Lillian Brown, MD, PhD
Volunteer Assistant Clinical Professor
Medicine
School of Medicine

My research focuses on improving clinical outcomes among HIV-infected youth in sub-Saharan Africa and to study social network-informed approaches to support engagement in HIV care and improve HIV treatment outcomes.

Awards

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• Teri Liegler Young Scientist Career Award, UCSF, 2019
• Center for AIDS Research Excellence in Behavioral Research, UCSF, 2018

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2019
• Residency Medicine University of California San Francisco 2014
• Internship Medicine University of California San Francisco 2013
• M.D. School of Medicine University of North Carolina 2012
• PhD School of Public Health, Epidemiology University of North Carolina 2010
• BA Biology Harvard University 2001
• Fellowship Infectious Diseases University of California San Francisco

Grants and Projects

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• Leveraging Social Networks to Improve Retention in Care and Viral Suppression Among HIV-infected Youth in East Africa, NIH, 2018-2023
• A Randomized Trial of HIV Partner Notification in Malawi, NIH, 2008-2012

Publications (36)

Top publication keywords:
Health Services AdministrationMedication AdherenceSexual PartnersRural PopulationDiagnostic Tests, RoutineHIV InfectionsUgandaMalawiSocial NetworkingContact TracingAntibodies, NeutralizingKenyaGentamicinsDrug Resistance, MicrobialAnti-HIV Agents

• Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons.
  The New England journal of medicine 2024 Kelley CF, Acevedo-Quiñones M, Agwu AL, Avihingsanon A, Benson P, Blumenthal J, Brinson C, Brites C, Cahn P, Cantos VD, Clark J, Clement M, Creticos C, Crofoot G, Diaz RS, Doblecki-Lewis S, Gallardo-…
• SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV.
  AIDS (London, England) 2021 Spinelli MA, Brown LB, Glidden DV, Hunter K, Martin-Tuite P, Zheng J, Sera C, Havlir D, Buchbinder SP, Gandhi M
• Costs of integrating hypertension care into HIV care in rural East African clinics.
  AIDS (London, England) 2021 Shade SB, Osmand T, Kwarisiima D, Brown LB, Luo A, Mwebaza B, Mwesigye AR, Kwizera E, Imukeka H, Mwanga F, Ayieko J, Owaraganise A, Bukusi EA, Cohen CR, Charlebois ED, Black D, Clark TD, Petersen ML, …
• SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study.
  The lancet. HIV 2021 Spinelli MA, Lynch KL, Yun C, Glidden DV, Peluso MJ, Henrich TJ, Gandhi M, Brown LB
• HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda.
  PLoS medicine 2021 Koss CA, Havlir DV, Ayieko J, Kwarisiima D, Kabami J, Chamie G, Atukunda M, Mwinike Y, Mwangwa F, Owaraganise A, Peng J, Olilo W, Snyman K, Awuonda B, Clark TD, Black D, Nugent J, Brown LB, Marquez C,…

