of endometrial receptivity.
  Seminars in reproductive medicine 2007 Savaris RF, Giudice LC
• Uterine receptivity to human embryonic implantation: histology, biomarkers, and transcriptomics.
  Seminars in cell & developmental biology 2007 Aghajanova L, Hamilton AE, Giudice LC
• Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis.
  Endocrinology 2007 Burney RO, Talbi S, Hamilton AE, Vo KC, Nyegaard M, Nezhat CR, Lessey BA, Giudice LC
• Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.
  The New England journal of medicine 2007 Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Cooperative …
• Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.
  Fertility and sterility 2006 McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC, National Institutes for Child …
• Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators.
  Biology of reproduction 2006 Hess AP, Hamilton AE, Talbi S, Dosiou C, Nyegaard M, Nayak N, Genbecev-Krtolica O, Mavrogianis P, Ferrer K, Kruessel J, Fazleabas AT, Fisher SJ, Giudice LC
• Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
  The Journal of clinical investigation 2006 Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ
• Participation of mitogen-activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles.
  Biology of reproduction 2006 Su YQ, Nyegaard M, Overgaard MT, Qiao J, Giudice LC
• Infertility and the environment: the medical context.
  Seminars in reproductive medicine 2006 Giudice LC
• A twenty-first century research agenda for polycystic ovary syndrome.
  Best practice & research. Clinical endocrinology & metabolism 2006 Legro RS, Azziz R, Giudice L
• Endometrium in PCOS: Implantation and predisposition to endocrine CA.
  Best practice & research. Clinical endocrinology & metabolism 2006 Giudice LC
• Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells.
  The Journal of clinical endocrinology and metabolism 2006 Tulac S, Overgaard MT, Hamilton AE, Jumbe NL, Suchanek E, Giudice LC
• The science behind 25 years of ovarian stimulation for in vitro fertilization.
  Endocrine reviews 2006 Macklon NS, Stouffer RL, Giudice LC, Fauser BC
• Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth.
  Molecular human reproduction 2006 Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM
• Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.
  Reproduction, fertility, and development 2006 Hess AP, Hirchenhain J, Schanz A, Talbi S, Hamilton AE, Giudice LC, Krüssel JS
• Application of functional genomics to primate endometrium: insights into biological processes.
  Reproductive biology and endocrinology : RB&E 2006 Giudice LC
• Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
  Lymphatic research and biology 2006 Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ
• Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles.
  Fertility and sterility 2005 Littman E, Giudice L, Lathi R, Berker B, Milki A, Nezhat C
• The dilemma of endometriosis: is consensus possible with an enigma?
  Fertility and sterility 2005 Nezhat C, Littman ED, Lathi RB, Berker B, Westphal LM, Giudice LC, Milki AA
• Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women.
  Endocrinology 2005 Talbi S, Hamilton AE, Vo KC, Tulac S, Overgaard MT, Dosiou C, Le Shay N, Nezhat CN, Kempson R, Lessey BA, Nayak NR, Giudice LC
• IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch.
  Molecular human reproduction 2005 Li T, Vu TH, Ulaner GA, Littman E, Ling JQ, Chen HL, Hu JF, Behr B, Giudice L, Hoffman AR
• Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome.
  Human reproduction (Oxford, England) 2005 Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice LC, Reaven GM
• Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.
  Endocrinology 2005 Tang M, Mikhailik A, Pauli I, Giudice LC, Fazelabas AT, Tulac S, Carson DD, Kaufman DG, Barbier C, Creemers JW, Tabibzadeh S
• Microbes on the human vaginal epithelium.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Hyman RW, Fukushima M, Diamond L, Kumm J, Giudice LC, Davis RW
• Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives.
  Endocrine reviews 2005 Dosiou C, Giudice LC
• Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements.
  The Journal of biological chemistry 2005 Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice LC, Oxvig C
• Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium.
  The Journal of clinical endocrinology and metabolism 2004 Germeyer A, Hamilton AE, Laughlin LS, Lasley BL, Brenner RM, Giudice LC, Nayak NR
• Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways.
  The Journal of clinical endocrinology and metabolism 2004 Lathi RB, Hess AP, Tulac S, Nayak NR, Conti M, Giudice LC
• Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.
