Lianne Gensler, MD
Professor
Medicine
School of Medicine
lianne.gensler@ucsf.edu 415-353-2497
Dr. Lianne Gensler is a rheumatologist and serves as director of the UCSF Ankylosing Spondylitis Clinic, which is dedicated to care for this inflammatory disease.
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Gensler's primary research interest is the disease progression of axial spondyloarthritis (a category that includes ankylosing spondylitis). Her research also seeks to identify predictors of osteoporosis development in patients with systemic lupus erythematosus.
Gensler earned her medical degree at the University of California, Irvine. She completed an internal medicine residency, chief residency and rheumatology fellowship at UCSF, and subsequently joined the medical staff in the rheumatology program.
Awards
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- Ira M. Goldstein Teaching award in Rheumatology, University of California, San Francisco, 2015
- Research Mentoring Award, University of California, San Francisco, 2015
- Spondylitis Association Young Investigator Award, 2012
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2019
- Certificate Medicine (Advance Training in Clinical Research) University of California, San Francisco 2008
- Rheumatology Fellowship University of California, San Francisco 2008
- Chief Resident University of California, San Francisco 2005
- Residency, Internal Medicine University of California, San Francisco 2004
- M.D. School of Medicine University of California Irvine 2001
- B.S. Microbiology & Molecular Genetics University of California, Los Angeles 1995
Interests
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- outcomes
- Axial Spondyloarthritis
- Ankylosing Spondylitis
- biomarkers
- Spondyloarthritis
Websites
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- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
Publications (243)
Top publication keywords:
Antibodies, Monoclonal, HumanizedSpondylitis, AnkylosingArthritis, PsoriaticAnti-Inflammatory Agents, Non-SteroidalUstekinumabSpondylitisRheumatologySacroiliitisNetwork Meta-AnalysisAntirheumatic AgentsCertolizumab PegolHLA-B27 AntigenEnthesopathySpondylarthritisTherapies, Investigational
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Sex-related differences in efficacy and safety outcomes in axial spondyloarthritis randomized clinical trials: A systematic literature review and meta-analysis.
Arthritis care & research 2025 Gao A, Pardo JP, Dang S, Gensler LS, Mease P, Eder L -
The Assessment of SpondyloArthritis International Society (ASAS) Consensus-Based Expert Definition of Difficult-to-Manage, including Treatment-Refractory, Axial Spondyloarthritis.
Annals of the rheumatic diseases 2025 Poddubnyy D, Navarro-Compán V, Torgutalp M, Arends S, Aydin SZ, Battista S, van den Bosch F, Bundy C, Cauli A, Davies J, Dougados M, Duruöz T, El-Zorkany B, Fong W, van Gaalen F, Garcia-Salinas R, … -
1995-2025: thirty years of ASAS and its contribution to the understanding of spondyloarthritis.
Annals of the rheumatic diseases 2025 van der Heijde D, Navarro-Compán V, Landewé R, Sieper J, van Gaalen F, Gensler LS, Machado PM, Marzo-Ortega H, Poddubnyy D, Protopopov M, Ramiro S, Sepriano A, Baraliakos X -
Long-term safety and sustained efficacy of bimekizumab in patients with ankylosing spondylitis (radiographic axial spondyloarthritis): 5-year results from BE AGILE (phase 2b) and its open-label extension.
RMD open 2025 Deodhar A, Navarro-Compán V, Poddubnyy D, Gensler LS, Ramiro S, Tomita T, Marzo-Ortega H, Fleurinck C, Vaux T, Massow U, de Peyrecave N, van der Heijde D, Baraliakos X -
Long-Term Safety and Efficacy of Bimekizumab in Axial Spondyloarthritis: 2-Year Results from Two Phase 3 Studies.
Rheumatology (Oxford, England) 2025 Baraliakos X, Deodhar A, van der Heijde D, Van den Bosch F, Magrey M, Maksymowych WP, Tomita T, Xu H, Massow U, Vaux T, Prajapati C, Manente M, Marten A, Gensler LS
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Radiographic Axial Spondyloarthritis (Ankylosing Spondylitis) Commencing Late in Life.
The Journal of rheumatology 2025 Hwang MC, Doughem K, Lee M, Gensler LS, Ishimori ML, Ward MM, Brown MA, Tahanan A, Weisman MH, Rahbar MH, Reveille JD -
Faible taux d’uvéites chez les patients atteints de spondyloarthrite axiale ou de rhumatisme psoriasique traités par bimekizumab : résultats à long terme des essais de phase IIb/III.
Revue du Rhumatisme 2024 C. Miceli Richard, I.E. Van Der Horst-Bruinsma, M.A. Brown, F.A. Van Gaalen, N. Haroon, L.S. Gensler, A. Marten, M. Manente, G. Stojan, T. Vaux, K. White, A. Deodhar, M. Rudwaleit -
Le traitement par bimekizumab a été efficace à 2ans, quelle que soit la durée des symptômes de l’axSpA : résultats de deux essais de phase III.
Revue du Rhumatisme 2024 S. Ramiro, F. Proft, R. Sengupta, A. Van Tubergen, A. Molto, L.S. Gensler, M. Kishimoto, V. Taieb, D. Voiniciuc, U. Massow, V. Navarro-Compán -
Mise à jour de la tolérance à long terme du bimekizumab chez les patients atteints de spondylarthrite axiale (axSpA) et de rhumatisme psoriasique (RhuPso) : résultats regroupés des études de phase IIb/III.
Revue du Rhumatisme 2024 M. Breban, P.J. Mease, D. Poddubnyy, R. Bajracharya, B. Ink, A. Marten, U. Massow, V. Shende, M. Manente, L. Peterson, K. White, P. Nash, L.S. Gensler -
Prologue: Spondyloarthritis Unmet Research Needs Conference IV.
The Journal of rheumatology 2024 Colbert RA, Carroll E, Dubreuil M, Gensler LS, Haroon N, Howard R, Ogdie AR, Shafer C, Weiss PF, Kuhn KA -
Unmet Needs in Spondyloarthritis: Imaging in Axial Spondyloarthritis.
The Journal of rheumatology 2024 Gensler LS, Jans L, Majumdar S, Poddubnyy D -
Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials.
Annals of the rheumatic diseases 2024 Brown MA, Rudwaleit M, van Gaalen FA, Haroon N, Gensler LS, Fleurinck C, Marten A, Massow U, de Peyrecave N, Vaux T, White K, Deodhar A, van der Horst-Bruinsma I -
Comment on: Effect of gender and age on bDMARD efficacy for axial spondyloarthritis patients: a meta-analysis of randomized controlled trials.
Rheumatology (Oxford, England) 2024 Eder L, Pardo JP, Mease P, Gensler LS -
The mSQUASH is a feasible and valid measurement tool to uniformly assess daily physical activity in patients with rheumatic diseases.
RMD open 2024 van der Kraan YM, Gensler L, Paap D, Thovmasyan E, Ausma N, Kokol H, Carbo M, Kieskamp SC, de Leeuw K, van der Geest KSM, Bootsma H, Spoorenberg A, Arends S -
Low Socioeconomic Status and Female Sex are Associated With Worse Functional Status in Axial Spondyloarthritis.
Arthritis care & research 2024 Stovall R, Li J, Fitzpatrick J, Roberts E, Palmowski A, Anastasiou C, Izadi Z, Friedly J, Singh N, Gensler LS, Schmajuk G, Yazdany J -
ASAS consensus definition of early axial spondyloarthritis.
Annals of the rheumatic diseases 2024 Navarro-Compán V, Benavent D, Capelusnik D, van der Heijde D, Landewé RB, Poddubnyy D, van Tubergen A, Baraliakos X, Van den Bosch FE, van Gaalen FA, Gensler L, López-Medina C, Marzo-Ortega H, Molto A… -
A secukinumab dose-escalation study in patients with ankylosing spondylitis not achieving inactive disease after 16 weeks of treatment.
Rheumatology (Oxford, England) 2024 Deodhar A, Kivitz AJ, Magrey M, Walsh JA, Mease PJ, Greenwald M, Kianifard F, Elam C, Bommidi GM, Winseck A, Gensler LS -
Efficacy and Safety of Tofacitinib in Ankylosing Spondylitis by Baseline C-Reactive Protein Level: Post Hoc Analysis of Phase II and Phase III Clinical Trials.
The Journal of rheumatology 2024 Deodhar A, Baraliakos X, Magrey M, Gensler LS, Thorat AV, Pemmaraju SK, Cadatal MJ, Nash P -
Pregnancy Outcomes in Patients Treated with Upadacitinib: Analysis of Data from Clinical Trials and Postmarketing Reports.
Drug safety 2024 Mahadevan U, Levy G, Gensler L, Ali M, Lacerda AP, Wegrzyn L, Palac H, Bhutani-Jacques T, Long M, Clowse MEB, Kimball AB, Chambers C, Scialli AR -
Improved physical functioning, sleep, work productivity and overall health-related quality of life with bimekizumab in patients with axial spondyloarthritis: results from two phase 3 studies.
RMD open 2024 Dubreuil M, Navarro-Compán V, Boonen A, Gaffney K, Gensler LS, de la Loge C, Vaux T, Fleurinck C, Massow U, Taieb V, Mørup MF, Deodhar A, Rudwaleit M -
The association of TNF inhibitor use with incident cardiovascular events in radiographic axial spondyloarthritis.
Seminars in arthritis and rheumatism 2024 Liew JW, Treu T, Park Y, Ferguson JM, Rosser MA, Ho YL, Gagnon DR, Stovall R, Monach P, Heckbert SR, Gensler LS, Liao KP, Dubreuil M -
AB0881 LONG-TERM SAFETY AND TOLERABILITY OF BIMEKIZUMAB IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS AND PSORIATIC ARTHRITIS: RESULTS FROM POOLED PHASE 2B/3 STUDIES.
Annals of the Rheumatic Diseases 2024 P.J. Mease, D. Poddubnyy, A.M. Orbai, R.B. Warren, C. Fleurinck, R. Bajracharya, B. Ink, U. Massow, V. Shende, J. Shepherd-Smith, L. Peterson, K. White, R. Landewé, L.S. Gensler -
AB0913 EFFICACY OF CERTOLIZUMAB PEGOL IN PREVENTING ANTERIOR UVEITIS FLARES COMPARED WITH STANDARD NON-BIOLOGIC TREATMENT: A MATCHED CONTROL STUDY IN HIGH-RISK PATIENTS WITH AXIAL SPONDYLOARTHRITIS.
Annals of the Rheumatic Diseases 2024 N. Haroon, Z. Baskurt, T. Chim, R. Inman, D. Paez, T. Kumke, R. Tham, M. Kim, I. Van der Horst-Bruinsma, L.S. Gensler -
POS0194 FACTORS ASSOCIATED WITH RADIOGRAPHIC SPINAL PROGRESSION IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS RECEIVING IL-17A INHIBITOR OR TNF INHIBITOR THERAPY: A POST-HOC ANALYSIS OF THE SURPASS STUDY.
Annals of the Rheumatic Diseases 2024 D. Poddubnyy, J. Braun, P. Machado, V. Navarro-Compán, L.S. Gensler, K.G. Hermann, E. Quebe-Fehling, C.C. Pieterse, A. Readie, C. Gaillez, X. Baraliakos -
POS0215 LONG-TERM SAFETY AND EFFICACY OF BIMEKIZUMAB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: 5-YEAR RESULTS FROM A PHASE 2B STUDY AND ITS OPEN-LABEL EXTENSION.