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• The interplay between HIV and COVID-19: summary of the data and responses to date.
  Current opinion in HIV and AIDS 2021 Brown LB, Spinelli MA, Gandhi M
• 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital.
  Open Forum Infectious Diseases 2020 Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio …
• 496. Higher SARS-CoV-2 RT-PCR Cycle Threshold (Ct) Values Associated with Longer Symptom Duration Among Patients Hospitalized with COVID-19.
  Open Forum Infectious Diseases 2020 Lillian B Brown, Lisa Gail Winston, Barbara Haller, Phong Pham, Beatrice Marcelo, Wendy Cheung, Kara Lynch, Vivek Jain
• Management and Outcomes of Critically-III Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series.
  medRxiv : the preprint server for health sciences 2020 Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, …
• Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study.
  The lancet. HIV 2020 Koss CA, Charlebois ED, Ayieko J, Kwarisiima D, Kabami J, Balzer LB, Atukunda M, Mwangwa F, Peng J, Mwinike Y, Owaraganise A, Chamie G, Jain V, Sang N, Olilo W, Brown LB, Marquez C, Zhang K, Ruel TD, …
• The Influence of Social Networks on Antiretroviral Therapy Initiation Among HIV-Infected Antiretroviral Therapy-Naive Youth in Rural Kenya and Uganda.
  Journal of acquired immune deficiency syndromes (1999) 2020 Brown LB, Balzer LB, Kabami J, Kwarisiima D, Sang N, Ayieko J, Chen Y, Chamie G, Charlebois ED, Camlin CS, Cohen CR, Bukusi E, Kamya MR, Moody J, Havlir DV, Petersen ML
• Hypertension control in integrated HIV and chronic disease clinics in Uganda in the SEARCH study.
  BMC public health 2019 Kwarisiima D, Atukunda M, Owaraganise A, Chamie G, Clark T, Kabami J, Jain V, Byonanebye D, Mwangwa F, Balzer LB, Charlebois E, Kamya MR, Petersen M, Havlir DV, Brown LB
• A Patient-Centered Multicomponent Strategy for Accelerated Linkage to Care Following Community-Wide HIV Testing in Rural Uganda and Kenya.
  Journal of acquired immune deficiency syndromes (1999) 2019 Ayieko J, Petersen ML, Charlebois ED, Brown LB, Clark TD, Kwarisiima D, Kamya MR, Cohen CR, Bukusi EA, Havlir DV, Van Rie A
• Factors predictive of successful retention in care among HIV-infected men in a universal test-and-treat setting in Uganda and Kenya: A mixed methods analysis.
  PloS one 2019 Brown LB, Getahun M, Ayieko J, Kwarisiima D, Owaraganise A, Atukunda M, Olilo W, Clark T, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, Havlir DV, Camlin CS
• A patient-centered multi-component strategy for accelerated linkage to care following community-wide HIV testing in rural Uganda and Kenya.
  Journal of acquired immune deficiency syndromes (1999) 2018 Ayieko J, Petersen ML, Charlebois ED, Brown LB, Clark TD, Kwarisiima D, Kamya MR, Cohen CR, Bukusi EA, Havlir DV, Van Rie A
• Costs of streamlined HIV care delivery in rural Ugandan and Kenyan clinics in the SEARCH Studys.
  AIDS (London, England) 2018 Shade SB, Osmand T, Luo A, Aine R, Assurah E, Mwebaza B, Mwai D, Owaraganise A, Mwangwa F, Ayieko J, Black D, Brown LB, Clark TD, Kwarisiima D, Thirumurthy H, Cohen CR, Bukusi EA, Charlebois ED, …
• "Hurdles on the path to 90-90-90 and beyond": Qualitative analysis of barriers to engagement in HIV care among individuals in rural East Africa in the context of test-and-treat.
  PloS one 2018 Ayieko J, Brown L, Anthierens S, Van Rie A, Getahun M, Charlebois ED, Petersen ML, Clark TD, Kamya MR, Cohen CR, Bukusi EA, Havlir DV, Camlin CS
• Predictors of Retention in HIV Care Among Youth (15-24) in a Universal Test-and-Treat Setting in Rural Kenya.
  Journal of acquired immune deficiency syndromes (1999) 2017 Brown LB, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Jain V, Ruel T, Clark T, Black D, Chamie G, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, Havlir DV
• High levels of retention in care with streamlined care and universal test and treat in East Africa.
  AIDS (London, England) 2016 Brown LB, Havlir DV, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Jain V, Ruel T, Clark T, Chamie G, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, SEARCH Collaboration
• Antimicrobial Resistance: A Call to Action!