  Fertility and sterility 2004 McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice LC, Leppert PC, Diamond MP, NICHD National Cooperative Reproductive Medicine Network
• Endometriosis.
  Lancet (London, England) 2004 Giudice LC, Kao LC
• The immune environment in human endometrium during the window of implantation.
  American journal of reproductive immunology (New York, N.Y. : 1989) 2004 Lobo SC, Huang ST, Germeyer A, Dosiou C, Vo KC, Tulac S, Nayak NR, Giudice LC
• Silencing lamin A/C in human endometrial stromal cells: a model to investigate endometrial gene function and regulation.
  Molecular human reproduction 2004 Tulac S, Dosiou C, Suchanek E, Giudice LC
• Developmental response to hypoxia.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Huang ST, Vo KC, Lyell DJ, Faessen GH, Tulac S, Tibshirani R, Giaccia AJ, Giudice LC
• The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.
  The Journal of biological chemistry 2004 Boldt HB, Kjaer-Sorensen K, Overgaard MT, Weyer K, Poulsen CB, Sottrup-Jensen L, Conover CA, Giudice LC, Oxvig C
• Interferon-related and other immune genes are downregulated in peripheral blood leukocytes in the luteal phase of the menstrual cycle.
  The Journal of clinical endocrinology and metabolism 2004 Dosiou C, Lathi RB, Tulac S, Huang ST, Giudice LC
• Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.
  European journal of biochemistry 2004 Weyer K, Overgaard MT, Laursen LS, Nielsen CG, Schmitz A, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C
• Role of activin A as a mediator of in vitro endometrial stromal cell decidualization via the cyclic adenosine monophosphate pathway.
  Fertility and sterility 2004 Tierney EP, Giudice LC
• Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase.
  FEBS letters 2004 Overgaard MT, Glerup S, Boldt HB, Rodacker V, Olsen IM, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C
• Microarray expression profiling reveals candidate genes for human uterine receptivity.
  American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2004 Giudice LC
• Activation of the protein kinase A pathway in human endometrial stromal cells reveals sequential categorical gene regulation.
  Physiological genomics 2003 Tierney EP, Tulac S, Huang ST, Giudice LC
• Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer.
  Journal of assisted reproduction and genetics 2003 Milki AA, Jun SH, Hinckley MD, Westphal LW, Giudice LC, Behr B
• Identification, characterization, and regulation of the canonical Wnt signaling pathway in human endometrium.
  The Journal of clinical endocrinology and metabolism 2003 Tulac S, Nayak NR, Kao LC, Van Waes M, Huang J, Lobo S, Germeyer A, Lessey BA, Taylor RN, Suchanek E, Giudice LC
• Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility.
  Endocrinology 2003 Kao LC, Germeyer A, Tulac S, Lobo S, Yang JP, Taylor RN, Osteen K, Lessey BA, Giudice LC
• Prenatal screening, epidemiology, diagnosis, and management of preeclampsia.
  Clinics in laboratory medicine 2003 Lyell DJ, Lambert-Messerlian GM, Giudice LC
• Elucidating endometrial function in the post-genomic era.
  Human reproduction update 2003 Giudice LC
• Genomics' role in understanding the pathogenesis of endometriosis.
  Seminars in reproductive medicine 2003 Giudice LC
• Comparative biology of the IGF system in endometrium, decidua, and placenta, and clinical implications for foetal growth and implantation disorders.
  Placenta 2003 Nayak NR, Giudice LC
• Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer.
  Fertility and sterility 2003 Milki AA, Jun SH, Hinckley MD, Behr B, Giudice LC, Westphal LM
• Regulation of insulin-like growth factor-I and insulin-like growth factor binding protein-1 concentrations in preterm fetuses.
  American journal of obstetrics and gynecology 2003 Verhaeghe J, Van Herck E, Billen J, Moerman P, Van Assche FA, Giudice LC
• Predictors of ovulatory failure in women with epilepsy.
  Annals of neurology 2002 Morrell MJ, Giudice L, Flynn KL, Seale CG, Paulson AJ, Doñe S, Flaster E, Ferin M, Sauer MV
• Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane.