Annals of the Rheumatic Diseases 2024 A. Deodhar, V. Navarro-Compán, D. Poddubnyy, L.S. Gensler, S. Ramiro, T. Tomita, H. Marzo-Ortega, C. Fleurinck, T. Vaux, U. Massow, D. Van der Heijde, X. Baraliakos -
POS0391 THE MSQUASH AS MEASUREMENT TOOL FOR DAILY PHYSICAL ACTIVITY: TRANSLATION AND CROSS-CULTURAL ADAPTATION INTO ENGLISH, FIELD-TESTING IN DIFFERENT RHEUMATIC DISEASES AND CLINICAL VALIDATION IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS.
Annals of the Rheumatic Diseases 2024 Y.M. Van der Kraan, L.S. Gensler, D. Paap, E. Thovmasyan, N.S. Ausma, H. Kokol, M. Carbo, K. De Leeuw, K. Van der Geest, H. Bootsma, J.P.L. Spoorenberg, S. Arends -
POS0806 LONG-TERM SUSTAINED EFFICACY AND SAFETY OF BIMEKIZUMAB ACROSS THE FULL SPECTRUM OF AXIAL SPONDYLOARTHRITIS: 2-YEAR RESULTS FROM TWO PHASE 3 STUDIES.
Annals of the Rheumatic Diseases 2024 X. Baraliakos, A. Deodhar, D. Van der Heijde, F. Van den Bosch, M. Magrey, W.P. Maksymowych, T. Tomita, H. Xu, U. Massow, C. Fleurinck, T. Vaux, C. Prajapati, J. Shepherd-Smith, A. Marten, L.S. … -
Long-term clinical outcomes of certolizumab pegol treatment in non-radiographic axial spondyloarthritis stratified by baseline MRI and CRP status.
RMD open 2024 Rudwaleit M, Deodhar A, Bauer L, Gensler L, Hoepken B, Kumke T, Auteri SE, Kim M, Maksymowych W -
Comparative efficacy and safety of bimekizumab in axial spondyloarthritis: a systematic literature review and network meta-analysis.
Rheumatology (Oxford, England) 2024 Deodhar A, Machado PM, Mørup M, Taieb V, Willems D, Orme M, Pritchett D, Gensler LS -
Effect of Secukinumab Versus Adalimumab Biosimilar on Radiographic Progression in Patients With Radiographic Axial Spondyloarthritis: Results From a Head-to-Head Randomized Phase IIIb Study.
Arthritis & rheumatology (Hoboken, N.J.) 2024 Baraliakos X, Østergaard M, Poddubnyy D, van der Heijde D, Deodhar A, Machado PM, Navarro-Compán V, Hermann KGA, Kishimoto M, Lee EY, Gensler LS, Kiltz U, Eigenmann MF, Pertel P, Readie A, Richards HB… -
Safety Profile of Upadacitinib up to 5 Years in Psoriatic Arthritis, Ankylosing Spondylitis, and Non-radiographic Axial Spondyloarthritis: An Integrated Analysis of Clinical Trials.
Rheumatology and therapy 2024 Burmester GR, Stigler J, Rubbert-Roth A, Tanaka Y, Azevedo VF, Coombs D, Lagunes I, Lippe R, Wung P, Gensler LS -
P163 Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials.
Rheumatology 2024 Martin Rudwaleit, Matthew A Brown, Floris Alexander van Gaalen, Nigil Haroon, Lianne S Gensler, Carmen Fleurinck, Alexander Marten, Ute Massow, Natasha de Peyrecave, Thomas Vaux, Katy White, Atul … -
Goodbye to the term 'ankylosing spondylitis', hello 'axial spondyloarthritis': time to embrace the ASAS-defined nomenclature.
Annals of the rheumatic diseases 2024 van der Heijde D, Molto A, Ramiro S, Braun J, Dougados M, van Gaalen FA, Gensler LS, Inman RD, Landewé RBM, Marzo-Ortega H, Navarro-Compán V, Phoka A, Poddubnyy D, Protopopov M, Reveille J, Rudwaleit … -
Bimekizumab treatment in patients with active axial spondyloarthritis: 52-week efficacy and safety from the randomised parallel phase 3 BE MOBILE 1 and BE MOBILE 2 studies.
Annals of the rheumatic diseases 2024 Baraliakos X, Deodhar A, van der Heijde D, Magrey M, Maksymowych WP, Tomita T, Xu H, Massow U, Fleurinck C, Ellis AM, Vaux T, Shepherd-Smith J, Marten A, Gensler LS -
Effet du sécukinumab versus adalimumab biosimilaire sur la progression radiographique chez les patients atteints de spondyloarthrite axiale radiographique : analyse en sous-groupes avec sur le statut syndesmophytes et protéine C-réactive à l’inclusion.
Revue du Rhumatisme 2023 C. Roux, D. Poddubnyy, D. Van Der Heijde, D. Atul, P. Machado, V. Navarro-compán, K.G. Hermann, M. Kishimoto, E.Y. Lee, L. Gensler, U. Kiltz, M. Eigenman, P. Pertel, A. Readie, H. Richards, B. Porter,… -
Effet du sécukinumab versus adalimumab biosimilaire sur la progression radiographique chez les patients atteints de spondyloarthrite axiale radiographique : étude randomisée de phase 3b.
Revue du Rhumatisme 2023 A. Constantin, X. Baraliakos, M. Østergaard, D. Poddubnyy, D. Van Der Heijde, D. Atul, P. Machado, V. Navarro-compán, K.G. Hermann, M. Kishimoto, E.Y. Lee, L. Gensler, U. Kiltz, M. Eigenman, P. Pertel… -
Faibles taux d’uvéites chez les patients atteints de spondyloarthrite axiale traités par bimékizumab : résultats regroupés des essais de phase IIb/III.
Revue du Rhumatisme 2023 M. Dougados, M. Rudwaleit, M.A. Brown, F.A. Van Gaalen, N. Haroon, L.S. Gensler, C. Fleurinck, A. Marten, U. Massow, N. De Peyrecave, T. Vaux, K. White, A. Deodhar, I.E. Van Der Horst-Bruinsma -
Structural disease modification in axial spondyloarthritis.
Best practice & research. Clinical rheumatology 2023 Dinneen B, O'Shea F, Gensler L -
Tolérance et efficacité à long terme du bimékizumab chez les patients atteints de spondylarthrite ankylosante active : résultats à 5 ans d’une étude de phase IIb et de son extension en ouvert.
Revue du Rhumatisme 2023 M. Dougados, A. Deodhar, V. Navarro-compán, D. Poddubnyy, L.S. Gensler, S. Ramiro, T. Tomita, H. Marzo-Ortega, C. Fleurinck, T. Vaux, U. Massow, D. Van Der Heijde, X. Baraliakos -
Tolérance à long terme du bimékizumab chez les patients atteints de spondyloarthrite axiale (axSpA) et de rhumatisme psoriasique (RhPso) : résultats groupés des études de phase IIb/III.
Revue du Rhumatisme 2023 M. Breban, P.J. Mease, D. Poddubnyy, A.M. Orbai, R.B. Warren, C. Fleurinck, R. Bajracharya, B. Ink, U. Massow, V. Shende, J. Sheperd-Smith, L. Peterson, K. White, R. Landewé, L.S. Gensler -
Multimorbidity phenotypes in ankylosing spondylitis and their association with disease activity and functional impairment: Data from the prospective study of outcomes in ankylosing spondylitis cohort.
Seminars in arthritis and rheumatism 2023 Karmacharya P, Crowson CS, Lennon RJ, Poudel D, Davis JM, Ogdie A, Liew JW, Ward MM, Ishimori M, Weisman MH, Brown MA, Rahbar MH, Hwang MC, Reveille JD, Gensler LS -
Incidence Rate and Factors Associated With Fractures Among Medicare Beneficiaries With Ankylosing Spondylitis in the United States.
Arthritis care & research 2023 Stovall R, Kersey E, Li J, Baker R, Anastasiou C, Palmowski A, Schmajuk G, Gensler L, Yazdany J -
Tofacitinib Efficacy and Safety in Patients With Ankylosing Spondylitis by Prior Biologic Disease-Modifying Antirheumatic Drug Use: A Post Hoc Analysis.
ACR open rheumatology 2023 Deodhar A, Marzo-Ortega H, Wu J, Wang C, Dina O, Kanik KS, Fallon L, Gensler LS -
44092 Tuberculid reactions at a US academic medical center: A retrospective review.
Journal of the American Academy of Dermatology 2023 Rebecca Jacobson, A. Gutierrez, Azan Z. Virji, Shilpa Ghatnekar, Brian Schwartz, Lianne S. Gensler, Anna Haemel -
44261 Cutaneous tuberculosis at a US academic medical center: A retrospective review.
Journal of the American Academy of Dermatology 2023 Rodrigo A. Gutierrez, Rebecca Jacobson, Azan Z. Virji, Shilpa Ghatnekar, Lianne S. Gensler, Brian Schwartz, Anna Haemel -
Achievement of higher thresholds of clinical responses and lower levels of disease activity is associated with improvements in workplace and household productivity in patients with axial spondyloarthritis.
Therapeutic advances in musculoskeletal disease 2023 Rudwaleit M, Machado PM, Taieb V, de Peyrecave N, Hoepken B, Gensler LS -
Tuberculid reactions: A multi-institution cohort study from 2 academic medical centers in the United States.
JAAD international 2023 Jacobson R, Gutierrez RA, Ghatnekar S, Virji AZ, Schwartz BS, Gensler LS, Haemel A, Frangos JE -
Cutaneous tuberculosis: A multi-institution cohort study from 2 academic medical centers in the United States.
JAAD international 2023 Gutierrez RA, Jacobson R, Ghatnekar S, Virji AZ, Schwartz BS, Gensler LS, Haemel A, Frangos JE -
Effect of Biologics in Subgroups of Axial Spondyloarthritis Based on Magnetic Resonance Imaging and C-Reactive Protein: A Systematic Review and Meta-Analysis.
ACR open rheumatology 2023 Karmacharya P, Gupta S, Shahukhal R, Khanal R, Murad MH, Gensler LS -
The association of psoriasis with rheumatic diseases: A national cross-sectional study.
Journal of the American Academy of Dermatology 2023 Chung M, Liu J, Yeroushalmi S, Bartholomew E, Hakimi M, Gensler LS, Bhutani T, Liao W -
POS0657 LONG-TERM SAFETY OF UPADACITINIB IN PSORIATIC ARTHRITIS, ANKYLOSING SPONDYLITIS, AND NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS UP TO 5 YEARS.
Annals of the Rheumatic Diseases 2023 G.R. Burmester, J. Stigler, A. Rubbert-Roth, Y. Tanaka, V.F. Azevedo, D. Coombs, R. Mccaskill, R. Lippe, P. Wung, L.S. Gensler -
SA50 Comparative Efficacy of Bimekizumab in Biologic/Targeted Synthetic DMARD-Naïve Patients with Axial Spondyloarthritis: Results from a Systematic Literature Review and Network Meta-Analysis.
Value in Health 2023 A. Deodhar, P.M Machado, M. Mørup, V. Taieb, D. Willems, M.E Orme, D. Stewart, L.S Gensler -
AB0937 TOFACITINIB EFFICACY AND SAFETY IN PATIENTS WITH ANKYLOSING SPONDYLITIS BY BASELINE C-REACTIVE PROTEIN LEVELS: A POST HOC ANALYSIS.
Annals of the Rheumatic Diseases 2023 A. Deodhar, X. Baraliakos, M. Magrey, L. S. Gensler, A. V. Thorat, C. Kinch, S. Pemmaraju, M. J. Cadatal, P. Nash -
AB0938 SAFETY PROFILE OF BIMEKIZUMAB AT WEEK 16 IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS AND PSORIATIC ARTHRITIS: RESULTS FROM FOUR PLACEBO-CONTROLLED PHASE 3 STUDIES.