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Brown L, Langelier C, Reid MJ, Rutishauser RL, Strnad L
• Maximizing HIV partner notification opportunities for index patients and their sexual partners in Malawi.
  Malawi medical journal : the journal of Medical Association of Malawi 2015 Kamanga G, Brown L, Jawati P, Chiwanda D, Nyirenda N
• The feasibility of an intensive case management program for injection drug users on antiretroviral therapy in St. Petersburg, Russia.
  Harm reduction journal 2013 Shaboltas AV, Skochilov RV, Brown LB, Elharrar VN, Kozlov AP, Hoffman IF
• Cost-effectiveness of provider-based HIV partner notification in urban Malawi.
  Health policy and planning 2013 Rutstein SE, Brown LB, Biddle AK, Wheeler SB, Kamanga G, Mmodzi P, Nyirenda N, Mofolo I, Rosenberg NE, Hoffman IF, Miller WC
• Point-of-Care Diagnostics for Acute HIV Infection: An Important Public Health Priority.
  The Journal of Infectious Diseases 2012 Nora E. Rosenberg, Gift Kamanga, Sam Phiri, Dominic Nsona, Audrey Pettifor, Sarah E. Rutstein, Deborah Kamwendo, Irving F. Hoffman, Maria Keating, Lillian B. Brown, Beatrice Ndalama, Susan A. Fiscus, …
• Predicting partner HIV testing and counseling following a partner notification intervention.
  AIDS and behavior 2012 Brown LB, Miller WC, Kamanga G, Kaufman JS, Pettifor A, Dominik RC, Nyirenda N, Mmodzi P, Mapanje C, Martinson F, Cohen MS, Hoffman IF
• Detection of acute HIV infection: a field evaluation of the determine® HIV-1/2 Ag/Ab combo test.
  The Journal of infectious diseases 2011 Rosenberg NE, Kamanga G, Phiri S, Nsona D, Pettifor A, Rutstein SE, Kamwendo D, Hoffman IF, Keating M, Brown LB, Ndalama B, Fiscus SA, Congdon S, Cohen MS, Miller WC
• HIV partner notification is effective and feasible in sub-Saharan Africa: opportunities for HIV treatment and prevention.
  Journal of acquired immune deficiency syndromes (1999) 2011 Brown LB, Miller WC, Kamanga G, Nyirenda N, Mmodzi P, Pettifor A, Dominik RC, Kaufman JS, Mapanje C, Martinson F, Cohen MS, Hoffman IF
• Viewpoint: Gentamicin for treatment of gonococcal urethritis in Malawi.
  Malawi medical journal : the journal of Medical Association of Malawi 2010 Kamanga G, Mhango C, Brown L
• Accelerating worldwide syphilis screening through rapid testing: a systematic review.
  The Lancet. Infectious diseases 2010 Tucker JD, Bu J, Brown LB, Yin YP, Chen XS, Cohen MS
• Second-line treatment in the Malawi antiretroviral programme: high early mortality, but good outcomes in survivors, despite extensive drug resistance at baseline.
  HIV medicine 2010 Hosseinipour MC, Kumwenda JJ, Weigel R, Brown LB, Mzinganjira D, Mhango B, Eron JJ, Phiri S, van Oosterhout JJ
• Neisseria gonorrhoeae antimicrobial susceptibility in Lilongwe, Malawi, 2007.
  Sexually transmitted diseases 2010 Brown LB, Krysiak R, Kamanga G, Mapanje C, Kanyamula H, Banda B, Mhango C, Hoffman M, Kamwendo D, Hobbs M, Hosseinipour MC, Martinson F, Cohen MS, Hoffman IF
• Epidemiology of injuries at a tertiary care center in Malawi.
  World journal of surgery 2009 Samuel JC, Akinkuotu A, Villaveces A, Charles AG, Lee CN, Hoffman IF, Miller WC, Baloyi P, Hoffman M, Brown LB, Muyco AP
• Diagnosis of antiretroviral therapy failure in Malawi: poor performance of clinical and immunological WHO criteria.
  Tropical medicine & international health : TM & IH 2009 van Oosterhout JJ, Brown L, Weigel R, Kumwenda JJ, Mzinganjira D, Saukila N, Mhango B, Hartung T, Phiri S, Hosseinipour MC
• Morbidity and mortality among a cohort of human immunodeficiency virus type 1-infected and uninfected pregnant women and their infants from Malawi, Zambia, and Tanzania.
  The Pediatric infectious disease journal 2008 Chilongozi D, Wang L, Brown L, Taha T, Valentine M, Emel L, Sinkala M, Kafulafula G, Noor RA, Read JS, Brown ER, Goldenberg RL, Hoffman I, HIVNET 024 Study Team
• Genetic and environmental influences on bone mineral density in pre- and post-menopausal women.
  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2005 Brown LB, Streeten EA, Shapiro JR, McBride D, Shuldiner AR, Peyser PA, Mitchell BD
• Assessment of sex-specific genetic and environmental effects on bone mineral density.
  Genetic epidemiology 2004 Brown LB, Streeten EA, Shuldiner AR, Almasy LA, Peyser PA, Mitchell BD