  The Journal of clinical endocrinology and metabolism 2002 Sun IY, Overgaard MT, Oxvig C, Giudice LC
• Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.
  The Journal of biological chemistry 2002 Laursen LS, Overgaard MT, Weyer K, Boldt HB, Ebbesen P, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C
• Emerging role of genomics in endometriosis research.
  Fertility and sterility 2002 Taylor RN, Lundeen SG, Giudice LC
• Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis.
  The Biochemical journal 2002 Laursen LS, Overgaard MT, Nielsen CG, Boldt HB, Hopmann KH, Conover CA, Sottrup-Jensen L, Giudice LC, Oxvig C
• Maternal-fetal conflict--lessons from a transgene.
  The Journal of clinical investigation 2002 Giudice LC
• Global gene profiling in human endometrium during the window of implantation.
  Endocrinology 2002 Kao LC, Tulac S, Lobo S, Imani B, Yang JP, Germeyer A, Osteen K, Taylor RN, Lessey BA, Giudice LC
• Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.
  The Journal of clinical endocrinology and metabolism 2002 Giudice LC, Conover CA, Bale L, Faessen GH, Ilg K, Sun I, Imani B, Suen LF, Irwin JC, Christiansen M, Overgaard MT, Oxvig C
• A longitudinal analysis of maternal serum insulin-like growth factor I (IGF-I) and total and nonphosphorylated IGF-binding protein-1 in human pregnancies complicated by intrauterine growth restriction.
  The Journal of clinical endocrinology and metabolism 2002 Bhatia S, Faessen GH, Carland G, Balise RL, Gargosky SE, Druzin M, El-Sayed Y, Wilson DM, Giudice LC
• Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.
  European journal of biochemistry 2002 Søe R, Overgaard MT, Thomsen AR, Laursen LS, Olsen IM, Sottrup-Jensen L, Haaning J, Giudice LC, Conover CA, Oxvig C
• The molecular basis for implantation failure in endometriosis: on the road to discovery.
  Annals of the New York Academy of Sciences 2002 Giudice LC, Telles TL, Lobo S, Kao L
• Prediction of the individual follicle-stimulating hormone threshold for gonadotropin induction of ovulation in normogonadotropic anovulatory infertility: an approach to increase safety and efficiency.
  Fertility and sterility 2002 Imani B, Eijkemans MJ, Faessen GH, Bouchard P, Giudice LC, Fauser BC
• Insulin-like growth factor-binding protein-1 in umbilical artery and vein of term fetuses with signs suggestive of distress during labor.
  The Journal of endocrinology 2001 Verhaeghe J, Billen J, Giudice LC
• Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A.
  FEBS letters 2001 Laursen LS, Overgaard MT, Søe R, Boldt HB, Sottrup-Jensen L, Giudice LC, Conover CA, Oxvig C
• A potential role for insulin-like growth factor binding protein-4 proteolysis in the establishment of ovarian follicular dominance in cattle.
  Biology of reproduction 2001 Rivera GM, Chandrasekher YA, Evans AC, Giudice LC, Fortune JE
• Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture: suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency.
  The Journal of clinical endocrinology and metabolism 2001 Popovici RM, Lu M, Bhatia S, Faessen GH, Giaccia AJ, Giudice LC
• Insulin-like growth factor (IGF)-II inhibition of endometrial stromal cell tissue inhibitor of metalloproteinase-3 and IGF-binding protein-1 suggests paracrine interactions at the decidua:trophoblast interface during human implantation.
  The Journal of clinical endocrinology and metabolism 2001 Irwin JC, Suen LF, Faessen GH, Popovici RM, Giudice LC
• Pregnancy-associated plasma protein-a is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the corpus luteum.
  Endocrinology 2001 Conover CA, Faessen GF, Ilg KE, Chandrasekher YA, Christiansen M, Overgaard MT, Oxvig C, Giudice LC
• Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development.
  International journal of cancer 2001 Ulaner GA, Hu JF, Vu TH, Giudice LC, Hoffman AR
• Insulin-like growth factor family in Graafian follicle development and function.
  Journal of the Society for Gynecologic Investigation 2001 Giudice LC
• Multiple pregnancies: what action should we take?