Annals of the Rheumatic Diseases 2023 D. Poddubnyy, L. S. Gensler, P. J. Mease, A. M. Orbai, R. B. Warren, B. Ink, U. Massow, D. Assudani, C. Fleurinck, V. Shende, J. Smith, L. Peterson, K. White, R. B. M. Landewé -
OP0055 ASAS CONSENSUS DEFINITION OF EARLY AXIAL SPONDYLOARTHRITIS.
Annals of the Rheumatic Diseases 2023 V. Navarro-Compán, D. Benavent, D. Capelusnik, D. Van der Heijde, R. B. M. Landewé, D. Poddubnyy, A. Van Tubergen, X. Baraliakos, F. Van den Bosch, F. A. Van Gaalen, L. S. Gensler, C. López-Medina, H.… -
OP0059 EFFECT OF SECUKINUMAB VERSUS ADALIMUMAB BIOSIMILAR ON RADIOGRAPHIC PROGRESSION IN PATIENTS WITH RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: A RANDOMISED PHASE IIIB STUDY.
Annals of the Rheumatic Diseases 2023 X. Baraliakos, M. Østergaard, D. Poddubnyy, D. Van der Heijde, A. Deodhar, P. Machado, V. Navarro-Compán, K. G. Hermann, M. Kishimoto, E. Y. Lee, L. S. Gensler, U. Kiltz, M. Eigenmann, P. Pertel, A. … -
POS0665 INCIDENCE RATE AND FACTORS ASSOCIATED WITH FRACTURES AMONG ADULTS WITH ANKYLOSING SPONDYLITIS IN THE UNITED STATES.
Annals of the Rheumatic Diseases 2023 R. Stovall, E. Kersey, J. LI, R. Baker, C. Anastasiou, A. Palmowski, G. Schmajuk, L. S. Gensler, J. Yazdany -
POS0668 LOW UVEITIS RATES IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS TREATED WITH BIMEKIZUMAB: POOLED RESULTS FROM PHASE 2B/3 TRIALS.
Annals of the Rheumatic Diseases 2023 M. Rudwaleit, M. Brown, F. A. Van Gaalen, N. Haroon, L. S. Gensler, C. Fleurinck, A. Marten, U. Massow, N. De Peyrecave, T. Vaux, K. White, A. Deodhar, I. Van der Horst-Bruinsma -
POS0683 AN EXPLORATORY ANALYSIS OF THE POTENTIAL DISCONNECT BETWEEN OBJECTIVE INFLAMMATORY RESPONSE AND CLINICAL RESPONSE FOLLOWING CERTOLIZUMAB PEGOL TREATMENT IN PATIENTS WITH ACTIVE AXIAL SPONDYLOARTHRITIS.
Annals of the Rheumatic Diseases 2023 M. Rudwaleit, F. Van den Bosch, H. Marzo-Ortega, V. Navarro-Compán, R. Tham, T. Kumke, L. Bauer, M. Kim, L. S. Gensler -
POS1103 BIMEKIZUMAB MAINTAINED IMPROVEMENTS IN EFFICACY ENDPOINTS AND HAD A CONSISTENT SAFETY PROFILE THROUGH 52 WEEKS IN PATIENTS WITH NON-RADIOGRAPHIC AND RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: RESULTS FROM TWO PARALLEL PHASE 3 STUDIES.
Annals of the Rheumatic Diseases 2023 X. Baraliakos, A. Deodhar, D. Van der Heijde, M. Magrey, W. P. Maksymowych, T. Tomita, H. Xu, M. Oortgiesen, U. Massow, C. Fleurinck, A. Ellis, T. Vaux, J. Smith, A. Marten, L. S. Gensler -
POS1115 EFFECT OF SECUKINUMAB VERSUS ADALIMUMAB BIOSIMILAR ON RADIOGRAPHIC PROGRESSION IN PATIENTS WITH RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: SUBGROUP ANALYSES BY BASELINE SYNDESMOPHYTES AND C-REACTIVE PROTEIN STATUS.
Annals of the Rheumatic Diseases 2023 X. Baraliakos, D. Van der Heijde, P. Machado, V. Navarro-Compán, L. S. Gensler, P. Pertel, E. Quebe-Fehling, A. Readie, H. Richards, D. Poddubnyy -
Two-year imaging outcomes from a phase 3 randomized trial of secukinumab in patients with non-radiographic axial spondyloarthritis.
Arthritis research & therapy 2023 Braun J, Blanco R, Marzo-Ortega H, Gensler LS, Van den Bosch F, Hall S, Kameda H, Poddubnyy D, van de Sande M, van der Heijde D, Zhuang T, Stefanska A, Readie A, Richards HB, Deodhar A -
E089 Effect of secukinumab on radiographic progression and inflammation in sacroiliac joints and spine in patients with non-radiographic axial spondyloarthritis: 2-year imaging outcomes from a Phase III randomised trial.
Rheumatology 2023 Helena Marzo-Ortega, Juergen Braun, Ricardo Blanco, Lianne S Gensler, Filip van den Bosch, Stephen Hall, Hideto Kameda, Denis Poddubnyy, Marleen G H van de Sande, Désirée van der Heidje, Tingting … -
Characteristics associated with poor COVID-19 outcomes in people with psoriasis, psoriatic arthritis and axial spondyloarthritis: data from the COVID-19 PsoProtect and Global Rheumatology Alliance physician-reported registries.
Annals of the rheumatic diseases 2023 Machado PM, Schäfer M, Mahil SK, Liew J, Gossec L, Dand N, Pfeil A, Strangfeld A, Regierer AC, Fautrel B, Alonso CG, Saad CGS, Griffiths CEM, Lomater C, Miceli-Richard C, Wendling D, Alpizar Rodriguez… -
Sleep Disturbance and SARS-CoV-2 Vaccinations in Patients With Chronic Inflammatory Disease.
Arthritis care & research 2023 Pawar N, Taylor KE, Yang M, Deepak P, Kim W, Paley MA, Matloubian M, Carvidi A, Ciorba MA, Demissie E, El-Qunni A, Huang K, Kinnett B, McMorrow LE, Paez D, Poole M, Rose A, Schriefer RE, Kim AHJ, … -
Clinimetric Validation of the Assessment of Spondyloarthritis International Society Health Index in Patients With Radiographic Axial Spondyloarthritis in Ixekizumab Trials.
The Journal of rheumatology 2023 Kiltz U, van der Heijde D, Boonen A, Gensler LS, Gibble TH, Guo J, Carlier H, Braun J -
Efficacy and safety of bimekizumab in axial spondyloarthritis: results of two parallel phase 3 randomised controlled trials.
Annals of the rheumatic diseases 2023 van der Heijde D, Deodhar A, Baraliakos X, Brown MA, Dobashi H, Dougados M, Elewaut D, Ellis AM, Fleurinck C, Gaffney K, Gensler LS, Haroon N, Magrey M, Maksymowych WP, Marten A, Massow U, Oortgiesen … -
A simple point-of-care assay accurately detects anti-spike antibodies after SARS-CoV-2 vaccination.
Journal of clinical virology plus 2023 Greene SE, Huang Y, Kim W, Liebeskind MJ, Chandrasekaran V, Liu Z, Deepak P, Paley MA, Lew D, Yang M, Matloubian M, Gensler LS, Nakamura MC, O'Hallaran JA, Presti RM, Whelan SPJ, Buchser WJ, Kim AHJ, … -
Virtually Speaking: The Impact of a Nationwide Synchronous and Asynchronous Learning Forum.
Arthritis care & research 2022 Dua AB, Bolster MB, Gensler LS, Kolfenbach J, Mamut MH, Seo P, Jonas BL -
Amélioration des signes et symptômes chez des patients atteints de spondyloarthrite axiale radiographique traités par bimékizumab : résultats à 24 semaines d’une étude de phase III, multicentrique, randomisée et contrôlée par placebo.
Revue du Rhumatisme 2022 M. Dougados, D. Van Der Heijde, X. Baraliakos, M.A. Brown, D. Poddubnyy, F. Van Den Bosch, N. Haroon, H. Xu, T. Tomita, L.S. Gensler, M. Oortgiesen, C. Fleurinck, N. De Peyrecave, T. Vaux, A. Marten, … -
Amélioration des signes et symptômes chez les patients atteints de spondyloathrite axiale non radiographique traités par le bimékizumab : résultats à 24 semaines d’une étude de phase III.
Revue du Rhumatisme 2022 M. Breban, A. Deodhar, D. Van Der Heijde, L.S. Gensler, H. Xu, K. Gaffney, H. Dobashi, W. Maksymowych, M. Rudwaleit, M. Magrey, D. Elewaut, M. Oortgiesen, C. Fleurinck, N. De Peyrecave, A.M. Ellis, T.… -
Le bimékizumab améliore la fonction physique et la qualité de vie liée à l’état de santé chez les patients atteints de spondyloarthrite axiale : résultats de deux études de phase III.
Revue du Rhumatisme 2022 M. Breban, M. Dubreuil, K. Gaffney, L.S. Gensler, J. Kay, V. Navarro-Compán, C. De La Loge, A.M. Ellis, C. Fleurinck, M. Oortgiesen, V. Taieb, A. Deodhar -
Le bimékizumab améliore les principaux symptômes rapportés par les patients atteints de spondylarthrite axiale, notamment les douleurs rachidiennes et la fatigue : résultats de deux études de phase III.
Revue du Rhumatisme 2022 M. Dougados, P.J. Mease, A. Deodhar, M. Dubreuil, M. Magrey, H. Marzo-Ortega, M. Rudwaleit, C. De La Loge, A.M. Ellis, C. Fleurinck, M. Oortgiesen, V. Taieb, L.S. Gensler -
Taux de rétablissement de la réponse avec l’ixékizumab après l’arrêt du traitement chez des patients atteints de spondyloarthrite axiale : résultats à la semaine 104 d’une étude de retrait randomisé, contrôlée versus placebo.
Revue du Rhumatisme 2022 R.B. Landewé, D. Poddubnyy, P. Rahman, R. Bolce, S.L. Leage, J. Lisse, A. Leung, S.Y. Park, L.S. Gensler, C. Lukas -
The faecal microbiota is distinct in HLA-B27+ ankylosing spondylitis patients versus HLA-B27+ healthy controls.
Clinical and experimental rheumatology 2022 Stoll ML, Sawhney H, Wells PM, Sternes PR, Reveille JD, Morrow CD, Steves CJ, Brown MA, Gensler LS -
Safety and Efficacy of Bimekizumab in Patients With Active Ankylosing Spondylitis: Three-Year Results From a Phase IIb Randomized Controlled Trial and Its Open-Label Extension Study.
Arthritis & rheumatology (Hoboken, N.J.) 2022 Baraliakos X, Deodhar A, Dougados M, Gensler LS, Molto A, Ramiro S, Kivitz AJ, Poddubnyy D, Oortgiesen M, Vaux T, Fleurinck C, Shepherd-Smith J, de la Loge C, de Peyrecave N, van der Heijde D -
Ixekizumab in radiographic axial spondyloarthritis with and without elevated C-reactive protein or positive magnetic resonance imaging.
Rheumatology (Oxford, England) 2022 Maksymowych WP, Bolce R, Gallo G, Seem E, Geneus VJ, Sandoval DM, Østergaard M, Tada K, Baraliakos X, Deodhar A, Gensler LS -
ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update.