  Fertility and sterility 2001 Paulson RJ, Ory SJ, Giudice LC, Schlaff WD, Santoro NF, Coddington CC
• Ovarian follicular concentrations of activin, follistatin, inhibin, insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-2 (IGFBP-2), IGFBP-3, and vascular endothelial growth factor in spontaneous menstrual cycles of normal women of advanced reproductive age.
  The Journal of clinical endocrinology and metabolism 2000 Klein NA, Battaglia DE, Woodruff TK, Padmanabhan V, Giudice LC, Bremner WJ, Soules MR
• Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3',5'-cyclic adenosine monophosphate is additive in HepG2 cells.
  The Journal of clinical endocrinology and metabolism 2000 Sugawara J, Tazuke SI, Suen LF, Powell DR, Kaper F, Giaccia AJ, Giudice LC
• Discovery of new inducible genes in in vitro decidualized human endometrial stromal cells using microarray technology.
  Endocrinology 2000 Popovici RM, Kao LC, Giudice LC
• Regulation of insulin-like growth factor-binding protein-1 by nitric oxide under hypoxic conditions.
  The Journal of clinical endocrinology and metabolism 2000 Sugawara J, Suh DS, Faessen GH, Suen LF, Shibata T, Kaper F, Giaccia AJ, Giudice LC
• Free androgen index and leptin are the most prominent endocrine predictors of ovarian response during clomiphene citrate induction of ovulation in normogonadotropic oligoamenorrheic infertility.
  The Journal of clinical endocrinology and metabolism 2000 Imani B, Eijkemans MJ, de Jong FH, Payne NN, Bouchard P, Giudice LC, Fauser BC
• Human placental trophoblasts secrete a disintegrin metalloproteinase very similar to the insulin-like growth factor binding protein-3 protease in human pregnancy serum.
  Endocrinology 2000 Irwin JC, Suen LF, Cheng BH, Martin R, Cannon P, Deal CL, Giudice LC
• Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium.
  International journal of cancer 2000 Ulaner GA, Hu JF, Vu TH, Oruganti H, Giudice LC, Hoffman AR
• Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A.
  The Journal of clinical endocrinology and metabolism 1999 Conover CA, Oxvig C, Overgaard MT, Christiansen M, Giudice LC
• Potential biochemical markers of uterine receptivity.
  Human reproduction (Oxford, England) 1999 Giudice LC
• Role of the IGF system in trophoblast invasion and pre-eclampsia.
  Human reproduction (Oxford, England) 1999 Irwin JC, Suen LF, Martina NA, Mark SP, Giudice LC
• Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome.
  The Journal of clinical endocrinology and metabolism 1999 Thierry van Dessel HJ, Lee PD, Faessen G, Fauser BC, Giudice LC
• The insulin-related ovarian regulatory system in health and disease.
  Endocrine reviews 1999 Poretsky L, Cataldo NA, Rosenwaks Z, Giudice LC
• Growth factor action on ovarian function in polycystic ovary syndrome.
  Endocrinology and metabolism clinics of North America 1999 Giudice LC
• Hypoxia and cAMP stimulate vascular endothelial growth factor (VEGF) in human endometrial stromal cells: potential relevance to menstruation and endometrial regeneration.
  The Journal of clinical endocrinology and metabolism 1999 Popovici RM, Irwin JC, Giaccia AJ, Giudice LC
• Insulin-like growth factor-II mediates the steroidogenic and growth promoting actions of follicle stimulating hormone on human ovarian pre-antral follicles cultured in vitro.
  The Journal of clinical endocrinology and metabolism 1999 Yuan W, Giudice LC
• Genes associated with embryonic attachment and implantation and the role of progesterone.
  The Journal of reproductive medicine 1999 Giudice LC
• Roles of the insulinlike growth factor family in nonpregnant human endometrium and at the decidual: trophoblast interface.
  Seminars in reproductive endocrinology 1999 Giudice LC, Irwin JC
• Dysfunctional uterine bleeding.
  The Western journal of medicine 1998 Chen BH, Giudice LC
• Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
  Cancer research 1998 Ulaner GA, Hu JF, Vu TH, Giudice LC, Hoffman AR
• Growth factor regulation of insulin-like growth factor binding protein secretion by cultured human granulosa-luteal cells.
  Fertility and sterility 1998 Yap OW, Chandrasekher YA, Giudice LC
• Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia.
  Proceedings of the National Academy of Sciences of the United States of America 1998 Tazuke SI, Mazure NM, Sugawara J, Carland G, Faessen GH, Suen LF, Irwin JC, Powell DR, Giaccia AJ, Giudice LC
• Paracrine actions of insulin-like growth factors and IGF binding protein-1 in non-pregnant human endometrium and at the decidual-trophoblast interface.
  Journal of reproductive immunology 1998 Giudice LC, Mark SP, Irwin JC
• Medical management of interstitial ectopic pregnancy: a case report and literature review.
  Human reproduction (Oxford, England) 1998 Fisch JD, Ortiz BH, Tazuke SI, Chitkara U, Giudice LC
• Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.
  The Journal of clinical endocrinology and metabolism 1998 Azhar S, Tsai L, Medicherla S, Chandrasekher Y, Giudice L, Reaven E
• Status of current research on endometriosis.
  The Journal of reproductive medicine 1998 Giudice LC, Tazuke SI, Swiersz L
• Insulin-like growth factor binding protein-1 binds to placental cytotrophoblast alpha5beta1 integrin and inhibits cytotrophoblast invasion into decidualized endometrial stromal cultures.
  Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998 Irwin JC, Giudice LC
• Insulin-like growth factor binding protein-1: recent findings and new directions.
  Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997 Lee PD, Giudice LC, Conover CA, Powell DR
• Multifaceted roles for IGFBP-1 in human endometrium during implantation and pregnancy.
  Annals of the New York Academy of Sciences 1997 Giudice LC
• Developmental regulation of telomerase activity in human fetal tissues during gestation.
  Molecular human reproduction 1997 Ulaner GA, Giudice LC
• Programmed cell death in human ovary is a function of follicle and corpus luteum status.
  The Journal of clinical endocrinology and metabolism 1997 Yuan W, Giudice LC
• Insulin-like growth factors and insulin-like growth factor binding proteins in androgen-dominant ovarian follicles from testosterone-treated female-to-male trans-sexuals.
  Fertility and sterility 1997 Yap OW, van Dessel HJ, Chandrasekher YA, Fauser BC, Giudice LC
• Gestational age-dependent expression of insulin-like growth factor-binding protein-1 (IGFBP-1) phosphoisoforms in human extraembryonic cavities, maternal serum, and decidua suggests decidua as the primary source of IGFBP-1 in these fluids during early pregnancy.
  The Journal of clinical endocrinology and metabolism 1997 Martina NA, Kim E, Chitkara U, Wathen NC, Chard T, Giudice LC
• Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia.
  American journal of obstetrics and gynecology 1997 Giudice LC, Martina NA, Crystal RA, Tazuke S, Druzin M
• Laparoscopic management of a noncommunicating uterine horn in a patient with an acute abdomen.
  Surgical laparoscopy & endoscopy 1997 Amara DP, Nezhat F, Giudice L, Nezhat C
• Role of growth hormone in ovarian physiology and onset of puberty.
  Journal of the Society for Gynecologic Investigation 1997 Sharara FI, Giudice LC
• Growth factors and cytokines in endometrium, embryonic development, and maternal: embryonic interactions.
  Seminars in reproductive endocrinology 1996 Tazuke SI, Giudice LC
• Growth factors and polycystic ovarian syndrome.
  Seminars in reproductive endocrinology 1996 Giudice LC, Morales AJ, Yen SS
• Growth factors in normal ovarian follicle development.
  Seminars in reproductive endocrinology 1996 Giudice LC, Cataldo NA, van Dessel HJ, Yap OW, Chandrasekher YA
• Insulin-like growth factor binding proteins in peritoneal fluid of women with minimal and mild endometriosis.
  Human reproduction (Oxford, England) 1996 Taskin O, Giudice L, Mangal R, Dunn RC, Dsupin BA, Poindexter AN, Wiehle RD
• Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.