Annals of the rheumatic diseases 2022 Ramiro S, Nikiphorou E, Sepriano A, Ortolan A, Webers C, Baraliakos X, Landewé RBM, Van den Bosch FE, Boteva B, Bremander A, Carron P, Ciurea A, van Gaalen FA, Géher P, Gensler L, Hermann J, de Hooge … -
Why Do Some Patients Have Severe Sacroiliac Disease But No Syndesmophytes in Ankylosing Spondylitis? Data From a Nested Case-Control Study.
The Journal of rheumatology 2022 Ridley LK, Hwang MC, Reveille JD, Gensler LS, Ishimori ML, Brown MA, Rahbar MH, Tahanan A, Ward MM, Weisman MH, Learch TJ -
Sexual dimorphism in the prevalence, manifestation and outcomes of axial spondyloarthritis.
Nature reviews. Rheumatology 2022 Stovall R, van der Horst-Bruinsma IE, Liu SH, Rusman T, Gensler LS -
Recapture and retreatment rates with ixekizumab after withdrawal of therapy in patients with axial spondyloarthritis: results at week 104 from a randomised placebo-controlled withdrawal study.
Annals of the rheumatic diseases 2022 Landewé RBM, Poddubnyy D, Rahman P, Van den Bosch FE, Bolce R, Liu Leage S, Lisse JR, Park SY, Gensler L -
Reactogenicity of the Messenger RNA SARS-CoV-2 Vaccines Associated With Immunogenicity in Patients With Autoimmune and Inflammatory Disease.
Arthritis care & research 2022 Yang MM, Taylor KE, Paez D, Carividi A, Demissie E, Pawar N, El-Qunni AA, McMorrow LE, Schriefer RE, Huang K, Kinnett B, Klebert M, Haile A, O'Halloran JA, Presti RM, Kim W, Ellebedy AH, Ciorba MA, … -
Correction: Stoll et al. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children 2022, 9, 569.
Children (Basel, Switzerland) 2022 Stoll ML, DeQuattro K, Li Z, Sawhney H, Weiss PF, Nigrovic PA, Wright TB, Schikler K, Edelheit B, Morrow CD, Reveille JD, Brown MA, Gensler LS -
Minimal Impact of the COVID-19 Pandemic on Disease Activity and Health-Related Quality of Life in Patients With Ankylosing Spondylitis Receiving Bimekizumab: Exploratory Analyses From a Phase 2b Open-Label Extension Study.
ACR open rheumatology 2022 Robinson PC, Machado PM, Haroon N, Gensler LS, Reveille JD, Taieb V, Vaux T, Fleurinck C, Oortgiesen M, de Peyrecave N, Deodhar A -
Certolizumab Pegol Efficacy in Patients With Non-Radiographic Axial Spondyloarthritis Stratified by Baseline MRI and C-Reactive Protein Status: An Analysis From the C-axSpAnd Study.
ACR open rheumatology 2022 Robinson PC, Maksymowych WP, Gensler LS, Hall S, Rudwaleit M, Hoepken B, Bauer L, Kumke T, Kim M, de Peyrecave N, Deodhar A -
Instrument selection for the ASAS core outcome set for axial spondyloarthritis.
Annals of the rheumatic diseases 2022 Navarro-Compán V, Boel A, Boonen A, Mease PJ, Dougados M, Kiltz U, Landewé RBM, Baraliakos X, Bautista-Molano W, Chiowchanwisawakit P, Dagfinrud H, Fallon L, Garrido-Cumbrera M, Gensler L, ElZorkany … -
OP0017 RECAPTURE RATES WITH IXEKIZUMAB AFTER WITHDRAWAL OF THERAPY IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: RESULTS AT WEEK 104 FROM A RANDOMIZED PLACEBO-CONTROLLED WITHDRAWAL STUDY.
Annals of the Rheumatic Diseases 2022 R. B. M. Landewé, D. Poddubnyy, P. Rahman, R. Bolce, S. Liu Leage, J. Lisse, A. Leung, S. Y. Park, L. S. Gensler -
OP0019 BIMEKIZUMAB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 2, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO-CONTROLLED STUDY.
Annals of the Rheumatic Diseases 2022 D. Van der Heijde, X. Baraliakos, M. Dougados, M. Brown, D. Poddubnyy, F. Van den Bosch, N. Haroon, H. Xu, T. Tomita, L. S. Gensler, M. Oortgiesen, C. Fleurinck, T. Vaux, A. Marten, A. Deodhar -
OP0023 A RANDOMIZED, DOUBLE-BLIND TRIAL COMPARING SECUKINUMAB 300 MG AND 150 MG AT WEEK 52 IN PATIENTS WITH ANKYLOSING SPONDYLITIS WHO DID NOT ACHIEVE INACTIVE DISEASE DURING AN INITIAL 16 WEEKS OF OPEN-LABEL TREATMENT WITH SECUKINUMAB 150 MG.
Annals of the Rheumatic Diseases 2022 A. Deodhar, A. Kivitz, M. Magrey, J. A. Walsh, P. J. Mease, M. Greenwald, R. Calheiros, F. Kianifard, C. Elam, K. Nagar, A. Winseck, L. S. Gensler -
OP0154 COMORBIDITY CLUSTERS IN ANKYLOSING SPONDYLITIS AND THEIR ASSOCIATION WITH DISEASE ACTIVITY AND FUNCTIONAL IMPAIRMENT: DATA FROM THE PSOAS COHORT.
Annals of the Rheumatic Diseases 2022 P. Karmacharya, C. S. Crowson, D. Poudel, J. M. Davis, A. Ogdie, J. Liew, M. Ward, M. Ishimori, M. Weisman, M. Brown, M. Rahbar, M. Hwang, J. D. Reveille, L. S. Gensler -
POS0299 EFFECT OF SECUKINUMAB ON RADIOGRAPHIC PROGRESSION AND INFLAMMATION IN SACROILIAC JOINTS AND SPINE IN PATIENTS WITH NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 2-YEAR IMAGING OUTCOMES FROM A PHASE III RANDOMISED TRIAL.
Annals of the Rheumatic Diseases 2022 J. Braun, R. Blanco, H. Marzo-Ortega, L. S. Gensler, F. Van den Bosch, S. Hall, H. Kameda, D. Poddubnyy, M. G. H. Van de Sande, D. Van der Heijde, T. Zhuang, A. Stefanska, A. Readie, H. Richards, A. … -
POS0939 BIMEKIZUMAB IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 1, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO-CONTROLLED STUDY.
Annals of the Rheumatic Diseases 2022 A. Deodhar, D. Van der Heijde, L. S. Gensler, H. Xu, K. Gaffney, H. Dobashi, W. P. Maksymowych, M. Rudwaleit, M. Magrey, D. Elewaut, M. Oortgiesen, C. Fleurinck, A. Ellis, T. Vaux, J. Smith, X. … -
POS0941 LONG-TERM CLINICAL OUTCOMES OF CERTOLIZUMAB PEGOL TREATMENT IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS STRATIFIED BY BASELINE MRI AND C-REACTIVE PROTEIN STATUS.
Annals of the Rheumatic Diseases 2022 P. Robinson, W. P. Maksymowych, L. S. Gensler, M. Rudwaleit, B. Hoepken, L. Bauer, T. Kumke, M. Kim, A. Deodhar -
COVID-19 Outcomes and Vaccination in Patients with Spondyloarthritis.
Rheumatology and therapy 2022 Deodhar A, Bhana S, Winthrop K, Gensler LS -
Single Cell Transcriptome and Surface Epitope Analysis of Ankylosing Spondylitis Facilitates Disease Classification by Machine Learning.
Frontiers in immunology 2022 Alber S, Kumar S, Liu J, Huang ZM, Paez D, Hong J, Chang HW, Bhutani T, Gensler LS, Liao W -
Identifying trajectories of radiographic spinal disease in ankylosing spondylitis: a 15-year follow-up study of the PSOAS cohort.
Rheumatology (Oxford, England) 2022 Hwang MC, Lee M, Gensler LS, Brown MA, Tahanan A, Rahbar MH, Hunter T, Shan M, Ishimori ML, Reveille JD, Weisman MH, Learch TJ -
Su1481: IMPACT OF IMMUNOSUPPRESSIVE THERAPIES ON ANTIBODY DECAY FOLLOWING MRNA VACCINATION TO SARS-COV-2 IN A PROSPECTIVE COHORT OF PATIENTS WITH CHRONIC INFLAMMATORY DISEASES.
Gastroenterology 2022 Parakkal Deepak, Wooseob Kim, Michael Paley, Monica Yang, Samantha Burdess, Alexander B. Carvidi, Emanuel Demissie, Alia A. El-Qunni, Alem Haile, Katherine Huang, Guadalupe Oliva Escudero, Lily E. … -
Relationship Between Body Mass Index, Disease Activity, and Exercise in Ankylosing Spondylitis.
Arthritis care & research 2022 Liew JW, Gianfrancesco MA, Heckbert SR, Gensler LS -
Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients.
Children (Basel, Switzerland) 2022 Stoll ML, DeQuattro K, Li Z, Sawhney H, Weiss PF, Nigrovic PA, Wright TB, Schikler K, Edelheit B, Morrow CD, Reveille JD, Brown MA, Gensler LS -
Combined Single Cell Transcriptome and Surface Epitope Profiling Identifies Potential Biomarkers of Psoriatic Arthritis and Facilitates Diagnosis via Machine Learning.
Frontiers in immunology 2022 Liu J, Kumar S, Hong J, Huang ZM, Paez D, Castillo M, Calvo M, Chang HW, Cummins DD, Chung M, Yeroushalmi S, Bartholomew E, Hakimi M, Ye CJ, Bhutani T, Matloubian M, Gensler LS, Liao W -
Long-term safety and clinical outcomes of certolizumab pegol treatment in patients with active non-radiographic axial spondyloarthritis: 3-year results from the phase 3 C-axSpAnd study.
RMD open 2022 van der Heijde D, Gensler LS, Maksymowych WP, Landewé R, Rudwaleit M, Bauer L, Kumke T, Kim M, Auteri SE, Hoepken B, Deodhar A -
Improvement of Functioning and Health With Ixekizumab in the Treatment of Active Nonradiographic Axial Spondyloarthritis in a 52-Week, Randomized, Controlled Trial.
Arthritis care & research 2022 Walsh JA, Magrey MN, Baraliakos X, Inui K, Weng MY, Lubrano E, van der Heijde D, Boonen A, Gensler LS, Strand V, Braun J, Hunter T, Li X, Zhu B, León L, Calderon DMS, Kiltz U -
Endpoints for extraintestinal manifestations in inflammatory bowel disease trials: the EXTRA consensus from the International Organization for the Study of Inflammatory Bowel Diseases.
The lancet. Gastroenterology & hepatology 2022 Guillo L, Abreu M, Panaccione R, Sandborn WJ, Azevedo VF, Gensler L, Moghaddam B, Ahuja V, Ali SA, Allez M, Ananthakrishnan AN, Bhattacharya A, Dubinsky M, Griffiths A, Hart A, Korelitz B, Kotze PG, … -
Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).
Therapeutic advances in musculoskeletal disease 2021 Poddubnyy D, Baraliakos X, Van den Bosch F, Braun J, Coates LC, Chandran V, Diekhoff T, van Gaalen FA, Gensler LS, Goel N, Gottlieb AB, van der Heijde D, Helliwell PS, Hermann KGA, Jadon D, Lambert RG… -
Effects of secukinumab on bone mineral density and bone turnover biomarkers in patients with ankylosing spondylitis: 2-year data from a phase 3 study, MEASURE 1.
BMC musculoskeletal disorders 2021 Braun J, Buehring B, Baraliakos X, Gensler LS, Porter B, Quebe-Fehling E, Haemmerle S -
A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programs.