  The Journal of clinical endocrinology and metabolism 1996 Klein NA, Battaglia DE, Miller PB, Branigan EF, Giudice LC, Soules MR
• Polycystic ovary syndrome.
  Human reproduction (Oxford, England) 1996 Homburg R, Giudice LC, Chang RJ
• Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle.
  The Journal of clinical endocrinology and metabolism 1996 Thierry van Dessel HJ, Chandrasekher Y, Yap OW, Lee PD, Hintz RL, Faessen GH, Braat DD, Fauser BC, Giudice LC
• Insulin receptor mediates inhibitory effect of insulin, but not of insulin-like growth factor (IGF)-I, on IGF binding protein 1 (IGFBP-1) production in human granulosa cells.
  The Journal of clinical endocrinology and metabolism 1996 Poretsky L, Chandrasekher YA, Bai C, Liu HC, Rosenwaks Z, Giudice L
• Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase. Hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle.
  The Journal of clinical investigation 1996 Irwin JC, Kirk D, Gwatkin RB, Navre M, Cannon P, Giudice LC
• Different molecular and messenger ribonucleic acid forms of insulin-like growth factor-binding protein-3 in the pregnant baboon (Papio anubis).
  The Journal of endocrinology 1995 Gargosky SE, Giudice LC, Rosenfeld RG, Fazleabas AT
• Estrogen- but not androgen-dominant human ovarian follicular fluid contains an insulin-like growth factor binding protein-4 protease.
  The Journal of clinical endocrinology and metabolism 1995 Chandrasekher YA, Van Dessel HJ, Fauser BC, Giudice LC
• IGF binding protein-3 protease regulation: how sweet it is!
  The Journal of clinical endocrinology and metabolism 1995 Giudice LC
• Radiation-induced premature menopause: a misconception.
  International journal of radiation oncology, biology, physics 1995 Madsen BL, Giudice L, Donaldson SS
• Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth.
  The Journal of clinical endocrinology and metabolism 1995 Giudice LC, de Zegher F, Gargosky SE, Dsupin BA, de las Fuentes L, Crystal RA, Hintz RL, Rosenfeld RG
• Follicular fluid insulin-like growth factor-I and insulin-like growth factor-II concentrations vary as a function of day 3 serum follicle stimulating hormone.
  Human reproduction (Oxford, England) 1995 Seifer DB, Giudice LC, Dsupin BA, Haning RV, Frishman GN, Burger HG
• Ovulatory function in epilepsy.
  Epilepsia 1995 Cummings LN, Giudice L, Morrell MJ
• Growth factors in reproduction.
  Trends in endocrinology and metabolism: TEM 1995 Giudice LC, Saleh W
• Regulation of insulin-like growth factor-binding protein-4 in human endometrial stromal cell cultures: evidence for ligand-induced proteolysis.
  The Journal of clinical endocrinology and metabolism 1995 Irwin JC, Dsupin BA, Giudice LC
• The insulin-like growth factor system in normal and abnormal human ovarian follicle development.
  The American journal of medicine 1995 Giudice LC
• Circulating and ovarian IGF binding proteins: potential roles in normo-ovulatory cycles and in polycystic ovarian syndrome.
  Progress in growth factor research 1995 Giudice LC, van Dessel HJ, Cataldo NA, Chandrasekher YA, Yap OW, Fauser BC
• Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle.
  The Journal of clinical endocrinology and metabolism 1994 Zhou J, Dsupin BA, Giudice LC, Bondy CA
• Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) fragments and IGFBP-5 proteolytic activity in human seminal plasma: a comparison of normal and vasectomized patients.
  The Journal of clinical endocrinology and metabolism 1994 Lee KO, Oh Y, Giudice LC, Cohen P, Peehl DM, Rosenfeld RG
• Insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and proteolyzed IGFBP-3 in embryonic cavities in early human pregnancy: their potential relevance to maternal-embryonic and fetal interactions.
  The Journal of clinical endocrinology and metabolism 1994 Nonoshita LD, Wathen NC, Dsupin BA, Chard T, Giudice LC
• The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis.
  The Journal of clinical endocrinology and metabolism 1994 Giudice LC, Dsupin BA, Gargosky SE, Rosenfeld RG, Irwin JC
• Growth factors and decidualization in vitro.