Medical education online 2021 Huppert LA, Hsu G, Elnachef N, Flint L, Frank JA, Gensler LS, Hsiao EC, Khanna RR, Qasim A, Schwartz BS, Widera E, Zapata C, Babik JM -
Poursuite ou arrêt du traitement par l’ixékizumab chez des patients atteints de spondyloarthrite axiale et ayant atteint la rémission : résultats d’une étude de retrait randomisé, contrôlée versus placebo.
Revue du Rhumatisme 2021 R. Landewé, L. Gensler, D. Poddubnyy, P. Rahman, M. Hojnik, X. Li, S. Liu-Leage, D. Adams, H. Carlier, F. Van den Bosch, C. Lukas -
The Association of Tumor Necrosis Factor Inhibitor Use With Incident Hypertension in Ankylosing Spondylitis: Data From the PSOAS Cohort.
The Journal of rheumatology 2021 Liew JW, Jafarzadeh SR, Dubreuil M, Heckbert SR, Mooney SJ, Brown MA, Ishimori ML, Reveille JD, Ward MM, Weisman MH, Gensler LS -
Tolérance et efficacité à long terme du bimékizumab chez les patients atteints de spondylarthrite ankylosante : résultats à 3 ans d’une étude de phase IIb.
Revue du Rhumatisme 2021 D. Van Der Heijde, A. Deodhar, L. Gensler, D. Poddubnyy, A. Kivitz, M. Dougados, N. De Peyrecave, M. Oortgiesen, T. Vaux, C. Fleurinck, X. Baraliakos -
Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT.
Arthritis research & therapy 2021 Braun J, Blanco R, Marzo-Ortega H, Gensler LS, van den Bosch F, Hall S, Kameda H, Poddubnyy D, van de Sande M, Wiksten AS, Porter BO, Shete A, Richards HB, Haemmerle S, Deodhar A -
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Annals of internal medicine 2021 Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, Demissie EG, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Pawar N, Perantie DC, Schriefer RE, Sides SE, Thapa M, … -
The ASAS-OMERACT core domain set for axial spondyloarthritis.
Seminars in arthritis and rheumatism 2021 Navarro-Compán V, Boel A, Boonen A, Mease P, Landewé R, Kiltz U, Dougados M, Baraliakos X, Bautista-Molano W, Carlier H, Chiowchanwisawakit P, Dagfinrud H, de Peyrecave N, El-Zorkany B, Fallon L, … -
Repeated Spinal Mobility Measures and Their Association With Radiographic Damage in Ankylosing Spondylitis.
ACR open rheumatology 2021 Hwang MC, Lee M, Gensler LS, Ward MM, Brown MA, Learch TJ, Tahanan A, Rahbar MH, Ishimori M, Weisman MH, Reveille JD, PSOAS Study Investigators -
OP0255 THE ROLE OF PELVIC MORPHOLOGY IN AXIAL SPONDYLOARTHRITIS.
Annals of the Rheumatic Diseases 2021 E. Zaccagnino, R. Patel, L. S. Gensler -
POS0226 BIMEKIZUMAB LONG-TERM SAFETY AND EFFICACY IN PATIENTS WITH ANKYLOSING SPONDYLITIS: 3-YEAR RESULTS FROM A PHASE 2B STUDY.
Annals of the Rheumatic Diseases 2021 D. Van der Heijde, A. Deodhar, L. S. Gensler, D. Poddubnyy, A. Kivitz, M. Dougados, N. De Peyrecave, M. Oortgiesen, T. Vaux, C. Fleurinck, X. Baraliakos -
POS0229 DISEASE ACTIVITY AND INFLAMMATION FOLLOWING WITHDRAWAL OF CERTOLIZUMAB PEGOL TREATMENT IN AXIAL SPONDYLOARTHRITIS PATIENTS WHO DID NOT EXPERIENCE FLARES DURING THE C-OPTIMISE STUDY.
Annals of the Rheumatic Diseases 2021 L. S. Gensler, X. Baraliakos, L. Bauer, B. Hoepken, T. Kumke, M. Kim, R. B. M. Landewé -
POS0904 FACTORS ASSOCIATED WITH SWITCHING FROM ONE ANTI-TNF AGENT TO ANOTHER ANTI-TNF, OR IL17 AGENT IN PATIENT WITH ANKYLOSING SPONDYLITIS.
Annals of the Rheumatic Diseases 2021 M. Hwang, M. Weisman, L. S. Gensler, A. Tahanan, M. Ishimori, T. Hunter, R. Bolce, J. Lisse, M. Rahbar, M. Shan, J. D. Reveille -
POS0923 INFLUENCE OF BASELINE DEMOGRAPHICS ON IMPROVEMENTS IN DISEASE ACTIVITY MEASURES IN PATIENTS WITH ANKYLOSING SPONDYLITIS RECEIVING UPADACITINIB: A POST HOC SUBGROUP ANALYSIS OF SELECT-AXIS 1.
Annals of the Rheumatic Diseases 2021 F. Van den Bosch, D. Poddubnyy, J. Stigler, A. Ostor, S. D’angelo, V. Navarro-Compán, I. H. Song, T. Gao, F. Ganz, L. S. Gensler -
POS1255 REACTOGENICITY OF SARS-COV-2 VACCINES IN PATIENTS WITH AUTOIMMUNE AND INFLAMMATORY DISEASE.
Annals of the Rheumatic Diseases 2021 M. Yang, P. Katz, D. Paez, A. Carvidi, M. Matloubian, M. Nakamura, L. S. Gensler -
Continuing versus withdrawing ixekizumab treatment in patients with axial spondyloarthritis who achieved remission: efficacy and safety results from a placebo-controlled, randomised withdrawal study (COAST-Y).
Annals of the rheumatic diseases 2021 Landewé RB, Gensler LS, Poddubnyy D, Rahman P, Hojnik M, Li X, Liu Leage S, Adams D, Carlier H, Van den Bosch F, COAST-Y study group -
Tofacitinib for the treatment of ankylosing spondylitis: a phase III, randomised, double-blind, placebo-controlled study.
Annals of the rheumatic diseases 2021 Deodhar A, Sliwinska-Stanczyk P, Xu H, Baraliakos X, Gensler LS, Fleishaker D, Wang L, Wu J, Menon S, Wang C, Dina O, Fallon L, Kanik KS, van der Heijde D -
Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis.
Annals of the rheumatic diseases 2021 Li Z, Wu X, Leo PJ, De Guzman E, Akkoc N, Breban M, Macfarlane GJ, Mahmoudi M, Marzo-Ortega H, Anderson LK, Wheeler L, Chou CT, Harrison AA, Stebbings S, Jones GT, Bang SY, Wang G, Jamshidi A, Farhadi… -
Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2.
medRxiv : the preprint server for health sciences 2021 Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Perantie DC, Schriefer RE, Sides SE, Thapa M, Gergely M, Abushamma S… -
Secukinumab Efficacy on Enthesitis in Patients With Ankylosing Spondylitis: Pooled Analysis of Four Pivotal Phase III Studies.
The Journal of rheumatology 2021 Schett G, Baraliakos X, Van den Bosch F, Deodhar A, Østergaard M, Gupta AD, Mpofu S, Fox T, Winseck A, Porter B, Shete A, Gensler LS -
Do geography and ethnicity play a role in juvenile Spondyloarthritis? A multi-center binational retrospective study.
Pediatric rheumatology online journal 2021 Ghantous N, Heshin-Bekenstein M, Dequattro K, Lakovsky Y, Hendel AM, Rappoport N, Aviel YB, Tirosh I, Harel L, Weiss PF, Gensler L, Mackenzie J, Amarilyo G -
Achievement of Remission Endpoints with Secukinumab Over 3 Years in Active Ankylosing Spondylitis: Pooled Analysis of Two Phase 3 Studies.
Rheumatology and therapy 2020 Baraliakos X, Van den Bosch F, Machado PM, Gensler LS, Marzo-Ortega H, Sherif B, Quebe-Fehling E, Porter B, Gaillez C, Deodhar A -
Efficacité et sécurité d’emploi du bimekizumab dans la spondylarthrite ankylosante : résultats rapportés par les patients à 48 semaines dans une étude de phase IIb de détermination de la dose, randomisée, en double aveugle, contrôlée versus placebo.
Revue du Rhumatisme 2020 D. Van Der Heijde, L. Gensler, A. Deodhar, X. Baraliakos, D. Poddubnyy, A. Kivitz, M. Farmer, D. Baeten, N. Goldammer, J. Coarse, M. Oortgiesen, M. Dougados -
Efficacité et tolérance à 52 semaines de l’ixékizumab dans la spondyloarthrite axiale radiographique chez des patients en réponse inadéquate ou intolérants aux anti-TNF.
Revue du Rhumatisme 2020 M. Dougados, J. Sieper, X. Baraliakos, F. Van den Bosch, W. Maksymowych, J. Ermann, X. Li, G. Gallo, H. Carlier, L. Gensler, E. Lespessailles -
Ixékizumab dans la spondyloarthrite axiale non-radiographique : résultats d’un essai de phase 3.
Revue du Rhumatisme 2020 A. Deodhar, D. Van Der Heijde, L. Gensler, T.H. Kim, W. Maksymowych, M. Ostergaard, D. Poddubnyy, H. Marzo-Ortega, L. Bessette, T. Tomita, G. Gallo, D.H. Adams, A. Leung, F. Zhao, M. Hojnik, H. … -
Le genre, l’âge ou la sous-population influencent-ils le maintien de la rémission clinique dans la spondyloarthrite axiale après une réduction de la dose de certolizumab pegol?.
Revue du Rhumatisme 2020 R. Landewé, D. Van Der Heijde, M. Dougados, X. Baraliakos, F. Van den Bosch, K. Gaffney, L. Bauer, B. Hoepken, N. De Peyrecave, T. Kumke, L. Gensler -
Le sécukinumab améliore les signes et symptômes de la spondyloarthrite axiale non radiographique : résultats d’une étude de phase III randomisée, contrôlée, stratifiée sur les signes objectifs d’inflammation à l’inclusion.
Revue du Rhumatisme 2020 P. Goupille, J. Braun, R. Blanco, H. Marzo-Ortega, L. Gensler, F. Van den Bosch, H. Kameda, D. Poddubnyy, M. Van De Sande, A. Wiksten, B. Porter, S.G. Moreno, A. Shete, H. Richards, S. Haemmerle, A. … -
Chronic back pain in first-degree relatives (FDRs) of patients with ankylosing spondylitis: predictive value of HLA-B27 and persistence of inflammatory back pain over time.
RMD open 2020 Doughem K, Weisman MH, Ward MM, Gensler LS, Ishimori M, Tahanan A, Kung DC, Diekman L, Lee M, Rahbar MH, Reveille JD -
Nonsteroidal Antiinflammatory Drug Use and Association With Incident Hypertension in Ankylosing Spondylitis.
Arthritis care & research 2020 Liew JW, Ward MM, Reveille JD, Weisman M, Brown MA, Lee M, Rahbar M, Heckbert SR, Gensler LS -
Patient-reported Disease Activity in an Axial Spondyloarthritis Cohort during the COVID-19 Pandemic.
ACR open rheumatology 2020 Liew JW, Castillo M, Zaccagnino E, Katz P, Haroon N, Gensler LS -
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 Pivotal Studies.
The Journal of rheumatology 2020 Kiltz U, Wei JC, van der Heijde D, van den Bosch F, Walsh JA, Boonen A, Gensler LS, Hunter T, Carlier H, Dong Y, Li X, Bolce R, Strand V, Braun J -
The changing profile of ankylosing spondylitis in the biologic era.