  Annals of the New York Academy of Sciences 1994 Irwin JC, de las Fuentes L, Giudice LC
• Insulin-like growth factor-binding proteins in the human fetus: tissue-specific protein secretion, immunologic characterization, and gene expression.
  American journal of obstetrics and gynecology 1994 Pannier EM, Irwin JC, Giudice LC
• Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones.
  The Journal of clinical investigation 1994 Rodgers WH, Matrisian LM, Giudice LC, Dsupin B, Cannon P, Svitek C, Gorstein F, Osteen KG
• Adnexal torsion: color Doppler diagnosis and laparoscopic treatment.
  Fertility and sterility 1994 Gordon JD, Hopkins KL, Jeffrey RB, Giudice LC
• Growth factors and growth modulators in human uterine endometrium: their potential relevance to reproductive medicine.
  Fertility and sterility 1994 Giudice LC
• Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata.
  Human reproduction (Oxford, England) 1993 Giudice LC, Irwin JC, Dsupin BA, Pannier EM, Jin IH, Vu TH, Hoffman AR
• Insulin-like growth factor regulation of human endometrial stromal cell function: coordinate effects on insulin-like growth factor binding protein-1, cell proliferation and prolactin secretion.
  Regulatory peptides 1993 Irwin JC, de las Fuentes L, Dsupin BA, Giudice LC
• Ethics of fetal tissue transplantation.
  The Western journal of medicine 1993 Sanders LM, Giudice L, Raffin TA
• The potential roles of intraovarian peptides in normal and abnormal mechanisms of reproductive physiology.
  Current opinion in obstetrics & gynecology 1993 Giudice LC, Chandrasekher YA, Cataldo NA
• Differential expression of messenger ribonucleic acids encoding insulin-like growth factors and their receptors in human uterine endometrium and decidua.
  The Journal of clinical endocrinology and metabolism 1993 Giudice LC, Dsupin BA, Jin IH, Vu TH, Hoffman AR
• Insulin-like growth factor binding proteins in sera of pregnant nonhuman primates.
  Endocrinology 1993 Giudice LC, Dsupin BA, de las Fuentes L, Gargosky SE, Rosenfeld RG, Zelinski-Wooten MB, Stouffer RL, Fazleabas AT
• Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo.
  Growth regulation 1993 Lamson G, Giudice LC, Cohen P, Liu F, Gargosky S, Müller HL, Oh Y, Wilson KF, Hintz RL, Rosenfeld RG
• Comparison of functional response of rat, macaque, and human ovarian cells in hormonally defined medium.
  Biology of reproduction 1993 Woodruff TK, Battaglia J, Bowdidge A, Molskness TA, Stouffer RL, Cataldo NA, Giudice LC, Orly J, Mather JP
• Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle.
  American journal of obstetrics and gynecology 1993 Rodgers WH, Osteen KG, Matrisian LM, Navre M, Giudice LC, Gorstein F
• Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium.
  The Journal of clinical endocrinology and metabolism 1993 Cataldo NA, Woodruff TK, Giudice LC
• Local anesthesia with conscious sedation for laparoscopic intrafallopian transfer.
  Fertility and sterility 1992 Milki AA, Hardy RI, el Danasouri I, Giudice LC, Lamb EJ
• Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting.
  Endocrinology 1992 Gargosky SE, Pham HM, Wilson KF, Liu F, Giudice LC, Rosenfeld RG
• Insulin-like growth factors and ovarian follicular development.
  Endocrine reviews 1992 Giudice LC
• Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation.
  The Journal of clinical endocrinology and metabolism 1992 Giudice LC, Dsupin BA, Irwin JC
• Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.
  The Journal of clinical endocrinology and metabolism 1992 Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG
• Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status.
  The Journal of clinical endocrinology and metabolism 1992 Cataldo NA, Giudice LC
• Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome.
  The Journal of clinical endocrinology and metabolism 1992 Cataldo NA, Giudice LC
• Identification of insulin-like growth factor binding proteins in human oviduct.
  Fertility and sterility 1992 Giudice LC, Dsupin BA, Irwin JC, Eckert RL
• Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy.