Clinical rheumatology 2020 Reveille JD, Lee M, Gensler LS, Ward MM, Hwang MC, Learch TJ, Tahanan A, Diekman L, Rahbar MH, Ishimori ML, Weisman MH -
Cardiovascular Risk Scores in Axial Spondyloarthritis Versus the General Population: A Cross-sectional Study.
The Journal of rheumatology 2020 Liew JW, Reveille JD, Castillo M, Sawhney H, Naovarat BS, Heckbert SR, Gensler LS -
AB1358-HPR DIAGNOSIS OF AXIAL SPONDYLOARTHRITIS: A PRIMARY UNMET EDUCATIONAL NEED FOR RHEUMATOLOGISTS.
Annals of the Rheumatic Diseases 2020 W. P. Maksymowych, L. Caplan, A. Deodhar, S. Dolatabadi, M. Hwang, A. Carlson, K. Steed, A. Carapellucci, J. Paschke, L. S. Gensler -
Induction of Sustained Clinical Remission in Early Axial Spondyloarthritis Following Certolizumab Pegol Treatment: 48-Week Outcomes from C-OPTIMISE.
Rheumatology and therapy 2020 Landewé R, van der Heijde D, Dougados M, Baraliakos X, Van den Bosch F, Gaffney K, Bauer L, Hoepken B, de Peyrecave N, Thomas K, Gensler LS -
Examining Treatment Decision-Making Among Patients With Axial Spondyloarthritis: Insights From a Conjoint Analysis Survey.
ACR open rheumatology 2020 Joo W, Almario CV, Ishimori M, Park Y, Jusufagic A, Noah B, Gensler LS, Venuturupalli RS, Kay J, Weisman MH, Spiegel BMR -
Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.
Investigative ophthalmology & visual science 2020 Huang XF, Li Z, De Guzman E, Robinson P, Gensler L, Ward MM, Rahbar MH, Lee M, Weisman MH, Macfarlane GJ, Jones GT, Klingberg E, Forsblad-d'Elia H, McCluskey P, Wakefield D, Coombes JS, Fiatarone … -
OP0060 MACHINE LEARNING BASED BERLIN SCORING OF MAGNETIC RESONANCE IMAGES OF THE SPINE IN PATIENTS WITH ANKYLOSING SPONDYLITIS FROM THE MEASURE 1 STUDY.
Annals of the Rheumatic Diseases 2020 A. Jamaludin, R. Windsor, S. Ather, T. Kadir, A. Zisserman, J. Braun, L. S. Gensler, P. Machado, M. ?stergaard, D. Poddubnyy, T. Coroller, B. Porter, S. Mpofu, A. Readie -
OP0103 DOES GENDER, AGE OR SUBPOPULATION INFLUENCE THE MAINTENANCE OF CLINICAL REMISSION IN AXIAL SPONDYLOARTHRITIS FOLLOWING CERTOLIZUMAB PEGOL DOSE REDUCTION?.
Annals of the Rheumatic Diseases 2020 R. B. M. Landewé, D. Van der Heijde, M. Dougados, X. Baraliakos, F. Van den Bosch, K. Gaffney, L. Bauer, B. Hoepken, N. De Peyrecave, K. Thomas, L. S. Gensler -
OP0105 EFFICACY AND SAFETY OF BIMEKIZUMAB IN ANKYLOSING SPONDYLITIS: 48-WEEK PATIENT-REPORTED OUTCOMES FROM A PHASE 2B, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY.
Annals of the Rheumatic Diseases 2020 D. Van der Heijde, L. S. Gensler, A. Deodhar, X. Baraliakos, D. Poddubnyy, A. Kivitz, M. K. Farmer, D. Baeten, N. Goldammer, J. Coarse, M. Oortgiesen, M. Dougados -
OP0106 SECUKINUMAB 150 MG SIGNIFICANTLY IMPROVED SIGNS AND SYMPTOMS OF NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 52-WEEK RESULTS FROM THE PHASE III PREVENT STUDY.
Annals of the Rheumatic Diseases 2020 J. Braun, R. Blanco, E. Dokoupilova, L. S. Gensler, A. Kivitz, S. Hall, H. Kameda, D. Poddubnyy, M. Van de Sande, D. Van der Heijde, A. Wiksten, B. Porter, H. Richards, S. Haemmerle, A. Deodhar -
THU0384 IMPACT OF IXEKIZUMAB ON WORK PRODUCTIVITY IN NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS PATIENTS: RESULTS FROM THE COAST-X TRIAL AT 52 WEEKS.
Annals of the Rheumatic Diseases 2020 A. Deodhar, P. J. Mease, L. S. Gensler, P. Rahman, V. Navarro-Compán, H. Marzo-Ortega, T. Hunter, D. Sandoval, A. Kronbergs, B. Zhu, A. Leung, V. Strand -
THU0395 EFFICACY OF IXEKIZUMAB ON DISEASE ACTIVITY AND QUALITY OF LIFE IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS AND OBJECTIVE SIGNS OF INFLAMMATION, STRATIFIED BY BASELINE CRP/SACROILIAC JOINT MRI STATUS.
Annals of the Rheumatic Diseases 2020 W. P. Maksymowych, H. Marzo-Ortega, M. ?stergaard, L. S. Gensler, J. Ermann, A. Deodhar, D. Poddubnyy, D. Sandoval, R. Bolce, A. Kronbergs, S. Liu Leage, G. Doridot, V. Geneus, A. Leung, D. Adams, M. … -
Maintenance of clinical remission in early axial spondyloarthritis following certolizumab pegol dose reduction.
Annals of the rheumatic diseases 2020 Landewé RB, van der Heijde D, Dougados M, Baraliakos X, Van den Bosch FE, Gaffney K, Bauer L, Hoepken B, Davies OR, de Peyrecave N, Thomas K, Gensler LS -
Propensity score matching/reweighting analysis comparing intravenous golimumab to infliximab for ankylosing spondylitis using data from the GO-ALIVE and ASSERT trials.
Clinical rheumatology 2020 Gensler LS, Chakravarty SD, Cameron C, Peterson S, Spin P, Kafka S, Nair S, Deodhar A -
Association of body mass index on disease activity in axial spondyloarthritis: systematic review and meta-analysis.
RMD open 2020 Liew JW, Huang IJ, Louden DN, Singh N, Gensler LS -
Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study.
Annals of the rheumatic diseases 2020 van der Heijde D, Gensler LS, Deodhar A, Baraliakos X, Poddubnyy D, Kivitz A, Farmer MK, Baeten D, Goldammer N, Coarse J, Oortgiesen M, Dougados M -
EP38 Secukinumab provides sustained improvement of enthesitis in patients with ankylosing spondylitis: pooled analysis of four pivotal Phase 3 studies.
Rheumatology 2020 Nick Barkham, Georg Schett, Xenofon Baraliakos, Filip van den Bosch, Atul Deodhar, Lianne S Gensler, Mikkel ?stergaard, Shital Agawane, Ayan Das Gupta, Shephard Mpofu, Todd Fox, Adam Winseck, Abhijit … -
P242 CZP improves work and household productivity and social participation over 1 year of treatment in patients with non-radiographic axSpA.
Rheumatology 2020 Karl Gaffney, Atul Deodhar, Lianne Gensler, Jonathan Kay, Walter Maksymowych, Nigil Haroon, Robert Landewé, Martin Rudwaleit, Stephen Hall, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Thomas … -
P284 Certolizumab pegol-treated patients with non-radiographic axSpA demonstrate improvements in sleep quality and other patient reported outcomes.
Rheumatology 2020 Raj Sengupta, Lianne Gensler, Jonathan Kay, Walter Maksymowych, Nigil Haroon, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Thomas Kumke, Atul Deodhar -
Longitudinal associations between depressive symptoms and clinical factors in ankylosing spondylitis patients: analysis from an observational cohort.
Rheumatology international 2020 Hwang MC, Lee MJ, Gensler LS, Ward MM, Brown MA, Eisen S, Learch TJ, Tahanan A, Rahbar MH, Ishimori ML, Weisman MH, Reveille JD -
Biologic therapy and spinal radiographic progression in patients with axial spondyloarthritis: A structured literature review.
Therapeutic advances in musculoskeletal disease 2020 Baraliakos X, Gensler LS, D'Angelo S, Iannone F, Favalli EG, de Peyrecave N, Auteri SE, Caporali R -
Comparison of the Effects of Secukinumab and Adalimumab Biosimilar on Radiographic Progression in Patients with Ankylosing Spondylitis: Design of a Randomized, Phase IIIb Study (SURPASS).
Clinical drug investigation 2020 Baraliakos X, Østergaard M, Gensler LS, Poddubnyy D, Lee EY, Kiltz U, Martin R, Sawata H, Readie A, Porter B, SURPASS Study Group -
A systematic review and network meta-analysis of current and investigational treatments for active ankylosing spondylitis.
Clinical rheumatology 2020 Deodhar A, Chakravarty SD, Cameron C, Peterson S, Hensman R, Fogarty S, Spin P, Kafka S, Nair S, Gensler LS -
Effects of ustekinumab on spondylitis-associated endpoints in TNFi-naïve active psoriatic arthritis patients with physician-reported spondylitis: pooled results from two phase 3, randomised, controlled trials.
RMD open 2020 Helliwell PS, Gladman DD, Chakravarty SD, Kafka S, Karyekar CS, You Y, Campbell K, Sweet K, Kavanaugh A, Gensler LS -
Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial.
Lancet (London, England) 2019 Deodhar A, van der Heijde D, Gensler LS, Kim TH, Maksymowych WP, Østergaard M, Poddubnyy D, Marzo-Ortega H, Bessette L, Tomita T, Leung A, Hojnik M, Gallo G, Li X, Adams D, Carlier H, Sieper J, COAST-… -
A Terminal Event. Reply.
The New England journal of medicine 2019 Lai AR, Gensler LS, McQuaid K -
A latent class based imputation method under Bayesian quantile regression framework using asymmetric Laplace distribution for longitudinal medication usage data with intermittent missing values.
Journal of biopharmaceutical statistics 2019 Lee M, Rahbar MH, Gensler LS, Brown M, Weisman M, Reveille JD -
Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W).
Annals of the rheumatic diseases 2019 Dougados M, Wei JC, Landewé R, Sieper J, Baraliakos X, Van den Bosch F, Maksymowych WP, Ermann J, Walsh JA, Tomita T, Deodhar A, van der Heijde D, Li X, Zhao F, Bertram CC, Gallo G, Carlier H, Gensler… -
Assessing Physical Activity and Sleep in Axial Spondyloarthritis: Measuring the Gap.
Rheumatology and therapy 2019 Deodhar A, Gensler LS, Magrey M, Walsh JA, Winseck A, Grant D, Mease PJ -
Does psoriatic axial spondyloarthritis phenotype correlate with imaging morphotype?
Clinical and experimental rheumatology 2019 Gensler LS, Szumski A, Jones HE, Baraliakos X -
A Terminal Event.
The New England journal of medicine 2019 Lai AR, Sheu L, Gensler LS, McQuaid K, Dhaliwal G -
2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2019 Ward MM, Deodhar A, Gensler LS, Dubreuil M, Yu D, Khan MA, Haroon N, Borenstein D, Wang R, Biehl A, Fang MA, Louie G, Majithia V, Ng B, Bigham R, Pianin M, Shah AA, Sullivan N, Turgunbaev M, … -
2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Arthritis care & research 2019 Ward MM, Deodhar A, Gensler LS, Dubreuil M, Yu D, Khan MA, Haroon N, Borenstein D, Wang R, Biehl A, Fang MA, Louie G, Majithia V, Ng B, Bigham R, Pianin M, Shah AA, Sullivan N, Turgunbaev M, … -
Do patients with axial spondyloarthritis with radiographic sacroiliitis fulfil both the modified New York criteria and the ASAS axial spondyloarthritis criteria? Results from eight cohorts.
Annals of the rheumatic diseases 2019 Boel A, Molto A, van der Heijde D, Ciurea A, Dougados M, Gensler LS, Santos MJ, De Miguel E, Poddubnyy D, Rudwaleit M, van Tubergen A, van Gaalen FA, Ramiro S -
MR distribution of active inflammatory and chronic structural sacroiliac joint changes in axial spondyloarthropathy: Challenging conventional wisdom.
Clinical imaging 2019 Motamedi D, Patel R, Devulapalli KK, Gensler LS, Steinbach L -
AB0711 IXEKIZUMAB IMPROVES SIGNS AND SYMPTOMS AND SPINAL INFLAMMATION OF ANKYLOSING SPONDYLITIS/RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS THROUGH ONE YEAR OF TREATMENT IN BIOLOGIC DISEASE MODIFYING ANTI-RHEUMATIC DRUG-NAÏVE PATIENTS.
Abstracts accepted for Publication 2019 James Cheng-Chung Wei, Lianne S. Gensler, Jessica a. Walsh, Robert B.M. Landewé, Tetsuya Tomita, Fangyi Zhao, Gaia Gallo, Hilde Carlier, Maxime Dougados -
AB1321 PSYCHOMETRIC PROPERTIES OF THE ASAS HEALTH INDEX IN PATIENTS WITH ACTIVE AS/RADIOGRAPHIC AXIAL SPA WHO HAVE PRIOR INADEQUATE RESPONSE/INTOLERANCE TO TNF INHIBITORS IN A PHASE 3 TRIAL.
Abstracts Accepted for Publication 2019 Uta Kiltz, Désirée van der Heijde, Annelies Boonen, Lianne S. Gensler, Theresa Hunter, Kathleen Wyrwich, Yan Dong, LI Xiaoqi, Gaia Gallo, Juergen Braun -
Correction to: Ustekinumab Safety in Psoriasis, Psoriatic Arthritis, and Crohn's Disease: An Integrated Analysis of Phase II/III Clinical Development Programs.
Drug safety 2019 Ghosh S, Gensler LS, Yang Z, Gasink C, Chakravarty SD, Farahi K, Ramachandran P, Ott E, Strober BE -
FRI0380 SECUKINUMAB PROVIDES SUSTAINED IMPROVEMENT OF ENTHESITIS IN PATIENTS WITH ANKYLOSING SPONDYLITIS: POOLED ANALYSIS OF FOUR PIVOTAL PHASE 3 STUDIES.
Spondyloarthritis – treatment 2019 Georg Schett, Xenofon Baraliakos, Filip van den Bosch, Atul Deodhar, Lianne S. Gensler, Mikkel ?stergaard, Shital Agawane, Ayan Das Gupta, Shephard Mpofu, Todd Fox, Adam Winseck, Abhijit Shete, Brian … -
FRI0397 EFFICACY AND SAFETY OUTCOMES IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS TREATED WITH CERTOLIZUMAB PEGOL: RESULTS FROM THE 48-WEEK RUN-IN PART OF C-OPTIMISE.
Spondyloarthritis – treatment 2019 Robert B.M. Landewé, Désirée van der Heijde, Maxime Dougados, Xenofon Baraliakos, Filip van den Bosch, Karl Gaffney, Natasha de Peyrecave, Lars Bauer, Bengt Hoepken, Karen Thomas, Lianne S. Gensler -
FRI0398 IXEKIZUMAB IS EFFECTIVE IN THE TREATMENT OF RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS REGARDLESS OF THE LEVEL OF C-REACTIVE PROTEIN OR MAGNETIC RESONANCE IMAGING SCORES: 16-WEEK DATA FROM COAST-V AND COAST-W.
Spondyloarthritis – treatment 2019 Walter P. Maksymowych, Gaia Gallo, Rebecca Bolce, Fangyi Zhao, Vladimir Geneus, Mikkel ?stergaard, Kurisu Tada, Atul Deodhar, Lianne S. Gensler -
FRI0408 EARLIER TREATMENT OF NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS WITH CERTOLIZUMAB PEGOL RESULTS IN IMPROVED CLINICAL OUTCOMES.
Spondyloarthritis – treatment 2019 Martin Rudwaleit, Lianne S. Gensler, Atul Deodhar, Jonathan Kay, Walter P. Maksymowych, Nigil Haroon, Robert B.M. Landewé, Simone Auteri, Natasha de Peyrecave, Thomas Kumke, Désirée van der Heijde -
OP0031 ARE THE MODIFIED NEW YORK AND ASAS AXIAL SPONDYLOARTHRITIS CRITERIA INTERCHANGEABLE IN THE CLASSIFICATION OF SPONDYLOARTHRITIS PATIENTS WITH RADIOGRAPHIC SACROILIITIS: COMPARISON IN 8 COHORTS?.
Oral Presentations 2019 Anne Boel, Anna Moltó, Désirée van der Heijde, Adrian Ciurea, Maxime Dougados, Lianne S. Gensler, Maria Jose Santos, Eugenio de Miguel, Denis Poddubnyy, Martin Rudwaleit, Astrid van Tubergen, Floris A… -
OP0231 DUAL NEUTRALISATION OF IL-17A AND IL-17F WITH BIMEKIZUMAB WAS ASSOCIATED WITH IMPROVEMENTS IN PATIENT-REPORTED AND QUALITY-OF-LIFE OUTCOMES IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: RESULTS FROM A PHASE 2B, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY.
Oral Presentations 2019 Désirée van der Heijde, Lianne S. Gensler, Atul Deodhar, Xenofon Baraliakos, Denis Poddubnyy, Mary Katherine Farmer, Dominique Baeten, Jason Coarse, Marga Oortgiesen, Maxime Dougados -
THU0385 COMPARISON OF CLINICAL AND DEMOGRAPHIC FEATURES OF JUVENILE SPONDYLOARTHRITIS BETWEEN ISRAELI AND US CHILDREN.
Poster Presentations 2019 Merav Heshin-Bekenstein, Naseem Ghantous, Irit Tirosh, Yonatan Butbul, Liora Harel, Yaniv Lakovsky, Pamela Weiss, Nadav Rappoport, Kimberly Dequattro, Emily von Scheven, Lianne S. Gensler, Amir Hendel… -
Ustekinumab Safety in Psoriasis, Psoriatic Arthritis, and Crohn's Disease: An Integrated Analysis of Phase II/III Clinical Development Programs.
Drug safety 2019 Ghosh S, Gensler LS, Yang Z, Gasink C, Chakravarty SD, Farahi K, Ramachandran P, Ott E, Strober BE -
A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2019 Deodhar A, Gensler LS, Kay J, Maksymowych WP, Haroon N, Landewé R, Rudwaleit M, Hall S, Bauer L, Hoepken B, de Peyrecave N, Kilgallen B, van der Heijde D -
E098 Efficacy and safety outcomes in patients with axial spondyloarthritis treated with certolizumab pegol: results from the 48-week run-in part of a 96-week study (NCT02505542).
Rheumatology 2019 Robert Landewe, Desiree van der Heijde, Maxime Dougados, Xenofon Baraliakos, Filip Van den Bosch, Karl Gaffney, Bengt Hoepken, Karen Thomas, Lianne S Gensler -
Cardiovascular morbidity and mortality in ankylosing spondylitis and psoriatic arthritis.
Best practice & research. Clinical rheumatology 2019 Liew JW, Ramiro S, Gensler LS -
Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2018 Deodhar A, Gensler LS, Sieper J, Clark M, Calderon C, Wang Y, Zhou Y, Leu JH, Campbell K, Sweet K, Harrison DD, Hsia EC, van der Heijde D -
Nonradiographic axial spondyloarthritis.
Best practice & research. Clinical rheumatology 2018 Lockwood MM, Gensler LS -
Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active ankylosing spondylitis (TORTUGA): results from a randomised, placebo-controlled, phase 2 trial.
Lancet (London, England) 2018 van der Heijde D, Baraliakos X, Gensler LS, Maksymowych WP, Tseluyko V, Nadashkevich O, Abi-Saab W, Tasset C, Meuleners L, Besuyen R, Hendrikx T, Mozaffarian N, Liu K, Greer JM, Deodhar A, Landewé R -
HLA class I and II alleles in susceptibility to ankylosing spondylitis.
Annals of the rheumatic diseases 2018 Reveille JD, Zhou X, Lee M, Weisman MH, Yi L, Gensler LS, Zou H, Ward MM, Ishimori ML, Learch TJ, He D, Rahbar MH, Wang J, Brown MA -
LB0001 Dual neutralisation of il-17a and il-17f with bimekizumab in patients with active ankylosing spondylitis (AS): 12-week results from a phase 2b, randomised, double-blind, placebo-controlled, dose-ranging study.
Annals of the Rheumatic Diseases 2018 D. van der Heijde, L.S. Gensler, A. Deodhar, X. Baraliakos, D. Poddubnyy, M.K. Farmer, D. Baeten, T. Kumke, M. Oortgiesen, M. Dougados -
Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis.
Annals of the rheumatic diseases 2018 Kiltz U, van der Heijde D, Boonen A, Akkoc N, Bautista-Molano W, Burgos-Vargas R, Wei JC, Chiowchanwisawakit P, Dougados M, Duruoz MT, Elzorkany BK, Gaydukova I, Gensler LS, Gilio M, Grazio S, Gu J, … -
OP0198 Combined effects of tumour necrosis factor inhibitors and nsaids on radiographic progression in ankylosing spondylitis.
Annals of the Rheumatic Diseases 2018 L.S. Gensler, M. Gianfrancesco, M.H. Weisman, M.A. Brown, M. Lee, T. Learch, M. Rahbar, J.D. Reveille, M.M. Ward -
THU0242 Pregnancy outcomes and disease activity in women with axial spondyloarthritis: a systematic literature review.
Annals of the Rheumatic Diseases 2018 A. Moltó, L. Gensler, M.E.B. Clowse, H. Marzo-Ortega, A. Artignan, D. Goff-Leggett, S. Leonard, H.K. Resemann, E. Thurtle, N. de Peyrecave, C. Ecoffet, F. Förger -
A multiple imputation method based on weighted quantile regression models for longitudinal censored biomarker data with missing values at early visits.
BMC medical research methodology 2018 Lee M, Rahbar MH, Brown M, Gensler L, Weisman M, Diekman L, Reveille JD -
Successful treatment of mucous membrane pemphigoid with bortezomib.
JAAD case reports 2017 Saeed L, Schmidt TH, Gensler LS, Gross AJ, Fox LP, Scharschmidt TC, Gaensler K, Naik H, Rosenblum MA, Shinkai K -
Opioid Analgesic Use in Patients with Ankylosing Spondylitis: An Analysis of the Prospective Study of Outcomes in an Ankylosing Spondylitis Cohort.
The Journal of rheumatology 2017 Dau JD, Lee M, Ward MM, Gensler LS, Brown MA, Learch TJ, Diekman LA, Tahanan A, Rahbar MH, Weisman MH, Reveille JD -
Clinical Images: Ochronotic arthropathy.
Arthritis & rheumatology (Hoboken, N.J.) 2017 Jafri K, Gensler LS, Link TM -
Ethnicity and disease severity in ankylosing spondylitis a cross-sectional analysis of three ethnic groups.