  Endocrinology 1991 Donovan SM, Giudice LC, Murphy LJ, Hintz RL, Rosenfeld RG
• Human granulosa contain messenger ribonucleic acids encoding insulin-like growth factor-binding proteins (IGFBPs) and secrete IGFBPs in culture.
  Fertility and sterility 1991 Giudice LC, Milki AA, Milkowski DA, el Danasouri I
• A simple assay for proteolysis of IGFBP-3.
  The Journal of clinical endocrinology and metabolism 1991 Lamson G, Giudice LC, Rosenfeld RG
• Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal cells.
  Human reproduction (Oxford, England) 1991 Giudice LC, Milkowski DA, Fielder PJ, Irwin JC
• Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis.
  The Journal of clinical endocrinology and metabolism 1991 Giudice LC, Milkowski DA, Lamson G, Rosenfeld RG, Irwin JC
• Clinical aspects of insulin-like growth factor binding proteins.
  Acta endocrinologica 1991 Cohen P, Fielder PJ, Hasegawa Y, Frisch H, Giudice LC, Rosenfeld RG
• Insulin-like growth factor binding proteins: structural and molecular relationships.
  Growth factors (Chur, Switzerland) 1991 Lamson G, Giudice LC, Rosenfeld RG
• Insulin-like growth factor-II (IGF-II) and IGF binding proteins in human endometrium.
  Annals of the New York Academy of Sciences 1991 Giudice LC, Lamson G, Rosenfeld RG, Irwin JC
• Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) and IGFBP-2 in human follicular fluid.
  The Journal of clinical endocrinology and metabolism 1990 Giudice LC, Farrell EM, Pham H, Rosenfeld RG
• Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity.
  The Journal of clinical endocrinology and metabolism 1990 Giudice LC, Farrell EM, Pham H, Lamson G, Rosenfeld RG
• Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma.
  The Journal of clinical endocrinology and metabolism 1990 Rosenfeld RG, Pham H, Oh Y, Lamson G, Giudice LC
• Insulinlike growth factor-binding proteins.
  Recent progress in hormone research 1990 Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L
• Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization.
  The Journal of clinical endocrinology and metabolism 1989 Lamson G, Oh Y, Pham H, Giudice LC, Rosenfeld RG
• Cryopreservation of embryos and ova.
  Fertility and sterility 1988 Friedler S, Giudice LC, Lamb EJ
• Angiographic arterial embolization to control hemorrhage in abdominal pregnancy: a case report.
  Obstetrics and gynecology 1988 Kivikoski AI, Martin C, Weyman P, Picus D, Giudice L
• Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman.
  Fertility and sterility 1987 Sauer MV, Macaso TM, Ishida EH, Giudice L, Marshall JR, Buster JE
• Clinical results of Stanford University's in vitro fertilization and embryo transfer program.
  Journal of in vitro fertilization and embryo transfer : IVF 1987 Lamb EJ, Polansky F, Milki A, Giudice LC, Friedler S, Wu T, Shen E, Turner K, Ho L
• Serum levels of CA-125 in patients with endometriosis: a preliminary report.
  Fertility and sterility 1986 Giudice LC, Jacobs A, Pineda J, Bell CE, Lippmann L
• The function of the common subunit of glycoprotein hormones.
  Biochemical Society transactions 1978 Pierce JG, Bloomfield GA, Giudice LC
• Separation of functional and non-functional beta subunits of thyrotropin preparations by polyacrylamide gel electrophoresis.
  Endocrinology 1977 Giudice LC, Pierce JG
• Studies on the disulfide bonds of glycoprotein hormones. Complete reduction and reoxidation of the disulfide bonds of the alpha subunit of bovine luteinizing hormone.
  The Journal of biological chemistry 1976 Giudice LC, Pierce JG
• Studies on the disulfide bonds of glycoprotein hormones. Course of reduction of bovine luteinizing hormone, bovine thyroid-stimulating hormone, and their subunits.
  The Journal of biological chemistry 1976 Pierce JG, Giudice LC, Reeve JR
• Structure and structure-function relationships in glycoprotein hormones.
  Ciba Foundation symposium 1976 Pierce JG, Faith MR, Giudice LC, Reeve JR