Clinical rheumatology 2017 Jamalyaria F, Ward MM, Assassi S, Learch TJ, Lee M, Gensler LS, Brown MA, Diekman L, Tahanan A, Rahbar MH, Weisman MH, Reveille JD -
Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force.
Annals of the rheumatic diseases 2017 Smolen JS, Schöls M, Braun J, Dougados M, FitzGerald O, Gladman DD, Kavanaugh A, Landewé R, Mease P, Sieper J, Stamm T, Wit M, Aletaha D, Baraliakos X, Betteridge N, Bosch FVD, Coates LC, Emery P, … -
FRI0474 Does axial spondyloarthritis phenotype correlate with imaging morphotype?.
Annals of the Rheumatic Diseases 2017 X Baraliakos, A Szumski, HE Jones, L Gensler -
SAT0465 An integrated safety data analysis across all phase ii and phase iii clinical programs for ustekinumab in psoriatic arthritis, crohn's disease, and psoriasis.
Annals of the Rheumatic Diseases 2017 LS Gensler, E Hsia, C Gasink, B Randazzo, D Parenti, S Fakharzadeh, L-L Gao, SD Chakravarty -
Validity and Responsiveness of a 10-Item Patient-Reported Measure of Physical Function in a Rheumatoid Arthritis Clinic Population.
Arthritis care & research 2017 Wahl E, Gross A, Chernitskiy V, Trupin L, Gensler L, Chaganti K, Michaud K, Katz P, Yazdany J -
Cervical Spinal Fracture and Other Diagnoses Associated With Mortality in Hospitalized Ankylosing Spondylitis Patients.
Arthritis care & research 2017 Wysham KD, Murray SG, Hills N, Yelin E, Gensler LS -
FRI0398 Pharmacologic Therapy and Radiographic Progression in Ankylosing Spondylitis: A Growing Controversy.
Annals of the Rheumatic Diseases 2016 L. Gensler, J.D. Reveille, M.M. Ward, M.A. Brown, M. Rahbar, M. Lee, M.H. Weisman -
FRI0434 Prevalence of Structural Cardiac Disease and Diastolic Dysfunction in Axial Spondyloarthritis: A Prospective Case-Control Study.
Annals of the Rheumatic Diseases 2016 R. Reejhsinghani, K.M. Brown, N.B. Schiller, G. Yoon, E. Foster, L.S. Gensler -
SAT0380 Nsaids Modify The Effect of Tumor Necrosis Factor Inhibitors on New Bone Formation in Ankylosing Spondylitis.
Annals of the Rheumatic Diseases 2016 L. Gensler, J.D. Reveille, M.M. Ward, M.A. Brown, M. Rahbar, M. Lee, M.H. Weisman -
SAT0400 Clinical Factors Impacting Statin Usage in A Longitudinal Ankylosing Spondylitis Cohort.
Annals of the Rheumatic Diseases 2016 J. Dau, M. Weisman, M. Lee, M. Ward, M. Brown, L. Diekman, M. Rahbar, L. Gensler, J. Reveille -
Physical activity in axial spondyloarthritis-tails from bench to bedside.
Clinical rheumatology 2016 Gensler LS -
ECHOCARDIOGRAPHIC EVALUATION OF CARDIOVASCULAR DISEASE IN ANKYLOSING SPONDYLITIS: A PROSPECTIVE CASE-CONTROL STUDY.
Journal of the American College of Cardiology 2016 Risheen S. Reejhsinghani, Kathryn Brown, Nelson Schiller, Grace Yoon, Lianne Gensler, Elyse Foster -
National Lupus Hospitalization Trends Reveal Rising Rates of Herpes Zoster and Declines in Pneumocystis Pneumonia.
PloS one 2016 Murray SG, Schmajuk G, Trupin L, Gensler L, Katz PP, Yelin EH, Gansky SA, Yazdany J -
American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Arthritis care & research 2015 Ward MM, Deodhar A, Akl EA, Lui A, Ermann J, Gensler LS, Smith JA, Borenstein D, Hiratzka J, Weiss PF, Inman RD, Majithia V, Haroon N, Maksymowych WP, Joyce J, Clark BM, Colbert RA, Figgie MP, … -
American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Arthritis & rheumatology (Hoboken, N.J.) 2015 Ward MM, Deodhar A, Akl EA, Lui A, Ermann J, Gensler LS, Smith JA, Borenstein D, Hiratzka J, Weiss PF, Inman RD, Majithia V, Haroon N, Maksymowych WP, Joyce J, Clark BM, Colbert RA, Figgie MP, … -
Updates in adult-onset Still disease: Atypical cutaneous manifestations and associations with delayed malignancy.
Journal of the American Academy of Dermatology 2015 Sun NZ, Brezinski EA, Berliner J, Haemel A, Connolly MK, Gensler L, McCalmont TH, Shinkai K -
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
Nature communications 2015 Cortes A, Pulit SL, Leo PJ, Pointon JJ, Robinson PC, Weisman MH, Ward M, Gensler LS, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Bradbury LA, Elewaut D, Burgos-… -
Axial spondyloarthritis: the heart of the matter.
Clinical rheumatology 2015 Gensler LS -
ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients.
Annals of the rheumatic diseases 2015 Robinson PC, Costello ME, Leo P, Bradbury LA, Hollis K, Cortes A, Lee S, Joo KB, Shim SC, Weisman M, Ward M, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Jiang L… -
Reply: To PMID 25154344.
Arthritis & rheumatology (Hoboken, N.J.) 2015 Deodhar A, Sieper J, Reveille JD, van der Heijde D, Gensler LS, Landewé R, Spondyloarthritis Research and Treatment Network and Assessment of SpondyloArthritis international S -
114 Clinical features of axial spondyloarthritis.
2015 Lianne S. Gensler -
Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.
Arthritis & rheumatology (Hoboken, N.J.) 2015 Robinson PC, Claushuis TA, Cortes A, Martin TM, Evans DM, Leo P, Mukhopadhyay P, Bradbury LA, Cremin K, Harris J, Maksymowych WP, Inman RD, Rahman P, Haroon N, Gensler L, Powell JE, van der Horst-… -
Spontaneous, drug-induced, and drug-free remission in peripheral and axial spondyloarthritis.
Best practice & research. Clinical rheumatology 2014 Poddubnyy D, Gensler LS -
The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns.
Arthritis & rheumatology (Hoboken, N.J.) 2014 Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, … -
New population-based reference values for spinal mobility measures based on the 2009-2010 National Health and Nutrition Examination Survey.
Arthritis & rheumatology (Hoboken, N.J.) 2014 Assassi S, Weisman MH, Lee M, Savage L, Diekman L, Graham TA, Rahbar MH, Schall JI, Gensler LS, Deodhar AA, Clegg DO, Colbert RA, Reveille JD -
Spine fractures in ankylosing spondylitis: a case report and review of imaging as well as predisposing factors to falls and fractures.
Seminars in arthritis and rheumatism 2014 Fatemi G, Gensler LS, Learch TJ, Weisman MH -
Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis.
Annals of the rheumatic diseases 2014 Cortes A, Maksymowych WP, Wordsworth BP, Inman RD, Danoy P, Rahman P, Stone MA, Corr M, Gensler LS, Gladman D, Morgan A, Marzo-Ortega H, Ward MM, SPARCC (Spondyloarthritis Research Consortium of … -
Development and validation of the spondyloarthritis radiography module for calibration of readers using the modified Stoke Ankylosing Spondylitis Spine Score.
Arthritis care & research 2014 Maksymowych WP, Learch T, Lambert RG, Ward M, Haroon N, Inman R, Salonen D, Gensler LS, Weisman MH -
The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis.
Arthritis and rheumatism 2013 Haroon N, Inman RD, Learch TJ, Weisman MH, Lee M, Rahbar MH, Ward MM, Reveille JD, Gensler LS -
FRI0468 Socioeconomic status predicts radiographic progression in ankylosing spondylitis.
Annals of the Rheumatic Diseases 2013 L. S. Gensler, N. Haroon, J. D. Reveille, T. J. Learch, M. A. Brown, M. H. Weisman, R. D. Inman, M. M. Ward -
MICA, a gene contributing strong susceptibility to ankylosing spondylitis.
Annals of the rheumatic diseases 2013 Zhou X, Wang J, Zou H, Ward MM, Weisman MH, Espitia MG, Xiao X, Petersdorf E, Mignot E, Martin J, Gensler LS, Scheet P, Reveille JD -
SAT0273 Lower socioeconomic status and smoking are associated with greater radiographic disease severity in axial spondyloarthritis.
Annals of the Rheumatic Diseases 2013 L.S. Gensler, G. Yoon, T.J. Learch, M.M. Ward -
Functional limitations due to axial and peripheral joint impairments in patients with ankylosing spondylitis: are focused measures more informative?
Arthritis care & research 2013 Bethi S, Dasgupta A, Weisman MH, Learch TJ, Gensler LS, Davis JC, Reveille JD, Ward MM -
Glucocorticoids: complications to anticipate and prevent.
The Neurohospitalist 2013 Gensler LS -
Neutrophilic urticaria with systemic inflammation: a case series.
JAMA dermatology 2013 Belani H, Gensler L, Bajpai U, Meinhardt E, Graf J, Pincus L, Leslie KS -
Choosing wisely: the American College of Rheumatology's Top 5 list of things physicians and patients should question.
Arthritis care & research 2013 Yazdany J, Schmajuk G, Robbins M, Daikh D, Beall A, Yelin E, Barton J, Carlson A, Margaretten M, Zell J, Gensler LS, Kelly V, Saag K, King C, American College of Rheumatology Core Membership Group -
Regional radiographic damage and functional limitations in patients with ankylosing spondylitis: differences in early and late disease.
Arthritis care & research 2013 Ward MM, Learch TJ, Gensler LS, Davis JC, Reveille JD, Weisman MH -
Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?
Arthritis care & research 2012 Joshi R, Reveille JD, Brown MA, Weisman MH, Ward MM, Gensler LS, Wordsworth BP, Evans DM, Assassi S -
The "knowns" and "unknowns" of biologic therapy in ankylosing spondylitis.
The American journal of the medical sciences 2012 Gensler L, Inman R, Deodhar A -
Association of Sweet's Syndrome and Systemic Lupus Erythematosus.
Case reports in rheumatology 2011 Barton JL, Pincus L, Yazdany J, Richman N, McCalmont TH, Gensler L, Dall'era M, Fye KH -
112 Clinical features of ankylosing spondylitis.
Rheumatology 2011 Lianne Gensler -
Clinical, radiographic and functional differences between juvenile-onset and adult-onset ankylosing spondylitis: results from the PSOAS cohort.
Annals of the rheumatic diseases 2007 Gensler LS, Ward MM, Reveille JD, Learch TJ, Weisman MH, Davis JC -
Recognition and treatment of juvenile-onset spondyloarthritis.
Current opinion in rheumatology 2006 Gensler L, Davis JC -
Ten-year follow-up of a randomized trial of pravastatin in heart transplant patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Kobashigawa JA, Moriguchi JD, Laks H, Wener L, Hage A, Hamilton MA, Cogert G, Marquez A, Vassilakis ME, Patel J, Yeatman L -
Clinical problem-solving. One surprise after another.
The New England journal of medicine 2005 Leeper NJ, Wener LS, Dhaliwal G, Saint S, Wachter RM -
Longitudinal study of vascular remodeling in coronary arteries after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2000 Kobashigawa J, Wener L, Johnson J, Currier JW, Yeatman L, Cassem J, Tobis J -
Does use of intravascular ultrasound accelerate arteriopathy in heart transplant recipients?
American heart journal 1999 Son R, Tobis JM, Yeatman LA, Johnson JA, Wener LS, Kobashigawa JA